Page last updated: 2024-10-19

melatonin and Fatty Liver

melatonin has been researched along with Fatty Liver in 28 studies

Fatty Liver: Lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver. The abnormal lipid accumulation is usually in the form of TRIGLYCERIDES, either as a single large droplet or multiple small droplets. Fatty liver is caused by an imbalance in the metabolism of FATTY ACIDS.

Research Excerpts

ExcerptRelevanceReference
"To investigate, in the liver of adult offspring, the possible effects of melatonin supplementation in the obese mother during pregnancy and lactation."8.31Adult mice offspring of obese mothers supplemented with melatonin show lessened liver steatosis, inflammation, oxidative stress, and endoplasmic reticulum stress. ( Aguila, MB; Ajackson, M; Mandarim-de-Lacerda, CA; Marcondes-de-Castro, IA; Nagagata, BA, 2023)
"Non-alcoholic fatty liver disease (NAFLD), most common chronic hepatic pathology, that occurs in the developed countries is estimated at 1/3 of the population."6.79Effects of treatment with melatonin and tryptophan on liver enzymes, parameters of fat metabolism and plasma levels of cytokines in patients with non-alcoholic fatty liver disease--14 months follow up. ( Brzozowski, T; Celinski, K; Cichoz-Lach, H; Konturek, PC; Konturek, SJ; Korolczuk, A; Slomka, M, 2014)
"Melatonin (MT) plays a crucial role in the regulation of inflammatory response."5.91Melatonin alleviates lead-induced fatty liver in the common carps (Cyprinus carpio) via gut-liver axis. ( Miao, Z; Teng, X; Xu, S, 2023)
"Melatonin plays an important role in regulating circadian rhythms."5.48Melatonin improves insulin resistance and hepatic steatosis through attenuation of alpha-2-HS-glycoprotein. ( Baik, SH; Choi, DS; Choi, KM; Heo, JI; Kim, NH; Kim, SG; Seo, JA; Yoo, HJ; Yoon, DW; Yu, JH, 2018)
"Excess weight and obesity are severe public health threats worldwide."5.46Melatonin prevents obesity through modulation of gut microbiota in mice. ( Hong, F; Jia, L; Jin, X; Wang, J; Wang, S; Xu, P; Xue, T; Zhai, Y, 2017)
" Thus, the antihyperlipemic effect of melatonin, which was first discovered in hypercholesterolemia produced by short- or long-term administration of glucocorticoids, has now been proved to be rather universal and not simply anti-glucocorticoidal."5.27Effects of melatonin on genetic hypercholesterolemia in rats. ( Aoyama, H; Mori, N; Mori, W, 1988)
"To investigate, in the liver of adult offspring, the possible effects of melatonin supplementation in the obese mother during pregnancy and lactation."4.31Adult mice offspring of obese mothers supplemented with melatonin show lessened liver steatosis, inflammation, oxidative stress, and endoplasmic reticulum stress. ( Aguila, MB; Ajackson, M; Mandarim-de-Lacerda, CA; Marcondes-de-Castro, IA; Nagagata, BA, 2023)
" The altered proteins are related to the development of liver pathology, such as cirrhosis (α1-antiproteinase), thrombosis (fibrinogen, plasminogen), and inflammation (mannose-binding protein A, complement C4, complement factor B), contributing to liver steatosis or hepatic cell death."3.85High-fat diet-induced plasma protein and liver changes in obese rats can be attenuated by melatonin supplementation. ( Govitrapong, P; Isarankura-Na-Ayudhya, C; Kitidee, K; Klosen, P; Pannengpetch, S; Wongchitrat, P, 2017)
"Non-alcoholic fatty liver disease (NAFLD), most common chronic hepatic pathology, that occurs in the developed countries is estimated at 1/3 of the population."2.79Effects of treatment with melatonin and tryptophan on liver enzymes, parameters of fat metabolism and plasma levels of cytokines in patients with non-alcoholic fatty liver disease--14 months follow up. ( Brzozowski, T; Celinski, K; Cichoz-Lach, H; Konturek, PC; Konturek, SJ; Korolczuk, A; Slomka, M, 2014)
"Melatonin is a powerful endogenous antioxidant produced by the pineal gland and a variety of other because of its efficacy in organs; melatonin has been investigated to improve the outcome of organ transplantation by reducing ischemia-reperfusion injury and due to its synergic effect with organ preservation fluids."2.53Melatonin role preventing steatohepatitis and improving liver transplantation results. ( Alatorre-Jiménez, MA; Esteban-Zubero, E; García, JJ; García-Gil, FA; López-Pingarrón, L; Ramírez, JM; Reiter, RJ; Tan, DX, 2016)
"Melatonin is a remarkable molecule with diverse biological and physiological actions and is involved in the regulation of various important functions such as circadian rhythm, energy metabolism, the reproductive system, the cardiovascular system, and the neuropsychiatric system."2.52Melatonin: a potential intervention for hepatic steatosis. ( Huang, FF; Qu, S; Sun, H, 2015)
"Melatonin (MT) plays a crucial role in the regulation of inflammatory response."1.91Melatonin alleviates lead-induced fatty liver in the common carps (Cyprinus carpio) via gut-liver axis. ( Miao, Z; Teng, X; Xu, S, 2023)
"Melatonin plays an important role in regulating circadian rhythms."1.48Melatonin improves insulin resistance and hepatic steatosis through attenuation of alpha-2-HS-glycoprotein. ( Baik, SH; Choi, DS; Choi, KM; Heo, JI; Kim, NH; Kim, SG; Seo, JA; Yoo, HJ; Yoon, DW; Yu, JH, 2018)
"Excess weight and obesity are severe public health threats worldwide."1.46Melatonin prevents obesity through modulation of gut microbiota in mice. ( Hong, F; Jia, L; Jin, X; Wang, J; Wang, S; Xu, P; Xue, T; Zhai, Y, 2017)
"Melatonin has been shown to protect cells against oxidative and inflammatory damage via endocrine, paracrine and autocrine actions."1.43Melatonin protects female rats against steatosis and liver oxidative stress induced by oestrogen deficiency. ( Constantin, J; Gilglioni, EH; Hermoso, APM; Hermoso, DAM; Iwamoto, ELI; Mito, MS; Salgueiro-Pagadigorria, CL; Shimada, LBC, 2016)
"In addition, this treatment improved fatty liver, decreased hepatic triglyceride concentration and increased apolipoprotein B100 in liver tissue."1.37Melatonin improves mitochondrial respiratory chain activity and liver morphology in ob/ob mice. ( Fernández-Moreira, D; García Ruiz, I; García-Consuegra, I; Gómez-Izquierdo, E; Muñoz-Yagüe, T; Solís-Herruzo, JA; Solís-Muñoz, P, 2011)
"The mechanism by which nonalcoholic fatty liver disease (NAFLD) progresses into nonalcoholic steatohepatitis (NASH) is unknown, however, the major process is oxidative stress with increased production of reactive oxygen species and excessive inflammatory cytokine generation."1.36The pilot study of 3-month course of melatonin treatment of patients with nonalcoholic steatohepatitis: effect on plasma levels of liver enzymes, lipids and melatonin. ( Bielanski, W; Brzozowski, T; Gonciarz, M; Gonciarz, Z; Konturek, PC; Konturek, SJ; Mularczyk, A, 2010)
"Nonalcoholic steatohepatitis (NASH) may progress to advanced fibrosis and cirrhosis."1.35Melatonin ameliorates methionine- and choline-deficient diet-induced nonalcoholic steatohepatitis in rats. ( Akin, H; Atug, O; Avsar, E; Celikel, C; Eren, F; Imeryuz, N; Ozdogan, O; Ozguner, F; Tahan, G; Tahan, V; Tarcin, O; Tozun, N; Uzun, H, 2009)
" Thus, the antihyperlipemic effect of melatonin, which was first discovered in hypercholesterolemia produced by short- or long-term administration of glucocorticoids, has now been proved to be rather universal and not simply anti-glucocorticoidal."1.27Effects of melatonin on genetic hypercholesterolemia in rats. ( Aoyama, H; Mori, N; Mori, W, 1988)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.57)18.7374
1990's0 (0.00)18.2507
2000's3 (10.71)29.6817
2010's20 (71.43)24.3611
2020's4 (14.29)2.80

Authors

AuthorsStudies
Caballero, N1
Nieto, MA1
Suarez-Zamora, DA1
Moreno, S1
Remolina, CI1
Durán, D1
Vega, D1
Rodríguez-Urrego, PA1
Gómez, CP1
Rojas, DP1
Ramírez, A1
Martínez, O1
Baldión-Elorza, AM1
Hernández, LJ1
Quintero, J1
Budhiraja, S1
Tarai, B1
Jain, D1
Aggarwal, M2
Indrayan, A1
Das, P1
Mishra, RS1
Bali, S1
Mahajan, M1
Kirtani, J1
Tickoo, R1
Soni, P1
Nangia, V1
Lall, A1
Kishore, N1
Jain, A1
Singh, O1
Singh, N1
Kumar, A1
Saxena, P1
Dewan, A1
Aggarwal, R1
Mehra, M1
Jain, M1
Nakra, V1
Sharma, BD1
Pandey, PK1
Singh, YP1
Arora, V2
Jain, S2
Chhabra, R1
Tuli, P1
Boobna, V1
Joshi, A1
Gupta, R1
Aneja, P1
Dhall, S1
Chugh, IM1
Garg, S1
Mittal, V1
Gupta, A3
Jyoti, B1
Sharma, P1
Bhasin, P1
Singhal, RK1
Bhasin, A1
Vardani, A1
Pal, V1
Pande, DG1
Gulati, T1
Nayar, S1
Kalra, S1
Garg, M1
Pande, R1
Bag, P1
Sharma, J1
Handoo, A1
Burman, P1
Gupta, AK1
Choudhary, PN1
Gupta, P2
Joshi, S1
Tayal, N1
Gupta, M1
Khanna, A1
Kishore, S1
Sahay, S1
Dang, R1
Mishra, N1
Sekhri, S1
Srivastava, RC1
Agrawal, MB1
Mathur, M1
Banwari, A1
Khetarpal, S1
Pandove, S1
Bhasin, D1
Singh, H1
Midha, D1
Bhutani, A1
Kaur, M1
Singh, A1
Sharma, S1
Singla, K1
Sagar, V1
Dixit, A1
Bajpai, R1
Chachra, V1
Tyagi, P1
Saxena, S1
Uniyal, B1
Belwal, S1
Aier, I1
Singhal, M1
Khaduri, A1
Du, Z1
Liang, S1
Li, Y1
Zhang, J1
Yu, Y1
Xu, Q1
Sun, Z1
Duan, J1
Cao, N1
Hu, C1
Xia, B1
He, Y1
Huang, J1
Yuan, Z1
Deng, J1
Duan, P1
Liu, Q1
Guo, S1
Huang, Y1
Wei, X1
Liu, L1
Huo, F1
Huang, P1
Wu, Y1
Tian, W1
Miao, Z6
Teng, X3
Xu, S3
Ajackson, M2
Nagagata, BA2
Marcondes-de-Castro, IA2
Mandarim-de-Lacerda, CA2
Aguila, MB2
Veronesi, VB1
Pioli, MR1
de Souza, DN1
Teixeira, CJ1
Murata, GM1
Santos-Silva, JC1
Hecht, FB1
Vicente, JM1
Bordin, S1
Anhê, GF1
Wongchitrat, P1
Klosen, P1
Pannengpetch, S1
Kitidee, K1
Govitrapong, P1
Isarankura-Na-Ayudhya, C1
Báez-Ruiz, A1
Guerrero-Vargas, NN1
Cázarez-Márquez, F1
Sabath, E1
Basualdo, MDC1
Salgado-Delgado, R1
Escobar, C1
Buijs, RM1
Heo, JI1
Yoon, DW1
Yu, JH1
Kim, NH2
Yoo, HJ1
Seo, JA1
Kim, SG1
Choi, KM1
Baik, SH1
Choi, DS1
Rong, B1
Feng, R1
Liu, C1
Wu, Q1
Sun, C1
Zaouali, MA2
Boncompagni, E2
Reiter, RJ4
Bejaoui, M1
Freitas, I2
Pantazi, E1
Folch-Puy, E1
Abdennebi, HB1
Garcia-Gil, FA3
Roselló-Catafau, J2
Talu, MF1
Gül, M1
Alpaslan, N1
Yiğitcan, B1
Celinski, K3
Konturek, PC5
Slomka, M2
Cichoz-Lach, H2
Brzozowski, T4
Konturek, SJ5
Korolczuk, A1
Tiao, MM1
Huang, LT1
Chen, CJ1
Sheen, JM1
Tain, YL1
Chen, CC1
Kuo, HC1
Huang, YH1
Tang, KS1
Chu, EW1
Yu, HR1
Kim, SJ1
Kang, HS1
Lee, JH1
Park, JH1
Jung, CH1
Bae, JH1
Oh, BC1
Song, DK1
Baek, WK1
Im, SS1
Sun, H1
Huang, FF1
Qu, S1
Esteban-Zubero, E1
López-Pingarrón, L1
Alatorre-Jiménez, MA1
Ramírez, JM1
Tan, DX1
García, JJ2
Hermoso, DAM1
Shimada, LBC1
Gilglioni, EH1
Constantin, J1
Mito, MS1
Hermoso, APM1
Salgueiro-Pagadigorria, CL1
Iwamoto, ELI1
Xu, P1
Wang, J1
Hong, F1
Wang, S1
Jin, X1
Xue, T1
Jia, L1
Zhai, Y1
Tahan, V1
Atug, O1
Akin, H1
Eren, F1
Tahan, G1
Tarcin, O2
Uzun, H1
Ozdogan, O1
Imeryuz, N1
Ozguner, F1
Celikel, C1
Avsar, E1
Tozun, N1
Shieh, JM1
Wu, HT1
Cheng, KC1
Cheng, JT1
Padrissa-Altés, S1
Ben Abnennebi, H1
Gonciarz, M3
Gonciarz, Z2
Bielanski, W3
Mularczyk, A2
Solís-Muñoz, P1
Solís-Herruzo, JA1
Fernández-Moreira, D1
Gómez-Izquierdo, E1
García-Consuegra, I1
Muñoz-Yagüe, T1
García Ruiz, I1
Zaitone, S1
Hassan, N1
El-Orabi, N1
El-Awady, el-S1
Partyka, R1
Eszyk, J1
Pan, M1
Song, YL1
Xu, JM1
Gan, HZ1
Aoyama, H1
Mori, N1
Mori, W1

Reviews

2 reviews available for melatonin and Fatty Liver

ArticleYear
Melatonin: a potential intervention for hepatic steatosis.
    Lipids in health and disease, 2015, Jul-22, Volume: 14

    Topics: Adiposity; Animals; Antioxidants; Fatty Liver; Humans; Insulin Resistance; Lipid Metabolism; Melaton

2015
Melatonin role preventing steatohepatitis and improving liver transplantation results.
    Cellular and molecular life sciences : CMLS, 2016, Volume: 73, Issue:15

    Topics: Animals; Antioxidants; Fatty Liver; Humans; Liver; Liver Transplantation; Melatonin; Oxidative Stres

2016

Trials

4 trials available for melatonin and Fatty Liver

ArticleYear
Effects of treatment with melatonin and tryptophan on liver enzymes, parameters of fat metabolism and plasma levels of cytokines in patients with non-alcoholic fatty liver disease--14 months follow up.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2014, Volume: 65, Issue:1

    Topics: Adult; Cholesterol, LDL; Cytokines; Fatty Liver; Female; gamma-Glutamyltransferase; Humans; Lipid Me

2014
The effects of L-tryptophan and melatonin on selected biochemical parameters in patients with steatohepatitis.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2010, Volume: 61, Issue:5

    Topics: Adult; Antioxidants; Cytokines; Fatty Liver; Female; gamma-Glutamyltransferase; Hepatocytes; Humans;

2010
The effects of long-term melatonin treatment on plasma liver enzymes levels and plasma concentrations of lipids and melatonin in patients with nonalcoholic steatohepatitis: a pilot study.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2012, Volume: 63, Issue:1

    Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Blood Glucose; Chole

2012
Plasma insulin, leptin, adiponectin, resistin, ghrelin, and melatonin in nonalcoholic steatohepatitis patients treated with melatonin.
    Journal of pineal research, 2013, Volume: 54, Issue:2

    Topics: Adiponectin; Adult; Fatty Liver; Female; Ghrelin; Humans; Insulin; Leptin; Male; Melatonin; Resistin

2013

Other Studies

22 other studies available for melatonin and Fatty Liver

ArticleYear
    IJID regions, 2022, Volume: 3

    Topics: AMP-Activated Protein Kinases; Animals; Apolipoproteins E; Apoptosis; Asthenozoospermia; Calcium; eI

2022
Melatonin alleviates lead-induced fatty liver in the common carps (Cyprinus carpio) via gut-liver axis.
    Environmental pollution (Barking, Essex : 1987), 2023, Jan-15, Volume: 317

    Topics: Animals; Carps; Fatty Liver; Lead; Lipopolysaccharides; Liver; Melatonin

2023
Melatonin alleviates lead-induced fatty liver in the common carps (Cyprinus carpio) via gut-liver axis.
    Environmental pollution (Barking, Essex : 1987), 2023, Jan-15, Volume: 317

    Topics: Animals; Carps; Fatty Liver; Lead; Lipopolysaccharides; Liver; Melatonin

2023
Melatonin alleviates lead-induced fatty liver in the common carps (Cyprinus carpio) via gut-liver axis.
    Environmental pollution (Barking, Essex : 1987), 2023, Jan-15, Volume: 317

    Topics: Animals; Carps; Fatty Liver; Lead; Lipopolysaccharides; Liver; Melatonin

2023
Melatonin alleviates lead-induced fatty liver in the common carps (Cyprinus carpio) via gut-liver axis.
    Environmental pollution (Barking, Essex : 1987), 2023, Jan-15, Volume: 317

    Topics: Animals; Carps; Fatty Liver; Lead; Lipopolysaccharides; Liver; Melatonin

2023
Melatonin alleviates lead-induced fatty liver in the common carps (Cyprinus carpio) via gut-liver axis.
    Environmental pollution (Barking, Essex : 1987), 2023, Jan-15, Volume: 317

    Topics: Animals; Carps; Fatty Liver; Lead; Lipopolysaccharides; Liver; Melatonin

2023
Melatonin alleviates lead-induced fatty liver in the common carps (Cyprinus carpio) via gut-liver axis.
    Environmental pollution (Barking, Essex : 1987), 2023, Jan-15, Volume: 317

    Topics: Animals; Carps; Fatty Liver; Lead; Lipopolysaccharides; Liver; Melatonin

2023
Melatonin alleviates lead-induced fatty liver in the common carps (Cyprinus carpio) via gut-liver axis.
    Environmental pollution (Barking, Essex : 1987), 2023, Jan-15, Volume: 317

    Topics: Animals; Carps; Fatty Liver; Lead; Lipopolysaccharides; Liver; Melatonin

2023
Melatonin alleviates lead-induced fatty liver in the common carps (Cyprinus carpio) via gut-liver axis.
    Environmental pollution (Barking, Essex : 1987), 2023, Jan-15, Volume: 317

    Topics: Animals; Carps; Fatty Liver; Lead; Lipopolysaccharides; Liver; Melatonin

2023
Melatonin alleviates lead-induced fatty liver in the common carps (Cyprinus carpio) via gut-liver axis.
    Environmental pollution (Barking, Essex : 1987), 2023, Jan-15, Volume: 317

    Topics: Animals; Carps; Fatty Liver; Lead; Lipopolysaccharides; Liver; Melatonin

2023
Adult mice offspring of obese mothers supplemented with melatonin show lessened liver steatosis, inflammation, oxidative stress, and endoplasmic reticulum stress.
    Life sciences, 2023, Jan-01, Volume: 312

    Topics: AMP-Activated Protein Kinases; Animals; Diet, High-Fat; Dietary Supplements; Endoplasmic Reticulum S

2023
Adult mice offspring of obese mothers supplemented with melatonin show lessened liver steatosis, inflammation, oxidative stress, and endoplasmic reticulum stress.
    Life sciences, 2023, Jan-01, Volume: 312

    Topics: AMP-Activated Protein Kinases; Animals; Diet, High-Fat; Dietary Supplements; Endoplasmic Reticulum S

2023
Adult mice offspring of obese mothers supplemented with melatonin show lessened liver steatosis, inflammation, oxidative stress, and endoplasmic reticulum stress.
    Life sciences, 2023, Jan-01, Volume: 312

    Topics: AMP-Activated Protein Kinases; Animals; Diet, High-Fat; Dietary Supplements; Endoplasmic Reticulum S

2023
Adult mice offspring of obese mothers supplemented with melatonin show lessened liver steatosis, inflammation, oxidative stress, and endoplasmic reticulum stress.
    Life sciences, 2023, Jan-01, Volume: 312

    Topics: AMP-Activated Protein Kinases; Animals; Diet, High-Fat; Dietary Supplements; Endoplasmic Reticulum S

2023
Agomelatine reduces circulating triacylglycerides and hepatic steatosis in fructose-treated rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 141

    Topics: Acetamides; Animals; Apolipoproteins B; Body Weight; Carrier Proteins; Energy Intake; Fatty Liver; F

2021
High-fat diet-induced plasma protein and liver changes in obese rats can be attenuated by melatonin supplementation.
    Nutrition research (New York, N.Y.), 2017, Volume: 42

    Topics: alpha 1-Antitrypsin; Animals; Biomarkers; Blood Glucose; Blood Proteins; Body Weight; Complement C4;

2017
Food in synchrony with melatonin and corticosterone relieves constant light disturbed metabolism.
    The Journal of endocrinology, 2017, Volume: 235, Issue:3

    Topics: Adiposity; Animals; Chronobiology Disorders; Corticosterone; Fatty Liver; Feeding Methods; Glucose M

2017
Melatonin improves insulin resistance and hepatic steatosis through attenuation of alpha-2-HS-glycoprotein.
    Journal of pineal research, 2018, Volume: 65, Issue:2

    Topics: alpha-2-HS-Glycoprotein; Animals; Dietary Fats; Endoplasmic Reticulum Stress; Fatty Liver; Hep G2 Ce

2018
Reduced delivery of epididymal adipocyte-derived exosomal resistin is essential for melatonin ameliorating hepatic steatosis in mice.
    Journal of pineal research, 2019, Volume: 66, Issue:4

    Topics: Adipocytes; Animals; Exosomes; Fatty Liver; Male; Melatonin; Mice; Mice, Inbred C57BL; Random Alloca

2019
AMPK involvement in endoplasmic reticulum stress and autophagy modulation after fatty liver graft preservation: a role for melatonin and trimetazidine cocktail.
    Journal of pineal research, 2013, Volume: 55, Issue:1

    Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Endoplasmic Reticulum Stress; Fatty Liver; Histoc

2013
Calculation of melatonin and resveratrol effects on steatosis hepatis using soft computing methods.
    Computer methods and programs in biomedicine, 2013, Volume: 111, Issue:2

    Topics: Algorithms; Animals; Computer Systems; Fatty Liver; Humans; Image Processing, Computer-Assisted; Liv

2013
Melatonin in the regulation of liver steatosis following prenatal glucocorticoid exposure.
    BioMed research international, 2014, Volume: 2014

    Topics: Animals; Apoptosis; Cytokines; Fatty Liver; Female; Glucocorticoids; Liver; Male; Melatonin; Pregnan

2014
Melatonin ameliorates ER stress-mediated hepatic steatosis through miR-23a in the liver.
    Biochemical and biophysical research communications, 2015, Mar-13, Volume: 458, Issue:3

    Topics: Animals; Antioxidants; Cell Line; Cells, Cultured; Endoplasmic Reticulum Stress; Fatty Liver; Gene E

2015
Melatonin protects female rats against steatosis and liver oxidative stress induced by oestrogen deficiency.
    Life sciences, 2016, Jul-15, Volume: 157

    Topics: Animals; Estrogens; Fatty Acids; Fatty Liver; Female; Lipids; Liver; Melatonin; Mitochondria, Liver;

2016
Melatonin prevents obesity through modulation of gut microbiota in mice.
    Journal of pineal research, 2017, Volume: 62, Issue:4

    Topics: Animals; Bacteroidetes; Blotting, Western; Central Nervous System Depressants; Diet, High-Fat; Fatty

2017
Melatonin ameliorates methionine- and choline-deficient diet-induced nonalcoholic steatohepatitis in rats.
    Journal of pineal research, 2009, Volume: 46, Issue:4

    Topics: Animals; Apoptosis; Biomarkers; Choline; Choline Deficiency; Cytokines; Diet; Fatty Liver; Glutathio

2009
Melatonin ameliorates high fat diet-induced diabetes and stimulates glycogen synthesis via a PKCzeta-Akt-GSK3beta pathway in hepatic cells.
    Journal of pineal research, 2009, Volume: 47, Issue:4

    Topics: Animals; Antioxidants; Blotting, Western; Cell Line, Tumor; Diabetes Mellitus, Experimental; Dietary

2009
Melatonin protects steatotic and nonsteatotic liver grafts against cold ischemia and reperfusion injury.
    Journal of pineal research, 2011, Volume: 50, Issue:2

    Topics: Animals; Fatty Liver; Liver; Male; Melatonin; Nitric Oxide; Oxidative Stress; Rats; Rats, Zucker; Re

2011
The pilot study of 3-month course of melatonin treatment of patients with nonalcoholic steatohepatitis: effect on plasma levels of liver enzymes, lipids and melatonin.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2010, Volume: 61, Issue:6

    Topics: Alanine Transaminase; Antioxidants; Aspartate Aminotransferases; Blood Glucose; Cholesterol; Fatty L

2010
Melatonin improves mitochondrial respiratory chain activity and liver morphology in ob/ob mice.
    Journal of pineal research, 2011, Volume: 51, Issue:1

    Topics: Animals; Blotting, Western; Body Weight; Electron Transport Chain Complex Proteins; Fatty Liver; His

2011
Pentoxifylline and melatonin in combination with pioglitazone ameliorate experimental non-alcoholic fatty liver disease.
    European journal of pharmacology, 2011, Jul-15, Volume: 662, Issue:1-3

    Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Biomarkers; Body Weight; C

2011
Melatonin ameliorates nonalcoholic fatty liver induced by high-fat diet in rats.
    Journal of pineal research, 2006, Volume: 41, Issue:1

    Topics: Animals; Dietary Fats; Fatty Liver; Glutathione Peroxidase; Lipid Peroxidation; Liver; Male; Malondi

2006
Effects of melatonin on genetic hypercholesterolemia in rats.
    Atherosclerosis, 1988, Volume: 69, Issue:2-3

    Topics: Animals; Cholesterol; Fatty Liver; Hypercholesterolemia; Hypolipidemic Agents; Kidney; Liver; Male;

1988