melatonin has been researched along with Experimental Radiation Injuries in 32 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study tries to tests the hypothesis that "the intake of melatonin can minimize the morphological features of cell damage associated with radiation enteritis"." | 7.74 | Melatonin and roentgen irradiation-induced acute radiation enteritis in Albino rats: an animal model. ( Abdulwahed, SR; Abou El-Ghait, AT; Abu-Dief, EE; Ahmad, MH; Hussein, MR; Kamel, E, 2008) |
| "Adult male Syrian hamsters either placed in a short photoperiod alone or kept in a long photoperiod and given daily afternoon injections of the pineal indole melatonin (25 micrograms) exhibited splenic hypertrophy and extramedullary hematopoiesis in addition to a marked regression in testicular weight." | 7.67 | Splenic hypertrophy and extramedullary hematopoiesis induced in male Syrian hamsters by short photoperiod or melatonin injections and reversed by melatonin pellets or pinealectomy. ( Champney, TH; Hubbard, GB; Little, JC; Reiter, RJ; Vaughan, GM; Vaughan, MK, 1987) |
| "Melatonin treatment in the morning (P < 0." | 5.34 | Melatonin prevents inflammation and oxidative stress caused by abdominopelvic and total body irradiation of rat small intestine. ( Bilgihan, A; Caglar, G; Erdogan, D; Guney, HZ; Guney, Y; Hicsonmez, A; Kurtman, C; Nalca Andrieu, M; Ozel Turkcu, U; Take, G; Uluoglu, C; Yucel, B; Zengil, H, 2007) |
| "Clinical studies have shown that melatonin lowers the frequency of thrombocytopenia in patients with cancer undergoing radiotherapy or chemotherapy." | 3.96 | Melatonin protects against apoptosis of megakaryocytic cells via its receptors and the AKT/mitochondrial/caspase pathway. ( Chen, C; Chen, S; Chen, Y; He, Y; Li, L; Li, S; Wang, B; Xin, H; Xu, X; Yang, L; Yang, M; Ye, J; Zhang, C; Zhang, Q, 2020) |
| " Myocyte necrosis and fibrosis were diminished with melatonin while vasculitis was prevented." | 3.80 | Histopathological evaluation of melatonin as a protective agent in heart injury induced by radiation in a rat model. ( Erkal, HŞ; Gürses, I; Özeren, M; Serin, M; Yücel, N, 2014) |
| "This study tries to tests the hypothesis that "the intake of melatonin can minimize the morphological features of cell damage associated with radiation enteritis"." | 3.74 | Melatonin and roentgen irradiation-induced acute radiation enteritis in Albino rats: an animal model. ( Abdulwahed, SR; Abou El-Ghait, AT; Abu-Dief, EE; Ahmad, MH; Hussein, MR; Kamel, E, 2008) |
| "Adult male Syrian hamsters either placed in a short photoperiod alone or kept in a long photoperiod and given daily afternoon injections of the pineal indole melatonin (25 micrograms) exhibited splenic hypertrophy and extramedullary hematopoiesis in addition to a marked regression in testicular weight." | 3.67 | Splenic hypertrophy and extramedullary hematopoiesis induced in male Syrian hamsters by short photoperiod or melatonin injections and reversed by melatonin pellets or pinealectomy. ( Champney, TH; Hubbard, GB; Little, JC; Reiter, RJ; Vaughan, GM; Vaughan, MK, 1987) |
| "Treatment with melatonin after whole-body irradiation led to significant mitigation of radiation toxicity in both small and large intestines." | 1.56 | Mitigation of Radiation-Induced Gastrointestinal System Injury by Melatonin: A Histopathological Study. ( Bagheri, H; Javadi, A; Najafi, M; Sadeghi, H; Shekarchi, B, 2020) |
| "Melatonin pretreatment increased the expression of Cdkn1a and Rad50 in 8 and 24 h postradiations (2 and 8 Gy) (P < 0." | 1.48 | Radioprotective effect of melatonin on expression of ( Bazzaz, JT; Ghazi-Khansari, M; Izadi, P; Rezaeejam, H; Shirazi, A; Tabesh, GA; Valizadeh, M, 2018) |
| "Oral treatment with melatonin gel had a protective effect in the small intestine, which was associated with mitochondrial protection and, consequently, with a reduced inflammatory response, blunting the NF-κB/NLRP3 inflammasome signaling activation." | 1.46 | Melatonin protects rats from radiotherapy-induced small intestine toxicity. ( Acuña-Castroviejo, D; Escames, G; Fernández-Gil, B; Florido, J; García-Verdugo, JM; Guerra-Librero, A; López, LC; Luna, JD; Mendivil-Perez, M; Molina-Navarro, MM; Moneim, AE; Ortiz, F; Sayed, RK; Shen, YQ; Soto-Mercado, V, 2017) |
| "Melatonin was administered at a dose of 50 mg/kg through intraperitoneal injection, 15 min prior to radiation exposure." | 1.46 | Melatonin prevents possible radiotherapy-induced thyroid injury. ( Aktan, M; Alan, MA; Arıcıgil, M; Dündar, MA; Eryılmaz, MA; Fındık, S; Kılınç, İ; Yücel, A, 2017) |
| "Melatonin treatment led to malondialdehyde decrease after 40 days (p< 0." | 1.42 | The effect of melatonin on the liver of rats exposed to microwave radiation. ( Basic, J; Despotovic, M; Djordjevic, B; Jevtovic-Stoimenov, T; Kocic, G; Sokolovic, D; Sokolovic, DM; Veljkovic, A, 2015) |
| "Pretreatment with melatonin (100 μg 100 g(-1) bodyweight subcutaneously) improved the damage induced by UVB radiation on the skin and might act via a receptor-independent mechanism." | 1.40 | Melatonin improves ultraviolet B-induced oxidative damage and inflammatory conditions in cutaneous tissue of a diurnal Indian palm squirrel Funambulus pennanti. ( Goswami, S; Haldar, C, 2014) |
| "The modification of radiation-induced lung injuries by melatonin was studied by measuring changes in oxidative stress, cytokine expression and histopathology in the lung tissue of mice following irradiation." | 1.39 | Melatonin reduces X-ray radiation-induced lung injury in mice by modulating oxidative stress and cytokine expression. ( Han, JM; Huh, GJ; Jang, SS; Kim, HG; Lee, JS; Park, HJ; Son, CG, 2013) |
| "Melatonin-treated groups showed less apoptosis as indicated by a considerable decrease in caspace-3 immunoreactivity (P < 0." | 1.35 | Effect of melatonin and time of administration on irradiation-induced damage to rat testes. ( Erdogan, D; Göktas, G; Guney, Y; Helvacioglu, F; Hicsonmez, A; Ozbey, G; Ozkan, S; Take, G; Uluoglu, C; Yücel, B, 2009) |
| "Melatonin treatment caused increases in the degree of photoreceptor cell death when administered in the night to male pigmented Long-Evans rats, but melatonin administration during the day, either with or without exposure to HII, had little if any effect on photoreceptor cell survival." | 1.35 | Influence of dietary melatonin on photoreceptor survival in the rat retina: an ocular toxicity study. ( Chignell, CF; Roberts, JE; Wiechmann, AF, 2008) |
| "Melatonin was administered at a dose of 100 mg/kg using an intraperitoneal injection." | 1.34 | The histopathological evaluation of the effectiveness of melatonin as a protectant against acute lung injury induced by radiation therapy in a rat model. ( Erkal, HS; Gülbaş, H; Gürses, I; Serin, M; Yücel, N, 2007) |
| "Melatonin treatment in the morning (P < 0." | 1.34 | Melatonin prevents inflammation and oxidative stress caused by abdominopelvic and total body irradiation of rat small intestine. ( Bilgihan, A; Caglar, G; Erdogan, D; Guney, HZ; Guney, Y; Hicsonmez, A; Kurtman, C; Nalca Andrieu, M; Ozel Turkcu, U; Take, G; Uluoglu, C; Yucel, B; Zengil, H, 2007) |
| "Luzindole-treated eyes had ERG b-wave thresholds of 2." | 1.30 | The melatonin antagonist luzindole protects retinal photoreceptors from light damage in the rat. ( Bush, RA; Iuvone, PM; Sieving, PA; Sugawara, T, 1998) |
| "Melatonin is an indolamine hormone synthesized in the retina and pineal gland." | 1.28 | Melatonin increases photoreceptor susceptibility to light-induced damage. ( O'Steen, WK; Wiechmann, AF, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (6.25) | 18.7374 |
| 1990's | 2 (6.25) | 18.2507 |
| 2000's | 9 (28.13) | 29.6817 |
| 2010's | 14 (43.75) | 24.3611 |
| 2020's | 5 (15.63) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Q | 1 |
| Wang, Y | 1 |
| Du, L | 1 |
| Xu, C | 1 |
| Liu, Q | 1 |
| Fan, S | 1 |
| Kumar, A | 2 |
| Choudhary, S | 2 |
| Kumar, S | 1 |
| Adhikari, JS | 1 |
| Kapoor, S | 1 |
| Chaudhury, NK | 2 |
| Sadeghi, H | 1 |
| Bagheri, H | 1 |
| Shekarchi, B | 1 |
| Javadi, A | 1 |
| Najafi, M | 3 |
| Yang, M | 1 |
| Li, L | 1 |
| Chen, S | 1 |
| Li, S | 1 |
| Wang, B | 1 |
| Zhang, C | 1 |
| Chen, Y | 1 |
| Yang, L | 1 |
| Xin, H | 1 |
| Chen, C | 1 |
| Xu, X | 1 |
| Zhang, Q | 1 |
| He, Y | 1 |
| Ye, J | 1 |
| Wu, Q | 1 |
| Fang, L | 1 |
| Yang, Y | 1 |
| Wang, A | 1 |
| Chen, X | 1 |
| Sun, J | 1 |
| Wan, J | 1 |
| Hong, C | 1 |
| Tong, J | 1 |
| Tao, S | 1 |
| Tian, H | 1 |
| Fernández-Gil, B | 1 |
| Moneim, AE | 1 |
| Ortiz, F | 2 |
| Shen, YQ | 1 |
| Soto-Mercado, V | 1 |
| Mendivil-Perez, M | 1 |
| Guerra-Librero, A | 1 |
| Acuña-Castroviejo, D | 2 |
| Molina-Navarro, MM | 1 |
| García-Verdugo, JM | 1 |
| Sayed, RK | 1 |
| Florido, J | 1 |
| Luna, JD | 1 |
| López, LC | 2 |
| Escames, G | 2 |
| Arıcıgil, M | 1 |
| Dündar, MA | 1 |
| Yücel, A | 1 |
| Eryılmaz, MA | 1 |
| Aktan, M | 1 |
| Alan, MA | 1 |
| Fındık, S | 1 |
| Kılınç, İ | 1 |
| Shabeeb, D | 2 |
| Musa, AE | 2 |
| Keshavarz, M | 2 |
| Shirazi, A | 3 |
| Hassanzadeh, G | 2 |
| Hadian, MR | 2 |
| Samandari, H | 1 |
| Rezaeejam, H | 1 |
| Izadi, P | 1 |
| Bazzaz, JT | 1 |
| Ghazi-Khansari, M | 1 |
| Valizadeh, M | 1 |
| Tabesh, GA | 1 |
| Saha, N | 1 |
| Nowrouzi, A | 1 |
| Goswami, S | 1 |
| Haldar, C | 2 |
| Gürses, I | 2 |
| Özeren, M | 1 |
| Serin, M | 2 |
| Yücel, N | 2 |
| Erkal, HŞ | 2 |
| Doerrier, C | 1 |
| Dayoub, JC | 1 |
| Venegas, C | 1 |
| García, JA | 1 |
| López, A | 1 |
| Volt, H | 1 |
| Luna-Sánchez, M | 1 |
| Djordjevic, B | 1 |
| Sokolovic, D | 1 |
| Kocic, G | 1 |
| Veljkovic, A | 1 |
| Despotovic, M | 1 |
| Basic, J | 1 |
| Jevtovic-Stoimenov, T | 1 |
| Sokolovic, DM | 1 |
| Cakmak Karaer, I | 1 |
| Simsek, G | 1 |
| Yildiz, A | 1 |
| Vardi, N | 1 |
| Polat, A | 1 |
| Tanbek, K | 1 |
| Gurocak, S | 1 |
| Parlakpinar, H | 1 |
| Gumral, N | 1 |
| Saygin, M | 1 |
| Asci, H | 1 |
| Uguz, AC | 1 |
| Celik, O | 1 |
| Doguc, DK | 1 |
| Savas, HB | 1 |
| Comlekci, S | 1 |
| Hussein, MR | 1 |
| Abu-Dief, EE | 1 |
| Kamel, E | 1 |
| Abou El-Ghait, AT | 1 |
| Abdulwahed, SR | 1 |
| Ahmad, MH | 1 |
| Topkan, E | 1 |
| Tufan, H | 1 |
| Yavuz, AA | 1 |
| Bacanli, D | 1 |
| Onal, C | 1 |
| Kosdak, S | 1 |
| Yavuz, MN | 1 |
| Take, G | 2 |
| Erdogan, D | 2 |
| Helvacioglu, F | 1 |
| Göktas, G | 1 |
| Ozbey, G | 1 |
| Uluoglu, C | 2 |
| Yücel, B | 2 |
| Guney, Y | 2 |
| Hicsonmez, A | 2 |
| Ozkan, S | 1 |
| Liu, Y | 1 |
| Zhang, H | 1 |
| Zhang, L | 1 |
| Zhang, X | 1 |
| Xie, Y | 1 |
| Zhao, W | 1 |
| Sharma, S | 1 |
| Chaube, SK | 1 |
| Laxmi, T | 1 |
| Singh, SS | 1 |
| Jang, SS | 1 |
| Kim, HG | 1 |
| Lee, JS | 1 |
| Han, JM | 1 |
| Park, HJ | 1 |
| Huh, GJ | 1 |
| Son, CG | 1 |
| Li, T | 1 |
| Howland, HC | 1 |
| Ozguner, F | 1 |
| Aydin, G | 1 |
| Mollaoglu, H | 1 |
| Gökalp, O | 1 |
| Koyu, A | 1 |
| Cesur, G | 1 |
| Gülbaş, H | 1 |
| Guney, HZ | 1 |
| Ozel Turkcu, U | 1 |
| Caglar, G | 1 |
| Bilgihan, A | 1 |
| Nalca Andrieu, M | 1 |
| Kurtman, C | 1 |
| Zengil, H | 1 |
| Wiechmann, AF | 2 |
| Chignell, CF | 1 |
| Roberts, JE | 1 |
| Sugawara, T | 1 |
| Sieving, PA | 1 |
| Iuvone, PM | 1 |
| Bush, RA | 1 |
| O'Steen, WK | 1 |
| Vaughan, MK | 1 |
| Hubbard, GB | 1 |
| Champney, TH | 1 |
| Vaughan, GM | 1 |
| Little, JC | 1 |
| Reiter, RJ | 1 |
| Cremer-Bartels, G | 1 |
| Krause, K | 1 |
32 other studies available for melatonin and Experimental Radiation Injuries
| Article | Year |
|---|---|
The Effects of Melatonin Administration on Intestinal Injury Caused by Abdominal Irradiation from Mice.
Topics: Abdomen; Animals; Breast Neoplasms; Calgranulin B; Carrier Proteins; Cell Survival; Cytokine TWEAK; | 2021 |
Role of melatonin mediated G-CSF induction in hematopoietic system of gamma-irradiated mice.
Topics: Acute Radiation Syndrome; Animals; Gamma Rays; Granulocyte Colony-Stimulating Factor; Hematopoiesis; | 2022 |
Mitigation of Radiation-Induced Gastrointestinal System Injury by Melatonin: A Histopathological Study.
Topics: Animals; Apoptosis; Cobalt Radioisotopes; Gastrointestinal Tract; Inflammation; Intestine, Small; Ma | 2020 |
Melatonin protects against apoptosis of megakaryocytic cells via its receptors and the AKT/mitochondrial/caspase pathway.
Topics: Animals; Antineoplastic Agents; Apoptosis; Blood Platelets; Bone Marrow; Caspases; Cell Line, Tumor; | 2020 |
Protection of melatonin against long-term radon exposure-caused lung injury.
Topics: Air Pollutants, Radioactive; Animals; Antioxidants; Apoptosis; Caspase 3; Epithelial Cells; Humans; | 2021 |
Melatonin protects rats from radiotherapy-induced small intestine toxicity.
Topics: Animals; Apoptosis; Drug Evaluation, Preclinical; Gels; Intestinal Mucosa; Intestine, Small; Male; M | 2017 |
Melatonin prevents possible radiotherapy-induced thyroid injury.
Topics: Animals; Antioxidants; Female; Interleukin-10; Interleukin-1beta; Melatonin; Oxidants; Radiation Inj | 2017 |
Biochemical and Histopathological Evaluation of the Radioprotective Effects of Melatonin Against Gamma Ray-Induced Skin Damage.
Topics: Animals; Catalase; Gamma Rays; Male; Malondialdehyde; Melatonin; Oxidative Stress; Radiation Injurie | 2019 |
Radioprotective effect of melatonin on expression of
Topics: Animals; Cyclin-Dependent Kinase Inhibitor p21; DNA Breaks, Double-Stranded; DNA Repair; DNA Repair | 2018 |
PK-PD based optimal dose and time for orally administered supra-pharmacological dose of melatonin to prevent radiation induced mortality in mice.
Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; Drug Administration Schedule; F | 2019 |
Evaluation of the Radioprotective Effects of Melatonin Against Ionizing Radiation-Induced Muscle Tissue Injury.
Topics: Animals; Catalase; Male; Malondialdehyde; Melatonin; Muscle, Skeletal; Oxidative Stress; Radiation I | 2019 |
Melatonin improves ultraviolet B-induced oxidative damage and inflammatory conditions in cutaneous tissue of a diurnal Indian palm squirrel Funambulus pennanti.
Topics: Animals; Antioxidants; Interleukin-6; Male; Melatonin; Oxidative Stress; Oxidoreductases; Photosensi | 2014 |
Histopathological evaluation of melatonin as a protective agent in heart injury induced by radiation in a rat model.
Topics: Animals; Cardiomyopathies; Coronary Artery Disease; Coronary Vessels; Cytoprotection; Fibrosis; Male | 2014 |
Melatonin blunts the mitochondrial/NLRP3 connection and protects against radiation-induced oral mucositis.
Topics: Animals; Antioxidants; Carrier Proteins; Inflammasomes; Male; Melatonin; Mitochondria; NLR Family, P | 2015 |
The effect of melatonin on the liver of rats exposed to microwave radiation.
Topics: Animals; Antioxidants; Catalase; Dose-Response Relationship, Radiation; Lipid Peroxidation; Liver Di | 2015 |
Melatonin's protective effect on the salivary gland against ionized radiation damage in rats.
Topics: Animals; Catalase; Female; Glutathione; Glutathione Peroxidase; Malondialdehyde; Melatonin; Oxidativ | 2016 |
The effects of electromagnetic radiation (2450 MHz wireless devices) on the heart and blood tissue: role of melatonin.
Topics: Animals; Antioxidants; Ascorbic Acid; Electromagnetic Fields; Electromagnetic Radiation; Erythrocyte | 2016 |
Melatonin and roentgen irradiation-induced acute radiation enteritis in Albino rats: an animal model.
Topics: Animals; Cytoprotection; Disease Models, Animal; Enteritis; Epithelial Cells; Intestinal Mucosa; Int | 2008 |
Comparison of the protective effects of melatonin and amifostine on radiation-induced epiphyseal injury.
Topics: Amifostine; Animals; Bone Development; Dose Fractionation, Radiation; Extremities; Growth Plate; Mal | 2008 |
Effect of melatonin and time of administration on irradiation-induced damage to rat testes.
Topics: Animals; Apoptosis; Caspase 3; Immunohistochemistry; Male; Melatonin; Microscopy, Electron, Transmis | 2009 |
Melatonin modulates acute testicular damage induced by carbon ions in mice.
Topics: Acute Disease; Animals; Antioxidants; Apoptosis; Carbon; Comet Assay; DNA Damage; Glutathione; Male; | 2009 |
Long-term melatonin administration attenuates low-LET gamma-radiation-induced lymphatic tissue injury during the reproductively active and inactive phases of Indian palm squirrels (Funambulus pennanti).
Topics: Animals; Antioxidants; Apoptosis; Caspase 3; Circadian Rhythm; DNA Fragmentation; Gamma Rays; Leukoc | 2010 |
Melatonin reduces X-ray radiation-induced lung injury in mice by modulating oxidative stress and cytokine expression.
Topics: Animals; Base Sequence; Catalase; Cytokines; Female; Gene Expression; Glutathione; Immunohistochemis | 2013 |
The effects of constant and diurnal illumination of the pineal gland and the eyes on ocular growth in chicks.
Topics: Animals; Chickens; Circadian Rhythm; Eye; Hyperopia; Lighting; Melatonin; Photoperiod; Pineal Gland; | 2003 |
Prevention of mobile phone induced skin tissue changes by melatonin in rat: an experimental study.
Topics: Animals; Antioxidants; Cell Phone; Free Radical Scavengers; Male; Melatonin; Radiation Injuries, Exp | 2004 |
The histopathological evaluation of the effectiveness of melatonin as a protectant against acute lung injury induced by radiation therapy in a rat model.
Topics: Animals; Gamma Rays; Lung; Lung Injury; Macrophages, Alveolar; Male; Melatonin; Radiation Injuries, | 2007 |
Melatonin prevents inflammation and oxidative stress caused by abdominopelvic and total body irradiation of rat small intestine.
Topics: Animals; Antioxidants; Circadian Rhythm; Inflammation; Intestine, Small; Male; Melatonin; Oxidative | 2007 |
Influence of dietary melatonin on photoreceptor survival in the rat retina: an ocular toxicity study.
Topics: Animals; Cell Survival; Circadian Rhythm; Dose-Response Relationship, Drug; Female; Lighting; Male; | 2008 |
The melatonin antagonist luzindole protects retinal photoreceptors from light damage in the rat.
Topics: Animals; Dark Adaptation; Electroretinography; Light; Male; Melatonin; Photoreceptor Cells; Radiatio | 1998 |
Melatonin increases photoreceptor susceptibility to light-induced damage.
Topics: Animals; Circadian Rhythm; Injections, Intraperitoneal; Light; Male; Melatonin; Photoreceptor Cells; | 1992 |
Splenic hypertrophy and extramedullary hematopoiesis induced in male Syrian hamsters by short photoperiod or melatonin injections and reversed by melatonin pellets or pinealectomy.
Topics: Animals; Cricetinae; Drug Implants; Female; Hematopoiesis; Hypertrophy; Injections; Light; Male; Mel | 1987 |
[Effect of UVA on biosynthesis of melatonin in the retina].
Topics: Acetylserotonin O-Methyltransferase; Animals; Dose-Response Relationship, Radiation; Male; Melatonin | 1986 |