melatonin has been researched along with Esophageal Squamous Cell Carcinoma in 2 studies
Esophageal Squamous Cell Carcinoma: A carcinoma that originates usually from cells on the surface of the middle and lower third of the ESOPHAGUS. Tumor cells exhibit typical squamous morphology and form large polypoid lesions. Mutations in RNF6, LZTS1, TGFBR2, DEC1, and WWOX1 genes are associated with this cancer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oesophageal squamous cell carcinoma (ESCC) is the sixth most common cause of cancer-associated death in the world and novel therapeutic alternatives are urgently warranted." | 5.43 | Melatonin enhances sensitivity to fluorouracil in oesophageal squamous cell carcinoma through inhibition of Erk and Akt pathway. ( Bai, L; Chen, DL; Chen, LZ; Ju, HQ; Lu, YX; Mo, HY; Sheng, H; Wang, DS; Wang, F; Wu, QN; Xie, D; Xu, RH; Yu, HE; Yun, JP; Zeng, ZL, 2016) |
| "Melatonin treatment dose-dependently inhibited the proliferative ability and the expression of histone deacetylase 7 (HDAC7), c-Myc and ubiquitin-specific peptidase 10 (USP10) in ESCC cells (P < 0." | 1.72 | Melatonin inhibits ESCC tumor growth by mitigating the HDAC7/β-catenin/c-Myc positive feedback loop and suppressing the USP10-maintained HDAC7 protein stability. ( Feng, YT; Guo, K; Han, J; Hu, Y; Huang, D; Liu, D; Lu, D; Ma, ZQ; Pan, MH; Shao, CJ; Wang, JL; Yan, XL; Yang, B; Zhang, F; Zhang, YM; Zhang, YX, 2022) |
| "Oesophageal squamous cell carcinoma (ESCC) is the sixth most common cause of cancer-associated death in the world and novel therapeutic alternatives are urgently warranted." | 1.43 | Melatonin enhances sensitivity to fluorouracil in oesophageal squamous cell carcinoma through inhibition of Erk and Akt pathway. ( Bai, L; Chen, DL; Chen, LZ; Ju, HQ; Lu, YX; Mo, HY; Sheng, H; Wang, DS; Wang, F; Wu, QN; Xie, D; Xu, RH; Yu, HE; Yun, JP; Zeng, ZL, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ma, ZQ | 1 |
| Feng, YT | 1 |
| Guo, K | 1 |
| Liu, D | 1 |
| Shao, CJ | 1 |
| Pan, MH | 1 |
| Zhang, YM | 1 |
| Zhang, YX | 1 |
| Lu, D | 1 |
| Huang, D | 1 |
| Zhang, F | 1 |
| Wang, JL | 1 |
| Yang, B | 1 |
| Han, J | 1 |
| Yan, XL | 1 |
| Hu, Y | 1 |
| Lu, YX | 1 |
| Chen, DL | 1 |
| Wang, DS | 1 |
| Chen, LZ | 1 |
| Mo, HY | 1 |
| Sheng, H | 1 |
| Bai, L | 1 |
| Wu, QN | 1 |
| Yu, HE | 1 |
| Xie, D | 1 |
| Yun, JP | 1 |
| Zeng, ZL | 1 |
| Wang, F | 1 |
| Ju, HQ | 1 |
| Xu, RH | 1 |
2 other studies available for melatonin and Esophageal Squamous Cell Carcinoma
| Article | Year |
|---|---|
Melatonin inhibits ESCC tumor growth by mitigating the HDAC7/β-catenin/c-Myc positive feedback loop and suppressing the USP10-maintained HDAC7 protein stability.
Topics: Animals; beta Catenin; Catenins; Cell Proliferation; Esophageal Neoplasms; Esophageal Squamous Cell | 2022 |
Melatonin enhances sensitivity to fluorouracil in oesophageal squamous cell carcinoma through inhibition of Erk and Akt pathway.
Topics: Carcinoma, Squamous Cell; Cell Death; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Syne | 2016 |