melatonin has been researched along with Encephalopathy, Toxic in 26 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " Herein, we exposed mouse neuroblastoma cells (Neuro-2a cells) to different concentrations of cadmium chloride (CdCl2 ) (12." | 7.83 | Melatonin antagonizes cadmium-induced neurotoxicity by activating the transcription factor EB-dependent autophagy-lysosome machinery in mouse neuroblastoma cells. ( Chen, C; Chen, X; Guo, P; He, M; Li, G; Li, M; Li, Y; Lu, Y; Pi, H; Reiter, RJ; Tian, L; Tu, M; Xie, J; Xu, S; Yang, M; Yang, Z; Yu, Z; Zhang, L; Zhang, Y; Zhong, M; Zhou, Z, 2016) |
| " Since carvedilol and melatonin act as free-radical scavengers, this study examined the effect of carvedilol (10(-5) M) and melatonin (10(-5) M) on oxidative and cell damage induced by 3NP in N1E-115 neuroblastoma cells." | 7.75 | Neuroprotective effect of carvedilol and melatonin on 3-nitropropionic acid-induced neurotoxicity in neuroblastoma. ( Collado, JA; Espínola, C; Feijóo, M; Gómez, MM; Medina, FJ; Montilla, P; Moreno, E; Muñoz, C; Muntané, J; Ruiz, C; Tasset, I; Túnez, I, 2009) |
| " Employing human neuroblastoma cells, we found that 10 nM calyculin A (CA), a selective inhibitor of PP-2A and PP-1, significantly increased phosphorylation and accumulation of neurofilament (NF) in the cells." | 7.72 | Melatonin protects SH-SY5Y neuroblastoma cells from calyculin A-induced neurofilament impairment and neurotoxicity. ( Deng, YQ; Li, SP; Wang, JZ; Wang, XC; Wang, YP, 2004) |
| "Increased application of the pyrethroid insecticide deltamethrin has adverse effects on the cardiac system and neurobehavior on the non-target organisms, which has raised the public's attention." | 5.62 | Protective Effects of Spermidine and Melatonin on Deltamethrin-Induced Cardiotoxicity and Neurotoxicity in Zebrafish. ( Chen, D; Feng, X; Feng, Z; Gao, Q; Liu, X; Tang, Y; Zhao, X, 2021) |
| " Herein, we exposed mouse neuroblastoma cells (Neuro-2a cells) to different concentrations of cadmium chloride (CdCl2 ) (12." | 3.83 | Melatonin antagonizes cadmium-induced neurotoxicity by activating the transcription factor EB-dependent autophagy-lysosome machinery in mouse neuroblastoma cells. ( Chen, C; Chen, X; Guo, P; He, M; Li, G; Li, M; Li, Y; Lu, Y; Pi, H; Reiter, RJ; Tian, L; Tu, M; Xie, J; Xu, S; Yang, M; Yang, Z; Yu, Z; Zhang, L; Zhang, Y; Zhong, M; Zhou, Z, 2016) |
| " Since carvedilol and melatonin act as free-radical scavengers, this study examined the effect of carvedilol (10(-5) M) and melatonin (10(-5) M) on oxidative and cell damage induced by 3NP in N1E-115 neuroblastoma cells." | 3.75 | Neuroprotective effect of carvedilol and melatonin on 3-nitropropionic acid-induced neurotoxicity in neuroblastoma. ( Collado, JA; Espínola, C; Feijóo, M; Gómez, MM; Medina, FJ; Montilla, P; Moreno, E; Muñoz, C; Muntané, J; Ruiz, C; Tasset, I; Túnez, I, 2009) |
| " Employing human neuroblastoma cells, we found that 10 nM calyculin A (CA), a selective inhibitor of PP-2A and PP-1, significantly increased phosphorylation and accumulation of neurofilament (NF) in the cells." | 3.72 | Melatonin protects SH-SY5Y neuroblastoma cells from calyculin A-induced neurofilament impairment and neurotoxicity. ( Deng, YQ; Li, SP; Wang, JZ; Wang, XC; Wang, YP, 2004) |
| "Arsenic is a notorious metalloid that exists in the earth's crust and is considered toxic for humans and the environment." | 3.01 | The protective effect of natural or chemical compounds against arsenic-induced neurotoxicity: Cellular and molecular mechanisms. ( Barangi, S; Hosseinzadeh, H; Mehri, S; Shayan, M, 2023) |
| "Melatonin also plays a role in maintaining mitochondrial homeostasis." | 2.53 | Melatonin Attenuates Methamphetamine-Induced Neurotoxicity. ( Govitrapong, P; Wongprayoon, P, 2016) |
| "Melatonin is a multifunctional indolamine which counteracts virtually all pathophysiologic steps and displays significant beneficial effects against ONOO--induced cellular toxicity." | 2.44 | The use of melatonin to combat mustard toxicity. REVIEW. ( Korkmaz, A; Kunak, ZI; Paredes, SD; Reiter, RJ; Tan, DX; Yaren, H, 2008) |
| "Melatonin (MT), is a potent neuroprotective molecule." | 1.72 | Melatonin ameliorates bupivacaine-induced spinal neurotoxicity in rats by suppressing neuronal NLRP3 inflammasome activation. ( Chen, MY; Huang, LS; Ji, JM; Lai, J; Liu, JC; Luo, YP; Wei, LL; Yu, Y; Zhou, G, 2022) |
| "The thermal nociceptive/hyperalgesia tests were performed." | 1.72 | The Combination of Zinc and Melatonin Enhanced Neuroprotection and Attenuated Neuropathy in Oxaliplatin-Induced Neurotoxicity. ( Ali, M; Aziz, T, 2022) |
| "Increased application of the pyrethroid insecticide deltamethrin has adverse effects on the cardiac system and neurobehavior on the non-target organisms, which has raised the public's attention." | 1.62 | Protective Effects of Spermidine and Melatonin on Deltamethrin-Induced Cardiotoxicity and Neurotoxicity in Zebrafish. ( Chen, D; Feng, X; Feng, Z; Gao, Q; Liu, X; Tang, Y; Zhao, X, 2021) |
| "Melatonin treatment (3, 10 or 30 mg/kg, i." | 1.56 | Neuroprotective effects of melatonin against neurotoxicity induced by intranasal sodium dimethyldithiocarbamate administration in mice. ( Bobinski, F; Cunha, RA; Dafre, AL; de Menezes Moura, T; Fernandes, PA; Mack, JM; Markus, RP; Martins, DF; Prediger, RD; Walz, R, 2020) |
| "Melatonin is a well-known anti-inflammatory agent with significant neuroprotective activity." | 1.51 | Inhibition of SERPINA3N-dependent neuroinflammation is essential for melatonin to ameliorate trimethyltin chloride-induced neurotoxicity. ( Chen, C; Chen, M; Deng, P; He, M; Hong, H; Liu, M; Lu, Y; Pi, H; Reiter, RJ; Tian, L; Xi, Y; Xie, J; Xu, S; Yu, Z; Zhang, L; Zhou, C; Zhou, Z, 2019) |
| "Melatonin is a well-known potent endogenous antioxidant pharmacological agent with significant neuroprotective actions." | 1.48 | Acute dose of melatonin via Nrf2 dependently prevents acute ethanol-induced neurotoxicity in the developing rodent brain. ( Ali, T; Kim, MO; Rehman, SU; Shah, FA, 2018) |
| "Melatonin is an antioxidant and scavenger of free radicals secreted by the pineal gland." | 1.48 | Valproic Acid Induced Neurotoxicological Manifestations and its Mitigation by Melatonin in Rat Brain Synaptosomes. ( Chaudhary, S; Parvez, S, 2018) |
| "Melatonin pretreatment of the AlCl3 -administered rats reduced brain damage, and the tissues appeared like those of the control rats." | 1.42 | The protective properties of melatonin against aluminium-induced neuronal injury. ( Abdel Moneim, AE; Al-Olayan, EM; El-Khadragy, MF, 2015) |
| "Melatonin was pretreated along with Cd for four weeks to assess its neuroprotective activity against Cd intoxication." | 1.37 | Melatonin abrogates cadmium induced oxidative stress related neurotoxicity in rats. ( Muthumani, M; Prabu, SM; Shagirtha, K, 2011) |
| "When melatonin was given to lead-treated rats, it almost completely attenuated the increase in LPO products and restored GSH levels and SOD activity." | 1.32 | Prophylactic effect of melatonin in reducing lead-induced neurotoxicity in the rat. ( El-Sokkary, GH; Kamel, ES; Reiter, RJ, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (26.92) | 29.6817 |
| 2010's | 10 (38.46) | 24.3611 |
| 2020's | 9 (34.62) | 2.80 |
| Authors | Studies |
|---|---|
| Lai, J | 1 |
| Ji, JM | 1 |
| Chen, MY | 1 |
| Luo, YP | 1 |
| Yu, Y | 1 |
| Zhou, G | 1 |
| Wei, LL | 1 |
| Huang, LS | 1 |
| Liu, JC | 1 |
| Ali, M | 1 |
| Aziz, T | 1 |
| Shayan, M | 1 |
| Barangi, S | 1 |
| Hosseinzadeh, H | 1 |
| Mehri, S | 1 |
| Dong, L | 1 |
| Sun, Q | 1 |
| Qiu, H | 1 |
| Yang, K | 1 |
| Xiao, B | 1 |
| Xia, T | 1 |
| Wang, A | 1 |
| Gao, H | 1 |
| Zhang, S | 1 |
| Kang, H | 1 |
| Zhang, W | 1 |
| Jing, J | 1 |
| Huang, D | 1 |
| Zhang, L | 3 |
| Wang, J | 1 |
| Han, L | 1 |
| Liu, Z | 1 |
| Wang, Z | 1 |
| Gao, A | 1 |
| Liu, X | 1 |
| Gao, Q | 1 |
| Feng, Z | 1 |
| Tang, Y | 1 |
| Zhao, X | 1 |
| Chen, D | 1 |
| Feng, X | 1 |
| Mack, JM | 1 |
| de Menezes Moura, T | 1 |
| Bobinski, F | 1 |
| Martins, DF | 1 |
| Cunha, RA | 1 |
| Walz, R | 1 |
| Fernandes, PA | 1 |
| Markus, RP | 1 |
| Dafre, AL | 1 |
| Prediger, RD | 1 |
| Chaudhary, S | 2 |
| Sahu, U | 1 |
| Parvez, S | 2 |
| Abdollahzade, N | 1 |
| Babri, S | 1 |
| Majidinia, M | 1 |
| Song, X | 1 |
| Fiati Kenston, SS | 1 |
| Kong, L | 1 |
| Zhao, J | 1 |
| Ali, T | 1 |
| Rehman, SU | 1 |
| Shah, FA | 1 |
| Kim, MO | 1 |
| Esparza, JL | 1 |
| Gómez, M | 1 |
| Domingo, JL | 1 |
| Xi, Y | 1 |
| Liu, M | 1 |
| Xu, S | 2 |
| Hong, H | 1 |
| Chen, M | 1 |
| Tian, L | 2 |
| Xie, J | 2 |
| Deng, P | 1 |
| Zhou, C | 1 |
| He, M | 2 |
| Chen, C | 2 |
| Lu, Y | 2 |
| Reiter, RJ | 4 |
| Yu, Z | 2 |
| Pi, H | 2 |
| Zhou, Z | 2 |
| Wongprayoon, P | 1 |
| Govitrapong, P | 1 |
| Al-Olayan, EM | 1 |
| El-Khadragy, MF | 1 |
| Abdel Moneim, AE | 1 |
| Li, M | 1 |
| Yang, Z | 1 |
| Chen, X | 1 |
| Yang, M | 1 |
| Li, Y | 1 |
| Guo, P | 1 |
| Li, G | 1 |
| Tu, M | 1 |
| Zhong, M | 1 |
| Zhang, Y | 1 |
| Lin, AM | 1 |
| Feng, SF | 1 |
| Chao, PL | 1 |
| Yang, CH | 1 |
| Korkmaz, A | 1 |
| Kunak, ZI | 1 |
| Paredes, SD | 1 |
| Yaren, H | 1 |
| Tan, DX | 1 |
| Tasset, I | 1 |
| Espínola, C | 1 |
| Medina, FJ | 1 |
| Feijóo, M | 1 |
| Ruiz, C | 1 |
| Moreno, E | 1 |
| Gómez, MM | 1 |
| Collado, JA | 1 |
| Muñoz, C | 1 |
| Muntané, J | 1 |
| Montilla, P | 1 |
| Túnez, I | 1 |
| Pascual, R | 1 |
| Pilar Zamora-León, S | 1 |
| Pérez, N | 1 |
| Rojas, T | 1 |
| Rojo, A | 1 |
| José Salinas, M | 1 |
| Reyes, A | 1 |
| Bustamante, C | 1 |
| Shagirtha, K | 1 |
| Muthumani, M | 1 |
| Prabu, SM | 1 |
| El-Sokkary, GH | 2 |
| Kamel, ES | 1 |
| Li, SP | 1 |
| Deng, YQ | 1 |
| Wang, XC | 1 |
| Wang, YP | 1 |
| Wang, JZ | 1 |
| Abd-Elghaffar, SKh | 1 |
| Sharkawy, AA | 1 |
| Maharaj, DS | 1 |
| Maharaj, H | 1 |
| Daya, S | 1 |
| Glass, BD | 1 |
5 reviews available for melatonin and Encephalopathy, Toxic
| Article | Year |
|---|---|
The protective effect of natural or chemical compounds against arsenic-induced neurotoxicity: Cellular and molecular mechanisms.
Topics: Acetylcholinesterase; Animals; Arsenic; Brain; Humans; Melatonin; Neurotoxicity Syndromes; Oxidative | 2023 |
Molecular mechanisms of nickel induced neurotoxicity and chemoprevention.
Topics: Animals; Carnitine; Cell Line; Chemoprevention; Disease Models, Animal; DNA Damage; DNA, Mitochondri | 2017 |
Role of Melatonin in Aluminum-Related Neurodegenerative Disorders: a Review.
Topics: Aluminum; Animals; Antioxidants; Humans; Melatonin; Neurodegenerative Diseases; Neurotoxicity Syndro | 2019 |
Melatonin Attenuates Methamphetamine-Induced Neurotoxicity.
Topics: Adult; Animals; Central Nervous System Depressants; Central Nervous System Stimulants; Humans; Melat | 2016 |
The use of melatonin to combat mustard toxicity. REVIEW.
Topics: Animals; Antioxidants; Bioterrorism; Chemical Warfare Agents; Humans; Melatonin; Mustard Gas; Neurot | 2008 |
21 other studies available for melatonin and Encephalopathy, Toxic
| Article | Year |
|---|---|
Melatonin ameliorates bupivacaine-induced spinal neurotoxicity in rats by suppressing neuronal NLRP3 inflammasome activation.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Bupivacaine; Male; Melatonin; Microglia; Neurons; N | 2022 |
The Combination of Zinc and Melatonin Enhanced Neuroprotection and Attenuated Neuropathy in Oxaliplatin-Induced Neurotoxicity.
Topics: Animals; Antioxidants; Hyperalgesia; Male; Melatonin; Neural Cell Adhesion Molecules; Neuroprotectio | 2022 |
Melatonin protects against developmental PBDE-47 neurotoxicity by targeting the AMPK/mitophagy axis.
Topics: AMP-Activated Protein Kinases; Animals; Melatonin; Mitophagy; Neurotoxicity Syndromes; Rats; Ubiquit | 2023 |
The gut-brain axis involved in polystyrene nanoplastics-induced neurotoxicity via reprogramming the circadian rhythm-related pathways.
Topics: Animals; Brain-Gut Axis; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Circadian Rhythm; Melat | 2023 |
Protective Effects of Spermidine and Melatonin on Deltamethrin-Induced Cardiotoxicity and Neurotoxicity in Zebrafish.
Topics: Animals; Animals, Genetically Modified; Behavior, Animal; Cardiotoxicity; Disease Models, Animal; GA | 2021 |
Neuroprotective effects of melatonin against neurotoxicity induced by intranasal sodium dimethyldithiocarbamate administration in mice.
Topics: Administration, Intranasal; Animals; Behavior, Animal; Brain; Dimethyldithiocarbamate; Disease Model | 2020 |
Melatonin attenuates branch chain fatty acid induced apoptosis mediated neurodegeneration.
Topics: Animals; Antioxidants; Apoptosis; Behavior, Animal; Cell Line, Tumor; Cell Survival; Cerebellum; Cer | 2021 |
Attenuation of chronic arsenic neurotoxicity via melatonin in male offspring of maternal rats exposed to arsenic during conception: Involvement of oxidative DNA damage and inflammatory signaling cascades.
Topics: Animals; Antioxidants; Apoptosis; Arsenic; Female; Inflammation; Male; Melatonin; Neuroprotective Ag | 2021 |
Acute dose of melatonin via Nrf2 dependently prevents acute ethanol-induced neurotoxicity in the developing rodent brain.
Topics: Animals; Animals, Newborn; Antioxidants; Calcium-Binding Proteins; Cell Line, Transformed; Central N | 2018 |
Valproic Acid Induced Neurotoxicological Manifestations and its Mitigation by Melatonin in Rat Brain Synaptosomes.
Topics: Animals; Antioxidants; Brain; Glutathione; Lipid Peroxidation; Male; Melatonin; Membrane Potential, | 2018 |
Inhibition of SERPINA3N-dependent neuroinflammation is essential for melatonin to ameliorate trimethyltin chloride-induced neurotoxicity.
Topics: Acute-Phase Proteins; Animals; Hippocampus; Male; Melatonin; Mice; Mice, Inbred C57BL; Neurons; Neur | 2019 |
The protective properties of melatonin against aluminium-induced neuronal injury.
Topics: Aluminum Chloride; Aluminum Compounds; Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Protei | 2015 |
Melatonin antagonizes cadmium-induced neurotoxicity by activating the transcription factor EB-dependent autophagy-lysosome machinery in mouse neuroblastoma cells.
Topics: Active Transport, Cell Nucleus; Animals; Autophagy; Basic Helix-Loop-Helix Leucine Zipper Transcript | 2016 |
Melatonin inhibits arsenite-induced peripheral neurotoxicity.
Topics: Analysis of Variance; Animals; Arsenites; Ganglia, Spinal; Heat-Shock Proteins; Heme Oxygenase-1; HS | 2009 |
Neuroprotective effect of carvedilol and melatonin on 3-nitropropionic acid-induced neurotoxicity in neuroblastoma.
Topics: Animals; Carbazoles; Carvedilol; Free Radical Scavengers; Glutathione; L-Lactate Dehydrogenase; Lipi | 2009 |
Melatonin ameliorates neocortical neuronal dendritic impairment induced by toluene inhalation in the rat.
Topics: Animals; Dendrites; Female; Inhalation Exposure; Male; Melatonin; Neocortex; Neuroprotective Agents; | 2011 |
Melatonin abrogates cadmium induced oxidative stress related neurotoxicity in rats.
Topics: Acetylcholinesterase; Animals; Antioxidants; Biomarkers; Brain; Cadmium Chloride; Cadmium Poisoning; | 2011 |
Prophylactic effect of melatonin in reducing lead-induced neurotoxicity in the rat.
Topics: Animals; Antioxidants; Corpus Striatum; Hippocampus; Lead; Male; Melatonin; Neurotoxicity Syndromes; | 2003 |
Melatonin protects SH-SY5Y neuroblastoma cells from calyculin A-induced neurofilament impairment and neurotoxicity.
Topics: Cell Survival; Enzyme Inhibitors; Humans; Marine Toxins; Melatonin; Neuroblastoma; Neurofilament Pro | 2004 |
Aluminum-induced neurotoxicity and oxidative damage in rabbits: protective effect of melatonin.
Topics: Aluminum; Animals; Antioxidants; Apoptosis; Brain; Lipid Peroxidation; Male; Malondialdehyde; Melato | 2005 |
Melatonin and 6-hydroxymelatonin protect against iron-induced neurotoxicity.
Topics: Animals; Antioxidants; Hippocampus; Iron; Lipid Peroxidation; Male; Melatonin; Necrosis; Neurotoxici | 2006 |