melatonin has been researched along with Disease Exacerbation in 81 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " The study was performed in 14 metastatic breast cancer women treated by weekly epirubicin." | 9.09 | Chemoneuroendocrine therapy of metastatic breast cancer with persistent thrombocytopenia with weekly low-dose epirubicin plus melatonin: a phase II study. ( Ardizzoia, A; Barni, S; Giani, L; Lissoni, P; Malugani, F; Mandalà, M; Paolorossi, F; Tancini, G, 1999) |
| "We utilized the Pooled Resource Open-Access Clinical Trials (PRO-ACT) database to investigate whether melatonin use among patients with amyotrophic lateral sclerosis (ALS) was associated with slower disease progression and prolonged survival." | 8.02 | Melatonin may slow disease progression in amyotrophic lateral sclerosis: Findings from the Pooled Resource Open-Access ALS Clinic Trials database. ( Bald, EM; Nance, CS; Schultz, JL, 2021) |
| "We demonstrated that melatonin potently suppresses the migration and invasion of osteosarcoma cells." | 7.88 | Melatonin inhibits osteosarcoma stem cells by suppressing SOX9-mediated signaling. ( Fu, Q; He, J; Lai, L; Lian, W; Lin, N; Qu, H; Wang, C; Wang, Q; Xue, Y; Ye, Z; Zhong, L, 2018) |
| "Melatonin has a beneficial role in adult rat models of multiple sclerosis (MS)." | 7.85 | Melatonin exacerbates acute experimental autoimmune encephalomyelitis by enhancing the serum levels of lactate: A potential biomarker of multiple sclerosis progression. ( Dokoohaki, S; Farhadi, N; Ghanbari, A; Ghareghani, M; Ghavamizadeh, M; Khodadoust, S; Parishani, M; Sadeghi, H; Zibara, K, 2017) |
| "The melatonin deficiency hypothesis as a central mechanism in the pathogenesis of adolescent idiopathic scoliosis (AIS) is certainly intriguing." | 7.80 | Higher levels of melatonin in early stages of adolescent idiopathic scoliosis: toward a new scenario. ( Goultidis, TT; Kapetanos, GA; Papavasiliou, KA; Petropoulos, AS; Philippopoulos, A, 2014) |
| "The level of 6-oxymelatonin sulfate, the main metabolite of melatonin (MT), in morning urine samples from patients with metabolic syndrome (MS) suggests enhanced MT production at night." | 7.75 | [The role of melatonin in the development of metabolic syndrome]. ( Balliuzek, MF; Grinenko, TN; Kvetnaia, TV, 2009) |
| "The correlation of serum melatonin levels and curve progression in adolescent idiopathic scoliosis, and the effects of melatonin therapy in scoliotic patients with reduced levels of endogenous melatonin were studied in 40 adolescent patients with moderate to severe idiopathic scoliosis." | 7.75 | Serum melatonin levels in adolescent idiopathic scoliosis prediction and prevention for curve progression--a prospective study. ( Dubousset, J; Kimura, J; Machida, M; Yamada, T, 2009) |
| "To investigate whether a protein kinase C (PKC) inhibitor and melatonin prevent proliferative vitreoretinopathy (PVR)." | 7.73 | Inhibition of experimental proliferative vitreoretinopathy with protein kinase C inhibitor (chelerythrine chloride) and melatonin. ( Er, H; Mizrak, B; Parlakpinar, H; Turkoz, Y, 2006) |
| "In adolescent idiopathic scoliosis, neither the presentation with a stable spinal deformity, nor presentation with a severe deformity requiring surgery is associated with melatonin deficiency." | 7.70 | Total 24-hour melatonin secretion in adolescent idiopathic scoliosis. A case-control study. ( Fagan, AB; Kennaway, DJ; Sutherland, AD, 1998) |
| "Currently, colorectal cancer is emerging as the fourth leading cause of death and the third most common malignancy worldwide." | 6.66 | The Role of Melatonin in Colorectal Cancer. ( Dooghaie Moghadam, A; Eslami, P; Hashemi, MR; Iravani, S; Majidzadeh-A, K; Mansour-Ghanaei, A; Mansour-Ghanaei, F; Mehrvar, A; Moazzami, B, 2020) |
| "On the other hand, cerebral ischemia is a major cause of human disability all over the world." | 6.50 | The role of melatonin in multiple sclerosis, Huntington's disease and cerebral ischemia. ( Colín-González, AL; Escribano, BM; Santamaría, A; Túnez, I, 2014) |
| "Melatonin is a hormone synthesized in the pineal gland and has widespread physiological and pharmacological functions." | 5.72 | Melatonin may suppress lung adenocarcinoma progression via regulation of the circular noncoding RNA hsa_circ_0017109/miR-135b-3p/TOX3 axis. ( Duan, H; Duan, W; Li, X; Lu, G; Shao, C; Wang, J; Wang, Y; Wang, Z; Xie, M; Yan, X; Yu, W, 2022) |
| "Human hepatoma cell lines were treated with 1 and 2 mM melatonin, and functional assays were used to dissect melatonin's antitumor effect in HCC; small-RNA sequencing was performed to identify the microRNAs (miRNAs) involved in the anti-HCC activity of melatonin; and quantitative RT-PCR and Western blotting were used to elucidate how miRNAs regulate melatonin-mediated HCC suppression." | 5.48 | Melatonin Inhibits the Progression of Hepatocellular Carcinoma through MicroRNA Let7i-3p Mediated RAF1 Reduction. ( Chang, JL; Chen, CC; Chen, CY; Hsueh, C; Li, WS; Lian, JH; Wang, TH; Yeh, CT, 2018) |
| "Obesity is a common risk factor for non-alcoholic fatty liver disease (NAFLD)." | 5.43 | Hepatic Macrosteatosis Is Partially Converted to Microsteatosis by Melatonin Supplementation in ob/ob Mice Non-Alcoholic Fatty Liver Disease. ( Aleksic, M; Favero, G; Golic, I; Korac, A; Lavazza, A; Rezzani, R; Rodella, LF; Stacchiotti, A, 2016) |
| "The episodes of BA or COPD might be associated with elevated levels of oxidative stress." | 5.35 | Antioxidant enzymes and melatonin levels in patients with bronchial asthma and chronic obstructive pulmonary disease during stable and exacerbation periods. ( Akkaya, A; Beydilli, ED; Caliskan, S; Gumral, N; Naziroglu, M; Ongel, K; Ozguner, F; Sutcu, R, 2009) |
| "Treatment with melatonin slowed down age-related disturbances in estrous function most in the group exposed to interrupted treatment with the hormone." | 5.32 | The effect of melatonin treatment regimen on mammary adenocarcinoma development in HER-2/neu transgenic mice. ( Alimova, IN; Anisimov, VN; Baturin, DA; Manton, KG; Popovich, IG; Semenchenko, AV; Yashin, AI; Zabezhinski, MA, 2003) |
| " The study was performed in 14 metastatic breast cancer women treated by weekly epirubicin." | 5.09 | Chemoneuroendocrine therapy of metastatic breast cancer with persistent thrombocytopenia with weekly low-dose epirubicin plus melatonin: a phase II study. ( Ardizzoia, A; Barni, S; Giani, L; Lissoni, P; Malugani, F; Mandalà, M; Paolorossi, F; Tancini, G, 1999) |
| "We utilized the Pooled Resource Open-Access Clinical Trials (PRO-ACT) database to investigate whether melatonin use among patients with amyotrophic lateral sclerosis (ALS) was associated with slower disease progression and prolonged survival." | 4.02 | Melatonin may slow disease progression in amyotrophic lateral sclerosis: Findings from the Pooled Resource Open-Access ALS Clinic Trials database. ( Bald, EM; Nance, CS; Schultz, JL, 2021) |
| " Liver damage, markers of glucose metabolism, inflammation, intestinal barrier function and melatonin metabolism were determined." | 3.96 | Oral Supplementation of Sodium Butyrate Attenuates the Progression of Non-Alcoholic Steatohepatitis. ( Baumann, A; Bergheim, I; Brandt, A; Burkard, M; Jin, CJ; Nier, A; Sellmann, C; Venturelli, S, 2020) |
| "Objective To investigate the changes of plasma melatonin (MLT) level in patients with hemorrhagic fever with renal syndrome (HFRS) and the relationships between the MLT level and the disease stage or severity." | 3.88 | [The reduced level of plasma melatonin in HFRS patients is correlated with disease severity and stage]. ( Fan, L; Jin, B; Ma, Y; Song, C; Tang, K; Zhang, C; Zhang, Y, 2018) |
| "We demonstrated that melatonin potently suppresses the migration and invasion of osteosarcoma cells." | 3.88 | Melatonin inhibits osteosarcoma stem cells by suppressing SOX9-mediated signaling. ( Fu, Q; He, J; Lai, L; Lian, W; Lin, N; Qu, H; Wang, C; Wang, Q; Xue, Y; Ye, Z; Zhong, L, 2018) |
| "Melatonin has a beneficial role in adult rat models of multiple sclerosis (MS)." | 3.85 | Melatonin exacerbates acute experimental autoimmune encephalomyelitis by enhancing the serum levels of lactate: A potential biomarker of multiple sclerosis progression. ( Dokoohaki, S; Farhadi, N; Ghanbari, A; Ghareghani, M; Ghavamizadeh, M; Khodadoust, S; Parishani, M; Sadeghi, H; Zibara, K, 2017) |
| "MLT has been shown to exert anticancer activity through several biological mechanisms: antiproliferative action, stimulation of anticancer immunity, modulation of oncogene expression, and anti-inflammatory, anti-oxidant and anti-angiogenic effects." | 3.80 | Is there a role for melatonin in supportive care? ( Lissoni, P, 2002) |
| "The melatonin deficiency hypothesis as a central mechanism in the pathogenesis of adolescent idiopathic scoliosis (AIS) is certainly intriguing." | 3.80 | Higher levels of melatonin in early stages of adolescent idiopathic scoliosis: toward a new scenario. ( Goultidis, TT; Kapetanos, GA; Papavasiliou, KA; Petropoulos, AS; Philippopoulos, A, 2014) |
| "The synergetic use of Somatostatin, Melatonin, Retinoids, Vitamins C, D3, and E, Calcium, sulphated Aminoglucosides, and minimum doses of cyclophosphamide in a 70-year old male patient with inoperable scarcely differentiated oesophageal carcinoma, has provided, from the beginning of treatment in 1995 to the present date, an excellent quality of life, as well as a cure with functional recovery." | 3.75 | Complete objective response of oesophageal squamocellular carcinoma to biological treatment. ( Di Bella, G; Madarena, M, 2009) |
| "The level of 6-oxymelatonin sulfate, the main metabolite of melatonin (MT), in morning urine samples from patients with metabolic syndrome (MS) suggests enhanced MT production at night." | 3.75 | [The role of melatonin in the development of metabolic syndrome]. ( Balliuzek, MF; Grinenko, TN; Kvetnaia, TV, 2009) |
| "The correlation of serum melatonin levels and curve progression in adolescent idiopathic scoliosis, and the effects of melatonin therapy in scoliotic patients with reduced levels of endogenous melatonin were studied in 40 adolescent patients with moderate to severe idiopathic scoliosis." | 3.75 | Serum melatonin levels in adolescent idiopathic scoliosis prediction and prevention for curve progression--a prospective study. ( Dubousset, J; Kimura, J; Machida, M; Yamada, T, 2009) |
| "To investigate whether a protein kinase C (PKC) inhibitor and melatonin prevent proliferative vitreoretinopathy (PVR)." | 3.73 | Inhibition of experimental proliferative vitreoretinopathy with protein kinase C inhibitor (chelerythrine chloride) and melatonin. ( Er, H; Mizrak, B; Parlakpinar, H; Turkoz, Y, 2006) |
| "In adolescent idiopathic scoliosis, neither the presentation with a stable spinal deformity, nor presentation with a severe deformity requiring surgery is associated with melatonin deficiency." | 3.70 | Total 24-hour melatonin secretion in adolescent idiopathic scoliosis. A case-control study. ( Fagan, AB; Kennaway, DJ; Sutherland, AD, 1998) |
| "BACKGROUND Alzheimer's disease (AD) is a degenerative disease that is characterized by massive neuron devastations in the hippocampus and cortex." | 2.94 | Dietary Melatonin Therapy Alleviates the Lamina Cribrosa Damages in Patients with Mild Cognitive Impairments: A Double-Blinded, Randomized Controlled Study. ( Geng, Y; Hu, B; Sun, H; Xu, L; Yu, H, 2020) |
| "Melatonin concentration was measured by enzyme immunoassay." | 2.70 | Circadian serum melatonin profiles in patients suffering from chronic renal failure. ( Chrzanowski, W; Karasek, M; Swietoslawski, J; Szuflet, A; Zylinska, K, 2002) |
| "Melatonin was given orally at 20 mg/day in the evening for at least 2 months." | 2.70 | Anti-angiogenic activity of melatonin in advanced cancer patients. ( Bucovec, R; Conti, A; Lissoni, P; Maestroni, GJ; Malugani, F; Rovelli, F, 2001) |
| "Melatonin is an amphipathic indolamine molecule ubiquitously present in all organisms ranging from cyanobacteria to humans." | 2.66 | Melatonin: an endogenous miraculous indolamine, fights against cancer progression. ( Samanta, S, 2020) |
| "Glioblastoma is one of the most common brain tumors with high invasion and malignancy." | 2.66 | The effects of melatonin on signaling pathways and molecules involved in glioma. ( Asemi, Z; Neamati, F, 2020) |
| "Currently, colorectal cancer is emerging as the fourth leading cause of death and the third most common malignancy worldwide." | 2.66 | The Role of Melatonin in Colorectal Cancer. ( Dooghaie Moghadam, A; Eslami, P; Hashemi, MR; Iravani, S; Majidzadeh-A, K; Mansour-Ghanaei, A; Mansour-Ghanaei, F; Mehrvar, A; Moazzami, B, 2020) |
| "Childhood cancer management has improved considerably, with the overall objective of preventing early-life cancers completely." | 2.61 | The potential utility of melatonin in the treatment of childhood cancer. ( Chao, YH; Reiter, RJ; Su, SC; Wu, KH; Yang, SF; Yeh, CM, 2019) |
| "Melatonin is a natural indoleamine produced by the pineal gland that has many functions, including regulation of the circadian rhythm." | 2.58 | Melatonin and Cancer Hallmarks. ( Talib, WH, 2018) |
| "Although current therapies in chronic obstructive pulmonary disease (COPD) improve the quality of life, they do not satisfactorily reduce disease progression or mortality." | 2.55 | Geroprotectors as a therapeutic strategy for COPD - where are we now? ( Białas, AJ; Górski, P; Makowska, J; Miłkowska-Dymanowska, J; Piotrowski, WJ; Wardzynska, A, 2017) |
| "While the emphasis of melatonin/cancer research has been on the role of the indoleamine in restraining breast cancer, this is changing quickly with many cancer types having been shown to be susceptible to inhibition by melatonin." | 2.55 | Melatonin, a Full Service Anti-Cancer Agent: Inhibition of Initiation, Progression and Metastasis. ( Acuna-Castroviejo, D; Qin, L; Reiter, RJ; Rosales-Corral, SA; Tan, DX; Xu, K; Yang, SF, 2017) |
| "On the other hand, cerebral ischemia is a major cause of human disability all over the world." | 2.50 | The role of melatonin in multiple sclerosis, Huntington's disease and cerebral ischemia. ( Colín-González, AL; Escribano, BM; Santamaría, A; Túnez, I, 2014) |
| "Idiopathic scoliosis is a three-dimensional deformation of the spine." | 2.48 | Pathogenesis of idiopathic scoliosis: a review. ( Cugy, E; de Sèze, M, 2012) |
| "The classical symptoms of jet lag, such as tiredness during the day, mood swings and cognitive malfunction occur during this adjustment period." | 2.47 | [Rheumatism, jet lag and the body clock]. ( Pongratz, G; Straub, RH, 2011) |
| "Melatonin is a hormone with unique adaptive potential; its abnormal production and secretion rhythm trigger the mechanism of desynchronosis leading to organic pathology." | 2.45 | [Melatonin and its role in gastrointestinal pathology]. ( Rakhimova, OIu, 2009) |
| "Circadian rhythm disturbances, such as sleep disorders, are frequently seen in aging and are even more pronounced in Alzheimer's disease (AD)." | 2.44 | Disturbance and strategies for reactivation of the circadian rhythm system in aging and Alzheimer's disease. ( Swaab, DF; Wu, YH, 2007) |
| "Melatonin is a hormone synthesized in the pineal gland and has widespread physiological and pharmacological functions." | 1.72 | Melatonin may suppress lung adenocarcinoma progression via regulation of the circular noncoding RNA hsa_circ_0017109/miR-135b-3p/TOX3 axis. ( Duan, H; Duan, W; Li, X; Lu, G; Shao, C; Wang, J; Wang, Y; Wang, Z; Xie, M; Yan, X; Yu, W, 2022) |
| "Melatonin has been reported to have tumor-suppressive effects via comprehensive molecular mechanisms, and long non-coding RNAs (lncRNAs) may participate in this process." | 1.62 | Melatonin inhibits triple-negative breast cancer progression through the Lnc049808-FUNDC1 pathway. ( Huang, Z; Kong, Y; Li, X; Liu, P; Ou, S; Peng, C; Peng, F; Wu, S; Yang, A; Zhu, L, 2021) |
| "Having a history of optic neuritis is associated with improved sleep quality and executive functions but increased daytime sleepiness." | 1.56 | Sleep disturbance and cognitive decline in multiple sclerosis patients with isolated optic neuritis as the first demyelinating event. ( Akbayır, E; Arsoy, E; Benbir, G; Gencer, M; Karadeniz, D; Özyurt, S; Turan, S; Türkoğlu, R; Tüzün, E; Yılmaz, V, 2020) |
| "After implantation of tissue-isolated hepatoma 7288CTC xenografts, tumor growth rates were markedly delayed, and tumor cAMP levels, LA metabolism, the Warburg effect, and growth signaling activities were decreased in rats in bLAD compared with CWF daytime lighting." | 1.48 | Effect of Daytime Blue-enriched LED Light on the Nighttime Circadian Melatonin Inhibition of Hepatoma 7288CTC Warburg Effect and Progression. ( Anbalagan, M; Belancio, VP; Blask, DE; Dauchy, EM; Dauchy, RT; Dupepe, LM; Hill, SM; Wren-Dail, MA; Xiang, S, 2018) |
| "Human hepatoma cell lines were treated with 1 and 2 mM melatonin, and functional assays were used to dissect melatonin's antitumor effect in HCC; small-RNA sequencing was performed to identify the microRNAs (miRNAs) involved in the anti-HCC activity of melatonin; and quantitative RT-PCR and Western blotting were used to elucidate how miRNAs regulate melatonin-mediated HCC suppression." | 1.48 | Melatonin Inhibits the Progression of Hepatocellular Carcinoma through MicroRNA Let7i-3p Mediated RAF1 Reduction. ( Chang, JL; Chen, CC; Chen, CY; Hsueh, C; Li, WS; Lian, JH; Wang, TH; Yeh, CT, 2018) |
| "Obesity is a common risk factor for non-alcoholic fatty liver disease (NAFLD)." | 1.43 | Hepatic Macrosteatosis Is Partially Converted to Microsteatosis by Melatonin Supplementation in ob/ob Mice Non-Alcoholic Fatty Liver Disease. ( Aleksic, M; Favero, G; Golic, I; Korac, A; Lavazza, A; Rezzani, R; Rodella, LF; Stacchiotti, A, 2016) |
| "Melatonin was given at 5 or 10 mg/kg/d intraperitoneally, beginning 2 weeks after the start of CCl4 administration." | 1.42 | Melatonin limits the expression of profibrogenic genes and ameliorates the progression of hepatic fibrosis in mice. ( Crespo, I; Fernández, A; González-Gallego, J; Ortiz de Urbina, J; San-Miguel, B; Tuñón, MJ, 2015) |
| "Melatonin treatment improved the regularity, fragmentation and amplitude of the RAR in senescent fish, and it also improved sleep efficiency." | 1.39 | Rest-activity circadian rhythms in aged Nothobranchius korthausae. The effects of melatonin. ( Almaida-Pagán, PF; de Costa, J; Lucas-Sánchez, A; Madrid, JA; Martinez-Nicolas, A; Mendiola, P, 2013) |
| "The episodes of BA or COPD might be associated with elevated levels of oxidative stress." | 1.35 | Antioxidant enzymes and melatonin levels in patients with bronchial asthma and chronic obstructive pulmonary disease during stable and exacerbation periods. ( Akkaya, A; Beydilli, ED; Caliskan, S; Gumral, N; Naziroglu, M; Ongel, K; Ozguner, F; Sutcu, R, 2009) |
| "As melatonin has a major role in the regulation of sleep and other cyclical bodily activities and its synthesis is directly regulated by the SCN, we postulated that disturbed SCN function is likely to give rise to abnormal melatonin secretion in HD." | 1.35 | Delayed onset of the diurnal melatonin rise in patients with Huntington's disease. ( Aziz, NA; Frölich, M; Pijl, H; Roelfsema, F; Roos, RA; Schröder-van der Elst, JP; van der Bent, C, 2009) |
| "Melatonin has oncostatic effects on several types of cancer (breast, prostate, and colorectal cancers), while it can be self-defeating in others, such as lymphoma." | 1.35 | Effects of exogenous melatonin and circadian synchronization on tumor progression in melanoma-bearing C57BL6 mice. ( Alvarez, N; Madrid, JA; Otálora, BB; Rol, MA; Vicente, V, 2008) |
| "Treatment with melatonin slowed down age-related disturbances in estrous function most in the group exposed to interrupted treatment with the hormone." | 1.32 | The effect of melatonin treatment regimen on mammary adenocarcinoma development in HER-2/neu transgenic mice. ( Alimova, IN; Anisimov, VN; Baturin, DA; Manton, KG; Popovich, IG; Semenchenko, AV; Yashin, AI; Zabezhinski, MA, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (7.41) | 18.2507 |
| 2000's | 30 (37.04) | 29.6817 |
| 2010's | 32 (39.51) | 24.3611 |
| 2020's | 13 (16.05) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, X | 1 |
| Zhang, Y | 5 |
| Ren, Y | 1 |
| Li, J | 1 |
| Wang, Y | 3 |
| Wang, Z | 2 |
| Shao, C | 1 |
| Lu, G | 1 |
| Xie, M | 1 |
| Wang, J | 1 |
| Duan, H | 1 |
| Li, X | 4 |
| Yu, W | 1 |
| Duan, W | 1 |
| Yan, X | 1 |
| Türkoğlu, R | 1 |
| Benbir, G | 1 |
| Özyurt, S | 1 |
| Arsoy, E | 1 |
| Akbayır, E | 1 |
| Turan, S | 1 |
| Karadeniz, D | 1 |
| Yılmaz, V | 1 |
| Gencer, M | 1 |
| Tüzün, E | 1 |
| Iravani, S | 1 |
| Eslami, P | 1 |
| Dooghaie Moghadam, A | 1 |
| Moazzami, B | 1 |
| Mehrvar, A | 1 |
| Hashemi, MR | 1 |
| Mansour-Ghanaei, F | 1 |
| Mansour-Ghanaei, A | 1 |
| Majidzadeh-A, K | 1 |
| Neamati, F | 1 |
| Asemi, Z | 1 |
| Baumann, A | 1 |
| Jin, CJ | 1 |
| Brandt, A | 1 |
| Sellmann, C | 1 |
| Nier, A | 1 |
| Burkard, M | 1 |
| Venturelli, S | 1 |
| Bergheim, I | 1 |
| Xu, L | 1 |
| Yu, H | 1 |
| Sun, H | 1 |
| Hu, B | 1 |
| Geng, Y | 1 |
| Samanta, S | 1 |
| Lim, MA | 1 |
| Pranata, R | 1 |
| Jabłońska, J | 1 |
| Kluska, M | 1 |
| Lin, XJ | 1 |
| Liu, R | 1 |
| Li, C | 2 |
| Yi, X | 1 |
| Fu, B | 1 |
| Walker, MJ | 1 |
| Xu, XM | 1 |
| Sun, G | 1 |
| Lin, CH | 1 |
| Lan, NSR | 1 |
| Yeap, BB | 1 |
| Fegan, PG | 1 |
| Green, G | 1 |
| Rankin, JM | 1 |
| Dwivedi, G | 1 |
| Habibi, A | 1 |
| Karami, S | 1 |
| Varmira, K | 1 |
| Hadadi, M | 1 |
| Zhang, M | 1 |
| Li, Q | 1 |
| Lan, X | 1 |
| Zheng, J | 1 |
| Eskandari-Sedighi, G | 1 |
| Cortez, LM | 1 |
| Yang, J | 1 |
| Daude, N | 1 |
| Shmeit, K | 1 |
| Sim, V | 1 |
| Westaway, D | 1 |
| Weigand, S | 1 |
| O'Connor, M | 1 |
| Blažek, P | 1 |
| Kantenwein, V | 1 |
| Friedrich, L | 1 |
| Grebmer, C | 1 |
| Schaarschmidt, C | 1 |
| von Olshausen, G | 1 |
| Reents, T | 1 |
| Deisenhofer, I | 1 |
| Lennerz, C | 1 |
| Kolb, C | 1 |
| Iwata, H | 1 |
| Sassa, N | 1 |
| Kato, M | 1 |
| Murase, Y | 1 |
| Seko, S | 1 |
| Kawanishi, H | 1 |
| Hattori, R | 1 |
| Gotoh, M | 1 |
| Tsuzuki, T | 1 |
| Chen, D | 1 |
| Zhang, J | 1 |
| Chen, YP | 1 |
| Li, Y | 1 |
| Zhou, M | 1 |
| Waterhouse, GIN | 1 |
| Sun, J | 1 |
| Shi, W | 1 |
| Ai, S | 1 |
| Manne, ASN | 1 |
| Hegde, AR | 1 |
| Raut, SY | 1 |
| Rao, RR | 1 |
| Kulkarni, VI | 1 |
| Mutalik, S | 1 |
| Jafari, R | 1 |
| Hectors, SJ | 1 |
| Koehne de González, AK | 1 |
| Spincemaille, P | 1 |
| Prince, MR | 1 |
| Brittenham, GM | 1 |
| Bald, EM | 1 |
| Nance, CS | 1 |
| Schultz, JL | 1 |
| Mao, K | 1 |
| Luo, P | 1 |
| Geng, W | 1 |
| Xu, J | 1 |
| Liao, Y | 1 |
| Zhong, H | 1 |
| Ma, P | 1 |
| Tan, Q | 1 |
| Xia, H | 1 |
| Duan, L | 1 |
| Song, S | 1 |
| Long, D | 1 |
| Liu, Y | 1 |
| Yang, T | 1 |
| Wu, Y | 1 |
| Jin, Y | 1 |
| Yang, A | 1 |
| Peng, F | 1 |
| Zhu, L | 1 |
| Ou, S | 1 |
| Huang, Z | 1 |
| Wu, S | 1 |
| Peng, C | 1 |
| Liu, P | 1 |
| Kong, Y | 1 |
| Marjot, T | 1 |
| Ray, DW | 1 |
| Williams, FR | 1 |
| Tomlinson, JW | 1 |
| Armstrong, MJ | 1 |
| Reiter, RJ | 3 |
| Rosales-Corral, SA | 1 |
| Tan, DX | 1 |
| Acuna-Castroviejo, D | 2 |
| Qin, L | 1 |
| Yang, SF | 2 |
| Xu, K | 1 |
| Song, J | 1 |
| Whitcomb, DJ | 1 |
| Kim, BC | 1 |
| Shapiro, EG | 2 |
| Jones, SA | 1 |
| Escolar, ML | 2 |
| Miłkowska-Dymanowska, J | 1 |
| Białas, AJ | 1 |
| Makowska, J | 1 |
| Wardzynska, A | 1 |
| Górski, P | 1 |
| Piotrowski, WJ | 1 |
| Delaney, KA | 1 |
| Mitchell, JJ | 1 |
| Talib, WH | 1 |
| Qu, H | 1 |
| Xue, Y | 1 |
| Lian, W | 1 |
| Wang, C | 1 |
| He, J | 1 |
| Fu, Q | 1 |
| Zhong, L | 1 |
| Lin, N | 1 |
| Lai, L | 1 |
| Ye, Z | 1 |
| Wang, Q | 1 |
| Dauchy, RT | 2 |
| Wren-Dail, MA | 1 |
| Dupepe, LM | 1 |
| Hill, SM | 1 |
| Xiang, S | 1 |
| Anbalagan, M | 1 |
| Belancio, VP | 1 |
| Dauchy, EM | 1 |
| Blask, DE | 2 |
| Bondy, SC | 2 |
| Campbell, A | 1 |
| Wang, TH | 1 |
| Hsueh, C | 1 |
| Chen, CC | 1 |
| Li, WS | 1 |
| Yeh, CT | 1 |
| Lian, JH | 1 |
| Chang, JL | 1 |
| Chen, CY | 1 |
| Ma, S | 1 |
| Chen, J | 1 |
| Feng, J | 1 |
| Zhang, R | 1 |
| Fan, M | 1 |
| Han, D | 1 |
| Ren, J | 1 |
| Cao, F | 1 |
| Ma, Y | 2 |
| Tang, K | 1 |
| Song, C | 1 |
| Fan, L | 1 |
| Zhang, C | 1 |
| Jin, B | 1 |
| Chao, YH | 1 |
| Wu, KH | 1 |
| Yeh, CM | 1 |
| Su, SC | 1 |
| Gil-Martín, E | 1 |
| Egea, J | 1 |
| Romero, A | 1 |
| Amin, AH | 1 |
| El-Missiry, MA | 1 |
| Othman, AI | 1 |
| Ali, DA | 1 |
| Gouida, MS | 1 |
| Ismail, AH | 1 |
| Lucas-Sánchez, A | 1 |
| Almaida-Pagán, PF | 1 |
| Martinez-Nicolas, A | 1 |
| Madrid, JA | 2 |
| Mendiola, P | 1 |
| de Costa, J | 1 |
| Cook, A | 1 |
| Kim, J | 1 |
| Baranov, SV | 1 |
| Jiang, J | 1 |
| Smith, K | 1 |
| Cormier, K | 1 |
| Bennett, E | 1 |
| Browser, RP | 1 |
| Day, AL | 1 |
| Carlisle, DL | 1 |
| Ferrante, RJ | 1 |
| Wang, X | 1 |
| Friedlander, RM | 1 |
| Goultidis, TT | 1 |
| Papavasiliou, KA | 1 |
| Petropoulos, AS | 1 |
| Philippopoulos, A | 1 |
| Kapetanos, GA | 1 |
| Kuklina, EM | 1 |
| Escribano, BM | 1 |
| Colín-González, AL | 1 |
| Santamaría, A | 1 |
| Túnez, I | 1 |
| Crespo, I | 1 |
| San-Miguel, B | 1 |
| Fernández, A | 1 |
| Ortiz de Urbina, J | 1 |
| González-Gallego, J | 1 |
| Tuñón, MJ | 1 |
| Lucke-Wold, BP | 1 |
| Smith, KE | 1 |
| Nguyen, L | 1 |
| Turner, RC | 1 |
| Logsdon, AF | 1 |
| Jackson, GJ | 1 |
| Huber, JD | 1 |
| Rosen, CL | 1 |
| Miller, DB | 1 |
| Chen, SJ | 1 |
| Huang, SH | 1 |
| Chen, JW | 1 |
| Wang, KC | 1 |
| Yang, YR | 1 |
| Liu, PF | 1 |
| Lin, GJ | 1 |
| Sytwu, HK | 1 |
| Stacchiotti, A | 1 |
| Favero, G | 1 |
| Lavazza, A | 1 |
| Golic, I | 1 |
| Aleksic, M | 1 |
| Korac, A | 1 |
| Rodella, LF | 1 |
| Rezzani, R | 1 |
| Hu, K | 1 |
| Riemersma-van der Lek, RF | 1 |
| Patxot, M | 1 |
| Li, P | 1 |
| Shea, SA | 1 |
| Scheer, FA | 1 |
| Van Someren, EJ | 1 |
| Ghareghani, M | 1 |
| Dokoohaki, S | 1 |
| Ghanbari, A | 1 |
| Farhadi, N | 1 |
| Zibara, K | 1 |
| Khodadoust, S | 1 |
| Parishani, M | 1 |
| Ghavamizadeh, M | 1 |
| Sadeghi, H | 1 |
| Avakian, GN | 1 |
| Denisova, SV | 1 |
| Oleĭnikova, OM | 1 |
| Kurbanova, SA | 1 |
| El-Awady, HM | 1 |
| El-Wakkad, AS | 1 |
| Saleh, MT | 1 |
| Muhammad, SI | 1 |
| Ghaniema, EM | 1 |
| Machida, M | 2 |
| Dubousset, J | 2 |
| Yamada, T | 1 |
| Kimura, J | 1 |
| Rakhimova, OIu | 1 |
| Gumral, N | 1 |
| Naziroglu, M | 1 |
| Ongel, K | 1 |
| Beydilli, ED | 1 |
| Ozguner, F | 1 |
| Sutcu, R | 1 |
| Caliskan, S | 1 |
| Akkaya, A | 1 |
| Aziz, NA | 1 |
| Pijl, H | 1 |
| Frölich, M | 1 |
| Schröder-van der Elst, JP | 1 |
| van der Bent, C | 1 |
| Roelfsema, F | 1 |
| Roos, RA | 1 |
| Semenov, DIu | 1 |
| Tonoian, AG | 1 |
| Stepanov, IA | 1 |
| Gorchakova, MV | 1 |
| Shapkina, LG | 1 |
| Balliuzek, MF | 1 |
| Grinenko, TN | 1 |
| Kvetnaia, TV | 2 |
| Di Bella, G | 1 |
| Madarena, M | 1 |
| Evans, RW | 1 |
| Peres, MF | 1 |
| Brown, MA | 1 |
| Quan, SF | 1 |
| Eichling, PS | 1 |
| Pongratz, G | 1 |
| Straub, RH | 1 |
| Meng, T | 1 |
| Zheng, ZH | 1 |
| Liu, TT | 1 |
| Lin, L | 1 |
| de Sèze, M | 1 |
| Cugy, E | 1 |
| Jun, Z | 1 |
| Li, Z | 1 |
| Fang, W | 1 |
| Fengzhen, Y | 1 |
| Puyuan, W | 1 |
| Wenwen, L | 1 |
| Zhi, S | 1 |
| Callaghan, BD | 1 |
| Gerber, AM | 1 |
| Oosthuizen, GM | 1 |
| Crous, A | 1 |
| Anisimov, VN | 1 |
| Alimova, IN | 1 |
| Baturin, DA | 1 |
| Popovich, IG | 1 |
| Zabezhinski, MA | 1 |
| Manton, KG | 1 |
| Semenchenko, AV | 1 |
| Yashin, AI | 1 |
| Long, CO | 1 |
| Dougherty, J | 1 |
| Nunnari, G | 1 |
| Nigro, L | 1 |
| Palermo, F | 1 |
| Leto, D | 1 |
| Pomerantz, RJ | 1 |
| Cacopardo, B | 1 |
| Haase, CG | 1 |
| Faustmann, PM | 1 |
| Ferreira, AC | 1 |
| Martins, E | 1 |
| Afeche, SC | 1 |
| Cipolla-Neto, J | 1 |
| Costa Rosa, LF | 1 |
| Tailleux, A | 1 |
| Gozzo, A | 1 |
| Torpier, G | 1 |
| Martin-Nizard, F | 1 |
| Bonnefont-Rousselot, D | 1 |
| Lemdani, M | 1 |
| Furman, C | 1 |
| Foricher, R | 1 |
| Chevé, G | 1 |
| Yous, S | 1 |
| Micard, F | 1 |
| Bordet, R | 1 |
| Gardes-Albert, M | 1 |
| Lesieur, D | 1 |
| Teissier, E | 1 |
| Fruchart, JC | 1 |
| Fiévet, C | 1 |
| Duriez, P | 1 |
| Turgut, M | 1 |
| Başaloğlu, HK | 1 |
| Yenisey, C | 1 |
| Ozsunar, Y | 1 |
| Er, H | 1 |
| Turkoz, Y | 1 |
| Mizrak, B | 1 |
| Parlakpinar, H | 1 |
| Cutando, A | 1 |
| Galindo, P | 1 |
| Gómez-Moreno, G | 1 |
| Arana, C | 1 |
| Bolaños, J | 1 |
| Wang, HL | 1 |
| Wu, YH | 1 |
| Swaab, DF | 1 |
| Otálora, BB | 1 |
| Alvarez, N | 1 |
| Vicente, V | 1 |
| Rol, MA | 1 |
| Lenz, SP | 1 |
| Izui, S | 1 |
| Benediktsson, H | 1 |
| Hart, DA | 1 |
| Fagan, AB | 1 |
| Kennaway, DJ | 1 |
| Sutherland, AD | 1 |
| Lissoni, P | 3 |
| Tancini, G | 1 |
| Paolorossi, F | 1 |
| Mandalà, M | 1 |
| Ardizzoia, A | 1 |
| Malugani, F | 2 |
| Giani, L | 1 |
| Barni, S | 1 |
| Mocchegiani, E | 1 |
| Perissin, L | 1 |
| Santarelli, L | 1 |
| Tibaldi, A | 1 |
| Zorzet, S | 1 |
| Rapozzi, V | 1 |
| Giacconi, R | 1 |
| Bulian, D | 1 |
| Giraldi, T | 1 |
| Sauer, LA | 1 |
| Brainard, GC | 1 |
| Krause, JA | 1 |
| Ohta, Y | 1 |
| Kongo, M | 1 |
| Sasaki, E | 1 |
| Nishida, K | 1 |
| Ishiguro, I | 1 |
| Kozlova, IV | 1 |
| Osadchuk, MA | 1 |
| Kvetnoĭ, IM | 1 |
| Popuchiev, VV | 1 |
| Kennaway, D | 1 |
| Rovelli, F | 1 |
| Bucovec, R | 1 |
| Conti, A | 1 |
| Maestroni, GJ | 1 |
| Karasek, M | 1 |
| Szuflet, A | 1 |
| Chrzanowski, W | 1 |
| Zylinska, K | 1 |
| Swietoslawski, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Association of Anesthesia Technique With Morbidity and Mortality in Patients With COVID-19 and Surgery for Hip Fracture: a Retrospective Population Cohort Study[NCT05133648] | 1,000 participants (Anticipated) | Observational | 2023-01-05 | Active, not recruiting | |||
| Scoliosis Patients Aged 10-13 Years: Monitoring of Scoliosis by the Surface Topography[NCT02531945] | 125 participants (Actual) | Interventional | 2015-09-30 | Completed | |||
| Evaluation of Injectable Beta- Tricalcium Phosphate as an Occlusive Barrier Membrane in Treatment of Grade ii Furcation Involvement (Clinical and Radiographic Study)[NCT04443972] | 14 participants (Actual) | Interventional | 2018-04-12 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
24 reviews available for melatonin and Disease Exacerbation
| Article | Year |
|---|---|
The Role of Melatonin in Colorectal Cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Carcinogenesis; Colorectal Ne | 2020 |
The effects of melatonin on signaling pathways and molecules involved in glioma.
Topics: Animals; Apoptosis; Brain Neoplasms; Cell Differentiation; Cell Proliferation; Disease Progression; | 2020 |
Melatonin: an endogenous miraculous indolamine, fights against cancer progression.
Topics: Animals; Antioxidants; Carcinogenesis; Disease Progression; Humans; Melatonin; Neoplasms; Receptor, | 2020 |
Sleep and liver disease: a bidirectional relationship.
Topics: Body Temperature Regulation; Case-Control Studies; Chronic Disease; Cost of Illness; Disease Progres | 2021 |
Melatonin, a Full Service Anti-Cancer Agent: Inhibition of Initiation, Progression and Metastasis.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Transformation, | 2017 |
The role of melatonin in the onset and progression of type 3 diabetes.
Topics: Animals; Blood-Brain Barrier; Diabetes Mellitus; Disease Progression; Humans; Insulin Resistance; Me | 2017 |
Developmental and behavioral aspects of mucopolysaccharidoses with brain manifestations - Neurological signs and symptoms.
Topics: Brain; Child; Child Behavior; Child Development; Child, Preschool; Cognitive Dysfunction; Congresses | 2017 |
Geroprotectors as a therapeutic strategy for COPD - where are we now?
Topics: Aging; Disease Progression; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Me | 2017 |
Assessments of neurocognitive and behavioral function in the mucopolysaccharidoses.
Topics: Brain; Child; Child Behavior; Child Development; Child, Preschool; Cognitive Dysfunction; Congresses | 2017 |
Melatonin and Cancer Hallmarks.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Transformation, Neoplastic; Disease Pr | 2018 |
Mechanisms Underlying Tumor Suppressive Properties of Melatonin.
Topics: Aging; Animals; Anticarcinogenic Agents; Antioxidants; Carcinogenesis; Disease Models, Animal; Disea | 2018 |
The potential utility of melatonin in the treatment of childhood cancer.
Topics: Antineoplastic Agents; Antioxidants; Child; Disease Progression; Humans; Melatonin; Neoplasms | 2019 |
The emergence of melatonin in oncology: Focus on colorectal cancer.
Topics: Animals; Colorectal Neoplasms; Disease Progression; Epigenesis, Genetic; Humans; Melatonin; Neoplast | 2019 |
The role of melatonin in multiple sclerosis, Huntington's disease and cerebral ischemia.
Topics: Brain Ischemia; Disease Progression; Humans; Huntington Disease; Melatonin; Multiple Sclerosis | 2014 |
Sleep disruption and the sequelae associated with traumatic brain injury.
Topics: Adenosine Triphosphate; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Brain Injuries; Cogniti | 2015 |
[A role of circadian factors and melatonin in the development of epileptic paroxysms].
Topics: Brain; Circadian Rhythm; Disease Progression; Epilepsy; Humans; Melatonin; Prognosis | 2007 |
[Melatonin and its role in gastrointestinal pathology].
Topics: Disease Progression; Gastrointestinal Diseases; Humans; Melatonin | 2009 |
[Significance of melatonin and its receptors in pathogenesis of acute pancreatitis].
Topics: Animals; Biomarkers; Disease Progression; Humans; Melatonin; Pancreatitis, Acute Necrotizing; Recept | 2009 |
[Rheumatism, jet lag and the body clock].
Topics: Adaptation, Physiological; Adrenal Cortex Hormones; Antirheumatic Agents; Arthritis, Rheumatoid; Bio | 2011 |
Pathogenesis of idiopathic scoliosis: a review.
Topics: Adolescent; Animals; Biomechanical Phenomena; Bone Development; Calmodulin; Child; Disease Models, A | 2012 |
What's new in Alzheimer's disease?
Topics: Activities of Daily Living; Alzheimer Disease; Anti-Inflammatory Agents, Non-Steroidal; Anticholeste | 2003 |
Disturbance and strategies for reactivation of the circadian rhythm system in aging and Alzheimer's disease.
Topics: Aging; Alzheimer Disease; Biological Clocks; Circadian Rhythm; Disease Progression; Humans; Melatoni | 2007 |
[Possible role of the pineal gland in the pathogenesis of idiopathic scoliosis. Experimental and clinical studies].
Topics: Animals; Blood Platelets; Calmodulin; Chickens; Disease Models, Animal; Disease Progression; Growth | 2001 |
Is there a role for melatonin in supportive care?
Topics: Adjuvants, Immunologic; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Clinical Trials as To | 2002 |
6 trials available for melatonin and Disease Exacerbation
| Article | Year |
|---|---|
Dietary Melatonin Therapy Alleviates the Lamina Cribrosa Damages in Patients with Mild Cognitive Impairments: A Double-Blinded, Randomized Controlled Study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; China; Cognitive Dysf | 2020 |
Progression of Dementia Assessed by Temporal Correlations of Physical Activity: Results From a 3.5-Year, Longitudinal Randomized Controlled Trial.
Topics: Aged; Aged, 80 and over; Circadian Rhythm; Dementia; Disease Progression; Double-Blind Method; Exerc | 2016 |
Chemoneuroendocrine therapy of metastatic breast cancer with persistent thrombocytopenia with weekly low-dose epirubicin plus melatonin: a phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Neoplasms; Breast Neoplasms | 1999 |
Anti-angiogenic activity of melatonin in advanced cancer patients.
Topics: Adult; Aged; Bone Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; C | 2001 |
Is there a role for melatonin in supportive care?
Topics: Adjuvants, Immunologic; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Clinical Trials as To | 2002 |
Circadian serum melatonin profiles in patients suffering from chronic renal failure.
Topics: Adult; Blood Pressure; Circadian Rhythm; Creatinine; Disease Progression; Female; Humans; Kidney Fai | 2002 |
52 other studies available for melatonin and Disease Exacerbation
| Article | Year |
|---|---|
Melatonin prevents allergic airway inflammation in epicutaneously sensitized mice.
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Dermatitis, Allergic Contact; Disease Models, Animal; | 2021 |
Melatonin may suppress lung adenocarcinoma progression via regulation of the circular noncoding RNA hsa_circ_0017109/miR-135b-3p/TOX3 axis.
Topics: Adenocarcinoma of Lung; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Diseas | 2022 |
Sleep disturbance and cognitive decline in multiple sclerosis patients with isolated optic neuritis as the first demyelinating event.
Topics: Adult; Biomarkers; Cognitive Dysfunction; Disease Progression; Enzyme-Linked Immunosorbent Assay; Fe | 2020 |
Oral Supplementation of Sodium Butyrate Attenuates the Progression of Non-Alcoholic Steatohepatitis.
Topics: Animals; Butyric Acid; Cholesterol, Dietary; Diet, High-Fat; Dietary Supplements; Disease Models, An | 2020 |
Topics: Acute Coronary Syndrome; Adolescent; Adsorption; Adult; Aged; Animals; Aspergillus; Aspergillus oryz | 2021 |
Melatonin may slow disease progression in amyotrophic lateral sclerosis: Findings from the Pooled Resource Open-Access ALS Clinic Trials database.
Topics: Adult; Amyotrophic Lateral Sclerosis; Databases, Factual; Disease Progression; Female; Humans; Linea | 2021 |
An Integrative Transcriptomic and Metabolomic Study Revealed That Melatonin Plays a Protective Role in Chronic Lung Inflammation by Reducing Necroptosis.
Topics: Animals; Biomarkers; Case-Control Studies; Disease Models, Animal; Disease Progression; Female; Gene | 2021 |
Melatonin inhibits triple-negative breast cancer progression through the Lnc049808-FUNDC1 pathway.
Topics: Base Sequence; Cell Line, Tumor; Disease Progression; Gene Expression Regulation, Neoplastic; Gene K | 2021 |
Melatonin inhibits osteosarcoma stem cells by suppressing SOX9-mediated signaling.
Topics: Animals; Cell Line, Tumor; Cell Movement; Cell Separation; Cell Survival; Disease Progression; Epith | 2018 |
Effect of Daytime Blue-enriched LED Light on the Nighttime Circadian Melatonin Inhibition of Hepatoma 7288CTC Warburg Effect and Progression.
Topics: Animals; Carcinoma, Hepatocellular; Circadian Rhythm; Disease Progression; Glycolysis; Heterografts; | 2018 |
Melatonin Inhibits the Progression of Hepatocellular Carcinoma through MicroRNA Let7i-3p Mediated RAF1 Reduction.
Topics: 3' Untranslated Regions; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferat | 2018 |
Melatonin Ameliorates the Progression of Atherosclerosis via Mitophagy Activation and NLRP3 Inflammasome Inhibition.
Topics: Animals; Atherosclerosis; Disease Progression; Forkhead Box Protein O3; Free Radical Scavengers; Inf | 2018 |
[The reduced level of plasma melatonin in HFRS patients is correlated with disease severity and stage].
Topics: Case-Control Studies; Disease Progression; Enzyme-Linked Immunosorbent Assay; Hemorrhagic Fever with | 2018 |
Ameliorative effects of melatonin against solid Ehrlich carcinoma progression in female mice.
Topics: Animals; Apoptosis; Carcinoma, Ehrlich Tumor; Cell Line, Tumor; Cell Proliferation; Disease Progress | 2019 |
Rest-activity circadian rhythms in aged Nothobranchius korthausae. The effects of melatonin.
Topics: Aging; Animals; Chronobiology Disorders; Circadian Rhythm; Cyprinodontiformes; Disease Progression; | 2013 |
Melatonin inhibits the caspase-1/cytochrome c/caspase-3 cell death pathway, inhibits MT1 receptor loss and delays disease progression in a mouse model of amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Analysis of Variance; Animals; Antioxidants; Caspase 3; Cell Death; C | 2013 |
Higher levels of melatonin in early stages of adolescent idiopathic scoliosis: toward a new scenario.
Topics: Adolescent; Biomarkers; Case-Control Studies; Disease Progression; Female; Humans; Male; Melatonin; | 2014 |
Melatonin as potential inducer of Th17 cell differentiation.
Topics: Autoimmune Diseases; Cell Differentiation; Disease Progression; Female; Humans; Immune System; Inter | 2014 |
Melatonin limits the expression of profibrogenic genes and ameliorates the progression of hepatic fibrosis in mice.
Topics: Actins; Animals; Carbon Tetrachloride; Collagen; Cytokines; Disease Progression; Gene Expression; He | 2015 |
Melatonin enhances interleukin-10 expression and suppresses chemotaxis to inhibit inflammation in situ and reduce the severity of experimental autoimmune encephalomyelitis.
Topics: Animals; Cell Proliferation; Cells, Cultured; Chemotaxis; Disease Progression; Encephalomyelitis, Au | 2016 |
Hepatic Macrosteatosis Is Partially Converted to Microsteatosis by Melatonin Supplementation in ob/ob Mice Non-Alcoholic Fatty Liver Disease.
Topics: Animals; Antioxidants; beta Catenin; Calnexin; Disease Models, Animal; Disease Progression; Endoplas | 2016 |
Melatonin exacerbates acute experimental autoimmune encephalomyelitis by enhancing the serum levels of lactate: A potential biomarker of multiple sclerosis progression.
Topics: Animals; Biomarkers; Disease Progression; Encephalomyelitis, Autoimmune, Experimental; Female; Lacti | 2017 |
Serum melatonin in juvenile rheumatoid arthritis: correlation with disease activity.
Topics: Adolescent; Arthritis, Juvenile; Child; Cross-Sectional Studies; Disease Progression; Female; Humans | 2007 |
Serum melatonin levels in adolescent idiopathic scoliosis prediction and prevention for curve progression--a prospective study.
Topics: Adolescent; Child; Circadian Rhythm; Disease Progression; Humans; Male; Melatonin; Predictive Value | 2009 |
Antioxidant enzymes and melatonin levels in patients with bronchial asthma and chronic obstructive pulmonary disease during stable and exacerbation periods.
Topics: Antioxidants; Asthma; Catalase; Disease Progression; Glutathione Peroxidase; Glutathione Reductase; | 2009 |
Delayed onset of the diurnal melatonin rise in patients with Huntington's disease.
Topics: Chronobiology Disorders; Circadian Rhythm; Disease Progression; Down-Regulation; Female; Humans; Hun | 2009 |
[The role of melatonin in the development of metabolic syndrome].
Topics: Aged; Aged, 80 and over; Aging; Circadian Rhythm; Disease Progression; Female; Humans; Male; Melaton | 2009 |
Complete objective response of oesophageal squamocellular carcinoma to biological treatment.
Topics: Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; | 2009 |
Headaches and pineal cysts.
Topics: Adult; Central Nervous System Cysts; Chronic Disease; Disease Progression; Gonadal Steroid Hormones; | 2010 |
Circadian rhythm sleep disorder, free-running type in a sighted male with severe depression, anxiety, and agoraphobia.
Topics: Aged; Agoraphobia; Anxiety Disorders; Combined Modality Therapy; Depressive Disorder; Disease Progre | 2011 |
Contralateral retinal dopamine decrease and melatonin increase in progression of hemiparkinsonium rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Disease Progression; | 2012 |
Melatonin decreases levels of S100β and NFΚB, increases levels of synaptophysin in a rat model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; CA3 Region, Hippocampal; Cell Count; Cerebral Cor | 2013 |
Does the pineal gland have a role in the psychological mechanisms involved in the progression of cancer?
Topics: Amygdala; Animals; Autonomic Nervous System; Depression; Disease Progression; Emotions; Hormones; Hu | 2002 |
A possible link between melatonin levels, stress and coronary heart disease.
Topics: Causality; Circadian Rhythm; Coronary Disease; Disease Progression; Humans; Inflammation; Interleuki | 2002 |
The effect of melatonin treatment regimen on mammary adenocarcinoma development in HER-2/neu transgenic mice.
Topics: Adenocarcinoma; Animals; Antioxidants; Disease Progression; Female; Homozygote; Mammary Neoplasms, E | 2003 |
Reduction of serum melatonin levels in HIV-1-infected individuals' parallel disease progression: correlation with serum interleukin-12 levels.
Topics: Analysis of Variance; Biomarkers; Case-Control Studies; CD4 Lymphocyte Count; CD4-CD8 Ratio; Disease | 2003 |
Benign multiple sclerosis is characterized by a stable neuroimmunologic network.
Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Disability Evaluation; Disease Progression; Female; Fo | 2004 |
The profile of melatonin production in tumour-bearing rats.
Topics: Animals; Carcinoma 256, Walker; Chromatography, High Pressure Liquid; Circadian Rhythm; Disease Prog | 2004 |
[Influence of melatonin, serotonin and gastrin on streaming of chronic gastritis at elderly patients].
Topics: Aged; Apoptosis; Chronic Disease; Disease Progression; Enterochromaffin Cells; Gastric Mucosa; Gastr | 2005 |
[On the role of melatonin in development of arterial hypertension in the elderly persons].
Topics: Aged; Circadian Rhythm; Disease Progression; Humans; Hypertension; Melatonin; Middle Aged | 2005 |
Increased susceptibility of low-density lipoprotein to ex vivo oxidation in mice transgenic for human apolipoprotein B treated with 1 melatonin-related compound is not associated with atherosclerosis progression.
Topics: Animals; Antioxidants; Aorta; Apolipoproteins B; Atherosclerosis; Benzamides; Cattle; Cell Survival; | 2005 |
Surgical pinealectomy accelerates intervertebral disc degeneration process in chicken.
Topics: Animals; Chickens; Denervation; Disease Models, Animal; Disease Progression; Female; Intervertebral | 2006 |
Inhibition of experimental proliferative vitreoretinopathy with protein kinase C inhibitor (chelerythrine chloride) and melatonin.
Topics: Alkaloids; Animals; Benzophenanthridines; Disease Models, Animal; Disease Progression; Drug Therapy, | 2006 |
Relationship between salivary melatonin and severity of periodontal disease.
Topics: Adolescent; Adult; Aged; Antioxidants; Disease Progression; Female; Free Radical Scavengers; Humans; | 2006 |
Effects of exogenous melatonin and circadian synchronization on tumor progression in melanoma-bearing C57BL6 mice.
Topics: Animals; Body Temperature; Circadian Rhythm; Disease Progression; Light; Male; Melanoma, Experimenta | 2008 |
Lithium chloride enhances survival of NZB/W lupus mice: influence of melatonin and timing of treatment.
Topics: Adjuvants, Immunologic; Aging; Animals; Antibodies, Antinuclear; Disease Progression; DNA, Single-St | 1995 |
Total 24-hour melatonin secretion in adolescent idiopathic scoliosis. A case-control study.
Topics: Adolescent; Case-Control Studies; Disease Progression; Female; Humans; Male; Melatonin; Pineal Gland | 1998 |
Melatonin administration in tumor-bearing mice (intact and pinealectomized) in relation to stress, zinc, thymulin and IL-2.
Topics: Animal Feed; Animals; Corticosterone; Disease Progression; Feces; Female; Interleukin-2; Lung Neopla | 1999 |
Dim light during darkness stimulates tumor progression by enhancing tumor fatty acid uptake and metabolism.
Topics: Animals; Cell Division; Darkness; Disease Progression; Light; Linoleic Acid; Linoleic Acids; Male; M | 1999 |
Preventive effect of melatonin on the progression of carbon tetrachloride-induced acute liver injury in rats.
Topics: Animals; Antioxidants; Carbon Tetrachloride Poisoning; Disease Progression; Lipid Peroxidation; Live | 1999 |
[Melatonin and serotonin in inflammatory colon diseases and colorectal neoplasms].
Topics: Adenocarcinoma; Adolescent; Adult; Aged; APUD Cells; Biomarkers, Tumor; Biopsy; Colitis; Colorectal | 2000 |
Cause of idiopathic scoliosis.
Topics: Adolescent; Adult; Aging; Antioxidants; Biomarkers; Child; Circadian Rhythm; Disease Progression; Hu | 2000 |