melatonin has been researched along with Diabetic Neuropathies in 11 studies
Diabetic Neuropathies: Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Melatonin was also well tolerated." | 3.01 | Adjuvant use of melatonin for relieving symptoms of painful diabetic neuropathy: results of a randomized, double-blinded, controlled trial. ( Mehrpooya, M; Mohammadi, Y; Sajedi, F; Shokri, M, 2021) |
| "Melatonin level was evaluated by measuring 24-hour urine 6-sulfatoxymelatonin levels." | 1.62 | Presence of Peripheral Neuropathy Does Not Affect Urine 6-Sulfatoxymelatonin Levels in Type 2 Diabetics. ( Cakin, S; Karakılıç, E; Kurt, K; Ocak, O, 2021) |
| "Melatonin dynamics were re-evaluated with respect to autonomic nervous system in diabetic patients with autonomic neuropathy who were diagnosed by the cardiovascular reflex tests, heart rate variability (HRV), and 24-hr blood pressure monitoring." | 1.33 | Melatonin levels decrease in type 2 diabetic patients with cardiac autonomic neuropathy. ( Aksoyek, S; Batur, MK; Deger, A; Erbas, B; Erbas, T; Kabakci, G; Koray, Z; Tutuncu, NB; Tutuncu, T; Yildirir, A, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 5 (45.45) | 2.80 |
| Authors | Studies |
|---|---|
| Oliveira-Abreu, K | 1 |
| Cipolla-Neto, J | 1 |
| Leal-Cardoso, JH | 1 |
| Ocak, Ö | 2 |
| Silan, F | 1 |
| Şahin, EM | 1 |
| Che, H | 1 |
| Li, H | 1 |
| Li, Y | 1 |
| Wang, YQ | 1 |
| Yang, ZY | 1 |
| Wang, RL | 1 |
| Wang, LH | 1 |
| Kurt, K | 1 |
| Karakılıç, E | 1 |
| Cakin, S | 1 |
| Shokri, M | 1 |
| Sajedi, F | 1 |
| Mohammadi, Y | 1 |
| Mehrpooya, M | 1 |
| Gurel-Gokmen, B | 1 |
| Ipekci, H | 1 |
| Oktay, S | 1 |
| Alev, B | 1 |
| Ustundag, UV | 1 |
| Ak, E | 1 |
| Akakın, D | 1 |
| Sener, G | 1 |
| Emekli-Alturfan, E | 1 |
| Yarat, A | 1 |
| Tunali-Akbay, T | 1 |
| Seyit, DA | 1 |
| Degirmenci, E | 1 |
| Oguzhanoglu, A | 1 |
| Negi, G | 2 |
| Kumar, A | 2 |
| Kaundal, RK | 1 |
| Gulati, A | 1 |
| Sharma, SS | 2 |
| Tutuncu, NB | 1 |
| Batur, MK | 1 |
| Yildirir, A | 1 |
| Tutuncu, T | 1 |
| Deger, A | 1 |
| Koray, Z | 1 |
| Erbas, B | 1 |
| Kabakci, G | 1 |
| Aksoyek, S | 1 |
| Erbas, T | 1 |
| O'Brien, IA | 1 |
| Lewin, IG | 1 |
| O'Hare, JP | 1 |
| Arendt, J | 1 |
| Corrall, RJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Association Between Plasma Melatonin and No-reflow[NCT03306303] | 1,700 participants (Actual) | Observational | 2014-01-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for melatonin and Diabetic Neuropathies
| Article | Year |
|---|---|
Effects of Melatonin on Diabetic Neuropathy and Retinopathy.
Topics: Animals; Diabetes Complications; Diabetes Mellitus; Diabetic Neuropathies; Diabetic Retinopathy; Hum | 2021 |
1 trial available for melatonin and Diabetic Neuropathies
| Article | Year |
|---|---|
Adjuvant use of melatonin for relieving symptoms of painful diabetic neuropathy: results of a randomized, double-blinded, controlled trial.
Topics: Aged; Analgesics; Central Nervous System Depressants; Comorbidity; Diabetes Mellitus, Type 2; Diabet | 2021 |
9 other studies available for melatonin and Diabetic Neuropathies
| Article | Year |
|---|---|
Melatonin receptor gene polymorphisms as a risk factor in patients with diabetic peripheral neuropathy.
Topics: Diabetes Mellitus; Diabetic Neuropathies; Genetic Predisposition to Disease; Humans; Melatonin; Poly | 2022 |
Melatonin exerts neuroprotective effects by inhibiting neuronal pyroptosis and autophagy in STZ-induced diabetic mice.
Topics: Animals; Antioxidants; Autophagy; Autophagy-Related Protein 12; Beclin-1; Brain; Caspase 1; Cell Lin | 2020 |
Presence of Peripheral Neuropathy Does Not Affect Urine 6-Sulfatoxymelatonin Levels in Type 2 Diabetics.
Topics: Diabetes Mellitus, Type 2; Diabetic Neuropathies; Humans; Melatonin; Oxidative Stress | 2021 |
Melatonin improves hyperglycemia induced damages in rat brain.
Topics: Animals; Antioxidants; Brain; Brain Diseases, Metabolic; Diabetes Mellitus, Experimental; Diabetic N | 2018 |
Evaluation of Electrophysiological Effects of Melatonin and Alpha Lipoic Acid in Rats with Streptozotocine Induced Diabetic Neuropathy.
Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Diabetic Neuropathies; Disease Models, Animal; E | 2016 |
Functional and biochemical evidence indicating beneficial effect of Melatonin and Nicotinamide alone and in combination in experimental diabetic neuropathy.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Diabetic Neuropathies; Disease Models, Animal; Do | 2010 |
Melatonin modulates neuroinflammation and oxidative stress in experimental diabetic neuropathy: effects on NF-κB and Nrf2 cascades.
Topics: Animals; Blotting, Western; Cyclooxygenase 2; Diabetic Neuropathies; Immunohistochemistry; In Situ N | 2011 |
Melatonin levels decrease in type 2 diabetic patients with cardiac autonomic neuropathy.
Topics: Autonomic Nervous System Diseases; Blood Pressure; Circadian Rhythm; Diabetes Mellitus, Type 2; Diab | 2005 |
Abnormal circadian rhythm of melatonin in diabetic autonomic neuropathy.
Topics: Aged; Autonomic Nervous System Diseases; Blood Glucose; Circadian Rhythm; Diabetes Mellitus; Diabeti | 1986 |