melatonin has been researched along with Dementia, Vascular in 6 studies
Dementia, Vascular: An imprecise term referring to dementia associated with CEREBROVASCULAR DISORDERS, including CEREBRAL INFARCTION (single or multiple), and conditions associated with chronic BRAIN ISCHEMIA. Diffuse, cortical, and subcortical subtypes have been described. (From Gerontol Geriatr 1998 Feb;31(1):36-44)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The current review aims to examine melatonin therapy for both sleep disturbances and cognitive function in dementia." | 8.91 | Melatonin for sleep disorders and cognition in dementia: a meta-analysis of randomized controlled trials. ( Chen, SD; Dammer, EB; Li, CB; Wang, G; Wang, LL; Xu, G; Xu, J, 2015) |
| "Neurodegenerative diseases are the second most common cause of death and characterized by progressive impairments in movement or mental functioning in the central or peripheral nervous system." | 6.66 | Cellular Mechanisms of Melatonin: Insight from Neurodegenerative Diseases. ( Chen, D; Lee, TH; Zhang, T, 2020) |
| "The current review aims to examine melatonin therapy for both sleep disturbances and cognitive function in dementia." | 4.91 | Melatonin for sleep disorders and cognition in dementia: a meta-analysis of randomized controlled trials. ( Chen, SD; Dammer, EB; Li, CB; Wang, G; Wang, LL; Xu, G; Xu, J, 2015) |
| "Neurodegenerative diseases are the second most common cause of death and characterized by progressive impairments in movement or mental functioning in the central or peripheral nervous system." | 2.66 | Cellular Mechanisms of Melatonin: Insight from Neurodegenerative Diseases. ( Chen, D; Lee, TH; Zhang, T, 2020) |
| "Treatment with melatonin significantly increased OPN and SMP30 expression and ACh, NE, and Dop levels in the hippocampus with amelioration of the oxidative stress compared with BCCAO rats." | 1.48 | Melatonin ameliorates brain oxidative stress and upregulates senescence marker protein-30 and osteopontin in a rat model of vascular dementia. ( Bin-Jaliah, I; Sakr, HF, 2018) |
| "Thirteen elderly IPs with vascular dementia (mean age 76." | 1.33 | Passive body heating ameliorates sleep disturbances in patients with vascular dementia without circadian phase-shifting. ( Hishikawa, Y; Hozumi, S; Mishima, K; Mishima, Y; Shimizu, T, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Thangwong, P | 1 |
| Jearjaroen, P | 1 |
| Tocharus, C | 1 |
| Govitrapong, P | 1 |
| Tocharus, J | 1 |
| Chen, D | 1 |
| Zhang, T | 1 |
| Lee, TH | 1 |
| Shen, D | 1 |
| Tian, X | 1 |
| Sang, W | 1 |
| Song, R | 1 |
| Bin-Jaliah, I | 1 |
| Sakr, HF | 1 |
| Xu, J | 1 |
| Wang, LL | 1 |
| Dammer, EB | 1 |
| Li, CB | 1 |
| Xu, G | 1 |
| Chen, SD | 1 |
| Wang, G | 1 |
| Mishima, Y | 1 |
| Hozumi, S | 1 |
| Shimizu, T | 1 |
| Hishikawa, Y | 1 |
| Mishima, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Placebo-controlled Trial Evaluating the Effect of Melatonin on Sleep Quality in Patients With Dementia[NCT03066518] | Phase 4 | 40 participants (Actual) | Interventional | 2016-01-15 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for melatonin and Dementia, Vascular
| Article | Year |
|---|---|
Cellular Mechanisms of Melatonin: Insight from Neurodegenerative Diseases.
Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Circadian Rhythm; Dementia, Vascular; Hum | 2020 |
Melatonin for sleep disorders and cognition in dementia: a meta-analysis of randomized controlled trials.
Topics: Alzheimer Disease; Central Nervous System Depressants; Cognition; Cognition Disorders; Dementia; Dem | 2015 |
4 other studies available for melatonin and Dementia, Vascular
| Article | Year |
|---|---|
Melatonin suppresses inflammation and blood‒brain barrier disruption in rats with vascular dementia possibly by activating the SIRT1/PGC-1α/PPARγ signaling pathway.
Topics: Animals; Blood-Brain Barrier; Dementia, Vascular; Inflammation; Male; Melatonin; PPAR gamma; Rats; R | 2023 |
Effect of Melatonin and Resveratrol against Memory Impairment and Hippocampal Damage in a Rat Model of Vascular Dementia.
Topics: Animals; Antioxidants; Brain-Derived Neurotrophic Factor; Dementia, Vascular; Disease Models, Animal | 2016 |
Melatonin ameliorates brain oxidative stress and upregulates senescence marker protein-30 and osteopontin in a rat model of vascular dementia.
Topics: Acetylcholine; Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Calcium-Binding Protein | 2018 |
Passive body heating ameliorates sleep disturbances in patients with vascular dementia without circadian phase-shifting.
Topics: Aged; Body Temperature Regulation; Circadian Rhythm; Dementia, Vascular; Female; Heating; Humans; Im | 2005 |