Page last updated: 2024-10-19

melatonin and Delayed Effects, Prenatal Exposure

melatonin has been researched along with Delayed Effects, Prenatal Exposure in 69 studies

Research Excerpts

ExcerptRelevanceReference
"The aim of this review is to clarify the interrelationship between melatonin and autism spectrum disorder (ASD) during fetal development."8.98The Relationship between Autism Spectrum Disorder and Melatonin during Fetal Development. ( Choi, J; Hong, Y; Jin, Y; Won, J, 2018)
"C57BL/6 females were fed with a control (C) or a high-fat (HF) diet and supplemented with melatonin (Mel) during the pregnancy and lactation, forming the groups: C, CMel, HF, and HFMel."8.31Adult mice offspring of obese mothers supplemented with melatonin show lessened liver steatosis, inflammation, oxidative stress, and endoplasmic reticulum stress. ( Aguila, MB; Ajackson, M; Mandarim-de-Lacerda, CA; Marcondes-de-Castro, IA; Nagagata, BA, 2023)
"Hypertension can originate from early-life insults, whereas maternal melatonin therapy can be protective in a variety of models of programmed hypertension."7.85Maternal melatonin or agomelatine therapy prevents programmed hypertension in male offspring of mother exposed to continuous light. ( Chan, JYH; Hsu, CN; Lee, CT; Lin, YJ; Tain, YL, 2017)
"These results indicate that prophylactic administration of melatonin to the mother throughout pregnancy may prevent I/R-induced oxidative brain damage in neonatal rats."7.78Prophylactic administration of melatonin to the mother throughout pregnancy can protect against oxidative cerebral damage in neonatal rats. ( Fukaya, T; Hamada, F; Hayashi, Y; Imamura, R; Nagai, R; Shinohara, K; Wakatsuki, A; Watanabe, K, 2012)
"In this study, rats were randomly divided into four groups (ten animals each): intact control group, epilepsy control group, surgical pinealectomy + epilepsy group, and group with melatonin treatment following pinealectomy procedure."7.73Pinealectomy stimulates and exogenous melatonin inhibits harmful effects of epileptiform activity during pregnancy in the hippocampus of newborn rats: an immunohistochemical study. ( Ateş, U; Baka, M; Turgut, M; Uyanikgil, Y; Yurtseven, ME, 2006)
"The aim of the present study was to test the hypothesis that the natural antioxidant melatonin (MEL) and the synthetic antioxidant stobadine (STO) could reduce the incidence of maternal and embryofoetal toxicity in rats due to intrauterine hypoxia."7.72Effect of melatonin and stobadine on maternal and embryofoetal toxicity in rats due to intrauterine hypoxia induced by phenytoin administration. ( Brucknerová, I; Dubovický, M; Juránek, I; Mach, M; Navarová, J; Soltés, L; Ujházy, E; Zeman, M, 2004)
"The influence of pineal gland function and of melatonin during pregnancy upon sexual maturation of female offspring in rats was examined."7.68Melatonin administration during pregnancy retards sexual maturation of female offspring in the rat. ( Colmenero, MD; Díaz, B; Esquifino, A; González, ML; Marín, B; Miguel, JL, 1991)
"Low melatonin levels are a frequent finding in ASD patients."5.48Low maternal melatonin level increases autism spectrum disorder risk in children. ( Braam, W; Curfs, L; Ehrhart, F; Maas, APHM; Smits, MG, 2018)
" We examined whether maternal melatonin therapy can prevent maternal high-fructose combined with post-weaning high-salt diet-induced programmed hypertension in adult offspring."5.48Maternal Melatonin Therapy Attenuated Maternal High-Fructose Combined with Post-Weaning High-Salt Diets-Induced Hypertension in Adult Male Rat Offspring. ( Chan, JYH; Lee, WC; Leu, S; Tain, YL; Wu, KLH, 2018)
"Melatonin is a powerful antioxidant that can act as a protective agent against DNA damage caused by genotoxic agents, such as ethanol."5.48Protective effect of exogenous melatonin in rats and their offspring on the genotoxic response induced by the chronic consumption of alcohol during pregnancy. ( Chagas, CA; Lapa Neto, CJC; Santos, KRPD; Silva, MAD; Sousa Coelho, IDD; Souza, TGDS; Teixeira, ÁAC; Wanderley Teixeira, V, 2018)
"Melatonin was administered in drinking water (0."5.43Postnatal dexamethasone-induced programmed hypertension is related to the regulation of melatonin and its receptors. ( Chang, HY; Tain, YL, 2016)
"Melatonin (5 mg/kg) was administered i."5.43Melatonin modulates neonatal brain inflammation through endoplasmic reticulum stress, autophagy, and miR-34a/silent information regulator 1 pathway. ( Albertini, MC; Balduini, W; Buonocore, G; Carloni, S; Chalon, S; Favrais, G; Gressens, P; Longini, M; Saliba, E, 2016)
"The aim of this review is to clarify the interrelationship between melatonin and autism spectrum disorder (ASD) during fetal development."4.98The Relationship between Autism Spectrum Disorder and Melatonin during Fetal Development. ( Choi, J; Hong, Y; Jin, Y; Won, J, 2018)
"Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy."4.40Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023)
"C57BL/6 females were fed with a control (C) or a high-fat (HF) diet and supplemented with melatonin (Mel) during the pregnancy and lactation, forming the groups: C, CMel, HF, and HFMel."4.31Adult mice offspring of obese mothers supplemented with melatonin show lessened liver steatosis, inflammation, oxidative stress, and endoplasmic reticulum stress. ( Aguila, MB; Ajackson, M; Mandarim-de-Lacerda, CA; Marcondes-de-Castro, IA; Nagagata, BA, 2023)
"We investigated the effects of melatonin on rats with induced hypothyroidism during gestation as well as its effect on the development of the gonads of their offspring."3.96Effect of melatonin on gonad and thyroid development of offspring of hypothyroid pregnant rats. ( Alves, RDC; Baptista, MGP; D Assunção, CG; de Albuquerque, YML; Ferreira, CGM; Teixeira, ÁAC; Wanderley Teixeira, V, 2020)
"Several novel animal studies have shown that intrauterine metabolic programming can be modified in the event of reduced melatonin synthesis during pregnancy, leading to glucose intolerance and insulin resistance in the offspring."3.91Reduced melatonin synthesis in pregnant night workers: Metabolic implications for offspring. ( Amaral, F; Cipolla-Neto, J; Lowden, A; Moreno, CRC; Nehme, PA; Skene, DJ, 2019)
"Hypertension can originate from early-life insults, whereas maternal melatonin therapy can be protective in a variety of models of programmed hypertension."3.85Maternal melatonin or agomelatine therapy prevents programmed hypertension in male offspring of mother exposed to continuous light. ( Chan, JYH; Hsu, CN; Lee, CT; Lin, YJ; Tain, YL, 2017)
"Our results indicated that antioxidant therapy, by melatonin or N-acetylcysteine, in pregnant rats with nitric oxide deficiency can prevent programmed hypertension in male adult offspring."3.83Maternal melatonin or N-acetylcysteine therapy regulates hydrogen sulfide-generating pathway and renal transcriptome to prevent prenatal N ( Chan, JY; Hsu, CN; Lee, CT; Tain, YL, 2016)
"These results indicate that prophylactic administration of melatonin to the mother throughout pregnancy may prevent I/R-induced oxidative brain damage in neonatal rats."3.78Prophylactic administration of melatonin to the mother throughout pregnancy can protect against oxidative cerebral damage in neonatal rats. ( Fukaya, T; Hamada, F; Hayashi, Y; Imamura, R; Nagai, R; Shinohara, K; Wakatsuki, A; Watanabe, K, 2012)
"The effect of pinealectomy (PIN-X) and PIN-X+melatonin treatment during pregnancy (PIN-X+MEL) 100μg/100g body weight on Substance P (SP) in the striatum was investigated in offspring female rats."3.77Seasonal variations of Substance P in the striatum of the female rat are affected by maternal and offspring pinealectomy. ( Debeljuk, L; Díaz, B; Díaz, E; Durand, D; Fernández, C; Lasaga, M; Vázquez, N, 2011)
"In this study, rats were randomly divided into four groups (ten animals each): intact control group, epilepsy control group, surgical pinealectomy + epilepsy group, and group with melatonin treatment following pinealectomy procedure."3.73Pinealectomy stimulates and exogenous melatonin inhibits harmful effects of epileptiform activity during pregnancy in the hippocampus of newborn rats: an immunohistochemical study. ( Ateş, U; Baka, M; Turgut, M; Uyanikgil, Y; Yurtseven, ME, 2006)
"The aim of the present study was to test the hypothesis that the natural antioxidant melatonin (MEL) and the synthetic antioxidant stobadine (STO) could reduce the incidence of maternal and embryofoetal toxicity in rats due to intrauterine hypoxia."3.72Effect of melatonin and stobadine on maternal and embryofoetal toxicity in rats due to intrauterine hypoxia induced by phenytoin administration. ( Brucknerová, I; Dubovický, M; Juránek, I; Mach, M; Navarová, J; Soltés, L; Ujházy, E; Zeman, M, 2004)
"We evaluated whether melatonin administration to pregnant rats during the final week of pregnancy affects prepubertal secretion of luteinizing hormone (LH), follicle stimulating hormone (FSH), and prolactin in offspring."3.71Effect of prenatal melatonin exposure on gonadotropins and prolactin secretion in male and female rat pups. ( Miyahara, Y; Okatani, Y; Otukonyong, EE; Wakatsuki, A, 2001)
"Three groups of female Wistar rats were used: control, PIN-X, and those treated (250 micrograms/100 g body weight) with melatonin throughout pregnancy."3.69Maternal pineal gland participates in prepubertal rats' ovarian oocyte development. ( Colmenero, MD; Díaz, B; Díaz, E; Fernández, B, 1995)
"The influence of pineal gland function and of melatonin during pregnancy upon sexual maturation of female offspring in rats was examined."3.68Melatonin administration during pregnancy retards sexual maturation of female offspring in the rat. ( Colmenero, MD; Díaz, B; Esquifino, A; González, ML; Marín, B; Miguel, JL, 1991)
" This review details the adverse effects of IUGR on fetal brain development and discusses intervention strategies."2.53Neurodevelopment in children with intrauterine growth restriction: adverse effects and interventions. ( Fu, W; Liu, J; Wang, Y, 2016)
"Melatonin treatment, however, improved their nursing behaviour and reduced their plasma corticosterone levels."1.91Postnatal melatonin administration to stressed dams for ameliorating risk-taking behaviour in rat pups through maternal care improvement. ( Bagheri, F; Goudarzi, I, 2023)
"Melatonin (Mel) has strong antioxidant properties since it is a direct scavenger of oxygen-based free radicals and related species."1.48The neuroprotective effect of melatonin on the hippocampus exposed to diclofenac sodium during the prenatal period. ( Kaplan, S; Kıvrak, EG; Yurt, KK, 2018)
"Low melatonin levels are a frequent finding in ASD patients."1.48Low maternal melatonin level increases autism spectrum disorder risk in children. ( Braam, W; Curfs, L; Ehrhart, F; Maas, APHM; Smits, MG, 2018)
"Melatonin was intraperitoneally injected at a dose of 10 mg/kg daily (from E15 until delivery of from E6 for 20 days after delivery)."1.48Therapeutic effect of perinatal exogenous melatonin on behavioral and histopathological changes and antioxidative enzymes in neonate mouse model of cortical malformation. ( Azizi, M; Kashani, IR; Mokhtari, T; Nadji, SA; Omidi, N; Pasbakhsh, P; Pourabdollah, M; Sadr, M; Zendehdel, A, 2018)
" We examined whether maternal melatonin therapy can prevent maternal high-fructose combined with post-weaning high-salt diet-induced programmed hypertension in adult offspring."1.48Maternal Melatonin Therapy Attenuated Maternal High-Fructose Combined with Post-Weaning High-Salt Diets-Induced Hypertension in Adult Male Rat Offspring. ( Chan, JYH; Lee, WC; Leu, S; Tain, YL; Wu, KLH, 2018)
"Melatonin is a powerful antioxidant that can act as a protective agent against DNA damage caused by genotoxic agents, such as ethanol."1.48Protective effect of exogenous melatonin in rats and their offspring on the genotoxic response induced by the chronic consumption of alcohol during pregnancy. ( Chagas, CA; Lapa Neto, CJC; Santos, KRPD; Silva, MAD; Sousa Coelho, IDD; Souza, TGDS; Teixeira, ÁAC; Wanderley Teixeira, V, 2018)
"Melatonin was administered in drinking water (0."1.43Postnatal dexamethasone-induced programmed hypertension is related to the regulation of melatonin and its receptors. ( Chang, HY; Tain, YL, 2016)
"Melatonin (5 mg/kg) was administered i."1.43Melatonin modulates neonatal brain inflammation through endoplasmic reticulum stress, autophagy, and miR-34a/silent information regulator 1 pathway. ( Albertini, MC; Balduini, W; Buonocore, G; Carloni, S; Chalon, S; Favrais, G; Gressens, P; Longini, M; Saliba, E, 2016)
"Melatonin (10mg/kg) was given once daily at the same time."1.42Melatonin ameliorates oxidative damage induced by maternal lead exposure in rat pups. ( Bazrgar, M; Elahdadi Salmani, M; Goudarzi, I; Lashkarbolouki, T, 2015)
"Melatonin has been shown to have beneficial effects in compromised pregnancies."1.42Effects of melatonin on prenatal dexamethasone-induced epigenetic alterations in hippocampal morphology and reelin and glutamic acid decarboxylase 67 levels. ( Chang, KA; Chen, CC; Hsu, MH; Huang, LT; Kuo, HC; Lui, CC; Sheen, JM; Tain, YL; Tiao, MM; Yu, HR, 2015)
"Food intake and weight gain are known to be affected by stress."1.36The weight gain response to stress during adulthood is conditioned by both sex and prenatal stress exposure. ( Argente, J; Azcoitia, I; Calmarza-Font, I; Chowen, JA; Diz-Chaves, Y; Frago, LM; García-Cáceres, C; Garcia-Segura, LM; Lagunas, N, 2010)
"When melatonin was given to the mothers instead of the endogenous pineal secretory activity for 5 days during the late period of gestation, this treatment reversed the effects of maternal ganglionectomy and pinealectomy."1.33Pup circadian rhythm entrainment--effect of maternal ganglionectomy or pinealectomy. ( Bellavía, SL; Carpentieri, AR; Macchione, AF; Vaqué, AM; Vermouth, NT, 2006)

Research

Studies (69)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.45)18.7374
1990's5 (7.25)18.2507
2000's17 (24.64)29.6817
2010's39 (56.52)24.3611
2020's7 (10.14)2.80

Authors

AuthorsStudies
Ajackson, M2
Nagagata, BA2
Marcondes-de-Castro, IA2
Mandarim-de-Lacerda, CA2
Aguila, MB2
Bagheri, F2
Goudarzi, I3
Nehme, PA1
Amaral, F1
Lowden, A1
Skene, DJ1
Cipolla-Neto, J2
Moreno, CRC1
de Albuquerque, YML1
Ferreira, CGM1
D Assunção, CG1
Baptista, MGP1
Alves, RDC1
Wanderley Teixeira, V2
Teixeira, ÁAC2
Hsu, CN5
Tain, YL10
Abdel-Wahab, A1
Hassanin, KMA1
Ibrahim, SS1
El-Kossi, DMMH1
Abdel-Razik, AH1
Alves, CDS1
Frias, HV1
Bonamin, LV1
Correia, MSF1
Corrêa, MG1
Bondan, EF1
de Fátima M Martins, M1
Coelho, CP1
Bernardi, MM1
Suffredini, IB1
Arutyunyan, AV1
Zaloznyaya, IV1
Kerkeshko, GO1
Milyutina, YP1
Korenevskii, AV1
Yurt, KK2
Kaplan, S4
Kıvrak, EG2
Lin, YJ1
Chan, JYH2
Lee, CT3
Jin, Y1
Choi, J1
Won, J1
Hong, Y1
Braam, W1
Ehrhart, F1
Maas, APHM1
Smits, MG1
Curfs, L1
Azizi, M1
Pasbakhsh, P1
Nadji, SA1
Pourabdollah, M1
Mokhtari, T1
Sadr, M1
Omidi, N1
Kashani, IR1
Zendehdel, A1
Leu, S1
Lee, WC1
Wu, KLH1
Sousa Coelho, IDD1
Lapa Neto, CJC1
Souza, TGDS1
Silva, MAD1
Chagas, CA1
Santos, KRPD1
Motta-Teixeira, LC1
Machado-Nils, AV1
Battagello, DS1
Diniz, GB1
Andrade-Silva, J1
Silva, S1
Matos, RA1
do Amaral, FG1
Xavier, GF1
Bittencourt, JC1
Reiter, RJ1
Lucassen, PJ1
Korosi, A1
McCarty, KJ1
Owen, MPT1
Hart, CG2
Thompson, RC1
Burnett, DD1
King, EH1
Hopper, RM1
Lemley, CO3
Aubrecht, TG1
Weil, ZM1
Nelson, RJ1
Marzullo, G1
Vilches, N1
Spichiger, C2
Mendez, N2
Abarzua-Catalan, L1
Galdames, HA1
Hazlerigg, DG1
Richter, HG2
Torres-Farfan, C2
Chen, CC3
Sheen, JM3
Yu, HR3
Tiao, MM3
Kuo, HC3
Huang, LT5
Chen, CJ1
Huang, YH1
Tang, KS1
Chu, EW1
Keskin, I1
Kalkan, S1
Sutcu, M1
Ulkay, MB1
Esener, OB1
Lui, CC1
Hsu, MH1
Chang, KA1
Wang, Y1
Fu, W1
Liu, J1
Lashkarbolouki, T2
Elahdadi Salmani, M2
Bazrgar, M1
Khoshvakhti, H1
Altunkaynak, BZ1
Türkmen, AP1
Elibol, E1
Aydın, I2
Önger, ME1
Keomanivong, FE1
Camacho, LE1
Yunusova, R1
Borowicz, PP1
Caton, JS1
Meyer, AM1
Vonnahme, KA1
Swanson, KC1
Brockus, KE1
Fleming, BO1
Smith, T1
Ward, SH1
Chang, HY1
Gao, L1
Zhao, YC1
Liang, Y1
Lin, XH1
Tan, YJ1
Wu, DD1
Li, XZ1
Ye, BZ1
Kong, FQ1
Sheng, JZ1
Huang, HF1
Carloni, S1
Favrais, G1
Saliba, E1
Albertini, MC1
Chalon, S1
Longini, M1
Gressens, P1
Buonocore, G1
Balduini, W1
Erdem Koç, G1
Altun, G1
Gümüş, H1
Gülsüm Deniz, Ö1
Emin Onger, M1
Altunkaynak, Z1
Chan, JY1
Voiculescu, SE1
Le Duc, D1
Roșca, AE1
Zeca, V1
Chiţimuș, DM1
Arsene, AL1
Drăgoi, CM1
Nicolae, AC1
Zăgrean, L1
Schöneberg, T1
Zăgrean, AM1
Halabi, D1
Salazar, ER1
Vergara, K1
Alonso-Vasquez, P1
Carmona, P1
Sarmiento, JM1
Seron-Ferre, M1
Baykan, A1
Narin, N1
Narin, F1
Akgün, H1
Yavaşcan, S1
Saraymen, R1
Kaewsuk, S1
Sae-ung, K1
Phansuwan-Pujito, P1
Govitrapong, P1
Sheth, DS1
Tajuddin, NF1
Druse, MJ1
Hutton, LC1
Abbass, M1
Dickinson, H1
Ireland, Z1
Walker, DW1
García-Cáceres, C1
Diz-Chaves, Y1
Lagunas, N1
Calmarza-Font, I1
Azcoitia, I1
Garcia-Segura, LM1
Frago, LM1
Argente, J1
Chowen, JA1
Anderson, G1
Díaz, E3
Vázquez, N1
Fernández, C1
Durand, D1
Lasaga, M1
Debeljuk, L4
Díaz, B4
Singh, HJ1
Keah, LS1
Kumar, A1
Sirajudeen, KN1
Watanabe, K1
Hamada, F1
Wakatsuki, A2
Nagai, R1
Shinohara, K1
Hayashi, Y1
Imamura, R1
Fukaya, T1
Ma, N1
Hardy, DB1
Martinez-Cruz, F2
Pozo, D1
Osuna, C2
Espinar, A1
Marchante, C1
Guerrero, JM2
Kennaway, DJ1
Dubovický, M2
Ujházy, E2
Kovacovský, P1
Navarová, J2
Juráni, M1
Soltés, L2
Mach, M1
Juránek, I1
Brucknerová, I1
Zeman, M1
Tuthill, CR2
Freeman, DA1
Butler, MP1
Chinn, T1
Park, JH1
Zucker, I2
Turgut, M2
Uyanikgil, Y2
Ateş, U2
Baka, M2
Yurtseven, ME2
Bellavía, SL1
Carpentieri, AR1
Vaqué, AM1
Macchione, AF1
Vermouth, NT1
Yavaşoğlu, A1
Ulker, S1
Sözmen, EY1
Sezer, E1
Elmas, C1
Shang, EH1
Zhdanova, IV1
Fernández, B1
Colmenero, MD2
Díaz Rodríguez, E2
Esquifino, A3
Marín, B2
Díaz López, B2
Esquifino Parras, AI1
Arce Fraguas, A1
Marín Fernández, B1
Arce, A1
Okatani, Y1
Otukonyong, EE1
Miyahara, Y1
Kim, CY1
Lee, BN1
Kim, JS1
Miguel, JL1
González, ML1
Horton, TH1
Stetson, MH1
Lee, TM1
Spears, N1

Reviews

8 reviews available for melatonin and Delayed Effects, Prenatal Exposure

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Light and Circadian Signaling Pathway in Pregnancy: Programming of Adult Health and Disease.
    International journal of molecular sciences, 2020, Mar-23, Volume: 21, Issue:6

    Topics: Animals; Circadian Clocks; Circadian Rhythm; Disease Susceptibility; Embryonic Development; Female;

2020
The Relationship between Autism Spectrum Disorder and Melatonin during Fetal Development.
    Molecules (Basel, Switzerland), 2018, Jan-18, Volume: 23, Issue:1

    Topics: Animals; Autism Spectrum Disorder; Circadian Rhythm; Female; Fetal Development; Humans; Maternal Exp

2018
Neurodevelopment in children with intrauterine growth restriction: adverse effects and interventions.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2016, Volume: 29, Issue:4

    Topics: Adult; Antioxidants; Brain; Cerebral Palsy; Child; Cognition Disorders; Depression; Developmental Di

2016
Developmental Programming of Adult Disease: Reprogramming by Melatonin?
    International journal of molecular sciences, 2017, Feb-16, Volume: 18, Issue:2

    Topics: Adult; Animals; Disease Susceptibility; Female; Fetal Development; Humans; Melatonin; Models, Animal

2017
The fetal origins of the metabolic syndrome: can we intervene?
    Journal of pregnancy, 2012, Volume: 2012

    Topics: Antioxidants; Ascorbic Acid; Diet Therapy; Dietary Supplements; Exenatide; Fatty Acids, Omega-3; Fem

2012
Programming of the fetal suprachiasmatic nucleus and subsequent adult rhythmicity.
    Trends in endocrinology and metabolism: TEM, 2002, Volume: 13, Issue:9

    Topics: Animals; Birth Weight; Body Height; Circadian Rhythm; Drug-Related Side Effects and Adverse Reaction

2002
Maternal programming of the fetal brain dictates the response of juvenile Siberian hamsters to photoperiod: dissecting the information transfer system.
    The Journal of experimental zoology. Supplement : published under auspices of the American Society of Zoologists and the Division of Comparative Physiology and Biochemistry, 1990, Volume: 4

    Topics: Animals; Brain; Cricetinae; Female; Lighting; Male; Maternal-Fetal Exchange; Melatonin; Neurosecreto

1990

Trials

4 trials available for melatonin and Delayed Effects, Prenatal Exposure

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effect of chronic melatonin supplementation during mid to late gestation on maternal uterine artery blood flow and subsequent development of male offspring in beef cattle.
    Journal of animal science, 2018, Dec-03, Volume: 96, Issue:12

    Topics: Animals; Cattle; Dietary Supplements; Drug Implants; Female; Fetus; Male; Melatonin; Placenta; Pregn

2018
Influence of nutrient restriction and melatonin supplementation of pregnant ewes on maternal and fetal pancreatic digestive enzymes and insulin-containing clusters.
    Animal : an international journal of animal bioscience, 2016, Volume: 10, Issue:3

    Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Diet; Dietary Supplements; Female;

2016
Effects of Supplementing Holstein Heifers with Dietary Melatonin during Late Gestation on Growth and Cardiovascular Measurements of their Offspring.
    Reproduction in domestic animals = Zuchthygiene, 2016, Volume: 51, Issue:2

    Topics: Animal Nutritional Physiological Phenomena; Animals; Antioxidants; Blood Pressure; Cattle; Dietary S

2016

Other Studies

58 other studies available for melatonin and Delayed Effects, Prenatal Exposure

ArticleYear
Adult mice offspring of obese mothers supplemented with melatonin show lessened liver steatosis, inflammation, oxidative stress, and endoplasmic reticulum stress.
    Life sciences, 2023, Jan-01, Volume: 312

    Topics: AMP-Activated Protein Kinases; Animals; Diet, High-Fat; Dietary Supplements; Endoplasmic Reticulum S

2023
Adult mice offspring of obese mothers supplemented with melatonin show lessened liver steatosis, inflammation, oxidative stress, and endoplasmic reticulum stress.
    Life sciences, 2023, Jan-01, Volume: 312

    Topics: AMP-Activated Protein Kinases; Animals; Diet, High-Fat; Dietary Supplements; Endoplasmic Reticulum S

2023
Adult mice offspring of obese mothers supplemented with melatonin show lessened liver steatosis, inflammation, oxidative stress, and endoplasmic reticulum stress.
    Life sciences, 2023, Jan-01, Volume: 312

    Topics: AMP-Activated Protein Kinases; Animals; Diet, High-Fat; Dietary Supplements; Endoplasmic Reticulum S

2023
Adult mice offspring of obese mothers supplemented with melatonin show lessened liver steatosis, inflammation, oxidative stress, and endoplasmic reticulum stress.
    Life sciences, 2023, Jan-01, Volume: 312

    Topics: AMP-Activated Protein Kinases; Animals; Diet, High-Fat; Dietary Supplements; Endoplasmic Reticulum S

2023
Postnatal melatonin administration to stressed dams for ameliorating risk-taking behaviour in rat pups through maternal care improvement.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2023, Volume: 83, Issue:4

    Topics: Animals; Anxiety; Corticosterone; Female; Humans; Melatonin; Pregnancy; Prenatal Exposure Delayed Ef

2023
Reduced melatonin synthesis in pregnant night workers: Metabolic implications for offspring.
    Medical hypotheses, 2019, Volume: 132

    Topics: Circadian Rhythm; Energy Metabolism; Female; Fetus; Glucose Intolerance; Humans; Insulin Resistance;

2019
Effect of melatonin on gonad and thyroid development of offspring of hypothyroid pregnant rats.
    Biotechnic & histochemistry : official publication of the Biological Stain Commission, 2020, Volume: 95, Issue:7

    Topics: Animals; Antioxidants; Antithyroid Agents; Female; Gonads; Hypothyroidism; Melatonin; Pregnancy; Pre

2020
Developmental Programming: Physiological Impacts of Prenatal Melatonin Administration on Reproductive Capacity and Serum Triiodothyronine of Adult Female Offspring Rat Born to Moms Exposed to Bisphenol A During Pregnancy.
    Reproductive sciences (Thousand Oaks, Calif.), 2021, Volume: 28, Issue:7

    Topics: Animals; Benzhydryl Compounds; Female; Melatonin; Phenols; Pregnancy; Prenatal Exposure Delayed Effe

2021
Luffa operculata at a late period of gestation dysregulates melatonin and cytokines interfering with weight of dams and their male offspring.
    Journal of ethnopharmacology, 2021, Jul-15, Volume: 275

    Topics: Administration, Oral; Adrenocorticotropic Hormone; Animals; Animals, Newborn; Behavior, Animal; Body

2021
Prenatal Hyperhomocysteinemia Impairs Hypothalamic Regulation of Reproductive Cycles in Rat Progeny.
    Bulletin of experimental biology and medicine, 2017, Volume: 162, Issue:6

    Topics: Animals; Antioxidants; Arcuate Nucleus of Hypothalamus; Catecholamines; Estrous Cycle; Female; Gonad

2017
The neuroprotective effect of melatonin on the hippocampus exposed to diclofenac sodium during the prenatal period.
    Journal of chemical neuroanatomy, 2018, Volume: 87

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Diclofenac; Female; Hippocampus; Mal

2018
Maternal melatonin or agomelatine therapy prevents programmed hypertension in male offspring of mother exposed to continuous light.
    Biology of reproduction, 2017, Oct-01, Volume: 97, Issue:4

    Topics: Acetamides; Animals; Antioxidants; Female; Hypertension; Hypnotics and Sedatives; Light; Male; Mater

2017
Low maternal melatonin level increases autism spectrum disorder risk in children.
    Research in developmental disabilities, 2018, Volume: 82

    Topics: Adult; Autism Spectrum Disorder; Case-Control Studies; Child; Female; Gene-Environment Interaction;

2018
Therapeutic effect of perinatal exogenous melatonin on behavioral and histopathological changes and antioxidative enzymes in neonate mouse model of cortical malformation.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2018, Volume: 68

    Topics: Animals; Animals, Newborn; Antioxidants; Carcinogens; Catalase; Disease Models, Animal; Exploratory

2018
Maternal Melatonin Therapy Attenuated Maternal High-Fructose Combined with Post-Weaning High-Salt Diets-Induced Hypertension in Adult Male Rat Offspring.
    Molecules (Basel, Switzerland), 2018, Apr-11, Volume: 23, Issue:4

    Topics: Animals; Disease Models, Animal; Female; Fructose; Gene Expression Regulation; Hypertension; Male; M

2018
Protective effect of exogenous melatonin in rats and their offspring on the genotoxic response induced by the chronic consumption of alcohol during pregnancy.
    Mutation research. Genetic toxicology and environmental mutagenesis, 2018, Volume: 832-833

    Topics: Animals; Animals, Newborn; Brain; Central Nervous System Depressants; Comet Assay; DNA Damage; Ethan

2018
The absence of maternal pineal melatonin rhythm during pregnancy and lactation impairs offspring physical growth, neurodevelopment, and behavior.
    Hormones and behavior, 2018, Volume: 105

    Topics: Animals; Behavior, Animal; Circadian Rhythm; Cognition; Female; Growth and Development; Lactation; M

2018
Melatonin treatment during early life interacts with restraint to alter neuronal morphology and provoke depressive-like responses.
    Behavioural brain research, 2014, Apr-15, Volume: 263

    Topics: Anhedonia; Animals; Anxiety; CA1 Region, Hippocampal; Cricetinae; Dendrites; Depressive Disorder; Di

2014
Similar photoperiod-related birth seasonalities among professional baseball players and lesbian women with an opposite seasonality among gay men: Maternal melatonin may affect fetal sexual dimorphism.
    Psychiatry research, 2014, May-30, Volume: 216, Issue:3

    Topics: Age Factors; Athletes; Baseball; Brain; Europe; Female; Fetus; Gestational Age; Homosexuality, Femal

2014
Gestational chronodisruption impairs hippocampal expression of NMDA receptor subunits Grin1b/Grin3a and spatial memory in the adult offspring.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Animals; Circadian Clocks; Female; Gene Expression Regulation; Hippocampus; Light; Maternal Exposure

2014
Melatonin attenuates prenatal dexamethasone-induced blood pressure increase in a rat model.
    Journal of the American Society of Hypertension : JASH, 2014, Volume: 8, Issue:4

    Topics: Animals; Blotting, Western; Dexamethasone; Female; Histone Deacetylases; Hypertension; Maternal Expo

2014
Melatonin in the regulation of liver steatosis following prenatal glucocorticoid exposure.
    BioMed research international, 2014, Volume: 2014

    Topics: Animals; Apoptosis; Cytokines; Fatty Liver; Female; Glucocorticoids; Liver; Male; Melatonin; Pregnan

2014
Melatonin therapy prevents programmed hypertension and nitric oxide deficiency in offspring exposed to maternal caloric restriction.
    Oxidative medicine and cellular longevity, 2014, Volume: 2014

    Topics: Animals; Arginine; Caloric Restriction; Female; Hypertension; In Vitro Techniques; Kidney; Male; Mel

2014
Evaluation of neuroprotection by melatonin against adverse effects of prenatal exposure to a nonsteroidal anti-inflammatory drug during peripheral nerve development.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2015, Volume: 41

    Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroida

2015
Effects of melatonin on prenatal dexamethasone-induced epigenetic alterations in hippocampal morphology and reelin and glutamic acid decarboxylase 67 levels.
    Developmental neuroscience, 2015, Volume: 37, Issue:2

    Topics: Animals; Behavior, Animal; Cell Adhesion Molecules, Neuronal; Dexamethasone; DNA (Cytosine-5-)-Methy

2015
Melatonin prevents oxidative damage induced by maternal ethanol administration and reduces homocysteine in the cerebellum of rat pups.
    Behavioural brain research, 2015, Volume: 287

    Topics: Animals; bcl-2-Associated X Protein; Catalase; Central Nervous System Depressants; Cerebellum; Ethan

2015
Melatonin ameliorates oxidative damage induced by maternal lead exposure in rat pups.
    Physiology & behavior, 2015, Nov-01, Volume: 151

    Topics: Animals; Cerebellum; Female; Glutathione Peroxidase; Lead; Lipid Peroxidation; Maternal Exposure; Me

2015
Effects of melatonin on diclofenac sodium treated rat kidney: a stereological and histopathological study.
    Renal failure, 2015, Volume: 37, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Diclofenac; Female; Kidney Glomerulu

2015
Postnatal dexamethasone-induced programmed hypertension is related to the regulation of melatonin and its receptors.
    Steroids, 2016, Volume: 108

    Topics: Animals; Blood Pressure; Dexamethasone; Female; Gene Expression Regulation; Heart; Hypertension; Kid

2016
The impaired myocardial ischemic tolerance in adult offspring of diabetic pregnancy is restored by maternal melatonin treatment.
    Journal of pineal research, 2016, Volume: 61, Issue:3

    Topics: Animals; Apoptosis; Diabetes Mellitus, Experimental; Dietary Supplements; Female; Melatonin; Mice; M

2016
Melatonin modulates neonatal brain inflammation through endoplasmic reticulum stress, autophagy, and miR-34a/silent information regulator 1 pathway.
    Journal of pineal research, 2016, Volume: 61, Issue:3

    Topics: Animals; Animals, Newborn; Autophagy; Brain; Endoplasmic Reticulum Stress; Female; Inflammation; Lip

2016
Neuroprotective effects of melatonin and omega-3 on hippocampal cells prenatally exposed to 900 MHz electromagnetic fields.
    International journal of radiation biology, 2016, Volume: 92, Issue:10

    Topics: Animals; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electromagnetic Fi

2016
Maternal melatonin or N-acetylcysteine therapy regulates hydrogen sulfide-generating pathway and renal transcriptome to prevent prenatal N
    American journal of obstetrics and gynecology, 2016, Volume: 215, Issue:5

    Topics: Acetylcysteine; Administration, Oral; Animals; Antioxidants; Biomarkers; Female; Fetal Development;

2016
Behavioral and molecular effects of prenatal continuous light exposure in the adult rat.
    Brain research, 2016, 11-01, Volume: 1650

    Topics: Animals; Animals, Newborn; Anxiety; Behavior, Animal; Brain; Circadian Rhythm; Female; Light; Male;

2016
Gestational Chronodisruption Impairs Circadian Physiology in Rat Male Offspring, Increasing the Risk of Chronic Disease.
    Endocrinology, 2016, Volume: 157, Issue:12

    Topics: Aldosterone; Animals; Blood Pressure; Body Temperature; Chronic Disease; Circadian Rhythm; CLOCK Pro

2016
The protective effect of melatonin on nicotine-induced myocardial injury in newborn rats whose mothers received nicotine.
    Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2008, Volume: 8, Issue:4

    Topics: Animals; Animals, Newborn; Antioxidants; Dose-Response Relationship, Drug; Female; Glutathione Perox

2008
Melatonin attenuates methamphetamine-induced reduction of tyrosine hydroxylase, synaptophysin and growth-associated protein-43 levels in the neonatal rat brain.
    Neurochemistry international, 2009, Volume: 55, Issue:6

    Topics: Amphetamine-Related Disorders; Animals; Animals, Newborn; Antioxidants; Brain; Brain Chemistry; Cent

2009
Antioxidant neuroprotection against ethanol-induced apoptosis in HN2-5 cells.
    Brain research, 2009, Aug-18, Volume: 1285

    Topics: Acetylcysteine; Alcohol-Induced Disorders, Nervous System; Animals; Antioxidants; Apoptosis; Apoptos

2009
Neuroprotective properties of melatonin in a model of birth asphyxia in the spiny mouse (Acomys cahirinus).
    Developmental neuroscience, 2009, Volume: 31, Issue:5

    Topics: Analysis of Variance; Animals; Animals, Newborn; Apoptosis; Caspase 3; Cell Count; Cerebral Cortex;

2009
The weight gain response to stress during adulthood is conditioned by both sex and prenatal stress exposure.
    Psychoneuroendocrinology, 2010, Volume: 35, Issue:3

    Topics: Age Factors; Animals; Blood Glucose; Castration; Corticosterone; Eating; Female; Hormones; Male; Mel

2010
Prenatal corticosteroids: pretermer outcomes, stress, schizophrenia, multiple sclerosis and the developmental role of melatonin and vitamin D3.
    Journal of pediatric and adolescent gynecology, 2010, Volume: 23, Issue:5

    Topics: Cholecalciferol; Dietary Supplements; Female; Humans; Hydrocortisone; Infant, Newborn; Melatonin; Mu

2010
Seasonal variations of Substance P in the striatum of the female rat are affected by maternal and offspring pinealectomy.
    Neuroscience letters, 2011, Apr-01, Volume: 492, Issue:2

    Topics: Age Factors; Animals; Animals, Newborn; Corpus Striatum; Female; Gene Expression Regulation; Male; M

2011
Adverse effects of melatonin on rat pups of Wistar-Kyoto dams receiving melatonin supplementation during pregnancy.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2012, Volume: 64, Issue:7-8

    Topics: Administration, Oral; Animals; Animals, Newborn; Blood Pressure; Female; Maternal Exposure; Melatoni

2012
Prophylactic administration of melatonin to the mother throughout pregnancy can protect against oxidative cerebral damage in neonatal rats.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2012, Volume: 25, Issue:8

    Topics: Animals; Animals, Newborn; Antioxidants; Cerebrum; Chemoprevention; Cytoprotection; Drug Administrat

2012
Oxidative stress induced by phenylketonuria in the rat: Prevention by melatonin, vitamin E, and vitamin C.
    Journal of neuroscience research, 2002, Aug-15, Volume: 69, Issue:4

    Topics: Animals; Animals, Newborn; Antioxidants; Ascorbic Acid; Brain; Cerebellum; Disease Models, Animal; F

2002
Effect of melatonin on neurobehavioral dysfunctions induced by intrauterine hypoxia in rats.
    Central European journal of public health, 2004, Volume: 12 Suppl

    Topics: Analysis of Variance; Animals; Behavior, Animal; Female; Hypoxia; Melatonin; Oxidative Stress; Pheny

2004
Effect of melatonin and stobadine on maternal and embryofoetal toxicity in rats due to intrauterine hypoxia induced by phenytoin administration.
    Central European journal of public health, 2004, Volume: 12 Suppl

    Topics: Abnormalities, Drug-Induced; Analysis of Variance; Animals; Animals, Newborn; Anticonvulsants; Body

2004
Perinatal influences of melatonin on testicular development and photoperiodic memory in Siberian hamsters.
    Journal of neuroendocrinology, 2005, Volume: 17, Issue:8

    Topics: Age Factors; Animals; Animals, Newborn; Biological Clocks; Cricetinae; Female; Male; Melatonin; Phod

2005
Mitochondrial damage induced by fetal hyperphenylalaninemia in the rat brain and liver: its prevention by melatonin, Vitamin E, and Vitamin C.
    Neuroscience letters, 2006, Jan-09, Volume: 392, Issue:1-2

    Topics: Aldehydes; Animals; Animals, Newborn; Ascorbic Acid; Disease Models, Animal; Drug Interactions; Fema

2006
Pinealectomy stimulates and exogenous melatonin inhibits harmful effects of epileptiform activity during pregnancy in the hippocampus of newborn rats: an immunohistochemical study.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2006, Volume: 22, Issue:5

    Topics: Analysis of Variance; Animals; Animals, Newborn; Anticonvulsants; Epilepsy; Female; Gene Expression

2006
Pup circadian rhythm entrainment--effect of maternal ganglionectomy or pinealectomy.
    Physiology & behavior, 2006, Oct-30, Volume: 89, Issue:3

    Topics: Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Circadian Rhythm; Drinking Behavi

2006
Neuroprotective effects of melatonin upon the offspring cerebellar cortex in the rat model of BCNU-induced cortical dysplasia.
    Brain research, 2007, Jul-30, Volume: 1160

    Topics: Animals; Animals, Newborn; Brain Diseases; Bromodeoxyuridine; Carmustine; Cerebellar Cortex; Disease

2007
The circadian system is a target and modulator of prenatal cocaine effects.
    PloS one, 2007, Jul-11, Volume: 2, Issue:7

    Topics: Animals; Animals, Genetically Modified; Circadian Rhythm; Cocaine; Cocaine-Related Disorders; Embryo

2007
Maternal pineal gland participates in prepubertal rats' ovarian oocyte development.
    The Anatomical record, 1995, Volume: 243, Issue:4

    Topics: Animals; Female; Melatonin; Oocytes; Pineal Gland; Pregnancy; Prenatal Exposure Delayed Effects; Rat

1995
Prenatal melatonin influences developmental changes of tachykinins in response to estradiol benzoate.
    Peptides, 1999, Volume: 20, Issue:1

    Topics: Animals; Antioxidants; Corpus Striatum; Estradiol; Female; Hypothalamus; Melatonin; Pineal Gland; Pi

1999
Developmental changes of hypothalamic, pituitary and striatal tachykinins in response to testosterone: influence of prenatal melatonin.
    Peptides, 1999, Volume: 20, Issue:4

    Topics: Animals; Corpus Striatum; Female; Hypothalamus; Male; Melatonin; Neurokinin A; Pituitary Gland, Ante

1999
Prenatal melatonin exposure affects luteinizing hormone and hypothalamic and striatal neuropeptide Y in the male rat offspring.
    Neuroscience letters, 2000, Oct-13, Volume: 292, Issue:3

    Topics: Aging; Animals; Corpus Striatum; Female; Gene Expression Regulation, Developmental; Hypothalamus; Lu

2000
Effect of prenatal melatonin exposure on gonadotropins and prolactin secretion in male and female rat pups.
    European journal of pharmacology, 2001, Jul-27, Volume: 424, Issue:3

    Topics: Animals; Animals, Newborn; Female; Follicle Stimulating Hormone; Free Radical Scavengers; Gonadotrop

2001
Effects of maternal-melatonin treatment on open-field behaviors and hypertensive phenotype in spontaneously hypertensive rats' (SHR) offspring.
    Experimental animals, 2002, Volume: 51, Issue:1

    Topics: Animals; Behavior, Animal; Blood Pressure; Body Weight; Exploratory Behavior; Female; Hypertension;

2002
Melatonin administration during pregnancy retards sexual maturation of female offspring in the rat.
    Journal of pineal research, 1991, Volume: 11, Issue:1

    Topics: Animals; Animals, Newborn; Estrus; Female; Luteinizing Hormone; Melatonin; Pineal Gland; Pregnancy;

1991
Maternal melatonin treatment influences rates of neonatal development of meadow vole pups.
    Biology of reproduction, 1989, Volume: 40, Issue:3

    Topics: Animals; Arvicolinae; Birth Weight; Energy Intake; Female; Hair; Lactation; Male; Melatonin; Periodi

1989