melatonin has been researched along with Cystic Fibrosis in 2 studies
Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Melatonin levels were measured serially at intervals from 1800h in the evening until 1200h on the next day." | 6.82 | The pharmacokinetics and toxicity of morning vs. evening tobramycin dosing for pulmonary exacerbations of cystic fibrosis: A randomised comparison. ( Jain, K; Knox, AJ; Koch, BC; Prayle, AP; Smyth, AR; Touw, DJ; Watson, A, 2016) |
| "Melatonin levels were measured serially at intervals from 1800h in the evening until 1200h on the next day." | 2.82 | The pharmacokinetics and toxicity of morning vs. evening tobramycin dosing for pulmonary exacerbations of cystic fibrosis: A randomised comparison. ( Jain, K; Knox, AJ; Koch, BC; Prayle, AP; Smyth, AR; Touw, DJ; Watson, A, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Prayle, AP | 1 |
| Jain, K | 1 |
| Touw, DJ | 1 |
| Koch, BC | 1 |
| Knox, AJ | 1 |
| Watson, A | 1 |
| Smyth, AR | 1 |
| de Castro-Silva, C | 1 |
| de Bruin, VM | 1 |
| Cunha, GM | 1 |
| Nunes, DM | 1 |
| Medeiros, CA | 1 |
| de Bruin, PF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Circadian Rhythm In Tobramycin Elimination In Cystic Fibrosis (CRITIC) A Randomized Pharmacokinetic Comparison of Tobramycin in Cystic Fibrosis[NCT01207245] | Phase 4 | 18 participants (Actual) | Interventional | 2011-05-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for melatonin and Cystic Fibrosis
| Article | Year |
|---|---|
The pharmacokinetics and toxicity of morning vs. evening tobramycin dosing for pulmonary exacerbations of cystic fibrosis: A randomised comparison.
Topics: Adolescent; Aminoglycosides; Anti-Bacterial Agents; Child; Circadian Rhythm; Cystic Fibrosis; Drug A | 2016 |
Melatonin improves sleep and reduces nitrite in the exhaled breath condensate in cystic fibrosis--a randomized, double-blind placebo-controlled study.
Topics: Adolescent; Adult; Breath Tests; Child; Cystic Fibrosis; Double-Blind Method; Female; Humans; Male; | 2010 |