Page last updated: 2024-10-19

melatonin and Cushing Syndrome

melatonin has been researched along with Cushing Syndrome in 10 studies

Cushing Syndrome: A condition caused by prolonged exposure to excess levels of cortisol (HYDROCORTISONE) or other GLUCOCORTICOIDS from endogenous or exogenous sources. It is characterized by upper body OBESITY; OSTEOPOROSIS; HYPERTENSION; DIABETES MELLITUS; HIRSUTISM; AMENORRHEA; and excess body fluid. Endogenous Cushing syndrome or spontaneous hypercortisolism is divided into two groups, those due to an excess of ADRENOCORTICOTROPIN and those that are ACTH-independent.

Research Excerpts

ExcerptRelevanceReference
"In this clinical study using a follow-up approach, we investigated the circadian melatonin secretion and immune parameters of patients with corticotropin-dependent (Cushing's disease) and corticotropin-independent Cushing's syndrome."7.74Melatonin secretion and non-specific immune responses are differentially expressed in corticotropin-dependent and corticotropin-independent Cushing's syndrome. ( Konakchieva, R; Kumanov, P; Manchev, S; Robeva, R; Tomova, A, 2008)
"We evaluated the 24-h profile of serum melatonin (MT) in 16 patients with Cushing's syndrome (11 pituitary- and 5 adrenal-dependent) aged 38."7.69Circadian profile of serum melatonin in patients with Cushing's syndrome or acromegaly. ( Alì, A; Angeli, A; Borretta, G; Codegone, A; Paccotti, P; Pia, A; Piovesan, A; Reimondo, G; Terzolo, M; Torta, M, 1995)
"We evaluated the circadian profiles of serum melatonin (MT) and cortisol in 6 patients with Cushing's disease while those of serum MT and GH were evaluated in 8 patients with acromegaly."7.68Circadian profile of serum melatonin in Cushing's disease and acromegaly. ( Angeli, A; Borretta, G; Buniva, T; Osella, G; Paccotti, P; Piovesan, A; Terzolo, M; Torta, M, 1990)
"To determine the effect of hypercortisolaemia on the melatonin circadian secretion 12 patients with pituitary or adrenal dependent Cushing's syndrome and 5 healthy controls were studied."7.67Decreased melatonin concentration in Cushing's syndrome. ( Kasperlik-Zatuska, A; Soszyński, P; Stowińska-Srzednicka, J; Zgliczyński, S, 1989)
"The concentrations of plasma melatonin and cortisol were determined every 20 min during a 24 h period in 6 women aged 24 to 45 years with Cushing's syndrome of differing aetiologies (4 adrenal adenomas, 2 adrenal hyperplasia)."7.6624 hour melatonin secretory pattern in Cushing's syndrome. ( Bajard, L; Estour, B; Fevre-Montange, M; Tourniaire, J, 1983)
"In this clinical study using a follow-up approach, we investigated the circadian melatonin secretion and immune parameters of patients with corticotropin-dependent (Cushing's disease) and corticotropin-independent Cushing's syndrome."3.74Melatonin secretion and non-specific immune responses are differentially expressed in corticotropin-dependent and corticotropin-independent Cushing's syndrome. ( Konakchieva, R; Kumanov, P; Manchev, S; Robeva, R; Tomova, A, 2008)
"We evaluated the 24-h profile of serum melatonin (MT) in 16 patients with Cushing's syndrome (11 pituitary- and 5 adrenal-dependent) aged 38."3.69Circadian profile of serum melatonin in patients with Cushing's syndrome or acromegaly. ( Alì, A; Angeli, A; Borretta, G; Codegone, A; Paccotti, P; Pia, A; Piovesan, A; Reimondo, G; Terzolo, M; Torta, M, 1995)
"We evaluated the circadian profiles of serum melatonin (MT) and cortisol in 6 patients with Cushing's disease while those of serum MT and GH were evaluated in 8 patients with acromegaly."3.68Circadian profile of serum melatonin in Cushing's disease and acromegaly. ( Angeli, A; Borretta, G; Buniva, T; Osella, G; Paccotti, P; Piovesan, A; Terzolo, M; Torta, M, 1990)
"To determine the effect of hypercortisolaemia on the melatonin circadian secretion 12 patients with pituitary or adrenal dependent Cushing's syndrome and 5 healthy controls were studied."3.67Decreased melatonin concentration in Cushing's syndrome. ( Kasperlik-Zatuska, A; Soszyński, P; Stowińska-Srzednicka, J; Zgliczyński, S, 1989)
"The concentrations of plasma melatonin and cortisol were determined every 20 min during a 24 h period in 6 women aged 24 to 45 years with Cushing's syndrome of differing aetiologies (4 adrenal adenomas, 2 adrenal hyperplasia)."3.6624 hour melatonin secretory pattern in Cushing's syndrome. ( Bajard, L; Estour, B; Fevre-Montange, M; Tourniaire, J, 1983)
"Melatonin is a hormone mainly secreted by the pineal gland during the dark phase of the light-dark cycle."2.41[Melatonin. I. Physiology of its secretion]. ( Bruls, E; Crasson, M; Legros, JJ, 2000)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19906 (60.00)18.7374
1990's2 (20.00)18.2507
2000's2 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tomova, A1
Kumanov, P1
Robeva, R1
Manchev, S1
Konakchieva, R1
Wetterberg, L2
Beck-Friis, J1
Kjellman, BF1
Ljunggren, JG1
Dempsey, RJ1
Chandler, WF1
Fevre-Montange, M2
Tourniaire, J2
Estour, B1
Bajard, L1
Terzolo, M2
Piovesan, A2
Alì, A1
Codegone, A1
Pia, A1
Reimondo, G1
Torta, M2
Paccotti, P2
Borretta, G2
Angeli, A2
Bruls, E1
Crasson, M1
Legros, JJ1
Buniva, T1
Osella, G1
Soszyński, P1
Stowińska-Srzednicka, J1
Kasperlik-Zatuska, A1
Zgliczyński, S1
Abou Samra, A1
Dechaud, H1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Observational Prospective Multicentric Study on Melatonin and Cortisol Circadian Rhythm in CusHing SyndrOme Patients in Active Phase and dUring RemiSsion.[NCT03343470]15 participants (Anticipated)Observational2017-11-08Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for melatonin and Cushing Syndrome

ArticleYear
The relationship between the pineal gland and the pituitary--adrenal axis in health, endocrine and psychiatric conditions.
    Psychoneuroendocrinology, 1983, Volume: 8, Issue:1

    Topics: Adenoma; Adrenal Cortex Function Tests; Adrenocorticotropic Hormone; Circadian Rhythm; Cushing Syndr

1983
[Melatonin. I. Physiology of its secretion].
    Revue medicale de Liege, 2000, Volume: 55, Issue:8

    Topics: Alcoholism; Body Constitution; Circadian Rhythm; Cushing Syndrome; Electromagnetic Fields; Female; H

2000

Other Studies

8 other studies available for melatonin and Cushing Syndrome

ArticleYear
Melatonin secretion and non-specific immune responses are differentially expressed in corticotropin-dependent and corticotropin-independent Cushing's syndrome.
    Medical science monitor : international medical journal of experimental and clinical research, 2008, Volume: 14, Issue:6

    Topics: Adrenocorticotropic Hormone; Adult; Case-Control Studies; Cushing Syndrome; Female; Humans; Immunogl

2008
Circadian rhythms in melatonin and cortisol secretion in depression.
    Advances in biochemical psychopharmacology, 1984, Volume: 39

    Topics: Bipolar Disorder; Circadian Rhythm; Cushing Syndrome; Depressive Disorder; Dexamethasone; Humans; Hy

1984
Abnormal serum melatonin levels in patients with intrasellar tumors.
    Neurosurgery, 1984, Volume: 15, Issue:6

    Topics: Adenoma; Adult; Aged; Brain Neoplasms; Craniopharyngioma; Cushing Syndrome; Female; Humans; Male; Me

1984
24 hour melatonin secretory pattern in Cushing's syndrome.
    Clinical endocrinology, 1983, Volume: 19, Issue:2

    Topics: Adrenal Glands; Adult; Circadian Rhythm; Cushing Syndrome; Female; Humans; Hydrocortisone; Male; Mel

1983
Circadian profile of serum melatonin in patients with Cushing's syndrome or acromegaly.
    Journal of endocrinological investigation, 1995, Volume: 18, Issue:1

    Topics: Acromegaly; Adrenocorticotropic Hormone; Adult; Circadian Rhythm; Cushing Syndrome; Female; Growth H

1995
Circadian profile of serum melatonin in Cushing's disease and acromegaly.
    Chronobiology international, 1990, Volume: 7, Issue:3

    Topics: Acromegaly; Adolescent; Adult; Circadian Rhythm; Cushing Syndrome; Growth Hormone; Humans; Hydrocort

1990
Decreased melatonin concentration in Cushing's syndrome.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1989, Volume: 21, Issue:12

    Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Cir

1989
[Melatonin and the corticotropic function].
    Bulletin de l'Academie nationale de medecine, 1986, Volume: 170, Issue:6

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Animals; Circadian Rhythm; Cor

1986