melatonin has been researched along with Convulsive Generalized Seizure Disorder in 6 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of the study was to assess diurnal melatonin secretion in children with refractory epilepsy (N=74) as compared to children without epileptic seizures (N=37) and to compare melatonin secretion in children with focal and generalized refractory epilepsy." | 7.76 | Melatonin and childhood refractory epilepsy--a pilot study. ( Dec, R; Jamroz, E; Marszał, E; Paprocka, J, 2010) |
| "Add-on melatonin with valproate for generalized epilepsy with generalized onset motor seizures in adults can achieve a significantly better clinical outcome by reducing the seizure frequency, severity and attaining a better seizure-free rate in comparison to the control group." | 7.01 | Effect of add-on melatonin on seizure outcome, neuronal damage, oxidative stress, and quality of life in generalized epilepsy with generalized onset motor seizures in adults: A randomized controlled trial. ( Jena, M; Jha, M; Maiti, R; Mishra, A; Mishra, BR; Verma, N, 2021) |
| "The aim of the study was to assess diurnal melatonin secretion in children with refractory epilepsy (N=74) as compared to children without epileptic seizures (N=37) and to compare melatonin secretion in children with focal and generalized refractory epilepsy." | 3.76 | Melatonin and childhood refractory epilepsy--a pilot study. ( Dec, R; Jamroz, E; Marszał, E; Paprocka, J, 2010) |
| "Add-on melatonin with valproate for generalized epilepsy with generalized onset motor seizures in adults can achieve a significantly better clinical outcome by reducing the seizure frequency, severity and attaining a better seizure-free rate in comparison to the control group." | 3.01 | Effect of add-on melatonin on seizure outcome, neuronal damage, oxidative stress, and quality of life in generalized epilepsy with generalized onset motor seizures in adults: A randomized controlled trial. ( Jena, M; Jha, M; Maiti, R; Mishra, A; Mishra, BR; Verma, N, 2021) |
| "Five patients with generalized epilepsy underwent a protocol whereby their sleep/wake schedule was evenly distributed across the circadian cycle while undergoing full-montage electroencephalography and hourly plasma melatonin measurements." | 1.35 | Is there a circadian variation of epileptiform abnormalities in idiopathic generalized epilepsy? ( Bromfield, EB; Pavlova, MK; Scheer, FA; Shea, SA, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Atacan Yaşgüçlükal, M | 1 |
| Ayça, S | 1 |
| Demirbilek, V | 1 |
| Saltık, S | 1 |
| Yalçınkaya, C | 1 |
| Erdoğan Döventaş, Y | 1 |
| Çokar, Ö | 1 |
| Verma, N | 1 |
| Maiti, R | 1 |
| Mishra, BR | 1 |
| Jha, M | 1 |
| Jena, M | 1 |
| Mishra, A | 1 |
| Manni, R | 1 |
| De Icco, R | 1 |
| Cremascoli, R | 1 |
| Ferrera, G | 1 |
| Furia, F | 1 |
| Zambrelli, E | 1 |
| Canevini, MP | 1 |
| Terzaghi, M | 1 |
| Pavlova, MK | 1 |
| Shea, SA | 1 |
| Scheer, FA | 1 |
| Bromfield, EB | 1 |
| Paprocka, J | 1 |
| Dec, R | 1 |
| Jamroz, E | 1 |
| Marszał, E | 1 |
| Gupta, M | 1 |
| Aneja, S | 1 |
| Kohli, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Melatonin on Seizure Outcome, Neuronal Damage and Quality of Life in Patients With Generalized Epilepsy: A Randomized, add-on Placebo-controlled Clinical Trial[NCT03590197] | Phase 4 | 104 participants (Actual) | Interventional | 2018-08-06 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for melatonin and Convulsive Generalized Seizure Disorder
| Article | Year |
|---|---|
Effect of add-on melatonin on seizure outcome, neuronal damage, oxidative stress, and quality of life in generalized epilepsy with generalized onset motor seizures in adults: A randomized controlled trial.
Topics: Adolescent; Adult; Anticonvulsants; Double-Blind Method; Drug Therapy, Combination; Epilepsy, Genera | 2021 |
Add-on melatonin improves sleep behavior in children with epilepsy: randomized, double-blind, placebo-controlled trial.
Topics: Anticonvulsants; Child; Child, Preschool; Double-Blind Method; Drug Therapy, Combination; Epilepsies | 2005 |
4 other studies available for melatonin and Convulsive Generalized Seizure Disorder
| Article | Year |
|---|---|
Serum Levels of Neuropeptides in Epileptic Encephalopathy With Spike-and-Wave Activation in Sleep.
Topics: Adolescent; Child; Child, Preschool; Electroencephalography; Epilepsies, Partial; Epilepsy, Generali | 2023 |
Circadian phase typing in idiopathic generalized epilepsy: Dim light melatonin onset and patterns of melatonin secretion-Semicurve findings in adult patients.
Topics: Adolescent; Adult; Circadian Rhythm; Epilepsy, Generalized; Female; Humans; Male; Melatonin; Middle | 2016 |
Is there a circadian variation of epileptiform abnormalities in idiopathic generalized epilepsy?
Topics: Adolescent; Adult; Chronobiology Disorders; Circadian Rhythm; Electroencephalography; Epilepsy, Gene | 2009 |
Melatonin and childhood refractory epilepsy--a pilot study.
Topics: Adolescent; Case-Control Studies; Child; Child, Preschool; Circadian Rhythm; Epilepsy; Epilepsy, Gen | 2010 |