melatonin has been researched along with Complications, Pregnancy in 23 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Adopting an integrative approach, by combining studies of cardiovascular function with those at cellular and molecular levels, this study investigated whether maternal treatment with melatonin protects against programmed cardiovascular dysfunction in the offspring using an established rodent model of hypoxic pregnancy." | 8.12 | Maternal melatonin: Effective intervention against developmental programming of cardiovascular dysfunction in adult offspring of complicated pregnancy. ( Blanco, CE; Camm, EJ; Galli, GLJ; Giussani, DA; Hansell, JA; Herrera, EA; Lock, MC; Patey, OV; Richter, HG; Trafford, AW; Villamor, E, 2022) |
| "Melatonin and interleukin -10 were significantly lower in subjects with intrahepatic cholestasis of pregnancy (p=0." | 8.02 | The Role of Melatonin, IL-8 and IL-10 in Intrahepatic Cholestasis of Pregnancy. ( Çalışkan, C; Çelik, S; Guve, H, 2021) |
| "Female Swiss Albino rats were divided into five groups: intact control group; saline control group; epilepsy group; epilepsy plus Px group; and melatonin-treated epilepsy plus Px group." | 7.74 | Efficacy of melatonin on offspring liver maturation in pinealectomized pregnant rats subjected to experimental epilepsy. ( Ateş, U; Baka, M; Turgut, M; Uyanikgil, Y; Yavaşoğlu, A; Yurtseven, M, 2007) |
| " The aim of this study was to investigate the protective effects in rat maternal and fetal livers as also the placenta of melatonin or silymarin against the oxidative stress and apoptosis induced by maternal obstructive cholestasis during the last third of pregnancy (OCP)." | 7.74 | Multiple protective effects of melatonin against maternal cholestasis-induced oxidative stress and apoptosis in the rat fetal liver-placenta-maternal liver trio. ( Castaño, B; Gonzalez-Buitrago, JM; Marin, JJ; Perez, MJ, 2007) |
| "Treatment with melatonin might result in a wide range of health benefits, including improved quality of life and reduced healthcare costs." | 6.48 | Potential utility of melatonin as an antioxidant during pregnancy and in the perinatal period. ( Aversa, S; Barberi, I; Gitto, E; Pellegrino, S; Reiter, RJ, 2012) |
| "Melatonin also acts as a potent endogenous antioxidant by scavenging free radicals and upregulating antioxidant pathways." | 5.35 | Melatonin improves placental efficiency and birth weight and increases the placental expression of antioxidant enzymes in undernourished pregnancy. ( Giussani, DA; Hansell, JA; Raut, S; Richter, HG, 2009) |
| "The widely accepted standard therapy for cutaneous sarcoidosis includes corticosteroids, antimalarials, and methotrexate." | 4.84 | Cutaneous sarcoidosis therapy updated. ( Badgwell, C; Rosen, T, 2007) |
| "Adopting an integrative approach, by combining studies of cardiovascular function with those at cellular and molecular levels, this study investigated whether maternal treatment with melatonin protects against programmed cardiovascular dysfunction in the offspring using an established rodent model of hypoxic pregnancy." | 4.12 | Maternal melatonin: Effective intervention against developmental programming of cardiovascular dysfunction in adult offspring of complicated pregnancy. ( Blanco, CE; Camm, EJ; Galli, GLJ; Giussani, DA; Hansell, JA; Herrera, EA; Lock, MC; Patey, OV; Richter, HG; Trafford, AW; Villamor, E, 2022) |
| "Melatonin and interleukin -10 were significantly lower in subjects with intrahepatic cholestasis of pregnancy (p=0." | 4.02 | The Role of Melatonin, IL-8 and IL-10 in Intrahepatic Cholestasis of Pregnancy. ( Çalışkan, C; Çelik, S; Guve, H, 2021) |
| "We investigated the effects of melatonin on rats with induced hypothyroidism during gestation as well as its effect on the development of the gonads of their offspring." | 3.96 | Effect of melatonin on gonad and thyroid development of offspring of hypothyroid pregnant rats. ( Alves, RDC; Baptista, MGP; D Assunção, CG; de Albuquerque, YML; Ferreira, CGM; Teixeira, ÁAC; Wanderley Teixeira, V, 2020) |
| "Several novel animal studies have shown that intrauterine metabolic programming can be modified in the event of reduced melatonin synthesis during pregnancy, leading to glucose intolerance and insulin resistance in the offspring." | 3.91 | Reduced melatonin synthesis in pregnant night workers: Metabolic implications for offspring. ( Amaral, F; Cipolla-Neto, J; Lowden, A; Moreno, CRC; Nehme, PA; Skene, DJ, 2019) |
| "Female Swiss Albino rats were divided into five groups: intact control group; saline control group; epilepsy group; epilepsy plus Px group; and melatonin-treated epilepsy plus Px group." | 3.74 | Efficacy of melatonin on offspring liver maturation in pinealectomized pregnant rats subjected to experimental epilepsy. ( Ateş, U; Baka, M; Turgut, M; Uyanikgil, Y; Yavaşoğlu, A; Yurtseven, M, 2007) |
| " The aim of this study was to investigate the protective effects in rat maternal and fetal livers as also the placenta of melatonin or silymarin against the oxidative stress and apoptosis induced by maternal obstructive cholestasis during the last third of pregnancy (OCP)." | 3.74 | Multiple protective effects of melatonin against maternal cholestasis-induced oxidative stress and apoptosis in the rat fetal liver-placenta-maternal liver trio. ( Castaño, B; Gonzalez-Buitrago, JM; Marin, JJ; Perez, MJ, 2007) |
| "Ten pregnant women with DSM-IV major depressive disorder were randomly assigned from April 2000 to January 2002 to a 5-week clinical trial with either a 7000 lux (active) or 500 lux (placebo) light box." | 2.71 | Randomized clinical trial of bright light therapy for antepartum depression: preliminary findings. ( Epperson, CN; Hanusa, BH; Oren, DA; Peindl, KS; Terman, JS; Terman, M; Wisner, KL, 2004) |
| "Melatonin treatment, alterations of the normal light:dark cycle and light exposure at night." | 2.50 | Melatonin and the circadian system: contributions to successful female reproduction. ( Reiter, RJ; Tamura, H; Tan, DX; Xu, XY, 2014) |
| "Treatment with melatonin might result in a wide range of health benefits, including improved quality of life and reduced healthcare costs." | 2.48 | Potential utility of melatonin as an antioxidant during pregnancy and in the perinatal period. ( Aversa, S; Barberi, I; Gitto, E; Pellegrino, S; Reiter, RJ, 2012) |
| "Oxidative stress is present in pregnancy complications." | 1.43 | Maternal plasma antioxidant status in the first trimester of pregnancy and development of obstetric complications. ( Aguilera, Y; Arribas, SM; Condezo-Hoyos, L; De La Calle, M; Gómez-Rioja, R; González, MC; Gutiérrez-Arzapalo, PY; Herrera, T; López De Pablo, ÁL; López-Giménez, MR; Martín-Cabrejas, MA; Montero, P; Mora-Urda, AI; Moreno-Jiménez, B; Ramiro-Cortijo, D; Rodríguez-Rodríguez, P, 2016) |
| "Melatonin also acts as a potent endogenous antioxidant by scavenging free radicals and upregulating antioxidant pathways." | 1.35 | Melatonin improves placental efficiency and birth weight and increases the placental expression of antioxidant enzymes in undernourished pregnancy. ( Giussani, DA; Hansell, JA; Raut, S; Richter, HG, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (8.70) | 18.2507 |
| 2000's | 6 (26.09) | 29.6817 |
| 2010's | 11 (47.83) | 24.3611 |
| 2020's | 4 (17.39) | 2.80 |
| Authors | Studies |
|---|---|
| Hansell, JA | 2 |
| Richter, HG | 2 |
| Camm, EJ | 1 |
| Herrera, EA | 1 |
| Blanco, CE | 1 |
| Villamor, E | 1 |
| Patey, OV | 1 |
| Lock, MC | 1 |
| Trafford, AW | 1 |
| Galli, GLJ | 1 |
| Giussani, DA | 2 |
| Nehme, PA | 1 |
| Amaral, F | 1 |
| Lowden, A | 1 |
| Skene, DJ | 1 |
| Cipolla-Neto, J | 1 |
| Moreno, CRC | 1 |
| Kaur, S | 1 |
| Teoh, AN | 1 |
| Shukri, NHM | 1 |
| Shafie, SR | 1 |
| Bustami, NA | 1 |
| Takahashi, M | 1 |
| Lim, PJ | 1 |
| Shibata, S | 1 |
| de Albuquerque, YML | 1 |
| Ferreira, CGM | 1 |
| D Assunção, CG | 1 |
| Baptista, MGP | 1 |
| Alves, RDC | 1 |
| Wanderley Teixeira, V | 1 |
| Teixeira, ÁAC | 1 |
| Çelik, S | 2 |
| Guve, H | 1 |
| Çalışkan, C | 1 |
| Man, GCW | 1 |
| Zhang, T | 1 |
| Chen, X | 1 |
| Wang, J | 1 |
| Wu, F | 1 |
| Liu, Y | 1 |
| Wang, CC | 1 |
| Cheong, Y | 1 |
| Li, TC | 1 |
| Han, L | 1 |
| Wang, H | 1 |
| Li, L | 1 |
| Li, X | 1 |
| Ge, J | 1 |
| Reiter, RJ | 3 |
| Wang, Q | 1 |
| Parry, BL | 3 |
| Meliska, CJ | 3 |
| Lopez, AM | 3 |
| Sorenson, DL | 3 |
| Martinez, LF | 3 |
| Orff, HJ | 1 |
| Hauger, RL | 1 |
| Kripke, DF | 2 |
| Sharkey, KM | 1 |
| Pearlstein, TB | 1 |
| Carskadon, MA | 1 |
| Nowakowski, S | 2 |
| Elliott, J | 1 |
| Tamura, H | 1 |
| Tan, DX | 1 |
| Xu, XY | 1 |
| Ramiro-Cortijo, D | 1 |
| Herrera, T | 1 |
| Rodríguez-Rodríguez, P | 1 |
| López De Pablo, ÁL | 1 |
| De La Calle, M | 1 |
| López-Giménez, MR | 1 |
| Mora-Urda, AI | 1 |
| Gutiérrez-Arzapalo, PY | 1 |
| Gómez-Rioja, R | 1 |
| Aguilera, Y | 1 |
| Martín-Cabrejas, MA | 1 |
| Condezo-Hoyos, L | 1 |
| González, MC | 1 |
| Montero, P | 1 |
| Moreno-Jiménez, B | 1 |
| Arribas, SM | 1 |
| Raut, S | 1 |
| Aversa, S | 1 |
| Pellegrino, S | 1 |
| Barberi, I | 1 |
| Gitto, E | 1 |
| Bagci, S | 1 |
| Berner, AL | 1 |
| Reinsberg, J | 1 |
| Gast, AS | 1 |
| Zur, B | 1 |
| Welzing, L | 1 |
| Bartmann, P | 1 |
| Mueller, A | 1 |
| Posadas, ES | 1 |
| Hauger, R | 1 |
| Epperson, CN | 1 |
| Terman, M | 1 |
| Terman, JS | 1 |
| Hanusa, BH | 1 |
| Oren, DA | 1 |
| Peindl, KS | 1 |
| Wisner, KL | 1 |
| Uyanikgil, Y | 2 |
| Turgut, M | 2 |
| Ateş, U | 2 |
| Baka, M | 2 |
| Yurtseven, ME | 1 |
| Badgwell, C | 1 |
| Rosen, T | 1 |
| Yavaşoğlu, A | 1 |
| Yurtseven, M | 1 |
| Perez, MJ | 1 |
| Castaño, B | 1 |
| Gonzalez-Buitrago, JM | 1 |
| Marin, JJ | 1 |
| Suzuki, S | 1 |
| Dennerstein, L | 1 |
| Greenwood, KM | 1 |
| Armstrong, SM | 1 |
| Sano, T | 1 |
| Satohisa, E | 1 |
| Katz, VL | 1 |
| Warren, M | 1 |
| Ekstrom, RD | 1 |
| Mason, G | 1 |
| Heine, A | 1 |
| Golden, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomised, Double-blind, Placebo-controlled Study of Light Therapy for Antepartum Depression[NCT01043289] | 46 participants (Actual) | Interventional | 2004-10-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for melatonin and Complications, Pregnancy
| Article | Year |
|---|---|
The regulations and role of circadian clock and melatonin in uterine receptivity and pregnancy-An immunological perspective.
Topics: Animals; Circadian Clocks; Female; Humans; Melatonin; Pregnancy; Pregnancy Complications; Uterus | 2017 |
Melatonin and the circadian system: contributions to successful female reproduction.
Topics: Animals; Chronobiology Disorders; Circadian Clocks; Circadian Rhythm; Female; Fetus; Humans; Light; | 2014 |
Potential utility of melatonin as an antioxidant during pregnancy and in the perinatal period.
Topics: Adult; Antioxidants; Female; Humans; Infant, Newborn; Melatonin; Oxidative Stress; Perinatal Care; P | 2012 |
Cutaneous sarcoidosis therapy updated.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Allopurinol; Animals; Anti-Inflammatory Agents | 2007 |
2 trials available for melatonin and Complications, Pregnancy
| Article | Year |
|---|---|
Early versus late wake therapy improves mood more in antepartum versus postpartum depression by differentially altering melatonin-sleep timing disturbances.
Topics: Adult; Affect; Circadian Rhythm; Depression, Postpartum; Depressive Disorder, Major; Female; Humans; | 2019 |
Randomized clinical trial of bright light therapy for antepartum depression: preliminary findings.
Topics: Adult; Circadian Rhythm; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Dis | 2004 |
17 other studies available for melatonin and Complications, Pregnancy
| Article | Year |
|---|---|
Maternal melatonin: Effective intervention against developmental programming of cardiovascular dysfunction in adult offspring of complicated pregnancy.
Topics: Animals; Female; Fetal Growth Retardation; Hypoxia; Melatonin; Pregnancy; Pregnancy Complications; R | 2022 |
Reduced melatonin synthesis in pregnant night workers: Metabolic implications for offspring.
Topics: Circadian Rhythm; Energy Metabolism; Female; Fetus; Glucose Intolerance; Humans; Insulin Resistance; | 2019 |
Circadian rhythm and its association with birth and infant outcomes: research protocol of a prospective cohort study.
Topics: Actigraphy; Adult; Circadian Rhythm; Diet Surveys; Eating; Female; Gestational Weight Gain; Humans; | 2020 |
Effect of melatonin on gonad and thyroid development of offspring of hypothyroid pregnant rats.
Topics: Animals; Antioxidants; Antithyroid Agents; Female; Gonads; Hypothyroidism; Melatonin; Pregnancy; Pre | 2020 |
The Role of Melatonin, IL-8 and IL-10 in Intrahepatic Cholestasis of Pregnancy.
Topics: Cholestasis, Intrahepatic; Female; Humans; Interleukin-10; Interleukin-8; Melatonin; Pregnancy; Preg | 2021 |
Melatonin protects against maternal obesity-associated oxidative stress and meiotic defects in oocytes via the SIRT3-SOD2-dependent pathway.
Topics: Acetylation; Animals; Antioxidants; Diet, High-Fat; Drug Evaluation, Preclinical; Embryonic Developm | 2017 |
Circadian phase shifts and mood across the perinatal period in women with a history of major depressive disorder: a preliminary communication.
Topics: Actigraphy; Adult; Affect; Circadian Rhythm; Depressive Disorder, Major; Female; Humans; Light; Mela | 2013 |
Antepartum depression severity is increased during seasonally longer nights: relationship to melatonin and cortisol timing and quantity.
Topics: Adult; Affect; Area Under Curve; Circadian Rhythm; Cross-Sectional Studies; Darkness; Depression; Fe | 2013 |
Maternal plasma antioxidant status in the first trimester of pregnancy and development of obstetric complications.
Topics: Adult; Biomarkers; Catalase; Diet; Female; Glutathione; Glutathione Peroxidase; Humans; Malondialdeh | 2016 |
Melatonin improves placental efficiency and birth weight and increases the placental expression of antioxidant enzymes in undernourished pregnancy.
Topics: Analysis of Variance; Animals; Birth Weight; Catalase; Female; Fetus; Glutathione Peroxidase; Glutat | 2009 |
Melatonin concentration in umbilical cord blood depends on mode of delivery.
Topics: Adult; Cesarean Section; Circadian Rhythm; Delivery, Obstetric; Female; Fetal Blood; Humans; Infant, | 2012 |
The relationship of nocturnal melatonin to estradiol and progesterone in depressed and healthy pregnant women.
Topics: Adult; Analysis of Variance; Body Mass Index; California; Circadian Rhythm; Depressive Disorder; Est | 2012 |
Beneficial effects of melatonin on morphological changes in postnatal cerebellar tissue owing to epileptiform activity during pregnancy in rats: light and immunohistochemical study.
Topics: Animals; Cerebellum; Epilepsy; Female; Immunohistochemistry; Intermediate Filament Proteins; Melaton | 2005 |
Efficacy of melatonin on offspring liver maturation in pinealectomized pregnant rats subjected to experimental epilepsy.
Topics: Animals; Epilepsy; Female; In Situ Nick-End Labeling; Liver; Melatonin; Pineal Gland; Pregnancy; Pre | 2007 |
Multiple protective effects of melatonin against maternal cholestasis-induced oxidative stress and apoptosis in the rat fetal liver-placenta-maternal liver trio.
Topics: Animals; Apoptosis; Body Weight; Cholestasis; Female; Glutathione; Lipid Peroxidation; Liver; Melato | 2007 |
Melatonin and hormonal changes in disturbed sleep during late pregnancy.
Topics: Adult; Circadian Rhythm; Female; Humans; Hydrocortisone; Melatonin; Pregnancy; Pregnancy Complicatio | 1993 |
Psychobiological markers of stress in pregnancy: 6-sulfatoxymelatonin--a longitudinal study.
Topics: Adult; Anxiety; Biomarkers; Female; Gestational Age; Humans; Hydrocortisone; Melatonin; Pregnancy; P | 1999 |