Page last updated: 2024-10-19

melatonin and Colitis, Mucous

melatonin has been researched along with Colitis, Mucous in 31 studies

Research Excerpts

ExcerptRelevanceReference
"Melatonin can be used as part of the treatment of IBS, particularly in patients with constipation-predominant IBS."9.17Influence of melatonin on symptoms of irritable bowel syndrome in postmenopausal women. ( Chojnacki, C; Chojnacki, J; Klupińska, G; Lokieć, K; Pawłowicz, M; Walecka-Kapica, E; Winczyk, K, 2013)
"Compared with placebo, melatonin taken for two weeks significantly decreased mean abdominal pain score (2."9.11Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study. ( Gwee, KA; Ho, KY; Leng, PH; Moochhala, SM; Song, GH, 2005)
"To determine the potential therapeutic effects of melatonin in irritable bowel syndrome (IBS)."9.11Melatonin improves bowel symptoms in female patients with irritable bowel syndrome: a double-blind placebo-controlled study. ( Gwee, KA; Ho, KY; Lu, WZ; Moochhalla, S, 2005)
"Melatonin (MT) exerts a beneficial action in the treatment of many diseases, among them also in irritable bowel syndrome (IBS)."7.76Evaluation of urinary 6-hydroxymelatonin sulphate excretion in women at different age with irritable bowel syndrome. ( Brzozowski, T; Chojnacki, C; Chojnacki, J; Konturek, S; Smigielski, J; Wisniewska-Jarosinska, M, 2010)
"To evaluate melatonin (MEL) secretion and its metabolism to 6-hydroxymelatonin sulfate (6HMS) in patients with irritable bowel syndrome (IBS)."7.75[Melatonin secretion and metabolism in patients with irritable bowel syndrome]. ( Chojnacki, J; Harasiuk, A; Moskwa-Fortuna, A; Stepień, A; Wisniewska-Jarosińska, M, 2009)
"In patients with sleep disorders, significant improvement in sleep parameters, including subjective sleep quality, sleep latency, sleep duration, sleep efficiency, and daytime dysfunction, was observed, while in patients without sleep disorders, there was no significant improvement in sleep parameters."7.30The effect of melatonin on irritable bowel syndrome patients with and without sleep disorders: a randomized double-blinded placebo-controlled trial study. ( Abbasian, S; Faghih Dinevari, M; Jabbaripour Sarmadian, A; Jafarzadeh, F; Nikniaz, Z; Riazi, A, 2023)
"Melatonin was found to play an important role in gastrointestinal smooth muscle motility."7.01The efficacy of exogenous melatonin supplement in ameliorating irritable bowel syndrome severity: A meta-analysis of randomized controlled trials. ( Chen, KH; Chen, TY; Chen, YW; Cheng, YS; Chu, CS; Hsu, CW; Hsu, CY; Liang, CS; Lin, PY; Su, KP; Sun, CK; Tseng, PT; Wu, MK; Wu, YC; Yeh, PY; Zeng, BS; Zeng, BY, 2023)
"Melatonin is a powerful antioxidant that resists oxidative stress due to its capacity to directly scavenge reactive species, to modulate the antioxidant defense system by increasing the activities of antioxidant enzymes, and to stimulate the innate immune response through its direct and indirect actions."6.55Melatonin's role as a co-adjuvant treatment in colonic diseases: A review. ( Alatorre-Jiménez, MA; Antoñanzas-Lombarte, Á; Buisac-Ramón, C; Castán-Ruiz, S; Esteban-Zubero, E; García, JJ; López-Pingarrón, L; Ochoa-Moneo, P; Reiter, RJ; Rivas-Jiménez, M; Tan, DX, 2017)
"Melatonin treatment has an extremely wide margin of safety though it may cause minor adverse effects, such as headache, rash and nightmares."6.50Melatonin for the treatment of irritable bowel syndrome. ( Ho, KY; Siah, KT; Wong, RK, 2014)
"Melatonin plays a beneficial role in gut motility and immunity."5.56Increased Expression of Colonic Mucosal Melatonin in Patients with Irritable Bowel Syndrome Correlated with Gut Dysbiosis. ( Duan, L; He, M; Liu, Z; Pei, F; Sun, Q; Wang, B; Wei, H; Zhang, J; Zhang, L; Zhu, S, 2020)
"Melatonin can be used as part of the treatment of IBS, particularly in patients with constipation-predominant IBS."5.17Influence of melatonin on symptoms of irritable bowel syndrome in postmenopausal women. ( Chojnacki, C; Chojnacki, J; Klupińska, G; Lokieć, K; Pawłowicz, M; Walecka-Kapica, E; Winczyk, K, 2013)
"Compared with placebo, melatonin taken for two weeks significantly decreased mean abdominal pain score (2."5.11Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study. ( Gwee, KA; Ho, KY; Leng, PH; Moochhala, SM; Song, GH, 2005)
"To determine the potential therapeutic effects of melatonin in irritable bowel syndrome (IBS)."5.11Melatonin improves bowel symptoms in female patients with irritable bowel syndrome: a double-blind placebo-controlled study. ( Gwee, KA; Ho, KY; Lu, WZ; Moochhalla, S, 2005)
"Melatonin (MT) exerts a beneficial action in the treatment of many diseases, among them also in irritable bowel syndrome (IBS)."3.76Evaluation of urinary 6-hydroxymelatonin sulphate excretion in women at different age with irritable bowel syndrome. ( Brzozowski, T; Chojnacki, C; Chojnacki, J; Konturek, S; Smigielski, J; Wisniewska-Jarosinska, M, 2010)
"To evaluate melatonin (MEL) secretion and its metabolism to 6-hydroxymelatonin sulfate (6HMS) in patients with irritable bowel syndrome (IBS)."3.75[Melatonin secretion and metabolism in patients with irritable bowel syndrome]. ( Chojnacki, J; Harasiuk, A; Moskwa-Fortuna, A; Stepień, A; Wisniewska-Jarosińska, M, 2009)
"The purpose of the study was to evaluate the clinical effectiveness of melatonin (melaxen, Unipharm, USA), and its influence on the ultrastructural and histological features on the colon mucosa (CM) in patients with irritable bowel syndrome (IBS) corresponding to Rome criteria II."3.73[Irritated bowel syndrome: clinicomorphological aspects of treatment with melaxen]. ( Komarov, FI; Malinovskaia, NK; Raĭkhlin, NT; Rapoport, SI; Rumiantseva, AI; Voznesenskaia, LA, 2006)
"In patients with sleep disorders, significant improvement in sleep parameters, including subjective sleep quality, sleep latency, sleep duration, sleep efficiency, and daytime dysfunction, was observed, while in patients without sleep disorders, there was no significant improvement in sleep parameters."3.30The effect of melatonin on irritable bowel syndrome patients with and without sleep disorders: a randomized double-blinded placebo-controlled trial study. ( Abbasian, S; Faghih Dinevari, M; Jabbaripour Sarmadian, A; Jafarzadeh, F; Nikniaz, Z; Riazi, A, 2023)
"Melatonin was found to play an important role in gastrointestinal smooth muscle motility."3.01The efficacy of exogenous melatonin supplement in ameliorating irritable bowel syndrome severity: A meta-analysis of randomized controlled trials. ( Chen, KH; Chen, TY; Chen, YW; Cheng, YS; Chu, CS; Hsu, CW; Hsu, CY; Liang, CS; Lin, PY; Su, KP; Sun, CK; Tseng, PT; Wu, MK; Wu, YC; Yeh, PY; Zeng, BS; Zeng, BY, 2023)
"The melatonin treatment of the control subjects caused an increase in CTT (mean+/-SD) from 27."2.74The effects of melatonin on colonic transit time in normal controls and IBS patients. ( Gwee, KA; Ho, KY; Lu, WZ; Song, GH, 2009)
"Melatonin is a powerful antioxidant that resists oxidative stress due to its capacity to directly scavenge reactive species, to modulate the antioxidant defense system by increasing the activities of antioxidant enzymes, and to stimulate the innate immune response through its direct and indirect actions."2.55Melatonin's role as a co-adjuvant treatment in colonic diseases: A review. ( Alatorre-Jiménez, MA; Antoñanzas-Lombarte, Á; Buisac-Ramón, C; Castán-Ruiz, S; Esteban-Zubero, E; García, JJ; López-Pingarrón, L; Ochoa-Moneo, P; Reiter, RJ; Rivas-Jiménez, M; Tan, DX, 2017)
"Melatonin treatment has an extremely wide margin of safety though it may cause minor adverse effects, such as headache, rash and nightmares."2.50Melatonin for the treatment of irritable bowel syndrome. ( Ho, KY; Siah, KT; Wong, RK, 2014)
"Melatonin is an endogenous indoleamine, produced mainly by the pineal gland."2.47Analgesic effects of melatonin: a review of current evidence from experimental and clinical studies. ( Amirian, I; Gögenur, I; Reiter, RJ; Rosenberg, J; Wilhelmsen, M, 2011)
"The fecal microbiota during IBS symptom exacerbation exhibited significant differences in the phylogenic pattern and short-chain fatty acid compared with fecal samples during defecation when symptoms were not exacerbated."1.72Omics profiles of fecal and oral microbiota change in irritable bowel syndrome patients with diarrhea and symptom exacerbation. ( Fukuda, S; Fukudo, S; Gotoh, Y; Hayashi, T; Kasahara, Y; Kawashima, J; Kurokawa, K; Mori, H; Nakamura, K; Sato, Y; Tanaka, Y; Yamashita, R, 2022)
"Melatonin plays a beneficial role in gut motility and immunity."1.56Increased Expression of Colonic Mucosal Melatonin in Patients with Irritable Bowel Syndrome Correlated with Gut Dysbiosis. ( Duan, L; He, M; Liu, Z; Pei, F; Sun, Q; Wang, B; Wei, H; Zhang, J; Zhang, L; Zhu, S, 2020)
"Melatonin could inhibit WAS-induced fecal output pellets by inactivating the 5-HT pathway, may interact with calcium channel and inhibit the influx of calcium."1.39The inhibitory effect of melatonin on colonic motility disorders induced by water avoidance stress in rats. ( Liang, CB; Luo, HS; Tan, W; Xia, H; Zhou, W, 2013)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's12 (38.71)29.6817
2010's13 (41.94)24.3611
2020's6 (19.35)2.80

Authors

AuthorsStudies
Tanaka, Y1
Yamashita, R1
Kawashima, J1
Mori, H1
Kurokawa, K1
Fukuda, S1
Gotoh, Y1
Nakamura, K1
Hayashi, T1
Kasahara, Y1
Sato, Y1
Fukudo, S1
Chen, KH1
Zeng, BY1
Zeng, BS1
Sun, CK1
Cheng, YS1
Su, KP1
Wu, YC1
Chen, TY1
Lin, PY1
Liang, CS1
Hsu, CW1
Chu, CS1
Chen, YW1
Yeh, PY1
Wu, MK1
Tseng, PT1
Hsu, CY1
Chojnacki, C4
Konrad, P1
Kaczka, A1
Mędrek-Sochab, M1
Chojnacki, M1
Błońska, A1
Faghih Dinevari, M1
Jafarzadeh, F1
Jabbaripour Sarmadian, A1
Abbasian, S1
Nikniaz, Z1
Riazi, A1
Kurin, M1
Cooper, G1
Wang, B1
Zhu, S1
Liu, Z1
Wei, H1
Zhang, L1
He, M1
Pei, F1
Zhang, J1
Sun, Q1
Duan, L1
Ng, QX1
Soh, AYS1
Lim, DY1
Yeo, WS1
Söderquist, F1
Sundberg, I1
Ramklint, M1
Widerström, R1
Hellström, PM1
Cunningham, JL1
Walecka-Kapica, E2
Lokieć, K1
Pawłowicz, M1
Winczyk, K1
Chojnacki, J4
Klupińska, G2
Mokwinska, M1
Romanowski, M1
Pawlowicz, M1
Tan, W1
Zhou, W1
Luo, HS1
Liang, CB1
Xia, H1
Siah, KT1
Wong, RK2
Ho, KY5
Yang, C1
Song, GH3
Wong, J1
Sebastián Domingo, JJ1
Esteban-Zubero, E1
López-Pingarrón, L1
Alatorre-Jiménez, MA1
Ochoa-Moneo, P1
Buisac-Ramón, C1
Rivas-Jiménez, M1
Castán-Ruiz, S1
Antoñanzas-Lombarte, Á1
Tan, DX1
García, JJ1
Reiter, RJ2
Lu, WZ2
Gwee, KA3
Ducrotté, P1
Sood, MR1
Chang, FY1
Lu, CL1
Stepień, A1
Moskwa-Fortuna, A1
Wisniewska-Jarosińska, M2
Harasiuk, A1
Radwan, P1
Skrzydlo-Radomanska, B1
Radwan-Kwiatek, K1
Burak-Czapiuk, B1
Strzemecka, J1
Konturek, S1
Brzozowski, T1
Smigielski, J1
Ghaith, O1
El-Halabi, M1
Hashash, JG1
Sharara, AI1
Mozaffari, S1
Rahimi, R1
Abdollahi, M1
Wilhelmsen, M1
Amirian, I1
Rosenberg, J1
Gögenur, I1
Leng, PH1
Moochhala, SM1
Elsenbruch, S1
Moochhalla, S1
Saha, L1
Malhotra, S1
Rana, S1
Bhasin, D1
Pandhi, P1
Komarov, FI1
Raĭkhlin, NT1
Rapoport, SI1
Malinovskaia, NK1
Voznesenskaia, LA1
Rumiantseva, AI1
Saad, RJ1
Chey, WD1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Understanding the Neurocognitive Effects of Fecal Microbiota Transplantation in Major Depressive Disorder Patients With and Without Irritable Bowel Syndrome[NCT05174273]Phase 2/Phase 3180 participants (Anticipated)Interventional2022-04-06Recruiting
Effects of Perioperative Melatonin on Sleep, Pain, and Confusion After Joint Replacement Surgery[NCT01505465]50 participants (Actual)Interventional2012-02-29Completed
The Therapeutic Effect of Melatonin in Pediatric Patients With Functional Dyspepsia[NCT04684199]14 participants (Actual)Interventional2014-08-31Completed
Exploring the Mechanism of a Probiotic Combination VSL#3 in Irritable Bowel Syndrome: a Randomized Double Blind Placebo Controlled Study[NCT00786123]40 participants (Anticipated)Interventional2006-05-31Completed
Efficacy of Combination Therapy vs Placebo for Pediatric Functional Abdominal Pain[NCT01269671]Phase 10 participants (Actual)Interventional2011-01-31Withdrawn (stopped due to PI has left institution)
Melatonin and Ulcerative Colitis: A Pilot Clinical Trial[NCT00790478]Phase 23 participants (Actual)Interventional2009-01-31Terminated
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Perioperative Sleep Efficiency

Sleep time change from 96 hours before surgery to 72 hours after surgery (NCT01505465)
Timeframe: 96 hours before surgery to 72 hours after surgery

Interventionminutes (Mean)
Study: Melatonin20
Control: Placebo-55

Reviews

9 reviews available for melatonin and Colitis, Mucous

ArticleYear
The efficacy of exogenous melatonin supplement in ameliorating irritable bowel syndrome severity: A meta-analysis of randomized controlled trials.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2023, Volume: 122, Issue:3

    Topics: Dietary Supplements; Humans; Irritable Bowel Syndrome; Melatonin; Pain Measurement; Randomized Contr

2023
Irritable bowel syndrome with diarrhea: Treatment is a work in progress.
    Cleveland Clinic journal of medicine, 2020, Jul-31, Volume: 87, Issue:8

    Topics: Antidepressive Agents; Antidiarrheals; Cognitive Behavioral Therapy; Combined Modality Therapy; Diar

2020
Melatonin for the treatment of irritable bowel syndrome.
    World journal of gastroenterology, 2014, Mar-14, Volume: 20, Issue:10

    Topics: Abdominal Pain; Animals; Dietary Supplements; Gastrointestinal Agents; Humans; Intestinal Mucosa; In

2014
Melatonin's role as a co-adjuvant treatment in colonic diseases: A review.
    Life sciences, 2017, Feb-01, Volume: 170

    Topics: Animals; Cell Proliferation; Colitis; Colitis, Ulcerative; Colonic Diseases; Enterocolitis, Necrotiz

2017
Treatment of irritable bowel syndrome using complementary and alternative medicine.
    Journal of the Chinese Medical Association : JCMA, 2009, Volume: 72, Issue:6

    Topics: Acupuncture Therapy; Aluminum Silicates; Animals; Clay; Complementary Therapies; Humans; Irritable B

2009
Investigational agents for the irritable bowel syndrome.
    Expert opinion on investigational drugs, 2010, Volume: 19, Issue:10

    Topics: Amines; Cyclohexanecarboxylic Acids; Drugs, Investigational; Female; Gabapentin; gamma-Aminobutyric

2010
Implications of melatonin therapy in irritable bowel syndrome: a systematic review.
    Current pharmaceutical design, 2010, Volume: 16, Issue:33

    Topics: Animals; Gastrointestinal Motility; Gastrointestinal Tract; Humans; Irritable Bowel Syndrome; Melato

2010
Analgesic effects of melatonin: a review of current evidence from experimental and clinical studies.
    Journal of pineal research, 2011, Volume: 51, Issue:3

    Topics: Analgesics; Animals; Disease Models, Animal; Fibromyalgia; Humans; Irritable Bowel Syndrome; Male; M

2011
Recent developments in the therapy of irritable bowel syndrome.
    Expert opinion on investigational drugs, 2008, Volume: 17, Issue:2

    Topics: Animals; Antidepressive Agents; Calcium Channel Blockers; Corticotropin-Releasing Hormone; gamma-Ami

2008

Trials

8 trials available for melatonin and Colitis, Mucous

ArticleYear
The effect of melatonin on irritable bowel syndrome patients with and without sleep disorders: a randomized double-blinded placebo-controlled trial study.
    BMC gastroenterology, 2023, Apr-25, Volume: 23, Issue:1

    Topics: Abdominal Pain; Double-Blind Method; Humans; Iran; Irritable Bowel Syndrome; Melatonin; Quality of L

2023
Influence of melatonin on symptoms of irritable bowel syndrome in postmenopausal women.
    Endokrynologia Polska, 2013, Volume: 64, Issue:2

    Topics: Abdominal Pain; Aged; Constipation; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Female;

2013
Influence of tianeptine on melatonin homeostasis and psychosomatic symptoms in patients with irritable bowel syndrome.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2013, Volume: 64, Issue:2

    Topics: Adult; Antidepressive Agents, Tricyclic; Female; Homeostasis; Humans; Irritable Bowel Syndrome; Male

2013
Melatonin regulation as a possible mechanism for probiotic (VSL#3) in irritable bowel syndrome: a randomized double-blinded placebo study.
    Digestive diseases and sciences, 2015, Volume: 60, Issue:1

    Topics: Adult; Aged; Double-Blind Method; Female; Humans; Irritable Bowel Syndrome; Male; Melatonin; Middle

2015
The effects of melatonin on colonic transit time in normal controls and IBS patients.
    Digestive diseases and sciences, 2009, Volume: 54, Issue:5

    Topics: Administration, Oral; Adult; Case-Control Studies; Colon; Cross-Over Studies; Double-Blind Method; F

2009
Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study.
    Gut, 2005, Volume: 54, Issue:10

    Topics: Abdominal Pain; Adult; Defecation; Double-Blind Method; Female; Humans; Irritable Bowel Syndrome; Ma

2005
Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study.
    Gut, 2005, Volume: 54, Issue:10

    Topics: Abdominal Pain; Adult; Defecation; Double-Blind Method; Female; Humans; Irritable Bowel Syndrome; Ma

2005
Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study.
    Gut, 2005, Volume: 54, Issue:10

    Topics: Abdominal Pain; Adult; Defecation; Double-Blind Method; Female; Humans; Irritable Bowel Syndrome; Ma

2005
Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study.
    Gut, 2005, Volume: 54, Issue:10

    Topics: Abdominal Pain; Adult; Defecation; Double-Blind Method; Female; Humans; Irritable Bowel Syndrome; Ma

2005
Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study.
    Gut, 2005, Volume: 54, Issue:10

    Topics: Abdominal Pain; Adult; Defecation; Double-Blind Method; Female; Humans; Irritable Bowel Syndrome; Ma

2005
Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study.
    Gut, 2005, Volume: 54, Issue:10

    Topics: Abdominal Pain; Adult; Defecation; Double-Blind Method; Female; Humans; Irritable Bowel Syndrome; Ma

2005
Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study.
    Gut, 2005, Volume: 54, Issue:10

    Topics: Abdominal Pain; Adult; Defecation; Double-Blind Method; Female; Humans; Irritable Bowel Syndrome; Ma

2005
Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study.
    Gut, 2005, Volume: 54, Issue:10

    Topics: Abdominal Pain; Adult; Defecation; Double-Blind Method; Female; Humans; Irritable Bowel Syndrome; Ma

2005
Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study.
    Gut, 2005, Volume: 54, Issue:10

    Topics: Abdominal Pain; Adult; Defecation; Double-Blind Method; Female; Humans; Irritable Bowel Syndrome; Ma

2005
Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study.
    Gut, 2005, Volume: 54, Issue:10

    Topics: Abdominal Pain; Adult; Defecation; Double-Blind Method; Female; Humans; Irritable Bowel Syndrome; Ma

2005
Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study.
    Gut, 2005, Volume: 54, Issue:10

    Topics: Abdominal Pain; Adult; Defecation; Double-Blind Method; Female; Humans; Irritable Bowel Syndrome; Ma

2005
Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study.
    Gut, 2005, Volume: 54, Issue:10

    Topics: Abdominal Pain; Adult; Defecation; Double-Blind Method; Female; Humans; Irritable Bowel Syndrome; Ma

2005
Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study.
    Gut, 2005, Volume: 54, Issue:10

    Topics: Abdominal Pain; Adult; Defecation; Double-Blind Method; Female; Humans; Irritable Bowel Syndrome; Ma

2005
Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study.
    Gut, 2005, Volume: 54, Issue:10

    Topics: Abdominal Pain; Adult; Defecation; Double-Blind Method; Female; Humans; Irritable Bowel Syndrome; Ma

2005
Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study.
    Gut, 2005, Volume: 54, Issue:10

    Topics: Abdominal Pain; Adult; Defecation; Double-Blind Method; Female; Humans; Irritable Bowel Syndrome; Ma

2005
Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study.
    Gut, 2005, Volume: 54, Issue:10

    Topics: Abdominal Pain; Adult; Defecation; Double-Blind Method; Female; Humans; Irritable Bowel Syndrome; Ma

2005
Melatonin improves bowel symptoms in female patients with irritable bowel syndrome: a double-blind placebo-controlled study.
    Alimentary pharmacology & therapeutics, 2005, Nov-15, Volume: 22, Issue:10

    Topics: Adult; Aged; Anxiety; Depressive Disorder; Double-Blind Method; Female; Gastrointestinal Agents; Hum

2005
A preliminary study of melatonin in irritable bowel syndrome.
    Journal of clinical gastroenterology, 2007, Volume: 41, Issue:1

    Topics: Adolescent; Adult; Aged; Double-Blind Method; Female; Follow-Up Studies; Free Radical Scavengers; Hu

2007

Other Studies

14 other studies available for melatonin and Colitis, Mucous

ArticleYear
Omics profiles of fecal and oral microbiota change in irritable bowel syndrome patients with diarrhea and symptom exacerbation.
    Journal of gastroenterology, 2022, Volume: 57, Issue:10

    Topics: Butyrates; Diarrhea; Fatty Acids, Volatile; Feces; gamma-Aminobutyric Acid; Glutamine; Humans; Hydro

2022
The role of serotonin in pathogenesis of unclassified irritable bowel syndrome.
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2022, Oct-21, Volume: 50, Issue:299

    Topics: Cyproheptadine; Humans; Hydroxyindoleacetic Acid; Irritable Bowel Syndrome; Melatonin; Serotonin

2022
Increased Expression of Colonic Mucosal Melatonin in Patients with Irritable Bowel Syndrome Correlated with Gut Dysbiosis.
    Genomics, proteomics & bioinformatics, 2020, Volume: 18, Issue:6

    Topics: Animals; Diarrhea; Dysbiosis; Humans; Irritable Bowel Syndrome; Melatonin; Rats

2020
Agomelatine, a novel therapeutic option for the management of irritable bowel syndrome.
    Journal of clinical pharmacy and therapeutics, 2018, Volume: 43, Issue:5

    Topics: Acetamides; Adolescent; Adult; Aged; Female; Humans; Hypnotics and Sedatives; Irritable Bowel Syndro

2018
The Relationship Between Daytime Salivary Melatonin and Gastrointestinal Symptoms in Young Adults Seeking Psychiatric Care.
    Psychosomatic medicine, 2019, Volume: 81, Issue:1

    Topics: Adolescent; Adult; Anxiety Disorders; Circadian Rhythm; Comorbidity; Female; Humans; Irritable Bowel

2019
The inhibitory effect of melatonin on colonic motility disorders induced by water avoidance stress in rats.
    European review for medical and pharmacological sciences, 2013, Volume: 17, Issue:22

    Topics: Acetylcholine; Animals; Colon; Defecation; Gastrointestinal Motility; Irritable Bowel Syndrome; Male

2013
[Irritable bowel syndrome: the next-to-last that is being investigated].
    Medicina clinica, 2016, Mar-18, Volume: 146, Issue:6

    Topics: Antidepressive Agents, Tricyclic; Biomarkers; Complementary Therapies; Diet; Dietary Carbohydrates;

2016
[Irritable bowel syndrome: dietary and pharmacological therapeutic options].
    Gastroenterologie clinique et biologique, 2009, Volume: 33 Suppl 1

    Topics: Abdominal Pain; Analgesics; Anesthetics, Local; Anti-Bacterial Agents; Antidepressive Agents; Centra

2009
Treatment approaches to irritable bowel syndrome.
    Pediatric annals, 2009, Volume: 38, Issue:5

    Topics: Alprostadil; Anti-Bacterial Agents; Antidepressive Agents, Tricyclic; Behavior Therapy; Child; Child

2009
[Melatonin secretion and metabolism in patients with irritable bowel syndrome].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2009, Volume: 26, Issue:155

    Topics: Adult; Female; Gastrointestinal Motility; Humans; Irritable Bowel Syndrome; Male; Melatonin; Middle

2009
Is melatonin involved in the irritable bowel syndrome?
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2009, Volume: 60 Suppl 3

    Topics: Adult; Analysis of Variance; Case-Control Studies; Circadian Rhythm; Female; Humans; Irritable Bowel

2009
Evaluation of urinary 6-hydroxymelatonin sulphate excretion in women at different age with irritable bowel syndrome.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2010, Volume: 61, Issue:3

    Topics: Adult; Aged; Female; Humans; Irritable Bowel Syndrome; Melatonin; Middle Aged; Serotonin

2010
Melatonin: a novel treatment for IBS?
    Gut, 2005, Volume: 54, Issue:10

    Topics: Adaptation, Physiological; Humans; Irritable Bowel Syndrome; Melatonin; Mood Disorders; Polysomnogra

2005
[Irritated bowel syndrome: clinicomorphological aspects of treatment with melaxen].
    Klinicheskaia meditsina, 2006, Volume: 84, Issue:11

    Topics: Adjuvants, Immunologic; Adolescent; Adult; Biopsy; Colon; Female; Follow-Up Studies; Humans; Intesti

2006