melatonin has been researched along with Cicatrix, Hypertrophic in 2 studies
Cicatrix, Hypertrophic: An elevated scar, resembling a KELOID, but which does not spread into surrounding tissues. It is formed by enlargement and overgrowth of cicatricial tissue and regresses spontaneously.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Melatonin, an endogenous hormone, can alleviate fibrosis in multiple models of diseases." | 4.84 | Melatonin inhibits fibroblast cell functions and hypertrophic scar formation by enhancing autophagy through the MT2 receptor-inhibited PI3K/Akt /mTOR signaling. ( Cao, X; Chen, C; Chen, M; Deng, W; Dong, Y; Hu, Z; Huang, J; Long, Q; Luo, S; Lv, D; Rong, Y; Tang, B; Wang, H; Xu, Z, 2024) |
| "Melatonin can inhibit proliferation and induce apoptosis of fibroblasts in hypertrophic scar through regulating the gene expressions of cyclin E, p53, and Fas." | 1.37 | [Effect of melatonin on proliferation and apoptosis of fibroblasts in human hypertrophic scar]. ( Dai, LB; Du, GW; Liu, SJ; Xie, YF; Zhang, JC, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dong, Y | 1 |
| Cao, X | 1 |
| Huang, J | 1 |
| Hu, Z | 1 |
| Chen, C | 1 |
| Chen, M | 1 |
| Long, Q | 1 |
| Xu, Z | 1 |
| Lv, D | 1 |
| Rong, Y | 1 |
| Luo, S | 1 |
| Wang, H | 1 |
| Deng, W | 1 |
| Tang, B | 1 |
| Xie, YF | 1 |
| Zhang, JC | 1 |
| Liu, SJ | 1 |
| Dai, LB | 1 |
| Du, GW | 1 |
2 other studies available for melatonin and Cicatrix, Hypertrophic
| Article | Year |
|---|---|
Melatonin inhibits fibroblast cell functions and hypertrophic scar formation by enhancing autophagy through the MT2 receptor-inhibited PI3K/Akt /mTOR signaling.
Topics: Animals; Autophagy; Cicatrix, Hypertrophic; Fibroblasts; Fibrosis; Humans; Melatonin; Phosphatidylin | 2024 |
[Effect of melatonin on proliferation and apoptosis of fibroblasts in human hypertrophic scar].
Topics: Adult; Apoptosis; Cell Proliferation; Cells, Cultured; Cicatrix, Hypertrophic; Cyclin E; fas Recepto | 2011 |