melatonin has been researched along with Chronic Lung Injury in 26 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study investigated the synergistic protective effects of melatonin (MEL) and ascorbic acid (vitamin C, ASA) in treating sepsis-induced lung injury in rats." | 8.31 | Protective effect of melatonin and ascorbic acid combination on sepsis-induced lung injury: An Experimental study. ( Çiçek, B; Demir, Ö; Huyut, MT; Tavacı, T; Üstündağ, H; Yüce, N, 2023) |
| "Inflammation is associated with injury to immature lungs, and melatonin administration to preterm newborns with acute respiratory distress improves pulmonary outcomes." | 7.96 | Melatonin for prevention of fetal lung injury associated with intrauterine inflammation and for improvement of lung maturation. ( Burd, I; Chudnovets, A; Kang, Y; Lee, JY; Lei, J; Na, Q; Shin, HE; Shin, NE; Song, H, 2020) |
| "This study demonstrated that melatonin pretreatment attenuated lung ischaemia-reperfusion injury via inhibition of oxidative stress, inflammation and apoptosis." | 7.88 | Melatonin attenuates lung ischaemia-reperfusion injury via inhibition of oxidative stress and inflammation. ( Wang, JJ; Wang, JS; Wang, ML; Wang, WD; Wei, CH; Zhang, J, 2018) |
| "This study investigated the synergistic protective effects of melatonin (MEL) and ascorbic acid (vitamin C, ASA) in treating sepsis-induced lung injury in rats." | 4.31 | Protective effect of melatonin and ascorbic acid combination on sepsis-induced lung injury: An Experimental study. ( Çiçek, B; Demir, Ö; Huyut, MT; Tavacı, T; Üstündağ, H; Yüce, N, 2023) |
| "Inflammation is associated with injury to immature lungs, and melatonin administration to preterm newborns with acute respiratory distress improves pulmonary outcomes." | 3.96 | Melatonin for prevention of fetal lung injury associated with intrauterine inflammation and for improvement of lung maturation. ( Burd, I; Chudnovets, A; Kang, Y; Lee, JY; Lei, J; Na, Q; Shin, HE; Shin, NE; Song, H, 2020) |
| "This study demonstrated that melatonin pretreatment attenuated lung ischaemia-reperfusion injury via inhibition of oxidative stress, inflammation and apoptosis." | 3.88 | Melatonin attenuates lung ischaemia-reperfusion injury via inhibition of oxidative stress and inflammation. ( Wang, JJ; Wang, JS; Wang, ML; Wang, WD; Wei, CH; Zhang, J, 2018) |
| "The study aims to compare, through histological and biochemical studies, the effects of quercetin, melatonin and their combination in regulation of immuno-inflammatory mediators and heat shock protein expressions in sodium nitrite induced hypoxia in rat lungs." | 3.85 | Original research paper. Pulmonary prophylactic impact of melatonin and/or quercetin: A novel therapy for inflammatory hypoxic stress in rats. ( Al-Rasheed, NM; Attia, HA; Fadda, L; Mohamed, AM; Sharaf, IA, 2017) |
| "The etiology of neonatal lung injury is complicated." | 2.82 | [Research progress on antioxidant mechanism of melatonin in reducing neonatal lung injury]. ( Chen, L; Zhang, Y, 2022) |
| "However, its effects against pulmonary injury promoted by copper are not explored and remain unclear so far." | 1.91 | Melatonin ameliorates chronic copper-induced lung injury. ( Ali, SA; Datusalia, AK; Flora, SJS; Gaun, S; Patwa, J; Singh, P, 2023) |
| "Melatonin (MET) has an anti-radiation effect, but its metabolic period in the body is short." | 1.62 | Protective effect of melatonin entrapped PLGA nanoparticles on radiation-induced lung injury through the miR-21/TGF-β1/Smad3 pathway. ( Gao, J; Hao, Y; He, Y; Li, J; Lu, B; Ran, Y; Shu, C; Wang, S; Zhang, X; Zhao, Y, 2021) |
| "CONCLUSIONS EA could alleviate the lung injury induced by limb ischemia-reperfusion by promoting the secretion of melatonin, while having no effect on the expression of melatonin receptor in lung tissues." | 1.56 | The Role of Melatonin in Electroacupuncture Alleviating Lung Injury Induced by Limb Ischemia-Reperfusion in Rabbits. ( Dong, SA; Gong, LR; Kan, YX; Yu, JB, 2020) |
| "Pulmonary fibrosis is a progressive disease characterized by epithelial cell damage, fibroblast proliferation, excessive extracellular matrix (ECM) deposition, and lung tissue scarring." | 1.51 | Melatonin prevents lung injury by regulating apelin 13 to improve mitochondrial dysfunction. ( Fang, R; Guo, Y; Jin, T; Li, F; Li, Y; Liang, H; Shan, H; Su, X; Wang, Y; Yang, R; Zhang, L; Zhao, X, 2019) |
| "Melatonin was given at 5 or 10 mg/kg/d intraperitoneally, beginning 2 weeks after the start of CCl4 administration." | 1.42 | Melatonin limits the expression of profibrogenic genes and ameliorates the progression of hepatic fibrosis in mice. ( Crespo, I; Fernández, A; González-Gallego, J; Ortiz de Urbina, J; San-Miguel, B; Tuñón, MJ, 2015) |
| "Melatonin (MT) is a hormone that is principally synthesized in the pineal gland." | 1.42 | Melatonin attenuates intestinal ischemia--reperfusion-induced lung injury in rats by upregulating N-myc downstream-regulated gene 2. ( Du, HY; Jiang, T; Ni, YF; Wang, WC; Yang, B; Zhang, H; Zhang, L; Zhang, WD, 2015) |
| "The modification of radiation-induced lung injuries by melatonin was studied by measuring changes in oxidative stress, cytokine expression and histopathology in the lung tissue of mice following irradiation." | 1.39 | Melatonin reduces X-ray radiation-induced lung injury in mice by modulating oxidative stress and cytokine expression. ( Han, JM; Huh, GJ; Jang, SS; Kim, HG; Lee, JS; Park, HJ; Son, CG, 2013) |
| "(2)Melatonin treatment alleviated total hepatic I/R-induced lung injury." | 1.35 | [Total hepatic ischemia-reperfusion-induced lung injury in rats and protective effects of melatonin]. ( Jia, R; Jiang, CL; Yang, BX; Zhao, D, 2008) |
| "Melatonin (MT) has direct and indirect free radical detoxifying activity." | 1.35 | Melatonin protects against oxidative damage in a neonatal rat model of bronchopulmonary dysplasia. ( Fu, JH; Pan, L; Wei, B; Xu, W; Xue, XD; Zhou, P, 2009) |
| "Melatonin was administered at a dose of 100 mg/kg using an intraperitoneal injection." | 1.34 | The histopathological evaluation of the effectiveness of melatonin as a protectant against acute lung injury induced by radiation therapy in a rat model. ( Erkal, HS; Gülbaş, H; Gürses, I; Serin, M; Yücel, N, 2007) |
| "Melatonin was administered i." | 1.31 | Melatonin improves oxidative organ damage in a rat model of thermal injury. ( Keyer-Uysal, M; Satiroğlu, H; Sehirli, AO; Sener, G; Yeğen, BC, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (19.23) | 29.6817 |
| 2010's | 11 (42.31) | 24.3611 |
| 2020's | 10 (38.46) | 2.80 |
| Authors | Studies |
|---|---|
| Bi, W | 1 |
| Bi, Y | 1 |
| Xue, P | 1 |
| Zhang, Y | 2 |
| Gao, X | 1 |
| Wang, Z | 1 |
| Li, M | 1 |
| Baudy-Floc'h, M | 1 |
| Ngerebara, N | 1 |
| Gibson, KM | 1 |
| Bi, L | 1 |
| Gaun, S | 1 |
| Ali, SA | 1 |
| Singh, P | 1 |
| Patwa, J | 1 |
| Flora, SJS | 1 |
| Datusalia, AK | 1 |
| Chen, L | 1 |
| Üstündağ, H | 1 |
| Demir, Ö | 1 |
| Çiçek, B | 1 |
| Huyut, MT | 1 |
| Yüce, N | 1 |
| Tavacı, T | 1 |
| Huo, C | 1 |
| Tang, Y | 1 |
| Li, X | 1 |
| Han, D | 1 |
| Gu, Q | 1 |
| Su, R | 1 |
| Liu, Y | 1 |
| Reiter, RJ | 1 |
| Liu, G | 1 |
| Hu, Y | 1 |
| Yang, H | 1 |
| Li, N | 1 |
| Xiong, R | 1 |
| Li, G | 1 |
| Wang, B | 1 |
| Geng, Q | 1 |
| Han, B | 1 |
| Li, S | 1 |
| Lv, Y | 1 |
| Yang, D | 1 |
| Li, J | 3 |
| Yang, Q | 1 |
| Wu, P | 1 |
| Lv, Z | 1 |
| Zhang, Z | 1 |
| Dong, SA | 1 |
| Gong, LR | 1 |
| Yu, JB | 1 |
| Kan, YX | 1 |
| Lee, JY | 1 |
| Na, Q | 1 |
| Shin, NE | 1 |
| Shin, HE | 1 |
| Kang, Y | 1 |
| Chudnovets, A | 1 |
| Lei, J | 1 |
| Song, H | 1 |
| Burd, I | 1 |
| Wu, Q | 1 |
| Fang, L | 1 |
| Yang, Y | 1 |
| Wang, A | 1 |
| Chen, X | 1 |
| Sun, J | 1 |
| Wan, J | 1 |
| Hong, C | 1 |
| Tong, J | 1 |
| Tao, S | 1 |
| Tian, H | 1 |
| Wang, S | 1 |
| He, Y | 1 |
| Ran, Y | 1 |
| Lu, B | 1 |
| Gao, J | 1 |
| Shu, C | 1 |
| Zhao, Y | 1 |
| Zhang, X | 1 |
| Hao, Y | 1 |
| Guohua, F | 1 |
| Tieyuan, Z | 1 |
| Xinping, M | 1 |
| Juan, X | 1 |
| Wang, ML | 1 |
| Wei, CH | 1 |
| Wang, WD | 1 |
| Wang, JS | 1 |
| Zhang, J | 1 |
| Wang, JJ | 1 |
| Wu, X | 1 |
| Ji, H | 1 |
| Wang, Y | 2 |
| Gu, C | 1 |
| Gu, W | 1 |
| Hu, L | 1 |
| Zhu, L | 1 |
| Zhang, L | 3 |
| Li, F | 1 |
| Su, X | 1 |
| Li, Y | 1 |
| Fang, R | 1 |
| Guo, Y | 1 |
| Jin, T | 1 |
| Shan, H | 2 |
| Zhao, X | 1 |
| Yang, R | 1 |
| Liang, H | 1 |
| Crespo, I | 1 |
| San-Miguel, B | 1 |
| Fernández, A | 1 |
| Ortiz de Urbina, J | 1 |
| González-Gallego, J | 1 |
| Tuñón, MJ | 1 |
| Yang, B | 1 |
| Ni, YF | 1 |
| Wang, WC | 1 |
| Du, HY | 1 |
| Zhang, H | 1 |
| Zhang, WD | 1 |
| Jiang, T | 1 |
| He, D | 1 |
| Shao, Y | 1 |
| Xu, D | 1 |
| Shen, J | 1 |
| Al-Rasheed, NM | 2 |
| Fadda, L | 1 |
| Attia, HA | 1 |
| Sharaf, IA | 1 |
| Mohamed, AM | 1 |
| Jiang, CL | 1 |
| Yang, BX | 1 |
| Zhao, D | 1 |
| Jia, R | 1 |
| Pan, L | 1 |
| Fu, JH | 1 |
| Xue, XD | 1 |
| Xu, W | 1 |
| Zhou, P | 1 |
| Wei, B | 1 |
| Santana-Rodríguez, N | 1 |
| Clavo, B | 1 |
| Llontop, P | 1 |
| López, A | 1 |
| García-Castellano, JM | 1 |
| Machín, RP | 1 |
| Ponce, MA | 1 |
| Fiuza, MD | 1 |
| García-Herrera, R | 1 |
| Brito, Y | 1 |
| Yordi, NA | 1 |
| Chirino, R | 1 |
| Jang, SS | 1 |
| Kim, HG | 1 |
| Lee, JS | 1 |
| Han, JM | 1 |
| Park, HJ | 1 |
| Huh, GJ | 1 |
| Son, CG | 1 |
| Sener, G | 1 |
| Sehirli, AO | 1 |
| Satiroğlu, H | 1 |
| Keyer-Uysal, M | 1 |
| Yeğen, BC | 1 |
| Crisafulli, C | 1 |
| Mazzon, E | 1 |
| Muià, C | 1 |
| Bella, P | 1 |
| Esposito, E | 1 |
| Meli, R | 1 |
| Cuzzocrea, S | 1 |
| Serin, M | 1 |
| Gülbaş, H | 1 |
| Gürses, I | 1 |
| Erkal, HS | 1 |
| Yücel, N | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Apelin; ACE2 and Biomarkers of Alveolar-capillary Permeability in SARS-cov-2 (COVID-19).[NCT04632732] | 140 participants (Actual) | Observational [Patient Registry] | 2020-10-26 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for melatonin and Chronic Lung Injury
| Article | Year |
|---|---|
[Research progress on antioxidant mechanism of melatonin in reducing neonatal lung injury].
Topics: Antioxidants; Humans; Infant, Newborn; Lung; Lung Injury; Melatonin; Oxidative Stress; Pneumonia | 2022 |
25 other studies available for melatonin and Chronic Lung Injury
| Article | Year |
|---|---|
Synthesis and characterization of novel indole derivatives reveal improved therapeutic agents for treatment of ischemia/reperfusion (I/R) injury.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Capillary Permeability; Free Radical | 2010 |
Melatonin ameliorates chronic copper-induced lung injury.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Copper; Female; Inflammation; Lung; Lung Injury; Me | 2023 |
Protective effect of melatonin and ascorbic acid combination on sepsis-induced lung injury: An Experimental study.
Topics: Animals; Antioxidants; Ascorbic Acid; Glutathione; Inflammation; Lung; Lung Injury; Melatonin; Oxida | 2023 |
Melatonin alleviates lung injury in H1N1-infected mice by mast cell inactivation and cytokine storm suppression.
Topics: Animals; Cytokine Release Syndrome; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Lung; | 2023 |
PM2.5 contributed to pulmonary epithelial senescence and ferroptosis by regulating USP3-SIRT3-P53 axis.
Topics: Animals; Cellular Senescence; Ferroptosis; Fibrosis; Lung; Lung Injury; Melatonin; Mice; Particulate | 2023 |
Dietary melatonin attenuates chromium-induced lung injury via activating the Sirt1/Pgc-1α/Nrf2 pathway.
Topics: Animals; Chromium; Dietary Supplements; Humans; Lung Injury; Male; Melatonin; Mice; NF-E2-Related Fa | 2019 |
The Role of Melatonin in Electroacupuncture Alleviating Lung Injury Induced by Limb Ischemia-Reperfusion in Rabbits.
Topics: Animals; Disease Models, Animal; Electroacupuncture; Lung Injury; Melatonin; Rabbits; Reperfusion; R | 2020 |
Melatonin for prevention of fetal lung injury associated with intrauterine inflammation and for improvement of lung maturation.
Topics: Animals; Female; Fetal Diseases; Fetus; Inflammation; Lung; Lung Injury; Melatonin; Mice; Pregnancy | 2020 |
Protection of melatonin against long-term radon exposure-caused lung injury.
Topics: Air Pollutants, Radioactive; Animals; Antioxidants; Apoptosis; Caspase 3; Epithelial Cells; Humans; | 2021 |
Protective effect of melatonin entrapped PLGA nanoparticles on radiation-induced lung injury through the miR-21/TGF-β1/Smad3 pathway.
Topics: Humans; Lung Injury; Melatonin; MicroRNAs; Nanoparticles; Smad3 Protein; Transforming Growth Factor | 2021 |
Melatonin protects against PM2.5-induced lung injury by inhibiting ferroptosis of lung epithelial cells in a Nrf2-dependent manner.
Topics: Animals; Epithelial Cells; Ferroptosis; Kelch-Like ECH-Associated Protein 1; Lung; Lung Injury; Mela | 2021 |
Melatonin attenuates lung ischaemia-reperfusion injury via inhibition of oxidative stress and inflammation.
Topics: Animals; Antioxidants; Apoptosis; Caspase 3; Disease Models, Animal; I-kappa B Kinase; Inflammation; | 2018 |
Melatonin Alleviates Radiation-Induced Lung Injury via Regulation of miR-30e/NLRP3 Axis.
Topics: Animals; Antioxidants; Disease Models, Animal; Humans; Lung Injury; Male; Melatonin; Mice; Mice, Inb | 2019 |
Melatonin prevents lung injury by regulating apelin 13 to improve mitochondrial dysfunction.
Topics: Animals; Apelin; Apoptosis; Bleomycin; Cell Line, Tumor; Cellular Senescence; Epithelial Cells; Lung | 2019 |
Melatonin limits the expression of profibrogenic genes and ameliorates the progression of hepatic fibrosis in mice.
Topics: Actins; Animals; Carbon Tetrachloride; Collagen; Cytokines; Disease Progression; Gene Expression; He | 2015 |
Melatonin attenuates intestinal ischemia--reperfusion-induced lung injury in rats by upregulating N-myc downstream-regulated gene 2.
Topics: Animals; Cytokines; Intestines; Lung; Lung Injury; Male; Malondialdehyde; Melatonin; Nerve Tissue Pr | 2015 |
[Effect of melatonin on p38MAPKsignaling pathway in rats with phosgene-induced lung injury].
Topics: Animals; Bronchoalveolar Lavage Fluid; Chemical Warfare Agents; Imidazoles; Lung; Lung Injury; Male; | 2014 |
Original research paper. Pulmonary prophylactic impact of melatonin and/or quercetin: A novel therapy for inflammatory hypoxic stress in rats.
Topics: Animals; Anti-Inflammatory Agents; Carrier Proteins; Cytoprotection; Disease Models, Animal; Drug Th | 2017 |
[Total hepatic ischemia-reperfusion-induced lung injury in rats and protective effects of melatonin].
Topics: Animals; Extracellular Signal-Regulated MAP Kinases; Liver; Lung Injury; Male; Melatonin; Random All | 2008 |
Melatonin protects against oxidative damage in a neonatal rat model of bronchopulmonary dysplasia.
Topics: Animals; Animals, Newborn; Antioxidants; Catalase; Disease Models, Animal; Glutathione Peroxidase; H | 2009 |
Estradiol worsens the syndrome of ischemia-reperfusion injury in an experimental lung transplantation model.
Topics: Animals; Antioxidants; Chi-Square Distribution; Deferoxamine; Disease Models, Animal; Estradiol; Gra | 2011 |
Melatonin reduces X-ray radiation-induced lung injury in mice by modulating oxidative stress and cytokine expression.
Topics: Animals; Base Sequence; Catalase; Cytokines; Female; Gene Expression; Glutathione; Immunohistochemis | 2013 |
Melatonin improves oxidative organ damage in a rat model of thermal injury.
Topics: Animals; Burns; Disease Models, Animal; Female; Free Radical Scavengers; Intestinal Mucosa; Intestin | 2002 |
Effects of combination of melatonin and dexamethasone on acute lung injury in a mice model of carrageenan-induced pleurisy.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Carrageenan; Dexamethasone; Disease Models, Animal | 2006 |
The histopathological evaluation of the effectiveness of melatonin as a protectant against acute lung injury induced by radiation therapy in a rat model.
Topics: Animals; Gamma Rays; Lung; Lung Injury; Macrophages, Alveolar; Male; Melatonin; Radiation Injuries, | 2007 |