melatonin has been researched along with Chronic Kidney Diseases in 25 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " This review article aimed to present the role of melatonin in this direction, by providing an overview of melatonin's physiology followed by its effect as a therapeutic agent in arterial hypertension and T2DM." | 5.22 | The Role of Melatonin in Chronic Kidney Disease and Its Associated Risk Factors: A New Tool in Our Arsenal? ( Kalaitzidis, RG; Theofilis, P; Vordoni, A, 2022) |
| "The melatonin levels decreased with aging despite not reaching statistical significance, and the decrease was more evident in males than in females (40." | 3.80 | Melatonin and the Charlson Comorbidity Index (CCI): the Treviso Longeva (Trelong) study. ( Albani, D; Boldrini, P; Caberlotto, L; Di Giorgi, E; Durante, E; Flores-Obando, R; Forloni, G; Frigato, A; Gallucci, M; Mazzuco, S; Ongaro, F; Siculi, M; Taioli, E; Zanardo, A, 2014) |
| "Melatonin is a neurohormone that is mainly secreted by the pineal gland." | 3.01 | Melatonin Treatment in Kidney Diseases. ( Markowska, M; Niemczyk, S; Romejko, K, 2023) |
| "Obesity is a common and complex health problem worldwide and can induce the development of Type 2 diabetes." | 2.66 | The roles of melatonin on kidney injury in obese and diabetic conditions. ( Lungkaphin, A; Promsan, S, 2020) |
| "Melatonin is a hormone produced by the pineal gland, predominantly at night, and plays a pivotal role in regulating the circadian rhythm as well as a variety of biological functions, including anti-inflammation, anti-oxidation, inhibition of sympathetic nerve activity, and preservation of endothelial cell function." | 2.61 | The pivotal role of melatonin in ameliorating chronic kidney disease by suppression of the renin-angiotensin system in the kidney. ( Ishigaki, S; Isobe, S; Ohashi, N, 2019) |
| "Treatment with melatonin significantly reversed these abnormalities." | 1.48 | Melatonin ameliorates intrarenal renin-angiotensin system in a 5/6 nephrectomy rat model. ( Fujikura, T; Ishigaki, S; Isobe, S; Iwakura, T; Kato, A; Matsuyama, T; Miyajima, H; Ohashi, N; Tsuji, N; Tsuji, T; Yasuda, H, 2018) |
| "Melatonin is a hormone regulating the circadian rhythm, and has multiple functions such as anti-oxidant and anti-adrenergic effects and enhancement of NO bioavailability." | 1.43 | Impaired endogenous nighttime melatonin secretion relates to intrarenal renin-angiotensin system activation and renal damage in patients with chronic kidney disease. ( Ishigaki, S; Isobe, S; Iwakura, T; Kato, A; Miyajima, H; Ohashi, N; Ono, M; Sakao, Y; Tsuji, N; Tsuji, T; Yasuda, H, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 15 (60.00) | 24.3611 |
| 2020's | 10 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eftekhar Vaghefi, SS | 1 |
| Mousavi, F | 1 |
| Khaksari, M | 1 |
| Asadikaram, G | 1 |
| Soltani, Z | 1 |
| Theofilis, P | 1 |
| Vordoni, A | 1 |
| Kalaitzidis, RG | 1 |
| Markowska, M | 1 |
| Niemczyk, S | 1 |
| Romejko, K | 1 |
| Tang, KS | 1 |
| Ho, CY | 1 |
| Hsu, CN | 1 |
| Tain, YL | 1 |
| Yoon, YM | 3 |
| Lee, JH | 4 |
| Song, KH | 1 |
| Noh, H | 2 |
| Lee, SH | 4 |
| Petrova, A | 1 |
| Kondratiuk, V | 1 |
| Karpenko, O | 1 |
| Ostashevska, T | 1 |
| Krasiuk, E | 1 |
| Promsan, S | 1 |
| Lungkaphin, A | 1 |
| Go, G | 2 |
| Yun, CW | 1 |
| Lim, JH | 2 |
| Movahhed, SMM | 1 |
| Yoon, S | 1 |
| Lee, G | 1 |
| Ishigaki, S | 4 |
| Ohashi, N | 4 |
| Matsuyama, T | 2 |
| Isobe, S | 4 |
| Tsuji, N | 2 |
| Iwakura, T | 2 |
| Fujikura, T | 2 |
| Tsuji, T | 3 |
| Kato, A | 3 |
| Miyajima, H | 2 |
| Yasuda, H | 3 |
| Santamaría, R | 1 |
| Díaz-Tocados, JM | 1 |
| Pendón-Ruiz de Mier, MV | 1 |
| Robles, A | 1 |
| Salmerón-Rodríguez, MD | 1 |
| Ruiz, E | 1 |
| Vergara, N | 1 |
| Aguilera-Tejero, E | 1 |
| Raya, A | 1 |
| Ortega, R | 1 |
| Felsenfeld, A | 1 |
| Muñoz-Castañeda, JR | 1 |
| Martín-Malo, A | 1 |
| Aljama, P | 1 |
| Rodríguez, M | 1 |
| Han, YS | 1 |
| Kim, SM | 1 |
| Jung, SK | 1 |
| Saberi, K | 1 |
| Pasbakhsh, P | 1 |
| Omidi, A | 1 |
| Borhani-Haghighi, M | 1 |
| Nekoonam, S | 1 |
| Omidi, N | 1 |
| Ghasemi, S | 1 |
| Kashani, IR | 1 |
| Sato, T | 1 |
| Nagasawa, Y | 1 |
| Hasuike, Y | 1 |
| Kuragano, T | 1 |
| Ishihara, M | 1 |
| Chen, DQ | 1 |
| Feng, YL | 1 |
| Chen, L | 1 |
| Liu, JR | 1 |
| Wang, M | 1 |
| Vaziri, ND | 1 |
| Zhao, YY | 1 |
| Rahman, A | 1 |
| Hasan, AU | 1 |
| Kobori, H | 1 |
| Hameed, EN | 1 |
| Hadi Al Tukmagi, HF | 1 |
| Allami, HCA | 1 |
| Hrenák, J | 2 |
| Arendášová, K | 1 |
| Rajkovičová, R | 1 |
| Aziriová, S | 2 |
| Repová, K | 2 |
| Krajčírovičová, K | 1 |
| Celec, P | 1 |
| Kamodyová, N | 1 |
| Bárta, A | 1 |
| Adamcová, M | 1 |
| Paulis, L | 2 |
| Simko, F | 2 |
| Gallucci, M | 1 |
| Flores-Obando, R | 1 |
| Mazzuco, S | 1 |
| Ongaro, F | 1 |
| Di Giorgi, E | 1 |
| Boldrini, P | 1 |
| Durante, E | 1 |
| Frigato, A | 1 |
| Albani, D | 1 |
| Forloni, G | 1 |
| Zanardo, A | 1 |
| Siculi, M | 1 |
| Caberlotto, L | 1 |
| Taioli, E | 1 |
| Nagtegaal, EJ | 1 |
| Reiter, RJ | 1 |
| Ono, M | 1 |
| Sakao, Y | 1 |
| Russcher, M | 1 |
| Koch, B | 1 |
| Nagtegaal, E | 1 |
| van der Putten, K | 1 |
| ter Wee, P | 1 |
| Gaillard, C | 1 |
8 reviews available for melatonin and Chronic Kidney Diseases
| Article | Year |
|---|---|
The Role of Melatonin in Chronic Kidney Disease and Its Associated Risk Factors: A New Tool in Our Arsenal?
Topics: Diabetes Mellitus, Type 2; Humans; Hypertension; Melatonin; Renal Insufficiency, Chronic; Renin-Angi | 2022 |
Melatonin Treatment in Kidney Diseases.
Topics: Antioxidants; Humans; Kidney; Melatonin; Quality of Life; Renal Insufficiency, Chronic | 2023 |
Melatonin and Kidney Health: From Fetal Stage to Later Life.
Topics: Animals; Circadian Rhythm; Kidney; Melatonin; Models, Animal; Pineal Gland; Renal Insufficiency, Chr | 2023 |
The roles of melatonin on kidney injury in obese and diabetic conditions.
Topics: Adipocytes; Adipose Tissue; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Cytokines; D | 2020 |
Possible benefits of exogenous melatonin for individuals on dialysis: a narrative review on potential mechanisms and clinical implications.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Humans; Inflammation; Melatonin; Oxidative Stress; | 2021 |
The pivotal role of melatonin in ameliorating chronic kidney disease by suppression of the renin-angiotensin system in the kidney.
Topics: Animals; Antioxidants; Circadian Rhythm; Humans; Hypertension, Renal; Kidney; Melatonin; Renal Insuf | 2019 |
Melatonin and renal protection: novel perspectives from animal experiments and human studies (review).
Topics: Animals; Humans; Kidney; Melatonin; Models, Animal; Renal Insufficiency, Chronic; Signal Transductio | 2015 |
The role of melatonin treatment in chronic kidney disease.
Topics: Blood Pressure; Chronobiology Disorders; Chronotherapy; Humans; Inflammation Mediators; Kidney Failu | 2012 |
1 trial available for melatonin and Chronic Kidney Diseases
| Article | Year |
|---|---|
Melatonin Improves Erythropoietin Hyporesponsiveness via Suppression of Inflammation.
Topics: Anemia; Antioxidants; Biomarkers; Erythropoietin; Female; Hematinics; Humans; Inflammation; Male; Me | 2019 |
16 other studies available for melatonin and Chronic Kidney Diseases
| Article | Year |
|---|---|
Sex-related Changes in Circadian Rhythm of Inflammatory and Oxidative Stress Markers in CKD.
Topics: Animals; Antioxidants; Circadian Rhythm; Female; Humans; Male; Melatonin; Oxidative Stress; Rats; Re | 2021 |
Melatonin-stimulated exosomes enhance the regenerative potential of chronic kidney disease-derived mesenchymal stem/stromal cells via cellular prion proteins.
Topics: Animals; Exosomes; Female; Humans; Male; Melatonin; Mesenchymal Stem Cell Transplantation; Mesenchym | 2020 |
THE EFFECTIVENESS OF MELATONIN IN THE COMPLEX TREATMENT OF HYPERTENSION IN PATIENTS WITH STAGE 5 CHRONIC KIDNEY DISEASE.
Topics: Antihypertensive Agents; Antioxidants; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Centra | 2020 |
Melatonin Suppresses Renal Cortical Fibrosis by Inhibiting Cytoskeleton Reorganization and Mitochondrial Dysfunction through Regulation of miR-4516.
Topics: Animals; Cell Line; Cytoskeleton; Fibrosis; Gene Expression Regulation; Kidney Cortex; Male; Melaton | 2020 |
Melatonin Treatment Improves Renal Fibrosis via miR-4516/SIAH3/PINK1 Axis.
Topics: Animals; Cell Line; Disease Models, Animal; Fibrosis; Humans; Kidney; Kidney Function Tests; Male; M | 2021 |
Melatonin ameliorates intrarenal renin-angiotensin system in a 5/6 nephrectomy rat model.
Topics: Actins; Animals; Antioxidants; Collagen Type I; Disease Models, Animal; Drug Evaluation, Preclinical | 2018 |
Increased Phosphaturia Accelerates The Decline in Renal Function: A Search for Mechanisms.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antioxidants; Cell Line; Female; Glomerular Fil | 2018 |
Melatonin protects chronic kidney disease mesenchymal stem cells against senescence via PrP
Topics: Animals; Blotting, Western; Cell Line, Tumor; Cell Survival; Cellular Senescence; Humans; Immunohist | 2019 |
Melatonin preconditioning of bone marrow-derived mesenchymal stem cells promotes their engraftment and improves renal regeneration in a rat model of chronic kidney disease.
Topics: Animals; Graft Survival; Kidney; Male; Melatonin; Mesenchymal Stem Cell Transplantation; Mesenchymal | 2019 |
Salt Loading Aggravates the Relationship between Melatonin and Proteinuria in Patients with Chronic Kidney Disease.
Topics: Adult; Aged; Albuminuria; Blood Pressure; Body Mass Index; Circadian Rhythm; Female; Humans; Kidney; | 2019 |
Circadian Rhythm and CKD: Is Melatonin a Key Player or Bi-player?
Topics: Circadian Rhythm; Humans; Melatonin; Proteinuria; Renal Insufficiency, Chronic; Sleep | 2019 |
Poricoic acid A enhances melatonin inhibition of AKI-to-CKD transition by regulating Gas6/AxlNFκB/Nrf2 axis.
Topics: Acute Kidney Injury; Animals; Antioxidants; Biomarkers; Gene Expression Regulation; Intercellular Si | 2019 |
Melatonin in chronic kidney disease: a promising chronotherapy targeting the intrarenal renin-angiotensin system.
Topics: Animals; Antioxidants; Chronotherapy; Humans; Kidney; Melatonin; Renal Insufficiency, Chronic; Renin | 2019 |
Protective effect of captopril, olmesartan, melatonin and compound 21 on doxorubicin-induced nephrotoxicity in rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxid | 2013 |
Melatonin and the Charlson Comorbidity Index (CCI): the Treviso Longeva (Trelong) study.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Cardiovascular Diseases; Cohort Studies; Comorbidity; E | 2014 |
Impaired endogenous nighttime melatonin secretion relates to intrarenal renin-angiotensin system activation and renal damage in patients with chronic kidney disease.
Topics: Adult; Aged; Aged, 80 and over; Blood Pressure; Circadian Rhythm; Female; Humans; Kidney; Male; Mela | 2016 |