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melatonin and Chromosome-Defective Micronuclei

melatonin has been researched along with Chromosome-Defective Micronuclei in 6 studies

Research Excerpts

ExcerptRelevanceReference
"Relative to genomic instability, melatonin was effective in reducing DNA damage caused by ageing, presenting antigenotoxic and antimutagenic activities, independently of initiation age."1.56Melatonin supplementation over different time periods until ageing modulates genotoxic parameters in mice. ( Damiani, AP; de Andrade, VM; de Oliveira Sardinha, TT; de Pinho, RA; Gajski, G; Rohr, P; Strapazzon, G, 2020)
"Melatonin (MLT) is an extraordinary antioxidant, which plays an important role in reducing reactive oxygen species (ROS) by scavenging them directly or indirectly."1.48Antigenotoxic effect of melatonin against mercuric chloride in human peripheral blood lymphocytes. ( Patel, TA; Rao, MV, 2018)
"Mitomycin C, which was used as a positive control, also caused the expected large rises in micronuclei in both bone marrow and peripheral blood cells at 24, 48 and 72 h after its administration."1.31Genotoxicity of paraquat: micronuclei induced in bone marrow and peripheral blood are inhibited by melatonin. ( Bitzer-Quintero, OK; García, JJ; Melchiorri, D; Oh, CS; Ortiz, GG; Pablos, MI; Reiter, RJ; Sewerynek, E; Zúñiga, G, 2000)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (50.00)18.2507
2000's1 (16.67)29.6817
2010's1 (16.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Damiani, AP1
Strapazzon, G1
de Oliveira Sardinha, TT1
Rohr, P1
Gajski, G1
de Pinho, RA1
de Andrade, VM1
Patel, TA1
Rao, MV1
Reiter, RJ4
Sewerynek, E2
Poeggeler, B1
Leal, BZ1
Meltz, ML3
Herman, TS2
Ortiz, GG1
Zúñiga, G1
Melchiorri, D1
Pablos, MI1
Oh, CS1
García, JJ1
Bitzer-Quintero, OK1

Other Studies

6 other studies available for melatonin and Chromosome-Defective Micronuclei

ArticleYear
Melatonin supplementation over different time periods until ageing modulates genotoxic parameters in mice.
    Mutagenesis, 2020, 12-31, Volume: 35, Issue:6

    Topics: Aging; Animals; Biomarkers; Comet Assay; Dietary Supplements; DNA Damage; Duration of Therapy; Genom

2020
Antigenotoxic effect of melatonin against mercuric chloride in human peripheral blood lymphocytes.
    Toxicology and industrial health, 2018, Volume: 34, Issue:11

    Topics: Adult; Antioxidants; Chromosome Aberrations; Comet Assay; Humans; Leukocytes, Mononuclear; Male; Mel

2018
Marked reduction of radiation-induced micronuclei in human blood lymphocytes pretreated with melatonin.
    Radiation research, 1995, Volume: 143, Issue:1

    Topics: Cells, Cultured; Dimethyl Sulfoxide; Gamma Rays; Humans; Lymphocytes; Melatonin; Micronuclei, Chromo

1995
Melatonin: possible mechanisms involved in its 'radioprotective' effect.
    Mutation research, 1998, Aug-03, Volume: 404, Issue:1-2

    Topics: Chromosome Aberrations; DNA Damage; Free Radicals; Gamma Rays; Humans; Lymphocytes; Melatonin; Micro

1998
Melatonin and protection from genetic damage in blood and bone marrow: whole-body irradiation studies in mice.
    Journal of pineal research, 1999, Volume: 27, Issue:4

    Topics: Animals; Bone Marrow; DNA Damage; Erythrocytes; Free Radical Scavengers; Gamma Rays; Male; Melatonin

1999
Genotoxicity of paraquat: micronuclei induced in bone marrow and peripheral blood are inhibited by melatonin.
    Mutation research, 2000, Jan-24, Volume: 464, Issue:2

    Topics: Animals; Bone Marrow; Chromosome Breakage; DNA; Erythroblasts; Herbicides; Injections, Intraperitone

2000