melatonin has been researched along with Choriocarcinoma in 4 studies
Choriocarcinoma: A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Results from RT-PCR, western blotting and confocal microscopy demonstrated that the MT1, MT2 and RORalpha1 melatonin receptors are expressed in the human term placental tissues and in choriocarcinoma cell lines JEG-3 and BeWo." | 7.73 | Expression of melatoninergic receptors in human placental choriocarcinoma cell lines. ( Lanoix, D; Ouellette, R; Vaillancourt, C, 2006) |
| "Results from RT-PCR, western blotting and confocal microscopy demonstrated that the MT1, MT2 and RORalpha1 melatonin receptors are expressed in the human term placental tissues and in choriocarcinoma cell lines JEG-3 and BeWo." | 3.73 | Expression of melatoninergic receptors in human placental choriocarcinoma cell lines. ( Lanoix, D; Ouellette, R; Vaillancourt, C, 2006) |
| "Melatonin inhibited thymidine incorporation into human choriocarcinoma JEG-3 cells at physiological and pharmacological concentrations in the present study." | 3.70 | Inhibition of malignant trophoblastic cell proliferation in vitro and in vivo by melatonin. ( Mei, L; Pang, SF; Shiu, SY; Wong, JT; Xi, SC; Xu, JN; Yao, KM, 2000) |
| "Melatonin has protective roles in normal cells and cytotoxic actions in cancer cells, with effects involving autophagy and nuclear factor (erythroid-derived 2)-like 2 (Nrf2) transcription factor pathways." | 1.51 | Melatonin: The smart molecule that differentially modulates autophagy in tumor and normal placental cells. ( Bienvenue-Pariseault, J; Sagrillo-Fagundes, L; Vaillancourt, C, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sagrillo-Fagundes, L | 1 |
| Bienvenue-Pariseault, J | 1 |
| Vaillancourt, C | 2 |
| Lanoix, D | 1 |
| Ouellette, R | 1 |
| Shiu, SY | 2 |
| Li, L | 1 |
| Xu, JN | 2 |
| Pang, CS | 1 |
| Wong, JT | 2 |
| Pang, SF | 2 |
| Xi, SC | 1 |
| Mei, L | 1 |
| Yao, KM | 1 |
4 other studies available for melatonin and Choriocarcinoma
| Article | Year |
|---|---|
Melatonin: The smart molecule that differentially modulates autophagy in tumor and normal placental cells.
Topics: Apoptosis; Autophagy; Cell Line, Tumor; Choriocarcinoma; Female; Humans; Melatonin; Neoplasm Protein | 2019 |
Expression of melatoninergic receptors in human placental choriocarcinoma cell lines.
Topics: Cell Line, Tumor; Choriocarcinoma; Chorionic Gonadotropin, beta Subunit, Human; Female; Fluorescent | 2006 |
Melatonin-induced inhibition of proliferation and G1/S cell cycle transition delay of human choriocarcinoma JAr cells: possible involvement of MT2 (MEL1B) receptor.
Topics: Cell Division; Choriocarcinoma; Epididymis; Epithelial Cells; G1 Phase; Humans; In Situ Hybridizatio | 1999 |
Inhibition of malignant trophoblastic cell proliferation in vitro and in vivo by melatonin.
Topics: Animals; Cell Division; Cell Survival; Choriocarcinoma; Female; Gene Expression Regulation, Neoplast | 2000 |