Page last updated: 2024-10-19

melatonin and Cholangiocarcinoma

melatonin has been researched along with Cholangiocarcinoma in 5 studies

Cholangiocarcinoma: A malignant tumor arising from the epithelium of the BILE DUCTS.

Research Excerpts

ExcerptRelevanceReference
"We previously demonstrated that melatonin could be used as a chemopreventive agent for inhibiting cholangiocarcinoma (CCA) development in a hamster model."7.81Melatonin induces apoptosis in cholangiocarcinoma cell lines by activating the reactive oxygen species-mediated mitochondrial pathway. ( Hiraku, Y; Intuyod, K; Laothong, U; Murata, M; Oikawa, S; Pinlaor, S, 2015)
"Melatonin treatment at 50 mg/kg caused a significant reduction in liver/body weight ratios and decreased tumor volumes leading to an increase in the survival of animals."5.39Melatonin inhibits cholangiocarcinoma and reduces liver injury in Opisthorchis viverrini-infected and N-nitrosodimethylamine-treated hamsters. ( Boonsiri, P; Charoensuk, L; Intuyod, K; Johns, NP; Laothong, U; Pairojkul, C; Pinlaor, P; Pinlaor, S; Priprem, A, 2013)
"Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy."4.40Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023)
"We previously demonstrated that melatonin could be used as a chemopreventive agent for inhibiting cholangiocarcinoma (CCA) development in a hamster model."3.81Melatonin induces apoptosis in cholangiocarcinoma cell lines by activating the reactive oxygen species-mediated mitochondrial pathway. ( Hiraku, Y; Intuyod, K; Laothong, U; Murata, M; Oikawa, S; Pinlaor, S, 2015)
"Melatonin (50mg/kg) was additionally administered to one group for the 30days of the experiment."1.48Melatonin suppresses eosinophils and Th17 cells in hamsters treated with a combination of human liver fluke infection and a chemical carcinogen. ( Charoensuk, L; Dangtakot, R; Intuyod, K; Pinlaor, P; Pinlaor, S; Wongsena, W, 2018)
"Melatonin treatment at 50 mg/kg caused a significant reduction in liver/body weight ratios and decreased tumor volumes leading to an increase in the survival of animals."1.39Melatonin inhibits cholangiocarcinoma and reduces liver injury in Opisthorchis viverrini-infected and N-nitrosodimethylamine-treated hamsters. ( Boonsiri, P; Charoensuk, L; Intuyod, K; Johns, NP; Laothong, U; Pairojkul, C; Pinlaor, P; Pinlaor, S; Priprem, A, 2013)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Wongsena, W1
Charoensuk, L2
Dangtakot, R1
Pinlaor, P2
Intuyod, K3
Pinlaor, S3
Laothong, U2
Boonsiri, P1
Pairojkul, C1
Priprem, A1
Johns, NP1
Hiraku, Y1
Oikawa, S1
Murata, M1
Han, Y1
Demorrow, S1
Invernizzi, P1
Jing, Q1
Glaser, S1
Renzi, A1
Meng, F1
Venter, J1
Bernuzzi, F1
White, M1
Francis, H1
Lleo, A1
Marzioni, M1
Onori, P1
Alvaro, D1
Torzilli, G1
Gaudio, E1
Alpini, G1

Reviews

1 review available for melatonin and Cholangiocarcinoma

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023

Trials

1 trial available for melatonin and Cholangiocarcinoma

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023

Other Studies

4 other studies available for melatonin and Cholangiocarcinoma

ArticleYear
Melatonin suppresses eosinophils and Th17 cells in hamsters treated with a combination of human liver fluke infection and a chemical carcinogen.
    Pharmacological reports : PR, 2018, Volume: 70, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Bile Duct Neoplasms; Cholangiocarcinoma; Cricetinae; Cytokines; Di

2018
Melatonin inhibits cholangiocarcinoma and reduces liver injury in Opisthorchis viverrini-infected and N-nitrosodimethylamine-treated hamsters.
    Journal of pineal research, 2013, Volume: 55, Issue:3

    Topics: Animals; Antioxidants; Cholangiocarcinoma; Cricetinae; Dimethylnitrosamine; DNA Fragmentation; DNA,

2013
Melatonin induces apoptosis in cholangiocarcinoma cell lines by activating the reactive oxygen species-mediated mitochondrial pathway.
    Oncology reports, 2015, Volume: 33, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Antioxidants; Apoptosis; Bile Duct Neoplasms; Bile Ducts, Intrahepatic;

2015
Melatonin exerts by an autocrine loop antiproliferative effects in cholangiocarcinoma: its synthesis is reduced favoring cholangiocarcinoma growth.
    American journal of physiology. Gastrointestinal and liver physiology, 2011, Volume: 301, Issue:4

    Topics: Acetylserotonin O-Methyltransferase; Animals; Apoptosis; Arylalkylamine N-Acetyltransferase; Autocri

2011