Page last updated: 2024-10-19

melatonin and Child Mental Disorders

melatonin has been researched along with Child Mental Disorders in 12 studies

Research Excerpts

ExcerptRelevanceReference
" We will include randomised clinical trials comparing melatonin versus placebo or no intervention for sleep disorders in children with neurodevelopmental disorders."9.51Melatonin for sleep disorders in children with neurodevelopmental disorders: protocol for a systematic review with meta-analysis and Trial Sequential Analysis of randomised clinical trials. ( Faltermeier, P; Gluud, C; Hermann, R; Horowitz, M; Jakobsen, JC; Juul, S; Jørgensen, CK; Moncrieff, J, 2022)
"Clinical evidence is required about the long-term efficacy and safety of melatonin treatment for sleep problems in children with neurodevelopmental disorders (NDDs) who underwent adequate sleep hygiene interventions."9.34Long-term melatonin treatment for the sleep problems and aberrant behaviors of children with neurodevelopmental disorders. ( Hamada, I; Hayashi, M; Ishikawa, Y; Mishima, K; Nagamitsu, S; Sugioka, H; Takahashi, H; Yamashita, Y; Yotsuya, O; Yuge, K, 2020)
"To determine the efficacy and safety of melatonin as therapy for sleep problems in children with neurodevelopmental disorders."8.98Melatonin for the management of sleep problems in children with neurodevelopmental disorders: a systematic review and meta-analysis. ( Abdelgadir, IS; Akobeng, AK; Gordon, MA, 2018)
"7 years) with neurodevelopmental disorders (n = 29: intellectual disability; n = 9: autism spectrum disorder; n = 7: attention-deficit/hyperactivity disorder) and sleep disturbances, treated with melatonin (mean duration: 326 days) with doses increased according to response."7.81Melatonin for sleep disturbance in children with neurodevelopmental disorders: prospective observational naturalistic study. ( Ayyash, HF; Cortese, S; Morton, R; Preece, P, 2015)
" We will include randomised clinical trials comparing melatonin versus placebo or no intervention for sleep disorders in children with neurodevelopmental disorders."5.51Melatonin for sleep disorders in children with neurodevelopmental disorders: protocol for a systematic review with meta-analysis and Trial Sequential Analysis of randomised clinical trials. ( Faltermeier, P; Gluud, C; Hermann, R; Horowitz, M; Jakobsen, JC; Juul, S; Jørgensen, CK; Moncrieff, J, 2022)
"Children with neurodevelopmental disorders are at risk of sleep problems, typically difficulty getting to sleep, sleep/wake rhythm disturbances and reduced duration of sleep (insomnia)."5.42Melatonin for sleep problems in children with neurodevelopmental disorders. ( , 2015)
"Clinical evidence is required about the long-term efficacy and safety of melatonin treatment for sleep problems in children with neurodevelopmental disorders (NDDs) who underwent adequate sleep hygiene interventions."5.34Long-term melatonin treatment for the sleep problems and aberrant behaviors of children with neurodevelopmental disorders. ( Hamada, I; Hayashi, M; Ishikawa, Y; Mishima, K; Nagamitsu, S; Sugioka, H; Takahashi, H; Yamashita, Y; Yotsuya, O; Yuge, K, 2020)
"To determine the efficacy and safety of melatonin as therapy for sleep problems in children with neurodevelopmental disorders."4.98Melatonin for the management of sleep problems in children with neurodevelopmental disorders: a systematic review and meta-analysis. ( Abdelgadir, IS; Akobeng, AK; Gordon, MA, 2018)
"7 years) with neurodevelopmental disorders (n = 29: intellectual disability; n = 9: autism spectrum disorder; n = 7: attention-deficit/hyperactivity disorder) and sleep disturbances, treated with melatonin (mean duration: 326 days) with doses increased according to response."3.81Melatonin for sleep disturbance in children with neurodevelopmental disorders: prospective observational naturalistic study. ( Ayyash, HF; Cortese, S; Morton, R; Preece, P, 2015)
" However, there is still uncertainty concerning dosing regimens and a lack of other data."2.61Pediatric sleep disturbances and treatment with melatonin. ( Argentiero, A; D'Alonzo, R; Di Genova, L; Esposito, S; Fattorusso, A; Laino, D; Mencarelli, A; Mencaroni, E, 2019)
"Children with neurodevelopmental disorders are at risk of sleep problems, typically difficulty getting to sleep, sleep/wake rhythm disturbances and reduced duration of sleep (insomnia)."1.42Melatonin for sleep problems in children with neurodevelopmental disorders. ( , 2015)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (58.33)24.3611
2020's5 (41.67)2.80

Authors

AuthorsStudies
Salanitro, M1
Wrigley, T1
Ghabra, H1
de Haan, E1
Hill, CM1
Solmi, M1
Cortese, S2
Dack, R1
Garstang, JJ1
Jørgensen, CK3
Hermann, R3
Juul, S3
Faltermeier, P3
Horowitz, M3
Moncrieff, J3
Gluud, C3
Jakobsen, JC3
Bruni, O1
Angriman, M1
Melegari, MG1
Ferri, R1
Yuge, K1
Nagamitsu, S1
Ishikawa, Y1
Hamada, I1
Takahashi, H1
Sugioka, H1
Yotsuya, O1
Mishima, K1
Hayashi, M1
Yamashita, Y1
Woodford, EC1
McLay, L1
France, KG1
Blampied, NM1
Gibbs, R1
Swan, CE1
Eggleston, M1
Abdelgadir, IS1
Gordon, MA1
Akobeng, AK1
Smith, ACM1
Morse, RS1
Introne, W1
Duncan, WC1
Esposito, S1
Laino, D1
D'Alonzo, R1
Mencarelli, A1
Di Genova, L1
Fattorusso, A1
Argentiero, A1
Mencaroni, E1
Ayyash, HF1
Preece, P1
Morton, R1
Waldron, AY1
Spark, MJ1
Dennis, CM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase II/III Clinical Trial of NPC-15 - Verification of the Efficacy for Sleep Disorders of Children With Autism Spectrum Disorders -[NCT02757066]Phase 2/Phase 3196 participants (Actual)Interventional2016-06-16Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for melatonin and Child Mental Disorders

ArticleYear
Efficacy on sleep parameters and tolerability of melatonin in individuals with sleep or mental disorders: A systematic review and meta-analysis.
    Neuroscience and biobehavioral reviews, 2022, Volume: 139

    Topics: Adolescent; Child; Humans; Melatonin; Neurodevelopmental Disorders; Sleep; Sleep Wake Disorders

2022
Pharmacotherapeutic management of sleep disorders in children with neurodevelopmental disorders.
    Expert opinion on pharmacotherapy, 2019, Volume: 20, Issue:18

    Topics: Antidepressive Agents; Antipsychotic Agents; Child; Dietary Supplements; Humans; Hypnotics and Sedat

2019
Endogenous melatonin and sleep in individuals with Rare Genetic Neurodevelopmental Disorders (RGND): A systematic review.
    Sleep medicine reviews, 2021, Volume: 57

    Topics: Humans; Melatonin; Neurodevelopmental Disorders; Sleep; Sleep Wake Disorders; Smith-Magenis Syndrome

2021
Melatonin for the management of sleep problems in children with neurodevelopmental disorders: a systematic review and meta-analysis.
    Archives of disease in childhood, 2018, Volume: 103, Issue:12

    Topics: Central Nervous System Depressants; Child; Humans; Melatonin; Models, Statistical; Neurodevelopmenta

2018
Pediatric sleep disturbances and treatment with melatonin.
    Journal of translational medicine, 2019, 03-12, Volume: 17, Issue:1

    Topics: Child; Child Behavior; Humans; Melatonin; Mental Disorders; Neurodevelopmental Disorders; Sleep Wake

2019

Trials

2 trials available for melatonin and Child Mental Disorders

ArticleYear
Melatonin for sleep disorders in children with neurodevelopmental disorders: protocol for a systematic review with meta-analysis and Trial Sequential Analysis of randomised clinical trials.
    BMJ open, 2022, 11-29, Volume: 12, Issue:11

    Topics: Child; Drug-Related Side Effects and Adverse Reactions; Humans; Melatonin; Meta-Analysis as Topic; N

2022
Melatonin for sleep disorders in children with neurodevelopmental disorders: protocol for a systematic review with meta-analysis and Trial Sequential Analysis of randomised clinical trials.
    BMJ open, 2022, 11-29, Volume: 12, Issue:11

    Topics: Child; Drug-Related Side Effects and Adverse Reactions; Humans; Melatonin; Meta-Analysis as Topic; N

2022
Melatonin for sleep disorders in children with neurodevelopmental disorders: protocol for a systematic review with meta-analysis and Trial Sequential Analysis of randomised clinical trials.
    BMJ open, 2022, 11-29, Volume: 12, Issue:11

    Topics: Child; Drug-Related Side Effects and Adverse Reactions; Humans; Melatonin; Meta-Analysis as Topic; N

2022
Melatonin for sleep disorders in children with neurodevelopmental disorders: protocol for a systematic review with meta-analysis and Trial Sequential Analysis of randomised clinical trials.
    BMJ open, 2022, 11-29, Volume: 12, Issue:11

    Topics: Child; Drug-Related Side Effects and Adverse Reactions; Humans; Melatonin; Meta-Analysis as Topic; N

2022
Long-term melatonin treatment for the sleep problems and aberrant behaviors of children with neurodevelopmental disorders.
    BMC psychiatry, 2020, 09-10, Volume: 20, Issue:1

    Topics: Adolescent; Autism Spectrum Disorder; Child; Female; Humans; Japan; Male; Melatonin; Neurodevelopmen

2020

Other Studies

5 other studies available for melatonin and Child Mental Disorders

ArticleYear
Use of melatonin: a single-centre audit.
    BMJ paediatrics open, 2022, Volume: 6, Issue:1

    Topics: Adolescent; Autism Spectrum Disorder; Child; Humans; Melatonin; Neurodevelopmental Disorders; Sleep

2022
Twenty-four-hour motor activity and body temperature patterns suggest altered central circadian timekeeping in Smith-Magenis syndrome, a neurodevelopmental disorder.
    American journal of medical genetics. Part A, 2019, Volume: 179, Issue:2

    Topics: Adolescent; Adult; Body Temperature; Child; Chromosomes, Human, Pair 17; Circadian Clocks; Circadian

2019
Melatonin for sleep disturbance in children with neurodevelopmental disorders: prospective observational naturalistic study.
    Expert review of neurotherapeutics, 2015, Volume: 15, Issue:6

    Topics: Analysis of Variance; Central Nervous System Depressants; Child; Child, Preschool; Dose-Response Rel

2015
Melatonin for sleep problems in children with neurodevelopmental disorders.
    Drug and therapeutics bulletin, 2015, Volume: 53, Issue:10

    Topics: Attention Deficit Disorder with Hyperactivity; Autism Spectrum Disorder; Child; Humans; Hypnotics an

2015
The Use of Melatonin by Children: Parents' Perspectives.
    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2016, 10-15, Volume: 12, Issue:10

    Topics: Adolescent; Attitude to Health; Australia; Central Nervous System Depressants; Child; Child, Prescho

2016