Page last updated: 2024-10-19

melatonin and Cerebral Palsy

melatonin has been researched along with Cerebral Palsy in 7 studies

Cerebral Palsy: A heterogeneous group of nonprogressive motor disorders caused by chronic brain injuries that originate in the prenatal period, perinatal period, or first few years of life. The four major subtypes are spastic, athetoid, ataxic, and mixed cerebral palsy, with spastic forms being the most common. The motor disorder may range from difficulties with fine motor control to severe spasticity (see MUSCLE SPASTICITY) in all limbs. Spastic diplegia (Little disease) is the most common subtype, and is characterized by spasticity that is more prominent in the legs than in the arms. Pathologically, this condition may be associated with LEUKOMALACIA, PERIVENTRICULAR. (From Dev Med Child Neurol 1998 Aug;40(8):520-7)

Research Excerpts

ExcerptRelevanceReference
" This review details the adverse effects of IUGR on fetal brain development and discusses intervention strategies."2.53Neurodevelopment in children with intrauterine growth restriction: adverse effects and interventions. ( Fu, W; Liu, J; Wang, Y, 2016)
"The literature describes sleep disorders as common in both conditions."2.48Interventions with a sleep outcome for children with cerebral palsy or a post-traumatic brain injury: a systematic review. ( Elder, DE; Galland, BC; Taylor, BJ, 2012)
"Periventricular leukomalacia is one of the main causes of cerebral palsy."1.31Melatoninergic neuroprotection of the murine periventricular white matter against neonatal excitotoxic challenge. ( Bac, P; Evrard, P; Gressens, P; Husson, I; Mesplès, B; Vamecq, J, 2002)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's5 (71.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Santos, JS1
Giacheti, CM1
Dornelas, LS1
Silva, NC1
Souza, ALDM1
Guissoni Campos, LM1
Pinato, L1
Albrecht, M1
Zitta, K1
Groenendaal, F1
van Bel, F1
Peeters-Scholte, C1
Wang, Y1
Fu, W1
Liu, J1
McAdams, RM1
Juul, SE1
Galland, BC1
Elder, DE1
Taylor, BJ1
Baxter, P1
Husson, I1
Mesplès, B1
Bac, P1
Vamecq, J1
Evrard, P1
Gressens, P1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Autophagy, Mitophagy, Inflammation and Plasmatic Concentration of Melatonin in Newborn With Metabolic Acidosis at Birth[NCT03897101]150 participants (Anticipated)Observational [Patient Registry]2019-03-01Recruiting
Use of Melatonin for Neuroprotection in Term Infants With Hypoxic-ischaemic Encephalopathy[NCT03806816]100 participants (Anticipated)Interventional2018-12-13Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for melatonin and Cerebral Palsy

ArticleYear
Neuroprotective strategies following perinatal hypoxia-ischemia: Taking aim at NOS.
    Free radical biology & medicine, 2019, Volume: 142

    Topics: Allopurinol; Asphyxia Neonatorum; Biotin; Cerebral Palsy; Clinical Trials as Topic; Epilepsy; Erythr

2019
Neurodevelopment in children with intrauterine growth restriction: adverse effects and interventions.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2016, Volume: 29, Issue:4

    Topics: Adult; Antioxidants; Brain; Cerebral Palsy; Child; Cognition Disorders; Depression; Developmental Di

2016
Neonatal Encephalopathy: Update on Therapeutic Hypothermia and Other Novel Therapeutics.
    Clinics in perinatology, 2016, Volume: 43, Issue:3

    Topics: Anesthetics, Inhalation; Biotin; Central Nervous System Depressants; Cerebral Palsy; Constriction; E

2016
Neonatal Encephalopathy: Update on Therapeutic Hypothermia and Other Novel Therapeutics.
    Clinics in perinatology, 2016, Volume: 43, Issue:3

    Topics: Anesthetics, Inhalation; Biotin; Central Nervous System Depressants; Cerebral Palsy; Constriction; E

2016
Neonatal Encephalopathy: Update on Therapeutic Hypothermia and Other Novel Therapeutics.
    Clinics in perinatology, 2016, Volume: 43, Issue:3

    Topics: Anesthetics, Inhalation; Biotin; Central Nervous System Depressants; Cerebral Palsy; Constriction; E

2016
Neonatal Encephalopathy: Update on Therapeutic Hypothermia and Other Novel Therapeutics.
    Clinics in perinatology, 2016, Volume: 43, Issue:3

    Topics: Anesthetics, Inhalation; Biotin; Central Nervous System Depressants; Cerebral Palsy; Constriction; E

2016
Interventions with a sleep outcome for children with cerebral palsy or a post-traumatic brain injury: a systematic review.
    Sleep medicine reviews, 2012, Volume: 16, Issue:6

    Topics: Brain Injuries; Cerebral Palsy; Child; Child, Preschool; Humans; Hypnotics and Sedatives; Infant; Me

2012

Other Studies

3 other studies available for melatonin and Cerebral Palsy

ArticleYear
Day/night melatonin content in cerebral palsy.
    Neuroscience letters, 2018, 11-01, Volume: 686

    Topics: Adolescent; Cerebral Palsy; Child; Child, Preschool; Circadian Rhythm; Female; Humans; Male; Melaton

2018
Evidence based medicine.
    Developmental medicine and child neurology, 2004, Volume: 46, Issue:11

    Topics: Adaptation, Psychological; Capital Financing; Cerebral Palsy; Child; Epilepsy; Evidence-Based Medici

2004
Melatoninergic neuroprotection of the murine periventricular white matter against neonatal excitotoxic challenge.
    Annals of neurology, 2002, Volume: 51, Issue:1

    Topics: Animals; Animals, Newborn; Antioxidants; Cell Death; Cerebral Palsy; Cystine; Denervation; Disease M

2002