melatonin has been researched along with Cerebral Hemorrhage in 16 studies
Cerebral Hemorrhage: Bleeding into one or both CEREBRAL HEMISPHERES including the BASAL GANGLIA and the CEREBRAL CORTEX. It is often associated with HYPERTENSION and CRANIOCEREBRAL TRAUMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In one study, higher serum melatonin levels have been reported at diagnosis of spontaneous intracerebral hemorrhage (ICH) in non-surviving than in surviving patients." | 8.12 | Mortality prediction by serum melatonin levels of patients with spontaneous intracerebral hemorrhage. ( Abreu-González, P; Argueso, M; Cáceres, JJ; Jiménez, A; Lorente, L; Martín, MM; Ramos-Gómez, L; Solé-Violán, J, 2022) |
| "This study sought to investigate a novel effect of melatonin in reducing brain injury in an in vivo hyperglycemic intracerebral hemorrhage (ICH) model and further explore the mechanisms of protection." | 7.96 | Melatonin Alleviates Neuronal Damage After Intracerebral Hemorrhage in Hyperglycemic Rats. ( Liang, F; Shi, L; Sun, Z; Wang, J; Wang, Z; Xu, S; Zhang, J; Zheng, J; Zhou, J; Zhu, X, 2020) |
| "Since free radicals play a role in the mechanisms of brain injury after hemorrhagic stroke, the effect of melatonin (a potent antioxidant and free-radical scavenger) on outcomes was investigated after intracerebral hemorrhage (ICH) in rats." | 7.76 | Protective effect of melatonin upon neuropathology, striatal function, and memory ability after intracerebral hemorrhage in rats. ( Ayer, R; Chen, W; Hartman, R; Lekic, T; Manaenko, A; Rojas, H; Tang, J; Zhang, JH, 2010) |
| "The study was performed to investigate the effect of combination therapy with melatonin and dexamethasone (DEX) on brain injury in intracerebral hemorrhage (ICH) model in rats." | 7.75 | Effects of combination treatment of dexamethasone and melatonin on brain injury in intracerebral hemorrhage model in rats. ( Li, ZQ; Liang, GB; Liu, YH; Xue, YX, 2009) |
| " Since melatonin is a potent free radical scavenger and indirect antioxidant, the objective of this study was to evaluate whether melatonin administration would attenuate oxidative stress, brain edema, and neurological deficits in a rat model of ICH." | 7.74 | The antioxidant effects of melatonin after intracerebral hemorrhage in rats. ( Chen, W; Jadhav, V; Lekic, T; Martin, RD; Rojas, H; Tang, J; Titova, E; Zhang, J, 2008) |
| "The diurnal rhythm of plasma melatonin was studied in 46 Chinese patients with acute cerebral hemorrhage." | 7.68 | Acute cerebral hemorrhage changes the nocturnal surge of plasma melatonin in humans. ( Chang, B; Jiang, DH; Li, Y; Pang, SF; Xie, BL, 1990) |
| "Melatonin is a potent antioxidant and anti-inflammatory agent that is showing promising results in acute brain injury." | 6.72 | Efficacy of melatonin in animal models of intracerebral hemorrhage: a systematic review and meta-analysis. ( Chen, C; Hu, X; Hu, Z; Qin, H; Tang, J; Zeng, L; Zhu, Y, 2021) |
| "Improvements in encephalopathy and medical stabilization did not rapidly normalize rhythms." | 5.56 | Factors Disrupting Melatonin Secretion Rhythms During Critical Illness. ( Abbott, SM; Eed, J; Gendy, M; Liotta, EM; Lizza, BD; Maas, MB; Naidech, AM; Reid, KJ; Zee, PC, 2020) |
| "Melatonin (15 mg/kg) was administered by intraperitoneal injection at 1, 24, 48, and 72 h." | 5.35 | Long-term effects of melatonin after intracerebral hemorrhage in rats. ( Ayer, R; Hartman, RE; Jadhav, V; Lee, S; Lekic, T; Rojas, HA; Tang, J; Titova, E; Zhang, JH, 2008) |
| "In one study, higher serum melatonin levels have been reported at diagnosis of spontaneous intracerebral hemorrhage (ICH) in non-surviving than in surviving patients." | 4.12 | Mortality prediction by serum melatonin levels of patients with spontaneous intracerebral hemorrhage. ( Abreu-González, P; Argueso, M; Cáceres, JJ; Jiménez, A; Lorente, L; Martín, MM; Ramos-Gómez, L; Solé-Violán, J, 2022) |
| "This study sought to investigate a novel effect of melatonin in reducing brain injury in an in vivo hyperglycemic intracerebral hemorrhage (ICH) model and further explore the mechanisms of protection." | 3.96 | Melatonin Alleviates Neuronal Damage After Intracerebral Hemorrhage in Hyperglycemic Rats. ( Liang, F; Shi, L; Sun, Z; Wang, J; Wang, Z; Xu, S; Zhang, J; Zheng, J; Zhou, J; Zhu, X, 2020) |
| "Since free radicals play a role in the mechanisms of brain injury after hemorrhagic stroke, the effect of melatonin (a potent antioxidant and free-radical scavenger) on outcomes was investigated after intracerebral hemorrhage (ICH) in rats." | 3.76 | Protective effect of melatonin upon neuropathology, striatal function, and memory ability after intracerebral hemorrhage in rats. ( Ayer, R; Chen, W; Hartman, R; Lekic, T; Manaenko, A; Rojas, H; Tang, J; Zhang, JH, 2010) |
| "The study was performed to investigate the effect of combination therapy with melatonin and dexamethasone (DEX) on brain injury in intracerebral hemorrhage (ICH) model in rats." | 3.75 | Effects of combination treatment of dexamethasone and melatonin on brain injury in intracerebral hemorrhage model in rats. ( Li, ZQ; Liang, GB; Liu, YH; Xue, YX, 2009) |
| " Since melatonin is a potent free radical scavenger and indirect antioxidant, the objective of this study was to evaluate whether melatonin administration would attenuate oxidative stress, brain edema, and neurological deficits in a rat model of ICH." | 3.74 | The antioxidant effects of melatonin after intracerebral hemorrhage in rats. ( Chen, W; Jadhav, V; Lekic, T; Martin, RD; Rojas, H; Tang, J; Titova, E; Zhang, J, 2008) |
| "The diurnal rhythm of plasma melatonin was studied in 46 Chinese patients with acute cerebral hemorrhage." | 3.68 | Acute cerebral hemorrhage changes the nocturnal surge of plasma melatonin in humans. ( Chang, B; Jiang, DH; Li, Y; Pang, SF; Xie, BL, 1990) |
| "Melatonin is a potent antioxidant and anti-inflammatory agent that is showing promising results in acute brain injury." | 2.72 | Efficacy of melatonin in animal models of intracerebral hemorrhage: a systematic review and meta-analysis. ( Chen, C; Hu, X; Hu, Z; Qin, H; Tang, J; Zeng, L; Zhu, Y, 2021) |
| "Stroke is the second leading cause of death worldwide, estimated that one-sixth of the world population will suffer it once in their life." | 2.72 | Blood-brain barrier dysfunction in hemorrhagic transformation: a therapeutic opportunity for nanoparticles and melatonin. ( Caballero-Román, A; Escribano-Ferrer, E; Figueroa, EG; Fornaguera, C; García-Celma, MJ; González-Candia, A; Herrera, EA, 2021) |
| "Improvements in encephalopathy and medical stabilization did not rapidly normalize rhythms." | 1.56 | Factors Disrupting Melatonin Secretion Rhythms During Critical Illness. ( Abbott, SM; Eed, J; Gendy, M; Liotta, EM; Lizza, BD; Maas, MB; Naidech, AM; Reid, KJ; Zee, PC, 2020) |
| "Melatonin (15 mg/kg) was administered by intraperitoneal injection at 1, 24, 48, and 72 h." | 1.35 | Long-term effects of melatonin after intracerebral hemorrhage in rats. ( Ayer, R; Hartman, RE; Jadhav, V; Lee, S; Lekic, T; Rojas, HA; Tang, J; Titova, E; Zhang, JH, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 4 (25.00) | 29.6817 |
| 2010's | 5 (31.25) | 24.3611 |
| 2020's | 5 (31.25) | 2.80 |
| Authors | Studies |
|---|---|
| Maas, MB | 1 |
| Lizza, BD | 1 |
| Abbott, SM | 1 |
| Liotta, EM | 1 |
| Gendy, M | 1 |
| Eed, J | 1 |
| Naidech, AM | 1 |
| Reid, KJ | 1 |
| Zee, PC | 1 |
| Liang, F | 2 |
| Wang, J | 1 |
| Zhu, X | 1 |
| Wang, Z | 2 |
| Zheng, J | 2 |
| Sun, Z | 2 |
| Xu, S | 2 |
| Zhang, J | 3 |
| Zhou, J | 1 |
| Shi, L | 2 |
| Zeng, L | 1 |
| Zhu, Y | 1 |
| Hu, X | 1 |
| Qin, H | 1 |
| Tang, J | 4 |
| Hu, Z | 1 |
| Chen, C | 1 |
| Figueroa, EG | 1 |
| González-Candia, A | 1 |
| Caballero-Román, A | 1 |
| Fornaguera, C | 1 |
| Escribano-Ferrer, E | 1 |
| García-Celma, MJ | 1 |
| Herrera, EA | 1 |
| Lorente, L | 1 |
| Martín, MM | 1 |
| Abreu-González, P | 1 |
| Ramos-Gómez, L | 1 |
| Argueso, M | 1 |
| Solé-Violán, J | 1 |
| Cáceres, JJ | 1 |
| Jiménez, A | 1 |
| Zhou, F | 1 |
| Dou, Y | 1 |
| Tian, X | 1 |
| Liu, C | 1 |
| Li, H | 1 |
| Shen, H | 1 |
| Chen, G | 1 |
| Lu, J | 1 |
| Fang, Y | 1 |
| Xu, W | 1 |
| Mei, S | 1 |
| Wu, H | 1 |
| Ueda, Y | 1 |
| Masuda, T | 1 |
| Ishida, A | 1 |
| Misumi, S | 1 |
| Shimizu, Y | 1 |
| Jung, CG | 1 |
| Hida, H | 1 |
| Wu, HJ | 1 |
| Wu, C | 1 |
| Niu, HJ | 1 |
| Wang, K | 1 |
| Mo, LJ | 1 |
| Shao, AW | 1 |
| Dixon, BJ | 1 |
| Zhang, JM | 1 |
| Yang, SX | 1 |
| Wang, YR | 1 |
| Hung, YC | 1 |
| Chen, TY | 1 |
| Lee, EJ | 1 |
| Chen, WL | 1 |
| Huang, SY | 1 |
| Lee, WT | 1 |
| Lee, MY | 1 |
| Chen, HY | 1 |
| Wu, TS | 1 |
| Rojas, H | 2 |
| Lekic, T | 3 |
| Chen, W | 2 |
| Jadhav, V | 2 |
| Titova, E | 2 |
| Martin, RD | 1 |
| Hartman, RE | 1 |
| Rojas, HA | 1 |
| Ayer, R | 2 |
| Lee, S | 1 |
| Zhang, JH | 2 |
| Li, ZQ | 1 |
| Liang, GB | 1 |
| Xue, YX | 1 |
| Liu, YH | 1 |
| Hartman, R | 1 |
| Manaenko, A | 1 |
| Yamada, N | 1 |
| Iwasa, H | 1 |
| Mori, S | 1 |
| Kurokawa, N | 1 |
| Fujimoto, K | 1 |
| Kawashima, K | 1 |
| Masuzawa, T | 1 |
| Pang, SF | 1 |
| Li, Y | 1 |
| Jiang, DH | 1 |
| Chang, B | 1 |
| Xie, BL | 1 |
3 reviews available for melatonin and Cerebral Hemorrhage
| Article | Year |
|---|---|
Efficacy of melatonin in animal models of intracerebral hemorrhage: a systematic review and meta-analysis.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cerebral Hemorrhage; Disease Models, Animal; Melato | 2021 |
Blood-brain barrier dysfunction in hemorrhagic transformation: a therapeutic opportunity for nanoparticles and melatonin.
Topics: Blood-Brain Barrier; Cerebral Hemorrhage; Humans; Melatonin; Nanoparticles; Neuroprotective Agents; | 2021 |
Neuroprotective Mechanisms of Melatonin in Hemorrhagic Stroke.
Topics: Animals; Cerebral Hemorrhage; Humans; Melatonin; Neuroprotective Agents; Signal Transduction; Stroke | 2017 |
13 other studies available for melatonin and Cerebral Hemorrhage
| Article | Year |
|---|---|
Factors Disrupting Melatonin Secretion Rhythms During Critical Illness.
Topics: Academic Medical Centers; Adult; Aged; Aged, 80 and over; Arousal; Brain Diseases; Cerebral Hemorrha | 2020 |
Melatonin Alleviates Neuronal Damage After Intracerebral Hemorrhage in Hyperglycemic Rats.
Topics: Animals; Cerebral Hemorrhage; Disease Models, Animal; Hyperglycemia; Injections, Intraperitoneal; Ma | 2020 |
Mortality prediction by serum melatonin levels of patients with spontaneous intracerebral hemorrhage.
Topics: Cerebral Hemorrhage; Glasgow Coma Scale; Humans; Melatonin; Prospective Studies | 2022 |
Melatonin Alleviates Intracerebral Hemorrhage-Induced Secondary Brain Injury in Rats via Suppressing Apoptosis, Inflammation, Oxidative Stress, DNA Damage, and Mitochondria Injury.
Topics: Animals; Annexin A5; Antioxidants; Apoptosis; Benzimidazoles; Brain Edema; Brain Injuries; Carbocyan | 2018 |
Melatonin Suppresses Microglial Necroptosis by Regulating Deubiquitinating Enzyme A20 After Intracerebral Hemorrhage.
Topics: Animals; Apoptosis; Brain Injuries; Cerebral Hemorrhage; Deubiquitinating Enzymes; Disease Models, A | 2019 |
Enhanced electrical responsiveness in the cerebral cortex with oral melatonin administration after a small hemorrhage near the internal capsule in rats.
Topics: Administration, Oral; Animals; Antioxidants; Cells, Cultured; Cerebral Cortex; Cerebral Hemorrhage; | 2014 |
Melatonin decreases matrix metalloproteinase-9 activation and expression and attenuates reperfusion-induced hemorrhage following transient focal cerebral ischemia in rats.
Topics: Animals; Blotting, Western; Brain; Brain Infarction; Cerebral Hemorrhage; Enzyme Activation; Gene Ex | 2008 |
The antioxidant effects of melatonin after intracerebral hemorrhage in rats.
Topics: Animals; Antioxidants; Basal Ganglia; Brain Edema; Cerebral Hemorrhage; Collagenases; Disease Models | 2008 |
Long-term effects of melatonin after intracerebral hemorrhage in rats.
Topics: Animals; Antioxidants; Behavior, Animal; Brain Infarction; Cerebral Hemorrhage; Collagenases; Corpus | 2008 |
Effects of combination treatment of dexamethasone and melatonin on brain injury in intracerebral hemorrhage model in rats.
Topics: Analysis of Variance; Animals; Apoptosis; bcl-2-Associated X Protein; Blood-Brain Barrier; Blotting, | 2009 |
Protective effect of melatonin upon neuropathology, striatal function, and memory ability after intracerebral hemorrhage in rats.
Topics: Animals; Antioxidants; Basal Ganglia Diseases; Cerebral Hemorrhage; Corpus Striatum; Disease Models, | 2010 |
Melatonin secretion in normal pressure hydrocephalus after cerebral aneurysm rupture--investigation before and after ventriculoperitoneal shunt.
Topics: Adolescent; Adult; Cerebral Hemorrhage; Cerebrospinal Fluid Shunts; Circadian Rhythm; Eye; Female; H | 1991 |
Acute cerebral hemorrhage changes the nocturnal surge of plasma melatonin in humans.
Topics: Acute Disease; Adolescent; Adult; Aged; Cerebral Hemorrhage; Circadian Rhythm; Female; Humans; Male; | 1990 |