Page last updated: 2024-10-19

melatonin and Cataract

melatonin has been researched along with Cataract in 20 studies

Cataract: Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"This study investigated the effect of oral melatonin as a premedication before cataract surgery on pain score, anxiety, surgical conditions, and intraocular pressure (IOP) during cataract surgery with phacoemulsification under topical anesthesia."9.69The Effect of Melatonin on Analgesia, Anxiety, and Intraocular Pressure (IOP) in Cataract Surgery Under Topical Anesthesia. ( Abdelbasset, WK; Golabi, P; Haki, BK; Komilzhonovich, IN; Mahmodi, H; Morwati, S; Motarjemizadeh, Q; Rahmani, N; Sane, S; Suksatan, W; Zaman, GS, 2023)
"Cataract surgery, which increases perception of light, may increase melatonin secretion."9.34Effects of Cataract Surgery on Melatonin Secretion in Adults 60 Years and Older: A Randomized Clinical Trial. ( Kurumatani, N; Miyata, K; Nishi, T; Obayashi, K; Ogata, N; Saeki, K; Ueda, T; Yoshikawa, T, 2020)
"We investigated the effects of melatonin on cataract formation in rats exposed to selenite."7.74Protective effects of melatonin on oxidative-antioxidative balance and cataract formation in rats. ( Aksoy, N; Erel, O; Kiliç, A; Selek, S, 2008)
"To evaluate effects of melatonin on sodium selenite-induced cataract formation."7.73Use of melatonin to prevent selenite-induced cataract formation in rat eyes. ( Aydin, B; Durmuş, M; Erdurmuş, M; Gürel, A; Karadağ, R; Yağci, R; Yiğitoğlu, R, 2006)
"We evaluated the inhibitory effect of melatonin, a recently discovered scavenger of free radicals, on cataract formation in the newborn rat."7.69Inhibitory effect of melatonin on cataract formation in newborn rats: evidence for an antioxidative role for melatonin. ( Abe, M; Hara, M; Orhii, PB; Poeggeler, B; Reiter, RJ, 1994)
"The purpose of this study was to examine the influence of exogenously administered melatonin on cataract formation and lipid peroxidation in newborn rats treated with buthionine sulfoximine (BSO), a drug which inhibits the rate-limiting enzyme in glutathione (GSH) synthesis, gamma-glutamylcysteine synthase, thereby depleting animals of their stores of the important intracellular antioxidant, GSH."7.69Cataractogenesis and lipid peroxidation in newborn rats treated with buthionine sulfoximine: preventive actions of melatonin. ( Duan, YP; Fujimori, O; Li, ZR; Oh, CS; Reiter, RJ, 1997)
"Cataracts are the main cause of reversible blindness worldwide."5.91Melatonin inhibits ferroptosis and delays age-related cataract by regulating SIRT6/p-Nrf2/GPX4 and SIRT6/NCOA4/FTH1 pathways. ( Ge, H; He, J; Liu, H; Liu, P; Luo, J; Mi, Y; Sun, L; Wei, C; Yu, X; Zhang, J, 2023)
"This study investigated the effect of oral melatonin as a premedication before cataract surgery on pain score, anxiety, surgical conditions, and intraocular pressure (IOP) during cataract surgery with phacoemulsification under topical anesthesia."5.69The Effect of Melatonin on Analgesia, Anxiety, and Intraocular Pressure (IOP) in Cataract Surgery Under Topical Anesthesia. ( Abdelbasset, WK; Golabi, P; Haki, BK; Komilzhonovich, IN; Mahmodi, H; Morwati, S; Motarjemizadeh, Q; Rahmani, N; Sane, S; Suksatan, W; Zaman, GS, 2023)
"Cataract surgery, which increases perception of light, may increase melatonin secretion."5.34Effects of Cataract Surgery on Melatonin Secretion in Adults 60 Years and Older: A Randomized Clinical Trial. ( Kurumatani, N; Miyata, K; Nishi, T; Obayashi, K; Ogata, N; Saeki, K; Ueda, T; Yoshikawa, T, 2020)
"We investigated the effects of melatonin on cataract formation in rats exposed to selenite."3.74Protective effects of melatonin on oxidative-antioxidative balance and cataract formation in rats. ( Aksoy, N; Erel, O; Kiliç, A; Selek, S, 2008)
"To evaluate effects of melatonin on sodium selenite-induced cataract formation."3.73Use of melatonin to prevent selenite-induced cataract formation in rat eyes. ( Aydin, B; Durmuş, M; Erdurmuş, M; Gürel, A; Karadağ, R; Yağci, R; Yiğitoğlu, R, 2006)
"To investigate the defensive effect of melatonin against oxidative stresses in ultraviolet-B (UVB) radiation induced cataract development."3.70Effect of melatonin against oxidative stress in ultraviolet-B exposed rat lens. ( Bardak, Y; Delibaş, N; Durmuş, M; Ozertürk, Y; Ozgüner, F, 2000)
"We evaluated the inhibitory effect of melatonin, a recently discovered scavenger of free radicals, on cataract formation in the newborn rat."3.69Inhibitory effect of melatonin on cataract formation in newborn rats: evidence for an antioxidative role for melatonin. ( Abe, M; Hara, M; Orhii, PB; Poeggeler, B; Reiter, RJ, 1994)
"The purpose of this study was to examine the influence of exogenously administered melatonin on cataract formation and lipid peroxidation in newborn rats treated with buthionine sulfoximine (BSO), a drug which inhibits the rate-limiting enzyme in glutathione (GSH) synthesis, gamma-glutamylcysteine synthase, thereby depleting animals of their stores of the important intracellular antioxidant, GSH."3.69Cataractogenesis and lipid peroxidation in newborn rats treated with buthionine sulfoximine: preventive actions of melatonin. ( Duan, YP; Fujimori, O; Li, ZR; Oh, CS; Reiter, RJ, 1997)
"Cataracts are the main cause of reversible blindness worldwide."1.91Melatonin inhibits ferroptosis and delays age-related cataract by regulating SIRT6/p-Nrf2/GPX4 and SIRT6/NCOA4/FTH1 pathways. ( Ge, H; He, J; Liu, H; Liu, P; Luo, J; Mi, Y; Sun, L; Wei, C; Yu, X; Zhang, J, 2023)
"When melatonin was injected after radiation, SOD and GSH-Px enzyme activities increased significantly (P<0."1.31The effect of melatonin on eye lens of rats exposed to ultraviolet radiation. ( Anwar, MM; Moustafa, MA, 2001)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (10.00)18.2507
2000's7 (35.00)29.6817
2010's6 (30.00)24.3611
2020's5 (25.00)2.80

Authors

AuthorsStudies
Lledó, VE2
Alkozi, HA2
Sánchez-Naves, J2
Fernandez-Torres, MA2
Guzman-Aranguez, A2
Sane, S1
Motarjemizadeh, Q1
Komilzhonovich, IN1
Abdelbasset, WK1
Zaman, GS1
Suksatan, W1
Morwati, S1
Haki, BK1
Rahmani, N1
Golabi, P1
Mahmodi, H1
Mi, Y3
Wei, C3
Sun, L3
Liu, H3
Zhang, J3
Luo, J3
Yu, X3
He, J3
Ge, H3
Liu, P3
Nishi, T1
Saeki, K1
Miyata, K1
Yoshikawa, T1
Ueda, T1
Kurumatani, N1
Obayashi, K1
Ogata, N1
Akdogan, M1
Budak, YU1
Huysal, K1
Wang, MS1
Liu, MY1
Dong, XR1
Wang, W1
Shenshen, Y1
Minshu, W1
Qing, Y1
Yang, L1
Suodi, Z1
Wei, W1
Mahlberg, R1
Kiliç, A1
Selek, S1
Erel, O1
Aksoy, N1
Craiu, AM1
Tanaka, M1
Hosoe, K1
Hamada, T1
Morita, T1
Karslioglu, I1
Ertekin, MV1
Taysi, S1
Koçer, I1
Sezen, O1
Gepdiremen, A1
Koç, M1
Bakan, N1
Siu, AW1
Maldonado, M1
Sanchez-Hidalgo, M1
Tan, DX2
Reiter, RJ4
Yağci, R1
Aydin, B1
Erdurmuş, M1
Karadağ, R1
Gürel, A1
Durmuş, M2
Yiğitoğlu, R1
Manchester, LC1
Pilar Terron, M1
Flores, LJ1
Koppisepi, S1
Abe, M1
Orhii, PB1
Hara, M1
Poeggeler, B1
Li, ZR1
Fujimori, O1
Oh, CS1
Duan, YP1
Bardak, Y1
Ozertürk, Y1
Ozgüner, F1
Delibaş, N1
Anwar, MM1
Moustafa, MA1

Reviews

4 reviews available for melatonin and Cataract

ArticleYear
[Impact of age-related cataract on regulation of circadian rhythm in elderly].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 2016, Apr-11, Volume: 52, Issue:4

    Topics: Age Factors; Aged; Cataract; Circadian Rhythm; Humans; Melatonin; Photoreceptor Cells; Pineal Gland;

2016
[About entropy in ophthalmology].
    Oftalmologia (Bucharest, Romania : 1990), 2010, Volume: 54, Issue:2

    Topics: Biological Evolution; Cataract; Entropy; Eye Diseases; Humans; Kinetics; Lens, Crystalline; Melatoni

2010
Protective effects of melatonin in experimental free radical-related ocular diseases.
    Journal of pineal research, 2006, Volume: 40, Issue:2

    Topics: Antioxidants; Cataract; Eye Diseases; Glaucoma; Humans; Keratitis; Melatonin; Ocular Physiological P

2006
Medical implications of melatonin: receptor-mediated and receptor-independent actions.
    Advances in medical sciences, 2007, Volume: 52

    Topics: Animals; Antioxidants; Cataract; Free Radicals; Humans; Hyperoxia; Hyperthyroidism; Melatonin; Model

2007

Trials

2 trials available for melatonin and Cataract

ArticleYear
The Effect of Melatonin on Analgesia, Anxiety, and Intraocular Pressure (IOP) in Cataract Surgery Under Topical Anesthesia.
    Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses, 2023, Volume: 38, Issue:2

    Topics: Analgesia; Anesthesia, Local; Anxiety; Cataract; Double-Blind Method; Humans; Intraocular Pressure;

2023
Effects of Cataract Surgery on Melatonin Secretion in Adults 60 Years and Older: A Randomized Clinical Trial.
    JAMA ophthalmology, 2020, 04-01, Volume: 138, Issue:4

    Topics: Aged; Aged, 80 and over; Cataract; Creatinine; Double-Blind Method; Enzyme-Linked Immunosorbent Assa

2020

Other Studies

14 other studies available for melatonin and Cataract

ArticleYear
Melatonin counteracts oxidative damage in lens by regulation of Nrf2 and NLRP3 inflammasome activity.
    Experimental eye research, 2022, Volume: 215

    Topics: Cataract; Humans; Hydrogen Peroxide; Inflammasomes; Melatonin; NF-E2-Related Factor 2; NLR Family, P

2022
Melatonin inhibits ferroptosis and delays age-related cataract by regulating SIRT6/p-Nrf2/GPX4 and SIRT6/NCOA4/FTH1 pathways.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Cataract; Ferritins; Ferroptosis; HEK293 Cells; Humans; Melatonin; NF-E2-Related Factor 2;

2023
Melatonin inhibits ferroptosis and delays age-related cataract by regulating SIRT6/p-Nrf2/GPX4 and SIRT6/NCOA4/FTH1 pathways.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Cataract; Ferritins; Ferroptosis; HEK293 Cells; Humans; Melatonin; NF-E2-Related Factor 2;

2023
Melatonin inhibits ferroptosis and delays age-related cataract by regulating SIRT6/p-Nrf2/GPX4 and SIRT6/NCOA4/FTH1 pathways.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Cataract; Ferritins; Ferroptosis; HEK293 Cells; Humans; Melatonin; NF-E2-Related Factor 2;

2023
Melatonin inhibits ferroptosis and delays age-related cataract by regulating SIRT6/p-Nrf2/GPX4 and SIRT6/NCOA4/FTH1 pathways.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Cataract; Ferritins; Ferroptosis; HEK293 Cells; Humans; Melatonin; NF-E2-Related Factor 2;

2023
Modulation of aqueous humor melatonin levels by yellow-filter and its protective effect on lens.
    Journal of photochemistry and photobiology. B, Biology, 2021, Volume: 221

    Topics: Aged; Animals; Aqueous Humor; Cataract; Cell Survival; Diabetes Mellitus, Experimental; Epithelial C

2021
Urinary 6-sulphatoxymelatonin levels in patients with senile cataracts.
    BMC ophthalmology, 2013, Sep-22, Volume: 13

    Topics: Aged; Aging; Antioxidants; Case-Control Studies; Cataract; Enzyme-Linked Immunosorbent Assay; Female

2013
The effect of cataract surgery on salivary melatonin and sleep quality in aging people.
    Chronobiology international, 2016, Volume: 33, Issue:8

    Topics: Aged; Aged, 80 and over; Cataract; Cataract Extraction; Female; Humans; Light; Male; Melatonin; Sali

2016
[Sleep Disturbances in the Elderly].
    Deutsche medizinische Wochenschrift (1946), 2016, Volume: 141, Issue:16

    Topics: Aged; Aged, 80 and over; Aging; Cataract; Circadian Rhythm; Humans; Melatonin; Sleep Apnea Syndromes

2016
Protective effects of melatonin on oxidative-antioxidative balance and cataract formation in rats.
    Annals of ophthalmology (Skokie, Ill.), 2008,Spring, Volume: 40, Issue:1

    Topics: Animals; Animals, Newborn; Antioxidants; Aryldialkylphosphatase; Carboxylic Ester Hydrolases; Catala

2008
Change in sleep state of the elderly before and after cataract surgery.
    Journal of physiological anthropology, 2010, Volume: 29, Issue:6

    Topics: Aged; Aged, 80 and over; Cataract; Cataract Extraction; Circadian Rhythm; Female; Humans; Male; Mela

2010
Radioprotective effects of melatonin on radiation-induced cataract.
    Journal of radiation research, 2005, Volume: 46, Issue:2

    Topics: Animals; Antioxidants; Cataract; Disease Models, Animal; Female; Free Radical Scavengers; Heavy Ions

2005
Use of melatonin to prevent selenite-induced cataract formation in rat eyes.
    Current eye research, 2006, Volume: 31, Issue:10

    Topics: Animals; Animals, Newborn; Antioxidants; Catalase; Cataract; Disease Models, Animal; Lens, Crystalli

2006
Inhibitory effect of melatonin on cataract formation in newborn rats: evidence for an antioxidative role for melatonin.
    Journal of pineal research, 1994, Volume: 17, Issue:2

    Topics: Animals; Animals, Newborn; Antioxidants; Brain; Buthionine Sulfoximine; Cataract; Free Radical Scave

1994
Cataractogenesis and lipid peroxidation in newborn rats treated with buthionine sulfoximine: preventive actions of melatonin.
    Journal of pineal research, 1997, Volume: 22, Issue:3

    Topics: Animals; Animals, Newborn; Antioxidants; Brain; Buthionine Sulfoximine; Cataract; Enzyme Inhibitors;

1997
Effect of melatonin against oxidative stress in ultraviolet-B exposed rat lens.
    Current eye research, 2000, Volume: 20, Issue:3

    Topics: Animals; Antioxidants; Catalase; Cataract; Female; Glutathione; Glutathione Peroxidase; Lens, Crysta

2000
The effect of melatonin on eye lens of rats exposed to ultraviolet radiation.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2001, Volume: 129, Issue:1

    Topics: Animals; Antioxidants; Biological Assay; Calcium; Cataract; Glutathione Peroxidase; L-Lactate Dehydr

2001