Page last updated: 2024-10-19

melatonin and Cardiac Failure

melatonin has been researched along with Cardiac Failure in 26 studies

Research Excerpts

ExcerptRelevanceReference
"Melatonin, the major secretion of the pineal gland, has beneficial effects on the cardiovascular system and might advantage heart failure with reduced ejection fraction (HFrEF) by attenuating the effects of the renin-angiotensin-aldosterone and sympathetic system on the heart besides its antioxidant and anti-inflammatory effects."9.51Melatonin supplementation improves N-terminal pro-B-type natriuretic peptide levels and quality of life in patients with heart failure with reduced ejection fraction: Results from MeHR trial, a randomized clinical trial. ( Azizi, E; Garakyaraghi, M; Heshmat-Ghahdarijani, K; Hoseini, SG; Khosrawi, S; Mansourian, M; Roohafza, H; Sadeghi, M; Shafie, D, 2022)
"The current study (clinical trial registered number: CHWX-904-201511) suggests that acute melatonin treatment can reduce the incidence of delirium for elderly acute heart failure."9.51Effects of Melatonin for Delirium in Elderly Acute Heart Failure Patients: A Randomized, Single-Center, Double-Blind, and Placebo-Controlled Trial. ( Gu, L; Liu, X; Wan, R; Ye, T; Yin, B; Zong, G, 2022)
"This study aimed to investigate the effect of melatonin supplementation on endothelial function in patients with heart failure with reduced ejection fraction (HFrEF)."9.41Effect of melatonin supplementation on endothelial function in heart failure with reduced ejection fraction: A randomized, double-blinded clinical trial. ( Azizi, E; Garakyaraghi, M; Gheisari, Y; Heshmat-Ghahdarijani, K; Hoseini, SG; Khosrawi, S; Mansourian, M; Roohafza, H; Sadeghi, M; Shafie, D, 2021)
"Current studies indicate that melatonin can counteract renin-angiotensin-aldosterone system and sympathetic over activity in heart failure (HF) and might have a protective and repairing effect on cardiovascular injuries, skeletal muscle weakness, and metabolic abnormalities, which are common pathological processes in patients with HF."9.34Effect of melatonin on heart failure: design for a double-blinded randomized clinical trial. ( Gheisari, Y; Heshmat-Ghahdarijani, K; Hoseini, SG; Khosrawi, S; Mansoorian, M; Roohafza, H; Sadeghi, M, 2020)
"Melatonin has been shown to inhibit myocardial infarction-induced apoptosis, its function in heart failure with preserved ejection fraction (HFpEF) has not been investigated."7.88Melatonin improves cardiac function in a mouse model of heart failure with preserved ejection fraction. ( Dong, JZ; Gao, L; Guo, S; Li, L; Li, LN; Liang, C; Liu, Y; Liu, YZ; Tu, S; Wang, D; Yang, HB; Zhao, XY, 2018)
"To assess the significance of melatonin, NT-proBNP and morphological markers of myocardial remodeling for predicting the risk of complications after coronary artery bypass grafting (CABG) in patients with ischemic heart disease and chronic heart failure (CHF)."7.85[Prognostic Value of Melatonin Level, Structural and Functional Changes of the Myocardium in the Development of Complications in Patients With Heart Failure who Underwent Coronary Artery Bypass Grafting: the Possibilities of Pharmacological Cardioprotecti ( Avchenko, GM; Erkhov, AY; Liskova, YV; Popov, AB; Rozhkov, VO; Salikova, SP; Selivanov, SA; Stadnikov, AA; Tverdokhlib, NB, 2017)
" This study investigated whether melatonin prevents LV remodeling and improves survival in isoproterenol-induced heart failure."7.80Melatonin reduces cardiac remodeling and improves survival in rats with isoproterenol-induced heart failure. ( Adamcova, M; Bednarova, KR; Celec, P; Gajdosechova, L; Hrenak, J; Kamodyova, N; Krajcirovicova, K; Simko, F; Zorad, S, 2014)
"The aim of the study was to examine the reorganization of extracellular matrix left ventricular myocardium (LVM) rats (n = 38) with experimental heart failure (EHF) as affected by perindopril and melatonin administration."7.80[Extracellular matrix remodeling myocardium of the left ventricle rats with experimental heart failure after perindopril and melatonin administration]. ( Liskova, IuV; Salikova, SP; Stadnikov, AA, 2014)
"Assessment of the alteration in diurnal and nocturnal melatonin serum levels in patients with chronic heart failure."7.79Alteration in diurnal and nocturnal melatonin serum level in patients with chronic heart failure. ( Dzida, G; Hałabiś, M; Kadas, T; Kamieński, P; Kiciński, P; Kimak, E; Lachowska-Kotowska, P; Prystupa, A, 2013)
"The aim of the study was to examine the reorganization of left ventricular myocardium (LVM) in ovariectomized rats with experimental heart failure (EHF) as affected by melatonin administration."7.79[Structural reorganization of the myocardium in ovariectomized rats with experimental heart failure after melatonin administration]. ( Liskova, IuV; Salikova, SP; Stadnikov, AA, 2013)
"To assess urinary 6-sulfatoxymelatonin excretion in patients admitted to the hospital because of congestive heart failure (CHF)."7.72Low urinary 6-sulfatoxymelatonin levels in patients with severe congestive heart failure. ( Albornoz, LE; Cardinali, DP; Dini, A; Elizari, MV; Girotti, L; Ianovsky, O; Lago, M; Pérez Lloret, S, 2003)
"Melatonin plays a crucial role in major pathological processes associated with heart failure including ischemic injury, oxidative stress, apoptosis, and cardiac remodeling."6.58Melatonin in Heart Failure: A Promising Therapeutic Strategy? ( Maarman, GJ; Nduhirabandi, F, 2018)
"Melatonin treatment for 8 weeks markedly attenuated cardiac hypertrophy and restored impaired cardiac function, as indicated by a decreased HW/BW ratio, reduced cell cross-sectional area and fibrosis, downregulated the mRNA levels of ANP, BNP, and β-MHC and ameliorated adverse effects on the LVEF and LVFS."5.56Melatonin ameliorates pressure overload-induced cardiac hypertrophy by attenuating Atg5-dependent autophagy and activating the Akt/mTOR pathway. ( Ding, P; Fan, ZG; Gao, EH; Kong, LH; Liu, Y; Xu, CN; Yang, J; Yang, LF, 2020)
"Melatonin, the major secretion of the pineal gland, has beneficial effects on the cardiovascular system and might advantage heart failure with reduced ejection fraction (HFrEF) by attenuating the effects of the renin-angiotensin-aldosterone and sympathetic system on the heart besides its antioxidant and anti-inflammatory effects."5.51Melatonin supplementation improves N-terminal pro-B-type natriuretic peptide levels and quality of life in patients with heart failure with reduced ejection fraction: Results from MeHR trial, a randomized clinical trial. ( Azizi, E; Garakyaraghi, M; Heshmat-Ghahdarijani, K; Hoseini, SG; Khosrawi, S; Mansourian, M; Roohafza, H; Sadeghi, M; Shafie, D, 2022)
"The current study (clinical trial registered number: CHWX-904-201511) suggests that acute melatonin treatment can reduce the incidence of delirium for elderly acute heart failure."5.51Effects of Melatonin for Delirium in Elderly Acute Heart Failure Patients: A Randomized, Single-Center, Double-Blind, and Placebo-Controlled Trial. ( Gu, L; Liu, X; Wan, R; Ye, T; Yin, B; Zong, G, 2022)
" A histological analysis revealed that chronic intake of MEL diminished the age-dependent changes in the structure of muscle fibers of the left ventricle, muscle fiber swelling, and injury zones characteristic of acute cardiac failure caused by ISO."5.48Effect of Melatonin on Rat Heart Mitochondria in Acute Heart Failure in Aged Rats. ( Akatov, V; Baburina, Y; Fadeeva, I; Krestinina, O; Kruglov, A; Odinokova, I; Sotnikova, L; Zvyagina, A, 2018)
"Melatonin is a secretory product of the pineal gland with highly beneficial effects from any tissues including the heart."5.43Melatonin is associated with reverse remodeling after cardiac resynchronization therapy in patients with heart failure and ventricular dyssynchrony. ( Abreu-Gonzalez, P; Dominguez-Rodriguez, A; Galasso, G; Piccolo, R; Reiter, RJ, 2016)
"This study aimed to investigate the effect of melatonin supplementation on endothelial function in patients with heart failure with reduced ejection fraction (HFrEF)."5.41Effect of melatonin supplementation on endothelial function in heart failure with reduced ejection fraction: A randomized, double-blinded clinical trial. ( Azizi, E; Garakyaraghi, M; Gheisari, Y; Heshmat-Ghahdarijani, K; Hoseini, SG; Khosrawi, S; Mansourian, M; Roohafza, H; Sadeghi, M; Shafie, D, 2021)
"Current studies indicate that melatonin can counteract renin-angiotensin-aldosterone system and sympathetic over activity in heart failure (HF) and might have a protective and repairing effect on cardiovascular injuries, skeletal muscle weakness, and metabolic abnormalities, which are common pathological processes in patients with HF."5.34Effect of melatonin on heart failure: design for a double-blinded randomized clinical trial. ( Gheisari, Y; Heshmat-Ghahdarijani, K; Hoseini, SG; Khosrawi, S; Mansoorian, M; Roohafza, H; Sadeghi, M, 2020)
"Melatonin has been shown to inhibit myocardial infarction-induced apoptosis, its function in heart failure with preserved ejection fraction (HFpEF) has not been investigated."3.88Melatonin improves cardiac function in a mouse model of heart failure with preserved ejection fraction. ( Dong, JZ; Gao, L; Guo, S; Li, L; Li, LN; Liang, C; Liu, Y; Liu, YZ; Tu, S; Wang, D; Yang, HB; Zhao, XY, 2018)
"To assess the significance of melatonin, NT-proBNP and morphological markers of myocardial remodeling for predicting the risk of complications after coronary artery bypass grafting (CABG) in patients with ischemic heart disease and chronic heart failure (CHF)."3.85[Prognostic Value of Melatonin Level, Structural and Functional Changes of the Myocardium in the Development of Complications in Patients With Heart Failure who Underwent Coronary Artery Bypass Grafting: the Possibilities of Pharmacological Cardioprotecti ( Avchenko, GM; Erkhov, AY; Liskova, YV; Popov, AB; Rozhkov, VO; Salikova, SP; Selivanov, SA; Stadnikov, AA; Tverdokhlib, NB, 2017)
" This study investigated whether melatonin prevents LV remodeling and improves survival in isoproterenol-induced heart failure."3.80Melatonin reduces cardiac remodeling and improves survival in rats with isoproterenol-induced heart failure. ( Adamcova, M; Bednarova, KR; Celec, P; Gajdosechova, L; Hrenak, J; Kamodyova, N; Krajcirovicova, K; Simko, F; Zorad, S, 2014)
"The aim of the study was to examine the reorganization of extracellular matrix left ventricular myocardium (LVM) rats (n = 38) with experimental heart failure (EHF) as affected by perindopril and melatonin administration."3.80[Extracellular matrix remodeling myocardium of the left ventricle rats with experimental heart failure after perindopril and melatonin administration]. ( Liskova, IuV; Salikova, SP; Stadnikov, AA, 2014)
"Assessment of the alteration in diurnal and nocturnal melatonin serum levels in patients with chronic heart failure."3.79Alteration in diurnal and nocturnal melatonin serum level in patients with chronic heart failure. ( Dzida, G; Hałabiś, M; Kadas, T; Kamieński, P; Kiciński, P; Kimak, E; Lachowska-Kotowska, P; Prystupa, A, 2013)
"The aim of the study was to examine the reorganization of left ventricular myocardium (LVM) in ovariectomized rats with experimental heart failure (EHF) as affected by melatonin administration."3.79[Structural reorganization of the myocardium in ovariectomized rats with experimental heart failure after melatonin administration]. ( Liskova, IuV; Salikova, SP; Stadnikov, AA, 2013)
"To assess urinary 6-sulfatoxymelatonin excretion in patients admitted to the hospital because of congestive heart failure (CHF)."3.72Low urinary 6-sulfatoxymelatonin levels in patients with severe congestive heart failure. ( Albornoz, LE; Cardinali, DP; Dini, A; Elizari, MV; Girotti, L; Ianovsky, O; Lago, M; Pérez Lloret, S, 2003)
"Melatonin plays a crucial role in major pathological processes associated with heart failure including ischemic injury, oxidative stress, apoptosis, and cardiac remodeling."2.58Melatonin in Heart Failure: A Promising Therapeutic Strategy? ( Maarman, GJ; Nduhirabandi, F, 2018)
"Melatonin treatment for 8 weeks markedly attenuated cardiac hypertrophy and restored impaired cardiac function, as indicated by a decreased HW/BW ratio, reduced cell cross-sectional area and fibrosis, downregulated the mRNA levels of ANP, BNP, and β-MHC and ameliorated adverse effects on the LVEF and LVFS."1.56Melatonin ameliorates pressure overload-induced cardiac hypertrophy by attenuating Atg5-dependent autophagy and activating the Akt/mTOR pathway. ( Ding, P; Fan, ZG; Gao, EH; Kong, LH; Liu, Y; Xu, CN; Yang, J; Yang, LF, 2020)
" A histological analysis revealed that chronic intake of MEL diminished the age-dependent changes in the structure of muscle fibers of the left ventricle, muscle fiber swelling, and injury zones characteristic of acute cardiac failure caused by ISO."1.48Effect of Melatonin on Rat Heart Mitochondria in Acute Heart Failure in Aged Rats. ( Akatov, V; Baburina, Y; Fadeeva, I; Krestinina, O; Kruglov, A; Odinokova, I; Sotnikova, L; Zvyagina, A, 2018)
"Melatonin is a secretory product of the pineal gland with highly beneficial effects from any tissues including the heart."1.43Melatonin is associated with reverse remodeling after cardiac resynchronization therapy in patients with heart failure and ventricular dyssynchrony. ( Abreu-Gonzalez, P; Dominguez-Rodriguez, A; Galasso, G; Piccolo, R; Reiter, RJ, 2016)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.85)18.7374
1990's2 (7.69)18.2507
2000's4 (15.38)29.6817
2010's11 (42.31)24.3611
2020's8 (30.77)2.80

Authors

AuthorsStudies
Hoseini, SG3
Heshmat-Ghahdarijani, K3
Khosrawi, S3
Garakyaraghi, M2
Shafie, D2
Mansourian, M2
Roohafza, H3
Azizi, E2
Sadeghi, M3
Yin, B1
Ye, T1
Liu, X1
Wan, R1
Gu, L1
Zong, G1
Crnko, S1
Printezi, MI1
Zwetsloot, PM1
Leiteris, L1
Lumley, AI1
Zhang, L1
Ernens, I1
Jansen, TPJ1
Homsma, L1
Feyen, D1
van Faassen, M1
du Pré, BC1
Gaillard, CAJM1
Kemperman, H1
Oerlemans, MIFJ1
Doevendans, PAFM1
May, AM1
Zuithoff, NPA1
Sluijter, JPG1
Devaux, Y1
van Laake, LW1
Thonusin, C1
Nawara, W1
Arinno, A1
Khuanjing, T1
Prathumsup, N1
Ongnok, B1
Chattipakorn, SC1
Chattipakorn, N1
Davis, H1
Attwell, D1
Xu, CN1
Kong, LH1
Ding, P1
Liu, Y2
Fan, ZG1
Gao, EH1
Yang, J1
Yang, LF1
Gheisari, Y2
Mansoorian, M1
Salikova, SP3
Liskova, YV1
Stadnikov, AA3
Selivanov, SA1
Tverdokhlib, NB1
Rozhkov, VO1
Avchenko, GM1
Erkhov, AY1
Popov, AB1
Odinokova, I1
Baburina, Y1
Kruglov, A1
Fadeeva, I1
Zvyagina, A1
Sotnikova, L1
Akatov, V1
Krestinina, O1
Li, LN1
Guo, S1
Zhao, XY1
Liu, YZ1
Liang, C1
Tu, S1
Wang, D1
Li, L1
Dong, JZ1
Gao, L1
Yang, HB1
Nduhirabandi, F1
Maarman, GJ1
Şehirli, AÖ1
Koyun, D1
Tetik, Ş1
Özsavcı, D1
Yiğiner, Ö1
Çetinel, Ş1
Tok, OE1
Kaya, Z1
Akkiprik, M1
Kılıç, E1
Şener, G1
Dzida, G1
Prystupa, A1
Lachowska-Kotowska, P1
Kadas, T1
Kamieński, P1
Kimak, E1
Hałabiś, M1
Kiciński, P1
Liskova, IuV2
Dominguez-Rodriguez, A2
Abreu-Gonzalez, P2
Reiter, RJ2
Simko, F1
Bednarova, KR1
Krajcirovicova, K1
Hrenak, J1
Celec, P1
Kamodyova, N1
Gajdosechova, L1
Zorad, S1
Adamcova, M1
Piccolo, R1
Galasso, G1
Chen, LG1
Qu, Y1
Xiao, J1
Guo, HL1
Wan, CM1
Wang, ZR1
Girotti, L1
Lago, M1
Ianovsky, O1
Elizari, MV1
Dini, A1
Pérez Lloret, S1
Albornoz, LE1
Cardinali, DP1
Lisitsa, GV1
Zaslavskaia, RM1
Kalinina, EV1
Scheer, FA1
Stone, PH1
Shea, SA1
Natelson, BH1
Ottenweller, JE1
Tapp, WN1
Heung, S1
Beldowicz, D1
Morishima, I1
Matsui, H1
Mukawa, H1
Hayashi, K1
Toki, Y1
Okumura, K1
Ito, T1
Hayakawa, T1
Malaia, LT1
Rachinskiĭ, ID1
Shushliapin, OI1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Association Between Plasma Melatonin and No-reflow[NCT03306303]1,700 participants (Actual)Observational2014-01-01Completed
A Triple Blinded Randomized Controlled Trial of Oral Melatonin in Elevated Blood Pressure Individual (MRCTEBP)[NCT03764020]Phase 3320 participants (Anticipated)Interventional2019-06-01Not yet recruiting
Restoration of Sleep in Heart Failure Patients[NCT00869869]Phase 20 participants (Actual)Interventional2009-03-31Withdrawn (stopped due to No subjects were enrolled in this study. Funding ran out.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for melatonin and Cardiac Failure

ArticleYear
Melatonin in Heart Failure: A Promising Therapeutic Strategy?
    Molecules (Basel, Switzerland), 2018, Jul-22, Volume: 23, Issue:7

    Topics: Animals; Fibrosis; Heart Failure; Humans; Hypertension; Melatonin

2018

Trials

5 trials available for melatonin and Cardiac Failure

ArticleYear
Melatonin supplementation improves N-terminal pro-B-type natriuretic peptide levels and quality of life in patients with heart failure with reduced ejection fraction: Results from MeHR trial, a randomized clinical trial.
    Clinical cardiology, 2022, Volume: 45, Issue:4

    Topics: Dietary Supplements; Heart Failure; Humans; Melatonin; Natriuretic Peptide, Brain; Peptide Fragments

2022
Effects of Melatonin for Delirium in Elderly Acute Heart Failure Patients: A Randomized, Single-Center, Double-Blind, and Placebo-Controlled Trial.
    The heart surgery forum, 2022, Jan-17, Volume: 25, Issue:1

    Topics: Aged; Delirium; Double-Blind Method; Heart Failure; Humans; Length of Stay; Melatonin; Treatment Out

2022
Effect of melatonin on heart failure: design for a double-blinded randomized clinical trial.
    ESC heart failure, 2020, Volume: 7, Issue:5

    Topics: Double-Blind Method; Heart Failure; Hospitalization; Humans; Melatonin; Quality of Life

2020
Effect of melatonin supplementation on endothelial function in heart failure with reduced ejection fraction: A randomized, double-blinded clinical trial.
    Clinical cardiology, 2021, Volume: 44, Issue:9

    Topics: Dietary Supplements; Double-Blind Method; Female; Heart Failure; Humans; Male; Melatonin; Middle Age

2021
[Effectiveness of metabolic preparations in complex treatment of elderly patients with postinfarction cardiosclerosis and circulatory insufficiency].
    Klinicheskaia meditsina, 2005, Volume: 83, Issue:3

    Topics: Administration, Oral; Administration, Sublingual; Adrenergic beta-Antagonists; Aged; Amino Acids; An

2005

Other Studies

20 other studies available for melatonin and Cardiac Failure

ArticleYear
The circadian clock remains intact, but with dampened hormonal output in heart failure.
    EBioMedicine, 2023, Volume: 91

    Topics: Animals; Circadian Clocks; Circadian Rhythm; Female; Heart Failure; Humans; Hydrocortisone; Male; Me

2023
Effects of melatonin on cardiac metabolic reprogramming in doxorubicin-induced heart failure rats: A metabolomics study for potential therapeutic targets.
    Journal of pineal research, 2023, Volume: 75, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Doxorubicin; Heart; Heart Failure; Ketones; Male; Melatonin; M

2023
Heart failure causes sleepless nights.
    Science (New York, N.Y.), 2023, 07-21, Volume: 381, Issue:6655

    Topics: Heart Failure; Humans; Melatonin; Pineal Gland; Sleep Disorders, Circadian Rhythm

2023
Melatonin ameliorates pressure overload-induced cardiac hypertrophy by attenuating Atg5-dependent autophagy and activating the Akt/mTOR pathway.
    Biochimica et biophysica acta. Molecular basis of disease, 2020, 10-01, Volume: 1866, Issue:10

    Topics: Animals; Apoptosis; Autophagy; Autophagy-Related Protein 5; Cardiomegaly; Disease Models, Animal; Fi

2020
[Prognostic Value of Melatonin Level, Structural and Functional Changes of the Myocardium in the Development of Complications in Patients With Heart Failure who Underwent Coronary Artery Bypass Grafting: the Possibilities of Pharmacological Cardioprotecti
    Kardiologiia, 2017, Volume: 57, Issue:10

    Topics: Coronary Artery Bypass; Heart Failure; Humans; Melatonin; Myocardium; Postoperative Complications; P

2017
Effect of Melatonin on Rat Heart Mitochondria in Acute Heart Failure in Aged Rats.
    International journal of molecular sciences, 2018, 05-23, Volume: 19, Issue:6

    Topics: 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase; Aging; Animals; Calcium; Cell Respiration; Cryoultrami

2018
Melatonin improves cardiac function in a mouse model of heart failure with preserved ejection fraction.
    Redox biology, 2018, Volume: 18

    Topics: Adipokines; Animals; Antioxidants; Apoptosis; Diet, High-Fat; Disease Models, Animal; Heart Failure;

2018
Melatonin protects against ischemic heart failure in rats.
    Journal of pineal research, 2013, Volume: 55, Issue:2

    Topics: Animals; Antioxidants; Disease Models, Animal; Drug Evaluation, Preclinical; Heart; Heart Failure; M

2013
Alteration in diurnal and nocturnal melatonin serum level in patients with chronic heart failure.
    Annals of agricultural and environmental medicine : AAEM, 2013, Volume: 20, Issue:4

    Topics: Aged; Aged, 80 and over; C-Reactive Protein; Circadian Rhythm; Heart Failure; Humans; Melatonin; Mid

2013
[Structural reorganization of the myocardium in ovariectomized rats with experimental heart failure after melatonin administration].
    Morfologiia (Saint Petersburg, Russia), 2013, Volume: 144, Issue:5

    Topics: Animals; Apoptosis; Female; Heart; Heart Failure; Heart Ventricles; Humans; Melatonin; Myocardium; M

2013
The potential usefulness of serum melatonin level to predict heart failure in patients with hypertensive cardiomyopathy.
    International journal of cardiology, 2014, Jun-15, Volume: 174, Issue:2

    Topics: Cardiomyopathies; Female; Heart Failure; Humans; Hypertension; Male; Melatonin; Middle Aged; Predict

2014
Melatonin reduces cardiac remodeling and improves survival in rats with isoproterenol-induced heart failure.
    Journal of pineal research, 2014, Volume: 57, Issue:2

    Topics: Animals; Cardiomegaly; Heart Failure; Isoproterenol; Male; Melatonin; Rats; Rats, Wistar

2014
[Extracellular matrix remodeling myocardium of the left ventricle rats with experimental heart failure after perindopril and melatonin administration].
    Kardiologiia, 2014, Volume: 54, Issue:9

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Disease Models, Animal; Extracellul

2014
Melatonin is associated with reverse remodeling after cardiac resynchronization therapy in patients with heart failure and ventricular dyssynchrony.
    International journal of cardiology, 2016, Oct-15, Volume: 221

    Topics: Aged; Cardiac Resynchronization Therapy; Echocardiography; Female; Follow-Up Studies; Heart Atria; H

2016
[Encapsulation of atrial natriuretic peptide (ANP) cDNA transfection cells and ANP circadian expression].
    Hang tian yi xue yu yi xue gong cheng = Space medicine & medical engineering, 2003, Volume: 16, Issue:3

    Topics: Animals; Atrial Natriuretic Factor; Caproates; CHO Cells; Circadian Rhythm; Cricetinae; Drug Deliver

2003
Low urinary 6-sulfatoxymelatonin levels in patients with severe congestive heart failure.
    Endocrine, 2003, Volume: 22, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Aged, 80 and over; Benzodiazepines; Female; H

2003
Decreased sleep in heart failure: are medications to blame?
    Archives of internal medicine, 2007, May-28, Volume: 167, Issue:10

    Topics: Adrenergic beta-Antagonists; Heart Failure; Humans; Melatonin; Sleep Initiation and Maintenance Diso

2007
The pineal affects life span in hamsters with heart disease.
    Physiology & behavior, 1997, Volume: 62, Issue:5

    Topics: Animals; Cardiomyopathies; Circadian Rhythm; Cricetinae; Heart Failure; Longevity; Male; Melatonin;

1997
Melatonin, a pineal hormone with antioxidant property, protects against adriamycin cardiomyopathy in rats.
    Life sciences, 1998, Volume: 63, Issue:7

    Topics: Animals; Antibiotics, Antineoplastic; Anticholesteremic Agents; Antioxidants; Doxorubicin; Heart; He

1998
[State of the neurohumoral regulatory system in circulatory insufficiency].
    Kardiologiia, 1976, Volume: 16, Issue:12

    Topics: 17-Ketosteroids; Adult; Aged; Aldosterone; Angiotensinogen; Coronary Disease; Cortisone; Endopeptida

1976