melatonin has been researched along with Carcinoma, Squamous Cell in 27 studies
Carcinoma, Squamous Cell: A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oesophageal squamous cell carcinoma (ESCC) is the sixth most common cause of cancer-associated death in the world and novel therapeutic alternatives are urgently warranted." | 5.43 | Melatonin enhances sensitivity to fluorouracil in oesophageal squamous cell carcinoma through inhibition of Erk and Akt pathway. ( Bai, L; Chen, DL; Chen, LZ; Ju, HQ; Lu, YX; Mo, HY; Sheng, H; Wang, DS; Wang, F; Wu, QN; Xie, D; Xu, RH; Yu, HE; Yun, JP; Zeng, ZL, 2016) |
| "Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy." | 4.40 | Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023) |
| "Oral squamous cell carcinomas are one of the most common cancers worldwide with aggressive behavior and poor prognosis." | 1.91 | Melatonin and erastin emerge synergistic anti-tumor effects on oral squamous cell carcinoma by inducing apoptosis, ferroptosis, and inhibiting autophagy through promoting ROS. ( Choi, WS; Li, X; Su, Y; Tao, Z; Wang, C; Wang, L; Zhu, W, 2023) |
| "Melatonin has been shown to have oncostatic effects in different types of cancers." | 1.91 | Intratumoral injection of melatonin enhances tumor regression in cell line-derived and patient-derived xenografts of head and neck cancer by increasing mitochondrial oxidative stress. ( Acuña-Castroviejo, D; Carriel, V; Escames, G; Fernández-Gil, BI; Fernández-Martínez, J; Florido, J; García-Tárraga, P; Garcia-Verdugo, JM; González-García, P; Guerra-Librero, A; López-Rodríguez, A; Martinez-Ruiz, L; Oppel, F; Rodriguez-Santana, C; Rusanova, I; Sánchez-Porras, D; Sudhoff, H; Ten-Steve, A, 2023) |
| "Melatonin receptors can inhibit breast and prostate cancers; however, little is known regarding their effects on oral squamous cell carcinoma." | 1.72 | Effects of melatonin receptor expression on prognosis and survival in oral squamous cell carcinoma patients. ( Hwang, DS; Jang, MA; Kim, GC; Kim, UK; Park, HK; Ryu, MH, 2022) |
| "Melatonin has been demonstrated to exhibit oncostatic effects." | 1.62 | Melatonin Suppresses Oral Squamous Cell Carcinomas Migration and Invasion through Blocking FGF19/FGFR 4 Signaling Pathway. ( Choi, WS; Su, Y; Wang, L, 2021) |
| "Melatonin treatment enhanced arecoline-induced ROS production, cytotoxicity, G2/M phase arrest, and cell apoptosis in OSCC cells." | 1.62 | Effects of melatonin to arecoline-induced reactive oxygen species production and DNA damage in oral squamous cell carcinoma. ( Chiu, KC; Hsia, SM; Lan, WC; Shieh, TM; Shih, YH; Tsai, BH; Wang, TH; Wu, LJ, 2021) |
| "The global prevalence of head and neck squamous cell carcinoma (HNSCC) remains high, and its prognosis poor." | 1.56 | Melatonin Exerts Anticancer Effects in Human Tongue Squamous Cell Carcinoma Cells by Promoting Autophagy. ( Ahn, YT; An, WG; Choi, SW; Jang, HB; Kim, JY; Lee, IW; Lee, JC; Sung, ES, 2020) |
| "Head and neck squamous cell carcinoma (HNSCC) clearly involves activation of the Akt mammalian target of rapamycin (mTOR) signalling pathway." | 1.48 | Combination of melatonin and rapamycin for head and neck cancer therapy: Suppression of AKT/mTOR pathway activation, and activation of mitophagy and apoptosis via mitochondrial function regulation. ( Acuña-Castroviejo, D; Carriel, V; Diaz-Casado, ME; Escames, G; Fernandez-Gil, BI; Florido, J; García-López, S; Guerra-Librero, A; López, LC; Martinez-Ruiz, L; Mendivil-Perez, M; Nieto, A; Ortega-Arellano, H; Reiter, RJ; Rusanova, I; Shen, YQ; Soto-Mercado, V, 2018) |
| "By assessing oral squamous cell carcinoma (OSCC) tissue arrays through immunohistochemistry, we examined whether aberrant LSD1 overexpression in OSCC is associated with poor prognosis." | 1.46 | Melatonin exerts anti-oral cancer effect via suppressing LSD1 in patient-derived tumor xenograft models. ( Chen, YW; Hsieh, CC; Lin, CK; Lin, GJ; Ma, KH; Shieh, YS; Sytwu, HK; Tsao, CH; Yang, CY, 2017) |
| "Oesophageal squamous cell carcinoma (ESCC) is the sixth most common cause of cancer-associated death in the world and novel therapeutic alternatives are urgently warranted." | 1.43 | Melatonin enhances sensitivity to fluorouracil in oesophageal squamous cell carcinoma through inhibition of Erk and Akt pathway. ( Bai, L; Chen, DL; Chen, LZ; Ju, HQ; Lu, YX; Mo, HY; Sheng, H; Wang, DS; Wang, F; Wu, QN; Xie, D; Xu, RH; Yu, HE; Yun, JP; Zeng, ZL, 2016) |
| "Treatment with melatonin prior to irradiation did not produce any significant change in apoptosis." | 1.40 | CCAR2 deficiency augments genotoxic stress-induced apoptosis in the presence of melatonin in non-small cell lung cancer cells. ( Jeong, JW; Kim, JE; Kim, W, 2014) |
| "We documented 10,799 incident skin cancers in 68,336 women in the Nurses' Health Study from June 1988 to June 2006 and examined the relationship between rotating night shifts and skin cancer." | 1.37 | Rotating night shifts and risk of skin cancer in the nurses' health study. ( Han, J; Li, TY; Qureshi, AA; Razavi, P; Schernhammer, ES, 2011) |
| "Treatment with melatonin and metformin and their combinations was followed by significantly lower tumor multiplicity and smaller size, longer latency period and survival of tumor-bearers." | 1.36 | [Melatonin and metformin inhibit skin carcinogenesis induced by benz(a)pyrene in mice]. ( Anisimov, VN; Deriabina, ON; Plotnikova, NA, 2010) |
| " EMF near fields exposure conditions were as follows: skin local peak specific absorption rate (SAR) 2." | 1.31 | Lack of promotion of 7,12-dimethylbenz[a]anthracene-initiated mouse skin carcinogenesis by 1.5 GHz electromagnetic near fields. ( Fujiwara, O; Imaida, K; Kato, K; Kuzutani, K; Ogiso, T; Shirai, T; Wang, J, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (7.41) | 18.7374 |
| 1990's | 1 (3.70) | 18.2507 |
| 2000's | 3 (11.11) | 29.6817 |
| 2010's | 10 (37.04) | 24.3611 |
| 2020's | 11 (40.74) | 2.80 |
| Authors | Studies |
|---|---|
| Park, HK | 1 |
| Ryu, MH | 1 |
| Hwang, DS | 1 |
| Kim, GC | 1 |
| Jang, MA | 1 |
| Kim, UK | 1 |
| Shigeishi, H | 1 |
| Yokoyama, S | 1 |
| Murodumi, H | 1 |
| Sakuma, M | 1 |
| Fukada, S | 1 |
| Okuda, S | 1 |
| Yamakado, N | 1 |
| Ono, S | 1 |
| Takechi, M | 1 |
| Ohta, K | 1 |
| Wang, L | 3 |
| Su, Y | 3 |
| Choi, WS | 3 |
| Wang, C | 2 |
| Tao, Z | 2 |
| Zhu, W | 2 |
| Li, X | 1 |
| Martinez-Ruiz, L | 2 |
| Florido, J | 2 |
| Rodriguez-Santana, C | 1 |
| López-Rodríguez, A | 1 |
| Guerra-Librero, A | 2 |
| Fernández-Gil, BI | 2 |
| García-Tárraga, P | 1 |
| Garcia-Verdugo, JM | 1 |
| Oppel, F | 1 |
| Sudhoff, H | 1 |
| Sánchez-Porras, D | 1 |
| Ten-Steve, A | 1 |
| Fernández-Martínez, J | 1 |
| González-García, P | 1 |
| Rusanova, I | 2 |
| Acuña-Castroviejo, D | 2 |
| Carriel, V | 2 |
| Escames, G | 2 |
| Shih, YH | 1 |
| Chiu, KC | 1 |
| Wang, TH | 1 |
| Lan, WC | 1 |
| Tsai, BH | 1 |
| Wu, LJ | 1 |
| Hsia, SM | 1 |
| Shieh, TM | 1 |
| Madapusi Balaji, T | 1 |
| Varadarajan, S | 1 |
| Jagannathan, R | 1 |
| Raj, AT | 1 |
| Sridhar, LP | 1 |
| Patil, S | 1 |
| Sung, ES | 1 |
| Kim, JY | 1 |
| Ahn, YT | 1 |
| Lee, IW | 1 |
| Choi, SW | 1 |
| Jang, HB | 1 |
| Lee, JC | 1 |
| An, WG | 1 |
| Salarić, I | 1 |
| Karmelić, I | 1 |
| Lovrić, J | 1 |
| Baždarić, K | 1 |
| Rožman, M | 1 |
| Čvrljević, I | 1 |
| Zajc, I | 1 |
| Brajdić, D | 1 |
| Macan, D | 1 |
| Yang, CY | 1 |
| Lin, CK | 1 |
| Tsao, CH | 1 |
| Hsieh, CC | 1 |
| Lin, GJ | 1 |
| Ma, KH | 1 |
| Shieh, YS | 1 |
| Sytwu, HK | 1 |
| Chen, YW | 1 |
| Fan, T | 1 |
| Pi, H | 1 |
| Li, M | 1 |
| Ren, Z | 1 |
| He, Z | 1 |
| Zhu, F | 1 |
| Tian, L | 1 |
| Tu, M | 1 |
| Xie, J | 1 |
| Liu, M | 1 |
| Li, Y | 1 |
| Tan, M | 1 |
| Li, G | 1 |
| Qing, W | 1 |
| Reiter, RJ | 2 |
| Yu, Z | 1 |
| Wu, H | 1 |
| Zhou, Z | 1 |
| Shen, YQ | 1 |
| García-López, S | 1 |
| Mendivil-Perez, M | 1 |
| Soto-Mercado, V | 1 |
| Ortega-Arellano, H | 1 |
| Diaz-Casado, ME | 1 |
| Nieto, A | 1 |
| López, LC | 1 |
| Kim, W | 1 |
| Jeong, JW | 1 |
| Kim, JE | 1 |
| Lu, YX | 1 |
| Chen, DL | 1 |
| Wang, DS | 1 |
| Chen, LZ | 1 |
| Mo, HY | 1 |
| Sheng, H | 1 |
| Bai, L | 1 |
| Wu, QN | 1 |
| Yu, HE | 1 |
| Xie, D | 1 |
| Yun, JP | 1 |
| Zeng, ZL | 1 |
| Wang, F | 1 |
| Ju, HQ | 1 |
| Xu, RH | 1 |
| Deriabina, ON | 1 |
| Plotnikova, NA | 1 |
| Anisimov, VN | 1 |
| Schernhammer, ES | 1 |
| Razavi, P | 1 |
| Li, TY | 1 |
| Qureshi, AA | 1 |
| Han, J | 1 |
| Mazzoccoli, G | 2 |
| Sothern, RB | 1 |
| Pazienza, V | 1 |
| Piepoli, A | 1 |
| Muscarella, LA | 1 |
| Giuliani, F | 1 |
| Tarquini, R | 2 |
| Durfort, T | 1 |
| Francois, JC | 1 |
| Di Bella, G | 1 |
| Colori, B | 1 |
| Zwirska-Korczala, K | 1 |
| Adamczyk-Sowa, M | 1 |
| Polaniak, R | 1 |
| Sowa, P | 1 |
| Birkner, E | 1 |
| Drzazga, Z | 1 |
| Brzozowski, T | 1 |
| Konturek, SJ | 1 |
| Dauchy, RT | 1 |
| Dauchy, EM | 1 |
| Davidson, LK | 1 |
| Krause, JA | 1 |
| Lynch, DT | 1 |
| Tirrell, PC | 1 |
| Tirrell, RP | 1 |
| Sauer, LA | 1 |
| Van der Riet, P | 1 |
| Blask, DE | 1 |
| Deĭneko, GM | 1 |
| Kvetnoĭ, IM | 1 |
| Bartsch, C | 1 |
| Kvetnoy, I | 1 |
| Kvetnaia, T | 1 |
| Bartsch, H | 1 |
| Molotkov, A | 1 |
| Franz, H | 1 |
| Raikhlin, N | 1 |
| Mecke, D | 1 |
| Imaida, K | 1 |
| Kuzutani, K | 1 |
| Wang, J | 1 |
| Fujiwara, O | 1 |
| Ogiso, T | 1 |
| Kato, K | 1 |
| Shirai, T | 1 |
| Wurtman, RJ | 1 |
2 reviews available for melatonin and Carcinoma, Squamous Cell
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
The effects of light on man and other mammals.
Topics: Animals; Bilirubin; Biological Clocks; Birds; Calcium; Carcinoma, Squamous Cell; Environment; Female | 1975 |
1 trial available for melatonin and Carcinoma, Squamous Cell
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
25 other studies available for melatonin and Carcinoma, Squamous Cell
| Article | Year |
|---|---|
Effects of melatonin receptor expression on prognosis and survival in oral squamous cell carcinoma patients.
Topics: Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Kaplan-Meier Estimate; Lymphatic Metastas | 2022 |
Melatonin enhances cisplatin-induced cell death through inhibition of DERL1 in mesenchymal-like CD44
Topics: Carcinoma, Squamous Cell; Cell Death; Cell Line, Tumor; Cell Proliferation; Cisplatin; Gene Expressi | 2022 |
Melatonin Suppresses Oral Squamous Cell Carcinomas Migration and Invasion through Blocking FGF19/FGFR 4 Signaling Pathway.
Topics: Carcinoma, Squamous Cell; Cell Movement; Cell Survival; Fibroblast Growth Factors; Gene Expression R | 2021 |
Tumor-associated macrophages facilitate oral squamous cell carcinomas migration and invasion by MIF/NLRP3/IL-1β circuit: A crosstalk interrupted by melatonin.
Topics: Animals; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Intramolecular Oxidoreductases; | 2023 |
Melatonin and erastin emerge synergistic anti-tumor effects on oral squamous cell carcinoma by inducing apoptosis, ferroptosis, and inhibiting autophagy through promoting ROS.
Topics: Animals; Apoptosis; Autophagy; Carcinoma, Squamous Cell; Disease Models, Animal; Ferroptosis; Head a | 2023 |
Intratumoral injection of melatonin enhances tumor regression in cell line-derived and patient-derived xenografts of head and neck cancer by increasing mitochondrial oxidative stress.
Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Cisplatin; Head and Neck Neoplasms; Heterografts; Humans | 2023 |
Effects of melatonin to arecoline-induced reactive oxygen species production and DNA damage in oral squamous cell carcinoma.
Topics: Areca; Arecoline; Carcinoma, Squamous Cell; DNA Damage; Humans; Melatonin; Mouth Neoplasms; Reactive | 2021 |
Hypothesizing the potential role of melatonin in inhibiting epithelial to mesenchymal transition in oral squamous cell carcinoma.
Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Epithelial-Mesenchymal Transition; Humans; Melatonin; Mo | 2020 |
Melatonin Exerts Anticancer Effects in Human Tongue Squamous Cell Carcinoma Cells by Promoting Autophagy.
Topics: Antineoplastic Agents; Apoptosis; Autophagy; Carcinoma, Squamous Cell; Cell Extracts; Cell Line, Tum | 2020 |
Salivary melatonin in oral squamous cell carcinoma patients.
Topics: Biomarkers, Tumor; Carcinoma, Squamous Cell; Case-Control Studies; Female; Humans; Male; Melatonin; | 2021 |
Melatonin exerts anti-oral cancer effect via suppressing LSD1 in patient-derived tumor xenograft models.
Topics: Acetylation; Animals; Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Cycle | 2017 |
Inhibiting MT2-TFE3-dependent autophagy enhances melatonin-induced apoptosis in tongue squamous cell carcinoma.
Topics: Adult; Aged; Animals; Antioxidants; Apoptosis; Autophagy; Basic Helix-Loop-Helix Leucine Zipper Tran | 2018 |
Combination of melatonin and rapamycin for head and neck cancer therapy: Suppression of AKT/mTOR pathway activation, and activation of mitophagy and apoptosis via mitochondrial function regulation.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Squamous Cell; Cell L | 2018 |
CCAR2 deficiency augments genotoxic stress-induced apoptosis in the presence of melatonin in non-small cell lung cancer cells.
Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma; Antioxidants; Apoptosis; Blotting, Western; Ca | 2014 |
Melatonin enhances sensitivity to fluorouracil in oesophageal squamous cell carcinoma through inhibition of Erk and Akt pathway.
Topics: Carcinoma, Squamous Cell; Cell Death; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Syne | 2016 |
[Melatonin and metformin inhibit skin carcinogenesis induced by benz(a)pyrene in mice].
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Carcinoma, Squamous Cell; Catalase; Central Nervous | 2010 |
Rotating night shifts and risk of skin cancer in the nurses' health study.
Topics: Adult; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Confounding Factors, Epidemiologic; Female; | 2011 |
Circadian aspects of growth hormone-insulin-like growth factor axis function in patients with lung cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous | 2012 |
Chronodisruption in lung cancer and possible therapeutic approaches.
Topics: Adenocarcinoma; Adult; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Chronobiology Disor | 2011 |
The Di Bella Method (DBM) improved survival, objective response and performance status in a retrospective observational clinical study on 23 tumours of the head and neck.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Antioxidants; Calcium; Carcinoma | 2012 |
Influence of extremely-low-frequency magnetic field on antioxidative melatonin properties in AT478 murine squamous cell carcinoma culture.
Topics: Animals; Antioxidants; Carcinoma, Squamous Cell; Cell Line, Tumor; Electromagnetic Fields; Female; G | 2004 |
Inhibition of fatty acid transport and proliferative activity in tissue-isolated human squamous cell cancer xenografts perfused in situ with melatonin or eicosapentaenoic or conjugated linoleic acids.
Topics: Animals; Antineoplastic Agents; Biological Transport; Carcinoma, Squamous Cell; Cell Proliferation; | 2007 |
[Endocrine cells in human laryngeal tumors (ectopic hormone secretion)].
Topics: Carcinoma, Squamous Cell; Cell Differentiation; Follicle Stimulating Hormone; Growth Hormone; Hormon | 1983 |
Nocturnal urinary 6-sulfatoxymelatonin and proliferating cell nuclear antigen-immunopositive tumor cells show strong positive correlations in patients with gastrointestinal and lung cancer.
Topics: Adenocarcinoma; Aged; Carcinoma, Squamous Cell; Gastrointestinal Neoplasms; Humans; Immunoenzyme Tec | 1997 |
Lack of promotion of 7,12-dimethylbenz[a]anthracene-initiated mouse skin carcinogenesis by 1.5 GHz electromagnetic near fields.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenocorticotropic Hormone; Animals; Carcinogens; Carcinoma, Squa | 2001 |