melatonin has been researched along with Carcinoma, Renal Cell in 11 studies
Carcinoma, Renal Cell: A heterogeneous group of sporadic or hereditary carcinoma derived from cells of the KIDNEYS. There are several subtypes including the clear cells, the papillary, the chromophobe, the collecting duct, the spindle cells (sarcomatoid), or mixed cell-type carcinoma.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Melatonin was given orally at 20 mg/day in the evening for at least 2 months." | 2.70 | Anti-angiogenic activity of melatonin in advanced cancer patients. ( Bucovec, R; Conti, A; Lissoni, P; Maestroni, GJ; Malugani, F; Rovelli, F, 2001) |
| "Metabolic alteration drives renal cell carcinoma (RCC) development, while the impact of melatonin (MLT), a neurohormone secreted during darkness, on RCC cell growth and underlying mechanisms remains unclear." | 1.91 | Melatonin suppresses Akt/mTOR/S6K activity, induces cell apoptosis, and synergistically inhibits cell growth with sunitinib in renal carcinoma cells via reversing Warburg effect. ( Bai, JY; Chen, YH; Guo, P; Jiang, YF; Ma, JB; Wang, X; Xue, KH; Zhang, DZ; Zhu, ZJ, 2023) |
| "The study was performed on metastatic renal cell cancer patients." | 1.30 | Immunomodulatory effects of IL-12 in relation to the pineal endocrine function in metastatic cancer patients. ( Fumagalli, L; Giani, L; Lissoni, P; Mandalà, M; Rovelli, F, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (36.36) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 3 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Jiang, A | 1 |
| Cai, C | 1 |
| Yang, Y | 1 |
| Cui, Y | 1 |
| Liu, W | 1 |
| Pang, Q | 1 |
| Wu, Z | 1 |
| Liu, B | 1 |
| Qu, L | 1 |
| Luo, P | 1 |
| Wang, A | 1 |
| Wang, L | 1 |
| Xue, KH | 1 |
| Jiang, YF | 1 |
| Bai, JY | 1 |
| Zhang, DZ | 1 |
| Chen, YH | 1 |
| Ma, JB | 1 |
| Zhu, ZJ | 1 |
| Wang, X | 1 |
| Guo, P | 1 |
| Wen, YC | 1 |
| Lin, YW | 2 |
| Chu, CY | 2 |
| Yang, YC | 2 |
| Yang, SF | 2 |
| Liu, YF | 1 |
| Hsiao, M | 2 |
| Lee, WJ | 2 |
| Chien, MH | 2 |
| Lee, LM | 1 |
| Tan, P | 1 |
| Chen, WY | 1 |
| Lissoni, P | 4 |
| Malugani, F | 2 |
| Malysheva, O | 1 |
| Kozlov, V | 1 |
| Laudon, M | 1 |
| Conti, A | 2 |
| Maestroni, G | 1 |
| Song, Y | 1 |
| Tam, PC | 1 |
| Poon, AM | 1 |
| Brown, GM | 1 |
| Pang, SF | 1 |
| Neri, B | 1 |
| Fiorelli, C | 1 |
| Moroni, F | 1 |
| Nicita, G | 1 |
| Paoletti, MC | 1 |
| Ponchietti, R | 1 |
| Raugei, A | 1 |
| Santoni, G | 1 |
| Trippitelli, A | 1 |
| Grechi, G | 1 |
| Taverna, G | 1 |
| Trinchieri, A | 1 |
| Mandressi, A | 1 |
| Del Nero, A | 1 |
| Mangiarotti, B | 1 |
| Antonelli, D | 1 |
| Chisena, S | 1 |
| Pisani, E | 1 |
| Mandalà, M | 2 |
| Brivio, F | 1 |
| Rovelli, F | 2 |
| Giani, L | 1 |
| Fumagalli, L | 1 |
| Bucovec, R | 1 |
| Maestroni, GJ | 1 |
4 trials available for melatonin and Carcinoma, Renal Cell
| Article | Year |
|---|---|
Neuroimmunotherapy of untreatable metastatic solid tumors with subcutaneous low-dose interleukin-2, melatonin and naltrexone: modulation of interleukin-2-induced antitumor immunity by blocking the opioid system.
Topics: Adjuvants, Immunologic; Aged; Antineoplastic Agents; Carcinoma, Neuroendocrine; Carcinoma, Renal Cel | 2002 |
Modulation of human lymphoblastoid interferon activity by melatonin in metastatic renal cell carcinoma. A phase II study.
Topics: Adult; Aged; Carcinoma, Renal Cell; Female; Humans; Interferon-alpha; Kidney Neoplasms; Male; Melato | 1994 |
Abrogation of the negative influence of opioids on IL-2 immunotherapy of renal cell cancer by melatonin.
Topics: Adjuvants, Immunologic; Adult; Analgesics, Opioid; Carcinoma, Renal Cell; Female; Follow-Up Studies; | 2000 |
Anti-angiogenic activity of melatonin in advanced cancer patients.
Topics: Adult; Aged; Bone Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; C | 2001 |
7 other studies available for melatonin and Carcinoma, Renal Cell
| Article | Year |
|---|---|
Deciphering the Role of Melatonin-Related Signatures in Tumor Immunity and the Prognosis of Clear Cell Renal Cell Carcinoma.
Topics: Algorithms; Carcinoma, Renal Cell; DNA Copy Number Variations; Humans; Kidney Neoplasms; Melatonin; | 2023 |
Melatonin suppresses Akt/mTOR/S6K activity, induces cell apoptosis, and synergistically inhibits cell growth with sunitinib in renal carcinoma cells via reversing Warburg effect.
Topics: Antioxidants; Apoptosis; Carcinoma, Renal Cell; Chromatography, Liquid; Humans; Kidney Neoplasms; Me | 2023 |
Melatonin-triggered post-transcriptional and post-translational modifications of ADAMTS1 coordinately retard tumorigenesis and metastasis of renal cell carcinoma.
Topics: ADAMTS1 Protein; Animals; Carcinogenesis; Carcinoma, Renal Cell; Cell Line, Tumor; Humans; Kidney Ne | 2020 |
Melatonin inhibits MMP-9 transactivation and renal cell carcinoma metastasis by suppressing Akt-MAPKs pathway and NF-κB DNA-binding activity.
Topics: Animals; Carcinoma, Renal Cell; DNA, Neoplasm; Gene Expression Regulation, Enzymologic; Gene Express | 2016 |
2-[125I]iodomelatonin-binding sites in the human kidney and the effect of guanosine 5'-O-(3-thiotriphosphate).
Topics: Adult; Aged; Autoradiography; Binding Sites; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Fe | 1995 |
Variation in nocturnal urinary excretion of melatonin in a group of patients older than 55 years suffering from urogenital tract disorders.
Topics: Aged; Aged, 80 and over; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Circadian Rhythm; Fema | 1997 |
Immunomodulatory effects of IL-12 in relation to the pineal endocrine function in metastatic cancer patients.
Topics: Adjuvants, Immunologic; Carcinoma, Renal Cell; Humans; Immunity, Innate; Immunotherapy; Inflammation | 1998 |