melatonin has been researched along with Carcinoma, Neuroendocrine in 2 studies
Carcinoma, Neuroendocrine: A group of carcinomas which share a characteristic morphology, often being composed of clusters and trabecular sheets of round blue cells, granular chromatin, and an attenuated rim of poorly demarcated cytoplasm. Neuroendocrine tumors include carcinoids, small (oat) cell carcinomas, medullary carcinoma of the thyroid, Merkel cell tumor, cutaneous neuroendocrine carcinoma, pancreatic islet cell tumors, and pheochromocytoma. Neurosecretory granules are found within the tumor cells. (Segen, Dictionary of Modern Medicine, 1992)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Melatonin treatment dramatically reduced the number of prostate cancer cells and stopped cell cycle progression in both LNCaP and PC3 cells." | 1.33 | Melatonin reduces prostate cancer cell growth leading to neuroendocrine differentiation via a receptor and PKA independent mechanism. ( León, J; Manchester, L; Mayo, JC; Reiter, RJ; Sainz, RM; Tan, DX, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lissoni, P | 1 |
| Malugani, F | 1 |
| Malysheva, O | 1 |
| Kozlov, V | 1 |
| Laudon, M | 1 |
| Conti, A | 1 |
| Maestroni, G | 1 |
| Sainz, RM | 1 |
| Mayo, JC | 1 |
| Tan, DX | 1 |
| León, J | 1 |
| Manchester, L | 1 |
| Reiter, RJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot, Open-label Study to Evaluate the Effects of a Prostate Health Formulation on Scores Attained From the International Prostate Symptom Score (I-PSS) Questionnaire Among Overall Healthy Male Participants Who Report Lower Urinary Tract Complaints[NCT02886832] | 30 participants (Anticipated) | Interventional | 2016-09-21 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for melatonin and Carcinoma, Neuroendocrine
| Article | Year |
|---|---|
Neuroimmunotherapy of untreatable metastatic solid tumors with subcutaneous low-dose interleukin-2, melatonin and naltrexone: modulation of interleukin-2-induced antitumor immunity by blocking the opioid system.
Topics: Adjuvants, Immunologic; Aged; Antineoplastic Agents; Carcinoma, Neuroendocrine; Carcinoma, Renal Cel | 2002 |
1 other study available for melatonin and Carcinoma, Neuroendocrine
| Article | Year |
|---|---|
Melatonin reduces prostate cancer cell growth leading to neuroendocrine differentiation via a receptor and PKA independent mechanism.
Topics: Adjuvants, Immunologic; Carcinoma, Neuroendocrine; Cell Differentiation; Cell Division; Cell Line, T | 2005 |