melatonin has been researched along with Cancer of Skin in 37 studies
Excerpt | Relevance | Reference |
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" One hundred patients recently diagnosed with non-metastatic uveal melanoma will be randomized to either treatment with adjuvant melatonin 20 mg (4 tablets of 5 mg) at 10 pm for 5 years, or to standard follow-up (control group)." | 9.69 | Adjuvant melatonin for uveal melanoma (AMUM): protocol for a randomized open-label phase III study. ( Hagström, A; Kal Omar, R; Stålhammar, G, 2023) |
"Melatonin significantly and synergistically enhanced vemurafenib-mediated inhibitions of proliferation, colony formation, migration and invasion and promoted vemurafenib-induced apoptosis, cell cycle arresting and stemness weakening in melanoma cells." | 7.91 | Melatonin synergizes BRAF-targeting agent vemurafenib in melanoma treatment by inhibiting iNOS/hTERT signaling and cancer-stem cell traits. ( Chen, M; Deng, W; Diao, C; Fan, W; Guo, P; Guo, W; Hao, J; Hu, S; Jiang, K; Li, L; Li, Y; Long, Q; Qin, G; Qin, L; Ren, Y; Tang, R; Tian, C; Wang, J; Yang, Q; Yu, W; Zhang, C; Zhang, X; Zhou, P; Zhu, T; Zou, L, 2019) |
"Results are given of daily excretion levels of 6-oxymelatonin, thymic serum factor (FTS), and cortisol in the blood of 140 healthy subjects and 90 patients with skin melanoma, ranging from 20 to 49 years of age." | 7.67 | Melatonin, thymic serum factor, and cortisol levels in healthy subjects of different age and patients with skin melanoma. ( Grinevich, YA; Labunetz, IF, 1986) |
" One hundred patients recently diagnosed with non-metastatic uveal melanoma will be randomized to either treatment with adjuvant melatonin 20 mg (4 tablets of 5 mg) at 10 pm for 5 years, or to standard follow-up (control group)." | 5.69 | Adjuvant melatonin for uveal melanoma (AMUM): protocol for a randomized open-label phase III study. ( Hagström, A; Kal Omar, R; Stålhammar, G, 2023) |
"Melanoma is a leading cause of cancer deaths worldwide." | 5.62 | Mitochondrial function is controlled by melatonin and its metabolites in vitro in human melanoma cells. ( Bilska, B; Kleszczyński, K; Piotrowska, A; Pyza, E; Reiter, RJ; Schedel, F; Slominski, AT; Stefan, J; Steinbrink, K; Tulic, MK; Zmijewski, M, 2021) |
"Melatonin and Kiss1 were shown to be nvolved in tumor suppression." | 5.56 | The effects of daylight exposure on melatonin levels, Kiss1 expression, and melanoma formation in mice. ( Alptekin, D; Kaplan, H; Kasap, H; Lüleyap, U; Pazarci, P; Pelit, A; Singirik, E; Yegani, A; Yilmaz, M, 2020) |
"By melatonin treatment this ratio was similar to control values." | 5.56 | Restraint stress abates the antioxidant potential of melatonin on dimethyl benz (a) anthracene (DMBA) induced carcinogenesis. ( Aljaser, F; Alsharidah, AS; Azmi, AS; Banu, N; Fatima, S; Khan, SA; Muqbil, I, 2020) |
"Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy." | 4.40 | Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023) |
"Melatonin significantly and synergistically enhanced vemurafenib-mediated inhibitions of proliferation, colony formation, migration and invasion and promoted vemurafenib-induced apoptosis, cell cycle arresting and stemness weakening in melanoma cells." | 3.91 | Melatonin synergizes BRAF-targeting agent vemurafenib in melanoma treatment by inhibiting iNOS/hTERT signaling and cancer-stem cell traits. ( Chen, M; Deng, W; Diao, C; Fan, W; Guo, P; Guo, W; Hao, J; Hu, S; Jiang, K; Li, L; Li, Y; Long, Q; Qin, G; Qin, L; Ren, Y; Tang, R; Tian, C; Wang, J; Yang, Q; Yu, W; Zhang, C; Zhang, X; Zhou, P; Zhu, T; Zou, L, 2019) |
"Results are given of daily excretion levels of 6-oxymelatonin, thymic serum factor (FTS), and cortisol in the blood of 140 healthy subjects and 90 patients with skin melanoma, ranging from 20 to 49 years of age." | 3.67 | Melatonin, thymic serum factor, and cortisol levels in healthy subjects of different age and patients with skin melanoma. ( Grinevich, YA; Labunetz, IF, 1986) |
"Melanoma is the most aggressive type of skin cancer, with a greater risk of metastasis and a higher prevalence and mortality rate." | 3.01 | Melatonin as a Repurposed Drug for Melanoma Treatment. ( Pathipaka, R; Sahu, RP; Thyagarajan, A, 2023) |
"Melatonin was shown to have protective effects when applied before UVR, but no effect if applied after exposure." | 2.50 | Melatonin's protective effect against UV radiation: a systematic review of clinical and experimental studies. ( Gögenur, I; Pommergaard, HC; Rosenberg, J; Scheuer, C, 2014) |
"Melanoma is a less common type of skin cancer yet more aggressive often with a lethal ending." | 2.50 | Running for time: circadian rhythms and melanoma. ( Ilić, N; Jurišić, D; Kraljević Pavelić, S; Markova-Car, EP, 2014) |
"Melatonin has been experimentally implicated in skin functions such as hair growth cycling, fur pigmentation, and melanoma control, and melatonin receptors are expressed in several skin cells including normal and malignant keratinocytes, melanocytes, and fibroblasts." | 2.43 | On the role of melatonin in skin physiology and pathology. ( Fischer, TW; Semak, I; Slominski, A; Slominski, RM; Tobin, DJ; Wortsman, J; Zbytek, B; Zmijewski, MA, 2005) |
"Non-melanoma skin cancer (NMSC) is the most common cancer in the world." | 1.91 | The environmental carcinogen benzo[a]pyrene regulates epigenetic reprogramming and metabolic rewiring in a two-stage mouse skin carcinogenesis model. ( Chou, P; Dina Kuo, HC; Kong, AN; Mary Peter, R; Ramirez, CN; Sargsyan, D; Sarwar, MS; Shannar, A; Su, X; Wang, Y; Wu, R; Yang, Y; Yin, R, 2023) |
"Melanoma is a leading cause of cancer deaths worldwide." | 1.62 | Mitochondrial function is controlled by melatonin and its metabolites in vitro in human melanoma cells. ( Bilska, B; Kleszczyński, K; Piotrowska, A; Pyza, E; Reiter, RJ; Schedel, F; Slominski, AT; Stefan, J; Steinbrink, K; Tulic, MK; Zmijewski, M, 2021) |
"Melatonin and Kiss1 were shown to be nvolved in tumor suppression." | 1.56 | The effects of daylight exposure on melatonin levels, Kiss1 expression, and melanoma formation in mice. ( Alptekin, D; Kaplan, H; Kasap, H; Lüleyap, U; Pazarci, P; Pelit, A; Singirik, E; Yegani, A; Yilmaz, M, 2020) |
"By melatonin treatment this ratio was similar to control values." | 1.56 | Restraint stress abates the antioxidant potential of melatonin on dimethyl benz (a) anthracene (DMBA) induced carcinogenesis. ( Aljaser, F; Alsharidah, AS; Azmi, AS; Banu, N; Fatima, S; Khan, SA; Muqbil, I, 2020) |
"We documented 10,799 incident skin cancers in 68,336 women in the Nurses' Health Study from June 1988 to June 2006 and examined the relationship between rotating night shifts and skin cancer." | 1.37 | Rotating night shifts and risk of skin cancer in the nurses' health study. ( Han, J; Li, TY; Qureshi, AA; Razavi, P; Schernhammer, ES, 2011) |
"Treatment with melatonin and metformin and their combinations was followed by significantly lower tumor multiplicity and smaller size, longer latency period and survival of tumor-bearers." | 1.36 | [Melatonin and metformin inhibit skin carcinogenesis induced by benz(a)pyrene in mice]. ( Anisimov, VN; Deriabina, ON; Plotnikova, NA, 2010) |
"Melatonin has oncostatic effects on several types of cancer (breast, prostate, and colorectal cancers), while it can be self-defeating in others, such as lymphoma." | 1.35 | Effects of exogenous melatonin and circadian synchronization on tumor progression in melanoma-bearing C57BL6 mice. ( Alvarez, N; Madrid, JA; Otálora, BB; Rol, MA; Vicente, V, 2008) |
"Melatonin treatment supressed MDA and catalase levels in blood serum but not in tumor tissue." | 1.34 | [Melatonin suppresses benz(a)pyrene-induced carcinogenesis in mice]. ( Anisimov, VN; Plotnikova, NA; Vesnushkin, GM, 2007) |
" One group of animals was exposed to Digital Advanced Mobile Phone System (DAMPS)-type RFR, the other group to Global System for Mobile (GSM)-type RFR at a nominal average specific absorption rate of 0." | 1.32 | Effects of mobile phone radiation on UV-induced skin tumourigenesis in ornithine decarboxylase transgenic and non-transgenic mice. ( Alhonen, L; Heikkinen, P; Huuskonen, H; Juutilainen, J; Komulainen, H; Kosma, VM; Kumlin, T; Laitinen, JT; Lang, S; Puranen, L, 2003) |
" EMF near fields exposure conditions were as follows: skin local peak specific absorption rate (SAR) 2." | 1.31 | Lack of promotion of 7,12-dimethylbenz[a]anthracene-initiated mouse skin carcinogenesis by 1.5 GHz electromagnetic near fields. ( Fujiwara, O; Imaida, K; Kato, K; Kuzutani, K; Ogiso, T; Shirai, T; Wang, J, 2001) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 6 (16.22) | 18.7374 |
1990's | 3 (8.11) | 18.2507 |
2000's | 5 (13.51) | 29.6817 |
2010's | 16 (43.24) | 24.3611 |
2020's | 7 (18.92) | 2.80 |
Authors | Studies |
---|---|
Pathipaka, R | 1 |
Thyagarajan, A | 1 |
Sahu, RP | 1 |
Kal Omar, R | 1 |
Hagström, A | 1 |
Stålhammar, G | 1 |
Sarwar, MS | 1 |
Ramirez, CN | 1 |
Dina Kuo, HC | 1 |
Chou, P | 1 |
Wu, R | 1 |
Sargsyan, D | 1 |
Yang, Y | 1 |
Shannar, A | 1 |
Mary Peter, R | 1 |
Yin, R | 1 |
Wang, Y | 1 |
Su, X | 1 |
Kong, AN | 1 |
Pazarci, P | 1 |
Kaplan, H | 1 |
Alptekin, D | 1 |
Yilmaz, M | 1 |
Lüleyap, U | 1 |
Singirik, E | 1 |
Pelit, A | 1 |
Kasap, H | 1 |
Yegani, A | 1 |
Muqbil, I | 1 |
Fatima, S | 1 |
Azmi, AS | 1 |
Alsharidah, AS | 1 |
Khan, SA | 1 |
Aljaser, F | 1 |
Banu, N | 1 |
Bilska, B | 1 |
Schedel, F | 1 |
Piotrowska, A | 1 |
Stefan, J | 1 |
Zmijewski, M | 1 |
Pyza, E | 1 |
Reiter, RJ | 4 |
Steinbrink, K | 1 |
Slominski, AT | 4 |
Tulic, MK | 1 |
Kleszczyński, K | 1 |
Hardeland, R | 1 |
Zmijewski, MA | 2 |
Slominski, RM | 2 |
Paus, R | 1 |
Pourhanifeh, MH | 1 |
Mahdavinia, M | 1 |
Asemi, Z | 1 |
Hao, J | 1 |
Fan, W | 1 |
Li, Y | 1 |
Tang, R | 1 |
Tian, C | 1 |
Yang, Q | 1 |
Zhu, T | 1 |
Diao, C | 1 |
Hu, S | 1 |
Chen, M | 2 |
Guo, P | 1 |
Long, Q | 1 |
Zhang, C | 1 |
Qin, G | 1 |
Yu, W | 1 |
Li, L | 1 |
Qin, L | 1 |
Wang, J | 2 |
Zhang, X | 1 |
Ren, Y | 1 |
Zhou, P | 1 |
Zou, L | 1 |
Jiang, K | 1 |
Guo, W | 1 |
Deng, W | 1 |
Scheuer, C | 1 |
Pommergaard, HC | 1 |
Rosenberg, J | 1 |
Gögenur, I | 1 |
Markova-Car, EP | 1 |
Jurišić, D | 1 |
Ilić, N | 1 |
Kraljević Pavelić, S | 1 |
Kim, TK | 2 |
Lin, Z | 2 |
Tidwell, WJ | 1 |
Li, W | 2 |
Goswami, S | 1 |
Haldar, C | 1 |
Gutierrez, D | 1 |
Arbesman, J | 1 |
van der Rhee, HJ | 1 |
de Vries, E | 1 |
Coebergh, JW | 1 |
Kvaskoff, M | 1 |
Weinstein, P | 1 |
Thestrup-Pedersen, K | 1 |
Søndergaard, K | 1 |
Deriabina, ON | 1 |
Plotnikova, NA | 3 |
Anisimov, VN | 3 |
Schernhammer, ES | 1 |
Razavi, P | 1 |
Li, TY | 1 |
Qureshi, AA | 1 |
Han, J | 1 |
Langan, EA | 1 |
Rhodes, LE | 1 |
Man'cheva, TA | 1 |
Demidov, DV | 1 |
Kharitonova, TV | 1 |
Pashkevich, IV | 1 |
Heikkinen, P | 1 |
Kosma, VM | 1 |
Alhonen, L | 1 |
Huuskonen, H | 1 |
Komulainen, H | 1 |
Kumlin, T | 1 |
Laitinen, JT | 1 |
Lang, S | 1 |
Puranen, L | 1 |
Juutilainen, J | 1 |
Slominski, A | 1 |
Fischer, TW | 1 |
Wortsman, J | 1 |
Semak, I | 1 |
Zbytek, B | 1 |
Tobin, DJ | 1 |
Vesnushkin, GM | 1 |
Otálora, BB | 1 |
Madrid, JA | 1 |
Alvarez, N | 1 |
Vicente, V | 1 |
Rol, MA | 1 |
Labunets, IF | 1 |
Grinevich, IuA | 1 |
Knysh, IT | 1 |
Vasiliuk, AN | 1 |
Matsumoto, J | 1 |
Ishikawa, T | 1 |
Masahito, P | 1 |
Takayama, S | 1 |
Taylor, JD | 1 |
Tchen, TT | 1 |
Zhen, B | 1 |
Murphy, JR | 1 |
Cohn, BA | 1 |
Moulder, JE | 1 |
Imaida, K | 1 |
Kuzutani, K | 1 |
Fujiwara, O | 1 |
Ogiso, T | 1 |
Kato, K | 1 |
Shirai, T | 1 |
Wurtman, RJ | 1 |
Grinevich, YA | 1 |
Labunetz, IF | 1 |
Strafuss, AC | 1 |
Dommert, AR | 1 |
Tumbleson, ME | 1 |
Middleton, CC | 1 |
Ghosh, BC | 1 |
el-Domeiri, AA | 1 |
Das Gupta, TK | 1 |
12 reviews available for melatonin and Cancer of Skin
Article | Year |
---|---|
Melatonin as a Repurposed Drug for Melanoma Treatment.
Topics: Animals; Melanoma, Experimental; Melatonin; Pineal Gland; Signal Transduction; Skin Neoplasms | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Melatonin: A Cutaneous Perspective on its Production, Metabolism, and Functions.
Topics: Animals; Antineoplastic Agents; Hair Follicle; Humans; Melatonin; Radiation-Protective Agents; Recep | 2018 |
Potential use of melatonin in skin cancer treatment: A review of current biological evidence.
Topics: Antineoplastic Agents; Antioxidants; Apoptosis; Humans; Melanoma; Melatonin; Oxidative Stress; React | 2019 |
Melatonin's protective effect against UV radiation: a systematic review of clinical and experimental studies.
Topics: Animals; Humans; MEDLINE; Melatonin; Neoplasms, Radiation-Induced; Skin Neoplasms; Sunscreening Agen | 2014 |
Running for time: circadian rhythms and melanoma.
Topics: Arylalkylamine N-Acetyltransferase; Circadian Rhythm; Gene Expression Regulation, Neoplastic; Humans | 2014 |
Melatonin as a possible antidote to UV radiation induced cutaneous damages and immune-suppression: An overview.
Topics: Animals; Antidotes; Antioxidants; Apoptosis; Humans; Melatonin; Skin; Skin Neoplasms; Ultraviolet Ra | 2015 |
Circadian Dysrhythmias, Physiological Aberrations, and the Link to Skin Cancer.
Topics: Circadian Rhythm; CLOCK Proteins; DNA Damage; DNA Repair; Gene Expression; Humans; Melanoma; Melaton | 2016 |
On the role of melatonin in skin physiology and pathology.
Topics: Amino Acid Sequence; Animals; Humans; Melatonin; Molecular Sequence Data; Phenotype; Receptors, Mela | 2005 |
Melatonin and the skin: from frog to human.
Topics: Amphibians; Animals; Humans; Melanoma; Melatonin; Skin Neoplasms; Skin Pigmentation | 1996 |
Power-frequency fields and cancer.
Topics: Animals; Breast Neoplasms; Cell Division; Chromosome Aberrations; Electromagnetic Fields; Environmen | 1998 |
The effects of light on man and other mammals.
Topics: Animals; Bilirubin; Biological Clocks; Birds; Calcium; Carcinoma, Squamous Cell; Environment; Female | 1975 |
2 trials available for melatonin and Cancer of Skin
Article | Year |
---|---|
Adjuvant melatonin for uveal melanoma (AMUM): protocol for a randomized open-label phase III study.
Topics: Adult; Clinical Trials, Phase III as Topic; Humans; Melanoma; Melatonin; Randomized Controlled Trial | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
24 other studies available for melatonin and Cancer of Skin
Article | Year |
---|---|
The environmental carcinogen benzo[a]pyrene regulates epigenetic reprogramming and metabolic rewiring in a two-stage mouse skin carcinogenesis model.
Topics: Animals; Benzo(a)pyrene; Carcinogenesis; Carcinogens, Environmental; Epigenesis, Genetic; Melatonin; | 2023 |
The effects of daylight exposure on melatonin levels, Kiss1 expression, and melanoma formation in mice.
Topics: Animals; Animals, Newborn; Female; Gene Expression Regulation; Hypothalamus; Kisspeptins; Melanoma; | 2020 |
Restraint stress abates the antioxidant potential of melatonin on dimethyl benz (a) anthracene (DMBA) induced carcinogenesis.
Topics: Animals; Anthracenes; Antioxidants; Carcinogenesis; Carcinogens; Male; Melatonin; Oxidative Stress; | 2020 |
Mitochondrial function is controlled by melatonin and its metabolites in vitro in human melanoma cells.
Topics: Antineoplastic Agents; Biotransformation; Cell Line, Tumor; Cell Proliferation; Energy Metabolism; H | 2021 |
Melatonin synergizes BRAF-targeting agent vemurafenib in melanoma treatment by inhibiting iNOS/hTERT signaling and cancer-stem cell traits.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apopto | 2019 |
Melatonin and its metabolites accumulate in the human epidermis in vivo and inhibit proliferation and tyrosinase activity in epidermal melanocytes in vitro.
Topics: 5-Methoxytryptamine; Adult; Age Factors; Aged; Aged, 80 and over; Black or African American; Cell Pr | 2015 |
N1-Acetyl-5-Methoxykynuramine (AMK) is produced in the human epidermis and shows antiproliferative effects.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Black or African American; Cell Line; Cell Line, Tumor; | 2015 |
Regular sun exposure benefits health.
Topics: Animals; Circadian Rhythm; Environmental Exposure; Europe; Female; Health; Humans; Male; Melanoma; M | 2016 |
Are some melanomas caused by artificial light?
Topics: Global Health; Humans; Incidence; Lighting; Melanoma; Melatonin; Risk Factors; Skin Neoplasms | 2010 |
Melatonin used for tanning induces and augments lentigines and naevi.
Topics: Adult; Humans; Injections; Lentigo; Male; Melatonin; Nevus; Skin; Skin Neoplasms; Sunbathing | 2010 |
[Melatonin and metformin inhibit skin carcinogenesis induced by benz(a)pyrene in mice].
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Carcinoma, Squamous Cell; Catalase; Central Nervous | 2010 |
Rotating night shifts and risk of skin cancer in the nurses' health study.
Topics: Adult; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Confounding Factors, Epidemiologic; Female; | 2011 |
Melanotropic peptides: what exactly is meant by "melanotan"?
Topics: alpha-MSH; Humans; Injections; Lentigo; Melatonin; Nevus; Risk Assessment; Skin Neoplasms; Sunbathin | 2011 |
Melatonin and metformin inhibit skin carcinogenesis and lipid peroxidation induced by benz(a)pyrene in female mice.
Topics: Animals; Antioxidants; Benzo(a)pyrene; Cell Transformation, Neoplastic; Female; Lipid Peroxidation; | 2011 |
Effects of mobile phone radiation on UV-induced skin tumourigenesis in ornithine decarboxylase transgenic and non-transgenic mice.
Topics: Animals; Biogenic Polyamines; Cell Phone; Cocarcinogenesis; Female; Humans; Melatonin; Mice; Mice, T | 2003 |
[Melatonin suppresses benz(a)pyrene-induced carcinogenesis in mice].
Topics: Animals; Antioxidants; Benzo(a)pyrene; Catalase; Cell Transformation, Neoplastic; Female; Malondiald | 2007 |
Effects of exogenous melatonin and circadian synchronization on tumor progression in melanoma-bearing C57BL6 mice.
Topics: Animals; Body Temperature; Circadian Rhythm; Disease Progression; Light; Male; Melanoma, Experimenta | 2008 |
[Functional characteristics of the endocrine glands in skin melanoma patients].
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Female; Humans; Hydrocortisone; Male; Melanocyte | 1984 |
Clonal heterogeneity in physiological properties of melanized cells induced from goldfish erythrophoroma cell lines.
Topics: Animals; Cell Differentiation; Cell Line; Clone Cells; Cyprinidae; Epinephrine; Goldfish; Melanocyte | 1984 |
Sample size determination for an exponential survival model with an unrestricted covariate.
Topics: Computer Simulation; Factor Analysis, Statistical; Humans; Mathematical Computing; Melanoma; Melaton | 1994 |
Lack of promotion of 7,12-dimethylbenz[a]anthracene-initiated mouse skin carcinogenesis by 1.5 GHz electromagnetic near fields.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenocorticotropic Hormone; Animals; Carcinogens; Carcinoma, Squa | 2001 |
Melatonin, thymic serum factor, and cortisol levels in healthy subjects of different age and patients with skin melanoma.
Topics: Adrenal Cortex; Adult; Age Factors; Female; Humans; Hydrocortisone; Male; Melanoma; Melatonin; Menst | 1986 |
Cutaneous melanoma in miniature swine.
Topics: Animals; Animals, Newborn; Melanoma; Melatonin; Skin Neoplasms; Swine; Swine Diseases | 1968 |
Effect of melatonin on hamster melanoma.
Topics: Animals; Cricetinae; Ethanol; Male; Melanoma; Melatonin; Neoplasm Transplantation; Pineal Gland; Ski | 1973 |