Page last updated: 2024-10-19

melatonin and Cancer of Ovary

melatonin has been researched along with Cancer of Ovary in 36 studies

Research Excerpts

ExcerptRelevanceReference
"Ovarian cancer is the fourth most common cause of cancer deaths among women, and chronic alcoholism may exert co-carcinogenic effects."5.39Characterization of chemically induced ovarian carcinomas in an ethanol-preferring rat model: influence of long-term melatonin treatment. ( Chuffa, LG; Fávaro, WJ; Fioruci-Fontanelli, BA; Martinez, FE; Martinez, M; Mendes, LO; Pinheiro, PF, 2013)
"Findings will provide timely information on the safety, efficacy, and optimal dosing of t-PA to treat moderate/severe COVID-19-induced ARDS, which can be rapidly adapted to a phase III trial (NCT04357730; FDA IND 149634)."4.21 ( Abbasi, S; Abd El-Wahab, A; Abdallah, M; Abebe, G; Aca-Aca, G; Adama, S; Adefegha, SA; Adidigue-Ndiome, R; Adiseshaiah, P; Adrario, E; Aghajanian, C; Agnese, W; Ahmad, A; Ahmad, I; Ahmed, MFE; Akcay, OF; Akinmoladun, AC; Akutagawa, T; Alakavuklar, MA; Álava-Rabasa, S; Albaladejo-Florín, MJ; Alexandra, AJE; Alfawares, R; Alferiev, IS; Alghamdi, HS; Ali, I; Allard, B; Allen, JD; Almada, E; Alobaid, A; Alonso, GL; Alqahtani, YS; Alqarawi, W; Alsaleh, H; Alyami, BA; Amaral, BPD; Amaro, JT; Amin, SAW; Amodio, E; Amoo, ZA; Andia Biraro, I; Angiolella, L; Anheyer, D; Anlay, DZ; Annex, BH; Antonio-Aguirre, B; Apple, S; Arbuznikov, AV; Arinsoy, T; Armstrong, DK; Ash, S; Aslam, M; Asrie, F; Astur, DC; Atzrodt, J; Au, DW; Aucoin, M; Auerbach, EJ; Azarian, S; Ba, D; Bai, Z; Baisch, PRM; Balkissou, AD; Baltzopoulos, V; Banaszewski, M; Banerjee, S; Bao, Y; Baradwan, A; Barandika, JF; Barger, PM; Barion, MRL; Barrett, CD; Basudan, AM; Baur, LE; Baz-Rodríguez, SA; Beamer, P; Beaulant, A; Becker, DF; Beckers, C; Bedel, J; Bedlack, R; Bermúdez de Castro, JM; Berry, JD; Berthier, C; Bhattacharya, D; Biadgo, B; Bianco, G; Bianco, M; Bibi, S; Bigliardi, AP; Billheimer, D; Birnie, DH; Biswas, K; Blair, HC; Bognetti, P; Bolan, PJ; Bolla, JR; Bolze, A; Bonnaillie, P; Borlimi, R; Bórquez, J; Bottari, NB; Boulleys-Nana, JR; Brighetti, G; Brodeur, GM; Budnyak, T; Budnyk, S; Bukirwa, VD; Bulman, DM; Burm, R; Busman-Sahay, K; Butcher, TW; Cai, C; Cai, H; Cai, L; Cairati, M; Calvano, CD; Camacho-Ordóñez, A; Camela, E; Cameron, T; Campbell, BS; Cansian, RL; Cao, Y; Caporale, AS; Carciofi, AC; Cardozo, V; Carè, J; Carlos, AF; Carozza, R; Carroll, CJW; Carsetti, A; Carubelli, V; Casarotta, E; Casas, M; Caselli, G; Castillo-Lora, J; Cataldi, TRI; Cavalcante, ELB; Cavaleiro, A; Cayci, Z; Cebrián-Tarancón, C; Cedrone, E; Cella, D; Cereda, C; Ceretti, A; Ceroni, M; Cha, YH; Chai, X; Chang, EF; Chang, TS; Chanteux, H; Chao, M; Chaplin, BP; Chaturvedi, S; Chaturvedi, V; Chaudhary, DK; Chen, A; Chen, C; Chen, HY; Chen, J; Chen, JJ; Chen, K; Chen, L; Chen, Q; Chen, R; Chen, SY; Chen, TY; Chen, WM; Chen, X; Chen, Y; Cheng, G; Cheng, GJ; Cheng, J; Cheng, YH; Cheon, HG; Chew, KW; Chhoker, S; Chiu, WN; Choi, ES; Choi, MJ; Choi, SD; Chokshi, S; Chorny, M; Chu, KI; Chu, WJ; Church, AL; Cirrincione, A; Clamp, AR; Cleff, MB; Cohen, M; Coleman, RL; Collins, SL; Colombo, N; Conduit, N; Cong, WL; Connelly, MA; Connor, J; Cooley, K; Correa Ramos Leal, I; Cose, S; Costantino, C; Cottrell, M; Cui, L; Cundall, J; Cutaia, C; Cutler, CW; Cuypers, ML; da Silva Júnior, FMR; Dahal, RH; Damiani, E; Damtie, D; Dan-Li, W; Dang, Z; Dasa, SSK; Davin, A; Davis, DR; de Andrade, CM; de Jong, PL; de Oliveira, D; de Paula Dorigam, JC; Dean, A; Deepa, M; Delatour, C; Dell'Aiera, S; Delley, MF; den Boer, RB; Deng, L; Deng, Q; Depner, RM; Derdau, V; Derici, U; DeSantis, AJ; Desmarini, D; Diffo-Sonkoue, L; Divizia, M; Djenabou, A; Djordjevic, JT; Dobrovolskaia, MA; Domizi, R; Donati, A; Dong, Y; Dos Santos, M; Dos Santos, MP; Douglas, RG; Duarte, PF; Dullaart, RPF; Duscha, BD; Edwards, LA; Edwards, TE; Eichenwald, EC; El-Baba, TJ; Elashiry, M; Elashiry, MM; Elashry, SH; Elliott, A; Elsayed, R; Emerson, MS; Emmanuel, YO; Emory, TH; Endale-Mangamba, LM; Enten, GA; Estefanía-Fernández, K; Estes, JD; Estrada-Mena, FJ; Evans, S; Ezra, L; Faria de, RO; Farraj, AK; Favre, C; Feng, B; Feng, J; Feng, L; Feng, W; Feng, X; Feng, Z; Fernandes, CLF; Fernández-Cuadros, ME; Fernie, AR; Ferrari, D; Florindo, PR; Fong, PC; Fontes, EPB; Fontinha, D; Fornari, VJ; Fox, NP; Fu, Q; Fujitaka, Y; Fukuhara, K; Fumeaux, T; Fuqua, C; Fustinoni, S; Gabbanelli, V; Gaikwad, S; Gall, ET; Galli, A; Gancedo, MA; Gandhi, MM; Gao, D; Gao, K; Gao, M; Gao, Q; Gao, X; Gao, Y; Gaponenko, V; Garber, A; Garcia, EM; García-Campos, C; García-Donas, J; García-Pérez, AL; Gasparri, F; Ge, C; Ge, D; Ge, JB; Ge, X; George, I; George, LA; Germani, G; Ghassemi Tabrizi, S; Gibon, Y; Gillent, E; Gillies, RS; Gilmour, MI; Goble, S; Goh, JC; Goiri, F; Goldfinger, LE; Golian, M; Gómez, MA; Gonçalves, J; Góngora-García, OR; Gonul, I; González, MA; Govers, TM; Grant, PC; Gray, EH; Gray, JE; Green, MS; Greenwald, I; Gregory, MJ; Gretzke, D; Griffin-Nolan, RJ; Griffith, DC; Gruppen, EG; Guaita, A; Guan, P; Guan, X; Guerci, P; Guerrero, DT; Guo, M; Guo, P; Guo, R; Guo, X; Gupta, J; Guz, G; Hajizadeh, N; Hamada, H; Haman-Wabi, AB; Han, TT; Hannan, N; Hao, S; Harjola, VP; Harmon, M; Hartmann, MSM; Hartwig, JF; Hasani, M; Hawthorne, WJ; Haykal-Coates, N; Hazari, MS; He, DL; He, P; He, SG; Héau, C; Hebbar Kannur, K; Helvaci, O; Heuberger, DM; Hidalgo, F; Hilty, MP; Hirata, K; Hirsch, A; Hoffman, AM; Hoffmann, JF; Holloway, RW; Holmes, RK; Hong, S; Hongisto, M; Hopf, NB; Hörlein, R; Hoshino, N; Hou, Y; Hoven, NF; Hsieh, YY; Hsu, CT; Hu, CW; Hu, JH; Hu, MY; Hu, Y; Hu, Z; Huang, C; Huang, D; Huang, DQ; Huang, L; Huang, Q; Huang, R; Huang, S; Huang, SC; Huang, W; Huang, Y; Huffman, KM; Hung, CH; Hung, CT; Huurman, R; Hwang, SM; Hyun, S; Ibrahim, AM; Iddi-Faical, A; Immordino, P; Isla, MI; Jacquemond, V; Jacques, T; Jankowska, E; Jansen, JA; Jäntti, T; Jaque-Fernandez, F; Jarvis, GA; Jatt, LP; Jeon, JW; Jeong, SH; Jhunjhunwala, R; Ji, F; Jia, X; Jia, Y; Jian-Bo, Z; Jiang, GD; Jiang, L; Jiang, W; Jiang, WD; Jiang, Z; Jiménez-Hoyos, CA; Jin, S; Jobling, MG; John, CM; John, T; Johnson, CB; Jones, KI; Jones, WS; Joseph, OO; Ju, C; Judeinstein, P; Junges, A; Junnarkar, M; Jurkko, R; Kaleka, CC; Kamath, AV; Kang, X; Kantsadi, AL; Kapoor, M; Karim, Z; Kashuba, ADM; Kassa, E; Kasztura, M; Kataja, A; Katoh, T; Kaufman, JS; Kaupp, M; Kehinde, O; Kehrenberg, C; Kemper, N; Kerr, CW; Khan, AU; Khan, MF; Khan, ZUH; Khojasteh, SC; Kilburn, S; Kim, CG; Kim, DU; Kim, DY; Kim, HJ; Kim, J; Kim, OH; Kim, YH; King, C; Klein, A; Klingler, L; Knapp, AK; Ko, TK; Kodavanti, UP; Kolla, V; Kong, L; Kong, RY; Kong, X; Kore, S; Kortz, U; Korucu, B; Kovacs, A; Krahnert, I; Kraus, WE; Kuang, SY; Kuehn-Hajder, JE; Kurz, M; Kuśtrowski, P; Kwak, YD; Kyttaris, VC; Laga, SM; Laguerre, A; Laloo, A; Langaro, MC; Langham, MC; Lao, X; Larocca, MC; Lassus, J; Lattimer, TA; Lazar, S; Le, MH; Leal, DB; Leal, M; Leary, A; Ledermann, JA; Lee, JF; Lee, MV; Lee, NH; Leeds, CM; Leeds, JS; Lefrandt, JD; Leicht, AS; Leonard, M; Lev, S; Levy, K; Li, B; Li, C; Li, CM; Li, DH; Li, H; Li, J; Li, L; Li, LJ; Li, N; Li, P; Li, T; Li, X; Li, XH; Li, XQ; Li, XX; Li, Y; Li, Z; Li, ZY; Liao, YF; Lin, CC; Lin, MH; Lin, Y; Ling, Y; Links, TP; Lira-Romero, E; Liu, C; Liu, D; Liu, H; Liu, J; Liu, L; Liu, LP; Liu, M; Liu, T; Liu, W; Liu, X; Liu, XH; Liu, Y; Liuwantara, D; Ljumanovic, N; Lobo, L; Lokhande, K; Lopes, A; Lopes, RMRM; López-Gutiérrez, JC; López-Muñoz, MJ; López-Santamaría, M; Lorenzo, C; Lorusso, D; Losito, I; Lu, C; Lu, H; Lu, HZ; Lu, SH; Lu, SN; Lu, Y; Lu, ZY; Luboga, F; Luo, JJ; Luo, KL; Luo, Y; Lutomski, CA; Lv, W; M Piedade, MF; Ma, J; Ma, JQ; Ma, JX; Ma, N; Ma, P; Ma, S; Maciel, M; Madureira, M; Maganaris, C; Maginn, EJ; Mahnashi, MH; Maierhofer, M; Majetschak, M; Malla, TR; Maloney, L; Mann, DL; Mansuri, A; Marelli, E; Margulis, CJ; Marrella, A; Martin, BL; Martín-Francés, L; Martínez de Pinillos, M; Martínez-Navarro, EM; Martinez-Quintanilla Jimenez, D; Martínez-Velasco, A; Martínez-Villaseñor, L; Martinón-Torres, M; Martins, BA; Massongo, M; Mathew, AP; Mathews, D; Matsui, J; Matsumoto, KI; Mau, T; Maves, RC; Mayclin, SJ; Mayer, JM; Maynard, ND; Mayr, T; Mboowa, MG; McEvoy, MP; McIntyre, RC; McKay, JA; McPhail, MJW; McVeigh, AL; Mebazaa, A; Medici, V; Medina, DN; Mehmood, T; Mei-Li, C; Melku, M; Meloncelli, S; Mendes, GC; Mendoza-Velásquez, C; Mercadante, R; Mercado, MI; Merenda, MEZ; Meunier, J; Mi, SL; Michels, M; Mijatovic, V; Mikhailov, V; Milheiro, SA; Miller, DC; Ming, F; Mitsuishi, M; Miyashita, T; Mo, J; Mo, S; Modesto-Mata, M; Moeller, S; Monte, A; Monteiro, L; Montomoli, J; Moore, EE; Moore, HB; Moore, PK; Mor, MK; Moratalla-López, N; Moratilla Lapeña, L; Moreira, R; Moreno, MA; Mörk, AC; Morton, M; Mosier, JM; Mou, LH; Mougharbel, AS; Muccillo-Baisch, AL; Muñoz-Serrano, AJ; Mustafa, B; Nair, GM; Nakanishi, I; Nakanjako, D; Naraparaju, K; Nawani, N; Neffati, R; Neil, EC; Neilipovitz, D; Neira-Borrajo, I; Nelson, MT; Nery, PB; Nese, M; Nguyen, F; Nguyen, MH; Niazy, AA; Nicolaï, J; Nogueira, F; Norbäck, D; Novaretti, JV; O'Donnell, T; O'Dowd, A; O'Malley, DM; Oaknin, A; Ogata, K; Ohkubo, K; Ojha, M; Olaleye, MT; Olawande, B; Olomo, EJ; Ong, EWY; Ono, A; Onwumere, J; Ortiz Bibriesca, DM; Ou, X; Oza, AM; Ozturk, K; Özütemiz, C; Palacio-Pastrana, C; Palaparthi, A; Palevsky, PM; Pan, K; Pantanetti, S; Papachristou, DJ; Pariani, A; Parikh, CR; Parissis, J; Paroul, N; Parry, S; Patel, N; Patel, SM; Patel, VC; Pawar, S; Pefura-Yone, EW; Peixoto Andrade, BCO; Pelepenko, LE; Peña-Lora, D; Peng, S; Pérez-Moro, OS; Perez-Ortiz, AC; Perry, LM; Peter, CM; Phillips, NJ; Phillips, P; Pia Tek, J; Piner, LW; Pinto, EA; Pinto, SN; Piyachaturawat, P; Poka-Mayap, V; Polledri, E; Poloni, TE; Ponessa, G; Poole, ST; Post, AK; Potter, TM; Pressly, BB; Prouty, MG; Prudêncio, M; Pulkki, K; Pupier, C; Qian, H; Qian, ZP; Qiu, Y; Qu, G; Rahimi, S; Rahman, AU; Ramadan, H; Ramanna, S; Ramirez, I; Randolph, GJ; Rasheed, A; Rault, J; Raviprakash, V; Reale, E; Redpath, C; Rema, V; Remucal, CK; Remy, D; Ren, T; Ribeiro, LB; Riboli, G; Richards, J; Rieger, V; Rieusset, J; Riva, A; Rivabella Maknis, T; Robbins, JL; Robinson, CV; Roche-Campo, F; Rodriguez, R; Rodríguez-de-Cía, J; Rollenhagen, JE; Rosen, EP; Rub, D; Rubin, N; Rubin, NT; Ruurda, JP; Saad, O; Sabell, T; Saber, SE; Sabet, M; Sadek, MM; Saejio, A; Salinas, RM; Saliu, IO; Sande, D; Sang, D; Sangenito, LS; Santos, ALSD; Sarmiento Caldas, MC; Sassaroli, S; Sassi, V; Sato, J; Sauaia, A; Saunders, K; Saunders, PR; Savarino, SJ; Scambia, G; Scanlon, N; Schetinger, MR; Schinkel, AFL; Schladweiler, MC; Schofield, CJ; Schuepbach, RA; Schulz, J; Schwartz, N; Scorcella, C; Seeley, J; Seemann, F; Seinige, D; Sengoku, T; Seravalli, J; Sgromo, B; Shaheen, MY; Shan, L; Shanmugam, S; Shao, H; Sharma, S; Shaw, KJ; Shen, BQ; Shen, CH; Shen, P; Shen, S; Shen, Y; Shen, Z; Shi, J; Shi-Li, L; Shimoda, K; Shoji, Y; Shun, C; Silva, MA; Silva-Cardoso, J; Simas, NK; Simirgiotis, MJ; Sincock, SA; Singh, MP; Sionis, A; Siu, J; Sivieri, EM; Sjerps, MJ; Skoczen, SL; Slabon, A; Slette, IJ; Smith, MD; Smith, S; Smith, TG; Snapp, KS; Snow, SJ; Soares, MCF; Soberman, D; Solares, MD; Soliman, I; Song, J; Sorooshian, A; Sorrell, TC; Spinar, J; Staudt, A; Steinhart, C; Stern, ST; Stevens, DM; Stiers, KM; Stimming, U; Su, YG; Subbian, V; Suga, H; Sukhija-Cohen, A; Suksamrarn, A; Suksen, K; Sun, J; Sun, M; Sun, P; Sun, W; Sun, XF; Sun, Y; Sundell, J; Susan, LF; Sutjarit, N; Swamy, KV; Swisher, EM; Sykes, C; Takahashi, JA; Talmor, DS; Tan, B; Tan, ZK; Tang, L; Tang, S; Tanner, JJ; Tanwar, M; Tarazi, Z; Tarvasmäki, T; Tay, FR; Teketel, A; Temitayo, GI; Thersleff, T; Thiessen Philbrook, H; Thompson, LC; Thongon, N; Tian, B; Tian, F; Tian, Q; Timothy, AT; Tingle, MD; Titze, IR; Tolppanen, H; Tong, W; Toyoda, H; Tronconi, L; Tseng, CH; Tu, H; Tu, YJ; Tung, SY; Turpault, S; Tuynman, JB; Uemoto, AT; Ugurlu, M; Ullah, S; Underwood, RS; Ungell, AL; Usandizaga-Elio, I; Vakonakis, I; van Boxel, GI; van den Beucken, JJJP; van der Boom, T; van Slegtenhorst, MA; Vanni, JR; Vaquera, A; Vasconcellos, RS; Velayos, M; Vena, R; Ventura, G; Verso, MG; Vincent, RP; Vitale, F; Vitali, S; Vlek, SL; Vleugels, MPH; Volkmann, N; Vukelic, M; Wagner Mackenzie, B; Wairagala, P; Waller, SB; Wan, J; Wan, MT; Wan, Y; Wang, CC; Wang, H; Wang, J; Wang, JF; Wang, K; Wang, L; Wang, M; Wang, S; Wang, WM; Wang, X; Wang, Y; Wang, YD; Wang, YF; Wang, Z; Wang, ZG; Warriner, K; Weberpals, JI; Weerachayaphorn, J; Wehrli, FW; Wei, J; Wei, KL; Weinheimer, CJ; Weisbord, SD; Wen, S; Wendel Garcia, PD; Williams, JW; Williams, R; Winkler, C; Wirman, AP; Wong, S; Woods, CM; Wu, B; Wu, C; Wu, F; Wu, P; Wu, S; Wu, Y; Wu, YN; Wu, ZH; Wurtzel, JGT; Xia, L; Xia, Z; Xia, ZZ; Xiao, H; Xie, C; Xin, ZM; Xing, Y; Xing, Z; Xu, S; Xu, SB; Xu, T; Xu, X; Xu, Y; Xue, L; Xun, J; Yaffe, MB; Yalew, A; Yamamoto, S; Yan, D; Yan, H; Yan, S; Yan, X; Yang, AD; Yang, E; Yang, H; Yang, J; Yang, JL; Yang, K; Yang, M; Yang, P; Yang, Q; Yang, S; Yang, W; Yang, X; Yang, Y; Yao, JC; Yao, WL; Yao, Y; Yaqub, TB; Ye, J; Ye, W; Yen, CW; Yeter, HH; Yin, C; Yip, V; Yong-Yi, J; Yu, HJ; Yu, MF; Yu, S; Yu, W; Yu, WW; Yu, X; Yuan, P; Yuan, Q; Yue, XY; Zaia, AA; Zakhary, SY; Zalwango, F; Zamalloa, A; Zamparo, P; Zampini, IC; Zani, JL; Zeitoun, R; Zeng, N; Zenteno, JC; Zepeda-Palacio, C; Zhai, C; Zhang, B; Zhang, G; Zhang, J; Zhang, K; Zhang, Q; Zhang, R; Zhang, T; Zhang, X; Zhang, Y; Zhang, YY; Zhao, B; Zhao, D; Zhao, G; Zhao, H; Zhao, Q; Zhao, R; Zhao, S; Zhao, T; Zhao, X; Zhao, XA; Zhao, Y; Zhao, Z; Zheng, Z; Zhi-Min, G; Zhou, CL; Zhou, HD; Zhou, J; Zhou, W; Zhou, XQ; Zhou, Z; Zhu, C; Zhu, H; Zhu, L; Zhu, Y; Zitzmann, N; Zou, L; Zou, Y, 2022)
"An interaction between cellular estrogen response and melatonin signaling mediated by G-protein coupled receptors is present in breast cancer cells."3.73Antiestrogens modulate MT1 melatonin receptor expression in breast and ovarian cancer cell lines. ( Haldar, C; Ortmann, O; Treeck, O, 2006)
"The pineal hormone melatonin has been reported to have in vitro antiproliferative effects on estrogen receptor-positive human breast cancer cell lines at concentrations near to plasma physiological concentrations (1 x 10(-11) to 1 x 10(-9) M)."3.70Effects of melatonin on proliferation of cancer cell lines. ( Dimitriadis, KA; Geromichalos, GD; Kortsaris, AH; Kouretas, D; Papazisis, KT; Sivridis, E; Tsekreli, OK, 1998)
"The melatonin hypothesis states that excess exposure to environmental light may contribute to breast cancer risks via impaired pineal secretion of melatonin."3.70Does winter darkness in the Artic protect against cancer? The melatonin hypothesis revisited. ( Erren, TC; Piekarski, C, 1999)
" Except for melatonin, all neuroendocrine hormones used in this study inhibited proliferation of KF cells derived from human serous cystadenocarcinoma of the ovary in a dose-dependent manner."3.67Inhibition of human ovarian cancer cell proliferation in vitro by neuroendocrine hormones. ( Iwano, I; Kato, K; Kikuchi, Y; Kita, T; Miyauchi, M, 1989)
"Ovarian cancer is one of the most common causes of morbidity related to gynecologic malignancies."2.61Melatonin is a potential inhibitor of ovarian cancer: molecular aspects. ( Asemi, Z; Reiter, RJ; Shafabakhsh, R; Zare, H, 2019)
"Melatonin is an indoleamine secreted by the pineal gland during darkness and has shown antitumor activity in both in vitro and in vivo experiments."1.72The proteomic landscape of ovarian cancer cells in response to melatonin. ( Cesário, RC; Cucielo, MS; de Almeida Chuffa, LG; de Campos Zuccari, DAP; Delazari Dos Santos, L; Gaiotte, LB; Reiter, RJ; Seiva, FRF; Silveira, HS, 2022)
"Sirtuins, enzymes involved in metastasis formation, have also been detected."1.72The role of selected molecular factors in ovarian cancer metastasis. ( Fechner, J; Markowska, A; Markowska, J; Sawicki, W; Zurawski, J, 2022)
"Melatonin-treated animals showed a significant reduction in OC size and microvessel density."1.46Melatonin Reduces Angiogenesis in Serous Papillary Ovarian Carcinoma of Ethanol-Preferring Rats. ( Camargo, IC; Chuffa, LG; Domeniconi, RF; Lupi Júnior, LA; Martinez, FE; Martinez, M; Pinheiro, PF; Reiter, RJ; Zonta, YR, 2017)
"Melatonin (Mel) is an indoleamine displaying several anti-cancer properties and has been reported to modulate apoptosis signaling in multiple tumor subtypes."1.43Apoptosis is triggered by melatonin in an in vivo model of ovarian carcinoma. ( Alves, MS; Camargo, IC; Chuffa, LG; Domeniconi, RF; Júnior, LA; Martinez, FE; Martinez, M; Pinheiro, PF, 2016)
"Melatonin has also been found to have anti-tumor properties."1.43Melatonin Suppresses the Growth of Ovarian Cancer Cell Lines (OVCAR-429 and PA-1) and Potentiates the Effect of G1 Arrest by Targeting CDKs. ( Chang, CC; Chen, YT; Hsu, YC; Lai, CS; Shen, CJ, 2016)
"Melatonin (mel) acts as an anti-inflammatory factor and has been reported to modulate TLRs in some aggressive tumor cell types."1.42Melatonin attenuates the TLR4-mediated inflammatory response through MyD88- and TRIF-dependent signaling pathways in an in vivo model of ovarian cancer. ( Chuffa, LG; Delazari Dos Santos, L; Domeniconi, RF; Fávaro, WJ; Ferreira Seiva, FR; Fioruci-Fontanelli, BA; Martinez, FE; Martinez, M; Mendes, LO; Pinheiro, PF, 2015)
"Melatonin has anti-carcinogenic properties, including modulation of estradiol production, cell cycle regulation, and promotion of apoptosis."1.42Urinary melatonin and risk of ovarian cancer. ( Hankinson, SE; Mills, L; Poole, EM; Schernhammer, E; Tworoger, SS, 2015)
"Ovarian cancer is the fourth most common cause of cancer deaths among women, and chronic alcoholism may exert co-carcinogenic effects."1.39Characterization of chemically induced ovarian carcinomas in an ethanol-preferring rat model: influence of long-term melatonin treatment. ( Chuffa, LG; Fávaro, WJ; Fioruci-Fontanelli, BA; Martinez, FE; Martinez, M; Mendes, LO; Pinheiro, PF, 2013)
"After surgical ablation of the breast tumors, serum's ability to increase MCF-7 cell proliferation decreased significantly."1.31Influence of serum from healthy or breast tumor-bearing women on the growth of MCF-7 human breast cancer cells. ( Alvarez, A; Bartsch, C; Bartsch, H; Cos, S; Mediavilla, MD; Sanchez-Barcelo, EJ, 2000)
"Thus, melatonin may improve ovarian cancer chemotherapy."1.31Effects of melatonin on the proliferation and cis-diamminedichloroplatinum (CDDP) sensitivity of cultured human ovarian cancer cells. ( Futagami, M; Saito, Y; Sakamoto, T; Sato, S; Yokoyama, Y, 2001)
"Melatonin did not inhibit estradiol-stimulated proliferation under this protocol."1.30Melatonin does not inhibit estradiol-stimulated proliferation in MCF-7 and BG-1 cells. ( Baldwin, WS; Barrett, JC; Risinger, JI; Travlos, GS, 1998)

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19903 (8.33)18.7374
1990's4 (11.11)18.2507
2000's7 (19.44)29.6817
2010's15 (41.67)24.3611
2020's7 (19.44)2.80

Authors

AuthorsStudies
Cesário, RC2
Gaiotte, LB2
Cucielo, MS3
Silveira, HS3
Delazari Dos Santos, L2
de Campos Zuccari, DAP2
Seiva, FRF3
Reiter, RJ6
de Almeida Chuffa, LG3
Dos Santos, SAA1
Markowska, A1
Sawicki, W1
Zurawski, J1
Fechner, J1
Markowska, J1
Baghal-Sadriforoush, S1
Bagheri, M1
Abdi Rad, I1
Sotoodehnejadnematalahi, F1
Abir, R2
Stav, D1
Taieb, Y1
Gabbay-Benziv, R1
Kirshner, M1
Ben-Haroush, A2
Freud, E2
Ash, S2
Yaniv, I1
Herman-Edelstein, M1
Fisch, B2
Shufaro, Y1
Bu, S1
Wang, Q1
Sun, J2
Li, X5
Gu, T1
Lai, D1
Nese, M1
Riboli, G1
Brighetti, G1
Sassi, V1
Camela, E1
Caselli, G1
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Zhang, K1
Wang, M1
Xia, Z1
Gao, D1
Balkissou, AD1
Poka-Mayap, V1
Massongo, M1
Djenabou, A1
Endale-Mangamba, LM1
Olomo, EJ1
Boulleys-Nana, JR1
Diffo-Sonkoue, L1
Adidigue-Ndiome, R1
Alexandra, AJE1
Haman-Wabi, AB1
Adama, S1
Iddi-Faical, A1
Pefura-Yone, EW1
Zhao, Q1
Tong, W1
Ge, C1
Zhao, D1
Norbäck, D1
Li, B1
Zhao, Z1
Huang, C1
Zhang, X1
Qian, H1
Yang, X1
Sun, Y1
Sundell, J1
Deng, Q1
Kim, HJ1
Jeon, JW1
Hwang, SM1
Chu, KI1
Cha, YH1
Kwak, YD1
Choi, SD1
Aslam, M1
Kim, CG1
Zhou, J1
Yang, E1
Yang, W1
Zonta, YR1
Martinez, M5
Camargo, IC2
Domeniconi, RF4
Lupi Júnior, LA2
Pinheiro, PF5
Martinez, FE5
Chuffa, LG5
Chuffa, LGA1
Lupi, LA2
Akbarzadeh, M3
Movassaghpour, AA2
Ghanbari, H1
Kheirandish, M1
Fathi Maroufi, N1
Rahbarghazi, R3
Nouri, M3
Samadi, N3
Zare, H1
Shafabakhsh, R1
Asemi, Z1
Fioruci-Fontanelli, BA2
Mendes, LO2
Fávaro, WJ2
Ferreira Seiva, FR1
Poole, EM1
Schernhammer, E1
Mills, L1
Hankinson, SE1
Tworoger, SS1
Alves, MS1
Júnior, LA1
Shen, CJ1
Chang, CC1
Chen, YT1
Lai, CS1
Hsu, YC1
Banekohal, MV1
Cheraghi, O1
Tajalli, H1
Movassaghpour, A1
Soltani, S1
Cheraghi, H1
Feizy, N1
Montazersaheb, S1
Seiva, FR1
Dos Santos, LD1
Nabat, E1
Shanehbandi, D1
Faramarzian Azimi Maragheh, B1
Matluobi, D1
Barazvan, B1
Kazemi, M1
Bilski, B1
Kim, JH1
Jeong, SJ1
Kim, B1
Yun, SM1
Choi, DY1
Kim, SH1
Friedman, O1
Orvieto, R1
Felz, C1
Treeck, O1
Haldar, C1
Ortmann, O1
Halberg, F1
Cornélissen, G1
Ulmer, W1
Blank, M1
Hrushesky, W1
Wood, P1
Singh, RK1
Baldwin, WS1
Travlos, GS1
Risinger, JI1
Barrett, JC2
Papazisis, KT1
Kouretas, D1
Geromichalos, GD1
Sivridis, E1
Tsekreli, OK1
Dimitriadis, KA1
Kortsaris, AH1
Petranka, J1
Baldwin, W1
Biermann, J1
Jayadev, S1
Murphy, E1
Erren, TC1
Piekarski, C1
Cos, S1
Alvarez, A1
Mediavilla, MD1
Bartsch, C2
Bartsch, H2
Sanchez-Barcelo, EJ1
Meredith, S1
Jackson, K1
Dudenhoeffer, G1
Graham, L1
Epple, J1
Buchberger, A1
Franz, H1
Maidonis, I1
Mecke, D1
Bayer, E1
Futagami, M1
Sato, S1
Sakamoto, T1
Yokoyama, Y1
Saito, Y1
Lapin, V1
Kikuchi, Y2
Kita, T2
Miyauchi, M2
Iwano, I2
Kato, K2
Oomori, K1
Kizawa, I1

Reviews

7 reviews available for melatonin and Cancer of Ovary

ArticleYear
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
Melatonin as a promising agent to treat ovarian cancer: molecular mechanisms.
    Carcinogenesis, 2017, 10-01, Volume: 38, Issue:10

    Topics: Antineoplastic Agents; Apoptosis; Female; Humans; Melatonin; Ovarian Neoplasms; Signal Transduction

2017
Mitochondrial functions and melatonin: a tour of the reproductive cancers.
    Cellular and molecular life sciences : CMLS, 2019, Volume: 76, Issue:5

    Topics: Animals; Breast Neoplasms; Endometrial Neoplasms; Female; Genital Neoplasms, Female; Humans; Male; M

2019
Melatonin is a potential inhibitor of ovarian cancer: molecular aspects.
    Journal of ovarian research, 2019, Mar-26, Volume: 12, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Female; Humans; Melatonin; M

2019
[Shift and night work--is it a cancer risk factor?].
    Medycyna pracy, 2005, Volume: 56, Issue:2

    Topics: Breast Neoplasms; Causality; Chronobiology Disorders; Circadian Rhythm; Colorectal Neoplasms; Female

2005
Cancer chronomics III. Chronomics for cancer, aging, melatonin and experimental therapeutics researchers.
    Journal of experimental therapeutics & oncology, 2006, Volume: 6, Issue:1

    Topics: Aging; Animals; Antineoplastic Agents; Chronotherapy; Circadian Rhythm; Female; Humans; Lentinan; Ma

2006
Pineal gland and malignancy.
    Osterreichische Zeitschrift fur Onkologie. Austrian journal of oncology, 1976, Sep-13, Volume: 3, Issue:3

    Topics: Age Factors; Animals; Breast Neoplasms; Carcinogens; Carcinoma; Female; Gonadotropins; Humans; Lymph

1976

Trials

1 trial available for melatonin and Cancer of Ovary

ArticleYear
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022

Other Studies

29 other studies available for melatonin and Cancer of Ovary

ArticleYear
The proteomic landscape of ovarian cancer cells in response to melatonin.
    Life sciences, 2022, Apr-01, Volume: 294

    Topics: Antioxidants; Apoptosis; Biomarkers, Tumor; Case-Control Studies; Cell Proliferation; Female; Gene E

2022
Melatonin Reverses the Warburg-Type Metabolism and Reduces Mitochondrial Membrane Potential of Ovarian Cancer Cells Independent of MT1 Receptor Activation.
    Molecules (Basel, Switzerland), 2022, Jul-07, Volume: 27, Issue:14

    Topics: Carcinoma, Ovarian Epithelial; Female; Humans; Melatonin; Membrane Potential, Mitochondrial; Ovarian

2022
The role of selected molecular factors in ovarian cancer metastasis.
    Ginekologia polska, 2022, Volume: 93, Issue:8

    Topics: Ascites; Carcinoma, Ovarian Epithelial; Cell Movement; Female; Gene Expression Regulation, Neoplasti

2022
Melatonin Sensitizes OVCAR-3 Cells to Cisplatin through Suppression of PI3K/Akt Pathway.
    Cellular and molecular biology (Noisy-le-Grand, France), 2022, Apr-30, Volume: 68, Issue:4

    Topics: Apoptosis; Cell Line, Tumor; Cisplatin; Female; Humans; Melatonin; Ovarian Neoplasms; Phosphatidylin

2022
Novel extra cellular-like matrices to improve human ovarian grafting.
    Journal of assisted reproduction and genetics, 2020, Volume: 37, Issue:9

    Topics: Animals; Apoptosis; Cancer Survivors; Female; Gene Expression Regulation, Developmental; Humans; Ki-

2020
Melatonin suppresses chronic restraint stress-mediated metastasis of epithelial ovarian cancer via NE/AKT/β-catenin/SLUG axis.
    Cell death & disease, 2020, 08-18, Volume: 11, Issue:8

    Topics: Animals; beta Catenin; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Movement; Epithelial Ce

2020
Melatonin Reduces Angiogenesis in Serous Papillary Ovarian Carcinoma of Ethanol-Preferring Rats.
    International journal of molecular sciences, 2017, Apr-11, Volume: 18, Issue:4

    Topics: Alcohol Drinking; Animals; Antioxidants; Blotting, Western; Cystadenocarcinoma, Papillary; Cystadeno

2017
The potential therapeutic effect of melatonin on human ovarian cancer by inhibition of invasion and migration of cancer stem cells.
    Scientific reports, 2017, 12-06, Volume: 7, Issue:1

    Topics: Cadherins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Down-Regulation; Epithelial-Mesenchy

2017
Characterization of chemically induced ovarian carcinomas in an ethanol-preferring rat model: influence of long-term melatonin treatment.
    PloS one, 2013, Volume: 8, Issue:12

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Estrous Cycle; Ethanol; Female; Melatonin; Ova

2013
Melatonin attenuates the TLR4-mediated inflammatory response through MyD88- and TRIF-dependent signaling pathways in an in vivo model of ovarian cancer.
    BMC cancer, 2015, Feb-06, Volume: 15

    Topics: Adaptor Proteins, Vesicular Transport; Animals; Cytokines; Disease Models, Animal; Female; Gene Expr

2015
Urinary melatonin and risk of ovarian cancer.
    Cancer causes & control : CCC, 2015, Volume: 26, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Circadian Rhythm; Female; Humans; Logistic Mod

2015
Apoptosis is triggered by melatonin in an in vivo model of ovarian carcinoma.
    Endocrine-related cancer, 2016, Volume: 23, Issue:2

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Disease Models, Animal; Down-Regulation;

2016
Melatonin Suppresses the Growth of Ovarian Cancer Cell Lines (OVCAR-429 and PA-1) and Potentiates the Effect of G1 Arrest by Targeting CDKs.
    International journal of molecular sciences, 2016, Jan-29, Volume: 17, Issue:2

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase 2; Cyclin-Depen

2016
Effects of combination of melatonin and laser irradiation on ovarian cancer cells and endothelial lineage viability.
    Lasers in medical science, 2016, Volume: 31, Issue:8

    Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Female; HSP70 Heat-Shock Proteins; Human Umbilical Vein

2016
Quantitative Proteomic Profiling Reveals That Diverse Metabolic Pathways Are Influenced by Melatonin in an in Vivo Model of Ovarian Carcinoma.
    Journal of proteome research, 2016, 10-07, Volume: 15, Issue:10

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Disease Models, Animal; Female; Melatonin; Metabolic Netw

2016
The impact of different extracellular matrices on melatonin effect in proliferation and stemness properties of ovarian cancer cells.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 87

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Extracellular Matrix; Female; Humans;

2017
Melatonin synergistically enhances cisplatin-induced apoptosis via the dephosphorylation of ERK/p90 ribosomal S6 kinase/heat shock protein 27 in SK-OV-3 cells.
    Journal of pineal research, 2012, Volume: 52, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Survival; Cisplatin; Dru

2012
Possible improvements in human ovarian grafting by various host and graft treatments.
    Human reproduction (Oxford, England), 2012, Volume: 27, Issue:2

    Topics: Adhesives; Adolescent; Adult; Animals; Apoptosis; Child; Cryopreservation; Female; Fertility Agents,

2012
Antiestrogens modulate MT1 melatonin receptor expression in breast and ovarian cancer cell lines.
    Oncology reports, 2006, Volume: 15, Issue:1

    Topics: Breast Neoplasms; Cell Line, Tumor; Estradiol; Estrogen Receptor Modulators; Female; Fulvestrant; Hu

2006
Melatonin does not inhibit estradiol-stimulated proliferation in MCF-7 and BG-1 cells.
    Carcinogenesis, 1998, Volume: 19, Issue:11

    Topics: Animals; Breast Neoplasms; Cell Cycle; Cell Division; Estradiol; Female; Humans; Melatonin; Mice; Mi

1998
Effects of melatonin on proliferation of cancer cell lines.
    Journal of pineal research, 1998, Volume: 25, Issue:4

    Topics: Breast Neoplasms; Buthionine Sulfoximine; Cell Division; Cell Survival; Colonic Neoplasms; DNA Repli

1998
The oncostatic action of melatonin in an ovarian carcinoma cell line.
    Journal of pineal research, 1999, Volume: 26, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Calcium; Cell Count; Cell Cycle; Cell Division; DN

1999
Does winter darkness in the Artic protect against cancer? The melatonin hypothesis revisited.
    Medical hypotheses, 1999, Volume: 53, Issue:1

    Topics: Alaska; Arctic Regions; Breast Neoplasms; Canada; Darkness; Female; Greenland; Humans; Male; Melaton

1999
Influence of serum from healthy or breast tumor-bearing women on the growth of MCF-7 human breast cancer cells.
    International journal of molecular medicine, 2000, Volume: 5, Issue:6

    Topics: Adenocarcinoma, Papillary; Breast Neoplasms; Cell Division; Culture Media; Endometrial Neoplasms; Es

2000
Long-term supplementation with melatonin delays reproductive senescence in rats, without an effect on number of primordial follicles.
    Experimental gerontology, 2000, Volume: 35, Issue:3

    Topics: Aging; Animals; Drug Administration Schedule; Female; Male; Melatonin; Ovarian Follicle; Ovarian Neo

2000
Effect of melatonin and pineal extracts on human ovarian and mammary tumor cells in a chemosensitivity assay.
    Life sciences, 2000, Nov-03, Volume: 67, Issue:24

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents; Breast Neoplasms; Cisplatin; Cycloph

2000
Effects of melatonin on the proliferation and cis-diamminedichloroplatinum (CDDP) sensitivity of cultured human ovarian cancer cells.
    Gynecologic oncology, 2001, Volume: 82, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cisplatin; Dose-Response Relationship

2001
Inhibition of human ovarian cancer cell proliferation in vitro by neuroendocrine hormones.
    Gynecologic oncology, 1989, Volume: 32, Issue:1

    Topics: beta-Endorphin; Cell Division; Cystadenocarcinoma; DNA, Neoplasm; Dose-Response Relationship, Drug;

1989
Inhibitory effects of neuroendocrine hormones on human ovarian cancer cell proliferation in vitro.
    Nihon Sanka Fujinka Gakkai zasshi, 1987, Volume: 39, Issue:9

    Topics: Cell Division; Cell Line; Endorphins; Enkephalin, Methionine; Female; Humans; Melatonin; Naloxone; O

1987