melatonin has been researched along with Cancer of Colon in 43 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "On the basis of the demonstrated existence of immunoneuroendocrine interactions and on the previously observed synergistic action between the pineal hormone melatonin (MLT) and interleukin-2 (IL-2), we have designed a neuroimmunotherapeutic combination consisting of low-dose IL-2 and MLT in the treatment of advanced solid neoplasms." | 7.68 | Neuroimmunotherapy of advanced solid neoplasms with single evening subcutaneous injection of low-dose interleukin-2 and melatonin: preliminary results. ( Ardizzoia, A; Barni, S; Brivio, F; Conti, A; Lissoni, P; Maestroni, GJ; Rovelli, F; Tancini, G, 1993) |
| "Plasma melatonin was determined in samples of patients with colorectal carcinoma and in controls using an iodinated radioimmunoassay." | 7.67 | Plasma melatonin levels in patients suffering from colorectal carcinoma. ( Khoory, R; Stemme, D, 1988) |
| "Colon carcinogenesis is long known to be associated with ulcerative colitis (UC), a chronic gastrointestinal disorder." | 5.43 | Melatonin modulated autophagy and Nrf2 signaling pathways in mice with colitis-associated colon carcinogenesis. ( Jena, GB; Kumar, V; Tikoo, KB; Trivedi, PP, 2016) |
| "Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy." | 4.40 | Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023) |
| "The pineal hormone melatonin has been reported to have in vitro antiproliferative effects on estrogen receptor-positive human breast cancer cell lines at concentrations near to plasma physiological concentrations (1 x 10(-11) to 1 x 10(-9) M)." | 3.70 | Effects of melatonin on proliferation of cancer cell lines. ( Dimitriadis, KA; Geromichalos, GD; Kortsaris, AH; Kouretas, D; Papazisis, KT; Sivridis, E; Tsekreli, OK, 1998) |
| " injections of 1,2-dimethylhydrazine (DMH) at a single dose of 21 mg/kg of body weight." | 3.69 | Melatonin and colon carcinogenesis: I. Inhibitory effect of melatonin on development of intestinal tumors induced by 1,2-dimethylhydrazine in rats. ( Anisimov, VN; Popovich, IG; Zabezhinski, MA, 1997) |
| "On the basis of the demonstrated existence of immunoneuroendocrine interactions and on the previously observed synergistic action between the pineal hormone melatonin (MLT) and interleukin-2 (IL-2), we have designed a neuroimmunotherapeutic combination consisting of low-dose IL-2 and MLT in the treatment of advanced solid neoplasms." | 3.68 | Neuroimmunotherapy of advanced solid neoplasms with single evening subcutaneous injection of low-dose interleukin-2 and melatonin: preliminary results. ( Ardizzoia, A; Barni, S; Brivio, F; Conti, A; Lissoni, P; Maestroni, GJ; Rovelli, F; Tancini, G, 1993) |
| "Plasma melatonin was determined in samples of patients with colorectal carcinoma and in controls using an iodinated radioimmunoassay." | 3.67 | Plasma melatonin levels in patients suffering from colorectal carcinoma. ( Khoory, R; Stemme, D, 1988) |
| "Melatonin has been shown as a specific antioxidant reducing oxidative damage in both lipid and aqueous cell environments." | 2.47 | New paradigms in chronic intestinal inflammation and colon cancer: role of melatonin. ( García-Mauriño, S; Illanes, M; Motilva, V; Talero, E, 2011) |
| "Melatonin is a hormone synthesized in the pineal gland and is responsible for circadian rhythm." | 1.91 | Combination of Irinotecan and Melatonin with the Natural Compounds Wogonin and Celastrol for Colon Cancer Treatment. ( Barg, E; Bęben, D; Emhemmed, F; Frąszczak, J; Gębczak, K; Moreira, H; Muller, CD; Nowak, P; Radajewska, A; Siwiela, O; Szyjka, A, 2023) |
| "Colon cancer is one of the most important causes of death in the entire world." | 1.72 | Melatonin Enhances Anti-tumoral Effects of Menadione on Colon Cancer Cells. ( Collin, A; Kohan, R; Picotto, G; Tolosa de Talamoni, N, 2022) |
| "CSCs, spheroids derived from colon cancer cells, are responsible for metastasis, drug resistance, and disease recurrence." | 1.72 | Melatonin and andrographolide synergize to inhibit the colospheroid phenotype by targeting Wnt/beta-catenin signaling. ( Ahmed, H; Banerjee, A; Giri, B; Hassan, MS; Kristian, T; Lohr, C; Reiter, RJ; Sharda, N; Singh, D; Sokolov, D; Tarasiewicz, A; von Holzen, U; Waddell, J, 2022) |
| "Colon carcinogenesis is long known to be associated with ulcerative colitis (UC), a chronic gastrointestinal disorder." | 1.43 | Melatonin modulated autophagy and Nrf2 signaling pathways in mice with colitis-associated colon carcinogenesis. ( Jena, GB; Kumar, V; Tikoo, KB; Trivedi, PP, 2016) |
| "Colon cancer is among the most dangerous tumors affecting humankind." | 1.42 | Pineal gland function is required for colon antipreneoplastic effects of physical exercise in rats. ( de Paula Garcia, W; Fernandes, CR; Frajacomo, FT; Garcia, SB; Kannen, V, 2015) |
| "Melatonin could inhibit the proliferation and migration of RKO cells, and further experiments confirmed that p38 MAPK plays an important role in regulating melatonin-induced migration inhibition through down-regulating the expression and activity of MLCK." | 1.42 | Melatonin inhibits the Migration of Colon Cancer RKO cells by Down-regulating Myosin Light Chain Kinase Expression through Cross-talk with p38 MAPK. ( Gui, SY; Hu, RL; Wang, Y; Wei, X; Yang, XP; Zhang, SM; Zhou, Q; Zhu, HQ; Zou, DB; Zuo, L, 2015) |
| "Melatonin is an indoleamine that is synthesised from tryptophan under the control of the enzymes arylalkylamine N-acetyltransferase (AA-NAT) and acetylserotonin methyltransferase (ASMT)." | 1.40 | Melatonin reduces endothelin-1 expression and secretion in colon cancer cells through the inactivation of FoxO-1 and NF-κβ. ( Casado, J; Gila, A; González-Puga, C; Jiménez Ruiz, SM; León, J; Muñoz de Rueda, P; Pavón, EJ; Reiter, RJ; Rejón, JD; Ruiz-Extremera, A; Salmerón, J; Zurita, MS, 2014) |
| "Melatonin is an indoleamine compound produced in the pineal gland and also a plant-derived product." | 1.39 | Melatonin potentiates the antiproliferative and pro-apoptotic effects of ursolic acid in colon cancer cells by modulating multiple signaling pathways. ( Chen, W; Deng, W; Fu, L; Guo, W; Huang, W; Shi, D; Tian, Y; Tong, B; Wang, J; Xiao, X; Yu, W, 2013) |
| "Melatonin caused an increase in cytosolic lactate levels that most likely allows the flavone-induced activation of the mitochondrial pyruvate/lactate importer to deliver more substrates to mitochondrial respiration." | 1.33 | Melatonin potentiates flavone-induced apoptosis in human colon cancer cells by increasing the level of glycolytic end products. ( Daniel, H; Nickel, A; Wenzel, U, 2005) |
| "Melatonin was also shown to inhibit carcinogenesis in the small intestine." | 1.29 | [Effect of melatonin on 1,2-dimethylhydrazine-induced intestinal tumors in rats]. ( Anisimov, VN; Muratov, EI; Popovich, IG, 1996) |
| "Breast cancer, lung carcinoma, and colorectum cancer were the three neoplasms detected in the patients investigated." | 1.27 | A study on the relationship between the pineal gland and the opioid system in patients with cancer. Preliminary considerations. ( Barni, S; Cattaneo, G; Crispino, S; Esposti, D; Esposti, G; Ferri, L; Lissoni, P; Paolorossi, F; Rovelli, F; Tancini, G, 1988) |
| "Melatonin serum levels were measured by radioimmunoassay before and 28 days after each cycle of chemotherapy." | 1.27 | Melatonin increase as predictor for tumor objective response to chemotherapy in advanced cancer patients. ( Barni, S; Cattaneo, G; Crispino, S; Fraschini, F; Lissoni, P; Paolorossi, F; Rovelli, F; Tancini, G, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (9.30) | 18.7374 |
| 1990's | 8 (18.60) | 18.2507 |
| 2000's | 9 (20.93) | 29.6817 |
| 2010's | 16 (37.21) | 24.3611 |
| 2020's | 6 (13.95) | 2.80 |
| Authors | Studies |
|---|---|
| Collin, A | 1 |
| Kohan, R | 1 |
| Tolosa de Talamoni, N | 1 |
| Picotto, G | 1 |
| Sokolov, D | 2 |
| Sharda, N | 2 |
| Giri, B | 1 |
| Hassan, MS | 1 |
| Singh, D | 2 |
| Tarasiewicz, A | 1 |
| Lohr, C | 1 |
| von Holzen, U | 1 |
| Kristian, T | 1 |
| Waddell, J | 1 |
| Reiter, RJ | 3 |
| Ahmed, H | 1 |
| Banerjee, A | 2 |
| Mafi, A | 1 |
| Rezaee, M | 1 |
| Hedayati, N | 1 |
| Hogan, SD | 1 |
| Aarabi, MH | 1 |
| Asemi, Z | 1 |
| Radajewska, A | 1 |
| Moreira, H | 1 |
| Bęben, D | 1 |
| Siwiela, O | 1 |
| Szyjka, A | 1 |
| Gębczak, K | 1 |
| Nowak, P | 1 |
| Frąszczak, J | 1 |
| Emhemmed, F | 1 |
| Muller, CD | 1 |
| Barg, E | 1 |
| Banerjee, V | 1 |
| Huse, J | 1 |
| Czinn, SJ | 1 |
| Blanchard, TG | 1 |
| Fic, M | 1 |
| Gomulkiewicz, A | 1 |
| Grzegrzolka, J | 1 |
| Podhorska-Okolow, M | 1 |
| Zabel, M | 1 |
| Dziegiel, P | 1 |
| Jablonska, K | 1 |
| Liu, Z | 1 |
| Zou, D | 1 |
| Yang, X | 1 |
| Xue, X | 1 |
| Zuo, L | 2 |
| Zhou, Q | 2 |
| Hu, R | 1 |
| Wang, Y | 2 |
| Lee, JH | 1 |
| Yun, CW | 1 |
| Han, YS | 1 |
| Kim, S | 1 |
| Jeong, D | 1 |
| Kwon, HY | 1 |
| Kim, H | 1 |
| Baek, MJ | 1 |
| Lee, SH | 1 |
| Abadi, SHMH | 1 |
| Shirazi, A | 1 |
| Alizadeh, AM | 1 |
| Changizi, V | 1 |
| Najafi, M | 1 |
| Khalighfard, S | 1 |
| Nosrati, H | 1 |
| León, J | 1 |
| Casado, J | 1 |
| Jiménez Ruiz, SM | 1 |
| Zurita, MS | 1 |
| González-Puga, C | 2 |
| Rejón, JD | 1 |
| Gila, A | 1 |
| Muñoz de Rueda, P | 1 |
| Pavón, EJ | 1 |
| Ruiz-Extremera, A | 1 |
| Salmerón, J | 1 |
| Frajacomo, FT | 2 |
| de Paula Garcia, W | 1 |
| Fernandes, CR | 1 |
| Garcia, SB | 2 |
| Kannen, V | 2 |
| Trivedi, PP | 1 |
| Jena, GB | 1 |
| Tikoo, KB | 1 |
| Kumar, V | 1 |
| Zou, DB | 1 |
| Wei, X | 1 |
| Hu, RL | 1 |
| Yang, XP | 1 |
| Zhang, SM | 1 |
| Zhu, HQ | 1 |
| Gui, SY | 1 |
| Mori, F | 1 |
| Ferraiuolo, M | 1 |
| Santoro, R | 1 |
| Sacconi, A | 1 |
| Goeman, F | 1 |
| Pallocca, M | 1 |
| Pulito, C | 1 |
| Korita, E | 1 |
| Fanciulli, M | 1 |
| Muti, P | 1 |
| Blandino, G | 1 |
| Strano, S | 1 |
| Pliss, MM | 1 |
| Sedov, VM | 1 |
| Fishman, MB | 1 |
| Gao, Y | 1 |
| Xiao, X | 2 |
| Zhang, C | 1 |
| Yu, W | 2 |
| Guo, W | 2 |
| Zhang, Z | 1 |
| Li, Z | 1 |
| Feng, X | 1 |
| Hao, J | 1 |
| Zhang, K | 1 |
| Xiao, B | 1 |
| Chen, M | 1 |
| Huang, W | 2 |
| Xiong, S | 1 |
| Wu, X | 1 |
| Deng, W | 2 |
| Panchenko, AV | 1 |
| Petrishchev, NN | 1 |
| Kvetnoĭ, IM | 2 |
| Anisimov, VN | 6 |
| Tanaka, T | 2 |
| Yasui, Y | 1 |
| Tanaka, M | 1 |
| Oyama, T | 1 |
| Rahman, KM | 1 |
| Winczyk, K | 4 |
| Fuss-Chmielewska, J | 1 |
| Lawnicka, H | 2 |
| Pawlikowski, M | 4 |
| Karasek, M | 4 |
| Park, SY | 1 |
| Jang, WJ | 1 |
| Yi, EY | 1 |
| Jang, JY | 1 |
| Jung, Y | 1 |
| Jeong, JW | 1 |
| Kim, YJ | 1 |
| Rakhimova, OIu | 1 |
| Paĭzullaeva, ZK | 1 |
| Aleksandrov, VB | 1 |
| Marini, T | 1 |
| Zanette, DL | 1 |
| Silva, GE | 1 |
| Silva, WA | 1 |
| Motilva, V | 1 |
| García-Mauriño, S | 1 |
| Talero, E | 1 |
| Illanes, M | 1 |
| Wang, J | 1 |
| Chen, W | 1 |
| Tian, Y | 1 |
| Fu, L | 1 |
| Shi, D | 1 |
| Tong, B | 1 |
| Wenzel, U | 1 |
| Nickel, A | 1 |
| Daniel, H | 1 |
| Vinogradova, IA | 1 |
| García-Navarro, A | 1 |
| Escames, G | 1 |
| López, LC | 1 |
| López, A | 1 |
| López-Cantarero, M | 1 |
| Camacho, E | 1 |
| Espinosa, A | 1 |
| Gallo, MA | 1 |
| Acuña-Castroviejo, D | 1 |
| Lissoni, P | 3 |
| Barni, S | 3 |
| Rovelli, F | 3 |
| Brivio, F | 1 |
| Ardizzoia, A | 1 |
| Tancini, G | 3 |
| Conti, A | 1 |
| Maestroni, GJ | 1 |
| Poon, AM | 1 |
| Mak, AS | 1 |
| Luk, HT | 1 |
| Popovich, IG | 4 |
| Muratov, EI | 1 |
| Zabezhinski, MA | 3 |
| Papazisis, KT | 1 |
| Kouretas, D | 1 |
| Geromichalos, GD | 1 |
| Sivridis, E | 1 |
| Tsekreli, OK | 1 |
| Dimitriadis, KA | 1 |
| Kortsaris, AH | 1 |
| Kvetnoy, IM | 1 |
| Chumakova, NK | 1 |
| Kvetnaya, TV | 1 |
| Molotkov, AO | 1 |
| Pogudina, NA | 1 |
| Popuchiev, VV | 1 |
| Bartsch, H | 1 |
| Bartsch, C | 1 |
| Vician, M | 1 |
| Zeman, M | 1 |
| Herichová, I | 1 |
| Juráni, M | 1 |
| Blazícek, P | 1 |
| Matis, P | 1 |
| Shtylik, AV | 1 |
| Ben-Huh, H | 1 |
| Gurevich, P | 1 |
| Berman, V | 1 |
| Tendler, Y | 1 |
| Zusman, I | 1 |
| Kunert-Radek, J | 2 |
| Melen-Mucha, G | 1 |
| Gruszka, A | 1 |
| Spadoni, G | 1 |
| Tarzia, G | 1 |
| Esposti, D | 1 |
| Crispino, S | 2 |
| Paolorossi, F | 2 |
| Ferri, L | 1 |
| Cattaneo, G | 2 |
| Esposti, G | 1 |
| Fraschini, F | 1 |
| Khoory, R | 1 |
| Stemme, D | 1 |
| Levin, IM | 1 |
4 reviews available for melatonin and Cancer of Colon
| Article | Year |
|---|---|
Melatonin and 5-fluorouracil combination chemotherapy: opportunities and efficacy in cancer therapy.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Fluorouracil; Humans; Melaton | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
New paradigms in chronic intestinal inflammation and colon cancer: role of melatonin.
Topics: Animals; Autophagy; Chronic Disease; Colonic Neoplasms; Humans; Inflammatory Bowel Diseases; Melaton | 2011 |
[Light-dark conditions, melatonin and risk of cancer].
Topics: Animals; Breast Neoplasms; Circadian Rhythm; Colonic Neoplasms; Darkness; Female; Humans; Life Style | 2006 |
1 trial available for melatonin and Cancer of Colon
39 other studies available for melatonin and Cancer of Colon
| Article | Year |
|---|---|
Melatonin Enhances Anti-tumoral Effects of Menadione on Colon Cancer Cells.
Topics: Antioxidants; Buthionine Sulfoximine; Caco-2 Cells; Colonic Neoplasms; Humans; Melatonin; Oxidative | 2022 |
Melatonin and andrographolide synergize to inhibit the colospheroid phenotype by targeting Wnt/beta-catenin signaling.
Topics: beta Catenin; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Diterpenes; Humans; Melatonin | 2022 |
Combination of Irinotecan and Melatonin with the Natural Compounds Wogonin and Celastrol for Colon Cancer Treatment.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Humans; Irinotecan; Melatonin | 2023 |
Synergistic potential of dual andrographolide and melatonin targeting of metastatic colon cancer cells: Using the Chou-Talalay combination index method.
Topics: Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Cell Survival; Colonic Neop | 2021 |
The Impact of Melatonin on Colon Cancer Cells' Resistance to Doxorubicin in an in Vitro Study.
Topics: Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Membe | 2017 |
Melatonin inhibits colon cancer RKO cell migration by downregulating Rho‑associated protein kinase expression via the p38/MAPK signaling pathway.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Line, Tumor; Cell Movement; Cell Proliferation; | 2017 |
Melatonin and 5-fluorouracil co-suppress colon cancer stem cells by regulating cellular prion protein-Oct4 axis.
Topics: Aged; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Autophagy; Colon; Colonic Neoplasms; | 2018 |
The Effect of Melatonin on Superoxide Dismutase and Glutathione Peroxidase Activity, and Malondialdehyde Levels in the Targeted and the Non-targeted Lung and Heart Tissues after Irradiation in Xenograft Mice Colon Cancer.
Topics: Animals; Antioxidants; Colonic Neoplasms; Glutathione Peroxidase; Heart; Humans; Lung; Male; Malondi | 2018 |
Melatonin reduces endothelin-1 expression and secretion in colon cancer cells through the inactivation of FoxO-1 and NF-κβ.
Topics: Base Sequence; Caco-2 Cells; Colonic Neoplasms; Endothelin-1; Forkhead Box Protein O1; Forkhead Tran | 2014 |
Pineal gland function is required for colon antipreneoplastic effects of physical exercise in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Colonic Neoplasms; Cyclooxygenase 2; DNA; DNA Damage; Enteric Nervou | 2015 |
Melatonin modulated autophagy and Nrf2 signaling pathways in mice with colitis-associated colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Autophagy; Carcinogenesis; Carcinogens; Col | 2016 |
Melatonin inhibits the Migration of Colon Cancer RKO cells by Down-regulating Myosin Light Chain Kinase Expression through Cross-talk with p38 MAPK.
Topics: Antioxidants; Apoptosis; Blotting, Western; Cell Movement; Cell Proliferation; Colonic Neoplasms; Do | 2015 |
Multitargeting activity of miR-24 inhibits long-term melatonin anticancer effects.
Topics: Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Breast Neoplasms; Case-Control Studies; Cell Pr | 2016 |
[ASSESSMENT OF EFFICACY OF MELATONIN IN SURGICAL TREATMENT OF COLON TUMORS].
Topics: Aged; Antioxidants; Colonic Neoplasms; Female; Humans; Interleukin-10; Interleukin-1beta; Interleuki | 2015 |
Melatonin synergizes the chemotherapeutic effect of 5-fluorouracil in colon cancer by suppressing PI3K/AKT and NF-κB/iNOS signaling pathways.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Cell Line, Tu | 2017 |
[Colon carcinogenesis in rat vs. variable light].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Antioxidants; Carcinogens; Cell Differentiation; Cel | 2008 |
Melatonin suppresses AOM/DSS-induced large bowel oncogenesis in rats.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Azoxymethane; Biomarkers, Tumor; Colon; C | 2009 |
Luzindole but not 4-phenyl-2- propionamidotetralin (4P-PDOT) diminishes the inhibitory effect of melatonin on murine Colon 38 cancer growth in vitro.
Topics: Animals; Cell Line, Tumor; Colonic Neoplasms; Humans; Melatonin; Mice; Receptors, Melatonin; Tetrahy | 2009 |
Melatonin suppresses tumor angiogenesis by inhibiting HIF-1alpha stabilization under hypoxia.
Topics: Antioxidants; Cell Hypoxia; Cells, Cultured; Colonic Neoplasms; Culture Media, Conditioned; Humans; | 2010 |
[Neuroendocrine changes in patients with inflammatory diseases and colonic cancer].
Topics: Apoptosis; Cell Proliferation; Colitis, Ulcerative; Colonic Neoplasms; Crohn Disease; Free Radicals; | 2010 |
The melatonin action on stromal stem cells within pericryptal area in colon cancer model under constant light.
Topics: Animals; Colon; Colonic Neoplasms; Light; Male; Melatonin; Neoplastic Stem Cells; Rats; Rats, Wistar | 2011 |
Melatonin potentiates the antiproliferative and pro-apoptotic effects of ursolic acid in colon cancer cells by modulating multiple signaling pathways.
Topics: Apoptosis; Base Sequence; Cell Line, Tumor; Cell Proliferation; Chromatin Immunoprecipitation; Colon | 2013 |
Melatonin potentiates flavone-induced apoptosis in human colon cancer cells by increasing the level of glycolytic end products.
Topics: Antioxidants; Apoptosis; Caspase 3; Caspases; Cell Nucleus; Colonic Neoplasms; DNA Damage; Flavones; | 2005 |
Cellular mechanisms involved in the melatonin inhibition of HT-29 human colon cancer cell proliferation in culture.
Topics: Cell Proliferation; Colonic Neoplasms; Glutathione; Glutathione Peroxidase; Glutathione Reductase; H | 2007 |
Neuroimmunotherapy of advanced solid neoplasms with single evening subcutaneous injection of low-dose interleukin-2 and melatonin: preliminary results.
Topics: Adult; Aged; Biopterins; Breast Neoplasms; Colonic Neoplasms; Drug Therapy, Combination; Eosinophils | 1993 |
Melatonin and 2[125I]iodomelatonin binding sites in the human colon.
Topics: Aged; Aged, 80 and over; Autoradiography; Binding Sites; Colonic Neoplasms; Female; Humans; Intestin | 1996 |
[Effect of melatonin on 1,2-dimethylhydrazine-induced intestinal tumors in rats].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; | 1996 |
Melatonin and colon carcinogenesis: I. Inhibitory effect of melatonin on development of intestinal tumors induced by 1,2-dimethylhydrazine in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Anticarcinogenic Agents; Body Weight; Colonic Neopla | 1997 |
Effects of melatonin on proliferation of cancer cell lines.
Topics: Breast Neoplasms; Buthionine Sulfoximine; Cell Division; Cell Survival; Colonic Neoplasms; DNA Repli | 1998 |
Melatonin and colon carcinogenesis. II. Intestinal melatonin-containing cells and serum melatonin level in rats with 1,2-dimethylhydrazine-induced colon tumors.
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Carcinogens; Cell Count; Circadian Rhythm; | 1999 |
Melatonin content in plasma and large intestine of patients with colorectal carcinoma before and after surgery.
Topics: Aged; Circadian Rhythm; Colon; Colonic Neoplasms; Female; Humans; Hydroxyindoleacetic Acid; Intestin | 1999 |
Melatonin and colon carcinogenesis. III. Effect of melatonin on proliferative activity and apoptosis in colon mucosa and colon tumors induced by 1,2-dimethylhydrazine in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Apoptosis; Carcinogens; Cell Division; Colonic Neopl | 2000 |
The antiproliferative effects of melatonin on experimental pituitary and colonic tumors. Possible involvement of the putative nuclear binding site?
Topics: Animals; Cell Division; Cell Nucleus; Colonic Neoplasms; Diethylstilbestrol; Male; Melatonin; Mice; | 1999 |
Melatonin and RZR/ROR receptor ligand CGP 52608 induce apoptosis in the murine colonic cancer.
Topics: Animals; Apoptosis; Colonic Neoplasms; Ligands; Male; Melatonin; Mice; Mice, Inbred C57BL; Mice, Inb | 2001 |
Effects of melatonin and melatonin receptors ligand N-[(4-methoxy-1H-indol-2-yl)methyl]propanamide on murine Colon 38 cancer growth in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Bromodeoxyuridine; Cell Division; Colonic N | 2002 |
A study on the relationship between the pineal gland and the opioid system in patients with cancer. Preliminary considerations.
Topics: Adult; beta-Endorphin; Breast Neoplasms; Colonic Neoplasms; Endorphins; Female; Growth Hormone; Huma | 1988 |
Melatonin increase as predictor for tumor objective response to chemotherapy in advanced cancer patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Colonic Neoplasms; Female; Humans; | 1988 |
Plasma melatonin levels in patients suffering from colorectal carcinoma.
Topics: Aged; Aged, 80 and over; Carcinoembryonic Antigen; Carcinoma; Circadian Rhythm; Colonic Neoplasms; H | 1988 |
[Daily excretion of melatonin in patients with cancer of the stomach and large intestine].
Topics: Circadian Rhythm; Colonic Neoplasms; Female; Humans; Male; Melatonin; Middle Aged; Stomach Neoplasms | 1987 |