melatonin has been researched along with Cancer of Cervix in 13 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The pineal hormone melatonin has been reported to have in vitro antiproliferative effects on estrogen receptor-positive human breast cancer cell lines at concentrations near to plasma physiological concentrations (1 x 10(-11) to 1 x 10(-9) M)." | 3.70 | Effects of melatonin on proliferation of cancer cell lines. ( Dimitriadis, KA; Geromichalos, GD; Kortsaris, AH; Kouretas, D; Papazisis, KT; Sivridis, E; Tsekreli, OK, 1998) |
| "Melatonin is an indolamine compound secreted from the pineal gland which shows wide range anticancer activities." | 2.61 | Melatonin: A new inhibitor agent for cervical cancer treatment. ( Asemi, Z; Mirzaei, H; Reiter, RJ; Shafabakhsh, R; Teymoordash, SN, 2019) |
| "Cervical cancer is the fourth most common malignancy in women globally." | 1.91 | Melatonin synergistically enhances docetaxel induced endoplasmic reticulum stress to promote apoptosis by suppressing NF-κB activation in cervical cancer. ( Song, Y; Wang, S, 2023) |
| "Cervical cancer is the most prevalent cancer in females." | 1.72 | Melatonin induces apoptosis and cell cycle arrest in cervical cancer cells via inhibition of NF-κB pathway. ( Awasthee, N; Das, M; Gupta, SC; Haldar, C; Minocha, T; Rai, V; Verma, SS; Yadav, SK, 2022) |
| "The radiation response of cervical cancer is thought to be enhanced by the levels of melatonin due to its roles in the circadian cycle and cancer growth." | 1.72 | Circadian as a prognostic factor for radiation responses in patients with cervical cancer: A nested case‑control study. ( Harahap, AR; Mansyur, M; Nuranna, L; Ramli, I; Siregar, NC; Soetopo, S; Susworo, S; Wanandi, SI, 2022) |
| "Cervical cancer has poor prognosis and patients are often diagnosed at advanced stages of the disease with limited treatment options." | 1.51 | Inhibition of SGK1 confers vulnerability to redox dysregulation in cervical cancer. ( Cheng, H; Liu, P; Qin, P; Sang, X; Shen, L; Tao, Z; Wang, J; Wang, M; Xue, Y; Yi, J, 2019) |
| "Melatonin has antitumor activity via several mechanisms including its antiproliferative and pro-apoptotic effects as well as its potent antioxidant actions, although recent evidence has indicated that melatonin may perform pro-oxidant actions in tumor cells." | 1.43 | Melatonin sensitizes human cervical cancer HeLa cells to cisplatin-induced cytotoxicity and apoptosis: effects on oxidative stress and DNA fragmentation. ( Espino, J; Pariente, JA; Pariente, R; Rodríguez, AB, 2016) |
| "Melatonin concentration was measured by immunoenzymatic method." | 1.33 | Serum melatonin circadian profiles in women suffering from cervical cancer. ( Karasek, M; Kowalski, AJ; Suzin, J; Swietoslawski, J; Zylinska, K, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 4 (30.77) | 2.80 |
| Authors | Studies |
|---|---|
| Minocha, T | 1 |
| Das, M | 1 |
| Rai, V | 1 |
| Verma, SS | 1 |
| Awasthee, N | 1 |
| Gupta, SC | 1 |
| Haldar, C | 1 |
| Yadav, SK | 1 |
| Ramli, I | 1 |
| Susworo, S | 1 |
| Nuranna, L | 1 |
| Mansyur, M | 1 |
| Harahap, AR | 1 |
| Soetopo, S | 1 |
| Siregar, NC | 1 |
| Wanandi, SI | 1 |
| Song, Y | 1 |
| Wang, S | 1 |
| Cotrim, ACM | 1 |
| França, EL | 1 |
| Martins, JS | 1 |
| Silva, KPG | 1 |
| Fujimori, M | 1 |
| Ghalfi, YC | 1 |
| Machado, IT | 1 |
| Honorio-França, AC | 1 |
| Tozetti, IA | 1 |
| de Almeida Chuffa, LG | 1 |
| Seiva, FRF | 1 |
| Cucielo, MS | 1 |
| Silveira, HS | 1 |
| Reiter, RJ | 3 |
| Lupi, LA | 1 |
| Shafabakhsh, R | 1 |
| Mirzaei, H | 1 |
| Teymoordash, SN | 1 |
| Asemi, Z | 1 |
| Wang, M | 1 |
| Xue, Y | 1 |
| Shen, L | 1 |
| Qin, P | 1 |
| Sang, X | 1 |
| Tao, Z | 1 |
| Yi, J | 1 |
| Wang, J | 1 |
| Liu, P | 1 |
| Cheng, H | 1 |
| Pariente, R | 1 |
| Pariente, JA | 1 |
| Rodríguez, AB | 1 |
| Espino, J | 1 |
| Zwirska-Korczala, K | 1 |
| Adamczyk-Sowa, M | 1 |
| Polaniak, R | 1 |
| Sowa, P | 1 |
| Birkner, E | 1 |
| Drzazga, Z | 1 |
| Brzozowski, T | 1 |
| Konturek, SJ | 1 |
| Karasek, M | 1 |
| Kowalski, AJ | 1 |
| Suzin, J | 1 |
| Zylinska, K | 1 |
| Swietoslawski, J | 1 |
| Chen, LD | 1 |
| Leal, BZ | 1 |
| Abe, M | 1 |
| Sewerynek, E | 1 |
| Melchiorri, D | 1 |
| Meltz, ML | 1 |
| Poeggeler, B | 1 |
| Papazisis, KT | 1 |
| Kouretas, D | 1 |
| Geromichalos, GD | 1 |
| Sivridis, E | 1 |
| Tsekreli, OK | 1 |
| Dimitriadis, KA | 1 |
| Kortsaris, AH | 1 |
| Anisimov, VN | 1 |
| Zabezhinski, MA | 1 |
| Popovich, IG | 1 |
| Zaripova, EA | 1 |
| Musatov, SA | 1 |
| Andre, V | 1 |
| Vigreux, C | 1 |
| Godard, T | 1 |
| Sichel, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Influence of Radiation Patterns Following Circadian Rhythm Upon Response of Radiotherapy of Uterine Cervical Cancer : Melatonin as a Radiosensitivity and Biological Marker[NCT05511740] | 71 participants (Actual) | Interventional | 2010-01-31 | Completed | |||
| The Effect of Physical Activity and Abstain From Smoking on the Regression of Precancerous Lesion.[NCT03093623] | 446 participants (Anticipated) | Interventional | 2014-10-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for melatonin and Cancer of Cervix
| Article | Year |
|---|---|
Mitochondrial functions and melatonin: a tour of the reproductive cancers.
Topics: Animals; Breast Neoplasms; Endometrial Neoplasms; Female; Genital Neoplasms, Female; Humans; Male; M | 2019 |
Melatonin: A new inhibitor agent for cervical cancer treatment.
Topics: Animals; Antineoplastic Agents; Female; Humans; Melatonin; Uterine Cervical Neoplasms | 2019 |
11 other studies available for melatonin and Cancer of Cervix
| Article | Year |
|---|---|
Melatonin induces apoptosis and cell cycle arrest in cervical cancer cells via inhibition of NF-κB pathway.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferati | 2022 |
Circadian as a prognostic factor for radiation responses in patients with cervical cancer: A nested case‑control study.
Topics: Case-Control Studies; Circadian Rhythm; Female; Hemoglobins; Humans; Melatonin; Middle Aged; Prognos | 2022 |
Melatonin synergistically enhances docetaxel induced endoplasmic reticulum stress to promote apoptosis by suppressing NF-κB activation in cervical cancer.
Topics: Apoptosis; Cell Line, Tumor; Docetaxel; Endoplasmic Reticulum Stress; Female; Humans; Melatonin; NF- | 2023 |
Correlation between melatonin concentration and cytokines in cervical mucus in positive samples for the presence of human papillomavirus.
Topics: Adult; Biomarkers; Cervix Mucus; Cytokines; DNA, Viral; Female; Histocytochemistry; Humans; Liquid B | 2021 |
Inhibition of SGK1 confers vulnerability to redox dysregulation in cervical cancer.
Topics: Animals; Antioxidants; Apoptosis; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; | 2019 |
Melatonin sensitizes human cervical cancer HeLa cells to cisplatin-induced cytotoxicity and apoptosis: effects on oxidative stress and DNA fragmentation.
Topics: Apoptosis; Cisplatin; Cytotoxins; DNA Fragmentation; DNA, Neoplasm; Female; HeLa Cells; Humans; Mela | 2016 |
Influence of extremely-low-frequency magnetic field on antioxidative melatonin properties in AT478 murine squamous cell carcinoma culture.
Topics: Animals; Antioxidants; Carcinoma, Squamous Cell; Cell Line, Tumor; Electromagnetic Fields; Female; G | 2004 |
Serum melatonin circadian profiles in women suffering from cervical cancer.
Topics: Biomarkers, Tumor; Circadian Rhythm; Female; Humans; Melatonin; Middle Aged; Neoplasm Staging; Uteri | 2005 |
Melatonin's inhibitory effect on growth of ME-180 human cervical cancer cells is not related to intracellular glutathione concentrations.
Topics: Cell Division; Female; Glutathione; Growth Inhibitors; Humans; In Vitro Techniques; Melatonin; Methi | 1995 |
Effects of melatonin on proliferation of cancer cell lines.
Topics: Breast Neoplasms; Buthionine Sulfoximine; Cell Division; Cell Survival; Colonic Neoplasms; DNA Repli | 1998 |
Inhibitory effect of melatonin on 7, 12-dimethylbenz[a]anthracene-induced carcinogenesis of the uterine cervix and vagina in mice and mutagenesis in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antimutagenic Agents; Carcinogen | 2000 |