melatonin has been researched along with Cachexia in 11 studies
Cachexia: General ill health, malnutrition, and weight loss, usually associated with chronic disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Prior studies have suggested that melatonin, a frequently used integrative medicine, can attenuate weight loss, anorexia, and fatigue in patients with cancer." | 9.17 | Effects of melatonin on appetite and other symptoms in patients with advanced cancer and cachexia: a double-blind placebo-controlled trial. ( Bruera, E; Del Fabbro, E; Dev, R; Hui, D; Palmer, L, 2013) |
| "The effect of fish oil (FO), melatonin (MLT), or their combination and dietary advice on cachexia and biochemistry variables reflecting cachexia were investigated in patients with advanced gastrointestinal cancer." | 9.11 | Impact of fish oil and melatonin on cachexia in patients with advanced gastrointestinal cancer: a randomized pilot study. ( Glimelius, B; Nygren, P; Persson, C; Rönnelid, J, 2005) |
| "Prior studies have suggested that melatonin, a frequently used integrative medicine, can attenuate weight loss, anorexia, and fatigue in patients with cancer." | 5.17 | Effects of melatonin on appetite and other symptoms in patients with advanced cancer and cachexia: a double-blind placebo-controlled trial. ( Bruera, E; Del Fabbro, E; Dev, R; Hui, D; Palmer, L, 2013) |
| "The effect of fish oil (FO), melatonin (MLT), or their combination and dietary advice on cachexia and biochemistry variables reflecting cachexia were investigated in patients with advanced gastrointestinal cancer." | 5.11 | Impact of fish oil and melatonin on cachexia in patients with advanced gastrointestinal cancer: a randomized pilot study. ( Glimelius, B; Nygren, P; Persson, C; Rönnelid, J, 2005) |
| "Cancer cachexia is a multi-organ syndrome with unintentional weight loss, sarcopenia, and systemic inflammation." | 3.01 | Relevance of Dietary Supplement Use in Gastrointestinal-Cancer-Associated Cachexia. ( Grundmann, O; Yoon, SL, 2023) |
| "Studies have recruited heterogeneous cancer patient populations in late disease stages, and many had issues with accrual and attrition." | 2.61 | Anti-cytokines in the treatment of cancer cachexia. ( Prado, BL; Qian, Y, 2019) |
| "Patients with cancer frequently experience unintended weight loss due to gastrointestinal (GI) dysfunction caused by the malignancy or treatment of the malignancy." | 2.55 | Cancer Cachexia: Cause, Diagnosis, and Treatment. ( Mattox, TW, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 6 (54.55) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Yoon, SL | 1 |
| Grundmann, O | 1 |
| Ballyuzek, MF | 1 |
| Mashkova, MV | 1 |
| Arutjunyan, AV | 1 |
| Duke, VA | 1 |
| Mattox, TW | 1 |
| Prado, BL | 1 |
| Qian, Y | 1 |
| Jafari-Vayghan, H | 1 |
| Saleh-Ghadimi, S | 1 |
| Maleki, V | 1 |
| Moludi, J | 1 |
| Alizadeh, M | 1 |
| Baracos, VE | 1 |
| Del Fabbro, E | 1 |
| Dev, R | 1 |
| Hui, D | 1 |
| Palmer, L | 1 |
| Bruera, E | 2 |
| Persson, C | 1 |
| Glimelius, B | 1 |
| Rönnelid, J | 1 |
| Nygren, P | 1 |
| Lissoni, P | 1 |
| Paolorossi, F | 1 |
| Tancini, G | 1 |
| Barni, S | 1 |
| Ardizzoia, A | 1 |
| Brivio, F | 1 |
| Zubelewicz, B | 1 |
| Chatikhine, V | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Assessing Quality of Life and the Feasibility of a Nutrition and Pharmacological Algorithm for Oncology Patients With Anorexia[NCT04155008] | Phase 4 | 1 participants (Actual) | Interventional | 2021-03-01 | Terminated (stopped due to The trial was closed after 4 months due to slow to accrual. Only 1 participant was enrolled.) | ||
| The Traditional Chinese Medicine Department of Xin Qiao Hospital[NCT02619266] | Phase 2/Phase 3 | 160 participants (Anticipated) | Interventional | 2015-12-31 | Recruiting | ||
| A Randomized Clinical Trial of Melatonin Versus Placebo and the Effect on Appetite in Advanced Cancer Patients[NCT00513357] | Phase 3 | 82 participants (Actual) | Interventional | 2006-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Difference in ESAS (Edmonton Symptom Assessment Scale) assessment scores of appetite (symptom) from baseline evaluation [± 3 days] to 4 week evaluation [± 3 days], where the severity at the time of assessment is rated from 0 to 10 on a numerical scale; with 0 meaning that the symptom is absent and 10 that it is the worst possible severity. (NCT00513357)
Timeframe: Baseline and at 4 weeks
| Intervention | units on a scale (Mean) |
|---|---|
| Melatonin | -0.83 |
| Placebo | -1.19 |
5 reviews available for melatonin and Cachexia
| Article | Year |
|---|---|
Relevance of Dietary Supplement Use in Gastrointestinal-Cancer-Associated Cachexia.
Topics: Cachexia; Dietary Supplements; Fatty Acids, Omega-3; Fish Oils; Gastrointestinal Neoplasms; Humans; | 2023 |
Cancer Cachexia: Cause, Diagnosis, and Treatment.
Topics: Anabolic Agents; Animals; Anti-Inflammatory Agents; Appetite Stimulants; Cachexia; Combined Modality | 2017 |
Anti-cytokines in the treatment of cancer cachexia.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Cachexia; Cytokines; Etanercept; Forecast | 2019 |
The effects of melatonin on neurohormonal regulation in cardiac cachexia: A mechanistic review.
Topics: Cachexia; Forkhead Box Protein O1; Heart Diseases; Humans; Insulin-Like Growth Factor I; Melatonin; | 2019 |
Pharmacological treatment of cachexia: any progress?
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Antiemetics; Antioxidants; Appetite Stimulants; C | 1998 |
3 trials available for melatonin and Cachexia
| Article | Year |
|---|---|
Effects of melatonin on appetite and other symptoms in patients with advanced cancer and cachexia: a double-blind placebo-controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Antioxidants; Appetite; Body Weight; Cachexia; Depression; Double-Bl | 2013 |
Effects of melatonin on appetite and other symptoms in patients with advanced cancer and cachexia: a double-blind placebo-controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Antioxidants; Appetite; Body Weight; Cachexia; Depression; Double-Bl | 2013 |
Effects of melatonin on appetite and other symptoms in patients with advanced cancer and cachexia: a double-blind placebo-controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Antioxidants; Appetite; Body Weight; Cachexia; Depression; Double-Bl | 2013 |
Effects of melatonin on appetite and other symptoms in patients with advanced cancer and cachexia: a double-blind placebo-controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Antioxidants; Appetite; Body Weight; Cachexia; Depression; Double-Bl | 2013 |
Impact of fish oil and melatonin on cachexia in patients with advanced gastrointestinal cancer: a randomized pilot study.
Topics: Aged; Aged, 80 and over; Antioxidants; Body Weight; Cachexia; Cross-Over Studies; Cytokines; Dietary | 2005 |
Is there a role for melatonin in the treatment of neoplastic cachexia?
Topics: Adult; Aged; Cachexia; Female; Humans; Male; Melatonin; Middle Aged; Neoplasm Metastasis; Palliative | 1996 |
3 other studies available for melatonin and Cachexia
| Article | Year |
|---|---|
[Melatonin as a marker of the grade of cardiac disorders during cachexia development in oncological patients of different ages].
Topics: Adult; Age Factors; Aged; Biomarkers; Cachexia; False Positive Reactions; Heart Diseases; Humans; Me | 2017 |
Clinical trials of cancer cachexia therapy, now and hereafter.
Topics: Appetite; Cachexia; Female; Humans; Male; Melatonin; Neoplasms | 2013 |
[The tumor-cahexy syndrome. Poor general health--a complex problem].
Topics: Anorexia; Antineoplastic Combined Chemotherapy Protocols; Cachexia; Cisplatin; Etoposide; Gastrointe | 1998 |