melatonin has been researched along with Brain Infarction in 7 studies
Brain Infarction: Tissue NECROSIS in any area of the brain, including the CEREBRAL HEMISPHERES, the CEREBELLUM, and the BRAIN STEM. Brain infarction is the result of a cascade of events initiated by inadequate blood flow through the brain that is followed by HYPOXIA and HYPOGLYCEMIA in brain tissue. Damage may be temporary, permanent, selective or pan-necrosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Melatonin (15 mg/kg) was administered by intraperitoneal injection at 1, 24, 48, and 72 h." | 5.35 | Long-term effects of melatonin after intracerebral hemorrhage in rats. ( Ayer, R; Hartman, RE; Jadhav, V; Lee, S; Lekic, T; Rojas, HA; Tang, J; Titova, E; Zhang, JH, 2008) |
| "By day 28 after IS, the brain infarct area (BIA) was lowest in group 1, highest in group 2, significantly higher in groups 3 and 4 than in group 5, but not different between groups 3 and 4." | 1.51 | Combined Therapy With Hyperbaric Oxygen and Melatonin Effectively Reduce Brain Infarct Volume and Preserve Neurological Function After Acute Ischemic Infarct in Rat. ( Chen, KH; Chen, YL; Ko, SF; Lee, MS; Lin, KC; Wallace, CG; Yip, HK, 2019) |
| "Melatonin also reduced reactive gliosis." | 1.38 | Histological study of the protective effect of melatonin on neural cells after neonatal hypoxia-ischemia. ( Alonso-Alconada, D; Alvarez, A; Hilario, E; Lacalle, J, 2012) |
| "Melatonin was given i." | 1.37 | Melatonin promotes myelination by decreasing white matter inflammation after neonatal stroke. ( Baud, O; Biran, V; Charriaut-Marlangue, C; Fau, S; Renolleau, S; Villapol, S, 2011) |
| "Melatonin (15 mg/kg) was administered by intraperitoneal injection at 1, 24, 48, and 72 h." | 1.35 | Long-term effects of melatonin after intracerebral hemorrhage in rats. ( Ayer, R; Hartman, RE; Jadhav, V; Lee, S; Lekic, T; Rojas, HA; Tang, J; Titova, E; Zhang, JH, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, KC | 1 |
| Chen, KH | 1 |
| Wallace, CG | 1 |
| Chen, YL | 1 |
| Ko, SF | 1 |
| Lee, MS | 1 |
| Yip, HK | 1 |
| Kelestemur, T | 1 |
| Yulug, B | 1 |
| Caglayan, AB | 1 |
| Beker, MC | 1 |
| Kilic, U | 1 |
| Caglayan, B | 1 |
| Yalcin, E | 1 |
| Gundogdu, RZ | 1 |
| Kilic, E | 1 |
| Hung, YC | 1 |
| Chen, TY | 1 |
| Lee, EJ | 1 |
| Chen, WL | 1 |
| Huang, SY | 1 |
| Lee, WT | 1 |
| Lee, MY | 1 |
| Chen, HY | 1 |
| Wu, TS | 1 |
| Hartman, RE | 1 |
| Rojas, HA | 1 |
| Lekic, T | 1 |
| Ayer, R | 1 |
| Lee, S | 1 |
| Jadhav, V | 1 |
| Titova, E | 1 |
| Tang, J | 1 |
| Zhang, JH | 1 |
| Villapol, S | 1 |
| Fau, S | 1 |
| Renolleau, S | 1 |
| Biran, V | 1 |
| Charriaut-Marlangue, C | 1 |
| Baud, O | 1 |
| Alonso-Alconada, D | 1 |
| Alvarez, A | 1 |
| Lacalle, J | 1 |
| Hilario, E | 1 |
| Ozyener, F | 1 |
| Çetinkaya, M | 1 |
| Alkan, T | 1 |
| Gören, B | 1 |
| Kafa, IM | 1 |
| Kurt, MA | 1 |
| Koksal, N | 1 |
1 trial available for melatonin and Brain Infarction
| Article | Year |
|---|---|
Neuroprotective effects of melatonin administered alone or in combination with topiramate in neonatal hypoxic-ischemic rat model.
Topics: Analysis of Variance; Animals; Animals, Newborn; Brain; Brain Infarction; Caspase 3; Cell Count; Cel | 2012 |
6 other studies available for melatonin and Brain Infarction
| Article | Year |
|---|---|
Combined Therapy With Hyperbaric Oxygen and Melatonin Effectively Reduce Brain Infarct Volume and Preserve Neurological Function After Acute Ischemic Infarct in Rat.
Topics: Animals; Apoptosis; Brain; Brain Infarction; Brain Ischemia; Disease Models, Animal; Hyperbaric Oxyg | 2019 |
Targeting different pathophysiological events after traumatic brain injury in mice: Role of melatonin and memantine.
Topics: Animals; Brain; Brain Infarction; Brain Injuries; DNA Fragmentation; Free Radical Scavengers; Male; | 2016 |
Melatonin decreases matrix metalloproteinase-9 activation and expression and attenuates reperfusion-induced hemorrhage following transient focal cerebral ischemia in rats.
Topics: Animals; Blotting, Western; Brain; Brain Infarction; Cerebral Hemorrhage; Enzyme Activation; Gene Ex | 2008 |
Long-term effects of melatonin after intracerebral hemorrhage in rats.
Topics: Animals; Antioxidants; Behavior, Animal; Brain Infarction; Cerebral Hemorrhage; Collagenases; Corpus | 2008 |
Melatonin promotes myelination by decreasing white matter inflammation after neonatal stroke.
Topics: Animals; Brain Infarction; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Infant, Newborn; | 2011 |
Histological study of the protective effect of melatonin on neural cells after neonatal hypoxia-ischemia.
Topics: Animals; Animals, Newborn; Apoptosis; Biomarkers; Brain; Brain Infarction; Demyelinating Diseases; D | 2012 |