melatonin has been researched along with Brain Diseases in 32 studies
Brain Diseases: Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "These studies demonstrate a significant neuroprotective efficacy of melatonin in term neonatal models of hypoxia-ischaemia, and suggest melatonin is a strong candidate for translation to clinical trials in babies with moderate-severe NE." | 9.22 | Efficacy of melatonin in term neonatal models of perinatal hypoxia-ischaemia. ( Golay, X; Han, HJ; Meehan, C; Miller, SL; Pang, R; Robertson, NJ, 2022) |
| "Improvements in encephalopathy and medical stabilization did not rapidly normalize rhythms." | 5.56 | Factors Disrupting Melatonin Secretion Rhythms During Critical Illness. ( Abbott, SM; Eed, J; Gendy, M; Liotta, EM; Lizza, BD; Maas, MB; Naidech, AM; Reid, KJ; Zee, PC, 2020) |
| "These studies demonstrate a significant neuroprotective efficacy of melatonin in term neonatal models of hypoxia-ischaemia, and suggest melatonin is a strong candidate for translation to clinical trials in babies with moderate-severe NE." | 5.22 | Efficacy of melatonin in term neonatal models of perinatal hypoxia-ischaemia. ( Golay, X; Han, HJ; Meehan, C; Miller, SL; Pang, R; Robertson, NJ, 2022) |
| "Depression, peptic ulcers, and sexual dysfunction may be exacerbated by a deficiency of melatonin." | 4.76 | Disorder of the pineal gland associated with depression, peptic ulcers, and sexual dysfunction. ( Maurizi, CP, 1984) |
| "In 66 patients with some diseases of the nervous system (epilepsy, brain tumors, traumatic brain lesions, discorgenic lumbosacral radiculitis) melatonin content in liquor was determined by a fluorimetric method, especially modified for this purpose." | 3.65 | [Cerebrospinal fluid melatonin in diseases of the nervous system]. ( Kiselev, VN; Loboda, EB; Makarov, AIu, 1977) |
| "Neonatal encephalopathy is a leading cause of morbidity and mortality worldwide." | 2.72 | Melatonin for Neonatal Encephalopathy: From Bench to Bedside. ( Advic-Belltheus, A; Fullen, DJ; Golay, X; Meehan, C; Pang, R; Robertson, NJ, 2021) |
| "Melatonin has been suggested an adjunctive therapy in neonatal encephalopathy (NE)." | 1.91 | Melatonin Alters Innate Immune Function in Infants with Neonatal Encephalopathy. ( Aslam, S; Branagan, A; Donoghue, V; Hurley, T; Kelly, LA; McKenna, E; Molloy, EJ; Murphy, J; Normile, C; O'Dea, M; O'Driscoll, D; O'Neill, A; Saleemi, S; Sweetman, D; Vavasseur, C; Watson, W, 2023) |
| "Improvements in encephalopathy and medical stabilization did not rapidly normalize rhythms." | 1.56 | Factors Disrupting Melatonin Secretion Rhythms During Critical Illness. ( Abbott, SM; Eed, J; Gendy, M; Liotta, EM; Lizza, BD; Maas, MB; Naidech, AM; Reid, KJ; Zee, PC, 2020) |
| "Cerebral injury after cardiac arrest (CA)/cardiopulmonary resuscitation (CPR) has been implicated in the poor prognosis of CA survivors." | 1.48 | Melatonin improves neurological outcomes and preserves hippocampal mitochondrial function in a rat model of cardiac arrest. ( Chen, Q; Deng, Y; Gong, C; Hai, K; Jiang, C; Li, H; Li, Q; Li, T; Wang, J; Wu, W; Yang, L; Zhou, R, 2018) |
| "Neurotoxicity is a burdensome consequence of platinum-based chemotherapy that neutralizes the administration of effective dosage and often prompts treatment withdrawal." | 1.43 | Neuroprotective effects of melatonin as evidenced by abrogation of oxaliplatin induced behavioral alterations, mitochondrial dysfunction and neurotoxicity in rat brain. ( Parvez, S; Tabassum, H; Waseem, M, 2016) |
| "Melatonin is a hormone that mostly produced from the pineal gland, and it performs as a strong neuroprotectant to both neuron and glial cells against methamphetamine (METH)-induced neurotoxicity." | 1.43 | Inhibitory effect of melatonin on cerebral endothelial cells dysfunction induced by methamphetamine via NADPH oxidase-2. ( Govitrapong, P; Jumnongprakhon, P; Tocharus, C; Tocharus, J, 2016) |
| "Treatment with melatonin 15 min after KA injection kept malondialdehyde levels and catalase and superoxide dismutase activities at the normal levels, and led to an increase in the levels of nitrite/nitrate." | 1.33 | The effect of melatonin on lipid peroxidation and nitrite/nitrate levels, and on superoxide dismutase and catalase activities in kainic acid-induced injury. ( Akcay, YD; Sozmen, EY; Yalcin, A, 2005) |
| "Melatonin production is an index, not of general sympathetic activity, but of the activity in a specific pathway and provides a stable humoral signal reflecting light/dark exposure." | 1.27 | Human melatonin in physiologic and diseased states: neural control of the rhythm. ( Vaughan, GM, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (18.75) | 18.7374 |
| 1990's | 10 (31.25) | 18.2507 |
| 2000's | 3 (9.38) | 29.6817 |
| 2010's | 8 (25.00) | 24.3611 |
| 2020's | 5 (15.63) | 2.80 |
| Authors | Studies |
|---|---|
| Pang, R | 2 |
| Han, HJ | 1 |
| Meehan, C | 2 |
| Golay, X | 2 |
| Miller, SL | 1 |
| Robertson, NJ | 2 |
| Aslam, S | 1 |
| O'Dea, M | 1 |
| Kelly, LA | 1 |
| O'Neill, A | 1 |
| McKenna, E | 1 |
| Hurley, T | 1 |
| Branagan, A | 1 |
| O'Driscoll, D | 1 |
| Normile, C | 1 |
| Saleemi, S | 1 |
| Sweetman, D | 1 |
| Vavasseur, C | 1 |
| Murphy, J | 1 |
| Donoghue, V | 1 |
| Watson, W | 1 |
| Molloy, EJ | 1 |
| Maas, MB | 1 |
| Lizza, BD | 1 |
| Abbott, SM | 1 |
| Liotta, EM | 1 |
| Gendy, M | 1 |
| Eed, J | 1 |
| Naidech, AM | 1 |
| Reid, KJ | 1 |
| Zee, PC | 1 |
| Advic-Belltheus, A | 1 |
| Fullen, DJ | 1 |
| Novais, AA | 1 |
| Chuffa, LGA | 1 |
| Zuccari, DAPC | 1 |
| Reiter, RJ | 2 |
| Yang, L | 1 |
| Wang, J | 1 |
| Deng, Y | 1 |
| Gong, C | 1 |
| Li, Q | 1 |
| Chen, Q | 1 |
| Li, H | 1 |
| Jiang, C | 1 |
| Zhou, R | 1 |
| Hai, K | 1 |
| Wu, W | 1 |
| Li, T | 1 |
| Paprocka, J | 1 |
| Kijonka, M | 1 |
| Borys, D | 1 |
| Emich-Widera, E | 1 |
| Wojcieszek, P | 1 |
| Sokół, M | 1 |
| Marseglia, L | 1 |
| D'Angelo, G | 1 |
| Manti, S | 1 |
| Aversa, S | 1 |
| Arrigo, T | 1 |
| Gitto, E | 1 |
| Fore, S | 1 |
| Waseem, M | 1 |
| Tabassum, H | 1 |
| Parvez, S | 1 |
| Jumnongprakhon, P | 1 |
| Govitrapong, P | 1 |
| Tocharus, C | 1 |
| Tocharus, J | 1 |
| Arushanian, EB | 1 |
| Meyer, S | 1 |
| Oberkircher, N | 1 |
| Böing, A | 1 |
| Larsen, A | 1 |
| Eymann, R | 1 |
| Kutschke, G | 1 |
| Akcay, YD | 1 |
| Yalcin, A | 1 |
| Sozmen, EY | 2 |
| Uyanikgil, Y | 1 |
| Baka, M | 1 |
| Ateş, U | 1 |
| Turgut, M | 1 |
| Yavaşoğlu, A | 1 |
| Ulker, S | 1 |
| Sezer, E | 1 |
| Elmas, C | 1 |
| Yurtseven, ME | 1 |
| Gressens, P | 1 |
| Schwendimann, L | 1 |
| Husson, I | 1 |
| Sarkozy, G | 1 |
| Mocaer, E | 1 |
| Vamecq, J | 1 |
| Spedding, M | 1 |
| Maurizi, CP | 1 |
| Rom-Bygoslavskaia, ES | 1 |
| Masuzawa, T | 1 |
| Tanaka, H | 1 |
| Kurokawa, N | 1 |
| Yamada, N | 1 |
| Giusti, P | 1 |
| Franceschini, D | 1 |
| Petrone, M | 1 |
| Manev, H | 1 |
| Floreani, M | 1 |
| Walker, AB | 1 |
| English, J | 1 |
| Arendt, J | 2 |
| MacFarlane, IA | 1 |
| Lerner, AB | 1 |
| Nordlund, JJ | 1 |
| Shaw, KM | 1 |
| Makarov, AIu | 1 |
| Kiselev, VN | 1 |
| Loboda, EB | 1 |
| Sandyk, R | 4 |
| Kay, SR | 1 |
| Bartness, TJ | 2 |
| Goldman, BD | 2 |
| Bittman, EL | 2 |
| DeVries, GJ | 1 |
| Bojkowski, CJ | 1 |
| Vaughan, GM | 1 |
10 reviews available for melatonin and Brain Diseases
| Article | Year |
|---|---|
Efficacy of melatonin in term neonatal models of perinatal hypoxia-ischaemia.
Topics: Animals; Brain Diseases; Humans; Hypothermia, Induced; Hypoxia; Infant, Newborn; Infant, Newborn, Di | 2022 |
Melatonin for Neonatal Encephalopathy: From Bench to Bedside.
Topics: Animals; Brain Diseases; Humans; Hypothermia, Induced; Infant, Newborn; Infant, Newborn, Diseases; M | 2021 |
Exosomes and Melatonin: Where Their Destinies Intersect.
Topics: Animals; Brain Diseases; Colitis; Exosomes; Humans; Kidney Diseases; Liver Diseases; Melatonin; Neop | 2021 |
Analgesic, anxiolytic and anaesthetic effects of melatonin: new potential uses in pediatrics.
Topics: Analgesics; Anesthetics, General; Anti-Anxiety Agents; Anxiety Disorders; Brain Diseases; Child; Ele | 2015 |
[Pineal hormone melatonin in complex pharmacotherapy of brain and somatic disorders].
Topics: Animals; Brain Diseases; Cardiovascular Diseases; Drug Synergism; Drug Therapy, Combination; Gastroi | 2011 |
Disorder of the pineal gland associated with depression, peptic ulcers, and sexual dysfunction.
Topics: Biological Clocks; Brain Diseases; Depressive Disorder; Female; Humans; Male; Melatonin; Peptic Ulce | 1984 |
[Pineal gland and melatonin].
Topics: Animals; Brain Diseases; Humans; Melatonin; Pineal Gland; Pituitary Gland, Anterior | 1995 |
The pineal gland: a review of the biochemistry, physiology and pharmacological potential of melatonin and other pineal substances.
Topics: Animals; Brain; Brain Diseases; Brain Neoplasms; Calcinosis; Circadian Rhythm; Endocrine Glands; Epi | 1977 |
Magnetic fields in the therapy of parkinsonism.
Topics: Aged; Brain; Brain Diseases; Cognition Disorders; Dopamine; Electromagnetic Fields; Female; Function | 1992 |
Successful treatment of multiple sclerosis with magnetic fields.
Topics: Brain; Brain Diseases; Chronic Disease; Demyelinating Diseases; Electromagnetic Fields; Female; Huma | 1992 |
22 other studies available for melatonin and Brain Diseases
| Article | Year |
|---|---|
Melatonin Alters Innate Immune Function in Infants with Neonatal Encephalopathy.
Topics: ARNTL Transcription Factors; Brain Diseases; Humans; Immunity; Infant; Infant, Newborn; Lipopolysacc | 2023 |
Factors Disrupting Melatonin Secretion Rhythms During Critical Illness.
Topics: Academic Medical Centers; Adult; Aged; Aged, 80 and over; Arousal; Brain Diseases; Cerebral Hemorrha | 2020 |
Melatonin improves neurological outcomes and preserves hippocampal mitochondrial function in a rat model of cardiac arrest.
Topics: Adenosine Triphosphate; Animals; Brain Diseases; Cardiopulmonary Resuscitation; Disease Models, Anim | 2018 |
Mathematical evaluation of melatonin secretion in hypoxic ischemic encephalopathy.
Topics: Brain Diseases; Child; Child, Preschool; Female; Hip Joint; Humans; Hypoxia-Ischemia, Brain; Knee; M | 2018 |
Evidence of Pineal Gland Calcification on CBCT is Not Insignificant: What Else You Might Discover about Your Patient.
Topics: Brain Diseases; Calcinosis; Cone-Beam Computed Tomography; Humans; Incidental Findings; Melatonin; P | 2016 |
Neuroprotective effects of melatonin as evidenced by abrogation of oxaliplatin induced behavioral alterations, mitochondrial dysfunction and neurotoxicity in rat brain.
Topics: Animals; Antineoplastic Agents; Brain Diseases; Male; Melatonin; Mitochondria; Neuroprotective Agent | 2016 |
Inhibitory effect of melatonin on cerebral endothelial cells dysfunction induced by methamphetamine via NADPH oxidase-2.
Topics: Animals; Apoptosis; Blood-Brain Barrier; Brain; Brain Diseases; Central Nervous System Stimulants; C | 2016 |
Disturbance in melatonin metabolism as a causative factor for recurrent headaches in a girl with a pineal cyst?
Topics: Adolescent; Biomarkers; Brain Diseases; Cysts; Female; Headache; Humans; Melatonin; Pineal Gland | 2013 |
The effect of melatonin on lipid peroxidation and nitrite/nitrate levels, and on superoxide dismutase and catalase activities in kainic acid-induced injury.
Topics: Animals; Brain Diseases; Catalase; Kainic Acid; Lipid Peroxidation; Male; Malondialdehyde; Melatonin | 2005 |
Neuroprotective effects of melatonin upon the offspring cerebellar cortex in the rat model of BCNU-induced cortical dysplasia.
Topics: Animals; Animals, Newborn; Brain Diseases; Bromodeoxyuridine; Carmustine; Cerebellar Cortex; Disease | 2007 |
Agomelatine, a melatonin receptor agonist with 5-HT(2C) receptor antagonist properties, protects the developing murine white matter against excitotoxicity.
Topics: Acetamides; Animals; Brain; Brain Diseases; Excitatory Amino Acid Agonists; Ibotenic Acid; Melatonin | 2008 |
[Epiphysis (pineal body) under normal and pathological conditions].
Topics: Brain Diseases; Humans; Melatonin; Pineal Gland | 1981 |
In vitro and in vivo protection against kainate-induced excitotoxicity by melatonin.
Topics: Animals; Ascorbic Acid; Brain; Brain Diseases; Dose-Response Relationship, Drug; Ferric Compounds; K | 1996 |
Hypogonadotrophic hypogonadism and primary amenorrhoea associated with increased melatonin secretion from a cystic pineal lesion.
Topics: Adolescent; Amenorrhea; Brain Diseases; Cysts; Female; Gonadotropins, Pituitary; Humans; Hypogonadis | 1996 |
Melatonin: clinical pharmacology.
Topics: Brain; Brain Diseases; Chemical Phenomena; Chemistry; Humans; Liver; Melatonin; Mental Disorders; Sl | 1978 |
[Cerebrospinal fluid melatonin in diseases of the nervous system].
Topics: Adolescent; Adult; Arachnoiditis; Brain Diseases; Brain Injuries; Brain Neoplasms; Epilepsy; Female; | 1977 |
Paraventricular nucleus-pineal interaction: relevance to tardive dyskinesia.
Topics: Animals; Antipsychotic Agents; Brain; Brain Diseases; Dyskinesia, Drug-Induced; Female; Humans; Male | 1992 |
SCN lesions block responses to systemic melatonin infusions in Siberian hamsters.
Topics: Animals; Body Weight; Brain Diseases; Circadian Rhythm; Cricetinae; Follicle Stimulating Hormone; In | 1991 |
Suprachiasmatic and paraventricular control of photoperiodism in Siberian hamsters.
Topics: Analysis of Variance; Animals; Arginine Vasopressin; beta-Endorphin; Body Weight; Brain Diseases; Ci | 1991 |
The relationship of pineal calcification to tardive dyskinesia.
Topics: Adult; Antipsychotic Agents; Brain Diseases; Calcinosis; Dyskinesia, Drug-Induced; Female; Humans; M | 1990 |
Factors influencing urinary 6-sulphatoxymelatonin, a major melatonin metabolite, in normal human subjects.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Body Height; Body Weight; Brain Diseases; C | 1990 |
Human melatonin in physiologic and diseased states: neural control of the rhythm.
Topics: Adult; Animals; Brain Diseases; Circadian Rhythm; Cricetinae; Humans; Hypothalamus; Light; Melatonin | 1986 |