melatonin has been researched along with Brain Concussion in 6 studies
Brain Concussion: A nonspecific term used to describe transient alterations or loss of consciousness following closed head injuries. The duration of UNCONSCIOUSNESS generally lasts a few seconds, but may persist for several hours. Concussions may be classified as mild, intermediate, and severe. Prolonged periods of unconsciousness (often defined as greater than 6 hours in duration) may be referred to as post-traumatic coma (COMA, POST-HEAD INJURY). (From Rowland, Merritt's Textbook of Neurology, 9th ed, p418)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Melatonin has significant neuroprotective properties, and promising preclinical data suggest its potential to improve outcomes after traumatic brain injury." | 2.94 | Efficacy of Melatonin in Children With Postconcussive Symptoms: A Randomized Clinical Trial. ( Barlow, KM; Boyd, R; Brooks, BL; Buchhalter, J; Cameron, C; Crawford, S; Dewey, D; Esser, MJ; Hill, MD; Hutchison, JS; Kirk, V; Kirton, A; MacMaster, FP; Mikrogianakis, A; Nettel-Aguirre, A; Platt, R; Richer, L; Samuel, T; Turley, B; Yeates, KO; Zemek, RL, 2020) |
| "Melatonin prescription was not associated with faster symptom recovery." | 1.62 | Sleep Problems and Melatonin Prescription After Concussion Among Youth Athletes. ( Howell, DR; Kirkwood, MW; Potter, MN; Provance, AJ; Wilson, JC; Wilson, PE, 2021) |
| "Melatonin was able to restore baseline function for control and enriched animals, but was ineffective for the stress condition." | 1.46 | Manipulating cognitive reserve: Pre-injury environmental conditions influence the severity of concussion symptomology, gene expression, and response to melatonin treatment in rats. ( Barlow, KM; Brooks, BL; Esser, MJ; Mychasiuk, R; Salberg, S; Yamakawa, GR; Yeates, KO, 2017) |
| "Evaluating sleep disorders following concussion is an important part of the assessment." | 1.46 | Sleep Disturbance Following Concussion Is a Risk Factor for a Prolonged Recovery. ( Bramley, H; Henson, A; Kong, L; Lewis, MM; Silvis, M; Stetter, C, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 4 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Korshnyak, VО | 1 |
| Pulyk, ОR | 1 |
| Stoyanov, ОM | 1 |
| Feinberg, C | 1 |
| Dickerson Mayes, K | 1 |
| Jarvis, RC | 1 |
| Carr, C | 1 |
| Mannix, R | 1 |
| Barlow, KM | 2 |
| Brooks, BL | 2 |
| Esser, MJ | 2 |
| Kirton, A | 1 |
| Mikrogianakis, A | 1 |
| Zemek, RL | 1 |
| MacMaster, FP | 1 |
| Nettel-Aguirre, A | 1 |
| Yeates, KO | 2 |
| Kirk, V | 1 |
| Hutchison, JS | 1 |
| Crawford, S | 1 |
| Turley, B | 1 |
| Cameron, C | 1 |
| Hill, MD | 1 |
| Samuel, T | 1 |
| Buchhalter, J | 1 |
| Richer, L | 1 |
| Platt, R | 1 |
| Boyd, R | 1 |
| Dewey, D | 1 |
| Howell, DR | 1 |
| Potter, MN | 1 |
| Provance, AJ | 1 |
| Wilson, PE | 1 |
| Kirkwood, MW | 1 |
| Wilson, JC | 1 |
| Yamakawa, GR | 1 |
| Salberg, S | 1 |
| Mychasiuk, R | 1 |
| Bramley, H | 1 |
| Henson, A | 1 |
| Lewis, MM | 1 |
| Kong, L | 1 |
| Stetter, C | 1 |
| Silvis, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| PLAY GAME: Post-concussion Syndrome Affecting Youth: GABAergic Effects of Melatonin. A Randomized Double-blind Placebo-controlled Trial of MELATONIN[NCT01874847] | Phase 2/Phase 3 | 99 participants (Actual) | Interventional | 2013-09-30 | Active, not recruiting | ||
| SurgerySMART: Studying Melatonin and Recovery in Teens[NCT06093477] | 40 participants (Anticipated) | Interventional | 2024-07-31 | Not yet recruiting | |||
| The Effectiveness of Melatonin for the Treatment of Acute Pediatric Concussion[NCT04731974] | Phase 2 | 254 participants (Anticipated) | Interventional | 2023-03-01 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for melatonin and Brain Concussion
| Article | Year |
|---|---|
Nutritional Supplement and Dietary Interventions as a Prophylaxis or Treatment of Sub-Concussive Repetitive Head Impact and Mild Traumatic Brain Injury: A Systematic Review.
Topics: Brain Concussion; Dietary Supplements; Humans; Melatonin; Observational Studies as Topic; Post-Concu | 2023 |
1 trial available for melatonin and Brain Concussion
| Article | Year |
|---|---|
Efficacy of Melatonin in Children With Postconcussive Symptoms: A Randomized Clinical Trial.
Topics: Adolescent; Brain Concussion; Child; Cognition; Confidence Intervals; Double-Blind Method; Female; H | 2020 |
Efficacy of Melatonin in Children With Postconcussive Symptoms: A Randomized Clinical Trial.
Topics: Adolescent; Brain Concussion; Child; Cognition; Confidence Intervals; Double-Blind Method; Female; H | 2020 |
Efficacy of Melatonin in Children With Postconcussive Symptoms: A Randomized Clinical Trial.
Topics: Adolescent; Brain Concussion; Child; Cognition; Confidence Intervals; Double-Blind Method; Female; H | 2020 |
Efficacy of Melatonin in Children With Postconcussive Symptoms: A Randomized Clinical Trial.
Topics: Adolescent; Brain Concussion; Child; Cognition; Confidence Intervals; Double-Blind Method; Female; H | 2020 |
Efficacy of Melatonin in Children With Postconcussive Symptoms: A Randomized Clinical Trial.
Topics: Adolescent; Brain Concussion; Child; Cognition; Confidence Intervals; Double-Blind Method; Female; H | 2020 |
Efficacy of Melatonin in Children With Postconcussive Symptoms: A Randomized Clinical Trial.
Topics: Adolescent; Brain Concussion; Child; Cognition; Confidence Intervals; Double-Blind Method; Female; H | 2020 |
Efficacy of Melatonin in Children With Postconcussive Symptoms: A Randomized Clinical Trial.
Topics: Adolescent; Brain Concussion; Child; Cognition; Confidence Intervals; Double-Blind Method; Female; H | 2020 |
Efficacy of Melatonin in Children With Postconcussive Symptoms: A Randomized Clinical Trial.
Topics: Adolescent; Brain Concussion; Child; Cognition; Confidence Intervals; Double-Blind Method; Female; H | 2020 |
Efficacy of Melatonin in Children With Postconcussive Symptoms: A Randomized Clinical Trial.
Topics: Adolescent; Brain Concussion; Child; Cognition; Confidence Intervals; Double-Blind Method; Female; H | 2020 |
4 other studies available for melatonin and Brain Concussion
| Article | Year |
|---|---|
REHABILITATION OF PATIENTS WITH LONG-TERM AFTEREFFECTS OF MILD COMBAT TRAUMATIC BRAIN INJURY.
Topics: Asthenia; Brain Concussion; Humans; Melatonin; Syndrome | 2022 |
Sleep Problems and Melatonin Prescription After Concussion Among Youth Athletes.
Topics: Adolescent; Athletes; Athletic Injuries; Brain Concussion; Child; Female; Humans; Male; Melatonin; P | 2021 |
Manipulating cognitive reserve: Pre-injury environmental conditions influence the severity of concussion symptomology, gene expression, and response to melatonin treatment in rats.
Topics: Animals; Antioxidants; Behavior, Animal; Brain Concussion; Cognitive Reserve; Environment; Epigenesi | 2017 |
Sleep Disturbance Following Concussion Is a Risk Factor for a Prolonged Recovery.
Topics: Adolescent; Brain Concussion; Central Nervous System Depressants; Female; Humans; Male; Melatonin; R | 2017 |