melatonin has been researched along with Bowel Diseases, Inflammatory in 15 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "to provide rationale for and develop treatment regimens using melatonin for inflammatory bowel diseases (IBD)." | 7.76 | [Use of melatonin in combined treatment for inflammatory bowel diseases]. ( Rakhimova, OIu, 2010) |
| "Melatonin has been confirmed to be useful in various diseases, including Alzheimer's disease, liver injuries and diseases, and cancers, while its role in IBDs remains unclear." | 5.62 | Melatonin reduces inflammation in intestinal cells, organoids and intestinal explants. ( Yuan, XQ; Zhang, XM, 2021) |
| "Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy." | 4.40 | Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023) |
| "Reduction of epigenetic target, EZH2 by melatonin significantly improves the clinical symptoms of dextran sodium sulphate induced colitis and may be implicated as a potential therapeutic target in IBD management." | 4.12 | Melatonin mediated inhibition of EZH2-NOS2 crosstalk attenuates inflammatory bowel disease in preclinical in vitro and in vivo models. ( Biswal, L; Choudhury, SR; Dev, A; Karmakar, S; Kushwaha, AC; Mohanbhai, SJ; Sardoiwala, MN; Sharma, SS, 2022) |
| "to provide rationale for and develop treatment regimens using melatonin for inflammatory bowel diseases (IBD)." | 3.76 | [Use of melatonin in combined treatment for inflammatory bowel diseases]. ( Rakhimova, OIu, 2010) |
| "Melatonin can enhance the intestinal mucosal barrier, alter the composition of intestinal bacteria in favor of bacteria with anti-inflammatory properties, regulate the immune response, alleviate inflammation and attenuate oxidative stress." | 3.01 | Melatonin and inflammatory bowel disease: From basic mechanisms to clinical application. ( Alemi, F; Alipourian, A; Khazaie, S; Malakoti, F; Moein, S; Qujeq, D; Vaghari-Tabari, M; Yousefi, B, 2023) |
| "Melatonin has been shown as a specific antioxidant reducing oxidative damage in both lipid and aqueous cell environments." | 2.47 | New paradigms in chronic intestinal inflammation and colon cancer: role of melatonin. ( García-Mauriño, S; Illanes, M; Motilva, V; Talero, E, 2011) |
| "Melatonin has emerged as a potent anti-inflammatory agent." | 1.72 | Colon targeted chitosan-melatonin nanotherapy for preclinical Inflammatory Bowel Disease. ( Choudhury, SR; Guchhait, P; Gupta, S; Karmakar, S; Mohanbhai, SJ; Sardoiwala, MN; Sharma, SS; Shrimali, N, 2022) |
| "Melatonin has emerged as a potent anti-inflammatory and neuroprotective candidate." | 1.62 | Melatonin-loaded chitosan nanoparticles endows nitric oxide synthase 2 mediated anti-inflammatory activity in inflammatory bowel disease model. ( Choudhury, SR; Karmakar, S; Sardoiwala, MN; Sharma, SS; Soni, JM, 2021) |
| "Melatonin has been confirmed to be useful in various diseases, including Alzheimer's disease, liver injuries and diseases, and cancers, while its role in IBDs remains unclear." | 1.62 | Melatonin reduces inflammation in intestinal cells, organoids and intestinal explants. ( Yuan, XQ; Zhang, XM, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (53.33) | 24.3611 |
| 2020's | 7 (46.67) | 2.80 |
| Authors | Studies |
|---|---|
| Sardoiwala, MN | 3 |
| Mohanbhai, SJ | 2 |
| Kushwaha, AC | 1 |
| Dev, A | 1 |
| Biswal, L | 1 |
| Sharma, SS | 3 |
| Choudhury, SR | 3 |
| Karmakar, S | 3 |
| Gupta, S | 1 |
| Shrimali, N | 1 |
| Guchhait, P | 1 |
| Vaghari-Tabari, M | 1 |
| Moein, S | 1 |
| Alipourian, A | 1 |
| Qujeq, D | 1 |
| Malakoti, F | 1 |
| Alemi, F | 1 |
| Yousefi, B | 1 |
| Khazaie, S | 1 |
| Conley, S | 1 |
| Proctor, DD | 1 |
| Lehner, V | 1 |
| Jeon, S | 1 |
| Redeker, NS | 1 |
| Soni, JM | 1 |
| Yuan, XQ | 1 |
| Zhang, XM | 1 |
| Talero, E | 2 |
| Garcia-Maurino, S | 2 |
| Motilva, V | 2 |
| Takagi, T | 1 |
| Inada, Y | 1 |
| Naito, Y | 1 |
| Parekh, PJ | 1 |
| Oldfield Iv, EC | 1 |
| Challapallisri, V | 1 |
| Ware, JC | 1 |
| Johnson, DA | 1 |
| Burgess, HJ | 2 |
| Swanson, GR | 2 |
| Keshavarzian, A | 2 |
| Rakhimova, OIu | 1 |
| Illanes, M | 1 |
| Mozaffari, S | 1 |
| Abdollahi, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Circadian Misalignment as a Disease Risk Factor in Inflammatory Bowel Disease[NCT04637399] | 52 participants (Actual) | Observational | 2016-11-22 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for melatonin and Bowel Diseases, Inflammatory
| Article | Year |
|---|---|
Melatonin and inflammatory bowel disease: From basic mechanisms to clinical application.
Topics: Animals; Bacteria; Inflammation; Inflammatory Bowel Diseases; Intestinal Mucosa; Intestines; Melaton | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Melatonin, autophagy and intestinal bowel disease.
Topics: Autophagy; Humans; Immunity, Innate; Inflammatory Bowel Diseases; Melatonin | 2014 |
[Circadian rhythm and inflammatory bowel disease].
Topics: Animals; Chronotherapy; Circadian Rhythm; Disease Models, Animal; Humans; Inflammatory Bowel Disease | 2013 |
Sleep disturbances and inflammatory bowel disease: a potential trigger for disease flare?
Topics: Animals; Circadian Clocks; Circadian Rhythm; Colitis, Ulcerative; Crohn Disease; Humans; Inflammator | 2011 |
New paradigms in chronic intestinal inflammation and colon cancer: role of melatonin.
Topics: Animals; Autophagy; Chronic Disease; Colonic Neoplasms; Humans; Inflammatory Bowel Diseases; Melaton | 2011 |
Melatonin, a promising supplement in inflammatory bowel disease: a comprehensive review of evidences.
Topics: Animals; Clinical Trials as Topic; Dietary Supplements; Drug Evaluation, Preclinical; Free Radical S | 2011 |
1 trial available for melatonin and Bowel Diseases, Inflammatory
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
8 other studies available for melatonin and Bowel Diseases, Inflammatory
| Article | Year |
|---|---|
Melatonin mediated inhibition of EZH2-NOS2 crosstalk attenuates inflammatory bowel disease in preclinical in vitro and in vivo models.
Topics: Animals; Colitis; Dextran Sulfate; Dextrans; Disease Models, Animal; Enhancer of Zeste Homolog 2 Pro | 2022 |
Colon targeted chitosan-melatonin nanotherapy for preclinical Inflammatory Bowel Disease.
Topics: Animals; Anti-Inflammatory Agents; Chitosan; Colitis, Ulcerative; Inflammatory Bowel Diseases; Melat | 2022 |
The Feasibility of Measuring Sleep and Circadian Characteristics in Adults with Inflammatory Bowel Disease.
Topics: Actigraphy; Adult; Circadian Rhythm; Diaries as Topic; Feasibility Studies; Female; Humans; Inflamma | 2020 |
Melatonin-loaded chitosan nanoparticles endows nitric oxide synthase 2 mediated anti-inflammatory activity in inflammatory bowel disease model.
Topics: Anti-Inflammatory Agents; Chitosan; Humans; Inflammatory Bowel Diseases; Melatonin; Nanoparticles; N | 2021 |
Melatonin reduces inflammation in intestinal cells, organoids and intestinal explants.
Topics: Caco-2 Cells; Cytokines; Gene Silencing; Humans; Inflammation; Inflammatory Bowel Diseases; Intestin | 2021 |
Sleep disorders and inflammatory disease activity: chicken or the egg?
Topics: Animals; C-Reactive Protein; Circadian Rhythm; Clinical Trials as Topic; Colitis, Ulcerative; Crohn | 2015 |
Endogenous melatonin profiles in asymptomatic inflammatory bowel disease.
Topics: Adult; Biomarkers; Circadian Rhythm; Female; Humans; Inflammatory Bowel Diseases; Male; Melatonin; S | 2010 |
[Use of melatonin in combined treatment for inflammatory bowel diseases].
Topics: Adult; Anti-Inflammatory Agents; Antioxidants; Biopsy; Dose-Response Relationship, Drug; Drug Therap | 2010 |