melatonin has been researched along with Body Weight in 469 studies
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We aimed to evaluate melatonin effectiveness in weight gain reduction following olanzapine use for 11-17-year-old bipolar disorder patients." | 9.24 | Melatonin for Reducing Weight Gain Following Administration of Atypical Antipsychotic Olanzapine for Adolescents with Bipolar Disorder: A Randomized, Double-Blind, Placebo-Controlled Trial. ( Akhondzadeh, S; Mohammadi, MR; Mostafavi, SA; Solhi, M, 2017) |
| "The aim of the present work was to determine whether treatment with melatonin modifies the reproductive response of female goats experiencing increasing or decreasing body weight (BW)/body condition score (BCS) when introduced to bucks displaying springtime sexual activity." | 9.24 | The reproductive performance of female goats treated with melatonin is not improved after introduction to bucks displaying springtime sexual activity if these does are experiencing decreasing body weight/condition score. ( Gallego-Calvo, L; Gatica, MC; Guzmán, JL; Zarazaga, LA, 2017) |
| "Prior studies have suggested that melatonin, a frequently used integrative medicine, can attenuate weight loss, anorexia, and fatigue in patients with cancer." | 9.17 | Effects of melatonin on appetite and other symptoms in patients with advanced cancer and cachexia: a double-blind placebo-controlled trial. ( Bruera, E; Del Fabbro, E; Dev, R; Hui, D; Palmer, L, 2013) |
| "The effect of fish oil (FO), melatonin (MLT), or their combination and dietary advice on cachexia and biochemistry variables reflecting cachexia were investigated in patients with advanced gastrointestinal cancer." | 9.11 | Impact of fish oil and melatonin on cachexia in patients with advanced gastrointestinal cancer: a randomized pilot study. ( Glimelius, B; Nygren, P; Persson, C; Rönnelid, J, 2005) |
| "In order to test the efficacy of the pineal neurohumor melatonin on depression, the hormone was administered in varying doses to six moderately to severely depressed patients and two patients with Huntington's chorea in double-blind crossover study." | 9.04 | Negative effects of melatonin on depression. ( Buswell, R; Carman, JS; Goodwin, FK; Post, RM, 1976) |
| "Some trials on animals and human claim that melatonin can influence body weight." | 8.95 | Role of Melatonin in Body Weight: A Systematic Review and Meta-Analysis. ( Akhondzadeh, S; Alipour, R; Eshraghian, MR; Hosseini, S; Keshavarz, SA; Keshtkar, AA; Mohammadi, MR; Mostafavi, SA; Motlagh, TA, 2017) |
| "This study investigated the protective effects of melatonin (MT) against cisplatin (CP)-induced acute kidney injury in rats as well as its possible mechanism of action associated with anti-aging protein Klotho." | 7.91 | Melatonin attenuates cisplatin-induced acute kidney injury in rats via induction of anti-aging protein, Klotho. ( Jung, TY; Kim, HC; Kim, JC; Kim, SH; Ko, JW; Lee, IC; Moon, C; Shin, IS; Shin, NR; Yun, WK, 2019) |
| "When the sexual activity of bucks is minimal, there is a minimal male effect on does regardless of their body weight (BW)/body condition (BC) and whether does are treated with melatonin or not." | 7.88 | Reproductive responses to sexually active buck of does treated with melatonin when body weight/body condition is increasing or decreasing. ( Gallego-Calvo, L; Gatica, MC; Guzmán, JL; Zarazaga, LA, 2018) |
| " This study explored the hypothesis that melatonin has beneficial functions in the mouse model of colitis induced by dextran sodium sulfate (DSS), with a specific focus on the expression of intestinal inflammatory cytokines and the serum levels of amino acids." | 7.85 | Melatonin alters amino acid metabolism and inflammatory responses in colitis mice. ( Chen, S; Fang, J; Jiang, Q; Liu, G; Ren, W; Yao, K; Yin, J; Yin, Y, 2017) |
| "The present study was aimed at evaluating the rapidity and duration of melatonin as an antidepressant in a rat model of depression." | 7.85 | Melatonin produces a rapid onset and prolonged efficacy in reducing depression-like behaviors in adult rats exposed to chronic unpredictable mild stress. ( Li, Q; Lian, B; Sun, H; Sun, L; Sun, X; Wang, G; Wang, M; Wang, Y, 2017) |
| "To determine adiponectin expression in colonic tissue of murine colitis and systemic cytokine expression after melatonin treatments and sleep deprivation." | 7.83 | Melatonin modulates adiponectin expression on murine colitis with sleep deprivation. ( Baik, HW; Choi, JW; Chung, SH; Gye, MC; Jun, JH; Kim, EK; Kim, JB; Kim, SH; Kim, TK; Lim, JY; Park, YS; Sull, JW; Sung, HJ, 2016) |
| " Melatonin is a sleep-related neurohormone, also known to have antioxidant and anti-inflammatory effects in the gastrointestinal tract; however, the effects of melatonin on colitis have been poorly characterized." | 7.81 | Melatonin improves experimental colitis with sleep deprivation. ( Baik, HW; Chung, SH; Kim, DS; Kim, JB; Kim, JH; Kim, TK; Lee, SK; Park, YS, 2015) |
| "The present results suggest that melatonin prevents the well-recognized increase in glucose levels that usually follows exposure to intermittent hypoxia." | 7.81 | Melatonin prevents hyperglycemia in a model of sleep apnea. ( Fagundes, M; Fiori, CZ; Kaminski, RS; Marroni, NP; Martinez, D; Martins, EF; Montanari, CC; Rosa, DP, 2015) |
| " Sleep deprivation aggravated, and melatonin attenuated the severity of colitis." | 7.80 | Melatonin attenuates dextran sodium sulfate induced colitis with sleep deprivation: possible mechanism by microarray analysis. ( Ahn, SB; Baik, HW; Chung, SH; Hong, YO; Jo, Y; Jo, YK; Jun, JH; Kim, JH; Kim, OS; Kim, SH; Kim, SS; Park, YS; Shin, JH; Son, BK, 2014) |
| "This study aimed to investigate the potential protective effects of melatonin (Mel) against aluminium-induced neurodegenerative changes in aging Wistar rats (24-28months old)." | 7.80 | Effects of melatonin on aluminium-induced neurobehavioral and neurochemical changes in aging rats. ( Allagui, MS; Badraoui, R; Bouoni, Z; Elfeki, A; Feriani, A; Murat, JC; Nciri, R; Saoudi, M, 2014) |
| "Chronic melatonin treatment has been shown to prevent the harmful effects of diet-induced obesity and reduce myocardial susceptibility to ischaemia-reperfusion injury (IRI)." | 7.80 | Short-term melatonin consumption protects the heart of obese rats independent of body weight change and visceral adiposity. ( Blackhurst, D; Huisamen, B; Lochner, A; Nduhirabandi, F; Strijdom, H, 2014) |
| "Although melatonin supplementation is known to influence numerous physiological functions, little is however known of its effects on pregnancy outcome." | 7.79 | Effect of melatonin supplementation on pregnancy outcome in Wistar-Kyoto and Sprague-Dawley rats. ( Gupalo, S; Omar, E; Saleh, HI; Singh, HJ, 2013) |
| "In this study, we examined whether melatonin improves metabolic syndrome induced by high fructose intake in male Wistar rats." | 7.78 | Melatonin improves metabolic syndrome induced by high fructose intake in rats. ( Kitagawa, A; Ohashi, K; Ohta, Y, 2012) |
| " Animals were then tested for reward-seeking behaviour (saccharin consumption), anxiety (elevated plus-maze), aggression (resident-intruder test), and depression-like behaviour (FST)." | 7.75 | We are in the dark here: induction of depression- and anxiety-like behaviours in the diurnal fat sand rat, by short daylight or melatonin injections. ( Ashkenazy, T; Einat, H; Kronfeld-Schor, N, 2009) |
| " The aim of this study was to investigate the protective effects in rat maternal and fetal livers as also the placenta of melatonin or silymarin against the oxidative stress and apoptosis induced by maternal obstructive cholestasis during the last third of pregnancy (OCP)." | 7.74 | Multiple protective effects of melatonin against maternal cholestasis-induced oxidative stress and apoptosis in the rat fetal liver-placenta-maternal liver trio. ( Castaño, B; Gonzalez-Buitrago, JM; Marin, JJ; Perez, MJ, 2007) |
| "The study in ovariectomized (Ovx) rats, as a model of menopausal status, of the effects of melatonin (M) and/or estradiol (E), associated or not with food restriction, on body weight (BW) and serum leptin levels." | 7.74 | Melatonin and estradiol effects on food intake, body weight, and leptin in ovariectomized rats. ( Alonso-Gonzalez, C; Cos, S; Gonzalez, A; Martinez-Campa, CM; Mediavilla, MD; Sanchez-Barcelo, EJ; Sanchez-Mateos, S, 2007) |
| "Melatonin secretion decreased in fructose fed rats that developed hypertension." | 7.74 | The role of melatonin in the pathogenesis of hypertension in rats with metabolic syndrome. ( Grossman, E; Leibowitz, A; Peleg, E; Shabtai, Z; Shamiss, A; Sharabi, Y, 2008) |
| "Both plasma melatonin levels and hypothalamic arcuate nucleus pro-opiomelanocortin (POMC) (biosynthetic precursor to the endogenous opioid ss-endorphin and other opiomelanocortins) mRNA content decrease with aging." | 7.72 | Suppression of hypothalamic pro-opiomelanocortin (POMC) gene expression by daily melatonin supplementation in aging rats. ( Boldt, BM; Marck, BT; Matsumoto, AM; Rasmussen, DD; Yellon, SM, 2003) |
| "To determine whether suppression of melatonin secretion without surgery in chickens can result in scoliosis development." | 7.72 | Effect of melatonin suppression on scoliosis development in chickens by either constant light or surgical pinealectomy. ( Cheung, KM; Leong, JC; Lu, DS; Luk, KD; Poon, AM; Wang, T, 2003) |
| "The aim of this study was to investigate structural changes that occurred in the skeletal muscle of rats with experimental hyperthyroidism and the effect of melatonin on these changes." | 7.72 | Effects of melatonin on skeletal muscle of rats with experimental hyperthyroidism. ( Oner, J; Ozan, E, 2003) |
| "The aim of the present study was to test the hypothesis that the natural antioxidant melatonin (MEL) and the synthetic antioxidant stobadine (STO) could reduce the incidence of maternal and embryofoetal toxicity in rats due to intrauterine hypoxia." | 7.72 | Effect of melatonin and stobadine on maternal and embryofoetal toxicity in rats due to intrauterine hypoxia induced by phenytoin administration. ( Brucknerová, I; Dubovický, M; Juránek, I; Mach, M; Navarová, J; Soltés, L; Ujházy, E; Zeman, M, 2004) |
| "It is generally accepted that antioxidant properties of melatonin significantly contribute to its antiaging effect." | 7.71 | Antioxidant and antiaging activity of N-acetylserotonin and melatonin in the in vivo models. ( Bachurin, S; Oxenkrug, G; Requintina, P, 2001) |
| " To assess the effect of aging and accelerated aging on the circadian pacemaker of this primate, we measured body weight variations, the daily rhythm in urine 6-sulfatoxymelatonin and the light-induced expression of the immediate early gene (Fos) in the suprachiasmatic nucleus of mouse lemurs that had been exposed to different photoperiodic cycles." | 7.71 | Artificially accelerated aging by shortened photoperiod alters early gene expression (Fos) in the suprachiasmatic nucleus and sulfatoxymelatonin excretion in a small primate, Microcebus murinus. ( Aujard, F; Claustrat, B; Cooper, HM; Dkhissi-Benyahya, O; Fournier, I; Perret, M; Schilling, A, 2001) |
| "Plasma melatonin levels were measured at three-hourly intervals over 24 hours in 11 women with untreated anorexia nervosa, and in nine healthy women of normal weight." | 7.68 | Plasma melatonin levels in anorexia nervosa. ( Arendt, J; Bhanji, S; Franey, C; Mattingly, D, 1992) |
| "To investigate whether the function of pinealocytes is altered in obesity, nocturnal melatonin (MT) secretion was determined in nine healthy subjects and compared with that of eight obese individuals." | 7.68 | Effect of short-term fasting on nocturnal melatonin secretion in obesity. ( Röjdmark, S; Rössner, S; Wetterberg, L, 1992) |
| "This study examined whether melatonin-induced inhibition of testicular weight and body weight in vivo could be antagonized by luzindole, a competitive melatonin receptor antagonist, or methysergide, a competitive serotonin receptor antagonist." | 7.68 | Effects of melatonin agonists and antagonists on reproduction and body weight in the Siberian hamster. ( Dubocovich, ML; Duncan, MJ; Fang, JM, 1990) |
| "Two experiments examined the effects of photoperiod, melatonin, and diet on body weight in female Syrian hamsters (Mesocricetus auratus)." | 7.67 | Seasonal obesity in Syrian hamsters: effects of age, diet, photoperiod, and melatonin. ( Bartness, TJ; Wade, GN, 1984) |
| "The effects of photoperiod and the pineal hormone melatonin on the regulation of body weight and energy metabolism were examined in Syrian hamsters, Mesocricetus auratus." | 7.67 | Photoperiodic control of body weight and energy metabolism in Syrian hamsters (Mesocricetus auratus): role of pineal gland, melatonin, gonads, and diet. ( Bartness, TJ; Wade, GN, 1984) |
| "To clarify a controversy as to whether melatonin secretion is related to body weight, urinary sulphatoxymelatonin (aMT6s) excretion was estimated in 10 patients with anorexia nervosa before and after weight gain, and compared with 10 age-matched controls." | 7.67 | A study of sulphatoxymelatonin excretion and gonadotrophin status during weight gain in anorexia nervosa. ( Arendt, J; Bearn, J; Checkley, SA; Franey, C; Murphy, M; Treasure, J; Wheeler, M, 1988) |
| "The effects of the pineal indole melatonin on a transplantable androgen-insensitive fast-growing rat prostatic adenocarcinoma, the Dunning R 3327 HIF tumor, were examined." | 7.67 | Studies on the effects of the pineal hormone melatonin on an androgen-insensitive rat prostatic adenocarcinoma, the Dunning R 3327 HIF tumor. ( Buzzell, GR, 1988) |
| "The mean 24-hour secretion and circadian rhythm of melatonin were studied in 12 female subjects with anorexia nervosa (AN), 13 massively obese (OB) women, and 9 normal weight healthy volunteers to investigate the relationship between type of feeding behavior and hormonal secretory pattern." | 7.67 | Melatonin circadian rhythm in anorexia nervosa and obesity. ( Bossolo, PA; Brambilla, F; Esposti, G; Ferrari, E; Fraschini, F; Marelli, G, 1988) |
| "Four doses of melatonin were administered intramuscularly over 30 days in separate groups of intact adult male Lal munia, Estrilda amandava, during mid-day (1300 hr) and mid-night (0100 hr) in separate sets during the month of August (late progressive phase), and their effects were studied on the body weight, gonadal and thyroidal activities, and luteinizing hormone (LH)-dependent plumage and beak pigmentation." | 7.67 | Effect of melatonin on gonads, body weight, and luteinizing hormone (LH) dependent coloration of the Indian finch, Lal munia (Estrilda amandava). ( Ghosh, M; Gupta, BB; Haldar-Misra, C; Thapliyal, JP, 1987) |
| " Half of the hamsters were injected with melatonin in a schedule that mimics the effects of short photoperiods by decreasing body weight, carcass lipid content, and testis weight." | 7.67 | Body weight, food intake and energy regulation in exercising and melatonin-treated Siberian hamsters. ( Bartness, TJ; Wade, GN, 1985) |
| "Melatonin has been shown to have beneficial effects in cardiovascular disorders including ischaemic heart disease and hypertension." | 6.48 | Melatonin and the metabolic syndrome: a tool for effective therapy in obesity-associated abnormalities? ( du Toit, EF; Lochner, A; Nduhirabandi, F, 2012) |
| "Melatonin is a sleep-related neurohormone and affected by the circadian rhythm and light/dark cycles." | 5.72 | Melatonin protects against body weight gain induced by sleep deprivation in mice. ( Hu, S; Liu, X; Wang, Y; Wei, S; Zhang, R, 2022) |
| "Melatonin plays an important role in the thermoregulatory mechanisms, ensuring greater capacity to withstand cold and, also, participating in the regulation of energy balance." | 5.62 | The effects of melatonin daily supplementation to aged rats on the ability to withstand cold, thermoregulation and body weight. ( Amaral, FG; Belpiede, LT; Cipolla-Neto, J; do Carmo Buonfiglio, D; Gomes, G; Mendes, C; Motta-Teixeira, LC, 2021) |
| "Leptin is an adipokine secreted in a manner dependent on the circadian rhythm that ultimately reduces food intake." | 5.48 | Melatonin Prevents the Harmful Effects of Obesity on the Brain, Including at the Behavioral Level. ( Bermejo-Millo, JC; Boga, JA; Caballero, B; Coto-Montes, A; de Luxán-Delgado, B; Pérez-Martínez, Z; Potes, Y; Rubio-González, A; Solano, JJ; Vega-Naredo, I, 2018) |
| "Fibromyalgia is a chronic syndrome characterized by widespread musculoskeletal pain and an extensive array of other symptoms including disordered sleep, fatigue, depression and anxiety." | 5.46 | Oral Supplementation of Melatonin Protects against Fibromyalgia-Related Skeletal Muscle Alterations in Reserpine-Induced Myalgia Rats. ( Bonomini, F; Favero, G; Lavazza, A; Rezzani, R; Rodella, LF; Stacchiotti, A; Trapletti, V, 2017) |
| "Melatonin can reduce damage to male rodents' gonadal tissue and improve sperm count, motility, and morphology in metabolic diseases." | 5.41 | Protective effects of melatonin against oxidative stress induced by metabolic disorders in the male reproductive system: a systematic review and meta-analysis of rodent models. ( Ala, M; Azarpira, N; Dehdari Ebrahimi, N; Ebrahimi, F; Pakbaz, S; Sadeghi, A, 2023) |
| " According to our meta-analysis, all outcomes were significantly improved by melatonin therapy, including sperm quantity and quality (count, motility, viability, normal morphology, number of spermatogonia, Johnsen's testicular biopsy score, seminiferous tubular diameter, and seminiferous epithelial height), serum level of reproductive hormones (Follicle-Stimulating Hormone and testosterone), tissue markers of oxidative stress (testicular tissue malondialdehyde, superoxide dismutase, glutathione peroxidase, catalase, glutathione, caspase-3, and total antioxidant capacity), and weight-related characteristics (absolute body, epididymis, testis, and relative testis to body weights)." | 5.41 | Protective effects of exogenous melatonin therapy against oxidative stress to male reproductive tissue caused by anti-cancer chemical and radiation therapy: a systematic review and meta-analysis of animal studies. ( Azarpira, N; Dehdari Ebrahimi, N; Eghlidos, Z; Rahimian, Z; Sadeghi, A; Safarpour, AR; Shahlaee, MA; Shojaei-Zarghani, S; Taherifard, E, 2023) |
| " This study is aimed at determining the effects of melatonin supplementation on body weight, nody mass index (BMI), waist circumference (WC), and body fat mass percentage (BFMP) in people with overweight or obesity." | 5.41 | Melatonin Supplementation and Anthropometric Indices: A Randomized Double-Blind Controlled Clinical Trial. ( Amiri, Z; Djafarian, K; Ghaffarian-Bahraman, A; Hassanipour, S; Jahangir, F; Mohammadi, S; Mohsenpour, MA; Rastmanesh, R, 2021) |
| "Melatonin was administered in drinking water at the dose of 0." | 5.40 | Melatonin prevents neonatal dexamethasone induced programmed hypertension: histone deacetylase inhibition. ( Chien, SJ; Huang, LT; Kuo, HC; Lin, IC; Tain, YL; Wu, TH, 2014) |
| "Melatonin-treated rats received 0." | 5.36 | Melatonin prevents hypertension and increased asymmetric dimethylarginine in young spontaneous hypertensive rats. ( Huang, LT; Lau, YT; Lin, CY; Lin, IC; Tain, YL, 2010) |
| "Melatonin was administered as an antioxidant." | 5.32 | Melatonin reduces renal interstitial inflammation and improves hypertension in spontaneously hypertensive rats. ( Nava, M; Quiroz, Y; Rodriguez-Iturbe, B; Vaziri, N, 2003) |
| "Melatonin-treated rats that were then crossed over to control treatment for a further 12 weeks gained BW, whereas control rats that were crossed to melatonin treatment lost BW, but food intake did not change in either group." | 5.31 | Daily melatonin administration to middle-aged male rats suppresses body weight, intraabdominal adiposity, and plasma leptin and insulin independent of food intake and total body fat. ( Matsumoto, AM; McCants, RL; Mitton, DR; Rasmussen, DD; Wilkinson, CW; Wolden-Hanson, T; Yellon, SM, 2000) |
| "Fever is considered an important host defense response but requires significant metabolic energy." | 5.31 | Melatonin regulates energy balance and attenuates fever in Siberian hamsters. ( Bilbo, SD; Nelson, RJ, 2002) |
| "As melatonin levels have been reported to decrease with age, melatonin replacement therapy may attenuate the incidence of sudden cardiac death especially in older patients." | 5.31 | Effects of physiological and pharmacological concentrations of melatonin on ischemia-reperfusion arrhythmias in rats: can the incidence of sudden cardiac death be reduced? ( Acet, A; Olmez, E; Sahna, E, 2002) |
| "Melatonin-treated mice received either short-term treatment on Days 1 and 2 after hemorrhage or continuous treatment throughout the study." | 5.29 | Melatonin administration following hemorrhagic shock decreases mortality from subsequent septic challenge. ( Ayala, A; Chaudry, IH; Haisken, JM; Wichmann, MW, 1996) |
| "Melatonin in tissues was extracted, identified, and determined by gas chromatography-mass spectrometry (GC-MS) and/or radioimmunoassay." | 5.28 | Fluctuation of blood melatonin concentrations with age: result of changes in pineal melatonin secretion, body growth, and aging. ( Brown, GM; Hong, GX; Pang, SF; Tang, PL; Tsang, CW; Yip, PC, 1990) |
| "Melatonin-treated hamsters had significantly greater mean body weights than did the vehicle-treated hamsters (P less than 0." | 5.28 | Effects of daily afternoon melatonin administration on body weight and thyroid hormones in female hamsters. ( Petterborg, LJ; Rudeen, PK, 1989) |
| "Melatonin was estimated by RIA in samples taken at 24." | 5.26 | Reduced nocturnal melatonin secretion in chronic schizophrenia: relationship to body weight. ( Arendt, J; Crow, TJ; Ferrier, IN; Johnstone, EC, 1982) |
| "Melatonin treatment prevented the atrophic responses of the testes and accessory sex organs in males and the uteri in females." | 5.26 | Prevention by melatonin of short day induced atrophy of the reproductive systems of male and female hamsters. ( Reiter, RJ; Vaughan, MK; Waring, PJ, 1977) |
| "We aimed to evaluate melatonin effectiveness in weight gain reduction following olanzapine use for 11-17-year-old bipolar disorder patients." | 5.24 | Melatonin for Reducing Weight Gain Following Administration of Atypical Antipsychotic Olanzapine for Adolescents with Bipolar Disorder: A Randomized, Double-Blind, Placebo-Controlled Trial. ( Akhondzadeh, S; Mohammadi, MR; Mostafavi, SA; Solhi, M, 2017) |
| "Prior studies have suggested that melatonin, a frequently used integrative medicine, can attenuate weight loss, anorexia, and fatigue in patients with cancer." | 5.17 | Effects of melatonin on appetite and other symptoms in patients with advanced cancer and cachexia: a double-blind placebo-controlled trial. ( Bruera, E; Del Fabbro, E; Dev, R; Hui, D; Palmer, L, 2013) |
| "The effect of fish oil (FO), melatonin (MLT), or their combination and dietary advice on cachexia and biochemistry variables reflecting cachexia were investigated in patients with advanced gastrointestinal cancer." | 5.11 | Impact of fish oil and melatonin on cachexia in patients with advanced gastrointestinal cancer: a randomized pilot study. ( Glimelius, B; Nygren, P; Persson, C; Rönnelid, J, 2005) |
| "In order to test the efficacy of the pineal neurohumor melatonin on depression, the hormone was administered in varying doses to six moderately to severely depressed patients and two patients with Huntington's chorea in double-blind crossover study." | 5.04 | Negative effects of melatonin on depression. ( Buswell, R; Carman, JS; Goodwin, FK; Post, RM, 1976) |
| "High circulating concentrations of leptin in obesity are associated with an apparent loss of its characteristic anorexic action within the hypothalamic region of the brain." | 4.82 | Appetite regulation and seasonality: implications for obesity. ( Adam, CL; Mercer, JG, 2004) |
| " The systems involved regulate body weight around an apparent 'set-point' through the action of photoperiod via the neurohormone, melatonin." | 4.81 | The regulation of body weight: lessons from the seasonal animal. ( Mercer, JG; Morgan, PJ, 2001) |
| "Findings will provide timely information on the safety, efficacy, and optimal dosing of t-PA to treat moderate/severe COVID-19-induced ARDS, which can be rapidly adapted to a phase III trial (NCT04357730; FDA IND 149634)." | 4.21 | ( Abbasi, S; Abd El-Wahab, A; Abdallah, M; Abebe, G; Aca-Aca, G; Adama, S; Adefegha, SA; Adidigue-Ndiome, R; Adiseshaiah, P; Adrario, E; Aghajanian, C; Agnese, W; Ahmad, A; Ahmad, I; Ahmed, MFE; Akcay, OF; Akinmoladun, AC; Akutagawa, T; Alakavuklar, MA; Álava-Rabasa, S; Albaladejo-Florín, MJ; Alexandra, AJE; Alfawares, R; Alferiev, IS; Alghamdi, HS; Ali, I; Allard, B; Allen, JD; Almada, E; Alobaid, A; Alonso, GL; Alqahtani, YS; Alqarawi, W; Alsaleh, H; Alyami, BA; Amaral, BPD; Amaro, JT; Amin, SAW; Amodio, E; Amoo, ZA; Andia Biraro, I; Angiolella, L; Anheyer, D; Anlay, DZ; Annex, BH; Antonio-Aguirre, B; Apple, S; Arbuznikov, AV; Arinsoy, T; Armstrong, DK; Ash, S; Aslam, M; Asrie, F; Astur, DC; Atzrodt, J; Au, DW; Aucoin, M; Auerbach, EJ; Azarian, S; Ba, D; Bai, Z; Baisch, PRM; Balkissou, AD; Baltzopoulos, V; Banaszewski, M; Banerjee, S; Bao, Y; Baradwan, A; Barandika, JF; Barger, PM; Barion, MRL; Barrett, CD; Basudan, AM; Baur, LE; Baz-Rodríguez, SA; Beamer, P; Beaulant, A; Becker, DF; Beckers, C; Bedel, J; Bedlack, R; Bermúdez de Castro, JM; Berry, JD; Berthier, C; Bhattacharya, D; Biadgo, B; Bianco, G; Bianco, M; Bibi, S; Bigliardi, AP; Billheimer, D; Birnie, DH; Biswas, K; Blair, HC; Bognetti, P; Bolan, PJ; Bolla, JR; Bolze, A; Bonnaillie, P; Borlimi, R; Bórquez, J; Bottari, NB; Boulleys-Nana, JR; Brighetti, G; Brodeur, GM; Budnyak, T; Budnyk, S; Bukirwa, VD; Bulman, DM; Burm, R; Busman-Sahay, K; Butcher, TW; Cai, C; Cai, H; Cai, L; Cairati, M; Calvano, CD; Camacho-Ordóñez, A; Camela, E; Cameron, T; Campbell, BS; Cansian, RL; Cao, Y; Caporale, AS; Carciofi, AC; Cardozo, V; Carè, J; Carlos, AF; Carozza, R; Carroll, CJW; Carsetti, A; Carubelli, V; Casarotta, E; Casas, M; Caselli, G; Castillo-Lora, J; Cataldi, TRI; Cavalcante, ELB; Cavaleiro, A; Cayci, Z; Cebrián-Tarancón, C; Cedrone, E; Cella, D; Cereda, C; Ceretti, A; Ceroni, M; Cha, YH; Chai, X; Chang, EF; Chang, TS; Chanteux, H; Chao, M; Chaplin, BP; Chaturvedi, S; Chaturvedi, V; Chaudhary, DK; Chen, A; Chen, C; Chen, HY; Chen, J; Chen, JJ; Chen, K; Chen, L; Chen, Q; Chen, R; Chen, SY; Chen, TY; Chen, WM; Chen, X; Chen, Y; Cheng, G; Cheng, GJ; Cheng, J; Cheng, YH; Cheon, HG; Chew, KW; Chhoker, S; Chiu, WN; Choi, ES; Choi, MJ; Choi, SD; Chokshi, S; Chorny, M; Chu, KI; Chu, WJ; Church, AL; Cirrincione, A; Clamp, AR; Cleff, MB; Cohen, M; Coleman, RL; Collins, SL; Colombo, N; Conduit, N; Cong, WL; Connelly, MA; Connor, J; Cooley, K; Correa Ramos Leal, I; Cose, S; Costantino, C; Cottrell, M; Cui, L; Cundall, J; Cutaia, C; Cutler, CW; Cuypers, ML; da Silva Júnior, FMR; Dahal, RH; Damiani, E; Damtie, D; Dan-Li, W; Dang, Z; Dasa, SSK; Davin, A; Davis, DR; de Andrade, CM; de Jong, PL; de Oliveira, D; de Paula Dorigam, JC; Dean, A; Deepa, M; Delatour, C; Dell'Aiera, S; Delley, MF; den Boer, RB; 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Zhou, W; Zhou, XQ; Zhou, Z; Zhu, C; Zhu, H; Zhu, L; Zhu, Y; Zitzmann, N; Zou, L; Zou, Y, 2022) |
| " Our previous work suggests that seasonal changes in melatonin secretion are important in regulating aggression in Siberian hamsters (Phodopus sungorus); it is unclear, however, how melatonin acts via its receptors to modulate seasonal variation in social behavior." | 4.12 | Adrenal MT ( Demas, GE; Dutta, S; Jasnow, AM; Munley, KM, 2022) |
| " We found that epirubicin significantly reduced the body weight, the weight of the ovaries and uteri, and the pups' number, while melatonin, which is extremely resistant to oxidation, significantly reduced these damages." | 3.96 | Melatonin protects against Epirubicin-induced ovarian damage. ( Chen, ZJ; Li, H; Li, N; Wang, N; Zhang, C; Zhu, Y, 2020) |
| "Results showed that dietary melatonin (compared to HFHS diet) was associated with a decrease in body weight, food intake, and novelty-induced behaviours; and an increase in spatial-working memory scores." | 3.96 | Dietary Melatonin Protects Against Behavioural, Metabolic, Oxidative, and Organ Morphological Changes in Mice that are Fed High-Fat, High- Sugar Diet. ( Adebisi, EO; Adeleye, AE; Olofinnade, AT; Onaolapo, AY; Onaolapo, OJ, 2020) |
| "This study investigated the protective effects of melatonin (MT) against cisplatin (CP)-induced acute kidney injury in rats as well as its possible mechanism of action associated with anti-aging protein Klotho." | 3.91 | Melatonin attenuates cisplatin-induced acute kidney injury in rats via induction of anti-aging protein, Klotho. ( Jung, TY; Kim, HC; Kim, JC; Kim, SH; Ko, JW; Lee, IC; Moon, C; Shin, IS; Shin, NR; Yun, WK, 2019) |
| " The seasonal changes in serum prolactin levels correlated positively with circulating progesterone (P) level, but inversely with circulating melatonin level during first pregnancy showing delayed development in Cynopterus sphinx." | 3.85 | Prolactin modulates luteal activity in the short-nosed fruit bat, Cynopterus sphinx during delayed embryonic development. ( Krishna, A, 2017) |
| " The altered proteins are related to the development of liver pathology, such as cirrhosis (α1-antiproteinase), thrombosis (fibrinogen, plasminogen), and inflammation (mannose-binding protein A, complement C4, complement factor B), contributing to liver steatosis or hepatic cell death." | 3.85 | High-fat diet-induced plasma protein and liver changes in obese rats can be attenuated by melatonin supplementation. ( Govitrapong, P; Isarankura-Na-Ayudhya, C; Kitidee, K; Klosen, P; Pannengpetch, S; Wongchitrat, P, 2017) |
| " This study explored the hypothesis that melatonin has beneficial functions in the mouse model of colitis induced by dextran sodium sulfate (DSS), with a specific focus on the expression of intestinal inflammatory cytokines and the serum levels of amino acids." | 3.85 | Melatonin alters amino acid metabolism and inflammatory responses in colitis mice. ( Chen, S; Fang, J; Jiang, Q; Liu, G; Ren, W; Yao, K; Yin, J; Yin, Y, 2017) |
| "The present study was aimed at evaluating the rapidity and duration of melatonin as an antidepressant in a rat model of depression." | 3.85 | Melatonin produces a rapid onset and prolonged efficacy in reducing depression-like behaviors in adult rats exposed to chronic unpredictable mild stress. ( Li, Q; Lian, B; Sun, H; Sun, L; Sun, X; Wang, G; Wang, M; Wang, Y, 2017) |
| "To determine adiponectin expression in colonic tissue of murine colitis and systemic cytokine expression after melatonin treatments and sleep deprivation." | 3.83 | Melatonin modulates adiponectin expression on murine colitis with sleep deprivation. ( Baik, HW; Choi, JW; Chung, SH; Gye, MC; Jun, JH; Kim, EK; Kim, JB; Kim, SH; Kim, TK; Lim, JY; Park, YS; Sull, JW; Sung, HJ, 2016) |
| " We sought to address these questions by 1) feeding pregnant rats with diets sufficient or deficient in DHA during gestation and lactation; 2) weaning their male offspring to diets that were sufficient or deficient in DHA; and 3) assessing depression-related behaviors (forced swim test), plasma biomarkers [brain-derived neurotrophic factor (BDNF), serotonin, and melatonin], and brain biomarkers (BDNF) in the offspring before and after puberty." | 3.81 | Dietary DHA during development affects depression-like behaviors and biomarkers that emerge after puberty in adolescent rats. ( Butt, CM; Salem, N; Weiser, MJ; Wynalda, K, 2015) |
| " Melatonin is a sleep-related neurohormone, also known to have antioxidant and anti-inflammatory effects in the gastrointestinal tract; however, the effects of melatonin on colitis have been poorly characterized." | 3.81 | Melatonin improves experimental colitis with sleep deprivation. ( Baik, HW; Chung, SH; Kim, DS; Kim, JB; Kim, JH; Kim, TK; Lee, SK; Park, YS, 2015) |
| "Previous studies indicate that the administration of melatonin caused body weight and abdominal visceral fat reductions in rodent models of hyperadiposity." | 3.81 | Melatonin counteracts changes in hypothalamic gene expression of signals regulating feeding behavior in high-fat fed rats. ( Cano-Barquilla, P; Cardinali, DP; Esquifino, AI; Jiménez-Ortega, V; Mateos, PF; Ríos-Lugo, MJ; Spinedi, EJ, 2015) |
| "The present results suggest that melatonin prevents the well-recognized increase in glucose levels that usually follows exposure to intermittent hypoxia." | 3.81 | Melatonin prevents hyperglycemia in a model of sleep apnea. ( Fagundes, M; Fiori, CZ; Kaminski, RS; Marroni, NP; Martinez, D; Martins, EF; Montanari, CC; Rosa, DP, 2015) |
| " Sleep deprivation aggravated, and melatonin attenuated the severity of colitis." | 3.80 | Melatonin attenuates dextran sodium sulfate induced colitis with sleep deprivation: possible mechanism by microarray analysis. ( Ahn, SB; Baik, HW; Chung, SH; Hong, YO; Jo, Y; Jo, YK; Jun, JH; Kim, JH; Kim, OS; Kim, SH; Kim, SS; Park, YS; Shin, JH; Son, BK, 2014) |
| "This study aimed to investigate the potential protective effects of melatonin (Mel) against aluminium-induced neurodegenerative changes in aging Wistar rats (24-28months old)." | 3.80 | Effects of melatonin on aluminium-induced neurobehavioral and neurochemical changes in aging rats. ( Allagui, MS; Badraoui, R; Bouoni, Z; Elfeki, A; Feriani, A; Murat, JC; Nciri, R; Saoudi, M, 2014) |
| "Melatonin seems to exert a protective effect on arteries from both ob/ob and CLM, counteracting the adverse effect of hypoxia and iberiotoxin." | 3.80 | Anticontractile activity of perivascular fat in obese mice and the effect of long-term treatment with melatonin. ( Agabiti-Rosei, C; Agabiti-Rosei, E; De Ciuceis, C; Favero, G; Heagerty, AM; Porteri, E; Rezzani, R; Rizzoni, D; Rodella, LF; Rossini, C; Withers, SB, 2014) |
| "Chronic melatonin treatment has been shown to prevent the harmful effects of diet-induced obesity and reduce myocardial susceptibility to ischaemia-reperfusion injury (IRI)." | 3.80 | Short-term melatonin consumption protects the heart of obese rats independent of body weight change and visceral adiposity. ( Blackhurst, D; Huisamen, B; Lochner, A; Nduhirabandi, F; Strijdom, H, 2014) |
| "Although melatonin supplementation is known to influence numerous physiological functions, little is however known of its effects on pregnancy outcome." | 3.79 | Effect of melatonin supplementation on pregnancy outcome in Wistar-Kyoto and Sprague-Dawley rats. ( Gupalo, S; Omar, E; Saleh, HI; Singh, HJ, 2013) |
| " Moreover these rats exhibited anhedonia in a sucrose consumption test, and increased grooming in the open-field test, which reflects an anxiety-like condition." | 3.79 | Disruption of circadian rhythms due to chronic constant light leads to depressive and anxiety-like behaviors in the rat. ( Angeles-Castellanos, M; Escobar, C; Salgado-Delgado, R; Tapia-Osorio, A, 2013) |
| "Piromelatine, similar to melatonin, has an antihypertensive effect and also attenuates body weight, improves metabolic profiles and might be useful in the treatment of hypertension and the metabolic syndrome." | 3.79 | Blood pressure reducing effects of piromelatine and melatonin in spontaneously hypertensive rats. ( Ding, L; He, P; Hou, Y; Huang, L; Laudon, M; She, M; Wang, H; Wang, Z; Yang, S; Yin, W; Zhang, C, 2013) |
| "In this study, we examined whether melatonin improves metabolic syndrome induced by high fructose intake in male Wistar rats." | 3.78 | Melatonin improves metabolic syndrome induced by high fructose intake in rats. ( Kitagawa, A; Ohashi, K; Ohta, Y, 2012) |
| "Microwave radiation causes body mass decrease and anxiety related behaviour in rats, however melatonin causes a reverse of those effects on both body weight and behaviour of irradiated animals (Fig." | 3.78 | The effect of melatonin on body mass and behaviour of rats during an exposure to microwave radiation from mobile phone. ( Babovic, P; Djordjevic, B; Jankovic, A; Kocic, G; Radovanovic, Z; Ristic, G; Sokolovic, D; Sokolovic, DM; Stanojkovic, Z; Veljkovic, A, 2012) |
| " Concomitantly, UChB Co + M and UChB EtOH + M groups were infused with vehicle + melatonin (100 μg/100 g body weight/d) intraperitoneally over 60 days." | 3.77 | Long-term exogenous melatonin treatment modulates overall feed efficiency and protects ovarian tissue against injuries caused by ethanol-induced oxidative stress in adult UChB rats. ( Almeida-Francia, CC; Amorim, JP; Chuffa, LG; de Mello Júnior, W; Fioruci, BA; Martinez, FE; Martinez, M; Mendes, LO; Novelli, EL; Pinheiro, PF; Seiva, FR; Teixeira, GR, 2011) |
| "Melatonin effect on body weight progression, mean levels and 24-hr pattern of circulating adiponectin, leptin, insulin, glucose, triglycerides and cholesterol were examined in rats fed a normal or a high-fat diet." | 3.76 | Melatonin effect on plasma adiponectin, leptin, insulin, glucose, triglycerides and cholesterol in normal and high fat-fed rats. ( Cano, P; Cardinali, DP; Esquifino, AI; Fernández-Mateos, MP; Jiménez-Ortega, V; Ríos-Lugo, MJ; Scacchi, PA, 2010) |
| " Animals were then tested for reward-seeking behaviour (saccharin consumption), anxiety (elevated plus-maze), aggression (resident-intruder test), and depression-like behaviour (FST)." | 3.75 | We are in the dark here: induction of depression- and anxiety-like behaviours in the diurnal fat sand rat, by short daylight or melatonin injections. ( Ashkenazy, T; Einat, H; Kronfeld-Schor, N, 2009) |
| " The aim of this study was to investigate the protective effects in rat maternal and fetal livers as also the placenta of melatonin or silymarin against the oxidative stress and apoptosis induced by maternal obstructive cholestasis during the last third of pregnancy (OCP)." | 3.74 | Multiple protective effects of melatonin against maternal cholestasis-induced oxidative stress and apoptosis in the rat fetal liver-placenta-maternal liver trio. ( Castaño, B; Gonzalez-Buitrago, JM; Marin, JJ; Perez, MJ, 2007) |
| "The study in ovariectomized (Ovx) rats, as a model of menopausal status, of the effects of melatonin (M) and/or estradiol (E), associated or not with food restriction, on body weight (BW) and serum leptin levels." | 3.74 | Melatonin and estradiol effects on food intake, body weight, and leptin in ovariectomized rats. ( Alonso-Gonzalez, C; Cos, S; Gonzalez, A; Martinez-Campa, CM; Mediavilla, MD; Sanchez-Barcelo, EJ; Sanchez-Mateos, S, 2007) |
| "Melatonin secretion decreased in fructose fed rats that developed hypertension." | 3.74 | The role of melatonin in the pathogenesis of hypertension in rats with metabolic syndrome. ( Grossman, E; Leibowitz, A; Peleg, E; Shabtai, Z; Shamiss, A; Sharabi, Y, 2008) |
| "In order to assess whether light exposure at night influences the growth of mammary tumors, as well as the role of melatonin in this process, female rats bearing DMBA-induced mammary adenocarcinomas were exposed to different lighting environments." | 3.73 | Exposure to light-at-night increases the growth of DMBA-induced mammary adenocarcinomas in rats. ( Alonso-González, C; Cos, S; González, A; Martínez-Campa, C; Mediavilla, D; Sánchez-Barceló, EJ, 2006) |
| "In this study, we investigated the effects of melatonin on adriamycin-induced cardiotoxicity both in vivo in rats and in vitro, and on the antitumor activities of adriamycin on MDA-231 and NCI breast cancer cells." | 3.73 | Modulation by melatonin of the cardiotoxic and antitumor activities of adriamycin. ( Cuong, DV; Han, J; Joo, H; Kim, C; Kim, E; Kim, N; Min, CK; Park, WS; Park, YS; Youm, JB, 2005) |
| " Melatonin has been known to regulate body weight on various species including rodents." | 3.73 | Melatonin enhances NADPH-diaphorase activities in the hypothalamus of maternally-separated rats. ( Chang, UJ; Chung, JH; Kim, HK; Kim, JW; Kim, MJ; Kim, YO; Oh, DJ, 2006) |
| " Squirrels of set 1 (groups A and B) received only normal saline, set 2 (groups C and D) received 25 microg/100 g body weight (bwt) melatonin and set 3 (groups E and F) received 25 microg/100 g bwt vitamin E for four weeks." | 3.73 | Melatonin prevents X-ray irradiation induced oxidative damagein peripheral blood and spleen of the seasonally breeding rodent, Funambulus pennanti during reproductively active phase. ( Haldar, C; Sharma, S, 2006) |
| "Both plasma melatonin levels and hypothalamic arcuate nucleus pro-opiomelanocortin (POMC) (biosynthetic precursor to the endogenous opioid ss-endorphin and other opiomelanocortins) mRNA content decrease with aging." | 3.72 | Suppression of hypothalamic pro-opiomelanocortin (POMC) gene expression by daily melatonin supplementation in aging rats. ( Boldt, BM; Marck, BT; Matsumoto, AM; Rasmussen, DD; Yellon, SM, 2003) |
| "To assess the effect of melatonin on bone metabolism in ovariectomized rats, receiving oestradiol therapy or not, melatonin was administered in the drinking water (25 microg/mL water) and oestradiol (10 microg/kg body weight) or vehicle was given subcutaneously 5 days/week for up to 60 days after surgery." | 3.72 | Melatonin increases oestradiol-induced bone formation in ovariectomized rats. ( Albornoz, LE; Boggio, V; Cardinali, DP; Castrillón, PO; Ladizesky, MG; Mautalen, C, 2003) |
| "We previously demonstrated that daily melatonin administration to middle-aged rats, restoring nocturnal plasma melatonin to young adult levels, decreased body weight and suppressed visceral fat and plasma leptin." | 3.72 | Melatonin effects on metabolism independent of gonad function. ( Green, JN; Puchalski, SS; Rasmussen, DD, 2003) |
| "To determine whether suppression of melatonin secretion without surgery in chickens can result in scoliosis development." | 3.72 | Effect of melatonin suppression on scoliosis development in chickens by either constant light or surgical pinealectomy. ( Cheung, KM; Leong, JC; Lu, DS; Luk, KD; Poon, AM; Wang, T, 2003) |
| "The aim of this study was to investigate structural changes that occurred in the skeletal muscle of rats with experimental hyperthyroidism and the effect of melatonin on these changes." | 3.72 | Effects of melatonin on skeletal muscle of rats with experimental hyperthyroidism. ( Oner, J; Ozan, E, 2003) |
| "The aim of the present study was to test the hypothesis that the natural antioxidant melatonin (MEL) and the synthetic antioxidant stobadine (STO) could reduce the incidence of maternal and embryofoetal toxicity in rats due to intrauterine hypoxia." | 3.72 | Effect of melatonin and stobadine on maternal and embryofoetal toxicity in rats due to intrauterine hypoxia induced by phenytoin administration. ( Brucknerová, I; Dubovický, M; Juránek, I; Mach, M; Navarová, J; Soltés, L; Ujházy, E; Zeman, M, 2004) |
| "It is generally accepted that antioxidant properties of melatonin significantly contribute to its antiaging effect." | 3.71 | Antioxidant and antiaging activity of N-acetylserotonin and melatonin in the in vivo models. ( Bachurin, S; Oxenkrug, G; Requintina, P, 2001) |
| " To assess the effect of aging and accelerated aging on the circadian pacemaker of this primate, we measured body weight variations, the daily rhythm in urine 6-sulfatoxymelatonin and the light-induced expression of the immediate early gene (Fos) in the suprachiasmatic nucleus of mouse lemurs that had been exposed to different photoperiodic cycles." | 3.71 | Artificially accelerated aging by shortened photoperiod alters early gene expression (Fos) in the suprachiasmatic nucleus and sulfatoxymelatonin excretion in a small primate, Microcebus murinus. ( Aujard, F; Claustrat, B; Cooper, HM; Dkhissi-Benyahya, O; Fournier, I; Perret, M; Schilling, A, 2001) |
| " Changes in body weight, subcutaneous body fat measured to provide an estimate of total body fat, and circulating concentrations of leptin were compared throughout the 1-yr experimental period." | 3.70 | Photoperiodic versus metabolic signals as determinants of seasonal anestrus in the mare. ( Fitzgerald, BP; McManus, CJ, 2000) |
| "These results demonstrate that the duration of melatonin-receptor exposure per day determines the onset of seasonal obesity in garden dormice and, on the other hand, that restriction of melatonin-receptor exposure by pharmacological treatment prevents it." | 3.69 | Effects of both a melatonin agonist and antagonist on seasonal changes in body mass and energy intake in the garden dormouse. ( Ambid, L; Atgié, C; Casteilla, L; Delagrange, P; Guardiola-Lemaitre, B; Hanoun, N; Le Gouic, S; Lesieur, D; Nibbelink, M; Renard, P, 1996) |
| " injections of 1,2-dimethylhydrazine (DMH) at a single dose of 21 mg/kg of body weight." | 3.69 | Melatonin and colon carcinogenesis: I. Inhibitory effect of melatonin on development of intestinal tumors induced by 1,2-dimethylhydrazine in rats. ( Anisimov, VN; Popovich, IG; Zabezhinski, MA, 1997) |
| " Previously, we have shown that lesions of the suprachiasmatic nucleus of the hypothalamus (SCNx) block regression of the testes and decreases in body weight and EWAT caused by short day-like, timed daily subcutaneous melatonin infusions in pinealectomized Siberian hamsters and elevate dramatically serum PRL concentrations." | 3.68 | Hyperprolactinemia does not promote testicular recrudescence in photoregressed Siberian hamsters. ( Bartness, TJ; Whitten, RD; Youngstrom, TG, 1993) |
| "Plasma melatonin levels were measured at three-hourly intervals over 24 hours in 11 women with untreated anorexia nervosa, and in nine healthy women of normal weight." | 3.68 | Plasma melatonin levels in anorexia nervosa. ( Arendt, J; Bhanji, S; Franey, C; Mattingly, D, 1992) |
| "To investigate whether the function of pinealocytes is altered in obesity, nocturnal melatonin (MT) secretion was determined in nine healthy subjects and compared with that of eight obese individuals." | 3.68 | Effect of short-term fasting on nocturnal melatonin secretion in obesity. ( Röjdmark, S; Rössner, S; Wetterberg, L, 1992) |
| "In male Syrian hamsters daily evening melatonin injections resulted in increased circulating levels of growth hormone (GH), as well as a modest increase in body weight." | 3.68 | Melatonin increases serum growth hormone and insulin-like growth factor I (IGF-I) levels in male Syrian hamsters via hypothalamic neurotransmitters. ( Borer, KT; Sheppard, MS; Vriend, J, 1990) |
| "This study examined whether melatonin-induced inhibition of testicular weight and body weight in vivo could be antagonized by luzindole, a competitive melatonin receptor antagonist, or methysergide, a competitive serotonin receptor antagonist." | 3.68 | Effects of melatonin agonists and antagonists on reproduction and body weight in the Siberian hamster. ( Dubocovich, ML; Duncan, MJ; Fang, JM, 1990) |
| "Two experiments examined the effects of photoperiod, melatonin, and diet on body weight in female Syrian hamsters (Mesocricetus auratus)." | 3.67 | Seasonal obesity in Syrian hamsters: effects of age, diet, photoperiod, and melatonin. ( Bartness, TJ; Wade, GN, 1984) |
| "Administration of the pineal hormone melatonin (1 mg/day) to growing female rats provided significant protection against the injurious effects (decrease of body weight gain and atrophy of the thymus and adrenals) caused by a glucocorticoid, dexamethasone (0." | 3.67 | Melatonin protects rats from injurious effects of a glucocorticoid, dexamethasone. ( Aoyama, H; Mori, N; Mori, W, 1984) |
| "Two experiments examined the effects of gonadectomy, photoperiod, and melatonin treatment on food intake, body weight, and carcass composition in male and female Siberian hamsters (Phodopus sungorus sungorus)." | 3.67 | Effects of photoperiod and gonadectomy on food intake, body weight, and body composition in Siberian hamsters. ( Bartness, TJ; Wade, GN, 1984) |
| "Disturbances were studied in the nocturnal circadian pattern of serum melatonin and plasma cortisol levels in 33 female patients with an eating disorder (anorexia nervosa, n = 11; bulimia nervosa, n = 12; or both, n = 10) and in ten female control subjects of comparable age." | 3.67 | Changes in melatonin levels but not cortisol levels are associated with depression in patients with eating disorders. ( Brown, GM; Costa, D; Garfinkel, PE; Kennedy, SH; Parienti, V, 1989) |
| "To clarify a controversy as to whether melatonin secretion is related to body weight, urinary sulphatoxymelatonin (aMT6s) excretion was estimated in 10 patients with anorexia nervosa before and after weight gain, and compared with 10 age-matched controls." | 3.67 | A study of sulphatoxymelatonin excretion and gonadotrophin status during weight gain in anorexia nervosa. ( Arendt, J; Bearn, J; Checkley, SA; Franey, C; Murphy, M; Treasure, J; Wheeler, M, 1988) |
| "The effects of the pineal indole melatonin on a transplantable androgen-insensitive fast-growing rat prostatic adenocarcinoma, the Dunning R 3327 HIF tumor, were examined." | 3.67 | Studies on the effects of the pineal hormone melatonin on an androgen-insensitive rat prostatic adenocarcinoma, the Dunning R 3327 HIF tumor. ( Buzzell, GR, 1988) |
| "The mean 24-hour secretion and circadian rhythm of melatonin were studied in 12 female subjects with anorexia nervosa (AN), 13 massively obese (OB) women, and 9 normal weight healthy volunteers to investigate the relationship between type of feeding behavior and hormonal secretory pattern." | 3.67 | Melatonin circadian rhythm in anorexia nervosa and obesity. ( Bossolo, PA; Brambilla, F; Esposti, G; Ferrari, E; Fraschini, F; Marelli, G, 1988) |
| "Administration of the pineal hormone melatonin to young female rats provided significant prevention of the injurious effects (decrease of body weight gain, atrophy of the thymus and adrenals, glucosuria, elevation of the blood level of glucose, free fatty acid, triglyceride, and total cholesterol) caused by three different glucocorticoids, i." | 3.67 | Anti-glucocorticoid effects of melatonin in young rats. ( Aoyama, H; Mori, N; Mori, W, 1986) |
| " After 15 days, the 40 mg dosage was decreased to 20mg/kg body weight for an additional 20 days (35 days of PTU)." | 2.73 | Serum thyroid hormones and performance of offspring in ewes receiving propylthiouracil with or without melatonin. ( Duffey, JL; Gifford, CA; Hallford, DM; Knight, RL, 2007) |
| "Melatonin is a neurohormone, which plays multiple roles in regulating inflammation, blood pressure, insulin actions, and energy metabolism." | 2.66 | Elucidating the Regulatory Role of Melatonin in Brown, White, and Beige Adipocytes. ( Liu, J; Shan, T; Wang, Y; Xu, Z; You, W, 2020) |
| "Melatonin has been shown to have beneficial effects in cardiovascular disorders including ischaemic heart disease and hypertension." | 2.48 | Melatonin and the metabolic syndrome: a tool for effective therapy in obesity-associated abnormalities? ( du Toit, EF; Lochner, A; Nduhirabandi, F, 2012) |
| "Melatonin is a neurohormone synthesized in the pineal gland during the dark period in all species, including humans." | 2.42 | Therapeutic perspectives for melatonin agonists and antagonists. ( Atkinson, J; Boutin, JA; Casteilla, L; Delagrange, P; Lesieur, D; Misslin, R; Pellissier, S; Pénicaud, L; Renard, P, 2003) |
| "Melatonin is a hormone secreted by the pineal gland." | 1.91 | Histological study of the role of CD34+ stem cells and mast cells in cyclophosphamide-induced thymic injury in rats and the possible attenuating role of melatonin. ( Hamed, WHE; Mazroa, SA; Moustafa, AM; Shrief, AI, 2023) |
| "Melatonin (Mel) is a hormone secreted by the pineal gland that regulates the circadian rhythms and improves obesity." | 1.91 | Effects of Melatonin Supplementation on Lipid Metabolism and Body Fat Accumulation in Ovariectomized Rats. ( Chien, YW; Hsu, LW, 2023) |
| "Melatonin is an indole-like neuroendocrine hormone." | 1.72 | Melatonin promotes the growth and development of lambs by increasing growth hormone and testosterone, targeting on apoptosis signaling pathway and intestinal microflora. ( Guan, S; Guo, X; Ji, P; Li, G; Liu, F; Liu, G; Ma, W; Wang, L; Wu, H; Wusiman, A; Xu, S; Yan, L; Zhao, M, 2022) |
| "Melatonin is a sleep-related neurohormone and affected by the circadian rhythm and light/dark cycles." | 1.72 | Melatonin protects against body weight gain induced by sleep deprivation in mice. ( Hu, S; Liu, X; Wang, Y; Wei, S; Zhang, R, 2022) |
| "Melatonin (ML) is a potent antioxidant that reduces oxidative stress." | 1.62 | Melatonin Alleviated Potassium Dichromate-Induced Oxidative Stress and Reprotoxicity in Male Rats. ( Ahmed-Farid, OA; Al-Tamimi, J; Alhazza, IM; Bashandy, SAE; Ebaid, H; Omara, EA, 2021) |
| "Melatonin was administered at a dose of 10 mg/kg in drinking water every day for 20 days at night." | 1.56 | Protective action of melatonin on diabetic rat testis at cellular, hormonal and immunohistochemical levels. ( Alves, ÉR; Ferreira, CGM; Melo, IMF; Neto, CJCL; Santos, LCDS; Silva Junior, VAD; Silva, MVD; Teixeira, ÁAC; Vieira Filho, LD; Wanderley Teixeira, V, 2020) |
| "Treatment with melatonin in CLE rats showed reduced level of MDA, PMRS, PCO, AOPPs and AGEs while GSH and FRAP activity were increased." | 1.51 | Redox homeostasis in a rodent model of circadian disruption: Effect of melatonin supplementation. ( Rizvi, SI; Singh, S; Verma, AK, 2019) |
| "Melatonin was administered at the dose of 1,2 mcg per capita (an equivalent to pediatric dosages) at days 1, 3 and 5 postpartum to 129/Sv mice, which were followed thereafter till their natural deaths." | 1.51 | [Gender-specific effects of neonatal administration of melatonin on lifespan and age-associated patholgy in 129/Sv mice.] ( Anisimov, VN; Golubev, AG; Popovich, IG; Tyndyk, ML; Yurova, MN, 2019) |
| "Leptin is an adipokine secreted in a manner dependent on the circadian rhythm that ultimately reduces food intake." | 1.48 | Melatonin Prevents the Harmful Effects of Obesity on the Brain, Including at the Behavioral Level. ( Bermejo-Millo, JC; Boga, JA; Caballero, B; Coto-Montes, A; de Luxán-Delgado, B; Pérez-Martínez, Z; Potes, Y; Rubio-González, A; Solano, JJ; Vega-Naredo, I, 2018) |
| "Melatonin treatment to diabetic rats restored the alteration in physiological and biochemical markers." | 1.48 | Protective Role of Melatonin in Streptozotocin Induced Pancreatic Damages in Diabetic Wistar Rat. ( Ahmad Hajam, Y; Basheer, M; Ghosh, H; Rai, S; Singh, S, 2018) |
| "Melatonin has been shown to palliate different lesions by scavenging free radicals, but its role in the reduction of the fluoxetine-induced injuries has been little known." | 1.46 | Protective effects of melatonin on long-term administration of fluoxetine in rats. ( Khaksar, M; Oryan, A; Rahbarghazi, R; Rezabakhsh, A; Sayyari, M, 2017) |
| "Fibromyalgia is a chronic syndrome characterized by widespread musculoskeletal pain and an extensive array of other symptoms including disordered sleep, fatigue, depression and anxiety." | 1.46 | Oral Supplementation of Melatonin Protects against Fibromyalgia-Related Skeletal Muscle Alterations in Reserpine-Induced Myalgia Rats. ( Bonomini, F; Favero, G; Lavazza, A; Rezzani, R; Rodella, LF; Stacchiotti, A; Trapletti, V, 2017) |
| "Melatonin treatment significantly affected total activity time, number of lateral approaches and mount attempts in comparison to controls." | 1.42 | Melatonin administration enhances the reproductive capacity of young rams under a southern Mediterranean environment. ( Ben Salem, I; Fehri, Y; Hilali, ME; Lassoued, N; Rekik, M; Sakly, C; Taboubi, R, 2015) |
| "Melatonin plays a protective role in type 2 diabetes (T2D) through regulation of glucose metabolism." | 1.42 | Transcutaneous vagus nerve stimulation induces tidal melatonin secretion and has an antidiabetic effect in Zucker fatty rats. ( Li, S; McCabe, MF; Rong, P; Wang, S; Wang, X; Zhai, X, 2015) |
| "Melatonin is known to be a strong antioxidant and has a free radical scavenging ability." | 1.42 | Protective effects of melatonin against 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced cardiac injury in rats. ( Ceker, G; Ciftci, O; Parlakpinar, H; Sagir, M; Sarihan, ME; Yilmaz, F; Yilmaz, O, 2015) |
| "21 mW/cm(2)) and specific absorption rate (SAR 0." | 1.40 | Therapeutic approaches of melatonin in microwave radiations-induced oxidative stress-mediated toxicity on male fertility pattern of Wistar rats. ( Kesari, KK; Kumar, J; Kumari, K; Meena, R; Rajamani, P; Verma, HN, 2014) |
| "Melatonin was administered in drinking water at the dose of 0." | 1.40 | Melatonin prevents neonatal dexamethasone induced programmed hypertension: histone deacetylase inhibition. ( Chien, SJ; Huang, LT; Kuo, HC; Lin, IC; Tain, YL; Wu, TH, 2014) |
| "The melatonin pretreated irradiated rats showed less change in body weight as compared to radiation only group." | 1.40 | Consequences of lethal-whole-body gamma radiation and possible ameliorative role of melatonin. ( Aliasgharzadeh, A; Mahdavi, SR; Mihandoost, E; Shirazi, A, 2014) |
| "Body weights were taken on days 7, 14 and 21." | 1.40 | Effects of vitamin E and melatonin on serum testosterone level in sleep deprived Wistar rats. ( Adeyemi, DH; Akindele, OO; Kunle-Alabi, OT; Oghenetega, BO; Raji, Y, 2014) |
| "Melatonin co-treatment decreased lead-induced oxidative stress (peroxidation level) and toxic effects on kidneys without altering the lead-induced reduction in renal NO." | 1.39 | Melatonin attenuates the effects of sub-acute administration of lead on kidneys in rats without altering the lead-induced reduction in nitric oxide. ( Alcaraz-Contreras, Y; Cárabez-Trejo, A; de Larrea, GZ; Gallegos-Corona, MA; Gutiérrez-Granados, S; Martínez-Alfaro, M; Ramírez-García, G, 2013) |
| "Melatonin was higher in children with predominantly hyperactive-impulsive/conduct disorder subtype." | 1.39 | Methylphenidate effects on blood serotonin and melatonin levels may help to synchronise biological rhythms in children with ADHD. ( Augustin-Morales, MD; Contreras-Chova, F; Cubero-Millán, I; Justicia-Martínez, F; Khaldy-Belkadi, H; Molina-Carballo, A; Muñoz-Hoyos, A; Naranjo-Gómez, A; Ruiz-Ramos, MJ; Uberos, J, 2013) |
| "The melatonin treatment resulted in increased hind-limb motor function and decreased iNOS mRNA expression in the L/D condition compared with the LL condition (P < 0." | 1.38 | Beneficial effects of endogenous and exogenous melatonin on neural reconstruction and functional recovery in an animal model of spinal cord injury. ( Chang, KT; Hong, Y; Jeon, JC; Kim, JH; Lee, S; Lee, SK; Lee, SR; Lee, Y; Park, K; Park, S, 2012) |
| "Melatonin treatment did not affect clutch size." | 1.38 | Melatonin delays clutch initiation in a wild songbird. ( Beltrami, G; Greives, TJ; Hau, M; Kingma, SA, 2012) |
| " When combined at a dosage either positively or negatively skewed from each optimal dosage, however, co-treatment caused synergistic neuroprotection." | 1.37 | Melatonin protects against transient focal cerebral ischemia in both reproductively active and estrogen-deficient female rats: the impact of circulating estrogen on its hormetic dose-response. ( Chen, HY; Chen, TY; Huang, SY; Hung, YC; Lee, AC; Lee, EJ; Lee, MY; Shen, CC; Tai, SH; Wu, TS, 2011) |
| "In addition, this treatment improved fatty liver, decreased hepatic triglyceride concentration and increased apolipoprotein B100 in liver tissue." | 1.37 | Melatonin improves mitochondrial respiratory chain activity and liver morphology in ob/ob mice. ( Fernández-Moreira, D; García Ruiz, I; García-Consuegra, I; Gómez-Izquierdo, E; Muñoz-Yagüe, T; Solís-Herruzo, JA; Solís-Muñoz, P, 2011) |
| "Melatonin has been reported to be neuroprotective in the 6-hydroxydopamine (6-OHDA) and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) models of PD." | 1.36 | Melatonin treatment potentiates neurodegeneration in a rat rotenone Parkinson's disease model. ( Cannon, JR; Greenamyre, JT; Tapias, V, 2010) |
| "Melatonin has a protective role in type 2 diabetes; however, its synthesis itself is affected in the disease." | 1.36 | Adrenoceptor expression and diurnal rhythms of melatonin and its precursors in the pineal gland of type 2 diabetic goto-kakizaki rats. ( Bach, AG; Mühlbauer, E; Peschke, E, 2010) |
| "Corticosterone-treated mice exhibited a reduced spine density, which was ameliorated by melatonin administration." | 1.36 | Melatonin treatment mimics the antidepressant action in chronic corticosterone-treated mice. ( Bramanti, P; Crupi, R; Cuzzocrea, S; La Spada, G; Marino, A; Mazzon, E; Spina, E, 2010) |
| "Melatonin treatment significantly improved the number of fertilized embryos/corpus luteum (CL) (-MEL: 0." | 1.36 | Effects of exogenous melatonin on in vivo embryo viability and oocyte competence of undernourished ewes after weaning during the seasonal anestrus. ( Abecia, JA; Casao, A; Forcada, F; Vázquez, MI, 2010) |
| "Melatonin-treated rats received 0." | 1.36 | Melatonin prevents hypertension and increased asymmetric dimethylarginine in young spontaneous hypertensive rats. ( Huang, LT; Lau, YT; Lin, CY; Lin, IC; Tain, YL, 2010) |
| "The malondialdehyde (MDA) level was determined for the effect of oxidative stress." | 1.35 | Melatonin attenuates lipopolysaccharide-induced acute lung inflammation in sleep-deprived mice. ( Baik, HW; Baik, TK; Kim, BJ; Kim, JY; Kim, OS; Kwak, YJ; Lee, JH; Lee, KH; Lee, SK; Lee, YD; Song, DY, 2009) |
| "Pretreatment with melatonin counteracted 2-BP-induced oxidative stress, ameliorated apoptosis in testis and attenuated histopathological damage in testis." | 1.35 | Melatonin pretreatment attenuates 2-bromopropane-induced testicular toxicity in rats. ( Huang, F; Huang, Y; Ichihara, G; Ning, H; Wang, H; Xin, QQ; Xu, DX; Ye, DQ; Zhang, ZH, 2009) |
| "Treatment with melatonin (5 mg/kg and 10 mg/kg, ip) significantly improved locomotor activity, weight loss and antianxiety effect as compared with control (sleep-deprived)." | 1.35 | Possible involvement of GABAergic mechanism in protective effect of melatonin against sleep deprivation-induced behaviour modification and oxidative damage in mice. ( Kumar, A; Singh, A, 2009) |
| "Melatonin was administered in tap water (4 microg/ml) daily from the 6th month of age." | 1.35 | Prolonged melatonin administration in 6-month-old Sprague-Dawley rats: metabolic alterations. ( Ahlers, I; Ahlersová, E; Bojková, B; Datelinka, I; Friedmanová, L; Kassayová, M; Orendás, P, 2008) |
| "Melatonin and leptin were measured by radioimmunoanalysis." | 1.34 | Longitudinal study of the simultaneous secretion of melatonin and leptin during normal puberty. ( Contreras-Chova, F; Fernández-Tardáguila, E; Molina-Carballo, A; Muñoz-Hoyos, A; Seiquer, I; Uberos-Fernández, J, 2007) |
| "Melatonin tended to increase plasma sodium concentration, did decrease plasma osmolality, but did not affect potassium concentration." | 1.34 | Effect of melatonin on salt gland and kidney function of gulls, Larus glaucescens. ( Bennett, DC; Gray, DA; Hughes, MR; Kitamura, N; Poon, AM; Sharp, PJ, 2007) |
| "Melatonin is a potent free radical scavenger and an indirect antioxidant." | 1.34 | Melatonin levels during the first week of life and their relation with the antioxidant response in the perinatal period. ( Avila-Villegas, R; Bonillo-Perales, A; Florido-Navío, J; González-Ripoll, M; Molina-Carballo, A; Muñoz-Hoyos, A; Uberos, J, 2007) |
| "Melatonin was administered during the BOP-induction phase (12 wk) and/or following the postinduction phase (12 wk)." | 1.34 | Beneficial properties of melatonin in an experimental model of pancreatic cancer. ( Cruz, A; González, R; Montilla, P; Muñoz-Villanueva, MC; Muntané, J; Padillo, FJ; Perea, MD; Romero, A; Ruiz-Rabelo, JF; Túnez, I; Vázquez, R, 2007) |
| " In addition, long-term administration of melatonin to rats leads to an increase in both leptin and zinc concentrations." | 1.34 | Pinealectomy and melatonin administration in rats: their effects on plasma leptin levels and relationship with zinc. ( Baltaci, AK; Mogulkoc, R, 2007) |
| " Exogenous melatonin administration caused delays in the acrophases of T3, T4 and melatonin rhythm itself; whereas advances in the acrophases of TSH were observed, thus indicating chronic administration of melatonin could alter the characteristics of endocrine rhythms." | 1.33 | Temporal oscillations of thyroid hormones in long term melatonin treated rats. ( Mirunalini, S; Subramanian, P, 2005) |
| "Melatonin co-treatment brought about a significant increase in the hepatic (61%), renal (79%) and intestinal (77%) Cd concentrations as compared to those in the Cd alone group." | 1.33 | Melatonin increases tissue accumulation and toxicity of cadmium in the bank vole (Clethrionomys glareolus). ( Bonda, E; Chwełatiuk, E; Krasowska, A; Włostowski, T, 2005) |
| "Melatonin (M) is an indolamine secreted by the pineal gland." | 1.33 | Melatonin as protective agent for the cytotoxic effects of diazinon in the spermatogenesis in the earthworm Eisenia foetida. ( Bustos-Obregón, E; Espinoza, O; González, JR, 2005) |
| "Melatonin treatment caused a sharp decrease in the elevated serum glucose, a slight increase in the lowered serum insulin concentrations and small partial regeneration/proliferation of beta-cells of islets." | 1.33 | Depression of glucose levels and partial restoration of pancreatic beta-cell damage by melatonin in streptozotocin-induced diabetic rats. ( Kanter, M; Karaca, T; Sagmanligil, HO; Uysal, H, 2006) |
| "The influences of chronic administration of low and high doses of melatonin on the characteristics of circadian rhythms of glucose, reduced glutathione, total protein were studied, in order to investigate whether melatonin could modulate these rhythms differently." | 1.33 | Modulation of biochemical circadian rhythms during long-term melatonin treatment in rats. ( Sankaran, M; Subramanian, P, 2006) |
| "Melatonin is a highly effective treatment in different animal models of excitotoxicity or ischemia/reperfusion injury." | 1.33 | Preclinical evaluation of pharmacokinetics and safety of melatonin in propylene glycol for intravenous administration. ( Chan, PS; Cheung, RT; Ma, ES; Tam, S; Tipoe, GL; Zou, LY, 2006) |
| "Melatonin was administered as an antioxidant." | 1.32 | Melatonin reduces renal interstitial inflammation and improves hypertension in spontaneously hypertensive rats. ( Nava, M; Quiroz, Y; Rodriguez-Iturbe, B; Vaziri, N, 2003) |
| "This melatonin treatment induces gonadal regression in photosensitive but not in photorefractory hamsters." | 1.32 | Termination of neuroendocrine refractoriness to melatonin in Siberian hamsters (Phodopus sungorus). ( Freeman, DA; Kauffman, AS; Zucker, I, 2003) |
| "Treatment with melatonin changed them to near control values." | 1.32 | Effects of melatonin on oxidative-antioxidative status of tissues in streptozotocin-induced diabetic rats. ( Aksoy, N; Aksoy, S; Sabuncu, T; Vural, H, 2003) |
| "Melatonin has been reported to have antioxidant properties in addition to its known hormonal activities." | 1.32 | Melatonin-induced reduction in age-related accumulation of oxidative damage in mice. ( Bhatia, AL; Manda, K, 2003) |
| "Melatonin treatment reversed STZ-induced reduction of GSH-Px activity without having an effect on blood glucose." | 1.32 | Protective effects of chronic melatonin treatment against renal injury in streptozotocin-induced diabetic rats. ( Bukan, N; Cam, M; Ercan, F; Guven, A; Ustündag, N; Yavuz, O, 2003) |
| "Melatonin was administered intraperitoneally to the animals 30 min before radiation exposure." | 1.32 | Protective effect of melatonin against fractionated irradiation-induced epiphyseal injury in a weanling rat model. ( Karslioglu, I; Kosucu, P; Sener, M; Ulku, C; Yaris, E; Yavuz, AA; Yavuz, MN, 2003) |
| "Melatonin has been reported to reduce infarct volumes induced by transient middle cerebral artery (MCA) occlusion." | 1.32 | Delayed treatment with melatonin enhances electrophysiological recovery following transient focal cerebral ischemia in rats. ( Chang, GL; Chen, TY; Chuang, JI; Lee, EJ; Lee, MY; Tsai, YY; Wu, TS, 2004) |
| "Treatment with melatonin (EC(50) 4." | 1.32 | Melatonin treatment protects against diabetes-induced functional and biochemical changes in rat aorta and corpus cavernosum. ( Ayanğolu-Dülger, G; Paskaloglu, K; Sener, G, 2004) |
| "Melatonin secretion was not affected by food supply." | 1.31 | Determinants of the annual pattern of reproduction in mature male Merino and Suffolk sheep: modification of responses to photoperiod by an annual cycle in food supply. ( Blache, D; Blackberry, MA; Boukhliq, RC; Fisher, JS; Hötzel, MJ; Martin, GB; Miller, DW; Walkden-Brown, SW, 2002) |
| "Melatonin-treated rats that were then crossed over to control treatment for a further 12 weeks gained BW, whereas control rats that were crossed to melatonin treatment lost BW, but food intake did not change in either group." | 1.31 | Daily melatonin administration to middle-aged male rats suppresses body weight, intraabdominal adiposity, and plasma leptin and insulin independent of food intake and total body fat. ( Matsumoto, AM; McCants, RL; Mitton, DR; Rasmussen, DD; Wilkinson, CW; Wolden-Hanson, T; Yellon, SM, 2000) |
| "Within the Cd plus MLT-treated group, the body weight gains and relative thymus weights were significantly increased when compared with the treatment of Cd alone." | 1.31 | Influence of melatonin on immunotoxicity of cadmium. ( Ahn, YK; Kim, JH; Kim, YO, 2000) |
| "Melatonin treatment were performed only during the night (between 18:00 to 09:00) in order to maintain their circadian rhythm, since serum melatonin levels are high at midnight." | 1.31 | Inhibitory effects of low doses of melatonin on induction of preneoplastic liver lesions in a medium-term liver bioassay in F344 rats: relation to the influence of electromagnetic near field exposure. ( Asamoto, M; Futakuchi, M; Hagiwara, A; Imaida, K; Ogawa, K; Sano, M; Shirai, T; Tamano, S; Yoshino, H, 2000) |
| "Within the Pb plus MLT-treated group, the body weight gains and the relative thymus weights were significantly increased when compared with the treatment of Pb alone." | 1.31 | Influence of melatonin on immunotoxicity of lead. ( Kim, JH; Kim, YO; Pyo, MY, 2000) |
| "Melatonin has been found to exhibit youth-maintaining and disease-preventing properties." | 1.31 | An age-related decline in melatonin secretion is not altered by food restriction. ( Everitt, AV; MacGibbon, MF; Walls, RS, 2001) |
| "Melatonin treatment improved the maximal relaxation of mesenteric arteries to A23187 in SHR (P < 0." | 1.31 | Vasorelaxant effects of the chronic treatment with melatonin on mesenteric artery and aorta of spontaneously hypertensive rats. ( Chulak, C; de Champlain, J; Girouard, H; Lamontagne, D; Lejossec, M, 2001) |
| "Fever is considered an important host defense response but requires significant metabolic energy." | 1.31 | Melatonin regulates energy balance and attenuates fever in Siberian hamsters. ( Bilbo, SD; Nelson, RJ, 2002) |
| "As melatonin levels have been reported to decrease with age, melatonin replacement therapy may attenuate the incidence of sudden cardiac death especially in older patients." | 1.31 | Effects of physiological and pharmacological concentrations of melatonin on ischemia-reperfusion arrhythmias in rats: can the incidence of sudden cardiac death be reduced? ( Acet, A; Olmez, E; Sahna, E, 2002) |
| "Melatonin is a neuroendocrine hormone which is currently receiving considerable attention as a treatment for jet lag, a treatment for insomnia and, by some, a possible "magic bullet" for delaying the effects of aging and preventing cancer." | 1.30 | A mathematical model of production, distribution, and metabolism of melatonin in mammalian systems. ( Blumenthal, GM; Kohn, MC; Portier, CJ, 1997) |
| "Body weights were measured weekly throughout the experiment and testes weights, spleen weights, and serum was collected at the end of the experiment." | 1.30 | Time-dependent effects of melatonin on immune measurements in male Syrian hamsters. ( Allen, GC; Beausang, LA; Champney, TH; Zannelli, M, 1998) |
| " Chronic administration of melatonin (n = 6) and taurine (n = 6) prevented increases in glomerular TGF-beta1 and fibronectin mRNAs and proteinuria without having effect on blood glucose." | 1.30 | Melatonin and taurine reduce early glomerulopathy in diabetic rats. ( Ha, H; Kim, KH; Yu, MR, 1999) |
| "Melatonin and probucol were equally effective in inhibiting the increase in myocardial TBARS as well as zinc levels, suggesting that myocardial zinc accumulation might be a protective response against adriamycin-induced oxidative stress." | 1.30 | Zinc accumulation in adriamycin-induced cardiomyopathy in rats: effects of melatonin, a cardioprotective antioxidant. ( Hayakawa, M; Hayakawa, T; Ito, T; Kaneko, S; Kawakami, K; Matsui, H; Mokuno, S; Morishima, I; Numaguchi, Y; Okumura, K; Toki, Y, 1999) |
| " These results are consistent with previous work highlighting the importance of aberrant amine production in neurological disease and demonstrate that treatments that reduce endogenous melatonin bioavailability can ameliorate experimental PD." | 1.30 | A therapeutic role for melatonin antagonism in experimental models of Parkinson's disease. ( Armstrong, SM; Willis, GL, 1999) |
| "Melatonin (MEL) is a widely used, over-the-counter sleep aid, and it has putative contraceptive, antioxidant, antiaging, and anticancer effects." | 1.30 | Maternal and developmental toxicity evaluation of melatonin administered orally to pregnant Sprague-Dawley rats. ( Jahnke, G; Marr, M; Myers, C; Price, C; Travlos, G; Wilson, R, 1999) |
| "Melatonin treatment during light exposure and on two succeeding nights blocked the stimulatory effect of light on the reproductive axis; melatonin injections limited to one night were marginally effective." | 1.29 | Sustained hormonal responses of Siberian hamsters (Phodopus sungorus) to a single longer day at weaning. ( Finley, CM; Kelly, KK; Licht, P; Spears, N; Whaling, CS; Zucker, I, 1993) |
| " The results of pharmacokinetic parameters calculated from serum melatonin showed no significant gender differences in adults." | 1.29 | Pharmacokinetics of melatonin in human sexual maturation. ( Cavallo, A; Ritschel, WA, 1996) |
| "Melatonin-treated mice received either short-term treatment on Days 1 and 2 after hemorrhage or continuous treatment throughout the study." | 1.29 | Melatonin administration following hemorrhagic shock decreases mortality from subsequent septic challenge. ( Ayala, A; Chaudry, IH; Haisken, JM; Wichmann, MW, 1996) |
| "Melatonin-treated animals showed maximum values for all these measurements during winter." | 1.28 | Effects of subcutaneous melatonin implants during long daylength on voluntary feed intake, rumen capacity and heart rate of red deer (Cervus elaphus) fed on a forage diet. ( Barry, TN; Dellow, DW; Domingue, BM; Wilson, PR, 1992) |
| "Treatment with melatonin increased the incidence of heifers pubertal by the second observation date (P less than ." | 1.28 | Effects of melatonin treatment on the attainment of puberty in heifers. ( Inskeep, EK; Tortonese, DJ, 1992) |
| " The brown adipose tissue enzyme T4 5'-deiodinase demonstrated an increased activity in the presence of NMDA, with the lowest dosage eliciting the most significant effect." | 1.28 | N-methyl-D-aspartate does not prevent effects of melatonin on the reproductive and thyroid axes of male Syrian hamsters. ( Hoover, PA; Little, JC; Reiter, RJ; Vaughan, MK, 1992) |
| "Carbaryl was administered at total doses (over 6 days) of either 50, 125 or 250 mg/kg by gastric gavage." | 1.28 | Carbaryl-induced changes in indoleamine synthesis in the pineal gland and its effects on nighttime serum melatonin concentrations. ( Attia, AM; el-Sebae, AH; Mostafa, MH; Nonaka, KO; Reiter, RJ; Soliman, SA, 1991) |
| "Melatonin levels were intermediate when dim light was accompanied by both bright light and darkness." | 1.28 | Plasma melatonin levels in Japanese quail exposed to dim light are determined by subjective interpretation of day and night, not light intensity. ( Meyer, WE; Millam, JR, 1991) |
| "Melatonin treatment advanced rutting activity, testis development and neck muscle hypertrophy by 6-8 weeks." | 1.28 | Pattern of LH and testosterone secretion of adult male fallow deer (Dama dama) during the transition into the breeding season. ( Asher, GW; Peterson, AJ, 1991) |
| "Melatonin treatment advanced the seasonal changes in scrotal circumference, liveweight, antler state and coat type compared with control stags." | 1.28 | Effects of melatonin implants on reproductive seasonality of male red deer (Cervus elaphus). ( Corson, ID; Suttie, JM; Webster, JR, 1991) |
| "Melatonin-treated animals experienced less maturational inhibition when simultaneously given a low dose of 6-MBOA-coated chow (1." | 1.28 | Reproductive responses of male Microtus montanus to photoperiod, melatonin, and 6-MBOA. ( Berger, PJ; Gower, BA, 1990) |
| "Melatonin in tissues was extracted, identified, and determined by gas chromatography-mass spectrometry (GC-MS) and/or radioimmunoassay." | 1.28 | Fluctuation of blood melatonin concentrations with age: result of changes in pineal melatonin secretion, body growth, and aging. ( Brown, GM; Hong, GX; Pang, SF; Tang, PL; Tsang, CW; Yip, PC, 1990) |
| "Melatonin treatment (but not SP exposure) significantly enhanced the reduction in pituitary, ovarian and uterine weight compared to the underfed saline-treated controls." | 1.28 | Undernutrition potentiates melatonin effects in maturing female rats. ( Nordio, M; Reiter, RJ; Sabry, I; Vaughan, MK, 1989) |
| "Melatonin-treated animals had significantly reduced testicular and seminal vesicle weights, compared with vehicle-treated control animals: serum T4 levels and the FT4I were reduced by melatonin treatment, but serum T3 and the FT3I were increased." | 1.28 | Effects of melatonin and thyroxine treatment on reproductive organs and thyroid hormone levels in male hamsters. ( Creighton, JA; Rudeen, PK, 1989) |
| "Melatonin-treated hamsters had significantly greater mean body weights than did the vehicle-treated hamsters (P less than 0." | 1.28 | Effects of daily afternoon melatonin administration on body weight and thyroid hormones in female hamsters. ( Petterborg, LJ; Rudeen, PK, 1989) |
| "Melatonin levels were not lower in females than in males, when melatonin levels were adjusted for body height." | 1.27 | Melatonin in relation to body measures, sex, age, season and the use of drugs in patients with major affective disorders and healthy subjects. ( Beck-Friis, J; Kjellman, BF; Ljunggren, JG; von Rosen, D; Wetterberg, L, 1984) |
| "Melatonin was administered in a Silastic implant inserted sc over the scapular region during the last week of June." | 1.27 | Induction of winter fur growth in mink (Mustela vison) with melatonin. ( Adair, J; Oldfield, J; Rose, J; Stormshak, F, 1984) |
| "Imipramine treatment produced a down-regulation of the Bmax for 3H-dihydroalprenolol binding to cortical beta-adrenoceptors that was not dependent upon the time of day the animals were killed." | 1.27 | Cortical beta- and alpha 2- adrenoceptor binding, hypothalamic noradrenaline and pineal melatonin concentrations measured at different times of the day after repeated treatment of rats with imipramine, zimeldine, alaproclate and amiflamine. ( Ask, AL; Fowler, CJ; Hall, H; Kelder, D; Ross, SB; Sääf, J, 1986) |
| "Melatonin was without effect on the rate of increase in size of the testis, circumference of the neck or growth and cleaning of the antlers although 1 of the treated animals failed to cast his antlers at the expected time 8 months after cleaning." | 1.27 | Cycles of antler and testicular growth in an aseasonal tropical deer (Axis axis). ( Curlewis, JD; Loudon, AS, 1988) |
| "To extend our previous experiment on anti-glucocorticoid effects of melatonin which was performed under a very special condition using young rats, we have carried out another experiment of long term administration of pineal hormone melatonin to adult female rats which were conditioned by overdose glucocorticoid." | 1.27 | Anti-glucocorticoid effects of melatonin on adult rats. ( Aoyama, H; Mori, N; Mori, W, 1987) |
| "Melatonin-treated mole rats exhibited reduction both in initial body temperature (Tbo) and in the decrease of body temperature (delta Tb) after 6 hours of exposure to cold." | 1.27 | The effect of melatonin administration and short exposures to cold on body temperature of the blind subterranean mole rat (Rodentia, Spalax ehrenberghi, Nehring). ( Beiles, A; Heth, G; Nevo, E; Pevet, P, 1986) |
| "Melatonin-treated hinds lost slightly more live weight than did controls from June to November, but their suckled calves grew throughout at a rate similar to those of control hinds." | 1.27 | Induction of early breeding in red deer (Cervus elaphus) by melatonin. ( Adam, CL; Atkinson, T; Moir, CE, 1986) |
| "Melatonin was administered intravaginally in Silastic tubing to adult and prepubertal ewes." | 1.27 | Effect of intravaginal implants of melatonin on the onset of ovarian activity in adult and prepubertal ewes. ( Nowak, R; Rodway, RG, 1985) |
| "Melatonin was estimated by RIA in samples taken at 24." | 1.26 | Reduced nocturnal melatonin secretion in chronic schizophrenia: relationship to body weight. ( Arendt, J; Crow, TJ; Ferrier, IN; Johnstone, EC, 1982) |
| " Serum testosterone levels were depressed in animals that received afternoon injections of melatonin regardless of the dosage of melatonin given in the morning." | 1.26 | Apparent dualistic effects of twice daily melatonin administration on reproductive organs in male golden hamsters. ( Rudeen, PK, 1981) |
| "Melatonin treatment prevented the atrophic responses of the testes and accessory sex organs in males and the uteri in females." | 1.26 | Prevention by melatonin of short day induced atrophy of the reproductive systems of male and female hamsters. ( Reiter, RJ; Vaughan, MK; Waring, PJ, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 110 (23.45) | 18.7374 |
| 1990's | 96 (20.47) | 18.2507 |
| 2000's | 127 (27.08) | 29.6817 |
| 2010's | 113 (24.09) | 24.3611 |
| 2020's | 23 (4.90) | 2.80 |
| Authors | Studies |
|---|---|
| El Aasar, H | 1 |
| Rashed, L | 1 |
| El Sadik, A | 1 |
| Amer, R | 1 |
| Emam, H | 1 |
| Munley, KM | 1 |
| Dutta, S | 1 |
| Jasnow, AM | 2 |
| Demas, GE | 3 |
| Chen, JY | 1 |
| Li, T | 3 |
| Wang, JL | 1 |
| Wang, ZL | 1 |
| Zhang, Y | 5 |
| Zang, LQ | 1 |
| Ma, W | 1 |
| Wu, H | 1 |
| Li, G | 1 |
| Yan, L | 1 |
| Wang, L | 4 |
| Zhao, M | 1 |
| Guan, S | 1 |
| Xu, S | 2 |
| Guo, X | 2 |
| Liu, F | 1 |
| Ji, P | 1 |
| Wusiman, A | 1 |
| Liu, G | 2 |
| Hu, S | 1 |
| Liu, X | 3 |
| Wang, Y | 6 |
| Zhang, R | 3 |
| Wei, S | 1 |
| Meth, EMS | 1 |
| Brandão, LEM | 1 |
| van Egmond, LT | 1 |
| Xue, P | 1 |
| Grip, A | 1 |
| Wu, J | 1 |
| Adan, A | 1 |
| Andersson, F | 1 |
| Pacheco, AP | 1 |
| Uvnäs-Moberg, K | 1 |
| Cedernaes, J | 1 |
| Benedict, C | 1 |
| Shrief, AI | 1 |
| Hamed, WHE | 1 |
| Mazroa, SA | 1 |
| Moustafa, AM | 1 |
| Qin, T | 1 |
| Feng, D | 1 |
| Zhou, B | 1 |
| Bai, L | 1 |
| Zhou, S | 1 |
| Du, J | 1 |
| Xu, G | 1 |
| Yin, Y | 2 |
| Hsu, LW | 1 |
| Chien, YW | 1 |
| Dehdari Ebrahimi, N | 2 |
| Sadeghi, A | 2 |
| Ala, M | 1 |
| Ebrahimi, F | 1 |
| Pakbaz, S | 1 |
| Azarpira, N | 2 |
| Shojaei-Zarghani, S | 1 |
| Shahlaee, MA | 1 |
| Taherifard, E | 1 |
| Rahimian, Z | 1 |
| Eghlidos, Z | 1 |
| Safarpour, AR | 1 |
| Yue, S | 1 |
| Zhao, D | 2 |
| Peng, C | 1 |
| Tan, C | 1 |
| Wang, Q | 2 |
| Gong, J | 1 |
| Wang, N | 1 |
| Li, H | 3 |
| Zhu, Y | 2 |
| Li, N | 2 |
| Chen, ZJ | 1 |
| Zhang, C | 2 |
| Onaolapo, AY | 1 |
| Adebisi, EO | 1 |
| Adeleye, AE | 1 |
| Olofinnade, AT | 1 |
| Onaolapo, OJ | 1 |
| Alves, ÉR | 1 |
| Ferreira, CGM | 1 |
| Silva, MVD | 1 |
| Vieira Filho, LD | 2 |
| Silva Junior, VAD | 1 |
| Melo, IMF | 1 |
| Neto, CJCL | 1 |
| Santos, LCDS | 1 |
| Teixeira, ÁAC | 2 |
| Wanderley Teixeira, V | 1 |
| Mou, J | 1 |
| Xu, J | 1 |
| Wang, Z | 4 |
| Wang, C | 1 |
| Yang, X | 2 |
| Wang, X | 3 |
| Xue, H | 1 |
| Wu, M | 1 |
| Xu, L | 1 |
| Nese, M | 1 |
| Riboli, G | 1 |
| Brighetti, G | 1 |
| Sassi, V | 1 |
| Camela, E | 1 |
| Caselli, G | 1 |
| Sassaroli, S | 1 |
| Borlimi, R | 1 |
| Aucoin, M | 1 |
| Cooley, K | 1 |
| Saunders, PR | 1 |
| Carè, J | 1 |
| Anheyer, D | 1 |
| Medina, DN | 1 |
| Cardozo, V | 1 |
| Remy, D | 1 |
| Hannan, N | 1 |
| Garber, A | 1 |
| Velayos, M | 1 |
| Muñoz-Serrano, AJ | 1 |
| Estefanía-Fernández, K | 1 |
| Sarmiento Caldas, MC | 1 |
| Moratilla Lapeña, L | 1 |
| López-Santamaría, M | 1 |
| López-Gutiérrez, JC | 1 |
| Li, J | 1 |
| Zhang, J | 1 |
| Shen, S | 1 |
| Zhang, B | 2 |
| Yu, WW | 1 |
| Toyoda, H | 1 |
| Huang, DQ | 1 |
| Le, MH | 1 |
| Nguyen, MH | 1 |
| Huang, R | 1 |
| Zhu, L | 1 |
| Wang, J | 6 |
| Xue, L | 1 |
| Liu, L | 2 |
| Yan, X | 2 |
| Huang, S | 1 |
| Li, Y | 7 |
| Xu, T | 1 |
| Li, C | 2 |
| Ji, F | 1 |
| Ming, F | 1 |
| Zhao, Y | 2 |
| Cheng, J | 1 |
| Zhao, H | 1 |
| Hong, S | 1 |
| Chen, K | 2 |
| Zhao, XA | 1 |
| Zou, L | 1 |
| Sang, D | 1 |
| Shao, H | 1 |
| Guan, X | 1 |
| Chen, X | 2 |
| Chen, Y | 4 |
| Wei, J | 1 |
| Zhu, C | 1 |
| Wu, C | 1 |
| Moore, HB | 1 |
| Barrett, CD | 1 |
| Moore, EE | 1 |
| Jhunjhunwala, R | 1 |
| McIntyre, RC | 1 |
| Moore, PK | 1 |
| Hajizadeh, N | 1 |
| Talmor, DS | 1 |
| Sauaia, A | 1 |
| Yaffe, MB | 1 |
| Liu, C | 3 |
| Lin, Y | 1 |
| Dong, Y | 1 |
| Wu, Y | 1 |
| Bao, Y | 1 |
| Yan, H | 2 |
| Ma, J | 1 |
| Fernández-Cuadros, ME | 1 |
| Albaladejo-Florín, MJ | 1 |
| Álava-Rabasa, S | 1 |
| Usandizaga-Elio, I | 1 |
| Martinez-Quintanilla Jimenez, D | 1 |
| Peña-Lora, D | 1 |
| Neira-Borrajo, I | 1 |
| López-Muñoz, MJ | 1 |
| Rodríguez-de-Cía, J | 1 |
| Pérez-Moro, OS | 1 |
| Abdallah, M | 1 |
| Alsaleh, H | 1 |
| Baradwan, A | 1 |
| Alfawares, R | 1 |
| Alobaid, A | 1 |
| Rasheed, A | 1 |
| Soliman, I | 1 |
| Wendel Garcia, PD | 1 |
| Fumeaux, T | 1 |
| Guerci, P | 1 |
| Heuberger, DM | 1 |
| Montomoli, J | 2 |
| Roche-Campo, F | 1 |
| Schuepbach, RA | 1 |
| Hilty, MP | 1 |
| Poloni, TE | 1 |
| Carlos, AF | 1 |
| Cairati, M | 1 |
| Cutaia, C | 1 |
| Medici, V | 1 |
| Marelli, E | 1 |
| Ferrari, D | 1 |
| Galli, A | 1 |
| Bognetti, P | 1 |
| Davin, A | 1 |
| Cirrincione, A | 1 |
| Ceretti, A | 1 |
| Cereda, C | 1 |
| Ceroni, M | 1 |
| Tronconi, L | 1 |
| Vitali, S | 1 |
| Guaita, A | 1 |
| Leeds, JS | 1 |
| Raviprakash, V | 1 |
| Jacques, T | 1 |
| Scanlon, N | 1 |
| Cundall, J | 1 |
| Leeds, CM | 1 |
| Riva, A | 1 |
| Gray, EH | 1 |
| Azarian, S | 1 |
| Zamalloa, A | 1 |
| McPhail, MJW | 1 |
| Vincent, RP | 1 |
| Williams, R | 1 |
| Chokshi, S | 1 |
| Patel, VC | 1 |
| Edwards, LA | 1 |
| Alqarawi, W | 1 |
| Birnie, DH | 1 |
| Golian, M | 1 |
| Nair, GM | 1 |
| Nery, PB | 1 |
| Klein, A | 1 |
| Davis, DR | 1 |
| Sadek, MM | 1 |
| Neilipovitz, D | 1 |
| Johnson, CB | 1 |
| Green, MS | 1 |
| Redpath, C | 1 |
| Miller, DC | 1 |
| Beamer, P | 1 |
| Billheimer, D | 1 |
| Subbian, V | 1 |
| Sorooshian, A | 1 |
| Campbell, BS | 1 |
| Mosier, JM | 1 |
| Novaretti, JV | 1 |
| Astur, DC | 1 |
| Cavalcante, ELB | 1 |
| Kaleka, CC | 1 |
| Amaro, JT | 1 |
| Cohen, M | 1 |
| Huang, W | 1 |
| Ling, Y | 1 |
| Qian, ZP | 1 |
| Zhang, YY | 1 |
| Huang, D | 1 |
| Xu, SB | 1 |
| Liu, XH | 1 |
| Xia, L | 1 |
| Yang, Y | 3 |
| Lu, SH | 1 |
| Lu, HZ | 1 |
| Ma, JX | 1 |
| Tang, S | 1 |
| Li, CM | 1 |
| Wan, J | 1 |
| Wang, JF | 1 |
| Ma, JQ | 1 |
| Luo, JJ | 1 |
| Chen, HY | 4 |
| Mi, SL | 1 |
| Chen, SY | 1 |
| Su, YG | 1 |
| Ge, JB | 1 |
| Milheiro, SA | 1 |
| Gonçalves, J | 1 |
| Lopes, RMRM | 1 |
| Madureira, M | 1 |
| Lobo, L | 1 |
| Lopes, A | 1 |
| Nogueira, F | 1 |
| Fontinha, D | 1 |
| Prudêncio, M | 1 |
| M Piedade, MF | 1 |
| Pinto, SN | 1 |
| Florindo, PR | 1 |
| Moreira, R | 1 |
| Castillo-Lora, J | 1 |
| Delley, MF | 1 |
| Laga, SM | 1 |
| Mayer, JM | 1 |
| Sutjarit, N | 1 |
| Thongon, N | 1 |
| Weerachayaphorn, J | 1 |
| Piyachaturawat, P | 1 |
| Suksamrarn, A | 1 |
| Suksen, K | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Traditional Chinese Medicine Department of Xin Qiao Hospital[NCT02619266] | Phase 2/Phase 3 | 160 participants (Anticipated) | Interventional | 2015-12-31 | Recruiting | ||
| A Randomized Clinical Trial of Melatonin Versus Placebo and the Effect on Appetite in Advanced Cancer Patients[NCT00513357] | Phase 3 | 82 participants (Actual) | Interventional | 2006-06-30 | Completed | ||
| Melatonin and Essential Arterial Hypertension[NCT05257291] | Phase 2 | 23 participants (Actual) | Interventional | 2018-02-02 | Active, not recruiting | ||
| A Pilot, Open-label Study to Evaluate the Effects of a Prostate Health Formulation on Scores Attained From the International Prostate Symptom Score (I-PSS) Questionnaire Among Overall Healthy Male Participants Who Report Lower Urinary Tract Complaints[NCT02886832] | 30 participants (Anticipated) | Interventional | 2016-09-21 | Completed | |||
| Phase IV Study of Ramelteon as an Adjunct Therapy in Non-Diabetic Patients With Schizophrenia[NCT00595504] | Phase 4 | 25 participants (Actual) | Interventional | 2008-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Difference in ESAS (Edmonton Symptom Assessment Scale) assessment scores of appetite (symptom) from baseline evaluation [± 3 days] to 4 week evaluation [± 3 days], where the severity at the time of assessment is rated from 0 to 10 on a numerical scale; with 0 meaning that the symptom is absent and 10 that it is the worst possible severity. (NCT00513357)
Timeframe: Baseline and at 4 weeks
| Intervention | units on a scale (Mean) |
|---|---|
| Melatonin | -0.83 |
| Placebo | -1.19 |
A comparison between the ramelteon group and the placebo group of change in abdominal fat measured by a DEXA scan, assessed at Baseline and Week 8. (NCT00595504)
Timeframe: Baseline and Week 8
| Intervention | g (Mean) |
|---|---|
| Ramelteon | 3934.86 |
| Placebo (Sugar Pill) | 5120.92 |
A comparison between the ramelteon group and the placebo group of change in insulin resistance measured by the homeostatic model assessment of insulin resistance (HOMA-IR), assessed at Baseline and Week 8. (NCT00595504)
Timeframe: Baseline and Week 8
| Intervention | HOMA score (Mean) |
|---|---|
| Ramelteon | 2.4 |
| Placebo (Sugar Pill) | 2.36 |
A comparison between the ramelteon group and the placebo group in change in waist circumference (measured in cm) measured at Baseline and Week 8. (NCT00595504)
Timeframe: Baseline and Week 8
| Intervention | cm (Mean) |
|---|---|
| Ramelteon | 106.09 |
| Placebo (Sugar Pill) | 108.37 |
16 reviews available for melatonin and Body Weight
| Article | Year |
|---|---|
Protective effects of melatonin against oxidative stress induced by metabolic disorders in the male reproductive system: a systematic review and meta-analysis of rodent models.
Topics: Animals; Body Weight; Diabetes Mellitus; Hyperthyroidism; Infertility, Male; Male; Melatonin; Metabo | 2023 |
Protective effects of exogenous melatonin therapy against oxidative stress to male reproductive tissue caused by anti-cancer chemical and radiation therapy: a systematic review and meta-analysis of animal studies.
Topics: Animals; Antioxidants; Body Weight; Humans; Iodine Radioisotopes; Male; Melatonin; Mice; Oxidative S | 2023 |
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; | 2022 |
A unifying hypothesis for control of body weight and reproduction in seasonally breeding mammals.
Topics: Adaptation, Physiological; Animals; Appetite Regulation; Body Weight; Chronobiology Phenomena; Energ | 2019 |
Elucidating the Regulatory Role of Melatonin in Brown, White, and Beige Adipocytes.
Topics: Adipocytes, Beige; Adipocytes, Brown; Adipocytes, White; Adipogenesis; Adiposity; Animals; Body Weig | 2020 |
Role of Melatonin in Body Weight: A Systematic Review and Meta-Analysis.
Topics: Body Weight; Humans; Melatonin; Randomized Controlled Trials as Topic | 2017 |
Role of melatonin in metabolic regulation.
Topics: Animals; Blood Pressure; Body Weight; Carbohydrate Metabolism; Circadian Rhythm; Humans; Hyperlipide | 2009 |
Molecular pathways involved in seasonal body weight and reproductive responses governed by melatonin.
Topics: Animals; Body Weight; Circadian Rhythm; Humans; Hypothalamus; Melatonin; Pituitary Gland; Reproducti | 2012 |
Melatonin and the metabolic syndrome: a tool for effective therapy in obesity-associated abnormalities?
Topics: Body Weight; Energy Metabolism; Humans; Insulin Resistance; Melatonin; Metabolic Syndrome; Obesity | 2012 |
Therapeutic perspectives for melatonin agonists and antagonists.
Topics: Animals; Anxiety; Body Weight; Brain; Cerebrovascular Circulation; Chronobiology Disorders; Circadia | 2003 |
Photoperiodic programming of body weight through the neuroendocrine hypothalamus.
Topics: Animals; Body Weight; Cricetinae; Eating; Energy Metabolism; Humans; Hypothalamus; Leptin; Mammals; | 2003 |
Appetite regulation and seasonality: implications for obesity.
Topics: Animals; Appetite Regulation; Body Weight; Energy Metabolism; Humans; Leptin; Melatonin; Obesity; Ph | 2004 |
The timed infusion paradigm for melatonin delivery: what has it taught us about the melatonin signal, its reception, and the photoperiodic control of seasonal responses?
Topics: Animals; Body Weight; Brain; Cricetinae; Female; Injections; Male; Melatonin; Mesocricetus; Phodopus | 1993 |
The regulation of body weight: lessons from the seasonal animal.
Topics: Animals; Body Weight; Cricetinae; Eating; Feeding Behavior; Homeostasis; Humans; Hypothalamus; Melat | 2001 |
Disturbances of appetite and weight regulation in seasonal affective disorder.
Topics: Body Weight; Depression; Dietary Carbohydrates; Feeding and Eating Disorders; Feeding Behavior; Fema | 1987 |
Photoperiodic control of seasonal body weight cycles in hamsters.
Topics: Adipose Tissue; Animals; Arvicolinae; Body Weight; Brain Mapping; Circadian Rhythm; Cricetinae; Diet | 1985 |
15 trials available for melatonin and Body Weight
| Article | Year |
|---|---|
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; | 2022 |
Melatonin Supplementation and Anthropometric Indices: A Randomized Double-Blind Controlled Clinical Trial.
Topics: Adult; Anthropometry; Body Composition; Body Mass Index; Body Weight; Diet, Reducing; Double-Blind M | 2021 |
Melatonin for Reducing Weight Gain Following Administration of Atypical Antipsychotic Olanzapine for Adolescents with Bipolar Disorder: A Randomized, Double-Blind, Placebo-Controlled Trial.
Topics: Adolescent; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Body Weight; | 2017 |
Effect of a photoperiodic green light programme during incubation on embryo development and hatch process.
Topics: Animals; Body Weight; Chick Embryo; Chickens; Circadian Rhythm; Corticosterone; Embryonic Developmen | 2018 |
Melatonin Increases Brown Adipose Tissue Volume and Activity in Patients With Melatonin Deficiency: A Proof-of-Concept Study.
Topics: Adipose Tissue, Brown; Body Weight; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Energy Metaboli | 2019 |
Effects of melatonin on appetite and other symptoms in patients with advanced cancer and cachexia: a double-blind placebo-controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Antioxidants; Appetite; Body Weight; Cachexia; Depression; Double-Bl | 2013 |
Effects of melatonin on appetite and other symptoms in patients with advanced cancer and cachexia: a double-blind placebo-controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Antioxidants; Appetite; Body Weight; Cachexia; Depression; Double-Bl | 2013 |
Effects of melatonin on appetite and other symptoms in patients with advanced cancer and cachexia: a double-blind placebo-controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Antioxidants; Appetite; Body Weight; Cachexia; Depression; Double-Bl | 2013 |
Effects of melatonin on appetite and other symptoms in patients with advanced cancer and cachexia: a double-blind placebo-controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Antioxidants; Appetite; Body Weight; Cachexia; Depression; Double-Bl | 2013 |
Effects of exogenous melatonin and photoperiod on sexual maturation in pullets.
Topics: Adipose Tissue; Animal Feed; Animals; Body Weight; Chickens; Dietary Supplements; Female; Melatonin; | 2016 |
The reproductive performance of female goats treated with melatonin is not improved after introduction to bucks displaying springtime sexual activity if these does are experiencing decreasing body weight/condition score.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Antioxidants; Blood Glucose; Body | 2017 |
The use of melatonin and progestagen-eCG to initiate reproductive activity in prepuberal Awassi ewe lambs.
Topics: Animals; Body Weight; Chorionic Gonadotropin; Estrus; Female; Fertilization; Melatonin; Progestins; | 2011 |
Effects of nutritional cues on the duration of the winter anovulatory phase and on associated hormone levels in adult female Welsh pony horses (Equus caballus).
Topics: Adiposity; Animals; Anovulation; Blood Glucose; Body Weight; Caloric Restriction; Circadian Rhythm; | 2011 |
Impact of fish oil and melatonin on cachexia in patients with advanced gastrointestinal cancer: a randomized pilot study.
Topics: Aged; Aged, 80 and over; Antioxidants; Body Weight; Cachexia; Cross-Over Studies; Cytokines; Dietary | 2005 |
Changes of sleep architecture, spectral composition of sleep EEG, the nocturnal secretion of cortisol, ACTH, GH, prolactin, melatonin, ghrelin, and leptin, and the DEX-CRH test in depressed patients during treatment with mirtazapine.
Topics: Adrenocorticotropic Hormone; Adult; Animals; Antidepressive Agents, Tricyclic; Area Under Curve; Bod | 2006 |
Serum thyroid hormones and performance of offspring in ewes receiving propylthiouracil with or without melatonin.
Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Estrous Cycle; Female; Hypothyroidism; Melat | 2007 |
Hormone levels of world class cyclists during the Tour of Spain stage race.
Topics: Adult; Bicycling; Body Weight; Circadian Rhythm; Exercise; Follicle Stimulating Hormone; Hormones; H | 2001 |
Negative effects of melatonin on depression.
Topics: Adult; Anger; Anxiety; Body Temperature; Body Weight; Calcium; Clinical Trials as Topic; Depression; | 1976 |
439 other studies available for melatonin and Body Weight
| Article | Year |
|---|---|
The role of the adipose tissue-derived mesenchymal stem cells enriched with melatonin in pancreatic cellular regeneration.
Topics: Animals; Blood Glucose; Body Weight; Caspase 3; Diabetes Mellitus, Experimental; Insulin; Insulin-Se | 2022 |
Adrenal MT
Topics: Aggression; Animals; Body Weight; Cricetinae; Male; Melatonin; Phodopus; Photoperiod; Receptors, Mel | 2022 |
Protective Effects and Mechanisms of Melatonin on Stress Myocardial Injury in Rats.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blood Glucose; Body Weight; Caspase 3; Creatine Kina | 2022 |
Melatonin promotes the growth and development of lambs by increasing growth hormone and testosterone, targeting on apoptosis signaling pathway and intestinal microflora.
Topics: Animals; Apoptosis; Body Weight; Female; Gastrointestinal Microbiome; Growth Hormone; Human Growth H | 2022 |
Melatonin protects against body weight gain induced by sleep deprivation in mice.
Topics: Animals; Body Weight; Circadian Rhythm; Melatonin; Mice; Obesity; Sleep; Sleep Deprivation; Weight G | 2022 |
A weighted blanket increases pre-sleep salivary concentrations of melatonin in young, healthy adults.
Topics: Adult; Body Weight; Circadian Rhythm; Cross-Over Studies; Female; Humans; Male; Melatonin; Oxytocin; | 2023 |
Histological study of the role of CD34+ stem cells and mast cells in cyclophosphamide-induced thymic injury in rats and the possible attenuating role of melatonin.
Topics: Animals; Antioxidants; Body Weight; Cyclophosphamide; Male; Mast Cells; Melatonin; Rats | 2023 |
Melatonin attenuates lipopolysaccharide-induced immune dysfunction in dendritic cells.
Topics: Acute Lung Injury; Animals; Body Weight; Cytokines; Dendritic Cells; Interleukin-12; Interleukin-17; | 2023 |
Effects of Melatonin Supplementation on Lipid Metabolism and Body Fat Accumulation in Ovariectomized Rats.
Topics: Adipose Tissue; Animals; Body Weight; Dietary Supplements; Fatty Acids; Female; Fibronectins; Humans | 2023 |
Effects of theabrownin on serum metabolites and gut microbiome in rats with a high-sugar diet.
Topics: Animals; Bacteria; Body Weight; Catechin; Cecum; Cholic Acid; Dietary Sugars; Gastrointestinal Micro | 2019 |
Melatonin protects against Epirubicin-induced ovarian damage.
Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Body Weight; Caspase 3; Caspase 9; Endoplasmic Reti | 2020 |
Dietary Melatonin Protects Against Behavioural, Metabolic, Oxidative, and Organ Morphological Changes in Mice that are Fed High-Fat, High- Sugar Diet.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Brain; Diet, High-Fat; Dietary Sugars; Eating; Ex | 2020 |
Protective action of melatonin on diabetic rat testis at cellular, hormonal and immunohistochemical levels.
Topics: Animals; Antioxidants; Body Weight; Diabetes Mellitus, Experimental; Lipid Peroxidation; Male; Melat | 2020 |
Effects of photoperiod on morphology and function in testis and epididymis of Cricetulus barabensis.
Topics: Animals; Apoptosis; Autophagy-Related Proteins; Body Weight; Cell Nucleus; Cricetulus; DNA Fragmenta | 2021 |
The effects of melatonin daily supplementation to aged rats on the ability to withstand cold, thermoregulation and body weight.
Topics: Animals; Body Temperature Regulation; Body Weight; Cold Temperature; Cold-Shock Response; Dietary Su | 2021 |
Luffa operculata at a late period of gestation dysregulates melatonin and cytokines interfering with weight of dams and their male offspring.
Topics: Administration, Oral; Adrenocorticotropic Hormone; Animals; Animals, Newborn; Behavior, Animal; Body | 2021 |
Agomelatine reduces circulating triacylglycerides and hepatic steatosis in fructose-treated rats.
Topics: Acetamides; Animals; Apolipoproteins B; Body Weight; Carrier Proteins; Energy Intake; Fatty Liver; F | 2021 |
Melatonin Alleviated Potassium Dichromate-Induced Oxidative Stress and Reprotoxicity in Male Rats.
Topics: Animals; Antioxidants; Body Weight; Catalase; Chromatography, High Pressure Liquid; Glutathione; Gon | 2021 |
Involvement of endometrial IGF-1R/IGF-1/Bcl-2 pathways in experimental polycystic ovary syndrome: Identification of the regulatory effect of melatonin.
Topics: Animals; Body Weight; Endometrium; Female; Insulin-Like Growth Factor I; Melatonin; Ovary; Polycysti | 2021 |
Prolactin modulates luteal activity in the short-nosed fruit bat, Cynopterus sphinx during delayed embryonic development.
Topics: Animals; Body Weight; Chiroptera; Cholesterol; Corpus Luteum; Embryonic Development; Estradiol; Fema | 2017 |
Protective effects of melatonin on long-term administration of fluoxetine in rats.
Topics: Animals; Antioxidants; Body Weight; Drug-Related Side Effects and Adverse Reactions; Erythrocyte Cou | 2017 |
High-fat diet-induced plasma protein and liver changes in obese rats can be attenuated by melatonin supplementation.
Topics: alpha 1-Antitrypsin; Animals; Biomarkers; Blood Glucose; Blood Proteins; Body Weight; Complement C4; | 2017 |
Oral Supplementation of Melatonin Protects against Fibromyalgia-Related Skeletal Muscle Alterations in Reserpine-Induced Myalgia Rats.
Topics: Administration, Oral; Analysis of Variance; Animals; Antioxidants; Body Weight; Disease Models, Anim | 2017 |
Short photoperiod reverses obesity in Siberian hamsters via sympathetically induced lipolysis and Browning in adipose tissue.
Topics: Adipose Tissue, Brown; Adipose Tissue, White; Animals; Body Weight; Brain; Colon; Cricetinae; Dopami | 2018 |
Melatonin ameliorates restraint stress-induced oxidative stress and apoptosis in testicular cells via NF-κB/iNOS and Nrf2/ HO-1 signaling pathway.
Topics: Animals; Apoptosis; Body Weight; Corticosterone; Heme Oxygenase-1; Male; Melatonin; Mice; NF-E2-Rela | 2017 |
Melatonin alters amino acid metabolism and inflammatory responses in colitis mice.
Topics: Amino Acids; Animals; Anti-Inflammatory Agents; Body Weight; Colitis; Dextran Sulfate; Disease Model | 2017 |
Melatonin Prevents the Harmful Effects of Obesity on the Brain, Including at the Behavioral Level.
Topics: Animals; Autophagy; Behavior, Animal; Biomarkers; Body Weight; Brain; Cytokines; Endoplasmic Reticul | 2018 |
Features of the daily rhythms of blood melatonin and glucose in goats during different natural photoperiod.
Topics: Analysis of Variance; Animals; Blood Glucose; Body Weight; Circadian Rhythm; Darkness; Female; Goats | 2018 |
Reproductive responses to sexually active buck of does treated with melatonin when body weight/body condition is increasing or decreasing.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Body Composition; Body Weight; Die | 2018 |
Damaging Effects of Bisphenol A on the Kidney and the Protection by Melatonin: Emerging Evidences from In Vivo and In Vitro Studies.
Topics: Animals; Benzhydryl Compounds; Body Weight; Kidney; Kidney Function Tests; Male; Melatonin; Mitochon | 2018 |
Melatonin prevents and ameliorates lead-induced gonadotoxicity through antioxidative and hormonal mechanisms.
Topics: Animals; Antioxidants; Body Weight; Gonadotropin-Releasing Hormone; Gonadotropins, Pituitary; Lead; | 2018 |
Protective effect of melatonin versus montelukast in cisplatin-induced seminiferous tubule damage in rats.
Topics: Acetates; Animals; Antineoplastic Agents; Antioxidants; Body Weight; Cisplatin; Cyclopropanes; Drug | 2018 |
Potential therapeutic role of melatonin on STZ-induced diabetic central neuropathy: A biochemical, histopathological, immunohistochemical and ultrastructural study.
Topics: Animals; Blood Glucose; Body Weight; Brain; Diabetes Mellitus, Experimental; Immunohistochemistry; I | 2018 |
Protective Role of Melatonin in Streptozotocin Induced Pancreatic Damages in Diabetic Wistar Rat.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Hyperglycemia; I | 2018 |
Redox homeostasis in a rodent model of circadian disruption: Effect of melatonin supplementation.
Topics: Animals; Antioxidants; Biomarkers; Blood Proteins; Body Weight; Cell Membrane; Circadian Rhythm; Die | 2019 |
Melatonin attenuates cisplatin-induced acute kidney injury in rats via induction of anti-aging protein, Klotho.
Topics: Acute Kidney Injury; Animals; Antineoplastic Agents; Apoptosis; Body Weight; Caspase 3; Cisplatin; G | 2019 |
Rumen-Protected 5-Hydroxytryptophan Improves Sheep Melatonin Synthesis in the Pineal Gland and Intestinal Tract.
Topics: 5-Hydroxytryptophan; Acetylserotonin O-Methyltransferase; Animals; Aromatic-L-Amino-Acid Decarboxyla | 2019 |
[Gender-specific effects of neonatal administration of melatonin on lifespan and age-associated patholgy in 129/Sv mice.]
Topics: Animals; Antioxidants; Body Weight; Child; Female; Humans; Infant, Newborn; Longevity; Male; Melaton | 2019 |
TSH restores a summer phenotype in photoinhibited mammals via the RF-amides RFRP3 and kisspeptin.
Topics: Animals; Body Weight; Cricetinae; Female; Gene Expression; Hypothalamus; Immunohistochemistry; In Si | 2013 |
Effect of melatonin supplementation on pregnancy outcome in Wistar-Kyoto and Sprague-Dawley rats.
Topics: Animals; Body Weight; Female; Litter Size; Melatonin; Pregnancy; Pregnancy Outcome; Pregnancy, Anima | 2013 |
Therapeutic approaches of melatonin in microwave radiations-induced oxidative stress-mediated toxicity on male fertility pattern of Wistar rats.
Topics: Animals; Apoptosis; Body Weight; DNA Damage; Fertility; L-Lactate Dehydrogenase; Male; Malondialdehy | 2014 |
Disruption of circadian rhythms due to chronic constant light leads to depressive and anxiety-like behaviors in the rat.
Topics: Analysis of Variance; Animals; Anxiety; Body Weight; Cell Count; Chronobiology Disorders; Corticoste | 2013 |
Photoperiod can entrain circannual rhythms in pinealectomized European hamsters.
Topics: Animals; Body Temperature; Body Weight; Cricetinae; Data Interpretation, Statistical; Light; Male; M | 2013 |
Agomelatine in the tree shrew model of depression: effects on stress-induced nocturnal hyperthermia and hormonal status.
Topics: Acetamides; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Body Temperatu | 2014 |
Melatonin attenuates the effects of sub-acute administration of lead on kidneys in rats without altering the lead-induced reduction in nitric oxide.
Topics: Animals; Body Weight; Injections, Intraperitoneal; Kidney; Male; Melatonin; Nitric Oxide; Organ Size | 2013 |
Melatonin induces browning of inguinal white adipose tissue in Zucker diabetic fatty rats.
Topics: Adipose Tissue, Brown; Adipose Tissue, White; Animals; Body Weight; Male; Melatonin; Motor Activity; | 2013 |
Blood pressure reducing effects of piromelatine and melatonin in spontaneously hypertensive rats.
Topics: Adiponectin; Animals; Blood Glucose; Blood Pressure; Body Weight; Eating; Indoles; Insulin; Male; Me | 2013 |
The effect of melatonin on acetylsalicylic acid-induced kidney and testis damage.
Topics: Animals; Aspirin; Blood Urea Nitrogen; Body Weight; Catalase; Creatine; Glutathione; Glutathione Per | 2014 |
Influence of melatonin receptor signalling on parameters involved in blood glucose regulation.
Topics: Analysis of Variance; Animals; Blood Glucose; Body Weight; Cell Line, Tumor; Female; Glucagon; Gluco | 2014 |
Melatonin attenuates dextran sodium sulfate induced colitis with sleep deprivation: possible mechanism by microarray analysis.
Topics: Animals; Body Weight; Colitis; Colon; Dextran Sulfate; DNA; Gene Expression Regulation; Melatonin; M | 2014 |
Treatment with melatonin after status epilepticus attenuates seizure activity and neuronal damage but does not prevent the disturbance in diurnal rhythms and behavioral alterations in spontaneously hypertensive rats in kainate model of temporal lobe epile
Topics: Animals; Antioxidants; Behavior, Animal; Blood Pressure; Body Weight; Brain; Circadian Rhythm; Disea | 2014 |
Effects of melatonin on aluminium-induced neurobehavioral and neurochemical changes in aging rats.
Topics: Acetylcholinesterase; Aging; Aluminum; Animals; Behavior, Animal; Body Weight; Brain; Catalase; Glut | 2014 |
Anticontractile activity of perivascular fat in obese mice and the effect of long-term treatment with melatonin.
Topics: Adiponectin; Adipose Tissue; Animals; Antioxidants; Body Weight; Hypoxia; Inflammation; Male; Melato | 2014 |
NADPH oxidase inhibitor, apocynin, improves renal glutathione status in Zucker diabetic fatty rats: a comparison with melatonin.
Topics: Acetophenones; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Enzyme Inhibito | 2014 |
Rapidly alternating photoperiods disrupt central and peripheral rhythmicity and decrease plasma glucose, but do not affect glucose tolerance or insulin secretion in sheep.
Topics: Animals; Biomarkers; Blood Glucose; Body Temperature Regulation; Body Weight; Chronobiology Disorder | 2014 |
Melatonin prevents neonatal dexamethasone induced programmed hypertension: histone deacetylase inhibition.
Topics: Animals; Animals, Newborn; Blood Pressure; Body Weight; Dexamethasone; Gene Expression Regulation; H | 2014 |
Short-term melatonin consumption protects the heart of obese rats independent of body weight change and visceral adiposity.
Topics: Animals; Body Weight; Heart; Intra-Abdominal Fat; Melatonin; Obesity; Rats | 2014 |
Photoperiodic regulation of melatonin membrane receptor (MT1R) expression and steroidogenesis in testis of adult golden hamster, Mesocricetus auratus.
Topics: Animals; Body Weight; Cricetinae; Gene Expression Regulation; Male; Melatonin; Mesocricetus; Organ S | 2014 |
Effects of antioxidant agents against cyclosporine-induced hepatotoxicity.
Topics: Alanine Transaminase; Alkaline Phosphatase; Allopurinol; Animals; Antioxidants; Aspartate Aminotrans | 2015 |
Melatonin antagonizes Mn-induced oxidative injury through the activation of keap1-Nrf2-ARE signaling pathway in the striatum of mice.
Topics: Adaptor Proteins, Signal Transducing; Animals; Antioxidant Response Elements; Antioxidants; Apoptosi | 2015 |
Dietary DHA during development affects depression-like behaviors and biomarkers that emerge after puberty in adolescent rats.
Topics: Animals; Behavior, Animal; Biomarkers; Body Weight; Brain; Brain-Derived Neurotrophic Factor; Depres | 2015 |
Consequences of lethal-whole-body gamma radiation and possible ameliorative role of melatonin.
Topics: Animals; Antioxidants; Apoptosis; Body Weight; Caspase 3; Catalase; Gamma Rays; Gene Expression; Glu | 2014 |
Immunohistochemical distribution of leptin in kidney tissues of melatonin treated diabetic rats.
Topics: Animals; Antioxidants; Body Weight; Diabetes Mellitus, Experimental; Immunohistochemistry; Kidney; L | 2015 |
Melatonin improves experimental colitis with sleep deprivation.
Topics: Animals; Body Weight; Colitis; Cytokines; Disease Models, Animal; Gene Expression Profiling; Inflamm | 2015 |
An intact dorsomedial posterior arcuate nucleus is not necessary for photoperiodic responses in Siberian hamsters.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Body Weight; Circadian Rhythm; Cricetinae; Eating; Energy | 2015 |
Melatonin administration enhances the reproductive capacity of young rams under a southern Mediterranean environment.
Topics: Aging; Animals; Body Weight; Fertility; Libido; Male; Melatonin; Reproduction; Scrotum; Seasons; Sem | 2015 |
Melatonin counteracts changes in hypothalamic gene expression of signals regulating feeding behavior in high-fat fed rats.
Topics: Animals; Body Weight; Diet, High-Fat; Feeding Behavior; Gene Expression; Hypothalamus; Male; Melaton | 2015 |
Transcutaneous vagus nerve stimulation induces tidal melatonin secretion and has an antidiabetic effect in Zucker fatty rats.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Disease Models, Animal; Eating; Male | 2015 |
Melatonin prevents hyperglycemia in a model of sleep apnea.
Topics: Acetylcysteine; Animals; Antioxidants; Blood Glucose; Body Weight; Cholesterol; Disease Models, Anim | 2015 |
Protective effects of melatonin against 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced cardiac injury in rats.
Topics: Animals; Body Weight; Cytoprotection; Electrocardiography; Environmental Pollutants; Heart Injuries; | 2015 |
Antioxidant Treatments Recover the Alteration of Auditory-Evoked Potentials and Reduce Morphological Damage in the Inferior Colliculus after Perinatal Asphyxia in Rat.
Topics: Animals; Animals, Newborn; Antioxidants; Astrocytes; Body Weight; Disease Models, Animal; Docosahexa | 2016 |
Role of melatonin in mitigating chemotherapy-induced testicular dysfunction in Wistar rats.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Bleomycin; Body Weight; Cispl | 2016 |
Effects of vitamin E and melatonin on serum testosterone level in sleep deprived Wistar rats.
Topics: Animals; Body Weight; Corticosterone; Male; Malondialdehyde; Melatonin; Organ Size; Oxidative Stress | 2014 |
Melatonin, quercetin and resveratrol attenuates oxidative hepatocellular injury in streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Biomarkers; Blood Glucose; Body Weight; Catalase; Diabetes Complications; Dia | 2015 |
Influence of Melatonin on the Proliferative and Apoptotic Responses of the Prostate under Normal and Hyperglycemic Conditions.
Topics: Animals; Apoptosis; Blood Glucose; Body Weight; Cell Line; Cell Line, Tumor; Cell Proliferation; Cel | 2015 |
Fetal undernutrition is associated with perinatal sex-dependent alterations in oxidative status.
Topics: Animals; Animals, Newborn; Antioxidants; Biomarkers; Blood Pressure; Body Weight; Catalase; Disease | 2015 |
Effect of 2-deoxy-D-glucose induced metabolic stress on testicular steroidogenesis and antioxidant status in golden hamster, Mesocricetus auratus: Role of photoperiod.
Topics: Animals; Antioxidants; Body Weight; Catalase; Corticosterone; Cricetinae; Deoxyglucose; Glutathione | 2015 |
Comparison of the Protective Effects of Melatonin and Silymarin Against Gentamicin-Induced Nephrotoxicity in Rats.
Topics: Acute Kidney Injury; Animals; Antioxidants; Body Weight; Creatinine; Gentamicins; Glutathione; Kidne | 2016 |
Photoperiod- and Triiodothyronine-dependent Regulation of Reproductive Neuropeptides, Proinflammatory Cytokines, and Peripheral Physiology in Siberian Hamsters (Phodopus sungorus).
Topics: Animals; Body Weight; Circadian Rhythm; Cricetinae; Cytokines; Gonads; Hypothalamus; Inflammation; M | 2016 |
Klokwerk + study protocol: An observational study to the effects of night-shift work on body weight and infection susceptibility and the mechanisms underlying these health effects.
Topics: Adolescent; Adult; Body Weight; Circadian Rhythm; Disease Susceptibility; Exercise; Health Personnel | 2016 |
Melatonin modulates adiponectin expression on murine colitis with sleep deprivation.
Topics: Adiponectin; Animals; Antibodies; Body Weight; Colitis; Cytokines; Enzyme-Linked Immunosorbent Assay | 2016 |
Melatonin produces a rapid onset and prolonged efficacy in reducing depression-like behaviors in adult rats exposed to chronic unpredictable mild stress.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Body Weight; Depression; Disease Models, Animal; M | 2017 |
Effects of melatonin in rats in the initial third stage of pregnancy exposed to sub-lethal doses of herbicides.
Topics: Animals; Body Weight; Environmental Exposure; Female; Glycine; Glyphosate; Herbicides; Lipid Peroxid | 2017 |
[The bone tissue remodeling in young and adult rats in conditions of alimentary deprivation].
Topics: Aging; Alkaline Phosphatase; Animals; Body Weight; Bone and Bones; Bone Remodeling; Caloric Restrict | 2008 |
We are in the dark here: induction of depression- and anxiety-like behaviours in the diurnal fat sand rat, by short daylight or melatonin injections.
Topics: Aggression; Animals; Anxiety; Body Weight; Data Interpretation, Statistical; Depression; Food Prefer | 2009 |
Effects of cold exposure, exogenous melatonin and short-day treatment on the weight-regulation and body temperature of the Siberian hamster (Phodopus sungorus).
Topics: Acclimatization; Animals; Body Temperature; Body Weight; Cricetinae; Female; Ghrelin; Insulin; Lepti | 2008 |
Strategies to control antipsychotic-induced weight gain.
Topics: Anti-Obesity Agents; Antipsychotic Agents; Awareness; Body Weight; Bupropion; Clinical Competence; F | 2008 |
Protective effects of melatonin and aminoguanidine on the cornea in streptozotocin-induced diabetic rats.
Topics: Administration, Oral; Animals; Antioxidants; Blood Glucose; Body Weight; Corneal Diseases; Diabetes | 2008 |
Melatonin attenuates lipopolysaccharide-induced acute lung inflammation in sleep-deprived mice.
Topics: Analysis of Variance; Animals; Body Weight; Histocytochemistry; In Situ Nick-End Labeling; Lipid Per | 2009 |
The effect of seasonality on normal haematological and innate immune parameters of rainbow trout Oncorhynchus mykiss L.
Topics: Animals; Body Weight; Circadian Rhythm; Erythrocyte Count; Female; Immunity, Innate; Leukocyte Count | 2008 |
Multiple melatonin target tissues mediate termination of photorefractoriness by long day lengths in Siberian hamsters.
Topics: Animals; Body Weight; Circadian Rhythm; Cricetinae; Drug Implants; Male; Melatonin; Phodopus; Photop | 2008 |
Melatonin pretreatment attenuates 2-bromopropane-induced testicular toxicity in rats.
Topics: Animals; Antioxidants; Body Weight; Epididymis; Glutathione; Glutathione Transferase; Hydrocarbons, | 2009 |
Photoperiodic regulation of satiety mediating neuropeptides in the brainstem of the seasonal Siberian hamster (Phodopus sungorus).
Topics: Animals; Area Postrema; Body Weight; Brain Stem; Cricetinae; Energy Metabolism; Feeding Behavior; Ge | 2009 |
NEU-P11, a novel melatonin agonist, inhibits weight gain and improves insulin sensitivity in high-fat/high-sucrose-fed rats.
Topics: Animals; Body Mass Index; Body Weight; Dietary Fats; Dietary Sucrose; Eating; Glucose; Insulin; Male | 2009 |
Protective role of melatonin against the mercury induced oxidative stress in the rat thyroid.
Topics: Animals; Antioxidants; Body Weight; Dose-Response Relationship, Drug; Enzymes; Male; Melatonin; Merc | 2010 |
Melatonin preserves longevity protein (sirtuin 1) expression in the hippocampus of total sleep-deprived rats.
Topics: Adrenocorticotropic Hormone; Animals; Body Weight; Central Nervous System Depressants; Corticosteron | 2009 |
Effect of melatonin implants on sexual activity in Mediterranean goat females without separation from males.
Topics: Animals; Body Composition; Body Weight; Breeding; Drug Implants; Estrus; Female; Goats; Luteinizing | 2009 |
Melatonin treatment potentiates neurodegeneration in a rat rotenone Parkinson's disease model.
Topics: Animals; Body Weight; Cell Count; Cell Death; Corpus Striatum; Disease Models, Animal; Dopamine; Mel | 2010 |
Possible involvement of GABAergic mechanism in protective effect of melatonin against sleep deprivation-induced behaviour modification and oxidative damage in mice.
Topics: Animals; Antioxidants; Anxiety; Behavior, Animal; Body Weight; Dose-Response Relationship, Drug; Fem | 2009 |
Melatonin improves presynaptic protein, SNAP-25, expression and dendritic spine density and enhances functional and electrophysiological recovery following transient focal cerebral ischemia in rats.
Topics: Animals; Blotting, Western; Body Weight; Dendritic Spines; Gene Expression Regulation; Ischemic Atta | 2009 |
Constant light induces alterations in melatonin levels, food intake, feed efficiency, visceral adiposity, and circadian rhythms in rats.
Topics: Adaptation, Psychological; Adiposity; Algorithms; Animals; Body Weight; Circadian Rhythm; Drinking; | 2009 |
Evaluation of management variables to advance conception and calving date of red deer (Cervus elaphus) in New Zealand venison production systems.
Topics: Agriculture; Animal Nutritional Physiological Phenomena; Animals; Body Weight; Breeding; Deer; Diet; | 2010 |
Functional and biochemical evidence indicating beneficial effect of Melatonin and Nicotinamide alone and in combination in experimental diabetic neuropathy.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Diabetic Neuropathies; Disease Models, Animal; Do | 2010 |
Melatonin modulates glucose homeostasis during winter dormancy in a vespertilionid bat, Scotophilus heathi.
Topics: Adipose Tissue; Animals; Blood Glucose; Body Weight; Chiroptera; Glucose; Glucose Tolerance Test; Gl | 2010 |
Synergistic effect of melatonin on exercise-induced neuronal reconstruction and functional recovery in a spinal cord injury animal model.
Topics: Analysis of Variance; Animals; Blotting, Western; Body Weight; Disease Models, Animal; Drug Synergis | 2010 |
Melatonin protection on mercury-exerted brain toxicity in the rat.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Brain; Cerebellum; Cerebrum; Drug Antagonism; Env | 2010 |
Possible mechanisms of weight loss of Siberian hamsters (Phodopus sungorus sungorus) exposed to short photoperiod.
Topics: Adipocytes; Adipose Tissue; Animals; Body Weight; Bucladesine; Catecholamines; Cricetinae; Light; Li | 2009 |
Adrenoceptor expression and diurnal rhythms of melatonin and its precursors in the pineal gland of type 2 diabetic goto-kakizaki rats.
Topics: Animals; Blood Glucose; Body Weight; Chromatography, High Pressure Liquid; Circadian Rhythm; Diabete | 2010 |
Protective effects of melatonin and Glycyrrhiza glabra extract on ochratoxin A--induced damages on testes in mature rats.
Topics: Animals; Antioxidants; Body Weight; Cell Differentiation; Glycyrrhiza; Male; Melatonin; Ochratoxins; | 2011 |
Seasonal regulation of reproduction: altered role of melatonin under naturalistic conditions in hamsters.
Topics: Animals; Body Weight; Cricetinae; Gonads; Male; Melatonin; Phodopus; Photoperiod; Pineal Gland; Repr | 2010 |
Melatonin treatment mimics the antidepressant action in chronic corticosterone-treated mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Body Weight; Bromodeoxyuridine; Cell Growth Proces | 2010 |
Effects of exogenous melatonin on in vivo embryo viability and oocyte competence of undernourished ewes after weaning during the seasonal anestrus.
Topics: Anestrus; Animals; Body Weight; Embryo, Mammalian; Embryonic Development; Female; Malnutrition; Mela | 2010 |
Melatonin effect on plasma adiponectin, leptin, insulin, glucose, triglycerides and cholesterol in normal and high fat-fed rats.
Topics: Adipokines; Analysis of Variance; Animals; Blood Glucose; Body Weight; Cholesterol; Dietary Fats; In | 2010 |
An intact dorsomedial hypothalamic nucleus, but not the subzona incerta or reuniens nucleus, is necessary for short-day melatonin signal-induced responses in Siberian hamsters.
Topics: Adipose Tissue, White; Animals; Body Weight; Cricetinae; Dorsomedial Hypothalamic Nucleus; Eating; F | 2011 |
Melatonin prevents hypertension and increased asymmetric dimethylarginine in young spontaneous hypertensive rats.
Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Blotting, Western; Body Weight; Citrulline; | 2010 |
Melatonin protects against transient focal cerebral ischemia in both reproductively active and estrogen-deficient female rats: the impact of circulating estrogen on its hormetic dose-response.
Topics: Animals; Animals, Newborn; Body Weight; Cell Line; Cells, Cultured; Estrogens; Female; Interleukin-6 | 2011 |
Absence of melatonin induces night-time hepatic insulin resistance and increased gluconeogenesis due to stimulation of nocturnal unfolded protein response.
Topics: Adiposity; Animals; Body Weight; Circadian Rhythm; Eating; Gluconeogenesis; Immunoblotting; Insulin | 2011 |
Case series of perimenopausal women with insomnia treated with mirtazapine followed by prolonged-release melatonin add-on and monotherapy.
Topics: Antidepressive Agents, Tricyclic; Body Weight; Delayed-Action Preparations; Dose-Response Relationsh | 2011 |
Melatonin improves mitochondrial respiratory chain activity and liver morphology in ob/ob mice.
Topics: Animals; Blotting, Western; Body Weight; Electron Transport Chain Complex Proteins; Fatty Liver; His | 2011 |
Ameliorative action of melatonin on oxidative damage induced by atrazine toxicity in rat erythrocytes.
Topics: Acetylcholinesterase; Adenosine Triphosphatases; Animals; Antioxidants; Atrazine; Body Weight; Catal | 2011 |
Long-term exogenous melatonin treatment modulates overall feed efficiency and protects ovarian tissue against injuries caused by ethanol-induced oxidative stress in adult UChB rats.
Topics: Alcohol Drinking; Animals; Antioxidants; Body Weight; Central Nervous System Depressants; Estrous Cy | 2011 |
Sustained melatonin treatment blocks body mass, pelage, reproductive, and fever responses to short day lengths in female Siberian hamsters.
Topics: Adaptation, Physiological; Animals; Antioxidants; Body Weight; Cricetinae; Female; Fever; Lipopolysa | 2011 |
Melatonin prevents oxidative stress in ovariectomized rats treated with aluminium.
Topics: Aldosterone; Aluminum; Aluminum Compounds; Animals; Antioxidants; Body Weight; Female; Guanosine Tri | 2011 |
Pentoxifylline and melatonin in combination with pioglitazone ameliorate experimental non-alcoholic fatty liver disease.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Biomarkers; Body Weight; C | 2011 |
Physical activity, sedentary behavior, and melatonin among rotating shift nurses.
Topics: Adult; Alcohol Drinking; Body Weight; Energy Metabolism; Female; Humans; Melatonin; Middle Aged; Mot | 2011 |
Plasticity changes in adult metabolic homeostasis and tissue oxidative stress: neonatal programming by corticosterone and melatonin as deprogrammer.
Topics: Animals; Animals, Newborn; Body Weight; Corticosterone; Drinking; Eating; Female; Growth and Develop | 2012 |
Beneficial effects of endogenous and exogenous melatonin on neural reconstruction and functional recovery in an animal model of spinal cord injury.
Topics: Analysis of Variance; Animals; Autophagy; Blotting, Western; Body Weight; Disease Models, Animal; Ma | 2012 |
The fat body of bullfrog (Lithobates catesbeianus) tadpoles during metamorphosis: changes in mass, histology, and melatonin content and effect of food deprivation.
Topics: Adipocytes; Animals; Body Weight; Fat Body; Food Deprivation; Larva; Melatonin; Metamorphosis, Biolo | 2011 |
Effects of electromagnetic radiation from 3G mobile phone on heart rate, blood pressure and ECG parameters in rats.
Topics: Analysis of Variance; Animals; Antioxidants; Blood Pressure; Body Weight; Cell Phone; Electrocardiog | 2012 |
Melatonin and succinate reduce rat liver mitochondrial dysfunction in diabetes.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Kidney; Liver; L | 2011 |
Melatonin delays clutch initiation in a wild songbird.
Topics: Animals; Body Weight; Clutch Size; Female; Germany; Melatonin; Motor Activity; Reproduction; Seasons | 2012 |
Melatonin improves metabolic syndrome induced by high fructose intake in rats.
Topics: Adipokines; Analysis of Variance; Animals; Antioxidants; Blood Glucose; Body Weight; Cholesterol; Di | 2012 |
The effect of melatonin on body mass and behaviour of rats during an exposure to microwave radiation from mobile phone.
Topics: Animals; Antioxidants; Behavior, Animal; Body Mass Index; Body Weight; Cell Phone; Male; Melatonin; | 2012 |
Photoperiod regulates corticosterone rhythms by altered adrenal sensitivity via melatonin-independent mechanisms in Fischer 344 rats and C57BL/6J mice.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Body Weight; Melatonin; Mice; Mice, Inbred C57 | 2012 |
Methylphenidate effects on blood serotonin and melatonin levels may help to synchronise biological rhythms in children with ADHD.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Body Height; Body Mass Index; Body Weight | 2013 |
Melatonin ameliorates oxidative damage in hyperglycemia-induced liver injury.
Topics: Animals; Antioxidants; Body Weight; Diabetes Mellitus, Experimental; DNA Damage; Enzyme-Linked Immun | 2012 |
Exposure to short days, but not short-term melatonin, enhances humoral immunity of male Syrian hamsters (Mesocricetus auratus).
Topics: Animals; Antibodies; Antibody Formation; Body Weight; Cricetinae; Hemocyanins; Light; Male; Melatoni | 2002 |
Alteration of internal circadian phase relationships after morning versus evening carbohydrate-rich meals in humans.
Topics: Adult; Body Temperature; Body Weight; Circadian Rhythm; Dietary Carbohydrates; Energy Metabolism; He | 2002 |
Determinants of the annual pattern of reproduction in mature male Merino and Suffolk sheep: modification of responses to photoperiod by an annual cycle in food supply.
Topics: Animals; Body Weight; Diet; Follicle Stimulating Hormone; Food Supply; Luteinizing Hormone; Male; Me | 2002 |
Melatonin reduces renal interstitial inflammation and improves hypertension in spontaneously hypertensive rats.
Topics: Administration, Oral; Animals; Antioxidants; Blood Pressure; Body Weight; Disease Models, Animal; Dr | 2003 |
Reversal of biochemical and behavioral parameters of brain aging by melatonin and acetyl L-carnitine.
Topics: Acetylcarnitine; Aging; Animals; Body Weight; Cerebral Cortex; Down-Regulation; Encephalitis; Explor | 2002 |
Hormonal changes during 17 days of head-down bed-rest.
Topics: Adult; Bed Rest; Body Weight; Catecholamines; Circadian Rhythm; Diuresis; Growth Hormone; Head-Down | 2003 |
The induction of low nocturnal secretion of melatonin caused by reverse feeding rhythms depends on availability of macronutrient diets.
Topics: Animals; Arylamine N-Acetyltransferase; Body Weight; Circadian Rhythm; Diet; Dietary Carbohydrates; | 2002 |
S22153, a melatonin antagonist, dissociates different aspects of photoperiodic responses in Syrian hamsters.
Topics: Adipose Tissue, Brown; Animals; Body Temperature Regulation; Body Weight; Cricetinae; Hibernation; M | 2003 |
Termination of neuroendocrine refractoriness to melatonin in Siberian hamsters (Phodopus sungorus).
Topics: Animals; Body Weight; Cricetinae; Female; Male; Melatonin; Neurosecretory Systems; Phodopus; Photope | 2003 |
Suppression of hypothalamic pro-opiomelanocortin (POMC) gene expression by daily melatonin supplementation in aging rats.
Topics: Aging; Animals; Body Weight; Gene Expression Regulation; In Situ Hybridization; Male; Melatonin; Pro | 2003 |
Melatonin increases oestradiol-induced bone formation in ovariectomized rats.
Topics: Animals; Body Weight; Bone Development; Estradiol; Female; Melatonin; Ovariectomy; Rats; Rats, Wista | 2003 |
Dose-dependent effect of melatonin on life span and spontaneous tumor incidence in female SHR mice.
Topics: Animals; Body Weight; Chromosome Aberrations; Dose-Response Relationship, Drug; Eating; Estrus; Fema | 2003 |
Effects of melatonin on oxidative-antioxidative status of tissues in streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Female; Free Rad | 2003 |
Melatonin-induced reduction in age-related accumulation of oxidative damage in mice.
Topics: Aging; Animals; Body Weight; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Lipid Pero | 2003 |
Temporal integration of melatonin infusion duration: signal averaging versus frequency dependence.
Topics: Animals; Body Weight; Circadian Rhythm; Cricetinae; Dose-Response Relationship, Drug; Infusion Pumps | 2003 |
Melatonin effects on metabolism independent of gonad function.
Topics: Adipose Tissue; Age Factors; Animals; Body Composition; Body Weight; Castration; Circadian Rhythm; E | 2003 |
Protective effects of chronic melatonin treatment against renal injury in streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Immunohistochemi | 2003 |
Effect of melatonin suppression on scoliosis development in chickens by either constant light or surgical pinealectomy.
Topics: Animals; Body Weight; Chickens; Light; Melatonin; Pineal Gland; Postoperative Complications; Scolios | 2003 |
Protective effect of melatonin against fractionated irradiation-induced epiphyseal injury in a weanling rat model.
Topics: Animals; Body Weight; Dose Fractionation, Radiation; Epiphyses; Free Radical Scavengers; Melatonin; | 2003 |
Independence of circadian entrainment state and responses to melatonin in male Siberian hamsters.
Topics: Animals; Body Weight; Circadian Rhythm; Cricetinae; Drug Implants; Male; Melatonin; Periodicity; Pho | 2003 |
Melatonin implants disrupt developmental synchrony regulated by flexible interval timers.
Topics: Animals; Biological Clocks; Body Weight; Cricetinae; Drug Implants; Estrus Synchronization; Female; | 2003 |
Delayed treatment with melatonin enhances electrophysiological recovery following transient focal cerebral ischemia in rats.
Topics: Animals; Behavior, Animal; Body Weight; Cerebral Cortex; Cerebrovascular Circulation; Corpus Striatu | 2004 |
Effects of melatonin on skeletal muscle of rats with experimental hyperthyroidism.
Topics: Adipose Tissue; Animals; Blood Vessels; Body Weight; Glycogen; Hyperthyroidism; Male; Mast Cells; Me | 2003 |
Both zinc deficiency and supplementation affect plasma melatonin levels in rats.
Topics: Animal Feed; Animals; Body Weight; Male; Melatonin; Rats; Rats, Sprague-Dawley; Zinc | 2003 |
Melatonin supplementation can ameliorate the detrimental effects of heat stress on performance and carcass traits of Japanese quail.
Topics: Animals; Body Weight; Coturnix; Diet; Dietary Supplements; Heat Stress Disorders; Hot Temperature; M | 2003 |
Effect of zinc and melatonin supplementation on cellular immunity in rats with toxoplasmosis.
Topics: Animals; Body Weight; Dietary Supplements; Immunity, Cellular; Male; Melatonin; Rats; Rats, Sprague- | 2003 |
Continuous melatonin treatment and fasting in the raccoon dog (Nyctereutes procyonoides)--vernal body weight regulation and reproduction.
Topics: Adipose Tissue; Animals; Body Mass Index; Body Weight; Carnivora; Eating; Fasting; Ghrelin; Growth H | 2004 |
Attenuation of diurnal rhythms in plasma levels of melatonin and cortisol, and hypothalamic contents of vasotocin and isotocin mRNAs in pre-spawning chum salmon.
Topics: Animals; Body Weight; Circadian Rhythm; Female; Hydrocortisone; Hydroxyprogesterones; Hypothalamus; | 2004 |
Ascorbic acid and melatonin reduce heat-induced performance inhibition and oxidative stress in Japanese quails.
Topics: Animals; Antioxidants; Ascorbic Acid; Blood Glucose; Body Weight; Cholesterol; Coturnix; Eating; Fec | 2004 |
Effect of melatonin and stobadine on maternal and embryofoetal toxicity in rats due to intrauterine hypoxia induced by phenytoin administration.
Topics: Abnormalities, Drug-Induced; Analysis of Variance; Animals; Animals, Newborn; Anticonvulsants; Body | 2004 |
Light/dark cycle-dependent metabolic changes in adipose tissue of pinealectomized rats.
Topics: Adipocytes; Adipose Tissue; Analysis of Variance; Animals; Blood Glucose; Body Weight; Circadian Rhy | 2004 |
Orally administered tryptophan and experimental type 2 diabetes.
Topics: Administration, Oral; Animals; Antioxidants; Blood Glucose; Body Weight; Catalase; Diabetes Mellitus | 2004 |
Melatonin treatment protects against diabetes-induced functional and biochemical changes in rat aorta and corpus cavernosum.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental | 2004 |
Melatonin blocks inhibitory effects of prolactin on photoperiodic induction of gain in body mass, testicular growth and feather regeneration in the migratory male redheaded bunting (Emberiza bruniceps).
Topics: Animals; Body Weight; Feathers; Finches; Male; Melatonin; Photoperiod; Prolactin; Regeneration; Test | 2004 |
Circannual leptin and ghrelin levels of the blue fox (Alopex lagopus) in reference to seasonal rhythms of body mass, adiposity, and food intake.
Topics: Analysis of Variance; Animals; Body Composition; Body Weight; Eating; Finland; Food Deprivation; Fox | 2005 |
Temporal oscillations of thyroid hormones in long term melatonin treated rats.
Topics: Animals; Antioxidants; Body Weight; Circadian Rhythm; Dose-Response Relationship, Drug; Immunoradiom | 2005 |
Seasonal variations in circadian rhythms coincide with a phase of sensitivity to short photoperiods in the European hamster.
Topics: Animals; Body Weight; Circadian Rhythm; Creatinine; Cricetinae; Female; Gonads; Male; Melatonin; Mot | 2005 |
Role of adiposity hormones in the mouse during fasting and winter-acclimatization.
Topics: Acclimatization; Animals; Body Weight; Circadian Rhythm; Fasting; Ghrelin; Growth Hormone; Leptin; M | 2005 |
Effects of zinc deficiency and pinealectomy on cellular immunity in rats infected with Toxoplasma gondii.
Topics: Animals; Body Weight; Immunity, Cellular; Lymphocyte Count; Melatonin; Pineal Gland; Rats; Rats, Spr | 2005 |
Exposure to light-at-night increases the growth of DMBA-induced mammary adenocarcinomas in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Body Weight; Circadian Rhythm; Darkness; | 2006 |
Melatonin increases tissue accumulation and toxicity of cadmium in the bank vole (Clethrionomys glareolus).
Topics: Animals; Arvicolinae; Body Weight; Cadmium; Kidney; Lipid Peroxidation; Liver; Melatonin; Organ Size | 2005 |
Modulation by melatonin of the cardiotoxic and antitumor activities of adriamycin.
Topics: Animals; Antibiotics, Antineoplastic; Body Weight; Breast Neoplasms; Cell Line, Tumor; Comet Assay; | 2005 |
Melatonin as protective agent for the cytotoxic effects of diazinon in the spermatogenesis in the earthworm Eisenia foetida.
Topics: Animals; Biological Assay; Body Weight; Cholinesterase Inhibitors; Cytoprotection; Diazinon; Environ | 2005 |
Circadian and extracircadian exploration during daytime hours of circulating corticosterone and other endocrine chronomes.
Topics: Animals; Body Temperature; Body Weight; Chronobiology Phenomena; Circadian Rhythm; Corticosterone; E | 2005 |
Melatonin enhances NADPH-diaphorase activities in the hypothalamus of maternally-separated rats.
Topics: Animals; Animals, Newborn; Body Weight; Cell Count; Female; Histocytochemistry; Hypothalamus; Male; | 2006 |
Depression of glucose levels and partial restoration of pancreatic beta-cell damage by melatonin in streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Free Radical Scavengers; Image | 2006 |
Modulation of biochemical circadian rhythms during long-term melatonin treatment in rats.
Topics: Animals; Blood Glucose; Blood Proteins; Body Weight; Circadian Rhythm; Dose-Response Relationship, D | 2006 |
Effects of melatonin administration on intestinal adaptive response after massive bowel resection in rats.
Topics: Adaptation, Physiological; Animals; Antioxidants; Body Weight; Ileum; Intestinal Mucosa; Intestine, | 2006 |
Effects of melatonin on streptozotocin-induced diabetic liver injury in rats.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Hyperglycemia; L | 2006 |
Melatonin prevents X-ray irradiation induced oxidative damagein peripheral blood and spleen of the seasonally breeding rodent, Funambulus pennanti during reproductively active phase.
Topics: Animals; Apoptosis; Biomarkers; Body Weight; Leukocyte Count; Lipid Peroxidation; Lymphocyte Activat | 2006 |
Influences of sex and saline intake on diurnal changes in plasma melatonin and osmoregulatory hormones of Pekin ducks (Anas platyrhynchos).
Topics: Aldosterone; Angiotensin II; Animals; Body Weight; Circadian Rhythm; Ducks; Female; Male; Melatonin; | 2006 |
Preclinical evaluation of pharmacokinetics and safety of melatonin in propylene glycol for intravenous administration.
Topics: Animals; Blood Cell Count; Blood Pressure; Body Temperature; Body Weight; Brain; Drug Evaluation, Pr | 2006 |
Effects of pinealectomy and exogenous melatonin on immunohistochemical ghrelin staining of arcuate nucleus and serum ghrelin leves in the rat.
Topics: Analysis of Variance; Animals; Arcuate Nucleus of Hypothalamus; Body Weight; Eating; Ghrelin; Immuno | 2006 |
Role of the hypothalamic suprachiasmatic nucleus in the effect of melatonin on the thymus, adrenal glands, and spleen in rats.
Topics: Adrenal Glands; Animals; Body Weight; Electrophysiology; Hypothalamus; Male; Melatonin; Organ Size; | 2006 |
Longitudinal study of the simultaneous secretion of melatonin and leptin during normal puberty.
Topics: Adipose Tissue; Adolescent; Adolescent Development; Body Weight; Child; Female; Gonadotropin-Releasi | 2007 |
Intake of melatonin is associated with amelioration of physiological changes, both metabolic and morphological pathologies associated with obesity: an animal model.
Topics: Animals; Arteries; Blood Pressure; Body Weight; Cholesterol; Dietary Fats; Electric Stimulation; Ele | 2007 |
Effect of melatonin on salt gland and kidney function of gulls, Larus glaucescens.
Topics: Aldosterone; Angiotensin II; Animals; Body Weight; Charadriiformes; Infusion Pumps; Kidney; Melatoni | 2007 |
Melatonin levels during the first week of life and their relation with the antioxidant response in the perinatal period.
Topics: Antioxidants; Body Weight; Free Radical Scavengers; Gestational Age; Humans; Infant, Low Birth Weigh | 2007 |
Effects of melatonin on the endometrial morphology and embryo implantation in rats.
Topics: Animals; Body Weight; Embryo Implantation; Endometrium; Estradiol; Female; Male; Melatonin; Organ Si | 2008 |
Multiple protective effects of melatonin against maternal cholestasis-induced oxidative stress and apoptosis in the rat fetal liver-placenta-maternal liver trio.
Topics: Animals; Apoptosis; Body Weight; Cholestasis; Female; Glutathione; Lipid Peroxidation; Liver; Melato | 2007 |
Melatonin and estradiol effects on food intake, body weight, and leptin in ovariectomized rats.
Topics: Analysis of Variance; Animals; Body Weight; Cholesterol; Disease Models, Animal; Eating; Estradiol C | 2007 |
Beneficial properties of melatonin in an experimental model of pancreatic cancer.
Topics: Animals; Antioxidants; Body Weight; Cricetinae; Disease Models, Animal; Lipid Peroxides; Male; Melat | 2007 |
The role of melatonin in the pathogenesis of hypertension in rats with metabolic syndrome.
Topics: Animals; Blood Pressure; Body Weight; Dietary Sucrose; Dietary Supplements; Disease Models, Animal; | 2008 |
Pinealectomy and melatonin administration in rats: their effects on plasma leptin levels and relationship with zinc.
Topics: Analysis of Variance; Animals; Body Weight; Leptin; Male; Melatonin; Pineal Gland; Radioimmunoassay; | 2007 |
Effects of mobile phone electromagnetic fields at nonthermal SAR values on melatonin and body weight of Djungarian hamsters (Phodopus sungorus).
Topics: Animals; Body Weight; Cell Phone; Cricetinae; Electromagnetic Fields; Male; Melatonin; Organ Size; P | 2008 |
Prolonged melatonin administration in 6-month-old Sprague-Dawley rats: metabolic alterations.
Topics: Animals; Body Weight; Cholesterol; Circadian Rhythm; Corticosterone; Female; Glycemic Index; Glycoge | 2008 |
[Alimentary and oxygen deprivation as the modulator of the bone tissue physiological remodelling rate in young rats].
Topics: Alkaline Phosphatase; Animals; Body Weight; Bone and Bones; Bone Remodeling; Caloric Restriction; El | 2008 |
Effect of a high-fat diet on 24-h pattern of circulating levels of prolactin, luteinizing hormone, testosterone, corticosterone, thyroid-stimulating hormone and glucose, and pineal melatonin content, in rats.
Topics: Animals; Blood Glucose; Body Weight; Circadian Rhythm; Corticosterone; Diet; Dietary Fats; Hormones; | 2008 |
Effect of melatonin on thyroid hormone secretion rate and feed consumption of female rats.
Topics: Adrenal Glands; Aging; Animals; Appetite; Appetite Regulation; Body Weight; Eating; Female; Melatoni | 1967 |
Effect of chronic lithium treatment on rat pineal rhythms: N-acetyltransferase, N-acetylserotonin and melatonin.
Topics: 5-Hydroxytryptophan; Acetyltransferases; Animals; Body Weight; Circadian Rhythm; Cyclic AMP; Hydroxy | 1983 |
Photoperiodic regulation of body mass, food intake, and reproduction in meadow voles.
Topics: Adipose Tissue, Brown; Animals; Arvicolinae; Body Water; Body Weight; Circadian Rhythm; Darkness; En | 1983 |
Differential responsiveness of the reproductive system of blind or melatonin-treated male hamsters to injections of gonadotrophin-releasing hormone (GnRH) and/or prolactin.
Topics: Animals; Blindness; Body Weight; Cricetinae; Drug Interactions; Genitalia, Male; Gonadotropin-Releas | 1984 |
Seasonal obesity in Syrian hamsters: effects of age, diet, photoperiod, and melatonin.
Topics: Age Factors; Animals; Body Weight; Cricetinae; Diet; Dietary Fats; Female; Melatonin; Mesocricetus; | 1984 |
Role of the hypothalamic paraventricular nucleus in neuroendocrine responses to daylength in the golden hamster.
Topics: Animals; Body Weight; Circadian Rhythm; Cricetinae; Darkness; Light; Male; Melatonin; Mesocricetus; | 1984 |
Pineal gland size and serum melatonin levels in male rats are not correlated.
Topics: Animals; Body Weight; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains | 1984 |
Melatonin in relation to body measures, sex, age, season and the use of drugs in patients with major affective disorders and healthy subjects.
Topics: Adult; Age Factors; Bipolar Disorder; Body Height; Body Weight; Contraceptives, Oral; Depressive Dis | 1984 |
Lithium and melatonin in pigmented eye rats: effects of dose and time of day.
Topics: Animals; Body Weight; Drinking Behavior; Erythrocytes; Lithium; Male; Melatonin; Pineal Gland; Rats | 1984 |
Melatonin protects rats from injurious effects of a glucocorticoid, dexamethasone.
Topics: Adrenal Glands; Animals; Atrophy; Body Weight; Dexamethasone; Female; Melatonin; Rats; Thymus Gland | 1984 |
Growth and food intake of intact and pinealectomised chickens treated with melatonin and triiodothyronine.
Topics: Animals; Body Weight; Chickens; Darkness; Eating; Electroencephalography; Male; Melatonin; Pineal Gl | 1983 |
Photoperiodic control of body weight and energy metabolism in Syrian hamsters (Mesocricetus auratus): role of pineal gland, melatonin, gonads, and diet.
Topics: Adipose Tissue, Brown; Animals; Body Weight; Castration; Circadian Rhythm; Cricetinae; Diet; Dietary | 1984 |
Effects of melatonin implants in ewe lambs.
Topics: Animals; Body Weight; Drug Implants; Female; Melatonin; Pineal Gland; Progesterone; Prolactin; Seaso | 1984 |
Effects of photoperiod and gonadectomy on food intake, body weight, and body composition in Siberian hamsters.
Topics: Adipose Tissue, Brown; Animals; Body Composition; Body Weight; Castration; Cricetinae; Eating; Femal | 1984 |
Induction of winter fur growth in mink (Mustela vison) with melatonin.
Topics: Animals; Body Weight; Drug Implants; Female; Hair; Lighting; Male; Melatonin; Mink; Seasons | 1984 |
Reduced nocturnal melatonin secretion in chronic schizophrenia: relationship to body weight.
Topics: Adult; Aged; Body Weight; Chronic Disease; Circadian Rhythm; Humans; Male; Melatonin; Middle Aged; S | 1982 |
24-hour profiles of melatonin, cortisol, insulin, C-peptide and GIP following a meal and subsequent fasting.
Topics: Adult; Body Weight; C-Peptide; Fasting; Female; Gastric Inhibitory Polypeptide; Humans; Hydrocortiso | 1982 |
Variation of urinary melatonin excretion in humans during the first 30 years of life.
Topics: Adolescent; Adult; Age Factors; Body Weight; Child; Child, Preschool; Creatinine; Humans; Infant; In | 1981 |
Melatonin and lighting condition: absence of long-term effects on food intake and body weight regulation in the albino rats.
Topics: Animals; Body Weight; Drug Implants; Eating; Lighting; Male; Melatonin; Periodicity; Rats | 1980 |
Apparent dualistic effects of twice daily melatonin administration on reproductive organs in male golden hamsters.
Topics: Animals; Body Weight; Cricetinae; Dose-Response Relationship, Drug; Genitalia, Male; Light; Male; Me | 1981 |
Effects of pinealectomy and melatonin treatment on growth in the goldfish, Carassius auratus.
Topics: Animals; Biometry; Body Weight; Cyprinidae; Goldfish; Melatonin; Periodicity; Pineal Gland | 1980 |
Influence of exogenously administered melatonin on the reproductive system and prolactin levels in underfed male rats.
Topics: Animals; Body Weight; Genitalia, Male; Male; Melatonin; Nutrition Disorders; Organ Size; Pituitary G | 1980 |
An interaction between the pineal gland and olfactory deprivation in potentiating the effects of melatonin on gonads, accessory sex organs, and prolactin in male rats.
Topics: Animals; Body Weight; Genitalia, Male; Gonadotropins; Male; Melatonin; Olfactory Bulb; Organ Size; P | 1980 |
Surgical removal of the olfactory bulbs increases sensitivity of the reproductive system of female rats to the inhibitory effects of late afternoon melatonin injections.
Topics: Animals; Blindness; Body Weight; Darkness; Drug Administration Schedule; Female; Gonadotropins, Pitu | 1980 |
Rat self administration of ethanol: enhancement by darkness and exogenous melatonin.
Topics: Animals; Body Weight; Circadian Rhythm; Darkness; Ethanol; Light; Melatonin; Rats; Self Administrati | 1980 |
Gonadal responses of the male tau mutant Syrian hamster to short-day-like programmed infusions of melatonin.
Topics: Animals; Body Weight; Circadian Rhythm; Cricetinae; Luteinizing Hormone; Male; Melatonin; Mesocricet | 1995 |
Manipulating melatonin in red deer (Cervus elaphus): differences in the response to food restriction and lactation on the timing of the breeding season and prolactin-dependent pelage changes.
Topics: Animal Feed; Animals; Body Weight; Deer; Drug Implants; Feeding Behavior; Female; Fertility; Food Su | 1995 |
Effects of long-term administration of melatonin and a putative antagonist on the ageing rat.
Topics: 5-Methoxytryptamine; Aging; Animals; Body Weight; Hypothalamus; Iodine Radioisotopes; Male; Medulla | 1995 |
Effect of season on LH secretion in ovariectomized Australian cashmere does.
Topics: Animals; Body Weight; Estrogens; Female; Goats; Immunization; Luteinizing Hormone; Melatonin; Ovarie | 1995 |
Classification of patients with affective disorders using platelet monoamine oxidase activity, serum melatonin and post-dexamethasone cortisol.
Topics: Adult; Age Factors; Blood Platelets; Body Height; Body Weight; Dexamethasone; Female; Humans; Hydroc | 1995 |
Influence of photoperiod on pineal melatonin synthesis, fur color, body weight, and reproductive function in the female Djungarian hamster, Phodopus sungorus.
Topics: Animals; Body Weight; Circadian Rhythm; Cricetinae; Female; Hair Color; Hydroxyindoleacetic Acid; Me | 1993 |
Response of collared lemmings to melatonin: I. Implants and photoperiod.
Topics: Animals; Arvicolinae; Body Weight; Capsules; Drug Implants; Female; Hair; Hoof and Claw; Melatonin; | 1994 |
Response of collared lemmings to melatonin: II. Infusions and photoperiod.
Topics: Animals; Arvicolinae; Body Weight; Female; Hair; Hoof and Claw; Infusions, Parenteral; Melatonin; Or | 1994 |
Preliminary evidence of a synergistic alpha 1- and beta 1-adrenoceptor regulation of rat pineal hydroxyindole-O-methyltransferase.
Topics: Acetylserotonin O-Methyltransferase; Aging; Animals; Body Weight; Circadian Rhythm; Doxazosin; Fencl | 1995 |
Gonadal growth and hormone concentrations in photoregressed Siberian hamsters: pinealectomy versus photostimulation.
Topics: Animals; Body Weight; Cricetinae; Follicle Stimulating Hormone; Light; Male; Melatonin; Organ Size; | 1994 |
Photoperiod and melatonin affect testicular growth in the marsh rice rat (Oryzomys palustris).
Topics: Animals; Body Weight; Male; Melatonin; Organ Size; Photoperiod; Pineal Gland; Rats; Sigmodontinae; T | 1994 |
Effects of photoperiod, pinealectomy, and melatonin implants on testicular development in juvenile Siberian hamsters (Phodopus sungorus).
Topics: Animals; Body Weight; Cricetinae; Male; Melatonin; Phodopus; Photoperiod; Pineal Gland; Sexual Matur | 1994 |
Effect of neonatal melatonin and 5-methoxytriptamine administration on the female Indian palm squirrel (Funambulus pennanti).
Topics: 5-Methoxytryptamine; Animals; Animals, Newborn; Body Weight; Estradiol; Female; Hair; Injections, Su | 1994 |
Cortisol decreases 2[125I]iodomelatonin binding sites in the duck thymus.
Topics: Adrenal Cortex Hormones; Animals; Binding Sites; Body Weight; Ducks; Hydrocortisone; Injections, Int | 1994 |
Effect of pinealectomy and plane of nutrition on wool growth in Merino sheep.
Topics: Animal Nutritional Physiological Phenomena; Animals; Body Weight; Dietary Proteins; Male; Melatonin; | 1993 |
Hyperprolactinemia does not promote testicular recrudescence in photoregressed Siberian hamsters.
Topics: Animals; Body Weight; Cricetinae; Light; Male; Melatonin; Phodopus; Pineal Gland; Prolactin; Seasons | 1993 |
Sustained hormonal responses of Siberian hamsters (Phodopus sungorus) to a single longer day at weaning.
Topics: Animals; Body Weight; Cricetinae; Follicle Stimulating Hormone; Kinetics; Light; Male; Melatonin; Or | 1993 |
Effects of melatonin, testosterone and the two hormones administered in parallel on ventral prostate of the rat treated with stilbestrol in the first day of life.
Topics: Animals; Animals, Newborn; Atrophy; Body Weight; Diethylstilbestrol; Estrogens, Non-Steroidal; Lutei | 1995 |
Pharmacokinetics of melatonin in human sexual maturation.
Topics: Adolescent; Adult; Aging; Body Weight; Child; Circadian Rhythm; Female; Humans; Male; Melatonin; Pil | 1996 |
The zinc pool is involved in the immune-reconstituting effect of melatonin in pinealectomized mice.
Topics: Analysis of Variance; Animals; Body Weight; Male; Melatonin; Mice; Mice, Inbred BALB C; Pineal Gland | 1996 |
The effects of anterior hypothalamic lesions on short-day responses in Siberian hamsters given timed melatonin infusions.
Topics: Adipose Tissue; Animals; Body Weight; Cricetinae; Eating; Hypothalamus, Anterior; Injections, Subcut | 1996 |
Daily melatonin injections induce cytological changes in pars tuberalis-specific cells similar to short photoperiod.
Topics: Animals; Body Weight; Cricetinae; Female; Glycoproteins; Immunohistochemistry; Melatonin; Microscopy | 1995 |
Circadian adjustment of men and women to night work.
Topics: Adaptation, Physiological; Adult; Age Distribution; Analysis of Variance; Body Temperature; Body Wei | 1996 |
Reciprocal effects of chronic diazepam and melatonin on brain melatonin and benzodiazepine binding sites.
Topics: Animals; Body Weight; Brain; Cerebral Cortex; Diazepam; Flumazenil; Flunitrazepam; Kinetics; Male; M | 1996 |
Effects of both a melatonin agonist and antagonist on seasonal changes in body mass and energy intake in the garden dormouse.
Topics: Animals; Body Weight; Circadian Rhythm; Energy Intake; Energy Metabolism; Male; Melatonin; Motor Act | 1996 |
Melatonin administration following hemorrhagic shock decreases mortality from subsequent septic challenge.
Topics: Animals; Body Weight; Cecum; Hemorrhage; Ligation; Male; Melatonin; Mice; Mice, Inbred C3H; Sepsis; | 1996 |
Combination of melatonin and tamoxifen as a chemoprophylaxis against N-nitroso-N-methylurea-induced rat mammary tumors.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Carcinogens; Female; Mammary Glands, Animal; Mammary | 1997 |
Pattern of change in melatonin duration determines testicular responses in Siberian hamsters, Phodopus sungorus.
Topics: Animals; Body Weight; Cricetinae; Infusions, Intravenous; Male; Melatonin; Organ Size; Phodopus; Pho | 1997 |
Photoperiodic history and hypothalamic control of prolactin secretion before birth.
Topics: Animals; Animals, Newborn; Body Weight; Female; Fetus; Gestational Age; Hypothalamo-Hypophyseal Syst | 1997 |
Phase-advanced daily rhythms of melatonin, body temperature, and locomotor activity in food-restricted rats fed during daytime.
Topics: Animals; Body Temperature; Body Weight; Circadian Rhythm; Corticosterone; Food Deprivation; Iodine R | 1997 |
Phenotypic variation in seasonal adjustments of testis size, body weight, and food intake in deer mice: role of pineal function and ambient temperature.
Topics: Animals; Behavior, Animal; Body Weight; Circadian Rhythm; Eating; Energy Metabolism; Epididymis; Gon | 1997 |
Melatonin and colon carcinogenesis: I. Inhibitory effect of melatonin on development of intestinal tumors induced by 1,2-dimethylhydrazine in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Anticarcinogenic Agents; Body Weight; Colonic Neopla | 1997 |
Biological effects of continuous exposure of embryos and young chickens to electromagnetic fields emitted by video display units.
Topics: Animals; Antibody Formation; Body Weight; Chick Embryo; Chickens; Computer Terminals; Corticosterone | 1997 |
A mathematical model of production, distribution, and metabolism of melatonin in mammalian systems.
Topics: Animals; Arylamine N-Acetyltransferase; Blood Flow Velocity; Body Weight; Cardiac Output; Circadian | 1997 |
Lack of promoting effects of the electromagnetic near-field used for cellular phones (929.2 MHz) on rat liver carcinogenesis in a medium-term liver bioassay.
Topics: Adrenocorticotropic Hormone; Animals; Body Weight; Corticosterone; Diethylnitrosamine; Electromagnet | 1998 |
Dorsocaudal SCN microknife-cuts do not block short day responses in Siberian hamsters given melatonin infusions.
Topics: Adaptation, Physiological; Analysis of Variance; Animals; Body Weight; Cerebral Ventricles; Cricetin | 1998 |
Seasonal variation in live weight, testes size, testosterone, LH secretion, melatonin and thyroxine in Merino and Corriedale rams in a subtropical climate.
Topics: Animals; Body Weight; Climate; Hormones; Luteinizing Hormone; Male; Melatonin; Organ Size; Seasons; | 1998 |
Exogenous melatonin enhances cell-mediated, but not humoral, immune function in adult male deer mice (Peromyscus maniculatus).
Topics: Analysis of Variance; Animals; Antibody Formation; B-Lymphocytes; Body Weight; Climate; Drug Implant | 1998 |
Presence of links between zinc and melatonin during the circadian cycle in old mice: effects on thymic endocrine activity and on the survival.
Topics: Aging; Animals; Antioxidants; Body Weight; Cells, Cultured; Circadian Rhythm; Corticosterone; Male; | 1998 |
Possible involvement of neuropeptide Y in the seasonal control of hydroxyindole-O-methyltransferase activity in the pineal gland of the european hamster (Cricetus cricetus).
Topics: Acetylserotonin O-Methyltransferase; Analysis of Variance; Animals; Body Weight; Circadian Rhythm; C | 1998 |
Time-dependent effects of melatonin on immune measurements in male Syrian hamsters.
Topics: Animals; Body Weight; Cricetinae; Cytokines; Immune System; Immunoenzyme Techniques; Immunoglobulin | 1998 |
Melatonin administration increases the affinity of D2 dopamine receptors in the rat striatum.
Topics: Animals; Benzamides; Body Weight; Dopamine Antagonists; In Vitro Techniques; Male; Melatonin; Membra | 1998 |
Melatonin chimeras alter reproductive development and photorefractoriness in Siberian hamsters.
Topics: Adrenergic beta-Antagonists; Animals; Body Weight; Chimera; Cricetinae; Female; Follicle Stimulating | 1998 |
Pineal-independent regulation of photo-nonresponsiveness in the Siberian hamster (Phodopus sungorus).
Topics: Animals; Body Weight; Circadian Rhythm; Cricetinae; Light; Male; Melatonin; Motor Activity; Phodopus | 1999 |
Effect of melatonin and lighting schedule on energy metabolism in broiler chickens.
Topics: Animal Husbandry; Animals; Body Weight; Chickens; Circadian Rhythm; Diet; Energy Metabolism; Female; | 1999 |
Normative melatonin excretion: a multinational study.
Topics: Adolescent; Adult; Aging; Body Height; Body Weight; Climate; Female; Humans; Logistic Models; Male; | 1999 |
Frequency coding of melatonin signals sufficient to induce testicular growth in photoregressed Siberian hamsters.
Topics: Animals; Body Weight; Cricetinae; Follicle Stimulating Hormone; Male; Melatonin; Organ Size; Phodopu | 1999 |
Effects of 60 Hz magnetic field exposure on the pineal and hypothalamic-pituitary-gonadal axis in the Siberian hamster (Phodopus sungorus).
Topics: Adrenergic alpha-Agonists; Analysis of Variance; Animals; Body Weight; Cricetinae; Darkness; Environ | 1999 |
Melatonin and taurine reduce early glomerulopathy in diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diures | 1999 |
Zinc accumulation in adriamycin-induced cardiomyopathy in rats: effects of melatonin, a cardioprotective antioxidant.
Topics: Animals; Antioxidants; Ascites; Body Weight; Cardiomyopathies; Doxorubicin; Heart Ventricles; Lipid | 1999 |
A preliminary study on the effects of dietary energy and melatonin on the ex vivo production of progesterone and prostaglandin F2alpha by the corpora lutea and endometrial tissue of ewes.
Topics: Animal Nutritional Physiological Phenomena; Animals; Body Weight; Corpus Luteum; Dinoprost; Endometr | 1999 |
Resveratrol, melatonin, vitamin E, and PBN protect against renal oxidative DNA damage induced by the kidney carcinogen KBrO3.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Body Weight; Bromates; Carcinogens; Cyclic N-Oxides; | 1999 |
The tumor promoting effect of constant light exposure on diethylnitrosamine-induced hepatocarcinogenesis in rats.
Topics: Animals; Body Temperature; Body Weight; Carcinogens; Circadian Rhythm; Diethylnitrosamine; Laparotom | 1999 |
A therapeutic role for melatonin antagonism in experimental models of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Biological Availability; Body Weight; Circadi | 1999 |
Zinc coadministration attenuates melatonin's effect on nitric oxide production in mice.
Topics: Adipose Tissue; Animals; Blood Glucose; Body Weight; Fatty Acids, Nonesterified; Male; Melatonin; Mi | 1999 |
Maternal and developmental toxicity evaluation of melatonin administered orally to pregnant Sprague-Dawley rats.
Topics: Animals; Antioxidants; Aversive Therapy; Body Weight; Drinking; Eating; Female; Fetus; Male; Materna | 1999 |
Ventromedial hypothalamic mediation of photoperiodic gonadal responses in male Syrian hamsters.
Topics: Animals; Body Weight; Brain Mapping; Cricetinae; Follicle Stimulating Hormone; Gonads; Male; Melaton | 1999 |
Maternal photoperiodic exposures alter the neonatal growth, pineal functions and sexual development of the Indian palm squirrel F. pennanti. Short communication.
Topics: Animals; Body Weight; Estradiol; Female; Gonads; Light; Male; Melatonin; Organ Size; Periodicity; Ph | 1999 |
Food restriction alters the diurnal distribution of sleep in rats.
Topics: Animals; Body Temperature; Body Weight; Brain; Circadian Rhythm; Drinking; Eating; Food Deprivation; | 1999 |
In vitro melatonin treatment enhances splenocyte proliferation in prairie voles.
Topics: Animals; Arvicolinae; Body Weight; Cell Division; Concanavalin A; Female; Immunity, Cellular; Lympho | 2000 |
Daily melatonin administration to middle-aged male rats suppresses body weight, intraabdominal adiposity, and plasma leptin and insulin independent of food intake and total body fat.
Topics: Abdomen; Absorptiometry, Photon; Adipose Tissue; Administration, Oral; Adrenal Glands; Animals; Avoi | 2000 |
Influence of melatonin on immunotoxicity of cadmium.
Topics: Animals; Body Weight; Cadmium; Hemagglutination; Immunity; Immunoglobulin G; Immunoglobulin M; Kille | 2000 |
Colloid in the pituitary pars distalis of viscacha (Lagostomus maximus maximus): ultrastructure and occurrence in relation to season, sex, and growth.
Topics: Age Factors; Animals; Body Weight; Colloids; Female; Male; Melatonin; Microscopy, Electron; Neurons; | 2000 |
Triggering of neuroendocrine refractoriness to short-day patterns of melatonin in Siberian hamsters.
Topics: Animals; Body Weight; Cricetinae; Male; Melatonin; Phodopus; Photoperiod; Pineal Gland; Testis | 2000 |
Photic entrainment of circannual rhythms in golden-mantled ground squirrels: role of the pineal gland.
Topics: Animals; Body Weight; Female; Light; Melatonin; Osmolar Concentration; Photoperiod; Pineal Gland; Re | 2000 |
Inhibitory effects of low doses of melatonin on induction of preneoplastic liver lesions in a medium-term liver bioassay in F344 rats: relation to the influence of electromagnetic near field exposure.
Topics: Adrenocorticotropic Hormone; Alkylating Agents; Animals; Biological Assay; Body Weight; Bromodeoxyur | 2000 |
Photoperiodic versus metabolic signals as determinants of seasonal anestrus in the mare.
Topics: Adipose Tissue; Age Factors; Anestrus; Animals; Body Weight; Female; Horses; Leptin; Melatonin; Phot | 2000 |
Influence of melatonin on immunotoxicity of lead.
Topics: Animals; Antioxidants; Body Weight; Flow Cytometry; Immunity, Cellular; Immunoglobulin G; Immunoglob | 2000 |
Determinants of the annual pattern of reproduction in mature male merino and Suffolk sheep: modification of endogenous rhythms by photoperiod.
Topics: Animals; Body Weight; Follicle Stimulating Hormone; Luteinizing Hormone; Male; Melatonin; Photoperio | 1999 |
Preservation of the antioxidant status in chemically-induced diabetes mellitus by melatonin.
Topics: Administration, Oral; Alloxan; Animals; Antioxidants; Blood Glucose; Body Weight; Catalase; Diabetes | 2000 |
Testicular development in Siberian hamsters depends on frequency and pattern of melatonin signals.
Topics: Animals; Body Weight; Cricetinae; Female; Infusions, Intravenous; Light; Male; Melatonin; Organ Size | 2000 |
Gonadotrophin secretion in prepubertal bull calves born in spring and autumn.
Topics: Analysis of Variance; Animals; Body Weight; Cattle; Follicle Stimulating Hormone; Gonadotropins, Pit | 2000 |
Dietary restriction and aging in rhesus monkeys: the University of Wisconsin study.
Topics: Aging; Animals; Behavior, Animal; Blood Glucose; Body Composition; Body Weight; Bone Density; Dehydr | 2000 |
An age-related decline in melatonin secretion is not altered by food restriction.
Topics: Age Factors; Animals; Body Weight; Circadian Rhythm; Food Deprivation; Humans; Male; Melatonin; Mode | 2001 |
Low ambient temperature accelerates short-day responses in Siberian hamsters by altering responsiveness to melatonin.
Topics: Analysis of Variance; Animals; Biological Clocks; Body Weight; Circadian Rhythm; Cold Temperature; C | 2001 |
Melatonin and maturation pace in female three-spined stickleback, Gasterosteus aculeatus.
Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Female; Fishes; Light; Melatonin; Oocytes; O | 2001 |
Chemoprevention of NMU-induced rat mammary carcinoma with the combination of melatonin and 9-cis-retinoic acid.
Topics: Adenocarcinoma; Alitretinoin; Animals; Anticarcinogenic Agents; Antioxidants; Body Weight; Carcinoge | 2001 |
Effects of photoperiod and melatonin on the development of growth hormone cells and the pituitary-adrenal axis in the Djungarian hamster, Phodopus sungorus.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Aging; Animals; Body Weight; Cricetinae; Growth Hormone | 2001 |
Melatonin increases both life span and tumor incidence in female CBA mice.
Topics: Aging; Animals; Body Weight; Brain; Estrus; Female; Free Radicals; Incidence; Liver; Locomotion; Lon | 2001 |
Antioxidant and antiaging activity of N-acetylserotonin and melatonin in the in vivo models.
Topics: Aging; Aldehydes; Animals; Antioxidants; Body Weight; Brain; Female; Glutathione Peroxidase; Kidney; | 2001 |
Vasorelaxant effects of the chronic treatment with melatonin on mesenteric artery and aorta of spontaneously hypertensive rats.
Topics: Acetylcholine; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Body Weight; Calcimycin; Enz | 2001 |
Artificially accelerated aging by shortened photoperiod alters early gene expression (Fos) in the suprachiasmatic nucleus and sulfatoxymelatonin excretion in a small primate, Microcebus murinus.
Topics: Aging; Animals; Body Weight; Cheirogaleidae; Circadian Rhythm; Gene Expression Regulation; Immunohis | 2001 |
Preventive effects of raloxifene and melatonin in N-methyl-N-nitrosourea-induced mammary carcinogenesis in female rats.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Drinking; Eating; Female; Kinetics; Mammary Neoplasms | 2001 |
Effects of pinealectomy on the circadian release pattern of leptin in male rat.
Topics: Animals; Body Weight; Circadian Rhythm; Leptin; Male; Melatonin; Pineal Gland; Rats; Rats, Wistar | 2001 |
Retinal photoreceptors of Syrian hamsters undergo oxidative stress during streptozotocin-induced diabetes.
Topics: Amidines; Animals; Antioxidants; Blood Glucose; Body Weight; Cholesterol; Cricetinae; Diabetes Melli | 2002 |
Effects of maternal-melatonin treatment on open-field behaviors and hypertensive phenotype in spontaneously hypertensive rats' (SHR) offspring.
Topics: Animals; Behavior, Animal; Blood Pressure; Body Weight; Exploratory Behavior; Female; Hypertension; | 2002 |
Testicular and somatic growth in Siberian hamsters depend on the melatonin-free interval between twice daily melatonin signals.
Topics: Animals; Body Weight; Cricetinae; Drug Administration Schedule; Male; Melatonin; Neurosecretory Syst | 2002 |
Seasonal weight regulation of the raccoon dog (Nyctereutes procyonoides): interactions between melatonin, leptin, ghrelin, and growth hormone.
Topics: Adipose Tissue; Animals; Basal Metabolism; Body Weight; Carnivora; Drug Implants; Eating; Energy Met | 2002 |
Absence of pineal-independent mediation of seasonal differences in suprachiasmatic nucleus AVP and VIP mRNA expression in Siberian hamsters.
Topics: Animals; Animals, Newborn; Arginine Vasopressin; Body Weight; Circadian Rhythm; Cricetinae; Female; | 2002 |
Differential regulation of luteinizing hormone and follicle-stimulating hormone in male siberian hamsters by exposure to females and photoperiod.
Topics: Aging; Animals; Body Weight; Cricetinae; Female; Follicle Stimulating Hormone; Gonadotropin-Releasin | 2002 |
Melatonin as an effective protector against doxorubicin-induced cardiotoxicity.
Topics: Animals; Antineoplastic Agents; Apoptosis; Body Weight; Cardiotonic Agents; Creatine Kinase; Cytopro | 2002 |
Melatonin regulates energy balance and attenuates fever in Siberian hamsters.
Topics: Animals; Antioxidants; Body Temperature; Body Weight; Cricetinae; Darkness; Eating; Energy Metabolis | 2002 |
Effects of physiological and pharmacological concentrations of melatonin on ischemia-reperfusion arrhythmias in rats: can the incidence of sudden cardiac death be reduced?
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Body Weight; Death, Sudden, Cardiac; Dose-Response Re | 2002 |
Melatonin induced changes in gonads; pelage and thermogenic characters in the white-footed mouse, Peromyscus leucopus.
Topics: Adipose Tissue, Brown; Animals; Basal Metabolism; Body Temperature Regulation; Body Weight; Female; | 1976 |
Effects of melatonin administration on the reproductive system of the male rat.
Topics: Animals; Body Weight; Female; Follicle Stimulating Hormone; Injections, Subcutaneous; Luteinizing Ho | 1979 |
Use of melatonin and synthetic TRH to determine site of pineal inhibition of TSH secretion.
Topics: Animals; Body Weight; Injections, Intraperitoneal; Injections, Intraventricular; Light; Male; Melato | 1978 |
Induced PKU in rats: effects of age and melatonin treatment.
Topics: Aging; Animals; Animals, Newborn; Behavior, Animal; Body Weight; Female; Humans; Learning; Melatonin | 1977 |
Investigations on seasonal rhythms and the effect of melatonin in the Alpine hare (Lepus timidus timidus L.).
Topics: Animals; Body Weight; Circadian Rhythm; Hair; Light; Male; Melatonin; Organ Size; Rabbits; Seasons; | 1979 |
Prevention by melatonin of short day induced atrophy of the reproductive systems of male and female hamsters.
Topics: Animals; Atrophy; Body Weight; Cricetinae; Dose-Response Relationship, Drug; Female; Follicle Stimul | 1977 |
Antigonadal effects of blinding in the presence of antibody against circulating melatonin.
Topics: Animals; Antigen-Antibody Reactions; Blindness; Body Weight; Genitalia, Male; Luteinizing Hormone; M | 1977 |
The effects of pineal indoles given late in the light period on reproductive organs and pituitary prolactin levels in male golden hamsters.
Topics: Animals; Body Weight; Cricetinae; Genitalia, Male; Indoles; Light; Male; Melatonin; Mesocricetus; Or | 1977 |
Effect of injecting 5-methoxy indoles, pineal compounds, on testicular weight of white leghorn cockerels (Gallus domesticus L.).
Topics: Animals; Body Weight; Chickens; Comb and Wattles; Indoles; Male; Melatonin; Organ Size; Pineal Gland | 1977 |
Influence of melatonin, constant light, or blinding on reproductive system of gerbils (Meriones unguiculatus).
Topics: Animals; Blindness; Body Weight; Female; Genitalia; Gerbillinae; Light; Litter Size; Male; Melatonin | 1976 |
Pineal methoxyindoles: new evidence concerning their function in the control of pineal-mediated changes in the reproductive physiology of male golden hamsters.
Topics: Animals; Body Weight; Cricetinae; Darkness; Gonadotropin-Releasing Hormone; Indoles; Light; Luteiniz | 1975 |
Melatonin-pineal relationships in female golden hamsters.
Topics: Animals; Blindness; Body Weight; Cricetinae; Dogs; Female; Luteinizing Hormone; Melatonin; Organ Siz | 1975 |
A counter antigonadotrophic effect of melatonin in male rats.
Topics: Adrenal Glands; Animals; Blindness; Body Weight; Gonadotropins, Pituitary; Growth; Luteinizing Hormo | 1975 |
Melatonin inhibition of pineal antigonadotrophic activity in male rats.
Topics: Animals; Blindness; Body Weight; Genitalia, Male; Male; Melatonin; Organ Size; Pineal Gland; Pituita | 1975 |
Serum prolactin and luteinizing hormone levels and the activities of hypothalamic monoamine oxidase A and B and phenylethanolamine-N-methyl transferase are changed during sexual maturation in male rats treated neonatally with melatonin.
Topics: Animals; Animals, Newborn; Body Weight; Follicle Stimulating Hormone; Hypothalamus; Luteinizing Horm | 1992 |
Effects of subcutaneous melatonin implants during long daylength on voluntary feed intake, rumen capacity and heart rate of red deer (Cervus elaphus) fed on a forage diet.
Topics: Animal Feed; Animals; Body Weight; Circadian Rhythm; Deer; Drug Implants; Eating; Heart Rate; Male; | 1992 |
Plasma melatonin levels in anorexia nervosa.
Topics: Adolescent; Adult; Anorexia Nervosa; Body Weight; Circadian Rhythm; Female; Humans; Hypoglycemia; Me | 1992 |
Effects of melatonin treatment on the attainment of puberty in heifers.
Topics: Aging; Animals; Body Weight; Cattle; Circadian Rhythm; Drug Implants; Female; Melatonin; Random Allo | 1992 |
Effect of short-term fasting on nocturnal melatonin secretion in obesity.
Topics: Administration, Oral; Adult; Blood Glucose; Body Mass Index; Body Weight; Circadian Rhythm; Fasting; | 1992 |
Melatonin inhibits mammary gland development in female mice.
Topics: Animals; Body Weight; DNA; Female; Mammary Glands, Animal; Melatonin; Mice; Mice, Inbred BALB C; Sex | 1992 |
Interruption of nocturnal pineal melatonin synthesis in spontaneous recrudescent Djungarian hamsters (Phodopus sungorus).
Topics: Animals; Body Weight; Circadian Rhythm; Cricetinae; Male; Melatonin; Phodopus; Photoperiod; Pineal G | 1992 |
Effects of pinealectomy on wool growth and wool follicle density in merino sheep.
Topics: Animals; Body Weight; Castration; Cell Count; Circadian Rhythm; Hair; Male; Melatonin; Pineal Gland; | 1992 |
Late afternoon administration of melatonin is prosomatotrophic and exerts androgen independent effects on erythropoiesis in male house sparrow Passer domesticus.
Topics: Animals; Beak; Birds; Body Weight; Castration; Drug Administration Schedule; Erythropoiesis; Growth; | 1992 |
N-methyl-D-aspartate does not prevent effects of melatonin on the reproductive and thyroid axes of male Syrian hamsters.
Topics: Animals; Body Weight; Cricetinae; Genitalia, Male; Gonadotropins, Pituitary; Male; Melatonin; Mesocr | 1992 |
Endogenous circannual rhythms and photorefractoriness of testis activity, moult and prolactin concentrations in mink (Mustela vison).
Topics: Animals; Body Weight; Circadian Rhythm; Drug Implants; Follicle Stimulating Hormone; Light; Luteiniz | 1992 |
Age-associated changes and sex differences in urinary 6-sulphatoxymelatonin circadian rhythm in the rat.
Topics: Age Factors; Animals; Body Weight; Circadian Rhythm; Estradiol; Female; Male; Melatonin; Radioimmuno | 1992 |
Pattern of pineal melatonin concentrations during prolonged exposure to short photoperiods in photosensitive and photoinsensitive Djungarian hamsters.
Topics: Animals; Body Weight; Circadian Rhythm; Cricetinae; Dark Adaptation; Female; Light; Male; Melatonin; | 1992 |
Effects of photoperiod on the reproductive physiology of male flying foxes, Pteropus poliocephalus.
Topics: Animals; Body Weight; Chiroptera; Circadian Rhythm; Male; Melatonin; Periodicity; Reproduction; Seas | 1992 |
Carbaryl-induced changes in indoleamine synthesis in the pineal gland and its effects on nighttime serum melatonin concentrations.
Topics: 5-Hydroxytryptophan; Acetylserotonin O-Methyltransferase; Animals; Arylamine N-Acetyltransferase; Bo | 1991 |
Melatonin increases serum growth hormone and insulin-like growth factor I (IGF-I) levels in male Syrian hamsters via hypothalamic neurotransmitters.
Topics: Animals; Body Weight; Cricetinae; Growth Hormone; Hydroxyindoleacetic Acid; Hypothalamus; Injections | 1990 |
Effect of oral melatonin treatment on the seasonal physiology of pony stallions.
Topics: Administration, Oral; Animals; beta-Endorphin; Body Weight; Circadian Rhythm; Horses; Hydrocortisone | 1991 |
Effect of melatonin on reproductive system in male rat, treated with estrogen in the first day of life.
Topics: Animals; Body Weight; Epididymis; Estrogens; Genitalia, Male; Male; Melatonin; Organ Size; Prostate; | 1991 |
Plasma melatonin levels in Japanese quail exposed to dim light are determined by subjective interpretation of day and night, not light intensity.
Topics: Animals; Body Weight; Circadian Rhythm; Coturnix; Light; Male; Melatonin | 1991 |
SCN lesions block responses to systemic melatonin infusions in Siberian hamsters.
Topics: Animals; Body Weight; Brain Diseases; Circadian Rhythm; Cricetinae; Follicle Stimulating Hormone; In | 1991 |
Suprachiasmatic and paraventricular control of photoperiodism in Siberian hamsters.
Topics: Analysis of Variance; Animals; Arginine Vasopressin; beta-Endorphin; Body Weight; Brain Diseases; Ci | 1991 |
Pineal and adrenal function before and after refeeding in anorexia nervosa.
Topics: Adrenal Glands; Adult; Anorexia Nervosa; Body Weight; Depressive Disorder; Female; Humans; Hydrocort | 1991 |
Effects of melatonin agonists and antagonists on reproduction and body weight in the Siberian hamster.
Topics: Animals; Binding, Competitive; Body Weight; Cricetinae; Light; Male; Median Eminence; Melatonin; Met | 1990 |
Pattern of LH and testosterone secretion of adult male fallow deer (Dama dama) during the transition into the breeding season.
Topics: Animals; Body Weight; Circadian Rhythm; Deer; Luteinizing Hormone; Male; Melatonin; Neck; Pituitary | 1991 |
The effects of photoperiod and different dosages of melatonin on metamorphic rate and weight gain in Xenopus laevis tadpoles.
Topics: Animals; Body Weight; Larva; Light; Melatonin; Metamorphosis, Biological; Xenopus laevis | 1991 |
Human nocturnal blood melatonin and liver acetylation status.
Topics: Acetylation; Adolescent; Adult; Arylamine N-Acetyltransferase; Body Constitution; Body Weight; Darkn | 1991 |
Effects of melatonin implants on reproductive seasonality of male red deer (Cervus elaphus).
Topics: Animals; Antlers; Biometry; Body Weight; Deer; Hair; Male; Melatonin; Reproduction; Scrotum; Seasons | 1991 |
Reproductive responses of male Microtus montanus to photoperiod, melatonin, and 6-MBOA.
Topics: Analysis of Variance; Animals; Arvicolinae; Benzoxazoles; Body Weight; Drug Combinations; Light; Lut | 1990 |
Factors influencing urinary 6-sulphatoxymelatonin, a major melatonin metabolite, in normal human subjects.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Body Height; Body Weight; Brain Diseases; C | 1990 |
Pineal involvement in the alimentary behavior and taste preferences in the rat.
Topics: Animals; Body Weight; Circadian Rhythm; Drinking Behavior; Feeding Behavior; Food Preferences; Male; | 1990 |
The pineal gland in newborn southern elephant seals, Mirounga leonina.
Topics: Aging; Animals; Animals, Newborn; Body Temperature Regulation; Body Weight; Melatonin; Organ Size; P | 1990 |
Effect of melatonin administration and long day-length on endocrine cycles in the hedgehog Erinaceus europaeus.
Topics: Animals; Body Weight; Hedgehogs; Light; Male; Melatonin; Periodicity; Seasons; Testosterone; Thyroxi | 1990 |
Photoperiod history, melatonin, and reproductive responses of male Syrian hamsters.
Topics: Analysis of Variance; Animals; Body Weight; Circadian Rhythm; Cricetinae; Light; Male; Melatonin; Me | 1990 |
Fluctuation of blood melatonin concentrations with age: result of changes in pineal melatonin secretion, body growth, and aging.
Topics: Age Factors; Aging; Analysis of Variance; Animals; Body Weight; Gas Chromatography-Mass Spectrometry | 1990 |
Effect of melatonin administration and long day-length on endocrine cycles in the hedgehog Erinaceus europaeus.
Topics: Animals; Body Weight; Hedgehogs; Light; Male; Melatonin; Periodicity; Seasons; Testosterone; Thyroxi | 1990 |
Rate of reproductive involution following either exposure to short days or daily administration of melatonin is faster in inbred than in random-bred female Syrian hamsters.
Topics: Animals; Body Weight; Breeding; Cricetinae; Estrus; Female; Follicle Stimulating Hormone; Light; Mel | 1989 |
Undernutrition potentiates melatonin effects in maturing female rats.
Topics: Animals; Body Weight; Estrus; Female; Follicle Stimulating Hormone; Food Deprivation; Luteinizing Ho | 1989 |
Biochemical and ultrastructural approaches to the onset of the pineal melatonin rhythm in the rat.
Topics: Animals; Animals, Suckling; Body Weight; Circadian Rhythm; DNA; Fetus; Melatonin; Microscopy, Electr | 1989 |
Effect of melatonin infusion duration and frequency on gonad, lipid, and body mass in pinealectomized male Siberian hamsters.
Topics: Adipose Tissue; Analysis of Variance; Animals; Body Weight; Circadian Rhythm; Cricetinae; Darkness; | 1989 |
Beta-endorphin and dynorphin mimic the circadian immunoenhancing and anti-stress effects of melatonin.
Topics: Adjuvants, Immunologic; Animals; beta-Endorphin; Body Weight; Circadian Rhythm; Dynorphins; Erythroc | 1989 |
Inherited changes in concentrations of retinal and serum melatonin in the chicken.
Topics: Animals; Blindness; Body Weight; Chickens; Gas Chromatography-Mass Spectrometry; Heterozygote; Homoz | 1989 |
Geographic differences for delay of sexual maturation in Peromyscus leucopus: effects of photoperiod, pinealectomy, and melatonin.
Topics: Animals; Body Weight; Connecticut; Georgia; Light; Male; Melatonin; Organ Size; Periodicity; Peromys | 1989 |
Effects of melatonin and thyroxine treatment on reproductive organs and thyroid hormone levels in male hamsters.
Topics: Animals; Body Weight; Cricetinae; Male; Melatonin; Mesocricetus; Organ Size; Radioimmunoassay; Semin | 1989 |
Effects of daily afternoon melatonin administration on body weight and thyroid hormones in female hamsters.
Topics: Animals; Body Weight; Cricetinae; Drug Administration Schedule; Estrus; Female; Injections, Subcutan | 1989 |
Changes in melatonin levels but not cortisol levels are associated with depression in patients with eating disorders.
Topics: Adolescent; Adult; Anorexia Nervosa; Body Weight; Bulimia; Circadian Rhythm; Depressive Disorder; Fe | 1989 |
Circadian rhythms of melatonin and cortisol in aging.
Topics: Adult; Aged; Aged, 80 and over; Aging; Body Height; Body Weight; Circadian Rhythm; Female; Humans; H | 1989 |
Cortical beta- and alpha 2- adrenoceptor binding, hypothalamic noradrenaline and pineal melatonin concentrations measured at different times of the day after repeated treatment of rats with imipramine, zimeldine, alaproclate and amiflamine.
Topics: Alanine; Animals; Antidepressive Agents; Body Weight; Cerebral Cortex; Circadian Rhythm; Dihydroalpr | 1986 |
Inhibitory effects of the pineal hormone melatonin and underfeeding during the promotional phase of 7,12-dimethylbenzanthracene-(DMBA)-induced mammary tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Cell Transformation, Neoplastic; Female; Foo | 1986 |
A study of sulphatoxymelatonin excretion and gonadotrophin status during weight gain in anorexia nervosa.
Topics: Adult; Anorexia Nervosa; Body Weight; Estradiol; Female; Follicle Stimulating Hormone; Humans; Lutei | 1988 |
Effects of melatonin on long-day responses in short-day housed adult Siberian hamsters.
Topics: Adipose Tissue; Adipose Tissue, Brown; Animals; Body Composition; Body Weight; Circadian Rhythm; Cri | 1988 |
Differential effects of short day pretreatment on melatonin-induced adjustments in Djungarian hamsters.
Topics: Animals; Body Weight; Circadian Rhythm; Cricetinae; Female; Hair Color; Male; Melatonin; Reference V | 1988 |
Daily melatonin injections affect the expression of circadian rhythmicity in Djungarian hamsters kept under a long-day photoperiod.
Topics: Animals; Body Weight; Circadian Rhythm; Cricetinae; Female; Light; Male; Melatonin; Periodicity; Tes | 1988 |
Peak duration of serum melatonin and short-day responses in adult Siberian hamsters.
Topics: Adipose Tissue; Adipose Tissue, Brown; Animals; Body Weight; Circadian Rhythm; Cricetinae; Eating; E | 1988 |
Melatonin secretion and anorexia nervosa--a serious type II error.
Topics: Anorexia Nervosa; Body Weight; Humans; Melatonin | 1988 |
Growth, carcass composition and plasma melatonin in postpubertal beef heifers fed melatonin.
Topics: Animals; Body Composition; Body Weight; Cattle; Female; Light; Melatonin; Muscle Development; Muscle | 1988 |
Melatonin increases serum insulin-like growth factor-I in male Syrian hamsters.
Topics: Animals; Body Weight; Cricetinae; Insulin-Like Growth Factor I; Luteinizing Hormone; Male; Melatonin | 1988 |
Studies on the effects of the pineal hormone melatonin on an androgen-insensitive rat prostatic adenocarcinoma, the Dunning R 3327 HIF tumor.
Topics: Adenocarcinoma; Androgens; Animals; Body Weight; Cell Line; Drug Implants; Male; Melatonin; Olfactor | 1988 |
Melatonin circadian rhythm in anorexia nervosa and obesity.
Topics: Adolescent; Adult; Anorexia Nervosa; Body Weight; Circadian Rhythm; Feeding Behavior; Female; Humans | 1988 |
Cycles of antler and testicular growth in an aseasonal tropical deer (Axis axis).
Topics: Animals; Antlers; Body Weight; Deer; Horns; Male; Melatonin; Seasons; Testis; Testosterone | 1988 |
Influence of pinealectomy on plasma and extrapineal melatonin rhythms in young chickens (Gallus domesticus).
Topics: Animals; Body Weight; Chickens; Circadian Rhythm; Harderian Gland; Hematocrit; Male; Melatonin; Pine | 1987 |
Effect of pinealectomy and a constant high level of circulating melatonin or of 5-methoxytryptamine on the vasopressinergic innervation in the brain of the European hamster (Cricetus cricetus, L).
Topics: 5-Methoxytryptamine; Animals; Body Weight; Brain; Cricetinae; Male; Melatonin; Organ Size; Pineal Gl | 1987 |
Effect of exercise on puberty, periods and pregnancy.
Topics: Amenorrhea; Body Composition; Body Weight; Estrogens; Female; Gonadotropins, Pituitary; Humans; Hypo | 1986 |
Effects of cold, short day and melatonin on thermogenesis, body weight and reproductive organs in Alaskan red-backed voles.
Topics: Animals; Arvicolinae; Body Temperature Regulation; Body Weight; Cold Temperature; Female; Genitalia; | 1986 |
Effect of melatonin on gonads, body weight, and luteinizing hormone (LH) dependent coloration of the Indian finch, Lal munia (Estrilda amandava).
Topics: Animals; Birds; Body Weight; Luteinizing Hormone; Male; Melatonin; Organ Size; Pigmentation; Seasons | 1987 |
Stimulation of food intake and growth of chickens by cyproheptadine: lack of interaction with the effects of pinealectomy and melatonin.
Topics: Animals; Body Weight; Chickens; Cyproheptadine; Eating; Male; Melatonin; Pineal Gland | 1987 |
Annual cycle of liveweight and reproductive changes of farmed male fallow deer (Dama dama) and the effect of daily oral administration of melatonin in summer on the attainment of seasonal fertility.
Topics: Animals; Body Weight; Deer; Fertility; Male; Melatonin; Orchiectomy; Periodicity; Reproduction; Seas | 1987 |
Effect of food restriction on 24-h serum and pineal melatonin content in male rats.
Topics: Animals; Body Weight; Circadian Rhythm; Food; Genitalia, Male; Luteinizing Hormone; Male; Melatonin; | 1987 |
Anti-glucocorticoid effects of melatonin on adult rats.
Topics: Adrenal Glands; Animals; Body Weight; Dexamethasone; Female; Melatonin; Organ Size; Rats; Rats, Inbr | 1987 |
The effect of melatonin administration and short exposures to cold on body temperature of the blind subterranean mole rat (Rodentia, Spalax ehrenberghi, Nehring).
Topics: Animals; Blindness; Body Temperature; Body Temperature Regulation; Body Weight; Cold Temperature; Me | 1986 |
Anti-glucocorticoid effects of melatonin in young rats.
Topics: Adrenal Glands; Animals; Blood Glucose; Body Weight; Dexamethasone; Female; Glucocorticoids; Hydroco | 1986 |
Induction of early breeding in red deer (Cervus elaphus) by melatonin.
Topics: Animals; Body Weight; Breeding; Deer; Female; Lactation; Male; Melatonin; Pregnancy; Reproduction; S | 1986 |
Photoperiod and body weight in female Syrian hamsters: skeleton photoperiods, response magnitude, and development of photorefractoriness.
Topics: Adipose Tissue, Brown; Animals; Body Weight; Cricetinae; Energy Metabolism; Estrus; Female; Light; M | 1986 |
Antigonadal actions of olfactory and light deprivation. II. Effects of pinealectomy or melatonin injections in olfactory bulb deafferented or bulbectomized male rats.
Topics: Animals; Body Weight; Male; Melatonin; Olfactory Bulb; Olfactory Nerve; Organ Size; Pineal Gland; Pi | 1985 |
Seasonal affective disorder and phototherapy.
Topics: Adult; Body Weight; Electroencephalography; Female; Humans; Male; Melatonin; Mood Disorders; Phototh | 1985 |
Seasonal cycles in energy balance: regulation by light.
Topics: Animals; Arvicolinae; Body Composition; Body Water; Body Weight; Energy Metabolism; Female; Light; L | 1985 |
Testicular function and pelage color have different critical daylengths in the Djungarian hamster, Phodopus sungorus sungorus.
Topics: Animals; Body Weight; Castration; Cricetinae; Follicle Stimulating Hormone; Hair Color; Light; Male; | 1985 |
Inhibitory action of exogenous melatonin, 5-methoxytryptamine, and 6-hydroxymelatonin on sexual maturation of male rats: activity of 5-methoxytryptamine might be due to its conversion to melatonin.
Topics: 5-Methoxytryptamine; Acetylation; Animals; Biotransformation; Body Weight; Dose-Response Relationshi | 1985 |
Age- and sex-associated modification of plasma melatonin concentrations in man. Relationship to pathology, malignant or not, and autopsy findings.
Topics: Age Factors; Aged; Alcohol Drinking; Body Weight; Female; Humans; Male; Melatonin; Middle Aged; Neop | 1985 |
Effect of intravaginal implants of melatonin on the onset of ovarian activity in adult and prepubertal ewes.
Topics: Animals; Body Weight; Drug Implants; Female; Melatonin; Ovary; Sexual Maturation; Sheep; Vagina | 1985 |
Stereological studies on the effects of pinealectomy, melatonin and oestradiol on the adrenal cortex of ovariectomised rats.
Topics: Adrenal Cortex; Adrenal Medulla; Animals; Body Weight; Estradiol; Female; Melatonin; Organ Size; Ova | 1985 |
Body weight, food intake and energy regulation in exercising and melatonin-treated Siberian hamsters.
Topics: Adipose Tissue, Brown; Animals; Body Composition; Body Weight; Cricetinae; Eating; Male; Melatonin; | 1985 |
Melatonin: its inhibition of pineal antigonadotrophic activity in male hamsters.
Topics: Animals; Body Weight; Circadian Rhythm; Cricetinae; Darkness; Gonadotropins, Pituitary; Light; Male; | 1974 |
Neonatal melatonin administration and subsequent functioning of adult gonadal and adrenal neuroendocrine axes.
Topics: Adrenal Glands; Adrenalectomy; Animals; Animals, Newborn; Body Weight; Female; Gonads; Male; Melaton | 1974 |
Photoperiod and crowding effects on testicular serotonin metabolism and lack of effects on melatonin synthesis in Uinta ground squirrels (Spermophilus armatus).
Topics: Animals; Body Weight; Carbon Isotopes; Circadian Rhythm; Crowding; Darkness; Environmental Exposure; | 1973 |
Relationship between the pineal gland, other endocrine glands and reproductive organs of single and parabiosed golden hamsters.
Topics: Adrenal Glands; Animals; Blindness; Body Weight; Castration; Cricetinae; Female; Iodine Radioisotope | 1973 |
Melatonin stimulates growth of brown adipose tissue.
Topics: Adipose Tissue, Brown; Animals; Body Weight; Cricetinae; Light; Male; Melatonin; Periodicity; Season | 1974 |
Effect of melatonin and short photoperiod on delta 4-reductase activity in liver and hypothalamus of the hamster and the rat.
Topics: Animals; Body Weight; Cricetinae; Depression, Chemical; Hypothalamus; Light; Liver; Male; Melatonin; | 1974 |
Influence of the pineal gland on gonadal maturation in the Japanese quail.
Topics: Animals; Body Weight; Female; Follicle Stimulating Hormone; Light; Luteinizing Hormone; Male; Melato | 1968 |
Pineal and gonadal function in the rat following cervical sympathectomy.
Topics: Animals; Body Weight; Estrus; Female; Ganglia, Autonomic; Haplorhini; Light; Melatonin; Methyltransf | 1971 |
Hydroxyindole-O-methyl transferase activity of male rat pineal glands following hypophysectomy and HGG treatment.
Topics: Age Factors; Androgens; Animals; Body Weight; Chorionic Gonadotropin; Hypophysectomy; Male; Melatoni | 1972 |
Effect of melatonin upon thyroid hormone secretion rate in female hamsters and male rats.
Topics: Aging; Animals; Body Weight; Cricetinae; Depression, Chemical; Female; Iodine Isotopes; Male; Melato | 1972 |
Evidence for the existence of a pineal-adrenal and a pineal-thyroid axis.
Topics: Adrenal Glands; Animals; Body Weight; DNA; Female; Injections, Intraperitoneal; Melatonin; Organ Siz | 1972 |
Central and peripheral neural pathways necessary for pineal function in the adult female rat.
Topics: Animals; Body Weight; Female; Ganglia, Autonomic; Gonads; Hypothalamus; Light; Limbic System; Melato | 1971 |
[The effect of the pineal hormone, melatonin, on adolescent rats exposed to rhythmic light and dark or to continuous light (author's transl)].
Topics: Adrenal Glands; Animals; Body Weight; Circadian Rhythm; Depression, Chemical; Estrus; Female; Gonado | 1971 |
A comparison of intracerebral and intraperitoneal injections of melatonin and its precursors on 131 I uptake by the thyroid glands of rats.
Topics: 5-Hydroxytryptophan; Animals; Body Weight; Depression, Chemical; Female; Injections; Injections, Int | 1971 |
Effect of treatment with melationin on the pituitary-testicular axis of the male rat.
Topics: Animals; Body Weight; Male; Melatonin; Organ Size; Pituitary Gland; Rats; Seminal Vesicles; Testis | 1970 |
Increase of brain pyridolase phosphokinase activity following melatonin administration.
Topics: Animals; Body Weight; Brain; Brain Chemistry; Female; Melatonin; Phosphotransferases; Proteins; Rats | 1970 |
The effect of pineal methoxyindoles on rat vaginal opening time.
Topics: Adrenal Glands; Animals; Body Weight; Cerebral Ventricles; Female; Follicle Stimulating Hormone; Ind | 1971 |
Melatonin's effect on 131-I uptake by the thyroid glands in normal and ovariectomized rats.
Topics: Animals; Body Weight; Castration; Female; Iodine; Iodine Isotopes; Melatonin; Organ Size; Rats; Thyr | 1968 |
[Physiology of the epiphysis in birds. 3. The effect of melatonin on the sexual development of Coturnix coturnix japonica].
Topics: Animals; Birds; Body Weight; Female; Male; Melatonin; Ovulation; Pineal Gland; Serotonin | 1968 |
[Role of epiphysis in carbohydrate metabolism].
Topics: Adrenalectomy; Animals; Blood Glucose; Body Weight; Carbohydrate Metabolism; Diabetes Mellitus, Expe | 1968 |
Pineal hydroxyindole-O-methyl transferase activity in the growing rat.
Topics: Animals; Body Weight; Carbon Isotopes; Circadian Rhythm; Female; Growth; Male; Melatonin; Methylatio | 1969 |
Pineal gland, melatonin synthesis, and testicular development in the rat.
Topics: Age Factors; Animals; Animals, Newborn; Body Weight; Darkness; Eye; Female; Male; Melatonin; Organ S | 1969 |