melatonin has been researched along with Blood Pressure, Low in 8 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Melatonin (1 and 5 mg/kg) significantly (i) prolonged the survival time of heartstroke rats (117 and 186 min vs 59 min); (ii) attenuated heatstroke-induced hyperthermia and hypotension; (iii) attenuated acute lung injury, including edema, neutrophil infiltration, and hemorrhage scores; (iv) down-regulated exudate volume, BALF PMN cell number, and MPO activity; (v) decreased the BALF levels of lung inflammation response cytokines like TNF-alpha, interleukin (IL)-1β, and IL-6 but further increased the level of an anti-inflammatory cytokine IL-10; (vi) reduced BALF levels of glutamate, lactate-to-pyruvate ratio, NO, 2,3-DHBA, and lactate dehydrogenase." | 7.78 | Melatonin reduces acute lung inflammation, edema, and hemorrhage in heatstroke rats. ( Chang, CK; Chang, CP; Chao, CM; Chou, MT; Lin, MT; Wu, WS, 2012) |
| "Hypotension is a frequent side-effect of cancer biotherapies with cytokines." | 6.68 | Prevention of cytokine-induced hypotension in cancer patients by the pineal hormone melatonin. ( Ardizzoia, A; Barni, S; Braczkowski, R; Brivio, F; Lissoni, P; Maestroni, GJ; Pelizzoni, F; Pittalis, S; Tancini, G; Zubelewicz, B, 1996) |
| "Melatonin (1 and 5 mg/kg) significantly (i) prolonged the survival time of heartstroke rats (117 and 186 min vs 59 min); (ii) attenuated heatstroke-induced hyperthermia and hypotension; (iii) attenuated acute lung injury, including edema, neutrophil infiltration, and hemorrhage scores; (iv) down-regulated exudate volume, BALF PMN cell number, and MPO activity; (v) decreased the BALF levels of lung inflammation response cytokines like TNF-alpha, interleukin (IL)-1β, and IL-6 but further increased the level of an anti-inflammatory cytokine IL-10; (vi) reduced BALF levels of glutamate, lactate-to-pyruvate ratio, NO, 2,3-DHBA, and lactate dehydrogenase." | 3.78 | Melatonin reduces acute lung inflammation, edema, and hemorrhage in heatstroke rats. ( Chang, CK; Chang, CP; Chao, CM; Chou, MT; Lin, MT; Wu, WS, 2012) |
| "Melatonin deprival in young rats induces alterations in cerebral arteriolar wall similar to those observed during aging: atrophy and a decrease in distensibility." | 3.72 | Impact of treatment with melatonin on cerebral circulation in old rats. ( Atkinson, J; Chillon, JM; Delagrange, P; Dupuis, F; Limiñana, P; Régrigny, O; Scalbert, E, 2004) |
| "Hypotension is a frequent side-effect of cancer biotherapies with cytokines." | 2.68 | Prevention of cytokine-induced hypotension in cancer patients by the pineal hormone melatonin. ( Ardizzoia, A; Barni, S; Braczkowski, R; Brivio, F; Lissoni, P; Maestroni, GJ; Pelizzoni, F; Pittalis, S; Tancini, G; Zubelewicz, B, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Cvikova, D | 1 |
| Sutovska, H | 1 |
| Babarikova, K | 1 |
| Molcan, L | 1 |
| Johnson, HE | 1 |
| Dotson, JM | 1 |
| Ellis, CS | 1 |
| Hill, KK | 1 |
| Wu, WS | 1 |
| Chou, MT | 1 |
| Chao, CM | 1 |
| Chang, CK | 1 |
| Lin, MT | 1 |
| Chang, CP | 1 |
| Dupuis, F | 2 |
| Régrigny, O | 3 |
| Atkinson, J | 3 |
| Limiñana, P | 2 |
| Delagrange, P | 3 |
| Scalbert, E | 3 |
| Chillon, JM | 2 |
| Lissoni, P | 1 |
| Pittalis, S | 1 |
| Ardizzoia, A | 1 |
| Brivio, F | 1 |
| Barni, S | 1 |
| Tancini, G | 1 |
| Pelizzoni, F | 1 |
| Maestroni, GJ | 1 |
| Zubelewicz, B | 1 |
| Braczkowski, R | 1 |
| Lartaud-Idjouadiene, I | 1 |
| van de Luit, L | 1 |
| van der Meulen, J | 1 |
| Cleophas, TJ | 1 |
| Zwinderman, AH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Placebo-controlled Randomized Double-blind Trial of Melatonin in Outpatients With COVID-19 Infection[NCT04784754] | Phase 2 | 0 participants (Actual) | Interventional | 2021-04-01 | Withdrawn (stopped due to lack of subject enrollment) | ||
| A Pilot Placebo-controlled Randomized Double-blind Trial of Melatonin in Outpatients With COVID-19 Infection[NCT04474483] | Phase 2 | 8 participants (Actual) | Interventional | 2020-11-06 | Terminated (stopped due to difficult recruitment and complete first visit in person during thne hight of tne pandemic and later not enough subjects) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for melatonin and Blood Pressure, Low
| Article | Year |
|---|---|
Hypotensive effects of melatonin in rats: Focus on the model, measurement, application, and main mechanisms.
Topics: Animals; Blood Pressure; Cardiovascular System; Humans; Hypertension; Hypotension; Melatonin; Mice; | 2022 |
1 trial available for melatonin and Blood Pressure, Low
| Article | Year |
|---|---|
Prevention of cytokine-induced hypotension in cancer patients by the pineal hormone melatonin.
Topics: Administration, Oral; Adult; Aged; Cytokines; Drug Therapy, Combination; Female; Humans; Hypotension | 1996 |
6 other studies available for melatonin and Blood Pressure, Low
| Article | Year |
|---|---|
Severe Hypotension in an Adolescent After a Melatonin Overdose.
Topics: Adolescent; Drug Overdose; Female; Fluid Therapy; Humans; Hypotension; Melatonin; Sleep Initiation a | 2019 |
Melatonin reduces acute lung inflammation, edema, and hemorrhage in heatstroke rats.
Topics: Acute Lung Injury; Animals; Antioxidants; Bronchoalveolar Lavage Fluid; Fever; Heat Stroke; Hemorrha | 2012 |
Melatonin reduces acute lung inflammation, edema, and hemorrhage in heatstroke rats.
Topics: Acute Lung Injury; Animals; Antioxidants; Bronchoalveolar Lavage Fluid; Fever; Heat Stroke; Hemorrha | 2012 |
Melatonin reduces acute lung inflammation, edema, and hemorrhage in heatstroke rats.
Topics: Acute Lung Injury; Animals; Antioxidants; Bronchoalveolar Lavage Fluid; Fever; Heat Stroke; Hemorrha | 2012 |
Melatonin reduces acute lung inflammation, edema, and hemorrhage in heatstroke rats.
Topics: Acute Lung Injury; Animals; Antioxidants; Bronchoalveolar Lavage Fluid; Fever; Heat Stroke; Hemorrha | 2012 |
Impact of treatment with melatonin on cerebral circulation in old rats.
Topics: Aging; Animals; Arterioles; Brain; Cerebrovascular Circulation; Hypotension; Male; Melatonin; Rats; | 2004 |
Melatonin improves cerebral circulation security margin in rats.
Topics: Animals; Blood Pressure; Carbon Dioxide; Cerebrovascular Circulation; Frontal Lobe; Heart Rate; Hemo | 1998 |
Amplified amplitudes of circadian rhythms and nighttime hypotension in patients with chronic fatigue syndrome: improvement by inopamil but not by melatonin.
Topics: Adult; Blood Pressure; Circadian Rhythm; Deoxyepinephrine; Fatigue Syndrome, Chronic; Female; Heart | 1998 |
Cerebral arteriolar structure and function in pinealectomized rats.
Topics: Animals; Arterioles; Cerebrovascular Circulation; Homeostasis; Hypotension; Male; Melatonin; Pineal | 2001 |