Page last updated: 2024-10-19

melatonin and Blindness

melatonin has been researched along with Blindness in 138 studies

Blindness: The inability to see or the loss or absence of perception of visual stimuli. This condition may be the result of EYE DISEASES; OPTIC NERVE DISEASES; OPTIC CHIASM diseases; or BRAIN DISEASES affecting the VISUAL PATHWAYS or OCCIPITAL LOBE.

Research Excerpts

ExcerptRelevanceReference
"This review proposes an overall vision of the protective and therapeutic role of melatonin in breast cancer: from the specific cases of blind women and their reduction of breast cancer incidence to all clinical uses of the sleep hormone in breast cancer."9.22Protective role of melatonin in breast cancer: what we can learn from women with blindness. ( Amé, S; Coliat, P; Mathelin, C; Minella, C; Neuberger, K; Reix, N; Stora, A, 2022)
"The hypothesis is advanced that blindness from an early age may lead to a reduced risk of breast cancer through altered patterns of melatonin secretion by the pineal gland."8.78Breast cancer, blindness and melatonin. ( Coleman, MP; Reiter, RJ, 1992)
"Melatonin has chronobiotic properties in humans."6.40Efficacy of melatonin treatment in jet lag, shift work, and blindness. ( Arendt, J; Deacon, S; Lockley, SW; Middleton, B; Skene, DJ, 1997)
"This review proposes an overall vision of the protective and therapeutic role of melatonin in breast cancer: from the specific cases of blind women and their reduction of breast cancer incidence to all clinical uses of the sleep hormone in breast cancer."5.22Protective role of melatonin in breast cancer: what we can learn from women with blindness. ( Amé, S; Coliat, P; Mathelin, C; Minella, C; Neuberger, K; Reix, N; Stora, A, 2022)
" This article focuses on the following specific neurologic diseases: nocturnal frontal lobe epilepsy and abnormal motor behaviors of epileptic origin, evaluating differential diagnosis with parasomnias; achondroplasia, confirming the crucial role of craniofacial deformity in determining sleep-disordered breathing; neuromuscular diseases, mainly Duchenne's muscular dystrophy and myotonic dystrophy; cerebral palsy, evaluating either the features of sleep architecture and the importance of the respiratory problems associated; headaches, confirming the strict relationships with sleep in terms of neurochemical and neurobehavioral substrates; and finally a review on the effectiveness of melatonin for sleep problems in children with neurologic syndromes and mental retardation, blindness, and epilepsy."4.81Sleep disorders in children with neurologic diseases. ( Bruni, O; Zucconi, M, 2001)
"The hypothesis is advanced that blindness from an early age may lead to a reduced risk of breast cancer through altered patterns of melatonin secretion by the pineal gland."4.78Breast cancer, blindness and melatonin. ( Coleman, MP; Reiter, RJ, 1992)
" Because blindness is associated with a greater incidence of free-running circadian rhythms, we controlled for circadian phase by a measure of melatonin onset timing."3.88Sleep structure in blindness is influenced by circadian desynchrony. ( Aubin, S; Jennum, P; Kupers, R; Nielsen, T; Ptito, M, 2018)
"A possible resetting of pituitary-thyroid axis regulation can occur in blindness after puberty; variations of melatonin secretion could play a role in this."3.69Melatonin and the pituitary-thyroid axis status in blind adults: a possible resetting after puberty. ( Bellastella, A; Carella, C; Criscuolo, T; De Bellis, A; Iorio, S; Parlato, F; Pisano, G; Sinisi, AA; Sinisi, AM; Venditto, T, 1995)
"Caffeine treatment significantly improved daytime alertness at adverse circadian phases (p <0."2.80Caffeine does not entrain the circadian clock but improves daytime alertness in blind patients with non-24-hour rhythms. ( Lockley, SW; St Hilaire, MA, 2015)
"When melatonin treatment ceased, cortisol and aMT6s rhythms free ran at a similar period to before treatment."2.71The effects of low-dose 0.5-mg melatonin on the free-running circadian rhythms of blind subjects. ( Arendt, J; Hack, LM; Lockley, SW; Skene, DJ, 2003)
"This condition causes recurrent insomnia and daytime sleepiness when the rhythms drift out of phase with the normal 24-hour cycle."2.69Entrainment of free-running circadian rhythms by melatonin in blind people. ( Brandes, RW; Kendall, AR; Lewy, AJ; Sack, RL, 2000)
"Oral melatonin therapy was used to treat-severe circadian sleep-wake disturbances in eight children and young adults in an open study."2.68Long-term melatonin treatment in blind children and young adults with circadian sleep-wake disturbances. ( Blennow, G; Palm, L; Wetterberg, L, 1997)
"Melatonin has been shown to correct the underlying circadian rhythm abnormality as well as improve sleep and reduce daytime napping."2.44Circadian rhythm sleep disorders in the blind and their treatment with melatonin. ( Arendt, J; Skene, DJ, 2007)
"Melatonin clearly has the ability to induce sleepiness and lower core body temperature during "biological day" and to change the timing of human rhythms when treatment is appropriately timed."2.43Melatonin: characteristics, concerns, and prospects. ( Arendt, J, 2005)
"Melatonin is the treatment of choice for blind people with non-24 h sleep/wake disorder."2.42Optimization of light and melatonin to phase-shift human circadian rhythms. ( Skene, DJ, 2003)
"Melatonin has chronobiotic properties in humans."2.40Efficacy of melatonin treatment in jet lag, shift work, and blindness. ( Arendt, J; Deacon, S; Lockley, SW; Middleton, B; Skene, DJ, 1997)
"Melatonin treatment has also been evaluated in the circadian sleep disorders: delayed sleep phase syndrome (DSPS) and non-24-hour sleep wake disorder."2.40Use of melatonin in the treatment of phase shift and sleep disorders. ( Arendt, J; Lockley, SW; Skene, DJ, 1999)
"Treatment with melatonin prevented premature aging and tumorigenesis in rodents."1.38Light-at-night-induced circadian disruption, cancer and aging. ( Anisimov, VN; Panchenko, AV; Popovich, IG; Vinogradova, IA; Zabezhinski, MA, 2012)
"The possibility that a portion of the breast cancer burden might be explained by the introduction and increasing use of electricity to light the night was suggested >20 years ago."1.35Light-at-night, circadian disruption and breast cancer: assessment of existing evidence. ( Stevens, RG, 2009)
"Melatonin was analysed in the saliva by radioimmunoassay after exposure to light (600 lux for 1 hour) (nocturnal melatonin suppression test)."1.35[Alterations in nocturnal melatonin secretion in patients with optic neuropathies]. ( Arribas-Gómez, I; Blanco, R; de la Villa, P; Germain, F; Paz-Moreno, J; Pérez-Rico, C, 2009)
" The resulting log-linear dose-response curve in the physiological range adds support for a circadian function of endogenous melatonin in humans."1.33Melatonin entrains free-running blind people according to a physiological dose-response curve. ( Emens, JS; Jackman, AR; Lefler, BJ; Lewy, AJ; Yuhas, K, 2005)
"Congenital blindness, acquired blindness, presence of bilateral prosthetic eyes or presence of normal human eyes did not produce different nocturnal sleep and 'free-running' pattern results."1.31Sleep/wake cycles in the dark: sleep recorded by polysomnography in 26 totally blind subjects compared to controls. ( Guilleminault, C; Leger, D; Paillard, M; Santos, C, 2002)
"The melatonin onset was used as the indicator of circadian phase."1.31Effects of aging on the intrinsic circadian period of totally blind humans. ( Kendall, AR; Lewy, AJ; Sack, RL, 2001)
"Melatonin is a promising treatment alternative for serious sleep problems in blind children."1.31[Melatonin treatment of a blind child with serious sleep disorders]. ( Loge, JH; Ramstad, K, 2002)
"Melatonin rhythms were assessed in 49 registered blind individuals by measurement of the urinary metabolite of melatonin, 6-sulfatoxymelatonin (aMT6s)."1.30Relationship between melatonin rhythms and visual loss in the blind. ( Arendt, J; Bird, AC; Defrance, R; Lockley, SW; Skene, DJ; Tabandeh, H, 1997)
"Melatonin is a hormone primarily produced by the pineal gland at night and is suppressed by exposure to light."1.30Reduced cancer incidence among the blind. ( Ahlbom, A; Feychting, M; Osterlund, B, 1998)
"24 hr) by chronic administration of melatonin."1.28Feedback in the rabbit's central circadian system, revealed by the changes in its free-running food intake pattern induced by blinding, cervical sympathectomy, pinealectomy, and melatonin administration. ( Bobbert, AC; Riethoven, JJ, 1991)
"A 9-year-old, blind boy with severe mental retardation with a chronic sleep/wake disturbance had a circadian rhythm of 24."1.28Correction of non-24-hour sleep/wake cycle by melatonin in a blind retarded boy. ( Blennow, G; Palm, L; Wetterberg, L, 1991)
"Melatonin-treated mole rats exhibited reduction both in initial body temperature (Tbo) and in the decrease of body temperature (delta Tb) after 6 hours of exposure to cold."1.27The effect of melatonin administration and short exposures to cold on body temperature of the blind subterranean mole rat (Rodentia, Spalax ehrenberghi, Nehring). ( Beiles, A; Heth, G; Nevo, E; Pevet, P, 1986)
"The minimal dosage of melatonin required to inhibit pineal antigonad otropic activity was ascertained in blinded male golden hamsters."1.25Studies on the minimal dosage of melatonin required to inhibit pineal antigonadotrophic activity in male golden hamsters. ( Reiter, RJ; Vaughan, MK; Waring, PJ, 1975)

Research

Studies (138)

TimeframeStudies, this research(%)All Research%
pre-199057 (41.30)18.7374
1990's42 (30.43)18.2507
2000's29 (21.01)29.6817
2010's8 (5.80)24.3611
2020's2 (1.45)2.80

Authors

AuthorsStudies
Minella, C1
Coliat, P1
Amé, S1
Neuberger, K1
Stora, A1
Mathelin, C1
Reix, N1
Atan, YS1
Subaşı, M1
Güzel Özdemir, P1
Batur, M1
Aubin, S2
Jennum, P2
Nielsen, T1
Kupers, R2
Ptito, M2
Hull, JT1
Czeisler, CA7
Lockley, SW11
Hartley, S1
Dauvilliers, Y1
Quera-Salva, MA1
St Hilaire, MA1
Emens, JS8
Eastman, CI1
Stevens, RG1
Pérez-Rico, C1
de la Villa, P1
Blanco, R1
Germain, F1
Paz-Moreno, J1
Arribas-Gómez, I1
Emens, J3
Lewy, AJ21
Laurie, AL1
Songer, JB1
Anisimov, VN1
Vinogradova, IA1
Panchenko, AV1
Popovich, IG1
Zabezhinski, MA1
Leger, D1
Guilleminault, C1
Santos, C1
Paillard, M1
Klerman, EB4
Shanahan, TL3
Brotman, DJ2
Rimmer, DW2
Rizzo, JF3
Skene, DJ11
Sack, RL14
Hasler, BP4
Bernert, RA3
Hack, LM1
Arendt, J15
Fischer, S1
Smolnik, R1
Herms, M1
Born, J1
Fehm, HL1
Lefler, BJ3
Yuhas, K2
Jackman, AR1
Jackman, A1
Nunes, Oda S1
Pereira, Rde S1
Dijk, DJ3
Kosti, O1
Smith, JA1
O'Hara, J1
Schiff, AA1
Niles, LP4
Brown, GM4
Chambers, JW1
Pang, SF4
Karsch, FJ1
Bittman, EL1
Foster, DL1
Goodman, RL1
Legan, SJ1
Robinson, JE1
Blask, DE3
Leadem, CA1
Stockmeier, CA1
Petterborg, LJ2
Paull, WK1
Gibbs, FP2
Vriend, J5
Chanda, S2
Biswas, NM2
Newsome, DA1
Rollag, MD1
Dipinto, MN1
Stetson, MH1
Vaughan, MK7
Powanda, MC1
Brainard, GC1
Johnson, LY1
Reiter, RJ17
Vaughan, GM3
Seraile, LG1
Chen, HJ1
Trakulrungsi, C1
Trakulrungsi, WK1
Lockley, S1
Tabandeh, H3
Skene, D2
Buttery, R1
Bird, A1
Defrace, R1
Ito, J1
Saijo, H1
Tanaka, H1
Tasaki, T1
Chou, K1
Lapierre, O1
Dumont, M1
Moore, RY3
Martens, H2
Klein, T2
Jan, JE2
Espezel, H1
Appleton, RE1
Kronauer, RE2
Seely, EW1
Partonen, T1
Vakkuri, O1
Lamberg-Allardt, C1
Bellastella, A2
Sinisi, AA2
Criscuolo, T2
De Bellis, A2
Carella, C2
Iorio, S2
Sinisi, AM1
Parlato, F1
Venditto, T1
Pisano, G2
Honma, S1
Kanematsu, N1
Katsuno, Y1
Honma, K1
Matsumoto, M1
Blood, ML3
Bird, AC2
Defrance, R2
Stoerig, P1
Cowey, A1
Valdizán-Usón, JR1
Romero, F1
Almárcegui, MC1
Palm, L2
Blennow, G2
Wetterberg, L2
Middleton, B1
Deacon, S1
Hätönen, T1
Laakso, ML1
Heiskala, H1
Alila-Johansson, A1
Sainio, K1
Santavuori, P1
Hahn, RA1
Feychting, M1
Osterlund, B1
Ahlbom, A1
Jagota, A1
Olcese, J1
Harinarayana Rao, S1
Gupta, PD1
Butler, LJ1
James, K2
Thapan, K1
Wright, J2
Amato, G1
Bizzaro, A1
Muccitelli, VI1
Joshi, BN1
Udaykumar, K1
Brandes, RW1
Kendall, AR3
Zeitzer, JM1
Duffy, JF1
Khalsa, SB1
Bauer, VK1
Pires, ML1
Zucconi, M1
Bruni, O1
Laitinen, JT1
Porkka-Heiskanen, T1
Ramstad, K1
Loge, JH1
Bush, FM2
Seibel, HR3
Anderson, GR1
Sackman, JW1
Grota, LJ3
Chakraborty, J1
Sanyal, S1
Bhargava, HN1
Jain, AK1
Knigge, KM1
Sheridan, MN1
Kinson, GA2
Wilson, DA1
Rudeen, PK1
Waring, PJ2
Banks, AF1
Ralph, CL2
Binkley, S1
MacBride, SE1
Klein, DC2
Chazov, EI1
Veselova, SP1
Krivosheev, OG1
Isachenkov, VA1
Takahashi, K1
Katoh, Y1
Sugishita, M1
Takeuchi, Y1
Takashima, M1
Tzischinsky, O2
Pal, I1
Epstein, R2
Dagan, Y1
Lavie, P2
Nakagawa, H3
Coleman, MP1
Keith, LD2
Isaki, K1
Stevenson, J1
Bobbert, AC1
Riethoven, JJ1
Stehle, J1
Reuss, S1
Riemann, R1
Seidel, A1
Vollrath, L1
Chan, YS1
Cheung, YM1
Folkard, S1
Aldhous, M2
Kennett, H1
Cheng, KM1
Allen, AE1
Tsang, CW1
Wong, CO1
Nichols, CR1
Diaz López, B1
Menéndez Patterson, A1
Marín Fernandez, B1
Cassone, VM1
Roberts, MH1
Heth, G1
Pevet, P1
Nevo, E1
Beiles, A1
Rom-Bugoslavskaia, ES1
Thliveris, JA1
Blum, K2
Wallace, JE2
Merritt, JH2
Collu, R1
Fraschini, F1
Nagle, CA1
Cardinali, DP1
Rosner, JM1
Schweisthal, MR1
Murphy, BD1
James, DA1
Weller, JL1
Mull, D1
Lynch, HJ1
Hedlund, L1
Ota, M1
Obara, K1
Peat, F1
Anton-Tay, F1
Wurtman, RJ2
Brownstein, MJ1
Heller, A2
Bhatnager, RK1
Axelrod, J1
Reed, BL1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Regulating Mood and Suicidal Ideation With Morning Light Exposure Treatment[NCT05616819]480 participants (Anticipated)Interventional2023-03-01Not yet recruiting
Characterization of Endogenous Melatonin Profiles in Children With Autism Spectrum Disorder.[NCT00691080]58 participants (Actual)Observational2007-09-30Completed
Melatonin Entrainment of Elderly Blind Free-runners[NCT00692094]12 participants (Actual)Interventional2004-08-31Terminated (stopped due to Unique provision in the American Recovery and Reinvestment Act prevented approval of second year no-cost-extension in which completion of analyses were planned.)
Melatonin Studies of Blind Children[NCT00691444]10 participants (Actual)Interventional2002-09-30Terminated (stopped due to Unique provision in the American Recovery and Reinvestment Act prevented approval of second year no-cost-extension in which completion of analyses were planned.)
Identification of Free-Running Rhythms in Blind Children[NCT00688935]9 participants (Actual)Interventional2005-01-31Terminated (stopped due to Unique provision in the American Recovery and Reinvestment Act prevented approval of second year no-cost-extension in which completion of analyses were planned.)
Operational Evaluation of a Photic Countermeasure to Improve Alertness, Performance, and Mood During Nightshift Work on a 105-day Simulated Human Exploration Mission to Mars[NCT01169233]25 participants (Actual)Interventional2008-08-31Completed
Effects of Bright Light Treatment on Daytime Sleepiness and Nocturnal Sleep in Patients With Parkinson's Disease[NCT01338649]27 participants (Actual)Interventional2007-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in the Epworth Sleepiness Scale (ESS) Scores Comparing the Bright Light Exposure With Dim-red Light Exposure.

ESS score range is 0-24; lower ESS scores indicate less daytime sleepiness; higher ESS scores indicate more severe sleepiness ESS will be taken and compared at screening and week 4 visits between the bright light exposure and dim-red light exposure groups. (NCT01338649)
Timeframe: baseline and 4 weeks

Interventionscore (Mean)
Bright White4.46
Dim Red Light1.77

Reviews

23 reviews available for melatonin and Blindness

ArticleYear
Protective role of melatonin in breast cancer: what we can learn from women with blindness.
    Cancer causes & control : CCC, 2022, Volume: 33, Issue:1

    Topics: Animals; Blindness; Breast Neoplasms; Female; Humans; Incidence; Melatonin; Prospective Studies

2022
Circadian Rhythm Disturbances in the Blind.
    Current neurology and neuroscience reports, 2018, 08-06, Volume: 18, Issue:10

    Topics: Blindness; Circadian Rhythm; Humans; Melatonin; Sleep; Sleep Disorders, Circadian Rhythm; Sleep Wake

2018
Diagnosis and Treatment of Non-24-h Sleep-Wake Disorder in the Blind.
    Drugs, 2017, Volume: 77, Issue:6

    Topics: Benzofurans; Blindness; Circadian Clocks; Cyclopropanes; Humans; Melatonin; Sleep Wake Disorders

2017
Optimization of light and melatonin to phase-shift human circadian rhythms.
    Journal of neuroendocrinology, 2003, Volume: 15, Issue:4

    Topics: Blindness; Chronobiology Disorders; Circadian Rhythm; Humans; Light; Melatonin; Phototherapy; Sleep

2003
Melatonin: characteristics, concerns, and prospects.
    Journal of biological rhythms, 2005, Volume: 20, Issue:4

    Topics: Blindness; Body Temperature; Circadian Rhythm; Humans; Melatonin; Sleep; Vision, Ocular; Wakefulness

2005
Circadian uses of melatonin in humans.
    Chronobiology international, 2006, Volume: 23, Issue:1-2

    Topics: Blindness; Circadian Rhythm; Humans; Melatonin; Periodicity; Seasonal Affective Disorder; Seasons; S

2006
Circadian rhythm sleep disorders in the blind and their treatment with melatonin.
    Sleep medicine, 2007, Volume: 8, Issue:6

    Topics: Blindness; Chronotherapy; Circadian Rhythm; Humans; Melatonin; Sleep; Sleep Disorders, Circadian Rhy

2007
Melatonin and human chronobiology.
    Cold Spring Harbor symposia on quantitative biology, 2007, Volume: 72

    Topics: Blindness; Chronobiology Phenomena; Circadian Rhythm; Dose-Response Relationship, Drug; Female; Huma

2007
Neuroendocrine basis of seasonal reproduction.
    Recent progress in hormone research, 1984, Volume: 40

    Topics: Animals; Blindness; Castration; Estradiol; Estrus; Feedback; Female; Gonadotropin-Releasing Hormone;

1984
Blindsight in man and monkey.
    Brain : a journal of neurology, 1997, Volume: 120 ( Pt 3)

    Topics: Animals; Blindness; Geniculate Bodies; Haplorhini; Humans; Melatonin; Nystagmus, Optokinetic; Photic

1997
[Meta-analysis: trials with melatonin and its effect on the sleep. Letter].
    Revista de neurologia, 1997, Volume: 25, Issue:138

    Topics: Blindness; Circadian Rhythm; Humans; Melatonin; Sleep

1997
Melatonin as a chronobiotic: treatment of circadian desynchrony in night workers and the blind.
    Journal of biological rhythms, 1997, Volume: 12, Issue:6

    Topics: Blindness; Circadian Rhythm; Humans; Melatonin; Work Schedule Tolerance

1997
Efficacy of melatonin treatment in jet lag, shift work, and blindness.
    Journal of biological rhythms, 1997, Volume: 12, Issue:6

    Topics: Animals; Blindness; Circadian Rhythm; Humans; Melatonin; Travel; Work Schedule Tolerance

1997
Does blindness protect against cancers?
    Epidemiology (Cambridge, Mass.), 1998, Volume: 9, Issue:5

    Topics: Blindness; Humans; Incidence; Melatonin; Neoplasms

1998
Light, blindness and endocrine secretions.
    Journal of endocrinological investigation, 1999, Volume: 22, Issue:11

    Topics: Animals; Blindness; Circadian Rhythm; Female; Gonads; Hormones; Humans; Light; Male; Melatonin; Pine

1999
Use of melatonin in the treatment of phase shift and sleep disorders.
    Advances in experimental medicine and biology, 1999, Volume: 467

    Topics: Blindness; Circadian Rhythm; Humans; Jet Lag Syndrome; Melatonin; Sleep Wake Disorders; Work Schedul

1999
Physiological effects of light on the human circadian pacemaker.
    Seminars in perinatology, 2000, Volume: 24, Issue:4

    Topics: Adult; Blindness; Circadian Rhythm; Humans; Light; Melatonin; Pineal Gland; Suprachiasmatic Nucleus;

2000
Sleep disorders in children with neurologic diseases.
    Seminars in pediatric neurology, 2001, Volume: 8, Issue:4

    Topics: Anticonvulsants; Blindness; Child; Child, Preschool; Diagnosis, Differential; Epilepsy; Headache; Hu

2001
[Physiology of the biological clock and the relation of circadian rhythm disorders to illnesses].
    Duodecim; laaketieteellinen aikakauskirja, 1999, Volume: 115, Issue:5

    Topics: Animals; Biological Clocks; Blindness; Chronobiology Disorders; Humans; Jet Lag Syndrome; Light; Mel

1999
Pineal factors in the control of testicular function.
    Advances in sex hormone research, 1976, Volume: 2

    Topics: Androgens; Animals; Blindness; Cricetinae; Fertility; Gonadotropins, Pituitary; Hydroxysteroid Dehyd

1976
Breast cancer, blindness and melatonin.
    European journal of cancer (Oxford, England : 1990), 1992, Volume: 28, Issue:2-3

    Topics: Blindness; Breast Neoplasms; Female; Humans; Male; Melatonin

1992
[The pineal body and the thyroid gland].
    Vestnik Akademii meditsinskikh nauk SSSR, 1985, Issue:8

    Topics: Animals; Blindness; Circadian Rhythm; Cricetinae; Female; Humans; Hyperthyroidism; Hypothyroidism; M

1985
The pineal gland--a neuroendocrine transducer.
    Advances in metabolic disorders, 1972, Volume: 6

    Topics: Adrenal Glands; Blindness; Brain; Electroencephalography; Female; Genitalia; Gonadotropins; Growth;

1972

Trials

15 trials available for melatonin and Blindness

ArticleYear
Caffeine does not entrain the circadian clock but improves daytime alertness in blind patients with non-24-hour rhythms.
    Sleep medicine, 2015, Volume: 16, Issue:6

    Topics: Affect; Aged; Arousal; Blindness; Caffeine; Circadian Clocks; Humans; Male; Melatonin; Middle Aged;

2015
The effects of low-dose 0.5-mg melatonin on the free-running circadian rhythms of blind subjects.
    Journal of biological rhythms, 2003, Volume: 18, Issue:5

    Topics: Adult; Aged; Blindness; Circadian Rhythm; Female; Humans; Hydrocortisone; Male; Melatonin; Middle Ag

2003
Melatonin acutely improves the neuroendocrine architecture of sleep in blind individuals.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:11

    Topics: Adjuvants, Immunologic; Adolescent; Adrenocorticotropic Hormone; Adult; Blindness; Cross-Over Studie

2003
Regression of herpes viral infection symptoms using melatonin and SB-73: comparison with Acyclovir.
    Journal of pineal research, 2008, Volume: 44, Issue:4

    Topics: Acyclovir; Adult; Antiviral Agents; Blindness; Central Nervous System Depressants; Female; Herpes Ge

2008
Suppression of melatonin secretion in some blind patients by exposure to bright light.
    The New England journal of medicine, 1995, Jan-05, Volume: 332, Issue:1

    Topics: Adolescent; Adult; Aged; Blindness; Circadian Rhythm; Female; Humans; Light; Male; Melatonin; Middle

1995
The treatment of sleep disorders with melatonin.
    Developmental medicine and child neurology, 1994, Volume: 36, Issue:2

    Topics: Adolescent; Blindness; Child; Child, Preschool; Chronic Disease; Circadian Rhythm; Disabled Persons;

1994
Effects of exposure to morning bright light in the blind and sighted controls.
    Clinical physiology (Oxford, England), 1995, Volume: 15, Issue:6

    Topics: Adult; Affect; Aged; Blindness; Body Temperature; Calcifediol; Female; Humans; Light; Male; Melatoni

1995
The amplitude of endogenous melatonin production is not affected by melatonin treatment in humans.
    Journal of pineal research, 1997, Volume: 22, Issue:1

    Topics: Adult; Blindness; Female; Humans; Male; Melatonin; Middle Aged; Photoperiod; Work Schedule Tolerance

1997
Relationship between napping and melatonin in the blind.
    Journal of biological rhythms, 1997, Volume: 12, Issue:1

    Topics: Adult; Aged; Aging; Blindness; Circadian Rhythm; Female; Humans; Male; Melatonin; Middle Aged; Sleep

1997
Long-term melatonin treatment in blind children and young adults with circadian sleep-wake disturbances.
    Developmental medicine and child neurology, 1997, Volume: 39, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Age Factors; Blindness; Body Temperature; Child; Child, Pre

1997
Bright light suppresses melatonin in blind patients with neuronal ceroid-lipofuscinoses.
    Neurology, 1998, Volume: 50, Issue:5

    Topics: Adolescent; Adult; Age of Onset; Blindness; Child; Child, Preschool; Female; Humans; Infant; Light;

1998
Melatonin administration can entrain the free-running circadian system of blind subjects.
    The Journal of endocrinology, 2000, Volume: 164, Issue:1

    Topics: Adult; Biomarkers; Blindness; Circadian Rhythm; Humans; Hydrocortisone; Male; Melatonin; Middle Aged

2000
Entrainment of free-running circadian rhythms by melatonin in blind people.
    The New England journal of medicine, 2000, Oct-12, Volume: 343, Issue:15

    Topics: Adult; Blindness; Circadian Rhythm; Cross-Over Studies; Dyssomnias; Female; Humans; Male; Melatonin;

2000
Entrainment of free-running circadian rhythms by melatonin in blind people.
    The New England journal of medicine, 2000, Oct-12, Volume: 343, Issue:15

    Topics: Adult; Blindness; Circadian Rhythm; Cross-Over Studies; Dyssomnias; Female; Humans; Male; Melatonin;

2000
Entrainment of free-running circadian rhythms by melatonin in blind people.
    The New England journal of medicine, 2000, Oct-12, Volume: 343, Issue:15

    Topics: Adult; Blindness; Circadian Rhythm; Cross-Over Studies; Dyssomnias; Female; Humans; Male; Melatonin;

2000
Entrainment of free-running circadian rhythms by melatonin in blind people.
    The New England journal of medicine, 2000, Oct-12, Volume: 343, Issue:15

    Topics: Adult; Blindness; Circadian Rhythm; Cross-Over Studies; Dyssomnias; Female; Humans; Male; Melatonin;

2000
Pretreatment circadian period in free-running blind people may predict the phase angle of entrainment to melatonin.
    Neuroscience letters, 2001, Nov-09, Volume: 313, Issue:3

    Topics: Area Under Curve; Biological Clocks; Blindness; Chronobiology Disorders; Circadian Rhythm; Drug Admi

2001
Melatonin administration to blind people: phase advances and entrainment.
    Journal of biological rhythms, 1991,Fall, Volume: 6, Issue:3

    Topics: Adult; Blindness; Circadian Rhythm; Double-Blind Method; Humans; Hydrocortisone; Male; Melatonin; Sl

1991

Other Studies

100 other studies available for melatonin and Blindness

ArticleYear
The Effect of Blindness on Biological Rhythms and the Consequences of Circadian Rhythm Disorder.
    Turkish journal of ophthalmology, 2023, 04-20, Volume: 53, Issue:2

    Topics: Blindness; Humans; Melatonin; Periodicity; Sleep Disorders, Circadian Rhythm

2023
Sleep structure in blindness is influenced by circadian desynchrony.
    Journal of sleep research, 2018, Volume: 27, Issue:1

    Topics: Adult; Biomarkers; Blindness; Circadian Rhythm; Female; Humans; Male; Melatonin; Middle Aged; Sleep

2018
Suppression of Melatonin Secretion in Totally Visually Blind People by Ocular Exposure to White Light: Clinical Characteristics.
    Ophthalmology, 2018, Volume: 125, Issue:8

    Topics: Adult; Aged; Biomarkers; Blindness; Circadian Rhythm; Female; Humans; Male; Melatonin; Middle Aged;

2018
Melatonin and cortisol profiles in the absence of light perception.
    Behavioural brain research, 2017, 01-15, Volume: 317

    Topics: Adult; Area Under Curve; Blindness; Circadian Rhythm; Female; Humans; Hydrocortisone; Light; Male; M

2017
Light-at-night, circadian disruption and breast cancer: assessment of existing evidence.
    International journal of epidemiology, 2009, Volume: 38, Issue:4

    Topics: Animals; Blindness; Breast Neoplasms; Chronobiology Disorders; Circadian Rhythm; Disease Models, Ani

2009
[Alterations in nocturnal melatonin secretion in patients with optic neuropathies].
    Archivos de la Sociedad Espanola de Oftalmologia, 2009, Volume: 84, Issue:5

    Topics: Afferent Pathways; Aged; Blindness; Case-Control Studies; Circadian Rhythm; Electroretinography; Fem

2009
Rest-activity cycle and melatonin rhythm in blind free-runners have similar periods.
    Journal of biological rhythms, 2010, Volume: 25, Issue:5

    Topics: Actigraphy; Activity Cycles; Adolescent; Adult; Aged; Biological Clocks; Blindness; Child; Circadian

2010
Light-at-night-induced circadian disruption, cancer and aging.
    Current aging science, 2012, Volume: 5, Issue:3

    Topics: Age Factors; Aging; Animals; Anticarcinogenic Agents; Blindness; Cell Transformation, Neoplastic; Ci

2012
Sleep/wake cycles in the dark: sleep recorded by polysomnography in 26 totally blind subjects compared to controls.
    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2002, Volume: 113, Issue:10

    Topics: Adult; Blindness; Darkness; Female; Humans; Male; Marital Status; Melatonin; Middle Aged; Occupation

2002
Photic resetting of the human circadian pacemaker in the absence of conscious vision.
    Journal of biological rhythms, 2002, Volume: 17, Issue:6

    Topics: Adult; Aged; Blindness; Circadian Rhythm; Female; Humans; Light; Male; Melatonin; Middle Aged

2002
Zeitgeber hierarchy in humans: resetting the circadian phase positions of blind people using melatonin.
    Chronobiology international, 2003, Volume: 20, Issue:5

    Topics: Adult; Blindness; Circadian Rhythm; Female; Humans; Male; Melatonin; Middle Aged; Models, Biological

2003
Eventual entrainment of the human circadian pacemaker by melatonin is independent of the circadian phase of treatment initiation: clinical implications.
    Journal of biological rhythms, 2004, Volume: 19, Issue:1

    Topics: Adult; Aged; Animals; Biological Clocks; Blindness; Chronobiology Disorders; Circadian Rhythm; Femal

2004
Relative coordination to unknown "weak zeitgebers" in free-running blind individuals.
    Journal of biological rhythms, 2005, Volume: 20, Issue:2

    Topics: Adult; Blindness; Circadian Rhythm; Female; Humans; Light; Male; Melatonin; Middle Aged; Running; Sa

2005
Melatonin entrains free-running blind people according to a physiological dose-response curve.
    Chronobiology international, 2005, Volume: 22, Issue:6

    Topics: Aged; Blindness; Circadian Rhythm; Dose-Response Relationship, Drug; Female; Humans; Male; Melatonin

2005
Alertness, mood and performance rhythm disturbances associated with circadian sleep disorders in the blind.
    Journal of sleep research, 2008, Volume: 17, Issue:2

    Topics: Adult; Affect; Aged; Arousal; Attention; Blindness; Choice Behavior; Circadian Rhythm; Female; Human

2008
Altered diurnal serum melatonin rhythm in blind men.
    Lancet (London, England), 1981, Oct-24, Volume: 2, Issue:8252

    Topics: Blindness; Circadian Rhythm; Humans; Male; Melatonin; Pineal Gland

1981
Effects of P-chlorophenylalanine on pineal and endocrine function in the rat.
    Pharmacological research communications, 1984, Volume: 16, Issue:9

    Topics: Adrenal Glands; Animals; Blindness; Brain Chemistry; Corticosterone; Endocrine Glands; Fenclonine; G

1984
Differential responsiveness of the reproductive system of blind or melatonin-treated male hamsters to injections of gonadotrophin-releasing hormone (GnRH) and/or prolactin.
    Journal of pineal research, 1984, Volume: 1, Issue:2

    Topics: Animals; Blindness; Body Weight; Cricetinae; Drug Interactions; Genitalia, Male; Gonadotropin-Releas

1984
An immunocytochemical study of the luteinizing hormone-releasing hormone (LHRH) system in the white-footed mouse: effect of blinding and melatonin.
    Journal of pineal research, 1984, Volume: 1, Issue:4

    Topics: Animals; Blindness; Female; Gonadotropin-Releasing Hormone; Histocytochemistry; Hypothalamus; Immuno

1984
Counterantigonadotropic effect of melatonin administered via the drinking water.
    Endocrinology, 1983, Volume: 113, Issue:4

    Topics: Animals; Blindness; Cricetinae; Dose-Response Relationship, Drug; Drinking; Male; Melatonin; Mesocri

1983
Progonadal effect of melatonin on dark exposed or blinded male toads, Bufo melanostictus.
    Folia biologica, 1983, Volume: 31, Issue:3

    Topics: Animals; Blindness; Bufonidae; Cell Nucleus; Darkness; Leydig Cells; Male; Melatonin; Spermatogenesi

1983
Effects of light on human melatonin production and the human circadian system.
    Progress in neuro-psychopharmacology & biological psychiatry, 1983, Volume: 7, Issue:4-6

    Topics: Animals; Bipolar Disorder; Blindness; Circadian Rhythm; Humans; Light; Melatonin; Rats; Seasons

1983
Coincidence of counter-antigonadal and counter-antithyroid action of melatonin administration via the drinking water in male golden hamsters.
    Life sciences, 1984, Feb-13, Volume: 34, Issue:7

    Topics: Animals; Blindness; Cricetinae; Dose-Response Relationship, Drug; Drinking; Male; Melatonin; Mesocri

1984
Different types of melatonin circadian secretory rhythms in some blind subjects.
    The Journal of clinical endocrinology and metabolism, 1983, Volume: 56, Issue:6

    Topics: Adult; Blindness; Circadian Rhythm; Female; Humans; Light; Longitudinal Studies; Male; Melatonin; Mi

1983
Ontogeny of the gonadal response of golden hamsters to short photoperiod, blinding, and melatonin.
    Biology of reproduction, 1982, Volume: 27, Issue:4

    Topics: Aging; Animals; Blindness; Cricetinae; Estrus; Female; Gonads; Light; Male; Melatonin; Mesocricetus;

1982
Effects of blinding or afternoon melatonin injections on plasma cholesterol, triglycerides, glucose, TSH and thyroid hormone levels in male and female Syrian hamsters.
    Progress in clinical and biological research, 1982, Volume: 92

    Topics: Animals; Blindness; Blood Glucose; Cholesterol; Cricetinae; Female; Male; Melatonin; Mesocricetus; P

1982
Thyroid hormones in male hamsters with activated pineals or melatonin treatment.
    Progress in clinical and biological research, 1982, Volume: 92

    Topics: Animals; Blindness; Cricetinae; Environment, Controlled; Genitalia, Male; Light; Male; Melatonin; Me

1982
Influence of subcutaneous deposits of melatonin on the antigonadotrophic effects of blinding and anosmia in male rats. A dose-response study.
    Neuroendocrinology, 1980, Volume: 30, Issue:3

    Topics: Animals; Blindness; Dose-Response Relationship, Drug; Drug Implants; Hormones; Luteinizing Hormone;

1980
Surgical removal of the olfactory bulbs increases sensitivity of the reproductive system of female rats to the inhibitory effects of late afternoon melatonin injections.
    The Journal of experimental zoology, 1980, Volume: 212, Issue:1

    Topics: Animals; Blindness; Body Weight; Darkness; Drug Administration Schedule; Female; Gonadotropins, Pitu

1980
Day-time naps and melatonin in blind people.
    Lancet (London, England), 1995, Dec-02, Volume: 346, Issue:8988

    Topics: Blindness; Circadian Rhythm; Humans; Melatonin; Sleep Wake Disorders

1995
[Melatonin treatment for sleep-wake disorder--an experience for a severely mental retarded patient with blindness].
    No to hattatsu = Brain and development, 1995, Volume: 27, Issue:5

    Topics: Administration, Oral; Blindness; Child; Circadian Rhythm; Humans; Intellectual Disability; Male; Mel

1995
Melatonin treatment of a non-24-hour sleep-wake cycle in a blind retarded child.
    Biological psychiatry, 1995, Jul-15, Volume: 38, Issue:2

    Topics: Blindness; Child, Preschool; Chromosomes, Human, Pair 22; Circadian Rhythm; Dose-Response Relationsh

1995
Vision without sight.
    The New England journal of medicine, 1995, Jan-05, Volume: 332, Issue:1

    Topics: Animals; Blindness; Circadian Rhythm; Humans; Melatonin; Vision, Ocular; Visual Perception

1995
Human circadian rhythms: lessons from the blind.
    Annals of medicine, 1993, Volume: 25, Issue:4

    Topics: Animals; Biological Clocks; Blindness; Circadian Rhythm; Humans; Light; Melatonin; Sleep

1993
Circadian sleep regulation in the absence of light perception: chronic non-24-hour circadian rhythm sleep disorder in a blind man with a regular 24-hour sleep-wake schedule.
    Sleep, 1993, Volume: 16, Issue:4

    Topics: Blindness; Body Temperature; Circadian Rhythm; Humans; Hydrocortisone; Light; Male; Melatonin; Middl

1993
Melatonin and the pituitary-thyroid axis status in blind adults: a possible resetting after puberty.
    Clinical endocrinology, 1995, Volume: 43, Issue:6

    Topics: Adolescent; Adult; Blindness; Female; Humans; Male; Melatonin; Pituitary Gland; Puberty; Thyroid Gla

1995
Persistence of circadian oscillation while locomotor activity and plasma melatonin levels became aperiodic under prolonged continuous light in the rat.
    Neuroscience letters, 1996, Sep-20, Volume: 216, Issue:1

    Topics: Animals; Blindness; Circadian Rhythm; Estrus; Eye Enucleation; Female; Melatonin; Motor Activity; Ph

1996
Relationship between melatonin rhythms and visual loss in the blind.
    The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:11

    Topics: Adult; Aged; Blindness; Circadian Rhythm; Female; Humans; Light; Male; Melatonin; Middle Aged; Sleep

1997
Relationship between melatonin rhythms and visual loss in the blind.
    The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:11

    Topics: Adult; Aged; Blindness; Circadian Rhythm; Female; Humans; Light; Male; Melatonin; Middle Aged; Sleep

1997
Relationship between melatonin rhythms and visual loss in the blind.
    The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:11

    Topics: Adult; Aged; Blindness; Circadian Rhythm; Female; Humans; Light; Male; Melatonin; Middle Aged; Sleep

1997
Relationship between melatonin rhythms and visual loss in the blind.
    The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:11

    Topics: Adult; Aged; Blindness; Circadian Rhythm; Female; Humans; Light; Male; Melatonin; Middle Aged; Sleep

1997
Nonphotic entrainment of the human circadian pacemaker.
    The American journal of physiology, 1998, Volume: 274, Issue:4 Pt 2

    Topics: Adult; Aged; Blindness; Body Temperature; Circadian Rhythm; Female; Humans; Male; Melatonin; Middle

1998
Reduced cancer incidence among the blind.
    Epidemiology (Cambridge, Mass.), 1998, Volume: 9, Issue:5

    Topics: Aged; Blindness; Breast Neoplasms; Cohort Studies; Female; Humans; Incidence; Male; Melatonin; Middl

1998
Pineal rhythms are synchronized to light-dark cycles in congenitally anophthalmic mutant rats.
    Brain research, 1999, Apr-17, Volume: 825, Issue:1-2

    Topics: Animals; Blindness; Circadian Rhythm; Darkness; Eye Enucleation; Lighting; Male; Melatonin; Motor Ac

1999
Sleep and activity rhythms are related to circadian phase in the blind.
    Sleep, 1999, Aug-01, Volume: 22, Issue:5

    Topics: Adult; Aged; Blindness; Circadian Rhythm; Female; Fourier Analysis; Homeostasis; Humans; Male; Melat

1999
Correlation between urinary cortisol and 6-sulphatoxymelatonin rhythms in field studies of blind subjects.
    Clinical endocrinology, 1999, Volume: 50, Issue:6

    Topics: Adult; Aged; Biomarkers; Blindness; Circadian Rhythm; Female; Humans; Hydrocortisone; Male; Melatoni

1999
Melatonin counteracts the stimulatory effects of blinding or exposure to red light on reproduction in the skipper frog Rana cyanophlyctis.
    General and comparative endocrinology, 2000, Volume: 118, Issue:1

    Topics: Animals; Blindness; Darkness; Female; Kinetics; Melatonin; Organ Size; Ovarian Follicle; Ovary; Ovid

2000
Melatonin, circadian rhythms, and sleep.
    The New England journal of medicine, 2000, Oct-12, Volume: 343, Issue:15

    Topics: Blindness; Circadian Rhythm; Dyssomnias; Humans; Melatonin; Sleep

2000
Effects of aging on the intrinsic circadian period of totally blind humans.
    Journal of biological rhythms, 2001, Volume: 16, Issue:1

    Topics: Adult; Aging; Blindness; Circadian Rhythm; Humans; Male; Melatonin; Middle Aged; Regression Analysis

2001
Absence of an increase in the duration of the circadian melatonin secretory episode in totally blind human subjects.
    The Journal of clinical endocrinology and metabolism, 2001, Volume: 86, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blindness; Circadian Rhythm; Female; Humans; Male; Melat

2001
Capturing the circadian rhythms of free-running blind people with 0.5 mg melatonin.
    Brain research, 2001, Nov-09, Volume: 918, Issue:1-2

    Topics: Adult; Biological Clocks; Blindness; Circadian Rhythm; Dose-Response Relationship, Drug; Drug Admini

2001
Capturing the circadian rhythms of free-running blind people with 0.5 mg melatonin.
    Brain research, 2001, Nov-09, Volume: 918, Issue:1-2

    Topics: Adult; Biological Clocks; Blindness; Circadian Rhythm; Dose-Response Relationship, Drug; Drug Admini

2001
Capturing the circadian rhythms of free-running blind people with 0.5 mg melatonin.
    Brain research, 2001, Nov-09, Volume: 918, Issue:1-2

    Topics: Adult; Biological Clocks; Blindness; Circadian Rhythm; Dose-Response Relationship, Drug; Drug Admini

2001
Capturing the circadian rhythms of free-running blind people with 0.5 mg melatonin.
    Brain research, 2001, Nov-09, Volume: 918, Issue:1-2

    Topics: Adult; Biological Clocks; Blindness; Circadian Rhythm; Dose-Response Relationship, Drug; Drug Admini

2001
Low, but not high, doses of melatonin entrained a free-running blind person with a long circadian period.
    Chronobiology international, 2002, Volume: 19, Issue:3

    Topics: Administration, Oral; Blindness; Circadian Rhythm; Dose-Response Relationship, Drug; Humans; Male; M

2002
[Melatonin treatment of a blind child with serious sleep disorders].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2002, Apr-20, Volume: 122, Issue:10

    Topics: Blindness; Child, Preschool; Chronic Disease; Developmental Disabilities; Humans; Male; Melatonin; P

2002
Blinding and pinealectomy in male hamsters: Effects of pineal indoles and P-chlorophenylalanine on testes, seminal vesicles, pituitary and adrenal glands.
    Acta endocrinologica, 1977, Volume: 84, Issue:2

    Topics: Animals; Blindness; Cricetinae; Fenclonine; Hydralazine; Indoles; Male; Melatonin; Organ Size; Pinea

1977
Effects of the pineal and melatonin on thyroid activity of male golden hamsters.
    General and comparative endocrinology, 1979, Volume: 38, Issue:2

    Topics: Animals; Blindness; Castration; Cricetinae; Male; Melatonin; Mesocricetus; Ocular Physiological Phen

1979
Hyperactivity in the blind-anosmic female rat: role of the pineal gland.
    Physiology & behavior, 1977, Volume: 18, Issue:2

    Topics: Animals; Blindness; Female; Humans; Hyperkinesis; Melatonin; Motor Activity; Olfaction Disorders; Pi

1977
Effects of neutralization of circulating melatonin and N-acetylserotonin on plasma prolactin levels.
    Neuroendocrinology, 1977, Volume: 23, Issue:1

    Topics: Animals; Antigens; Blindness; Circadian Rhythm; Environment; Lighting; Male; Melatonin; Pineal Gland

1977
A basic experimental approach in perspective of pineal and melatonin involvement in photoperiod-induced alteration of spermatogenesis in toad (Bufo melanostictus).
    Endokrinologie, 1978, Volume: 71, Issue:2

    Topics: Animals; Blindness; Bufonidae; Darkness; Leydig Cells; Light; Male; Melatonin; Pineal Gland; Spermat

1978
Differences in biological function between the blind and the sighted.
    Developmental medicine and child neurology, 1978, Volume: 20, Issue:5

    Topics: Blindness; Circadian Rhythm; Humans; Melatonin; Pineal Gland

1978
Some aspects of colour-change mechanism in the Indian fresh-water siluroid, Heteropneustes fossilis (Bloch).
    Biochemistry and experimental biology, 1978, Volume: 14, Issue:4

    Topics: Adaptation, Physiological; Animals; Blindness; Female; Fishes; Laminectomy; Light; Male; Melanophore

1978
Pineal function in hamsters bearing melatonin antibodies.
    Life sciences, 1976, Oct-15, Volume: 19, Issue:8

    Topics: Animals; Antigen-Antibody Reactions; Blindness; Gonadotropin-Releasing Hormone; Guinea Pigs; Hypotha

1976
Endocrine effects of the pineal gland and neutralization of circulating melatonin and N-acetylserotonin.
    Canadian journal of physiology and pharmacology, 1977, Volume: 55, Issue:3

    Topics: Adrenal Cortex; Adrenal Glands; Animals; Blindness; Corticosterone; Darkness; Growth; Male; Melatoni

1977
Free thyroxin index in normal, melatonin-treated and blind hamsters.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1977, Volume: 9, Issue:3

    Topics: Animals; Blindness; Cricetinae; Female; Male; Melatonin; Pineal Gland; Sex Factors; Thyroid Gland; T

1977
Antigonadal effects of blinding in the presence of antibody against circulating melatonin.
    Life sciences, 1977, Sep-01, Volume: 21, Issue:5

    Topics: Animals; Antigen-Antibody Reactions; Blindness; Body Weight; Genitalia, Male; Luteinizing Hormone; M

1977
Influence of melatonin, constant light, or blinding on reproductive system of gerbils (Meriones unguiculatus).
    Experientia, 1976, Oct-15, Volume: 32, Issue:10

    Topics: Animals; Blindness; Body Weight; Female; Genitalia; Gerbillinae; Light; Litter Size; Male; Melatonin

1976
Melatonin-pineal relationships in female golden hamsters.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1975, Volume: 149, Issue:1

    Topics: Animals; Blindness; Body Weight; Cricetinae; Dogs; Female; Luteinizing Hormone; Melatonin; Organ Siz

1975
A study of indoles which inhibit pineal antigonadotrophic activity in male hamsters.
    Endocrine research communications, 1975, Volume: 2, Issue:3

    Topics: Animals; Blindness; Cricetinae; Indoles; Luteinizing Hormone; Male; Melatonin; Pineal Gland; Pituita

1975
A counter antigonadotrophic effect of melatonin in male rats.
    Neuroendocrinology, 1975, Volume: 19, Issue:1

    Topics: Adrenal Glands; Animals; Blindness; Body Weight; Gonadotropins, Pituitary; Growth; Luteinizing Hormo

1975
Studies on the minimal dosage of melatonin required to inhibit pineal antigonadotrophic activity in male golden hamsters.
    Hormone research, 1975, Volume: 6, Issue:4

    Topics: Animals; Blindness; Cricetinae; Genitalia, Male; Gonadotropins; Luteinizing Hormone; Male; Melatonin

1975
Melatonin inhibition of pineal antigonadotrophic activity in male rats.
    Hormone research, 1975, Volume: 6, Issue:5-6

    Topics: Animals; Blindness; Body Weight; Genitalia, Male; Male; Melatonin; Organ Size; Pineal Gland; Pituita

1975
Regulation of pineal rhythms in chickens: effects of blinding, constant light, constant dark, and superior cervical ganglionectomy.
    Endocrinology, 1975, Volume: 97, Issue:6

    Topics: Acetylserotonin O-Methyltransferase; Acetyltransferases; Animals; Blindness; Chickens; Circadian Rhy

1975
[Interrelationship of the pineal body with the hypothalamo-hypophyseal complex. II. The effect of melatonin on the incorporation of H3-leucine in the anterior and medial hypothalamic nuclei of pinealectomized blinded rats].
    Problemy endokrinologii, 1976, Volume: 22, Issue:2

    Topics: Animals; Autoradiography; Blindness; Female; Hypothalamo-Hypophyseal System; Hypothalamus; Hypothala

1976
Melatonin and maternal factors shift the phase of NAT activity rhythm in the pineal gland in rat pups.
    Clinical neuropharmacology, 1992, Volume: 15 Suppl 1 Pt A

    Topics: Animals; Arylamine N-Acetyltransferase; Blindness; Female; Maternal Behavior; Melatonin; Periodicity

1992
The importance of timing in melatonin administration in a blind man.
    Journal of pineal research, 1992, Volume: 12, Issue:3

    Topics: Adolescent; Blindness; Circadian Rhythm; Drug Administration Schedule; Humans; Male; Melatonin; Slee

1992
Sleep propensity free-runs with the temperature, melatonin and cortisol rhythms in a totally blind person.
    Sleep, 1992, Volume: 15, Issue:4

    Topics: Adult; Blindness; Body Temperature; Circadian Rhythm; Humans; Hydrocortisone; Male; Melatonin; Sleep

1992
Circadian rhythm abnormalities in totally blind people: incidence and clinical significance.
    The Journal of clinical endocrinology and metabolism, 1992, Volume: 75, Issue:1

    Topics: Biological Clocks; Blindness; Circadian Rhythm; Humans; Hydrocortisone; Melatonin; Sleep

1992
Free-running melatonin, sleep propensity, cortisol and temperature rhythms in a totally blind person.
    The Japanese journal of psychiatry and neurology, 1992, Volume: 46, Issue:1

    Topics: Adult; Arousal; Blindness; Body Temperature Regulation; Circadian Rhythm; Humans; Hydrocortisone; Ma

1992
Feedback in the rabbit's central circadian system, revealed by the changes in its free-running food intake pattern induced by blinding, cervical sympathectomy, pinealectomy, and melatonin administration.
    Journal of biological rhythms, 1991,Fall, Volume: 6, Issue:3

    Topics: Animals; Blindness; Circadian Rhythm; Feedback; Feeding Behavior; Female; Ganglia, Sympathetic; Gang

1991
Circadian rhythms in 6-sulphatoxymelatonin and nocturnal sleep in blind children.
    Chronobiology international, 1991, Volume: 8, Issue:3

    Topics: Adolescent; Blindness; Child; Circadian Rhythm; Humans; Male; Melatonin; Sleep

1991
The role of arginine-vasopressin for pineal melatonin synthesis in the rat: involvement of vasopressinergic receptors.
    Neuroscience letters, 1991, Feb-11, Volume: 123, Issue:1

    Topics: Animals; Arginine Vasopressin; Arylamine N-Acetyltransferase; Blindness; Deamino Arginine Vasopressi

1991
Correction of non-24-hour sleep/wake cycle by melatonin in a blind retarded boy.
    Annals of neurology, 1991, Volume: 29, Issue:3

    Topics: Blindness; Child; Circadian Rhythm; Humans; Hydrocortisone; Intellectual Disability; Male; Melatonin

1991
Patterns of pineal melatonin secretion in rabbits: diurnal variation of basal and pulsatile release.
    Neuroendocrinology, 1990, Volume: 51, Issue:2

    Topics: Animals; Blindness; Circadian Rhythm; Darkness; Female; Light; Male; Melatonin; Pineal Gland; Rabbit

1990
Melatonin stabilises sleep onset time in a blind man without entrainment of cortisol or temperature rhythms.
    Neuroscience letters, 1990, May-31, Volume: 113, Issue:2

    Topics: Blindness; Body Temperature Regulation; Circadian Rhythm; Humans; Hydrocortisone; Male; Melatonin; M

1990
Inherited changes in concentrations of retinal and serum melatonin in the chicken.
    General and comparative endocrinology, 1989, Volume: 76, Issue:3

    Topics: Animals; Blindness; Body Weight; Chickens; Gas Chromatography-Mass Spectrometry; Heterozygote; Homoz

1989
Role of the pineal gland in the activity of nervous structures involved in sexual processes of the male rat.
    Comparative biochemistry and physiology. A, Comparative physiology, 1987, Volume: 88, Issue:1

    Topics: Animals; Blindness; Brain; Male; Melatonin; Orchiectomy; Organ Specificity; Oxygen Consumption; Pine

1987
Synchronisation of a disturbed sleep-wake cycle in a blind man by melatonin treatment.
    Lancet (London, England), 1988, Apr-02, Volume: 1, Issue:8588

    Topics: Blindness; Circadian Rhythm; Humans; Male; Melatonin; Middle Aged; Sleep Wake Disorders

1988
Melatonin inhibits metabolic activity in the rat suprachiasmatic nuclei.
    Neuroscience letters, 1987, Oct-16, Volume: 81, Issue:1-2

    Topics: Animals; Autoradiography; Biological Transport; Blindness; Carbon Radioisotopes; Deoxy Sugars; Deoxy

1987
The effect of melatonin administration and short exposures to cold on body temperature of the blind subterranean mole rat (Rodentia, Spalax ehrenberghi, Nehring).
    The Journal of experimental zoology, 1986, Volume: 238, Issue:1

    Topics: Animals; Blindness; Body Temperature; Body Temperature Regulation; Body Weight; Cold Temperature; Me

1986
Effects of pinealectomy and melatonin administration on thyroid follicles of blind Syrian hamsters.
    The Anatomical record, 1985, Volume: 211, Issue:1

    Topics: Animals; Blindness; Cricetinae; Male; Melatonin; Mesocricetus; Pineal Gland; Thyroid Gland; Thyrotro

1985
Pineal gland: evidence for an influence on ethanol preference in male Syrian hamsters.
    Comparative biochemistry and physiology. A, Comparative physiology, 1974, Volume: 47, Issue:1

    Topics: Alcohol Drinking; Animals; Blindness; Cricetinae; Darkness; Drinking; Ganglia, Autonomic; Light; Mal

1974
Retinal and pineal hydroxyindole-O-methyl transferases in the rat: changes following cervical sympathectomy, pinealectomy or blinding.
    Endocrinology, 1973, Volume: 92, Issue:5

    Topics: Animals; Blindness; Carbon Isotopes; Cervical Plexus; Circadian Rhythm; Male; Melatonin; Methyltrans

1973
Effect of the pineal gland on alcohol consumption by congenitally blind male rats.
    Quarterly journal of studies on alcohol, 1973, Volume: 34, Issue:3

    Topics: Alcohol Drinking; Animals; Blindness; Circadian Rhythm; Drinking; Drinking Behavior; Ethanol; Male;

1973
Relationship between the pineal gland, other endocrine glands and reproductive organs of single and parabiosed golden hamsters.
    Acta endocrinologica, 1973, Volume: 74, Issue:3

    Topics: Adrenal Glands; Animals; Blindness; Body Weight; Castration; Cricetinae; Female; Iodine Radioisotope

1973
The effects of light and sympathetic innervation to the head on nidation in mink.
    The Journal of experimental zoology, 1974, Volume: 187, Issue:2

    Topics: Animals; Blepharoptosis; Blindness; Embryo Implantation; Female; Ganglia, Autonomic; Genetic Linkage

1974
Pineal N-acetyltransferase activity in blinded and anosmic male rats.
    Endocrinology, 1971, Volume: 89, Issue:4

    Topics: Animals; Blindness; Carbon Isotopes; Circadian Rhythm; Male; Melatonin; Olfaction Disorders; Pineal

1971
A melatonin rhythm persists in rat pineals in darkness.
    Endocrinology, 1971, Volume: 89, Issue:6

    Topics: Animals; Blindness; Circadian Rhythm; Darkness; Locomotion; Male; Melatonin; Pineal Gland; Rats

1971
Effect of blinding on the excretion of a gonadotropin-inhibiting substance in male rats.
    Endocrinologia japonica, 1971, Volume: 18, Issue:6

    Topics: Animals; Blindness; Chorionic Gonadotropin; Female; Gonadotropins; Gonadotropins, Equine; Male; Mela

1971
Effect of biogenic amines on the endocrine axis and esterase activity of hamster testes.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1970, Volume: 135, Issue:1

    Topics: Adrenal Glands; Animals; Blindness; Cricetinae; Esterases; Light; Male; Melatonin; Microscopy, Elect

1970
Testicular steroidogeneis in vitro in the rat in response to blinding, pinealectomy and to the addition of melatonin.
    Steroids, 1971, Volume: 17, Issue:2

    Topics: Androgens; Androstanes; Animals; Blindness; Cholesterol; Depression, Chemical; Fructose; In Vitro Te

1971
Stimulation of hydroxyindole-o-methyl transferase activity in hamster pineal glands by blinding or continuous darkness.
    Endocrinology, 1968, Volume: 82, Issue:6

    Topics: Animals; Blindness; Cricetinae; Darkness; Light; Male; Melatonin; Organ Size; Pineal Gland; Radiatio

1968
Hydroxyindole-O-methyl-transferase activity: effect of sympathetic nerve stimulation.
    Science (New York, N.Y.), 1968, Oct-18, Volume: 162, Issue:3851

    Topics: Animals; Blindness; Circadian Rhythm; Electric Stimulation; Ganglia, Autonomic; Light; Male; Melaton

1968
Central control of the pineal gland: visual pathways.
    Archives of neurology, 1968, Volume: 18, Issue:2

    Topics: Animals; Blindness; Darkness; Environment; Estrus; Female; Light; Melatonin; Mesencephalon; Norepine

1968
The control of circadian pigment changes in the pencil fish: a proposed role for melatonin.
    Life sciences, 1968, Sep-15, Volume: 7, Issue:18

    Topics: Animals; Blindness; Circadian Rhythm; Darkness; Fishes; Light; Melatonin; Pigmentation

1968