Page last updated: 2024-10-19

melatonin and Bladder Cancer

melatonin has been researched along with Bladder Cancer in 9 studies

Research Excerpts

ExcerptRelevanceReference
"Melatonin has anticancer activity when administered alone or in combination with standard chemotherapeutic agents, with measurable improvements seen in the clinical endpoints of tumor regression and patient survival."5.72Melatonin Inhibits EMT in Bladder Cancer by Targeting Autophagy. ( Chao, CC; Chen, PC; Hsiao, SY; Lin, TH; Tang, CH, 2022)
"Melatonin treatment inhibited proliferation and migration and enhanced apoptosis of bladder cancer cells."5.62Melatonin reduces proliferation and promotes apoptosis of bladder cancer cells by suppressing O-GlcNAcylation of cyclin-dependent-like kinase 5. ( Gou, J; Guan, F; Jiang, Y; Li, H; Li, X; Liang, L; Lin, M; Ma, Q; Ning, L; Tan, Z; Wu, J, 2021)
"Melatonin is a well-known natural hormone, which shows a potential anticancer effect in many human cancers."1.91Melatonin inhibits bladder tumorigenesis by suppressing PPARγ/ENO1-mediated glycolysis. ( Deng, Z; Fang, Y; Ju, L; Liu, W; Qian, K; Shan, D; Shen, D; Wang, G; Wang, X; Xiao, Y; Yu, M; Zhang, Y; Zhou, F, 2023)
"The melatonin treatment significantly reduced T24 and UMUC3 bladder cancer cell proliferation and clonogenic ability."1.91Melatonin induces cell cycle arrest and suppresses tumor invasion in urinary bladder urothelial carcinoma. ( Chang, YC; Chen, SL; Dong, C; Hsieh, TY; Lee, TH; Lu, LY; Sung, WW; Yu, CY, 2023)
"Melatonin has anticancer activity when administered alone or in combination with standard chemotherapeutic agents, with measurable improvements seen in the clinical endpoints of tumor regression and patient survival."1.72Melatonin Inhibits EMT in Bladder Cancer by Targeting Autophagy. ( Chao, CC; Chen, PC; Hsiao, SY; Lin, TH; Tang, CH, 2022)
"Melatonin treatment inhibited proliferation and migration and enhanced apoptosis of bladder cancer cells."1.62Melatonin reduces proliferation and promotes apoptosis of bladder cancer cells by suppressing O-GlcNAcylation of cyclin-dependent-like kinase 5. ( Gou, J; Guan, F; Jiang, Y; Li, H; Li, X; Liang, L; Lin, M; Ma, Q; Ning, L; Tan, Z; Wu, J, 2021)
"Melatonin is a hormone secreted from pineal glands of mammals and possesses diverse physiological functions."1.46Melatonin potentiates the antitumor effect of curcumin by inhibiting IKKβ/NF-κB/COX-2 signaling pathway. ( Du, X; Hou, Q; Jiang, J; Liu, F; Peng, Y; Shrestha, S; Song, J; Song, X; Sun, D; Sun, X; Wang, Q; Xing, J; Zhao, J; Zhu, J, 2017)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (33.33)24.3611
2020's6 (66.67)2.80

Authors

AuthorsStudies
Wu, J1
Tan, Z1
Li, H1
Lin, M1
Jiang, Y1
Liang, L1
Ma, Q1
Gou, J1
Ning, L1
Li, X2
Guan, F1
Miyake, M1
Nishimura, N1
Ohnishi, S1
Oda, Y1
Miyamoto, T1
Shimizu, T1
Hori, S1
Morizawa, Y1
Gotoh, D1
Nakai, Y1
Anai, S1
Torimoto, K1
Aoki, K1
Fujii, T1
Tanaka, N1
Fujimoto, K1
Hsiao, SY1
Tang, CH1
Chen, PC1
Lin, TH1
Chao, CC1
Shen, D1
Deng, Z1
Liu, W1
Zhou, F1
Fang, Y1
Shan, D1
Wang, G1
Qian, K1
Yu, M1
Zhang, Y2
Ju, L1
Xiao, Y1
Wang, X1
Hsieh, TY1
Sung, WW1
Chang, YC1
Yu, CY1
Lu, LY1
Dong, C1
Lee, TH1
Chen, SL1
Lim, MA1
Pranata, R1
Jabłońska, J1
Kluska, M1
Lin, XJ1
Liu, R1
Li, C1
Yi, X1
Fu, B1
Walker, MJ1
Xu, XM1
Sun, G1
Lin, CH1
Lan, NSR1
Yeap, BB1
Fegan, PG1
Green, G1
Rankin, JM1
Dwivedi, G1
Habibi, A1
Karami, S1
Varmira, K1
Hadadi, M1
Zhang, M1
Li, Q1
Lan, X1
Wang, Z1
Zheng, J1
Eskandari-Sedighi, G1
Cortez, LM1
Yang, J1
Daude, N1
Shmeit, K1
Sim, V1
Westaway, D1
Weigand, S1
O'Connor, M1
Blažek, P1
Kantenwein, V1
Friedrich, L1
Grebmer, C1
Schaarschmidt, C1
von Olshausen, G1
Reents, T1
Deisenhofer, I1
Lennerz, C1
Kolb, C1
Iwata, H1
Sassa, N1
Kato, M1
Murase, Y1
Seko, S1
Kawanishi, H1
Hattori, R1
Gotoh, M1
Tsuzuki, T1
Chen, D1
Zhang, J1
Chen, YP1
Li, Y1
Zhou, M1
Waterhouse, GIN1
Sun, J1
Shi, W1
Ai, S1
Manne, ASN1
Hegde, AR1
Raut, SY1
Rao, RR1
Kulkarni, VI1
Mutalik, S1
Jafari, R1
Hectors, SJ1
Koehne de González, AK1
Spincemaille, P1
Prince, MR1
Brittenham, GM1
Wang, Y1
Shrestha, S1
Zhu, J1
Wang, Q1
Du, X1
Liu, F1
Jiang, J1
Song, J1
Xing, J1
Sun, D1
Hou, Q1
Peng, Y1
Zhao, J1
Sun, X1
Song, X1
Han, YS1
Kim, SM1
Lee, JH1
Jung, SK1
Noh, H1
Lee, SH1
Chen, YT1
Yang, CC1
Shao, PL1
Huang, CR1
Yip, HK1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Association of Anesthesia Technique With Morbidity and Mortality in Patients With COVID-19 and Surgery for Hip Fracture: a Retrospective Population Cohort Study[NCT05133648]1,000 participants (Anticipated)Observational2023-01-05Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

9 other studies available for melatonin and Bladder Cancer

ArticleYear
Melatonin reduces proliferation and promotes apoptosis of bladder cancer cells by suppressing O-GlcNAcylation of cyclin-dependent-like kinase 5.
    Journal of pineal research, 2021, Volume: 71, Issue:3

    Topics: Apoptosis; Cell Proliferation; Cyclins; Humans; Melatonin; N-Acetylglucosaminyltransferases; Proteom

2021
Association between urine 6-sulfatoxy-melatonin level and intravesical Bacillus Calmette-Guerin treatment-induced sleep quality deterioration in patients with non-muscle invasive bladder cancer.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022, Volume: 30, Issue:7

    Topics: Administration, Intravesical; BCG Vaccine; Creatinine; Humans; Male; Melatonin; Neoplasm Invasivenes

2022
Melatonin Inhibits EMT in Bladder Cancer by Targeting Autophagy.
    Molecules (Basel, Switzerland), 2022, Dec-07, Volume: 27, Issue:24

    Topics: Animals; Autophagy; Cell Line, Tumor; Epithelial-Mesenchymal Transition; Melatonin; Mice; Signal Tra

2022
Melatonin inhibits bladder tumorigenesis by suppressing PPARγ/ENO1-mediated glycolysis.
    Cell death & disease, 2023, 04-06, Volume: 14, Issue:4

    Topics: Biomarkers, Tumor; Cell Transformation, Neoplastic; DNA-Binding Proteins; Glycolysis; Humans; Melato

2023
Melatonin induces cell cycle arrest and suppresses tumor invasion in urinary bladder urothelial carcinoma.
    Aging, 2023, 04-21, Volume: 15, Issue:8

    Topics: Apoptosis; Carcinoma, Transitional Cell; Cell Cycle; Cell Cycle Checkpoints; Cell Line, Tumor; Cell

2023
    Journal of clinical orthopaedics and trauma, 2021, Volume: 12, Issue:1

    Topics: Acute Coronary Syndrome; Adolescent; Adsorption; Adult; Aged; Animals; Aspergillus; Aspergillus oryz

2021
Melatonin potentiates the antitumor effect of curcumin by inhibiting IKKβ/NF-κB/COX-2 signaling pathway.
    International journal of oncology, 2017, Volume: 51, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle Checkpoints; Cell Line, Tumor; C

2017
Melatonin protects chronic kidney disease mesenchymal stem cells against senescence via PrP
    Journal of pineal research, 2019, Volume: 66, Issue:1

    Topics: Animals; Blotting, Western; Cell Line, Tumor; Cell Survival; Cellular Senescence; Humans; Immunohist

2019
Melatonin-mediated downregulation of ZNF746 suppresses bladder tumorigenesis mainly through inhibiting the AKT-MMP-9 signaling pathway.
    Journal of pineal research, 2019, Volume: 66, Issue:1

    Topics: Animals; Male; Matrix Metalloproteinase 9; Melatonin; Mice; Mice, Inbred C57BL; Proto-Oncogene Prote

2019