melatonin has been researched along with B16 Melanoma in 15 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Melanoma is the most aggressive type of skin cancer, with a greater risk of metastasis and a higher prevalence and mortality rate." | 3.01 | Melatonin as a Repurposed Drug for Melanoma Treatment. ( Pathipaka, R; Sahu, RP; Thyagarajan, A, 2023) |
| "Melatonin has oncostatic effects on several types of cancer (breast, prostate, and colorectal cancers), while it can be self-defeating in others, such as lymphoma." | 1.35 | Effects of exogenous melatonin and circadian synchronization on tumor progression in melanoma-bearing C57BL6 mice. ( Alvarez, N; Madrid, JA; Otálora, BB; Rol, MA; Vicente, V, 2008) |
| "Melatonin has been reported to possess growth inhibitory action at certain physiological doses in cancer cell lines in vitro and oncostatic action under in vivo conditions." | 1.32 | Pharmacological action of high doses of melatonin on B16 murine melanoma cells depends on cell number at time of exposure. ( Jayaraman, S; Yerneni, LK, 2003) |
| "Melatonin can enhance and suppress constitutive protein secretion from murine melanoma M2R cells in vitro in a cholera-toxin (CTX) sensitive process." | 1.30 | Involvement of cGMP in cellular melatonin responses. ( Bubis, M; Zisapel, N, 1999) |
| "Melatonin was found to have a small inhibitory effect on tyrosinase activity and a slight stimulatory action on dopachrome tautomerase activity in B16 mouse melanoma cells." | 1.29 | Melatonin antagonizes alpha-melanocyte-stimulating hormone enhancement of melanogenesis in mouse melanoma cells by blocking the hormone-induced accumulation of the c locus tyrosinase. ( Benedito, E; García-Borrón, JC; Lozano, JA; Oaknin, S; Solano, F; Valverde, P, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (60.00) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 3 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pathipaka, R | 1 |
| Thyagarajan, A | 1 |
| Sahu, RP | 1 |
| Alvarez-Artime, A | 1 |
| Cernuda-Cernuda, R | 1 |
| Cepas, V | 1 |
| Gonzalez-Menendez, P | 1 |
| Fernadez-Vega, S | 1 |
| Quiros-Gonzalez, I | 1 |
| Sainz, RM | 1 |
| Mayo, JC | 1 |
| Perdomo, J | 1 |
| Quintana, C | 1 |
| González, I | 1 |
| Hernández, I | 1 |
| Rubio, S | 1 |
| Loro, JF | 1 |
| Reiter, RJ | 1 |
| Estévez, F | 1 |
| Quintana, J | 1 |
| Yerneni, LK | 1 |
| Jayaraman, S | 1 |
| Otálora, BB | 1 |
| Madrid, JA | 1 |
| Alvarez, N | 1 |
| Vicente, V | 1 |
| Rol, MA | 1 |
| Bubis, M | 3 |
| Zisapel, N | 3 |
| Valverde, P | 1 |
| Benedito, E | 1 |
| Solano, F | 1 |
| Oaknin, S | 1 |
| Lozano, JA | 1 |
| García-Borrón, JC | 1 |
| Mengeaud, V | 1 |
| Skene, D | 1 |
| Pevet, P | 1 |
| Ortonne, JP | 1 |
| Helton, RA | 1 |
| Harrison, WA | 1 |
| Kelley, K | 1 |
| Kane, MA | 1 |
| Eison, AS | 1 |
| Mullins, UL | 1 |
| Slominski, A | 1 |
| Pruski, D | 1 |
| Anis, Y | 1 |
| Cos, S | 1 |
| Garcia-Bolado, A | 1 |
| Sánchez-Barceló, EJ | 1 |
| Pickering, DS | 1 |
| Niles, LP | 1 |
1 review available for melatonin and B16 Melanoma
| Article | Year |
|---|---|
Melatonin as a Repurposed Drug for Melanoma Treatment.
Topics: Animals; Melanoma, Experimental; Melatonin; Pineal Gland; Signal Transduction; Skin Neoplasms | 2023 |
14 other studies available for melatonin and B16 Melanoma
| Article | Year |
|---|---|
Melatonin-Induced Cytoskeleton Reorganization Leads to Inhibition of Melanoma Cancer Cell Proliferation.
Topics: Actins; Animals; Antioxidants; Catalase; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cytosk | 2020 |
Melatonin Induces Melanogenesis in Human SK-MEL-1 Melanoma Cells Involving Glycogen Synthase Kinase-3 and Reactive Oxygen Species.
Topics: Antioxidants; Cell Line, Tumor; Glutathione; Glycogen Synthase Kinase 3; Humans; Melanins; Melanoma, | 2020 |
Pharmacological action of high doses of melatonin on B16 murine melanoma cells depends on cell number at time of exposure.
Topics: Animals; Antineoplastic Agents; Antioxidants; Cell Division; Culture Media; Dose-Response Relationsh | 2003 |
Effects of exogenous melatonin and circadian synchronization on tumor progression in melanoma-bearing C57BL6 mice.
Topics: Animals; Body Temperature; Circadian Rhythm; Disease Progression; Light; Male; Melanoma, Experimenta | 2008 |
Modulation by melatonin of protein secretion from melanoma cells: is cAMP involved?
Topics: Animals; Bucladesine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors | 1995 |
Melatonin antagonizes alpha-melanocyte-stimulating hormone enhancement of melanogenesis in mouse melanoma cells by blocking the hormone-induced accumulation of the c locus tyrosinase.
Topics: alpha-MSH; Animals; Enzyme Repression; Melanins; Melanoma, Experimental; Melatonin; Mice; Monophenol | 1995 |
No high affinity melatonin binding sites are detected in murine melanoma cells and in normal human melanocytes cultured in vitro.
Topics: Animals; Binding Sites; Chickens; Humans; Iodine Radioisotopes; Kinetics; Melanoma, Experimental; Me | 1994 |
Melatonin interactions with cultured murine B16 melanoma cells.
Topics: Animals; Biological Transport; Cell Division; Estradiol; Humans; Melanoma; Melanoma, Experimental; M | 1993 |
Melatonin binding sites are functionally coupled to phosphoinositide hydrolysis in Syrian hamster RPMI 1846 melanoma cells.
Topics: Animals; Cricetinae; Hydrolysis; Melanoma, Experimental; Melatonin; Mesocricetus; Phosphatidylinosit | 1993 |
Melatonin inhibits proliferation and melanogenesis in rodent melanoma cells.
Topics: 5-Methoxytryptamine; Animals; Cell Division; DNA Replication; DNA, Neoplasm; Dose-Response Relations | 1993 |
Enhancement by melatonin of GTP exchange and ADP ribosylation reactions.
Topics: Adenosine Diphosphate; Animals; Cholera Toxin; Guanosine Triphosphate; Melanoma, Experimental; Melat | 1996 |
Involvement of cGMP in cellular melatonin responses.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Cholera Toxin; Cyclic GMP; Dibutyryl Cyclic GMP; GTP-B | 1999 |
Direct antiproliferative effects of melatonin on two metastatic cell sublines of mouse melanoma (B16BL6 and PG19).
Topics: Animals; Coloring Agents; Dose-Response Relationship, Drug; Humans; Melanoma, Experimental; Melatoni | 2001 |
Expression of nanomolar-affinity binding sites for melatonin in Syrian hamster RPMI 1846 melanoma cells.
Topics: Adenylyl Cyclases; Animals; Binding Sites; Cricetinae; Culture Media; Cyclic AMP; Melanoma, Experime | 1992 |