melatonin has been researched along with Autoimmune Disease in 26 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " Melatonin has shown beneficial activity in several animal models and clinical trials of inflammatory autoimmune diseases, but the role of melatonin is controversial in RA." | 9.05 | Reconsidering the Role of Melatonin in Rheumatoid Arthritis. ( Huang, CC; Liu, SC; MacDonald, IJ; Tang, CH, 2020) |
| "Melatonin regulates autoimmune T cells by restraining effector T cells and facilitating Treg generation, indicating that melatonin could be a hopeful treatment alternative for autoimmune uveitis." | 8.12 | Melatonin, an endogenous hormone, modulates Th17 cells via the reactive-oxygen species/TXNIP/HIF-1α axis to alleviate autoimmune uveitis. ( Chen, G; Chen, Q; Chen, X; Chen, Y; Hu, Y; Huang, H; Huang, J; Li, Z; Liang, D; Su, W; Xie, Y; Zhu, W, 2022) |
| "Autoimmune diseases are a broad spectrum of disorders involved in the imbalance of T-cell subsets, in which interplay or interaction of Th1, Th17 and Tregs are most important, resulting in prolonged inflammation and subsequent tissue damage." | 6.61 | Potential role of melatonin in autoimmune diseases. ( Dan, YL; Davis, C; Hu, W; Li, XM; Mao, YM; Pan, HF; Wang, DG; Wang, P; Wu, Q; Zhao, CN, 2019) |
| "Melatonin therapy has been investigated in several animal models of autoimmune disease, where it has a beneficial effect in a number of models excepting rheumatoid arthritis, and has been evaluated in clinical autoimmune diseases including rheumatoid arthritis and ulcerative colitis." | 6.49 | Modulation by melatonin of the pathogenesis of inflammatory autoimmune diseases. ( Chang, DM; Chen, SJ; Huang, SH; Lin, GJ; Sytwu, HK; Wang, CH, 2013) |
| "Melatonin is a neuroendocrine hormone mainly secreted by the pineal gland that plays an important role in the maintenance of the circadian rhythm and immunomodulation." | 5.72 | Melatonin regulates the immune response and improves Sjögren's syndrome-like symptoms in NOD/Ltj Mice. ( Cheng, B; Ding, Y; Liu, Y; Wei, M; Weng, X; Yu, S, 2022) |
| "Multiple sclerosis is a central nervous system demyelinating disease." | 5.29 | Melanin, melatonin, melanocyte-stimulating hormone, and the susceptibility to autoimmune demyelination: a rationale for light therapy in multiple sclerosis. ( Constantinescu, CS, 1995) |
| " Melatonin has shown beneficial activity in several animal models and clinical trials of inflammatory autoimmune diseases, but the role of melatonin is controversial in RA." | 5.05 | Reconsidering the Role of Melatonin in Rheumatoid Arthritis. ( Huang, CC; Liu, SC; MacDonald, IJ; Tang, CH, 2020) |
| "Melatonin regulates autoimmune T cells by restraining effector T cells and facilitating Treg generation, indicating that melatonin could be a hopeful treatment alternative for autoimmune uveitis." | 4.12 | Melatonin, an endogenous hormone, modulates Th17 cells via the reactive-oxygen species/TXNIP/HIF-1α axis to alleviate autoimmune uveitis. ( Chen, G; Chen, Q; Chen, X; Chen, Y; Hu, Y; Huang, H; Huang, J; Li, Z; Liang, D; Su, W; Xie, Y; Zhu, W, 2022) |
| "Melatonin therapy has been investigated in several animal models of autoimmune disease, where it has a beneficial effect in a number of models excepting rheumatoid arthritis, and has been evaluated in clinical autoimmune diseases including rheumatoid arthritis and ulcerative colitis." | 2.49 | Modulation by melatonin of the pathogenesis of inflammatory autoimmune diseases. ( Chang, DM; Chen, SJ; Huang, SH; Lin, GJ; Sytwu, HK; Wang, CH, 2013) |
| "Melatonin is a neuroendocrine hormone mainly secreted by the pineal gland that plays an important role in the maintenance of the circadian rhythm and immunomodulation." | 1.72 | Melatonin regulates the immune response and improves Sjögren's syndrome-like symptoms in NOD/Ltj Mice. ( Cheng, B; Ding, Y; Liu, Y; Wei, M; Weng, X; Yu, S, 2022) |
| "Rat adjuvant arthritis is a chronic T cell-dependent autoimmune disease with many similarities to rheumatoid arthritis." | 1.29 | Thiazolidine diones, specific ligands of the nuclear receptor retinoid Z receptor/retinoid acid receptor-related orphan receptor alpha with potent antiarthritic activity. ( Carlberg, C; Jagher, B; Missbach, M; Nayeri, S; Sigg, I; Wiesenberg, I, 1996) |
| "Multiple sclerosis is a central nervous system demyelinating disease." | 1.29 | Melanin, melatonin, melanocyte-stimulating hormone, and the susceptibility to autoimmune demyelination: a rationale for light therapy in multiple sclerosis. ( Constantinescu, CS, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.85) | 18.7374 |
| 1990's | 7 (26.92) | 18.2507 |
| 2000's | 4 (15.38) | 29.6817 |
| 2010's | 8 (30.77) | 24.3611 |
| 2020's | 6 (23.08) | 2.80 |
| Authors | Studies |
|---|---|
| Nikolaev, G | 1 |
| Robeva, R | 1 |
| Konakchieva, R | 1 |
| Liu, Y | 2 |
| Weng, X | 1 |
| Wei, M | 1 |
| Yu, S | 1 |
| Ding, Y | 1 |
| Cheng, B | 1 |
| Huang, J | 1 |
| Li, Z | 2 |
| Hu, Y | 1 |
| Xie, Y | 1 |
| Huang, H | 1 |
| Chen, Q | 1 |
| Chen, G | 1 |
| Zhu, W | 1 |
| Chen, Y | 1 |
| Su, W | 1 |
| Chen, X | 1 |
| Liang, D | 1 |
| Tan, YQ | 1 |
| Zhou, G | 1 |
| Benvenga, S | 1 |
| Feldt-Rasmussen, U | 1 |
| Bonofiglio, D | 1 |
| Asamoah, E | 1 |
| Reynolds, AC | 1 |
| Marshall, NS | 1 |
| Hill, CL | 1 |
| Adams, RJ | 1 |
| MacDonald, IJ | 1 |
| Huang, CC | 1 |
| Liu, SC | 1 |
| Tang, CH | 1 |
| Zhao, CN | 1 |
| Wang, P | 1 |
| Mao, YM | 1 |
| Dan, YL | 1 |
| Wu, Q | 1 |
| Li, XM | 1 |
| Wang, DG | 1 |
| Davis, C | 1 |
| Hu, W | 1 |
| Pan, HF | 1 |
| Lin, GJ | 1 |
| Huang, SH | 1 |
| Chen, SJ | 1 |
| Wang, CH | 1 |
| Chang, DM | 1 |
| Sytwu, HK | 1 |
| Kuklina, EM | 1 |
| Arushanian, EB | 1 |
| Csaba, G | 1 |
| D'Angelo, G | 1 |
| Marseglia, L | 1 |
| Manti, S | 1 |
| Colavita, L | 1 |
| Cuppari, C | 1 |
| Impellizzeri, P | 1 |
| Arena, S | 1 |
| Arrigo, T | 1 |
| Salpietro, C | 1 |
| Gitto, E | 1 |
| Escames, G | 1 |
| López, LC | 1 |
| García, JA | 1 |
| García-Corzo, L | 1 |
| Ortiz, F | 1 |
| Acuña-Castroviejo, D | 1 |
| Maestroni, GJ | 4 |
| Sulli, A | 2 |
| Pizzorni, C | 2 |
| Villaggio, B | 2 |
| Cutolo, M | 2 |
| Hertens, E | 1 |
| Craviotto, C | 1 |
| Briata, M | 1 |
| Seriolo, B | 1 |
| Carrillo-Vico, A | 1 |
| Reiter, RJ | 1 |
| Lardone, PJ | 1 |
| Herrera, JL | 1 |
| Fernández-Montesinos, R | 1 |
| Guerrero, JM | 2 |
| Pozo, D | 1 |
| Koshevenko, IuN | 1 |
| Frolov, EP | 1 |
| Mattsson, R | 1 |
| Hannsson, I | 1 |
| Holmdahl, R | 1 |
| Missbach, M | 1 |
| Jagher, B | 1 |
| Sigg, I | 1 |
| Nayeri, S | 1 |
| Carlberg, C | 1 |
| Wiesenberg, I | 1 |
| Constantinescu, CS | 1 |
| Conti, A | 2 |
| Lopez-Gonzalez, MA | 1 |
| Sanchez, B | 1 |
| Delgado, F | 1 |
| López González, MA | 1 |
| Mata Maderuelo, F | 1 |
| Delgado Moreno, F | 1 |
| Sandyk, R | 1 |
15 reviews available for melatonin and Autoimmune Disease
| Article | Year |
|---|---|
Membrane Melatonin Receptors Activated Cell Signaling in Physiology and Disease.
Topics: Animals; Autoimmune Diseases; Diabetes Mellitus, Type 2; Humans; Melatonin; Neoplasms; Receptors, G- | 2021 |
Melatonin: a potential therapeutic approach for the management of primary Sjögren's syndrome.
Topics: Animals; Autoantibodies; Autoimmune Diseases; Melatonin; Salivary Glands; Sjogren's Syndrome | 2023 |
Nutraceutical Supplements in the Thyroid Setting: Health Benefits beyond Basic Nutrition.
Topics: Autoimmune Diseases; Carnitine; Diet; Dietary Supplements; Health Promotion; Humans; Inositol; Melat | 2019 |
Systematic review of the efficacy of commonly prescribed pharmacological treatments for primary treatment of sleep disturbance in patients with diagnosed autoimmune disease.
Topics: Autoimmune Diseases; Humans; Melatonin; Polysomnography; Quality of Life; Randomized Controlled Tria | 2020 |
Reconsidering the Role of Melatonin in Rheumatoid Arthritis.
Topics: Animals; Arthritis, Rheumatoid; Autoimmune Diseases; Circadian Clocks; Circadian Rhythm; Cytokines; | 2020 |
Potential role of melatonin in autoimmune diseases.
Topics: Animals; Autoimmune Diseases; Humans; Immunomodulation; Melatonin; Receptors, Melatonin | 2019 |
Modulation by melatonin of the pathogenesis of inflammatory autoimmune diseases.
Topics: Animals; Autoimmune Diseases; Clinical Trials as Topic; Disease Models, Animal; Humans; Inflammation | 2013 |
[MELATONIN TREATMENT OF AUTOIMMUNE AND ALLERGIC PATHOLOGY].
Topics: Animals; Autoimmune Diseases; Humans; Hypersensitivity; Melatonin; Pineal Gland | 2015 |
[The role of the pineal-thymus system in the regulation of autoimmunity, aging and lifespan].
Topics: Aging; Animals; Autoimmune Diseases; Autoimmunity; Circadian Rhythm; Hormones; Humans; Life Expectan | 2016 |
Atopy and autoimmune thyroid diseases: melatonin can be useful?
Topics: Antioxidants; Autoimmune Diseases; Child; Humans; Hypersensitivity; Melatonin; Thyroid Diseases | 2016 |
Mitochondrial DNA and inflammatory diseases.
Topics: Autoimmune Diseases; Carrier Proteins; DNA, Mitochondrial; Humans; Immunity, Innate; Inflammation; M | 2012 |
Melatonin in rheumatoid arthritis: synovial macrophages show melatonin receptors.
Topics: Adult; Aged; Arthritis, Rheumatoid; Autoimmune Diseases; Circadian Rhythm; Cytokines; Female; Humans | 2002 |
The modulatory role of melatonin on immune responsiveness.
Topics: Adjuvants, Immunologic; Animals; Autoimmune Diseases; B-Lymphocytes; Clinical Trials as Topic; Cytok | 2006 |
[Problems and prospects of vitiligo study].
Topics: Adrenal Cortex; Animals; Autoimmune Diseases; Biogenic Amines; Cyclic AMP; Female; Humans; Melanins; | 1981 |
Melatonin rhythms in mice: role in autoimmune and lymphoproliferative diseases.
Topics: Animals; Autoimmune Diseases; Lymphoproliferative Disorders; Melatonin; Mice; Periodicity; Pineal Gl | 1998 |
11 other studies available for melatonin and Autoimmune Disease
| Article | Year |
|---|---|
Melatonin regulates the immune response and improves Sjögren's syndrome-like symptoms in NOD/Ltj Mice.
Topics: Animals; Autoimmune Diseases; Disease Models, Animal; Humans; Immunity; Melatonin; Mice; Mice, Inbre | 2022 |
Melatonin, an endogenous hormone, modulates Th17 cells via the reactive-oxygen species/TXNIP/HIF-1α axis to alleviate autoimmune uveitis.
Topics: Animals; Autoimmune Diseases; Carrier Proteins; Melatonin; Mice; Oxygen; Reactive Oxygen Species; Th | 2022 |
Melatonin as potential inducer of Th17 cell differentiation.
Topics: Autoimmune Diseases; Cell Differentiation; Disease Progression; Female; Humans; Immune System; Inter | 2014 |
Melatonin serum levels in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Autoimmune Diseases; Circadian Rhythm; Cytokines; Edema; Female; | 2002 |
Pineal gland in autoimmunity: melatonin-dependent exaggeration of collagen-induced arthritis in mice.
Topics: Animals; Arthritis, Rheumatoid; Autoimmune Diseases; Autoimmunity; Bromocriptine; Collagen; Darkness | 1994 |
Thiazolidine diones, specific ligands of the nuclear receptor retinoid Z receptor/retinoid acid receptor-related orphan receptor alpha with potent antiarthritic activity.
Topics: Acetamides; Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Exp | 1996 |
Melanin, melatonin, melanocyte-stimulating hormone, and the susceptibility to autoimmune demyelination: a rationale for light therapy in multiple sclerosis.
Topics: Animals; Autoimmune Diseases; Demyelinating Diseases; Encephalomyelitis, Autoimmune, Experimental; H | 1995 |
Role of the pineal gland and melatonin in the development of autoimmune diabetes in non-obese diabetic mice.
Topics: Animals; Animals, Newborn; Autoantibodies; Autoimmune Diseases; Diabetes Mellitus; Female; Insulin; | 1996 |
Melatonin induces hyporeactivity caused by type II collagen in peripheral blood lymphocytes from patients with autoimmune hearing losses.
Topics: Adolescent; Adult; Aged; Autoimmune Diseases; Case-Control Studies; Cell Division; Child; Collagen; | 1997 |
[Lymphocytes of patients with auto-immune deafness present type II collagen hyporeactivity in the presence of the pineal hormone melatonin].
Topics: Adolescent; Adult; Aged; Autoimmune Diseases; Cell Movement; Collagen; Concanavalin A; Deafness; Fem | 2000 |
Coexisting bipolar affective disorder and multiple sclerosis: the role of the pineal gland.
Topics: Autoimmune Diseases; Bipolar Disorder; Circadian Rhythm; Depression; Humans; Immune Tolerance; Light | 1991 |