melatonin has been researched along with Autoimmune Diabetes in 17 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " Melatonin is neuroprotective against cerebral ischemia-reperfusion injury (CIRI) in non-DM, normoglycemic animals through anti-oxidant effect, anti-inflammation, and anti-apoptosis." | 8.31 | Melatonin mitigates type 1 diabetes-aggravated cerebral ischemia-reperfusion injury through anti-inflammatory and anti-apoptotic effects. ( Cheung, RTF; Xu, Q, 2023) |
| " Melatonin is neuroprotective against cerebral ischemia-reperfusion injury (CIRI) in non-DM, normoglycemic animals through anti-oxidant effect, anti-inflammation, and anti-apoptosis." | 4.31 | Melatonin mitigates type 1 diabetes-aggravated cerebral ischemia-reperfusion injury through anti-inflammatory and anti-apoptotic effects. ( Cheung, RTF; Xu, Q, 2023) |
| "Hyperglycemia increased retinal oxidation as measured through levels of nitrotyrosine and malondialdehyde." | 3.80 | Melatonin prevents retinal oxidative stress and vascular changes in diabetic rats. ( Bakariş, S; Durdu, H; Ergün, Y; Ganiyusufoğlu, E; Kılınç, M; Ozdemir, G, 2014) |
| "Our long-term goal is to determine the utility of melatonin in prevention of hypertension in type 1 diabetes." | 3.72 | Blood pressure-lowering effect of melatonin in type 1 diabetes. ( Bean, JA; Cavallo, A; Daniels, SR; Dolan, LM; Khoury, JC, 2004) |
| " We propose that dose-response studies of short- and long-acting preparations of melatonin be conducted and that melatonin be considered in trials of prevention of hypertension in type 1 diabetes." | 2.71 | Blood pressure response to melatonin in type 1 diabetes. ( Bean, JA; Cavallo, A; Daniels, SR; Dolan, LM; Khoury, JC, 2004) |
| "In total, 80 adult patients with type 1 diabetes (46% female) were included in a clinical cohort study." | 1.43 | Impact of sleep behavior on glycemic control in type 1 diabetes: the role of social jetlag. ( Benhamou, PY; Borel, AL; Gauchez, AS; Lablanche, S; Larcher, S; Pépin, JL, 2016) |
| "Melatonin is an important rhythmic endocrine signal within the circadian system of mammals and modulates insulin secretion and glucose metabolism." | 1.39 | Melatonin-receptor-1-deficiency affects neurogenic differentiation factor immunoreaction in pancreatic islets and enteroendocrine cells of mice. ( Fischer, C; Korf, HW; Shalabi, A; von Gall, C, 2013) |
| "Melatonin was also effective in restoring the impaired SNP-induced vasorelaxation seen in endothelium-denuded or L-NAME-treated aortic rings from hyperglycemic rats." | 1.33 | Melatonin restores endothelium-dependent relaxation in aortic rings of pancreatectomized rats. ( Cardinali, DP; Linares, LM; Obaya-Naredo, D; Pinto, JE; Reyes-Toso, CF; Ricci, CR; Rodríguez, RR, 2005) |
| " Dose-response curves for acetylcholine-induced, endothelium-related relaxation of aortic rings (after previous exposure to phenylephrine) and for phenylephrine-induced vasoconstriction were conducted." | 1.32 | Effect of melatonin on vascular reactivity in pancreatectomized rats. ( Arán, M; Cardinali, DP; Linares, LM; Pinto, JE; Reyes-Toso, CF; Ricci, CR; Rodríguez, RR, 2004) |
| " Dose-response curves for acetylcholine-induced, endothelium-related relaxation of aortic rings (after previous exposure to phenylephrine) and for serotonin-induced vasoconstriction were conducted in the presence or absence of 10-5 mol/L melatonin." | 1.31 | Vascular reactivity in diabetic rats: effect of melatonin. ( Albornoz, LE; Cardinali, DP; Damiano, PF; Linares, LM; Reyes-Toso, CF; Rosón, MI, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.88) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (35.29) | 29.6817 |
| 2010's | 7 (41.18) | 24.3611 |
| 2020's | 3 (17.65) | 2.80 |
| Authors | Studies |
|---|---|
| Gong, Z | 1 |
| Da, W | 1 |
| Tian, Y | 1 |
| Zhao, R | 1 |
| Qiu, S | 1 |
| Wu, Q | 1 |
| Wen, K | 1 |
| Shen, L | 1 |
| Zhou, R | 1 |
| Tao, L | 1 |
| Zhu, Y | 1 |
| Anderson, G | 1 |
| Xu, Q | 1 |
| Cheung, RTF | 1 |
| Shalabi, A | 1 |
| Fischer, C | 1 |
| Korf, HW | 1 |
| von Gall, C | 1 |
| Ozdemir, G | 1 |
| Ergün, Y | 1 |
| Bakariş, S | 1 |
| Kılınç, M | 1 |
| Durdu, H | 1 |
| Ganiyusufoğlu, E | 1 |
| Peschke, E | 3 |
| Bähr, I | 2 |
| Mühlbauer, E | 3 |
| Larcher, S | 1 |
| Gauchez, AS | 1 |
| Lablanche, S | 1 |
| Pépin, JL | 1 |
| Benhamou, PY | 1 |
| Borel, AL | 1 |
| Yu, L | 1 |
| Gong, B | 1 |
| Duan, W | 1 |
| Fan, C | 1 |
| Zhang, J | 1 |
| Li, Z | 1 |
| Xue, X | 1 |
| Xu, Y | 1 |
| Meng, D | 1 |
| Li, B | 1 |
| Zhang, M | 1 |
| Jin, Z | 1 |
| Yu, S | 1 |
| Yang, Y | 1 |
| Wang, H | 1 |
| Hofmann, K | 2 |
| Streck, S | 1 |
| Albrecht, E | 1 |
| Wedekind, D | 2 |
| Pönicke, K | 1 |
| Reyes-Toso, CF | 3 |
| Rosón, MI | 1 |
| Albornoz, LE | 1 |
| Damiano, PF | 1 |
| Linares, LM | 3 |
| Cardinali, DP | 3 |
| Cutando, A | 1 |
| Gómez-Moreno, G | 1 |
| Villalba, J | 1 |
| Ferrera, MJ | 1 |
| Escames, G | 1 |
| Acuña-Castroviejo, D | 1 |
| Cavallo, A | 2 |
| Daniels, SR | 2 |
| Dolan, LM | 2 |
| Khoury, JC | 2 |
| Bean, JA | 2 |
| Ricci, CR | 2 |
| Arán, M | 1 |
| Pinto, JE | 2 |
| Rodríguez, RR | 2 |
| Obaya-Naredo, D | 1 |
| Rittey, CD | 1 |
| Evans, TJ | 1 |
| Gray, CE | 1 |
| Paton, RD | 1 |
| Bojkowski, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Type 1 Diabetes on Sleep Fragmentation[NCT04601519] | 100 participants (Anticipated) | Observational | 2021-07-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for melatonin and Autoimmune Diabetes
| Article | Year |
|---|---|
Type I Diabetes Pathoetiology and Pathophysiology: Roles of the Gut Microbiome, Pancreatic Cellular Interactions, and the 'Bystander' Activation of Memory CD8
Topics: Brain-Derived Neurotrophic Factor; Butyrates; CD8-Positive T-Lymphocytes; Diabetes Mellitus, Type 1; | 2023 |
Experimental and clinical aspects of melatonin and clock genes in diabetes.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Gluc | 2015 |
1 trial available for melatonin and Autoimmune Diabetes
| Article | Year |
|---|---|
Blood pressure response to melatonin in type 1 diabetes.
Topics: Adolescent; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Diabetes Mellitus, Type 1; | 2004 |
14 other studies available for melatonin and Autoimmune Diabetes
| Article | Year |
|---|---|
Exogenous melatonin prevents type 1 diabetes mellitus-induced bone loss, probably by inhibiting senescence.
Topics: Animals; Diabetes Mellitus, Type 1; Melatonin; Mice; Mice, Inbred C57BL; Receptor, Melatonin, MT1; R | 2022 |
Melatonin mitigates type 1 diabetes-aggravated cerebral ischemia-reperfusion injury through anti-inflammatory and anti-apoptotic effects.
Topics: Animals; Brain Ischemia; Cerebral Infarction; Diabetes Mellitus, Type 1; Hyperglycemia; Infarction, | 2023 |
Melatonin-receptor-1-deficiency affects neurogenic differentiation factor immunoreaction in pancreatic islets and enteroendocrine cells of mice.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Diabetes Mellitus, Type 1; Diabetes Mellitus, | 2013 |
Melatonin prevents retinal oxidative stress and vascular changes in diabetic rats.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Retinopa | 2014 |
Impact of sleep behavior on glycemic control in type 1 diabetes: the role of social jetlag.
Topics: Adult; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; Female; Humans; Life Style; Male; | 2016 |
Melatonin ameliorates myocardial ischemia/reperfusion injury in type 1 diabetic rats by preserving mitochondrial function: role of AMPK-PGC-1α-SIRT3 signaling.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Cardiotonic Agents; Cytochromes c; Cytosol; Diabe | 2017 |
The insulin-melatonin antagonism: studies in the LEW.1AR1-iddm rat (an animal model of human type 1 diabetes mellitus).
Topics: Acetylserotonin O-Methyltransferase; Animals; ARNTL Transcription Factors; Arylalkylamine N-Acetyltr | 2011 |
Catecholamines are the key for explaining the biological relevance of insulin-melatonin antagonisms in type 1 and type 2 diabetes.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitu | 2012 |
Vascular reactivity in diabetic rats: effect of melatonin.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Aorta; Diabetes Mellitus, Experimental; Diabetes | 2002 |
Relationship between salivary melatonin levels and periodontal status in diabetic patients.
Topics: Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Humans; Interleukin-2; Male; Melatonin | 2003 |
Blood pressure-lowering effect of melatonin in type 1 diabetes.
Topics: Adolescent; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 1; Female; Humans; Hype | 2004 |
Effect of melatonin on vascular reactivity in pancreatectomized rats.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Aorta; Diabetes Mellitus, Experimental; Diabetes | 2004 |
Melatonin restores endothelium-dependent relaxation in aortic rings of pancreatectomized rats.
Topics: Acetylcholine; Animals; Aorta; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Endotheli | 2005 |
Melatonin state in Mendenhall's syndrome.
Topics: Diabetes Mellitus, Type 1; Humans; Hypoglycemia; Infant, Newborn; Insulin Resistance; Male; Melatoni | 1988 |