Page last updated: 2024-10-19

melatonin and Atrial Fibrillation

melatonin has been researched along with Atrial Fibrillation in 4 studies

Atrial Fibrillation: Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.

Research Excerpts

ExcerptRelevanceReference
"Angiotensin II (Ang II) induced Atrial fibrillation (AF) often accompanied with reduced ATRAP which is a negative modulator of Ang II type 1 receptor (AT1R)."8.12Melatonin inhibits angiotensin II-induced atrial fibrillation through preventing degradation of Ang II Type I Receptor-Associated Protein (ATRAP). ( Bi, HL; Liao, ZQ; Shen, TT; Shi, L; Su, ZL; Xia, YL; Xie, X; Zhang, Y, 2022)
"Melatonin is a hormone with anti-oxidant and anti-inflammatory properties in the cardiovascular system."7.01The Effects of Melatonin on the Oxidative Stress and Duration of Atrial Fibrillation after Coronary Artery Bypass Graft Surgery: A Randomized Controlled Trial. ( Ahmadi, ZH; Barati, S; Dastan, F; Jahangirifard, A; Tavakoli-Ardakani, M, 2021)
"Melatonin has been proven to have antiarrhythmic potential; however, several studies have recently challenged this view."5.91Melatonin increases susceptibility to atrial fibrillation in obesity via Akt signaling impairment in response to lipid overload. ( Fan, J; Fu, Y; Jiang, T; Liu, B; Liu, P; Qin, X; Zhang, Y; Zheng, Q, 2023)
"Melatonin treatment ameliorated BCAA-induced atrial damage and reversed BCAA-induced down-regulation of atrial PKGIα expression, CREB phosphorylation as well as KLF15 expression."5.72Activation of PKG-CREB-KLF15 by melatonin attenuates Angiotensin II-induced vulnerability to atrial fibrillation via enhancing branched-chain amino acids catabolism. ( Dong, X; Huang, YT; Luo, LY; Wang, HS; Wang, ZS; Xu, DY; Xu, YL; Xue, XD; Yu, LM; Zhao, JK; Zhao, QS; Zhou, ZJ, 2022)
"Angiotensin II (Ang II) induced Atrial fibrillation (AF) often accompanied with reduced ATRAP which is a negative modulator of Ang II type 1 receptor (AT1R)."4.12Melatonin inhibits angiotensin II-induced atrial fibrillation through preventing degradation of Ang II Type I Receptor-Associated Protein (ATRAP). ( Bi, HL; Liao, ZQ; Shen, TT; Shi, L; Su, ZL; Xia, YL; Xie, X; Zhang, Y, 2022)
"Melatonin is a hormone with anti-oxidant and anti-inflammatory properties in the cardiovascular system."3.01The Effects of Melatonin on the Oxidative Stress and Duration of Atrial Fibrillation after Coronary Artery Bypass Graft Surgery: A Randomized Controlled Trial. ( Ahmadi, ZH; Barati, S; Dastan, F; Jahangirifard, A; Tavakoli-Ardakani, M, 2021)
"Melatonin has been proven to have antiarrhythmic potential; however, several studies have recently challenged this view."1.91Melatonin increases susceptibility to atrial fibrillation in obesity via Akt signaling impairment in response to lipid overload. ( Fan, J; Fu, Y; Jiang, T; Liu, B; Liu, P; Qin, X; Zhang, Y; Zheng, Q, 2023)
"Melatonin treatment ameliorated BCAA-induced atrial damage and reversed BCAA-induced down-regulation of atrial PKGIα expression, CREB phosphorylation as well as KLF15 expression."1.72Activation of PKG-CREB-KLF15 by melatonin attenuates Angiotensin II-induced vulnerability to atrial fibrillation via enhancing branched-chain amino acids catabolism. ( Dong, X; Huang, YT; Luo, LY; Wang, HS; Wang, ZS; Xu, DY; Xu, YL; Xue, XD; Yu, LM; Zhao, JK; Zhao, QS; Zhou, ZJ, 2022)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's4 (100.00)2.80

Authors

AuthorsStudies
Yu, LM1
Dong, X1
Zhao, JK1
Xu, YL1
Xu, DY1
Xue, XD1
Zhou, ZJ1
Huang, YT1
Zhao, QS1
Luo, LY1
Wang, ZS1
Wang, HS1
Xie, X1
Shen, TT1
Bi, HL1
Su, ZL1
Liao, ZQ1
Zhang, Y2
Shi, L1
Xia, YL1
Qin, X1
Fu, Y1
Fan, J1
Liu, B1
Liu, P1
Jiang, T1
Zheng, Q1
Barati, S1
Jahangirifard, A1
Ahmadi, ZH1
Tavakoli-Ardakani, M1
Dastan, F1

Trials

1 trial available for melatonin and Atrial Fibrillation

ArticleYear
The Effects of Melatonin on the Oxidative Stress and Duration of Atrial Fibrillation after Coronary Artery Bypass Graft Surgery: A Randomized Controlled Trial.
    Endocrine, metabolic & immune disorders drug targets, 2021, Volume: 21, Issue:6

    Topics: Aged; Anti-Inflammatory Agents; Antioxidants; Atrial Fibrillation; Coronary Artery Bypass; Female; H

2021

Other Studies

3 other studies available for melatonin and Atrial Fibrillation

ArticleYear
Activation of PKG-CREB-KLF15 by melatonin attenuates Angiotensin II-induced vulnerability to atrial fibrillation via enhancing branched-chain amino acids catabolism.
    Free radical biology & medicine, 2022, Volume: 178

    Topics: Amino Acids, Branched-Chain; Angiotensin II; Atrial Fibrillation; Cyclic AMP Response Element-Bindin

2022
Melatonin inhibits angiotensin II-induced atrial fibrillation through preventing degradation of Ang II Type I Receptor-Associated Protein (ATRAP).
    Biochemical pharmacology, 2022, Volume: 202

    Topics: Angiotensin II; Animals; Atrial Fibrillation; Melatonin; Mice; Proteasome Endopeptidase Complex; Rec

2022
Melatonin increases susceptibility to atrial fibrillation in obesity via Akt signaling impairment in response to lipid overload.
    Journal of pineal research, 2023, Volume: 74, Issue:3

    Topics: Animals; Atrial Fibrillation; Insulin Resistance; Lipids; Melatonin; Mice; Mice, Obese; Obesity; Pro

2023