melatonin has been researched along with Atherosclerotic Parkinsonism in 13 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment of melatonin protected against nigral dopamine loss and replenished the striatal dopamine loss that resulted in amelioration of rotational behavioral bias in Hcy denervated animals." | 1.48 | Melatonin protects against behavioral deficits, dopamine loss and oxidative stress in homocysteine model of Parkinson's disease. ( Bhattacharya, P; Borah, A; Justin Thenmozhi, A; Manivasagam, T; Paul, R; Phukan, BC, 2018) |
| "Melatonin was administered intraperitoneally at a dose of 10 mg/kg/day for 30 days in M and Mel-6-OHDA groups, for 7 days in 6-OHDA-Mel group." | 1.42 | Melatonin is protective against 6-hydroxydopamine-induced oxidative stress in a hemiparkinsonian rat model. ( Agar, A; Aslan, M; Kaya, Y; Ogut, E; Ozsoy, O; Parlak, H; Tanriover, G; Yildirim, FB, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 7 (53.85) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| López, A | 1 |
| Ortiz, F | 1 |
| Doerrier, C | 1 |
| Venegas, C | 1 |
| Fernández-Ortiz, M | 1 |
| Aranda, P | 1 |
| Díaz-Casado, ME | 1 |
| Fernández-Gil, B | 1 |
| Barriocanal-Casado, E | 1 |
| Escames, G | 1 |
| López, LC | 1 |
| Acuña-Castroviejo, D | 2 |
| Paul, R | 1 |
| Phukan, BC | 1 |
| Justin Thenmozhi, A | 1 |
| Manivasagam, T | 2 |
| Bhattacharya, P | 1 |
| Borah, A | 1 |
| Naskar, A | 1 |
| Chakraborty, J | 1 |
| Singh, R | 1 |
| Thomas, B | 1 |
| Dhanasekaran, M | 1 |
| Mohanakumar, KP | 1 |
| Mattam, U | 1 |
| Jagota, A | 1 |
| Ozsoy, O | 1 |
| Yildirim, FB | 1 |
| Ogut, E | 1 |
| Kaya, Y | 1 |
| Tanriover, G | 1 |
| Parlak, H | 1 |
| Agar, A | 1 |
| Aslan, M | 1 |
| Labunets, IF | 1 |
| Talanov, SA | 1 |
| Vasilyev, RG | 1 |
| Rodnichenko, AE | 1 |
| Utko, NA | 1 |
| Kyzminova, IA | 1 |
| Kopjak, BS | 1 |
| Podjachenko, EV | 1 |
| Sagach, VF | 1 |
| Butenko, GM | 1 |
| Lin, L | 1 |
| Meng, T | 1 |
| Liu, T | 1 |
| Zheng, Z | 1 |
| Sharma, R | 1 |
| McMillan, CR | 1 |
| Tenn, CC | 1 |
| Niles, LP | 1 |
| Alvira, D | 1 |
| Tajes, M | 1 |
| Verdaguer, E | 1 |
| Folch, J | 1 |
| Camins, A | 1 |
| Pallas, M | 1 |
| Woodgate, A | 1 |
| MacGibbon, G | 1 |
| Walton, M | 1 |
| Dragunow, M | 1 |
| Absi, E | 1 |
| Ayala, A | 1 |
| Machado, A | 1 |
| Parrado, J | 1 |
| Dabbeni-Sala, F | 1 |
| Franceschini, D | 1 |
| Skaper, SD | 1 |
| Giusti, P | 1 |
| Burton, S | 1 |
| Daya, S | 1 |
| Potgieter, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Melatonin Administration on the PER1 and BMAL1 Clock Genes in Patients With Parkinson's Disease[NCT04287543] | Phase 2/Phase 3 | 0 participants (Actual) | Interventional | 2021-05-31 | Withdrawn (stopped due to Due to the COVID-19 pandemic, we were unable to begin the study) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
13 other studies available for melatonin and Atherosclerotic Parkinsonism
| Article | Year |
|---|---|
Mitochondrial impairment and melatonin protection in parkinsonian mice do not depend of inducible or neuronal nitric oxide synthases.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Gene Expression Regulation; | 2017 |
Melatonin protects against behavioral deficits, dopamine loss and oxidative stress in homocysteine model of Parkinson's disease.
Topics: Animals; Antioxidants; Behavior, Animal; Catecholamines; Dopamine; Dopaminergic Neurons; Electron Tr | 2018 |
Melatonin synergizes with low doses of L-DOPA to improve dendritic spine density in the mouse striatum in experimental Parkinsonism.
Topics: Animals; Antiparkinson Agents; Central Nervous System Depressants; Corpus Striatum; Dendrites; Dopam | 2013 |
Daily rhythms of serotonin metabolism and the expression of clock genes in suprachiasmatic nucleus of rotenone-induced Parkinson's disease male Wistar rat model and effect of melatonin administration.
Topics: Animals; ARNTL Transcription Factors; Circadian Rhythm; CLOCK Proteins; Cryptochromes; Disease Model | 2015 |
Melatonin is protective against 6-hydroxydopamine-induced oxidative stress in a hemiparkinsonian rat model.
Topics: Animals; Catalase; Drug Evaluation, Preclinical; Free Radical Scavengers; Glutathione Peroxidase; Li | 2015 |
[THYMIC HORMONES, ANTIOXIDANT ENZYMES AND NEUROGENESIS OF BULBUS OLFACTORIUS IN RATS WITH PARKINSONISM: THE EFFECT OF MELATONIN].
Topics: Animals; Antioxidants; Apomorphine; Ataxia; Catalase; Cell Count; Cell Differentiation; Dopamine Ago | 2015 |
Increased melatonin may play dual roles in the striata of a 6-hydroxydopamine model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Data | 2013 |
Physiological neuroprotection by melatonin in a 6-hydroxydopamine model of Parkinson's disease.
Topics: Animals; Apomorphine; Brain-Derived Neurotrophic Factor; Densitometry; Dopamine Agonists; Functional | 2006 |
Inhibition of the cdk5/p25 fragment formation may explain the antiapoptotic effects of melatonin in an experimental model of Parkinson's disease.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Calpain; Caspase 3; Caspases; Cell Survival; Cells, | 2006 |
The toxicity of 6-hydroxydopamine on PC12 and P19 cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Aurintricarboxylic Acid; Biological Transport; Bisbenzimi | 1999 |
Protective effect of melatonin against the 1-methyl-4-phenylpyridinium-induced inhibition of complex I of the mitochondrial respiratory chain.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Corpus Striatum; Electron Transport Complex I; Humans; In Vitr | 2000 |
Melatonin protects against 6-OHDA-induced neurotoxicity in rats: a role for mitochondrial complex I activity.
Topics: Adenosine Triphosphatases; Animals; Apomorphine; Behavior, Animal; Disease Models, Animal; Electron | 2001 |
Melatonin modulates apomorphine-induced rotational behaviour.
Topics: Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Hun | 1991 |