Page last updated: 2024-10-19

melatonin and Atheroma

melatonin has been researched along with Atheroma in 7 studies

Research Excerpts

ExcerptRelevanceReference
"Melatonin (MLT) is an endogenous indole compound with numerous biological activities that has been associated with atherosclerosis (AS)."7.81Melatonin alleviates myosin light chain kinase expression and activity via the mitogen-activated protein kinase pathway during atherosclerosis in rabbits. ( Cheng, X; Wan, Y; Wang, Y; Xu, Y; Zhou, Q; Zhu, H, 2015)
"Melatonin (MLT) is an endogenous indole compound with numerous biological activities that has been associated with atherosclerosis (AS)."3.81Melatonin alleviates myosin light chain kinase expression and activity via the mitogen-activated protein kinase pathway during atherosclerosis in rabbits. ( Cheng, X; Wan, Y; Wang, Y; Xu, Y; Zhou, Q; Zhu, H, 2015)
"Melatonin has atheroprotective effects by acting on different pathogenic signaling processes; these result from its direct free radical scavenger activity, its indirect antioxidant properties and its anti-inflammatory actions."2.50Melatonin and its atheroprotective effects: a review. ( Favero, G; Reiter, RJ; Rezzani, R; Rodella, LF, 2014)
"High-dose melatonin enhanced atherosclerotic plaque stability in ApoE mice in vivo by inducing the expression of P4Hα1, which was reversed by MTM."1.51Melatonin enhances atherosclerotic plaque stability by inducing prolyl-4-hydroxylase α1 expression. ( Chen, W; Jiang, X; Li, H; Li, J; Liu, S; Liu, Y; Yang, J; Zhang, C; Zhang, W, 2019)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (71.43)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Maity, J3
Dey, T3
Banerjee, A3
Chattopadhyay, A3
Das, AR3
Bandyopadhyay, D3
Hu, ZP1
Fang, XL1
Sheng, B1
Guo, Y1
Yu, YQ1
Ma, S1
Chen, J1
Feng, J1
Zhang, R1
Fan, M1
Han, D1
Li, X1
Li, C1
Ren, J1
Wang, Y2
Cao, F1
Li, H1
Li, J1
Jiang, X1
Liu, S1
Liu, Y1
Chen, W1
Yang, J1
Zhang, C1
Zhang, W1
Ding, S1
Lin, N1
Sheng, X1
Zhao, Y1
Su, Y1
Xu, L1
Tong, R1
Yan, Y1
Fu, Y1
He, J1
Gao, Y1
Yuan, A1
Ye, L1
Reiter, RJ2
Pu, J1
Favero, G1
Rodella, LF1
Rezzani, R1
Cheng, X1
Wan, Y1
Xu, Y1
Zhou, Q1
Zhu, H1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Intervention Effect Of Melatonin On The Risk Of Cardiovascular Events And Malignant Tumors In The Elderly: A Prospective, Randomized Parallel Controlled Study Based On Large Cohorts[NCT04631341]10,000 participants (Anticipated)Interventional2021-01-01Not yet recruiting
Melatonin and Essential Arterial Hypertension[NCT05257291]Phase 223 participants (Actual)Interventional2018-02-02Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for melatonin and Atheroma

ArticleYear
Melatonin ameliorates myocardial infarction in obese diabetic individuals: The possible involvement of macrophage apoptotic factors.
    Journal of pineal research, 2023, Volume: 74, Issue:2

    Topics: Anti-Inflammatory Agents; Antioxidants; Apoptosis; Cholesterol; Diabetes Mellitus, Type 2; Humans; M

2023
Melatonin ameliorates myocardial infarction in obese diabetic individuals: The possible involvement of macrophage apoptotic factors.
    Journal of pineal research, 2023, Volume: 74, Issue:2

    Topics: Anti-Inflammatory Agents; Antioxidants; Apoptosis; Cholesterol; Diabetes Mellitus, Type 2; Humans; M

2023
Melatonin ameliorates myocardial infarction in obese diabetic individuals: The possible involvement of macrophage apoptotic factors.
    Journal of pineal research, 2023, Volume: 74, Issue:2

    Topics: Anti-Inflammatory Agents; Antioxidants; Apoptosis; Cholesterol; Diabetes Mellitus, Type 2; Humans; M

2023
Melatonin ameliorates myocardial infarction in obese diabetic individuals: The possible involvement of macrophage apoptotic factors.
    Journal of pineal research, 2023, Volume: 74, Issue:2

    Topics: Anti-Inflammatory Agents; Antioxidants; Apoptosis; Cholesterol; Diabetes Mellitus, Type 2; Humans; M

2023
Melatonin and its atheroprotective effects: a review.
    Molecular and cellular endocrinology, 2014, Feb-15, Volume: 382, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Atherosclerosis; Gene Expression Regulation; Humans

2014

Other Studies

5 other studies available for melatonin and Atheroma

ArticleYear
Melatonin inhibits macrophage infiltration and promotes plaque stabilization by upregulating anti-inflammatory HGF/c-Met system in the atherosclerotic rabbit: USPIO-enhanced MRI assessment.
    Vascular pharmacology, 2020, Volume: 127

    Topics: Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aortic Diseases; Atherosclerosis; Contrast Medi

2020
Melatonin Ameliorates the Progression of Atherosclerosis via Mitophagy Activation and NLRP3 Inflammasome Inhibition.
    Oxidative medicine and cellular longevity, 2018, Volume: 2018

    Topics: Animals; Atherosclerosis; Disease Progression; Forkhead Box Protein O3; Free Radical Scavengers; Inf

2018
Melatonin enhances atherosclerotic plaque stability by inducing prolyl-4-hydroxylase α1 expression.
    Journal of hypertension, 2019, Volume: 37, Issue:5

    Topics: Animals; Apolipoproteins E; Cell Line; Central Nervous System Depressants; Chromones; Enzyme Inhibit

2019
Melatonin stabilizes rupture-prone vulnerable plaques via regulating macrophage polarization in a nuclear circadian receptor RORα-dependent manner.
    Journal of pineal research, 2019, Volume: 67, Issue:2

    Topics: Animals; Atherosclerosis; Humans; Macrophages; Male; Melatonin; Mice; Mice, Knockout, ApoE; Nuclear

2019
Melatonin alleviates myosin light chain kinase expression and activity via the mitogen-activated protein kinase pathway during atherosclerosis in rabbits.
    Molecular medicine reports, 2015, Volume: 11, Issue:1

    Topics: Animals; Aorta; Atherosclerosis; Capillary Permeability; Disease Models, Animal; Extracellular Signa

2015