Page last updated: 2024-10-19

melatonin and Astrocytoma

melatonin has been researched along with Astrocytoma in 7 studies

Astrocytoma: Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)

Research Excerpts

ExcerptRelevanceReference
" Because hypothalamic lesions may explain daytime sleepiness in craniopharyngioma patients, salivary melatonin and cortisol concentrations were examined in severely obese (BMI>or=4SD) and non severely obese (BMI<4SD) craniopharyngioma patients (n=79), patients with hypothalamic pilocytic astrocytoma (n=19), and control subjects (n=30)."7.73Melatonin treatment in obese patients with childhood craniopharyngioma and increased daytime sleepiness. ( Emser, A; Faldum, A; Gebhardt, U; Handwerker, G; Kolb, R; Müller, HL; Sörensen, N, 2006)
" Because hypothalamic lesions may explain daytime sleepiness in craniopharyngioma patients, salivary melatonin and cortisol concentrations were examined in obese and nonobese craniopharyngioma patients (n = 79), patients with hypothalamic pilocytic astrocytoma (n = 19), and control subjects (n = 30)."7.71Melatonin secretion and increased daytime sleepiness in childhood craniopharyngioma patients. ( Faldum, A; Handwerker, G; Müller, HL; Sörensen, N; Wollny, B, 2002)
"Melatonin has been known to affect a variety of astrocytes functions in many neurological disorders but its mechanism of action on neuroinflammatory cascade and alpha-7 nicotinic acetylcholine receptor (α7-nAChR) expression are still not properly understood."5.38Melatonin attenuated mediators of neuroinflammation and alpha-7 nicotinic acetylcholine receptor mRNA expression in lipopolysaccharide (LPS) stimulated rat astrocytoma cells, C6. ( Nath, C; Niranjan, R; Shukla, R, 2012)
"Treatment of melatonin with MPTP reversed all these MPTP-induced changes."5.36The mechanism of action of MPTP-induced neuroinflammation and its modulation by melatonin in rat astrocytoma cells, C6. ( Nath, C; Niranjan, R; Shukla, R, 2010)
"Melatonin is a neurohormone that regulates target cells via binding to specific high-affinity plasma membrane receptors, MT1/MT2."5.35Neuroprotection by melatonin on astrocytoma cell death. ( Ghibelli, L; Mengoni, F; Nuccitelli, S; Radogna, F, 2009)
" Because hypothalamic lesions may explain daytime sleepiness in craniopharyngioma patients, salivary melatonin and cortisol concentrations were examined in severely obese (BMI>or=4SD) and non severely obese (BMI<4SD) craniopharyngioma patients (n=79), patients with hypothalamic pilocytic astrocytoma (n=19), and control subjects (n=30)."3.73Melatonin treatment in obese patients with childhood craniopharyngioma and increased daytime sleepiness. ( Emser, A; Faldum, A; Gebhardt, U; Handwerker, G; Kolb, R; Müller, HL; Sörensen, N, 2006)
" Because hypothalamic lesions may explain daytime sleepiness in craniopharyngioma patients, salivary melatonin and cortisol concentrations were examined in obese and nonobese craniopharyngioma patients (n = 79), patients with hypothalamic pilocytic astrocytoma (n = 19), and control subjects (n = 30)."3.71Melatonin secretion and increased daytime sleepiness in childhood craniopharyngioma patients. ( Faldum, A; Handwerker, G; Müller, HL; Sörensen, N; Wollny, B, 2002)
"Melatonin has been known to affect a variety of astrocytes functions in many neurological disorders but its mechanism of action on neuroinflammatory cascade and alpha-7 nicotinic acetylcholine receptor (α7-nAChR) expression are still not properly understood."1.38Melatonin attenuated mediators of neuroinflammation and alpha-7 nicotinic acetylcholine receptor mRNA expression in lipopolysaccharide (LPS) stimulated rat astrocytoma cells, C6. ( Nath, C; Niranjan, R; Shukla, R, 2012)
"Treatment of melatonin with MPTP reversed all these MPTP-induced changes."1.36The mechanism of action of MPTP-induced neuroinflammation and its modulation by melatonin in rat astrocytoma cells, C6. ( Nath, C; Niranjan, R; Shukla, R, 2010)
"Melatonin is a neurohormone that regulates target cells via binding to specific high-affinity plasma membrane receptors, MT1/MT2."1.35Neuroprotection by melatonin on astrocytoma cell death. ( Ghibelli, L; Mengoni, F; Nuccitelli, S; Radogna, F, 2009)
"Melatonin is a potent antioxidant and free radical scavenger."1.32Protective effect of melatonin on beta-amyloid-induced apoptosis in rat astroglioma C6 cells and its mechanism. ( Feng, Z; Zhang, JT, 2004)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's0 (0.00)18.2507
2000's4 (57.14)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Radogna, F1
Nuccitelli, S1
Mengoni, F1
Ghibelli, L1
Niranjan, R2
Nath, C2
Shukla, R2
Müller, HL2
Handwerker, G2
Wollny, B1
Faldum, A2
Sörensen, N2
Feng, Z1
Zhang, JT1
Gebhardt, U1
Emser, A1
Kolb, R1
Neuwelt, EA1
Lewy, AJ1

Other Studies

7 other studies available for melatonin and Astrocytoma

ArticleYear
Neuroprotection by melatonin on astrocytoma cell death.
    Annals of the New York Academy of Sciences, 2009, Volume: 1171

    Topics: Antioxidants; Apoptosis; Astrocytoma; Benzoquinones; Biological Transport; Calcium; Calcium Channel

2009
The mechanism of action of MPTP-induced neuroinflammation and its modulation by melatonin in rat astrocytoma cells, C6.
    Free radical research, 2010, Volume: 44, Issue:11

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Astrocytes; Astrocytoma; Blotting, Western; C

2010
Melatonin attenuated mediators of neuroinflammation and alpha-7 nicotinic acetylcholine receptor mRNA expression in lipopolysaccharide (LPS) stimulated rat astrocytoma cells, C6.
    Free radical research, 2012, Volume: 46, Issue:9

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Anti-Inflammatory Agents; Astrocytoma; Cytokines;

2012
Melatonin secretion and increased daytime sleepiness in childhood craniopharyngioma patients.
    The Journal of clinical endocrinology and metabolism, 2002, Volume: 87, Issue:8

    Topics: Adolescent; Adult; Astrocytoma; Child; Child, Preschool; Craniopharyngioma; Female; Humans; Hydrocor

2002
Protective effect of melatonin on beta-amyloid-induced apoptosis in rat astroglioma C6 cells and its mechanism.
    Free radical biology & medicine, 2004, Dec-01, Volume: 37, Issue:11

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Astrocytes; Astrocytoma; Calcium; Cell

2004
Melatonin treatment in obese patients with childhood craniopharyngioma and increased daytime sleepiness.
    Cancer causes & control : CCC, 2006, Volume: 17, Issue:4

    Topics: Adolescent; Adult; Astrocytoma; Child; Child, Preschool; Circadian Rhythm; Craniopharyngioma; Disord

2006
Disappearance of plasma melatonin after removal of a neoplastic pineal gland.
    The New England journal of medicine, 1983, May-12, Volume: 308, Issue:19

    Topics: Adolescent; Astrocytoma; Brain Neoplasms; Circadian Rhythm; Gas Chromatography-Mass Spectrometry; Hu

1983