melatonin has been researched along with Anesthesia in 16 studies
Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Midazolam is more effective than melatonin in reducing children's anxiety at induction of anesthesia." | 9.14 | Preoperative melatonin and its effects on induction and emergence in children undergoing anesthesia and surgery. ( Hata, J; Herrmann, L; Kain, ZN; Lerman, J; MacLaren, JE; Mayes, L; Rosenbaum, A, 2009) |
| "Endoplasmic reticulum (ER) stress has been linked to anesthesia-induced neurotoxicity, but melatonin seems to play a protective role against ER stress." | 8.12 | Melatonin reduces the endoplasmic reticulum stress and polyubiquitinated protein accumulation induced by repeated anesthesia exposure in Caenorhabditis elegans. ( Do, SH; Kim, H; Koo, BW; Na, HS; Shin, HJ; Yoon, J, 2022) |
| "Isoflurane anesthesia alters the blood levels of several neuroendocrine hormones associated with normal metabolism and physiology and increases stress, but the effect of brief CO2 anesthesia on these parameters is unknown." | 7.85 | Effect of Isoflurane Anesthesia on Circadian Metabolism and Physiology in Rats. ( Blask, DE; Bohm, RP; Dauchy, RT; Dupepe, LM; Hill, SM; Ooms, TG; Wren-Dail, MA, 2017) |
| "Melatonin pretreatment caused rapid onset of anesthesia after ketamine and thiopental sodium administration while the duration of action of these agents was prolonged." | 5.33 | Adjuvant effect of melatonin on anesthesia induced by thiopental sodium, ketamine, and ether in rats. ( Budhiraja, S; Singh, J, 2005) |
| "Midazolam is more effective than melatonin in reducing children's anxiety at induction of anesthesia." | 5.14 | Preoperative melatonin and its effects on induction and emergence in children undergoing anesthesia and surgery. ( Hata, J; Herrmann, L; Kain, ZN; Lerman, J; MacLaren, JE; Mayes, L; Rosenbaum, A, 2009) |
| "Endoplasmic reticulum (ER) stress has been linked to anesthesia-induced neurotoxicity, but melatonin seems to play a protective role against ER stress." | 4.12 | Melatonin reduces the endoplasmic reticulum stress and polyubiquitinated protein accumulation induced by repeated anesthesia exposure in Caenorhabditis elegans. ( Do, SH; Kim, H; Koo, BW; Na, HS; Shin, HJ; Yoon, J, 2022) |
| "Isoflurane anesthesia alters the blood levels of several neuroendocrine hormones associated with normal metabolism and physiology and increases stress, but the effect of brief CO2 anesthesia on these parameters is unknown." | 3.85 | Effect of Isoflurane Anesthesia on Circadian Metabolism and Physiology in Rats. ( Blask, DE; Bohm, RP; Dauchy, RT; Dupepe, LM; Hill, SM; Ooms, TG; Wren-Dail, MA, 2017) |
| "Melatonin was associated with reduced sedative effects, post-operative excitement and improved emergence behaviour, compared to comparator drugs." | 2.82 | Melatonin for pre-medication in children: a systematic review. ( Bolt, R; Deery, C; Evans, C; Mellor, K; Papaioannou, D; Thomason, A; Wilson, M, 2022) |
| "Postoperative delirium is a common sequela in older adults in the peri-operative period leading to poor outcomes with a complex pathophysiology which has led to a variety of different pharmacologic agents employed in attempts to prevent and treat this syndrome." | 2.66 | The pharmacotherapeutic management of postoperative delirium: an expert update. ( Scicutella, A, 2020) |
| "Melatonin pretreatment caused rapid onset of anesthesia after ketamine and thiopental sodium administration while the duration of action of these agents was prolonged." | 1.33 | Adjuvant effect of melatonin on anesthesia induced by thiopental sodium, ketamine, and ether in rats. ( Budhiraja, S; Singh, J, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.25) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 5 (31.25) | 29.6817 |
| 2010's | 4 (25.00) | 24.3611 |
| 2020's | 5 (31.25) | 2.80 |
| Authors | Studies |
|---|---|
| Mellor, K | 1 |
| Papaioannou, D | 1 |
| Thomason, A | 1 |
| Bolt, R | 1 |
| Evans, C | 1 |
| Wilson, M | 1 |
| Deery, C | 1 |
| Shin, HJ | 1 |
| Koo, BW | 1 |
| Yoon, J | 1 |
| Kim, H | 1 |
| Do, SH | 1 |
| Na, HS | 1 |
| Eom, S | 3 |
| Lee, S | 3 |
| Lee, J | 3 |
| Sohn, SO | 3 |
| Lee, JH | 3 |
| Park, J | 3 |
| Scicutella, A | 1 |
| Procaccini, D | 1 |
| Lobner, K | 1 |
| Azamfirei, R | 1 |
| Kudchadkar, SR | 1 |
| Wren-Dail, MA | 1 |
| Dauchy, RT | 1 |
| Blask, DE | 1 |
| Hill, SM | 1 |
| Ooms, TG | 1 |
| Dupepe, LM | 1 |
| Bohm, RP | 1 |
| Mistraletti, G | 1 |
| Umbrello, M | 1 |
| Salini, S | 1 |
| Cadringher, P | 1 |
| Formenti, P | 1 |
| Chiumello, D | 1 |
| Villa, C | 1 |
| Russo, R | 1 |
| Francesconi, S | 1 |
| Valdambrini, F | 1 |
| Bellani, G | 1 |
| Palo, A | 1 |
| Riccardi, F | 1 |
| Ferretti, E | 1 |
| Festa, M | 1 |
| Gado, AM | 1 |
| Taverna, M | 1 |
| Pinna, C | 1 |
| Barbiero, A | 1 |
| Ferrari, PA | 1 |
| Iapichino, G | 1 |
| Knaus, V | 1 |
| Mühler, R | 1 |
| Verhey, JL | 1 |
| Aras, HC | 1 |
| Ekström, J | 1 |
| Kain, ZN | 1 |
| MacLaren, JE | 1 |
| Herrmann, L | 1 |
| Mayes, L | 1 |
| Rosenbaum, A | 1 |
| Hata, J | 1 |
| Lerman, J | 1 |
| Grossini, E | 1 |
| Molinari, C | 1 |
| Uberti, F | 1 |
| Mary, DA | 1 |
| Vacca, G | 1 |
| Caimmi, PP | 1 |
| Budhiraja, S | 1 |
| Singh, J | 1 |
| Naguib, M | 1 |
| Gottumukkala, V | 1 |
| Goldstein, PA | 1 |
| Withyachumnarnkul, B | 1 |
| Knigge, KM | 1 |
| Kato, K | 1 |
| Murai, I | 1 |
| Asai, S | 1 |
| Takahashi, Y | 1 |
| Matsuno, Y | 1 |
| Komuro, S | 1 |
| Kurosaka, H | 1 |
| Iwasaki, A | 1 |
| Ishikawa, K | 1 |
| Arakawa, Y | 1 |
| Lin, AM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Multicentric, Single Blind, Randomized Controlled Trial on Enteral Sedation Versus Intravenous Sedation in Critically Ill High-risk ICU Patients[NCT01360346] | Phase 3 | 300 participants (Anticipated) | Interventional | 2012-01-31 | Recruiting | ||
| Effects of Procedure Started in the Morning and Afternoon on Early Postoperative Sleep Function and Postoperative Recovery in Patients Under General Anesthesia[NCT04103528] | 62 participants (Actual) | Interventional | 2018-10-09 | Completed | |||
| Assessment of the Effects of Melatonin on Preoperative Anxiety and Postoperative Analgesia in Children Undergoing Surgery: a Prospective, Randomized Clinical Trial[NCT02265822] | Phase 4 | 92 participants (Actual) | Interventional | 2012-09-30 | Completed | ||
| Relationship Between Melatonin Level and Postoperative Analgesia Consumption in Bariatric Surgery Patients.[NCT03107702] | 35 participants (Anticipated) | Observational | 2017-03-29 | Enrolling by invitation | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for melatonin and Anesthesia
| Article | Year |
|---|---|
Melatonin for pre-medication in children: a systematic review.
Topics: Adult; Anesthesia; Anti-Anxiety Agents; Anxiety; Child; Humans; Hypnotics and Sedatives; Melatonin | 2022 |
The pharmacotherapeutic management of postoperative delirium: an expert update.
Topics: Aged; Analgesia; Anesthesia; Antipsychotic Agents; Delirium; Dexmedetomidine; Drug Monitoring; Human | 2020 |
Melatonin for anaesthetic indications in paediatric patients: a systematic review.
Topics: Adolescent; Anesthesia; Central Nervous System Depressants; Child; Child, Preschool; Humans; Infant; | 2021 |
Melatonin and anesthesia: a clinical perspective.
Topics: Anesthesia; Animals; Binding Sites; Central Nervous System; Humans; Melatonin; Surgical Procedures, | 2007 |
Melatonin and anesthesia: a clinical perspective.
Topics: Anesthesia; Animals; Binding Sites; Central Nervous System; Humans; Melatonin; Surgical Procedures, | 2007 |
Melatonin and anesthesia: a clinical perspective.
Topics: Anesthesia; Animals; Binding Sites; Central Nervous System; Humans; Melatonin; Surgical Procedures, | 2007 |
Melatonin and anesthesia: a clinical perspective.
Topics: Anesthesia; Animals; Binding Sites; Central Nervous System; Humans; Melatonin; Surgical Procedures, | 2007 |
Melatonin and anesthesia: a clinical perspective.
Topics: Anesthesia; Animals; Binding Sites; Central Nervous System; Humans; Melatonin; Surgical Procedures, | 2007 |
Melatonin and anesthesia: a clinical perspective.
Topics: Anesthesia; Animals; Binding Sites; Central Nervous System; Humans; Melatonin; Surgical Procedures, | 2007 |
Melatonin and anesthesia: a clinical perspective.
Topics: Anesthesia; Animals; Binding Sites; Central Nervous System; Humans; Melatonin; Surgical Procedures, | 2007 |
Melatonin and anesthesia: a clinical perspective.
Topics: Anesthesia; Animals; Binding Sites; Central Nervous System; Humans; Melatonin; Surgical Procedures, | 2007 |
Melatonin and anesthesia: a clinical perspective.
Topics: Anesthesia; Animals; Binding Sites; Central Nervous System; Humans; Melatonin; Surgical Procedures, | 2007 |
2 trials available for melatonin and Anesthesia
| Article | Year |
|---|---|
Enteral versus intravenous approach for the sedation of critically ill patients: a randomized and controlled trial.
Topics: Aged; Anesthesia; Antipruritics; Central Nervous System Depressants; Critical Illness; Deep Sedation | 2019 |
Preoperative melatonin and its effects on induction and emergence in children undergoing anesthesia and surgery.
Topics: Adult; Anesthesia; Anesthesia Recovery Period; Anxiety; Child; Child, Preschool; Female; Follow-Up S | 2009 |
10 other studies available for melatonin and Anesthesia
| Article | Year |
|---|---|
Melatonin reduces the endoplasmic reticulum stress and polyubiquitinated protein accumulation induced by repeated anesthesia exposure in Caenorhabditis elegans.
Topics: Anesthesia; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Endoplasmic Reticulum | 2022 |
A Combination of Rosa Multiflora and Zizyphus Jujuba Enhance Sleep Quality in Anesthesia-Induced Mice.
Topics: Anesthesia; Animals; Melatonin; Mice; Quality of Life; Rosa; Sleep Quality; Ziziphus | 2022 |
A Combination of Rosa Multiflora and Zizyphus Jujuba Enhance Sleep Quality in Anesthesia-Induced Mice.
Topics: Anesthesia; Animals; Melatonin; Mice; Quality of Life; Rosa; Sleep Quality; Ziziphus | 2022 |
A Combination of Rosa Multiflora and Zizyphus Jujuba Enhance Sleep Quality in Anesthesia-Induced Mice.
Topics: Anesthesia; Animals; Melatonin; Mice; Quality of Life; Rosa; Sleep Quality; Ziziphus | 2022 |
A Combination of Rosa Multiflora and Zizyphus Jujuba Enhance Sleep Quality in Anesthesia-Induced Mice.
Topics: Anesthesia; Animals; Melatonin; Mice; Quality of Life; Rosa; Sleep Quality; Ziziphus | 2022 |
A Combination of Rosa Multiflora and Zizyphus Jujuba Enhance Sleep Quality in Anesthesia-Induced Mice.
Topics: Anesthesia; Animals; Melatonin; Mice; Quality of Life; Rosa; Sleep Quality; Ziziphus | 2022 |
A Combination of Rosa Multiflora and Zizyphus Jujuba Enhance Sleep Quality in Anesthesia-Induced Mice.
Topics: Anesthesia; Animals; Melatonin; Mice; Quality of Life; Rosa; Sleep Quality; Ziziphus | 2022 |
A Combination of Rosa Multiflora and Zizyphus Jujuba Enhance Sleep Quality in Anesthesia-Induced Mice.
Topics: Anesthesia; Animals; Melatonin; Mice; Quality of Life; Rosa; Sleep Quality; Ziziphus | 2022 |
A Combination of Rosa Multiflora and Zizyphus Jujuba Enhance Sleep Quality in Anesthesia-Induced Mice.
Topics: Anesthesia; Animals; Melatonin; Mice; Quality of Life; Rosa; Sleep Quality; Ziziphus | 2022 |
A Combination of Rosa Multiflora and Zizyphus Jujuba Enhance Sleep Quality in Anesthesia-Induced Mice.
Topics: Anesthesia; Animals; Melatonin; Mice; Quality of Life; Rosa; Sleep Quality; Ziziphus | 2022 |
Effect of Isoflurane Anesthesia on Circadian Metabolism and Physiology in Rats.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Blood Glucose; Circadian Clocks; Corticosterone; Fatty | 2017 |
[Determination of hearing thresholds in children using auditory brainstem responses : Influence of sedation and anaesthesia on quality and measurement time].
Topics: Anesthesia; Auditory Threshold; Child; Child, Preschool; Chloral Hydrate; Evoked Potentials, Auditor | 2019 |
Melatonin-evoked in vivo secretion of protein and amylase from the parotid gland of the anaesthetised rat.
Topics: Amylases; Analysis of Variance; Anesthesia; Animals; Autonomic Denervation; Blotting, Western; Femal | 2008 |
Intracoronary melatonin increases coronary blood flow and cardiac function through β-adrenoreceptors, MT1/MT2 receptors, and nitric oxide in anesthetized pigs.
Topics: Anesthesia; Animals; Antioxidants; Blood Flow Velocity; Coronary Circulation; Heart Rate; Melatonin; | 2011 |
Adjuvant effect of melatonin on anesthesia induced by thiopental sodium, ketamine, and ether in rats.
Topics: Adjuvants, Anesthesia; Anesthesia; Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, In | 2005 |
Melatonin concentration in cerebrospinal fluid, peripheral plasma and plasma of the confluens sinuum of the rat.
Topics: Anesthesia; Animals; Darkness; Dura Mater; Kinetics; Male; Melatonin; Pineal Gland; Radioimmunoassay | 1980 |
Central nervous system action of melatonin on gastric acid and pepsin secretion in pylorus-ligated rats.
Topics: Anesthesia; Animals; Antioxidants; Central Nervous System; Cisterna Magna; Gastric Acid; Gastric Muc | 1998 |
Coexistence of zinc and iron augmented oxidative injuries in the nigrostriatal dopaminergic system of SD rats.
Topics: Anesthesia; Animals; Brain; Corpus Striatum; Deferoxamine; Dopamine; Drug Interactions; Glutathione; | 2001 |