melatonin has been researched along with American Trypanosomiasis in 15 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "With melatonin treatment, orchiectomized animals (CMOR and IMOR) displayed the highest concentrations of IFN-γ and TNF-α." | 5.38 | Does orchiectomy enhance the immune-stimulatory effects of melatonin during experimental Chagas' disease? ( Brazão, V; Caetano, LC; Caetano, LN; do Prado, JC; Filipin, Mdel V; Santello, FH; Toldo, MP, 2012) |
| "Chagas' disease is a severe health problem in Latin America, causing approximately 50 000 deaths a year, with approximately 18 million infected people." | 5.37 | Melatonin in Chagas' disease. Possible therapeutic value. ( Alvarez, CB; Cardinali, DP, 2011) |
| "The melatonin therapy was provided in one of two different treatment regimens, that is, either beginning 7 days prior to infection or concomitant with the infection." | 5.35 | Melatonin enhances pro-inflammatory cytokine levels and protects against Chagas disease. ( AlonsoToldo, MP; Caetano, LC; do Prado, JC; Frare, EO; Santello, FH, 2008) |
| "Melatonin has remarkably diverse actions." | 2.66 | T. cruzi infection among aged rats: Melatonin as a promising therapeutic molecule. ( Brazão, V; Colato, RP; do Prado, JC; Santello, FH, 2020) |
| "Melatonin (MEL) has emerged as a promising therapy for CD due to its antioxidant and immunomodulatory properties; however, the protective action of MEL in the cardiac tissue, as well as its direct action on the parasite cycle, is not fully understood." | 1.62 | Melatonin decreases circulating ( Anchieta, NF; da Silva, CBP; de Albuquerque, S; Oliveira, PAS; Portapilla, GB; Providello, MV; Tirapelli, CR, 2021) |
| "Melatonin has a remarkable functional versatility, being associated with important antioxidant, anti-inflammatory, and anti-apoptotic effects." | 1.42 | Immunoregulatory actions of melatonin and zinc during chronic Trypanosoma cruzi infection. ( Azevedo, AP; Brazão, V; de Morais, FR; do Prado, JC; Filipin, Mdel V; Santello, FH; Toldo, MP, 2015) |
| "With melatonin treatment, orchiectomized animals (CMOR and IMOR) displayed the highest concentrations of IFN-γ and TNF-α." | 1.38 | Does orchiectomy enhance the immune-stimulatory effects of melatonin during experimental Chagas' disease? ( Brazão, V; Caetano, LC; Caetano, LN; do Prado, JC; Filipin, Mdel V; Santello, FH; Toldo, MP, 2012) |
| "The etiology of Chagas' disease, caused by a protozoan parasite Trypanosoma cruzi, has been the focus of considerable discussion, although chronic phase still remains not fully understood." | 1.37 | Melatonin and zinc treatment: distinctive modulation of cytokine production in chronic experimental Trypanosoma cruzi infection. ( Abrahão, AA; Brazão, V; Caetano, LC; Del Vecchio Filipin, M; do Prado, JC; Santello, FH; Toldo, MP, 2011) |
| "Chagas' disease is a severe health problem in Latin America, causing approximately 50 000 deaths a year, with approximately 18 million infected people." | 1.37 | Melatonin in Chagas' disease. Possible therapeutic value. ( Alvarez, CB; Cardinali, DP, 2011) |
| "Treatment with melatonin, DHEA and the association showed a significant reduction in the number of blood trypomastigotes during the acute phase of infection as compared to untreated animals (P < 0." | 1.35 | Melatonin and dehydroepiandrosterone combination: does this treatment exert a synergistic effect during experimental Trypanosoma cruzi infection? ( Alonso Toldo, MP; de Albuquerque, S; do Prado, JC; Ferreira, DS; Kuehn, CC; Rodrigues Oliveira, LG; Santos, CD, 2009) |
| "The melatonin therapy was provided in one of two different treatment regimens, that is, either beginning 7 days prior to infection or concomitant with the infection." | 1.35 | Melatonin enhances pro-inflammatory cytokine levels and protects against Chagas disease. ( AlonsoToldo, MP; Caetano, LC; do Prado, JC; Frare, EO; Santello, FH, 2008) |
| "Melatonin is an effective regulator of the immune system." | 1.35 | Suppressive action of melatonin on the TH-2 immune response in rats infected with Trypanosoma cruzi. ( Alonso Toldo, MP; Caetano, LC; do Prado, JC; dos Santos, CD; Frare, EO; Santello, FH, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (33.33) | 29.6817 |
| 2010's | 8 (53.33) | 24.3611 |
| 2020's | 2 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Brazão, V | 8 |
| Santello, FH | 11 |
| Colato, RP | 3 |
| do Prado, JC | 12 |
| Providello, MV | 1 |
| Portapilla, GB | 1 |
| Oliveira, PAS | 1 |
| da Silva, CBP | 1 |
| Anchieta, NF | 1 |
| Tirapelli, CR | 3 |
| de Albuquerque, S | 2 |
| Mazotti, TT | 1 |
| Tazinafo, LF | 1 |
| Toldo, MPA | 1 |
| do Vale, GT | 1 |
| Vale, GTD | 1 |
| Gonzaga, NA | 1 |
| Prado, JCD | 1 |
| Filipin, Mdel V | 3 |
| Azevedo, AP | 2 |
| Toldo, MP | 6 |
| de Morais, FR | 2 |
| Del Vecchio Filipin, M | 2 |
| Caetano, LC | 5 |
| Caetano, LN | 2 |
| Dos Santos, CD | 3 |
| Alonso Toldo, MP | 3 |
| Kuehn, CC | 2 |
| Rodrigues Oliveira, LG | 1 |
| Santos, CD | 2 |
| Ferreira, DS | 1 |
| Oliveira, LG | 1 |
| Abrahão, AA | 1 |
| Cardinali, DP | 1 |
| Alvarez, CB | 1 |
| Frare, EO | 3 |
| Kawasse, LM | 1 |
| Zucoloto, S | 1 |
| AlonsoToldo, MP | 1 |
1 review available for melatonin and American Trypanosomiasis
| Article | Year |
|---|---|
T. cruzi infection among aged rats: Melatonin as a promising therapeutic molecule.
Topics: Animals; Antioxidants; Chagas Disease; Melatonin; Rats; Rats, Wistar; Trypanosoma cruzi | 2020 |
14 other studies available for melatonin and American Trypanosomiasis
| Article | Year |
|---|---|
Melatonin decreases circulating
Topics: Animals; Chagas Disease; Heart; Melatonin; Mice; Trypanosoma cruzi | 2021 |
Melatonin: Antioxidant and modulatory properties in age-related changes during Trypanosoma cruzi infection.
Topics: Aging; Animals; Antioxidants; CD28 Antigens; Chagas Disease; Macrophages, Peritoneal; Male; Melatoni | 2017 |
Effects of melatonin on thymic and oxidative stress dysfunctions during Trypanosoma cruzi infection.
Topics: Animals; Antioxidants; Chagas Disease; Male; Melatonin; Oxidative Stress; Rats; Rats, Wistar; Supero | 2018 |
Immunomodulatory properties and anti-apoptotic effects of zinc and melatonin in an experimental model of chronic Chagas disease.
Topics: Animals; Antigens, CD; Apoptosis; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Separ | 2015 |
Immunoregulatory actions of melatonin and zinc during chronic Trypanosoma cruzi infection.
Topics: Animals; Chagas Disease; Forkhead Transcription Factors; Immunologic Factors; Interferon-gamma; Inte | 2015 |
Influence of melatonin therapy and orchiectomy on T cell subsets in male Wistar rats infected with Trypanosoma cruzi.
Topics: Animals; CD3 Complex; CD4-Positive T-Lymphocytes; Central Nervous System Depressants; Chagas Disease | 2009 |
Melatonin and dehydroepiandrosterone combination: does this treatment exert a synergistic effect during experimental Trypanosoma cruzi infection?
Topics: Adjuvants, Immunologic; Animals; Antioxidants; Chagas Disease; Dehydroepiandrosterone; Drug Combinat | 2009 |
Enhanced protection by melatonin and meloxicam combination in experimental infection by Trypanosoma cruzi.
Topics: Animals; Chagas Disease; Dinoprostone; Drug Synergism; Immunologic Factors; Interferon-gamma; Interl | 2010 |
Melatonin and zinc treatment: distinctive modulation of cytokine production in chronic experimental Trypanosoma cruzi infection.
Topics: Animals; Antigens, CD; Cell Count; Cell Proliferation; Chagas Disease; Chronic Disease; Concanavalin | 2011 |
Melatonin in Chagas' disease. Possible therapeutic value.
Topics: Animals; Antioxidants; Central Nervous System Depressants; Chagas Cardiomyopathy; Chagas Disease; Ch | 2011 |
Does orchiectomy enhance the immune-stimulatory effects of melatonin during experimental Chagas' disease?
Topics: Animals; Chagas Disease; Gene Expression Regulation; Interferon-gamma; Lipopolysaccharides; Macropha | 2012 |
Melatonin treatment reduces the severity of experimental Trypanosoma cruzi infection.
Topics: Adjuvants, Immunologic; Animals; Chagas Disease; Heart; Interleukin-2; Male; Melatonin; Myocardium; | 2007 |
Melatonin enhances pro-inflammatory cytokine levels and protects against Chagas disease.
Topics: Animals; Antiprotozoal Agents; Cells, Cultured; Chagas Disease; Cytokines; Female; Humans; Inflammat | 2008 |
Suppressive action of melatonin on the TH-2 immune response in rats infected with Trypanosoma cruzi.
Topics: Analysis of Variance; Animals; Chagas Disease; Concanavalin A; Cytokines; Immunity, Active; Immunity | 2008 |