melatonin has been researched along with Alcoholism in 24 studies
Alcoholism: A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present study was performed in order to establish whether alcoholism modifies the effects of melatonin (MEL) on the neuroendocrine control of growth hormone (GH) secretion." | 7.70 | Alcoholism abolishes the effects of melatonin on growth hormone secretion in humans. ( Coiro, V; Vescovi, PP, 1998) |
| "The melatonin data were correlated with the suppressive effects of dexamethasone (DXT) on cortisol secretion evaluated both during alcohol intake and during abstinence." | 5.28 | Urine melatonin in alcoholic patients: a marker of alcohol abuse? ( Bo, P; Costelli, P; Filippi, U; Fonzi, S; Murialdo, G; Polleri, A; Savoldi, F, 1991) |
| "In this secondary analysis of a pilot clinical trial with individuals with alcohol and nicotine use disorders, we investigate the relationship between serum concentrations of oxytocin, β-endorphin, melatonin, α-melanocyte-stimulating hormone, substance P, and orexin, with objective biomarkers (salivary cotinine and serum γ-glutamyl transferase [GGT]) as well as with self-reported smoking and alcohol drinking." | 4.02 | Brief Report: Relationship Between Cotinine Levels and Peripheral Endogenous Concentrations of Oxytocin, β-Endorphin, and Orexin in Individuals With Both Alcohol and Nicotine Use Disorders. ( Brown, ZE; Haass-Koffler, CL; Kurtis, J; Lee, MR; Leggio, L; Perciballi, R; Swift, RM; Zywiak, WH, 2021) |
| " The present study was performed in order to establish whether alcoholism modifies the effects of melatonin (MEL) on the neuroendocrine control of growth hormone (GH) secretion." | 3.70 | Alcoholism abolishes the effects of melatonin on growth hormone secretion in humans. ( Coiro, V; Vescovi, PP, 1998) |
| " The dosage of melaxen ranged from 3 to 6 mg depending on the respond to the minimal dose." | 2.78 | [An open-label non-comparative study of the efficacy and safety of melaxen in treatment of sleep disorders in alcohol dependent patients during the period of abstinence]. ( Andreeva, NE; Andrianov, FV; Anipchenko, AV; Eryshev, OF, 2013) |
| "Melatonin is a hormone mainly secreted by the pineal gland during the dark phase of the light-dark cycle." | 2.41 | [Melatonin. I. Physiology of its secretion]. ( Bruls, E; Crasson, M; Legros, JJ, 2000) |
| "The melatonin data were correlated with the suppressive effects of dexamethasone (DXT) on cortisol secretion evaluated both during alcohol intake and during abstinence." | 1.28 | Urine melatonin in alcoholic patients: a marker of alcohol abuse? ( Bo, P; Costelli, P; Filippi, U; Fonzi, S; Murialdo, G; Polleri, A; Savoldi, F, 1991) |
| "Melatonin treatment also resulted in reducing daily total fluid intake as well as ethanol consumption in light-deprived hamsters." | 1.26 | Pineal gland and melatonin influence on chronic alcohol consumption by hamsters. ( Rudeen, PK; Symmes, SK, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (20.83) | 18.7374 |
| 1990's | 4 (16.67) | 18.2507 |
| 2000's | 4 (16.67) | 29.6817 |
| 2010's | 4 (16.67) | 24.3611 |
| 2020's | 7 (29.17) | 2.80 |
| Authors | Studies |
|---|---|
| Borisova, AB | 1 |
| Veltishchev, DY | 1 |
| Lisitsyna, TA | 1 |
| Reshetnyak, TM | 1 |
| Seravina, OF | 1 |
| Kovalevskaya, OB | 1 |
| Cheldieva, FA | 1 |
| Abramkin, AA | 1 |
| Bokhan, NA | 1 |
| Roshchina, OV | 1 |
| Simutkin, GG | 1 |
| Levchuk, LA | 1 |
| Ivanova, SA | 1 |
| Osler, M | 1 |
| Jørgensen, MB | 1 |
| Meyrel, M | 1 |
| Rolland, B | 1 |
| Geoffroy, PA | 1 |
| Gendy, MNS | 1 |
| Lagzdins, D | 1 |
| Schaman, J | 1 |
| Le Foll, B | 1 |
| Haass-Koffler, CL | 1 |
| Perciballi, R | 1 |
| Brown, ZE | 1 |
| Lee, MR | 1 |
| Zywiak, WH | 1 |
| Kurtis, J | 1 |
| Swift, RM | 1 |
| Leggio, L | 1 |
| Roehrs, TA | 1 |
| Auciello, J | 1 |
| Tseng, J | 1 |
| Whiteside, G | 1 |
| Kurhaluk, N | 1 |
| Chuffa, LG | 1 |
| Seiva, FR | 1 |
| Fávaro, WJ | 1 |
| Amorim, JP | 1 |
| Teixeira, GR | 1 |
| Mendes, LO | 1 |
| Fioruci-Fontanelli, BA | 1 |
| Pinheiro, PF | 1 |
| Martinez, M | 1 |
| Martinez, FE | 1 |
| Eryshev, OF | 1 |
| Anipchenko, AV | 1 |
| Andreeva, NE | 1 |
| Andrianov, FV | 1 |
| Peres, R | 1 |
| do Amaral, FG | 1 |
| Madrigrano, TC | 1 |
| Scialfa, JH | 1 |
| Bordin, S | 1 |
| Afeche, SC | 1 |
| Cipolla-Neto, J | 1 |
| Conroy, DA | 1 |
| Hairston, IS | 1 |
| Arnedt, JT | 1 |
| Hoffmann, RF | 1 |
| Armitage, R | 1 |
| Brower, KJ | 1 |
| Kühlwein, E | 1 |
| Hauger, RL | 1 |
| Irwin, MR | 1 |
| Borisov, MM | 1 |
| Rudeen, PK | 1 |
| Symmes, SK | 1 |
| Schmitz, MM | 1 |
| Sepandj, A | 1 |
| Pichler, PM | 1 |
| Rudas, S | 1 |
| Coiro, V | 1 |
| Vescovi, PP | 1 |
| Bruls, E | 1 |
| Crasson, M | 1 |
| Legros, JJ | 1 |
| Roehrs, T | 1 |
| Roth, T | 1 |
| Danel, T | 1 |
| Touitou, Y | 1 |
| Wetterberg, L | 1 |
| Aperia, B | 1 |
| Gorelick, DA | 1 |
| Gwirtzman, HE | 1 |
| McGuire, MT | 1 |
| Serafetinides, EA | 1 |
| Yuwiler, A | 1 |
| Murialdo, G | 1 |
| Filippi, U | 1 |
| Costelli, P | 1 |
| Fonzi, S | 1 |
| Bo, P | 1 |
| Polleri, A | 1 |
| Savoldi, F | 1 |
| Veit, I | 1 |
| Dietzel, M | 1 |
| Lesch, OM | 1 |
| Hermann, P | 1 |
| Birsak, L | 1 |
| Reschenhofer, E | 1 |
| Majumdar, SK | 1 |
| Miles, A | 1 |
| Moss, HB | 1 |
| Tamarkin, L | 1 |
| Majchrowicz, E | 1 |
| Martin, PR | 1 |
| Linnoila, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Placebo-controlled, Double -Blind Randomised Trial of Suvorexant in the Management Comorbid Sleep Disorder and Alcohol Dependence[NCT03897062] | Phase 2 | 22 participants (Actual) | Interventional | 2019-08-26 | Terminated (stopped due to Recruitment problems during covid lockdowns resulted in Merck ceasing supply of suvorexant/placebo) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for melatonin and Alcoholism
| Article | Year |
|---|---|
Alterations in circadian rhythms following alcohol use: A systematic review.
Topics: Alcohol Drinking; Alcoholism; Body Temperature; Circadian Rhythm; Dose-Response Relationship, Drug; | 2020 |
Current and potential pharmacological treatment options for insomnia in patients with alcohol use disorder in recovery.
Topics: Alcohol Abstinence; Alcoholism; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Humans | 2020 |
Alcohol and melatonin.
Topics: Alcoholism; Antioxidants; Circadian Rhythm; Ethanol; Humans; Melatonin | 2021 |
[Role of the serotoninergic structures of the brain in alcoholism].
Topics: Acetaldehyde; Alcoholism; Animals; Brain; Brain Chemistry; Carbolines; Cricetinae; Ethanol; Humans; | 1981 |
[Melatonin. I. Physiology of its secretion].
Topics: Alcoholism; Body Constitution; Circadian Rhythm; Cushing Syndrome; Electromagnetic Fields; Female; H | 2000 |
Sleep, sleepiness, and alcohol use.
Topics: Alcohol Drinking; Alcoholism; Animals; Dose-Response Relationship, Drug; Ethanol; Humans; Melatonin; | 2001 |
[Alcohol, chronobiology and sleep].
Topics: Alcoholism; Animals; Chronobiology Disorders; Ethanol; Humans; Melatonin; Sleep Wake Disorders | 2001 |
2 trials available for melatonin and Alcoholism
| Article | Year |
|---|---|
Melatonin for Treatment-Seeking Alcohol Use Disorder patients with sleeping problems: A randomized clinical pilot trial.
Topics: Adult; Aged; Alcoholism; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Me | 2020 |
[An open-label non-comparative study of the efficacy and safety of melaxen in treatment of sleep disorders in alcohol dependent patients during the period of abstinence].
Topics: Administration, Oral; Adult; Alcoholism; Antioxidants; Cognitive Behavioral Therapy; Dose-Response R | 2013 |
15 other studies available for melatonin and Alcoholism
| Article | Year |
|---|---|
Topics: Adolescent; Adult; Aged; Alcoholism; Anhedonia; Antiphospholipid Syndrome; Anxiety; Comorbidity; Dep | 2022 |
Association of benzodiazepines, Z-drugs, pregabalin, and melatonin with traffic accidents: A nationwide cohort and case-crossover study in Danish adults.
Topics: Accidents, Traffic; Adolescent; Adult; Aged; Alcoholism; Benzodiazepines; Chlordiazepoxide; Cohort S | 2022 |
Brief Report: Relationship Between Cotinine Levels and Peripheral Endogenous Concentrations of Oxytocin, β-Endorphin, and Orexin in Individuals With Both Alcohol and Nicotine Use Disorders.
Topics: Adult; Alcohol Drinking; Alcoholism; alpha-MSH; beta-Endorphin; Cotinine; Female; gamma-Glutamyltran | 2021 |
Melatonin and ethanol intake exert opposite effects on circulating estradiol and progesterone and differentially regulate sex steroid receptors in the ovaries, oviducts, and uteri of adult rats.
Topics: Alcoholism; Animals; Estradiol; Ethanol; Female; Melatonin; Ovary; Oviducts; Progesterone; Rats; Rec | 2013 |
Ethanol consumption and pineal melatonin daily profile in rats.
Topics: Acetylserotonin O-Methyltransferase; Alcoholism; Animals; Arylalkylamine N-Acetyltransferase; Circad | 2011 |
Dim light melatonin onset in alcohol-dependent men and women compared with healthy controls.
Topics: Adult; Aged; Alcohol Drinking; Alcoholism; Case-Control Studies; Female; Humans; Light; Male; Melato | 2012 |
Abnormal nocturnal melatonin secretion and disordered sleep in abstinent alcoholics.
Topics: Adult; Alcohol Drinking; Alcoholism; Body Mass Index; Case-Control Studies; Electroencephalography; | 2003 |
Pineal gland and melatonin influence on chronic alcohol consumption by hamsters.
Topics: Alcoholism; Animals; Choice Behavior; Cricetinae; Humans; Male; Melatonin; Mesocricetus; Photic Stim | 1981 |
Disrupted melatonin-secretion during alcohol withdrawal.
Topics: Adult; Alcoholism; Biological Clocks; Female; Humans; Male; Melatonin; Middle Aged; Substance Withdr | 1996 |
Alcoholism abolishes the effects of melatonin on growth hormone secretion in humans.
Topics: Adult; Alcoholism; Human Growth Hormone; Humans; Hypoglycemia; Insulin; Kinetics; Male; Melatonin; M | 1998 |
Age, alcoholism and depression are associated with low levels of urinary melatonin.
Topics: Adult; Age Factors; Alcoholism; Depressive Disorder; Female; Humans; Male; Melatonin; Middle Aged; P | 1992 |
Urine melatonin in alcoholic patients: a marker of alcohol abuse?
Topics: Adult; Alcoholism; Analysis of Variance; Circadian Rhythm; Dexamethasone; Humans; Hydrocortisone; Ma | 1991 |
[Circadian neuroendocrinologic profile in patients with multiple drug abuse].
Topics: Adult; Alcoholism; Circadian Rhythm; Female; Gonadotropins, Pituitary; Hormones; Humans; Hydrocortis | 1986 |
Disturbed melatonin secretion in chronic alcoholism and withdrawal.
Topics: Adult; Alcoholism; Ethanol; Humans; Male; Melatonin; Middle Aged; Substance Withdrawal Syndrome | 1987 |
Pineal function during ethanol intoxication, dependence, and withdrawal.
Topics: Alcohol Withdrawal Delirium; Alcoholism; Analysis of Variance; Animals; Circadian Rhythm; Male; Mela | 1986 |